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Biography
Dr Norita Gildea obtained her PhD in Exercise Physiology in 2017 from Trinity College Dublin. Her doctoral research was centered on exercise intolerance and microvascular dysfunction in individuals with type 2 diabetes. Her research focuses on the mechanisms that affect macrovascular and microvascular function in the context of ageing and metabolic disease. She investigates how exercise and lifestyle interventions influence vascular and metabolic adaptations in individuals with prediabetes, type 2 diabetes and across the lifespan. A key aspect of this work is exploring how personalised exercise prescription can help improve cardiovascular and cerebrovascular function therein, reducing risk factors that are central to reducing the burden of chronic disease.
Publications and Further Research Outputs
- Gildea N, McDermott A, Rocha J, Crognale D, Nevin A, O'Shea D, Green S & Egaña M , Low-volume HIIT and MICT speed VO2 kinetics during high-intensity "work-to-work" cycling with a similar time-course in type 2 diabetes., J Appl Physiol, (133), 2022, p273 - 287Journal Article, 2022, TARA - Full Text
- Green S, Kiely C, O'Connor E, Gildea N, O'Shea D & Egaña M, Differential effects of sex on adaptive responses of skeletal muscle vasodilation to exercise training in type 2 diabetes., J Diabetes Complications, (36), 2022Journal Article, 2022
- Egaña M, Allen L, Gleeson K, Gildea N & Warmington S, Post-exercise cold water immersion does not improve subsequent 4-km cycling time-trial compared with passive and active recovery in normothermia, Front Sports Act Living, (25), 2021Journal Article, 2021
- Gildea N, McDermott A, Rocha J, Green S, O'Shea D & Egaña M, Time-course of VO2 kinetics responses during moderate-intensity exercise subsequent to HIIT versus moderate-intensity continuous training in type 2 diabetes, J Appl Physiol , (130), 2021, p1646 - 1659Journal Article, 2021
- Gildea N, McDermott A, Rocha J, O'Shea D, Green S & Egaña M., Time course of changes in VO2peak and O2 extraction during ramp cycle exercise following HIIT vs moderate-intensity continuous training in type 2 diabetes., Am J Physiol Regul Integr Comp Physiol, (320), 2021, p683 - 696Journal Article, 2021
- Gildea N, Rocha J, O'Shea D, Green S & Egaña M., Priming exercise accelerates pulmonary oxygen uptake kinetics during "work-to-work" cycle exercise in middle-aged individuals with type 2 diabetes., Eur J Appl Physiol, (121), 2021, p409 - 423Journal Article, 2021
- Green S, Kiely C, O'Connor E, Gildea N, O'Shea D & Egaña M., Effects of exercise training and sex on dynamic responses of O2 uptake in type 2 diabetes., Appl Physiol Nutr Metab, (45), 2020, p865 - 874Journal Article, 2020
- Gildea N, Rocha J, McDermott A, O'Shea D, Green S & Egaña. , Influence of type 2 diabetes on muscle deoxygenation during ramp incremental cycle exercise in middle-aged individuals., Respir Physiol Neurobiol., (269), 2019Journal Article, 2019
- Gildea N, McDermott A, Rocha J, Nevin A, O'Shea D, Green S & Egaña M, Influence of HIIT and MICT on the effects of "priming" exercise on oxygen uptake kinetics during moderate-intensity exercise in individuals with type 2 diabetes, Proc Physiol Soc., Europhysiology , Copenhagen, Denmark, September, 2022Conference Paper, 2022
- Gildea N, McDermott A, Rocha J, Nevin A, O'Shea D, Green S & Egaña M., Time Course Adaptations in Oxygen Uptake and Muscle Deoxygenation Kinetics During Heavy-Intensity Exercise Initiated from an Elevated Baseline Subsequent to a 12 Week Low-Volume, High-Intensity Interval Training Intervention or Moderate-Intensity Continuous Training in Type 2 Diabetes, FASEB J, Experimental Biology, Orlando, USA, 2019, 33, (1), FASEB J, 2019Conference Paper, 2019
- McDermott A, Nevin A, Gildea N, Rocha J, Crognale D, O'Shea D, Green S & Egaña M, Time course adaptations in cardiorespiratory fitness and fractional oxygen extraction with low-volume, high- intensity interval training and moderate-intensity continuous training in people with type 2 diabetes., Proc Physiol Soc, Europhysiology, London, UK, 2018, 41, Proc Physiol Soc, 2018Conference Paper, 2018
- Nevin A, McDermott A, Gildea N, Rocha J, Crognale D, O'Shea D, Green S & Egaña M., he effects of low-volume high-intensity interval training on pulmonary oxygen uptake and muscle deoxygenation kinetics during heavy-intensity exercise in type 2 diabetes., Europhysiology, London, UK, 2018, (41), Proc Physiol Soc, 2018Conference Paper, 2018
- Gildea N, McDermott A, Rocha J, Crognale D, Nevin A, O'Shea D, Green S & Egaña M., Time course adaptations in oxygen uptake and muscle deoxygenation kinetics during submaximal exercise subsequent to a 12 week moderate-intensity continuous training or low-volume, high-intensity interval training intervention in type 2 diabetes., Proc Physiol Soc, Europhysiology 2018, London, UK, 2018, 41, Proc Physiol Soc, 2018Conference Paper, 2018
- Gildea N, Rocha J, Green S, O'Shea D & Egaña M, Influence of priming exercise on pulmonary oxygen uptake kinetics during heavy-intensity cycle exercise from an elevated baseline in type 2 diabetes., FASEB J, Experimental Biology , San Diego (USA), 2018, FASEB J, 2018Conference Paper, 2018
- Rocha J, Gildea N, Green S, O'Shea D & Egaña M., Influence of priming exercise on pulmonary oxygen uptake and muscle deoxygenation kinetics during heavy-intensity cycle exercise in type 2 diabetes., Eur J Appl Physiol, 2016Journal Article, 2016
- Gildea N, Rocha J, Corish O, Comerford J & Egaña M., The effects of the low recumbent body position in muscle deoxygenation during ramp incremental exercise, European College of Sports Sciences 2016, Vienna, Austria, 2016, 2016Conference Paper, 2016
- Rocha J, Gildea N, Green S, O'Shea D & Egaña M., Influence of priming exercise and type 2 diabetes on VO2 and NIRS kinetics during submaximal exercise., Proc Physiol Soc , The Biomedical Basis of Elite Performance, London, UK, 2016, (35), 2016Conference Paper, 2016
- Gildea N, Rocha J, Green S, O'Shea D & Egaña M., The effect of type 2 diabetes in muscle deoxygenation during ramp incremental cycling exercise, Proc Physiol Soc, The Biomedical Basis of Elite Performance, London, UK, 2016, 2016Conference Paper, 2016
- McDermott A, Nevin A, Gildea N, Rocha J, O'Shea D, Egaña M., Muscle deoxygenation during ramp incremental cycle exercise in older adults with type 2 diabetes., European Journal of Applied Physiology, Feb, (124(2)), 2024, p561 - 571Journal Article, 2024, URL
- Rocha J, Gildea N, O'Shea D, Green S, Egaña M, Priming exercise accelerates oxygen uptake kinetics during high-intensity cycle exercise in middle-aged individuals with type 2 diabetes., Frontiers in Physiology, 18, (13), 2022Journal Article, 2022
- Gildea N, Rocha J, O'Shea D, Green S & Egaña M, Influence of priming exercise on oxygen uptake and muscle deoxygenation kinetics during moderate-intensity cycling in type 2 diabetes., Journal of Applied Physiology, 127, (4), 2019, p1140 - 1149Journal Article, 2019
- Murphy E, Rocha J, Gildea N, Green S and Egaña M., Venous occlusion plethysmography vs. Doppler ultrasound in the assessment of leg blood flow kinetics during different intensities of calf exercise., European Journal of Applied Physiology , 118, (2), 2018, p249 - 260Journal Article, 2018
- E. Curtin, M.E. Weston, P. Buys, T. Bissoonauth, H. Al-Shammary, O. Ojelabi, A. Osman, J. Li, T. Wickramasinghe, Y. Lim, Z. Ching, M. Carey, E. Rooney, M. Egaña, N. Gildea, The effects of sex and fitness on cerebrovascular reactivity and cerebral autoregulation in healthy young adults., Proc Physiol Soc, Physiology in Focus 2024, Newcastle UK, July 2024, 2024Conference Paper, 2024
- P. Buys, E. Curtin, C. Brady, C. Rooney, A. Alshahrabally, P. McConkey, S. Donohoe, H. Darwish, S. Spring, G. Hagon, C. Gallagher, A. Mahon, N. Gildea, M. Egaña, M.E. Weston., The acute effect of maximal sprint exercise on cerebrovascular reactivity in healthy young adults, Proc Physiol Soc, Physiology in Focus 2024, Newcastle UK, July 2024, 2024Conference Paper, 2024
- M.E. Weston, P. Buys, E. Curtin, D. Guichard, E. Harbison, A. Croce, E. Ng, C. Delle Monache, A. Maero, G. Tan Tan, T. Khoo, A. Sreekanth, N. Gildea, M. Egaña, Dynamic cerebral autoregulation is unchanged following maximal sprint exercise in healthy young adults, Proc Physiol Soc, Physiology in Focus 2024, Newcastle UK, July 2024, 2024Conference Paper, 2024
- O'Connor E, Kiely C, Gildea N, O'Shea D, Green S, Egaña M, Effects of pioglitazone with and without exercise training on cardiorespiratory fitness and oxygen uptake kinetics in type 2 diabetes., Diabetes, Obesity and Metabolism., 2025Journal Article, 2025
- Weston M, Curtin E, Buys P, Gildea N, Egaña, The acute effect of maximal sprint exercise on dynamic cerebral autoregulation in healthy young adults., Physiological Reports, 2025Journal Article, 2025
- Weston, M; Curtin, E; Buys, P; Gildea, N; Egaña, M, Dynamic cerebral autoregulation remains intact following maximal sprint exercise in young men and women., The 30th European College of Sports Science (ECSS) Annual Congress 2025, Rimini, Italy, July 2025, 2025Conference Paper, 2025
- Buys, P; Weston, M; Curtin, E; Gildea, N; Egaña, M, The acute effects of moderate-intensity continuous, resistance, and concurrent exercise on cerebrovascular reactivity to hypocapnia in healthy young adults, The 30th European College of Sports Science (ECSS) Annual Congress 2025, Rimini, Italy, July 2025, 2025Conference Paper, 2025
- Benefits of Exercise in, editor(s)Neil Heron & Nicolas Mahony , Oxford Handbook of Sports and Exercise Medicine, Oxford University Press, Oxford University Press, 2025, [W. Williamson & N Gildea]Book Chapter, 2025
- Curtin E, Buys P, Weston M, Egana M & Gildea N, The Acute Effect of Aerobic, Resistance, and Concurrent Exercise on Dynamic Cerebral Autoregulation In Healthy Young Adults, The 30th European College of Sports Science (ECSS) Annual Congress 2025, Rimini, Italy, July 2025, 2025Conference Paper, 2025
Research Expertise
Dr. Gildea's research focuses on the mechanisms that affect macrovascular and microvascular function in the context of ageing and metabolic disease. She investigates how exercise and lifestyle interventions influence vascular and metabolic adaptations in individuals with prediabetes, type 2 diabetes and across the lifespan. A key aspect of this work is exploring how personalised exercise prescription and other novel therapeutic interventions can help improve cardiovascular and cerebrovascular function therein, reducing risk factors that are central to reducing the burden of chronic disease. More recently, her research has extended to individuals living with neurodiversity, who face heightened risks of mental health challenges and the development of non-communicable diseases. This evolving strand of work explores how tailored lifestyle interventions"delivered in part through innovative digital applications"can support both physical and mental health outcomes in these populations, improving accessibility and personalisation of care. Her work contributes to advancing translational science and public health efforts by informing strategies to delay stroke, cognitive decline, and dementia, with meaningful implications for patients, families, healthcare systems, and society at large.
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