The Synaptic Gene (SynaG) Project

Project Lead: Prof Louise Gallagher

The goal of the SynaG study is to investigate brain development, cognition, emotion and social skills in people with NRXN1 deletions to better understand if there are any features that are characteristic of NRXN1 deletions. We know that some people may develop a neurodevelopmental condition such as autism, while others do not.

​We compare to individuals who have autism with no known genetic condition, and to typically developing individuals without any rare genetic condition or diagnosis of a neurodevelopmental condition.

This project is a collaboration between researchers at King’s College London and Trinity College Dublin to investigate rare genetic conditions associated with neurodevelopmental conditions such as autism. This study is part of a European consortium called AIMS-2-TRIALS.

We are recruiting individuals with 2p16.3 (NRXN1) deletion.

If you take part in this study you will be asked to:

  1. Provide a blood or saliva sample
  2. Fill out questionnaires
  3. Complete interviews

The following will be completed at the neurocognition lab at Trinity Centre for Health Sciences

  1. Play games on a tablet
  2. Complete pen and paper tasks
  3. Complete EEG and Eye tracking

If you are interested in joining our study or finding out more email us at: recruitmentNRG@tcd.ie