Prof. Mark Little and researchers from Trinity College Dublin have answered the HRB COVID-19 pandemic rapid response funding call. The Renal Inflammation Group are working on a COVID-19 project called DeCOmPRESS, which stands for ‘defining the disease course and immune profile of COVID-19 in the immunosuppressed patient’. Our team want to better understand how the immune system responds to the SARS-COV-2 virus and in patients who are taking immunosuppressive medications. This will help us provide clear guidance to patients with respect to cocooning and their current use of immunosuppressant medication. Watch this short video from Prof. Little explaining the study.
ANCA-vasculitis patients currently enrolled in the RKD Biobank are eligible for DeCOmPRESS. Patients will be split into different groups based on the treatment they have received for AAV and their responses to COVID-19 will be compared. The study process can be summarised in the figure below. If you have contracted COVID-19 please contact email@example.com. Please continue to follow government guidelines on social distancing and advice on protecting those most at risk. Visit our COVID-19 guidance page for vasculitis-specific advice.
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If you have any questions about the study or you are interested in participating please contact firstname.lastname@example.org.
Study Contact Details
|Chief Investigator||Prof Mark Little||Trinity Health Kidney Centre, Tallaght University Hospital, Tallaght, Dublin 24|
|Co-Applicants||Dr Lina Zgaga||Department of Public Health and Primary Care, Trinity College Dublin|
|Dr. Michelle O'Shaughnessy||Department of Renal Medicine, Cork University Hospital|
|Project Manager||Ms. Emma Leacy||Trinity Translational Medicine Institute, St. James Hospital Dublin 8|
|Biobank Coordinator||Dr. Alan Kennedy||Trinity Translational Medicine Institute, St. James Hospital Dublin 8|
Local Study Site Managers
|Clinical Site||Key Contact||Clinical Role|
|Tallaght University Hospital||Prof Mark Little||Consultant Nephrologist|
|St. Vincent's University Hospital||Prof Eamonn Molloy||Consultant Rheumatologist|
|St. James’s Hospital||Dr Niall Conlon||Consultant Immunologist|
|Beaumont Hospital||Prof Mark Little||Consultant Nephrologist|
|Galway University Hospital||Prof Matt Griffin||Professor of Transplant Immunology|
|Cork University Hospital||
Dr Michelle O’Shaughnessy
Dr Michael Clarkson
Consultant NephrologistConsultant Nephrologist