Imaging and Cognition

Title	Authors	Publication	Spec
Genetic influences on schizophrenia and subcortical volumes: large-scale proof of concept (pdf)	Franke B, et al.	Nature Neuroscience, 2016	A useful guide to the state of the field in 2015 showing that landmark discoveries in schizophrenia are beginning to be replicated in other psychiatric disorders.
Common genetic variants influence human subcortical brain structures (pdf)	Hibar DP, et al.	Nature, 2015	In this large collaborative study we show that common risk variants aggregate in biological pathways and that these pathways are shared between schizophrenia, bipolar disorder and depression.
Effects of MIR137 on fronto-amygdala functional connectivity	Mothersill O, et al.	Neuroimage, 2014	In the largest reported genome-wide association study (GWAS) of schizophrenia we identify associations spanning 108 loci: 83 of these were new findings
Effects of a novel schizophrenia risk variant at CNNM2 on brain structure and attributional style (pdf)	Rose EJ, et al.	British Journal of Psychiatry, 2014	In one of the first published schizophrenia whole exome studies we report an excess of mutations involving genes that regulate transcription including CHD8, MECP2 and HUWE1.
Psychosis susceptibility gene ZNF804A and cognitive performance in schizophrenia	Walters JT, et al.	Archives of General Psychiatry, 2010	We find evidence that a rare duplication at this gene, likely inherited from a single founder, increases risk of schizophrenia and bipolar disorder in Ireland and other populations.

Cognition

Title	Authors	Publication	Spec
Computerized working-memory focused cognitive remediation therapy for psychosis: a preliminary study (pdf)	Hargreaves A, et al.	Nature Neuroscience, 20150	In this large collaborative study we show that common risk variants aggregate in biological pathways and that these pathways are shared between schizophrenia, bipolar disorder and depression.
Variability in working memory performance explained by epistasis vs polygenic scores in the ZNF804A pathway (pdf)	Nicodemus KK, et al.	JAMA Psychiatry, 2014	In the largest reported genome-wide association study (GWAS) of schizophrenia we identify associations spanning 108 loci: 83 of these were new findings.
Effects of ZNF804A on auditory P300 response in schizophrenia (pdf)	O'Donoghue T, et al.	Translational Psychiatry, 2014	In one of the first published schizophrenia whole exome studies we report an excess of mutations involving genes that regulate transcription including CHD8, MECP2 and HUWE1.
Mood congruent psychotic symptoms and specific cognitive deficits in carriers of the schizophrenia risk variant at MIR-137 (pdf)	Cummings E, et al.	Molecular Psychiatry, 2012	In our first major sequencing project loss of function variants were over-represented in Neurexin and Neuroligin Interacting Protein genes: neatly mirroring the finding from our earlier pathway analysis of SNP data.