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Immunology

 

Staff

Leahy Ronan Dr  Paediatric Immunologist
Molloy Eleanor Professor Professor of Paediatrics & Child Health

Professor Ronan Leahy
Clinical Professor, Paediatrics

Publications and Further Research Outputs

Peer-Reviewed Publications

Ghimenton E, Flinn A, Lum SH, Leahy TR, Nademi Z, Owens S, Williams E, Flood T, Hambleton S, Slatter M, Gennery AR., Hematopoietic Cell Transplantation for Adenosine Deaminase Severe Combined Immunodeficiency-Improved Outcomes in the Modern Era., Journal of clinical immunology, 2022 Journal Article, 2022 DOI

Mulvihill C, Fitzgerald K, O'Regan E, Healy CM, Leahy TR., Successful treatment of oral potentially malignant lesions with ruxolitinib in STAT3 gain-of-function disease., Oral oncology, 132, 2022, p106015 Journal Article, 2022 DOI

Treston B, Petty-Saphon N, Collins A, Murray S, Colgan A, Fitzgerald E, Hassan M, Forde K, O'Farrell A, Sayers G, Linnane N, Franklin O, McMahon C, Leahy TR, Gavin P., Multisystem inflammatory syndrome in the context of paediatric COVID-19 infection in the Republic of Ireland April 2020 to April 2021., Acta Paediatr, 111, (12), 2022, p2344-2351 Journal Article, 2022 DOI

Clifford D, Moloney F, Leahy TR, Murray DM., Roifman syndrome: a description of further immunological and radiological features. , BMJ case reports, 15, (4), 2022, pe249109 Journal Article, 2022 DOI

Lum SH, Greener S, Perez-Heras I, Drozdov D, Payne RP, Watson H, Carruthers K, January R, Nademi Z, Owens S, Williams E, Waugh S, Burton-Fanning S, Leahy TR, Cant A, Abinun M, Flood T, Hambleton S, Gennery AR, Slatter M., T-replete HLA-matched grafts vs T-depleted HLA-mismatched grafts in inborn errors of immunity., Blood advances, 6, (4), 2022, p1319-1328 Journal Article, 2022 DOI

Molloy B, Jones ER, Linhares ND, Buckley PG, Leahy TR, Lynch B, Knerr I, King MD, Gorman KM., Uniparental disomy screen of Irish rare disorder cohort unmasks homozygous variants of clinical significance in the TMCO1 and PRKRA genes., Frontiers in genetics, 13, 2022, p945296 Journal Article, 2022 DOI

Cox F, Bigley V, Irvine A, Leahy R, Conlon N., PAMI Syndrome: Two Cases of an Autoinflammatory Disease with an ALPS-Like Phenotype., Journal of clinical immunology, 42, (5), 2022, p955-958 Journal Article, 2022 DOI

Foley DJ, Connell AR, Gonzalez G, Connell J, Leahy TR, De Gascun C, Hassan J., Mumps-specific IgG, IgG subclasses and neutralization titres to the vaccine and outbreak mumps strains differ in vaccinated healthy controls, breakthrough mumps infection cases and naturally infected individuals., Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 157, 2022, p105296 Journal Article, 2022 DOI

Leiding JW, Vogel TP, Santarlas VGJ, Mhaskar R, Smith MR, Carisey A, Vargas-Hernández A, Silva-Carmona M, Heeg M, Rensing-Ehl A, Neven B, Hadjadj J, Hambleton S, Ronan Leahy T, Meesilpavikai K, Cunningham-Rundles C, Dutmer CM, Sharapova SO, Taskinen M, Chua I, Hague R, Klemann C, Kostyuchenko L, Morio T, Thatayatikom A, Ozen A, Scherbina A, Bauer CS, Flanagan SE, Gambineri E, Giovannini-Chami L, Heimall J, Sullivan KE, Allenspach E, Romberg N, Deane SG, Prince BT, Rose MJ, Bohnsack J, Mousallem T, Jesudas R, Santos Vilela MMD, O'Sullivan M, Pachlopnik Schmid J, Pr"hová Š, Klocperk A, Rees M, Su H, Bahna S, Baris S, Bartnikas LM, Chang Berger A, Briggs TA, Brothers S, Bundy V, Chan AY, Chandrakasan S, Christiansen M, Cole T, Cook MC, Desai MM, Fischer U, Fulcher DA, Gallo S, Gauthier A, Gennery AR, Gonçalo Marques J, Gottrand F, Grimbacher B, Grunebaum E, Haapaniemi E, Hämäläinen S, Heiskanen K, Heiskanen-Kosma T, Hoffman HM, Gonzalez-Granado LI, Guerrerio AL, Kainulainen L, Kumar A, Lawrence MG, Levin C, Martelius T, Neth O, Olbrich P, Palma A, Patel NC, Pozos T, Preece K, Lugo Reyes SO, Russell MA, Schejter Y, Seroogy C, Sinclair J, Skevofilax E, Suan D, Suegeorgz D, Szabolcs P, Velasco H, Warnatz K, Walkovich K, Worth A, STAT3 GOF Working Group members, Seppänen MRJ, Torgerson TR, Sogkas G, Ehl S, Tangye SG, Cooper MA, Milner JD, Forbes Satter LR., Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome., The Journal of allergy and clinical immunology, 2022, pS0091-6749(22)01182-4 Journal Article, 2022 DOI

Flinn AM, Flood T, Prendiville T, Gennery AR, Leahy TR., Adenosine Deaminase Deficient SCID with Myocardial Hypertrophy., Journal of clinical immunology, 2021 Journal Article, 2021 DOI

Allen J, Zareen Z, Doyle S, Whitla L, Afzal Z, Stack M, Franklin O, Green A, James A, Leahy TR, Quinn S, Elnazir B, Russell J, Paran S, Kiely P, Roche EF, McDonnell C, Baker L, Hensey O, Gibson L, Kelly S, McDonald D, Molloy EJ., Multi-Organ Dysfunction in Cerebral Palsy., Frontiers in pediatrics, 9, 2021, p668544 Journal Article, 2021 DOI

Burns H, Collins A, Marsden P, Flood TJ, Slatter MA, Booth C, Xu-Bayford J, Leahy TR., Severe Combined Immunodeficiency (SCID)-the Irish Experience., Journal of clinical immunology, 2021 Journal Article, 2021 DOI

Kelleher KJ, Russell J, Killeen OG, Leahy TR., Treatment-recalcitrant laryngeal sarcoidosis responsive to sirolimus., BMJ case reports, 13, (8), 2020 Journal Article, 2020 DOI

Eisenberg R, Gans MD, Leahy TR, Gothe F, Perry C, Raffeld M, Xi L, Blackstone S, Ma C, Hambleton S, Milner JD., JAK inhibition in early-onset somatic, nonclonal STAT5B gain-of-function disease., The journal of allergy and clinical immunology. In practice, 2020 Journal Article, 2020 DOI

Ali A, Butler KM, Brenner C, Paran S, Gallagher T, El Delaimi F, Chiodini PL, Leahy TR., Hepatic Cystic Echinococcosis (Hydatid Cyst) in a Six Year Old., Irish medical journal, 113, (4), 2020, p61 Journal Article, 2020 DOI

Alsaleemi A, O'Connor C, Irvine AD, Leahy TR., Topical cidofovir for the treatment of recalcitrant viral warts and molluscum contagiosum in Jacobsen syndrome., Pediatric dermatology, 37, (6), 2020, p1191-1192 Journal Article, 2020 DOI

Connell AR, Connell J, Leahy TR, Hassan J., Mumps Outbreaks in Vaccinated Populations-Is It Time to Re-assess the Clinical Efficacy of Vaccines?, Frontiers in immunology, 11, 2020, p2089 Journal Article, 2020 DOI

Dean Huggard, Lynne Kelly, Emer Ryan, Fiona McGrane, Niamh Lagan, Edna Roche, Joanne Balfe, T. Ronan Leahy, Orla Franklin, Derek G. Doherty, Eleanor J. Molloy, Increased systemic inflammation in children with Down syndrome, Cytokine, 127, 2020, p154938 Journal Article, 2020 DOI TARA - Full Text

Hadjadj J, Castro CN, Tusseau M, Stolzenberg MC, Mazerolles F, Aladjidi N, Armstrong M, Ashrafian H, Cutcutache I, Ebetsberger-Dachs G, Elliott KS, Durieu I, Fabien N, Fusaro M, Heeg M, Schmitt Y, Bras M, Knight JC, Lega JC, Lesca G, Mathieu AL, Moreews M, Moreira B, Nosbaum A, Page M, Picard C, Ronan Leahy T, Rouvet I, Ryan E, Sanlaville D, Schwarz K, Skelton A, Viallard JF, Viel S, Villard M, Callebaut I, Picard C, Walzer T, Ehl S, Fischer A, Neven B, Belot A, Rieux-Laucat F., Early-onset autoimmunity associated with SOCS1 haploinsufficiency., Nature communications, 11, (1), 2020, p5341 Journal Article, 2020 DOI

Kelly E, Leahy R, McDermott M, Connor S, Kyne L, Irvine A, Dvorakova V, Browne F, Watson R., Persistent pruritic subcutaneous nodules at injection sites and other delayed type hypersensitivity reactions to aluminium adsorbed vaccines in Irish children: A case series., Acta Paediatr, 109, (12), 2020, p2692-2693 Journal Article, 2020 DOI

Niamh Lagan, Dean Huggard, Fiona Mc Grane, Timothy Ronan Leahy, Orla Franklin, Edna Roche, David Webb, Aengus O'Maricaigh, Des Cox, Afif Elkuffash, Peter Greally, Joanne Balfe, Eleanor J Molloy, Multiorgan involvement and management in children with Down Syndrome, Acta Paediatrica, (1), 2020 Journal Article, 2020 DOI

Omer M, Melo AM, Kelly L, Mac Dermott EJ, Leahy TR, Killeen O, Saugstad OD, Savani RC, Molloy EJ., Emerging Role of the NLRP3 Inflammasome and Interleukin-1ß in Neonates., Neonatology, 117, (5), 2020, p545-554 Journal Article, 2020 DOI

Kaleviste E, Saare M, Leahy TR, Bondet V, Duffy D, Mogensen TH, Jørgensen SE, Nurm H, Ip W, Davies EG, Sauer S, Syvänen AC, Milani L, Peterson P, Kisand K., Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined., European journal of immunology, 49, (5), 2019, p790-800 Journal Article, 2019 DOI

Dorjbal B, Stinson JR, Ma CA, Weinreich MA, Miraghazadeh B, Hartberger JM, Frey-Jakobs S, Weidinger S, Moebus L, Franke A, Schäffer AA, Bulashevska A, Fuchs S, Ehl S, Limaye S, Arkwright PD, Briggs TA, Langley C, Bethune C, Whyte AF, Alachkar H, Nejentsev S, DiMaggio T, Nelson CG, Stone KD, Nason M, Brittain EH, Oler AJ, Veltri DP, Leahy TR, Conlon N, Poli MC, Borzutzky A, Cohen JI, Davis J, Lambert MP, Romberg N, Sullivan KE, Paris K, Freeman AF, Lucas L, Chandrakasan S, Savic S, Hambleton S, Patel SY, Jordan MB, Theos A, Lebensburger J, Atkinson TP, Torgerson TR, Chinn IK, Milner JD, Grimbacher B, Cook MC, Snow AL., Hypomorphic caspase activation and recruitment domain 11 (CARD11) mutations associated with diverse immunologic phenotypes with or without atopic disease., The Journal of allergy and clinical immunology, 143, (4), 2019, p1482-1495 Journal Article, 2019 DOI

McCarthy KN, Leahy TR, Murray DM., Listeria Meningitis in an Immunocompetent Child: Case Report and Literature Review, Irish medical journal, 112, (5), 2019, p939 Journal Article, 2019 DOI

Klemann C, Camacho-Ordonez N, Yang L, Eskandarian Z, Rojas-Restrepo JL, Frede N, Bulashevska A, Heeg M, Al-Ddafari MS, Premm J, Seidl M, Ammann S, Sherkat R, Radhakrishnan N, Warnatz K, Unger S, Kobbe R, Hüfner A, Leahy TR, Ip W, Burns SO, Fliegauf M, Grimbacher B., Clinical and Immunological Phenotype of Patients With Primary Immunodeficiency Due to Damaging Mutations in NFKB2., Frontiers in immunology, 10, 2019, p297 Journal Article, 2019 DOI

Anzilotti C, Swan DJ, Boisson B, Deobagkar-Lele M, Oliveira C, Chabosseau P, Engelhardt KR, Xu X, Chen R, Alvarez L, Berlinguer-Palmini R, Bull KR, Cawthorne E, Cribbs AP, Crockford TL, Dang TS, Fearn A, Fenech EJ, de Jong SJ, Lagerholm BC, Ma CS, Sims D, van den Berg B, Xu Y, Cant AJ, Kleiner G, Leahy TR, de la Morena MT, Puck JM, Shapiro RS, van der Burg M, Chapman JR, Christianson JC, Davies B, McGrath JA, Przyborski S, Santibanez Koref M, Tangye SG, Werner A, Rutter GA, Padilla-Parra S, Casanova JL, Cornall RJ, Conley ME, Hambleton S., An essential role for the Zn2+ transporter ZIP7 in B cell development., Nature Immunology, 2019 Journal Article, 2019 DOI

Al Shehri T, Gilmour K, Gothe F, Loughlin S, Bibi S, Rowan AD, Grainger A, Mohanadas T, Cant AJ, Slatter MA, Hambleton S, Lilic D, Leahy TR., Novel Gain-of-Function Mutation in Stat1 Sumoylation Site Leads to CMC/CID Phenotype Responsive to Ruxolitinib., Journal of clinical immunology, 39, (8), 2019, p776-785 Journal Article, 2019 DOI

Huggard D, Koay WJ, Kelly L, McGrane F, Ryan E, Lagan N, Roche E, Balfe J, Leahy TR, Franklin O, Moreno-Oliveira A, Melo AM, Doherty DG, Molloy EJ., Altered Toll-Like Receptor Signalling in Children with Down Syndrome., Mediators of inflammation, 2019, 2019, p4068734 Journal Article, 2019 DOI

Smyth AE, Kaleviste E, Snow A, Kisand K, McMahon CJ, Cant AJ, Leahy TR, Aortic Calcification in a Patient with a Gain-of-Function STAT1 Mutation., Journal of clinical immunology, 2018 Journal Article, 2018 DOI

Kernan RJ, Gavin PJ, Butler KM, Leahy TR, Lynch B, Leonard J., Expanding the Spectrum of Post-malaria Neurologic Syndrome in the Pediatric Population., Pediatric Infectious Disease Journal, 2018 Journal Article, 2018 DOI

Al Dhanhani H, Al Shehri T, Lilic D, Buddles M, Kisand K, Maccari ME, Leahy TR., Double Trouble? CMC with a Mutation in both AIRE and STAT1., Journal of Clinical Immunology, 2018 Journal Article, 2018 DOI

Cura Daball P, Ventura Ferreira MS, Ammann S, Klemann C, Lorenz MR, Warthorst U, Leahy TR, Conlon N, Roche J, Soler-Palacín P, Garcia-Prat M, Fuchs I, Fuchs S, Beier F, Brümmendorf TH, Speckmann C, Olbrich P, Neth O, Schwarz K, Ehl S, Rensing-Ehl A., CD57 identifies T cells with functional senescence before terminal differentiation and relative telomere shortening in patients with activated PI3 kinase delta syndrome., Immunology and Cell biology, 2018 Journal Article, 2018 DOI

Dorjbal B, Stinson JR, Ma CA, Weinreich MA, Miraghazadeh B, Hartberger JM, Frey-Jakobs S, Weidinger S, Moebus L, Franke A, Schäffer AA, Bulashevska A, Fuchs S, Ehl S, Limaye S, Arkwright PD, Briggs TA, Langley C, Bethune C, Whyte AF, Alachkar H, Nejentsev S, DiMaggio T, Nelson CG, Stone KD, Nason M, Brittain EH, Oler AJ, Veltri DP, Leahy TR, Conlon N, Poli MC, Borzutzky A, Cohen JI, Davis J, Lambert MP, Romberg N, Sullivan KE, Paris K, Freeman AF, Lucas L, Chandrasakan S, Savic S, Hambleton S, Patel SY, Jordan MB, Theos A, Lebensburger J, Atkinson TP, Torgerson TR, Chinn IK, Milner JD, Grimbacher B, Cook MC, Snow AL., Hypomorphic CARD11 mutations associated with diverse immunologic phenotypes with or without atopic disease. , Journal of Allergy and Clinical Immunology, 2018 Journal Article, 2018 DOI

Huggard D, McGrane F, Lagan N, Roche E, Balfe J, Leahy TR, Franklin O, Moreno A, Melo AM, Doherty DG, Molloy EJ, Altered endotoxin responsiveness in healthy children with Down syndrome., BMC immunology, 2018 Journal Article, 2018 TARA - Full Text DOI

Murad A, Leahy TR, Lenane P., Acute Genital Swelling Heralding C1 Esterase Inhibitor Deficiency in a Child., Pediatric dermatology, 34, (5), 2017, pe277-e278 Journal Article, 2017 DOI

Coulter TI, Chandra A, Bacon CM, Babar J, Curtis J, Screaton N, Goodlad JR, Farmer G, Steele CL, Leahy TR, Doffinger R, Baxendale H, Bernatoniene J, Edgar JD, Longhurst HJ, Ehl S, Speckmann C, Grimbacher B, Sediva A, Milota T, Faust SN, Williams AP, Hayman G, Kucuk ZY, Hague R, French P, Brooker R, Forsyth P, Herriot R, Cancrini C, Palma P, Ariganello P, Conlon N, Feighery C, Gavin PJ, Jones A, Imai K, Ibrahim MA, Markelj G, Abinun M, Rieux-Laucat F, Latour S, Pellier I, Fischer A, Touzot F, Casanova JL, Durandy A, Burns SO, Savic S, Kumararatne DS, Moshous D, Kracker S, Vanhaesebroeck B, Okkenhaug K, Picard C, Nejentsev S, Condliffe AM, Cant AJ., Clinical spectrum and features of activated phosphoinositide 3-kinase " syndrome: A large patient cohort study., The Journal of allergy and clinical immunology, 139, (2), 2017, p597-606.e4 Journal Article, 2017 DOI

Ma CA, Xi L, Cauff B, DeZure A, Freeman AF, Hambleton S, Kleiner G, Leahy TR, O'Sullivan M, Makiya M, O'Regan G, Pittaluga S, Niemela J, Stoddard J, Rosenzweig SD, Raffeld M, Klion AD, Milner JD., Somatic STAT5b gain-of-function mutations in early onset nonclonal eosinophilia, urticaria, dermatitis, and diarrhea., Blood, 129, (5), 2017, p650-653 Journal Article, 2017 DOI

Petersen BS, August D, Abt R, Alddafari M, Atarod L, Baris S, Bhavsar H, Brinkert F, Buchta M, Bulashevska A, Chee R, Cordeiro AI, Dara N, Dückers G, Elmarsafy A, Frede N, Galal N, Gerner P, Glocker EO, Goldacker S, Hammermann J, Hasselblatt P, Havlicekova Z, Hübscher K, Jesenak M, Karaca NE, Karakoc-Aydiner E, Kharaghani MM, Kilic SS, Kiykim A, Klein C, Klemann C, Kobbe R, Kotlarz D, Laass MW, Leahy TR, Mesdaghi M, Mitton S, Neves JF, Öztürk B, Pereira LF, Rohr J, Restrepo JLR, Ruzaike G, Saleh N, Seneviratne S, Senol E, Speckmann C, Tegtmeyer D, Thankam P, van der Werff Ten Bosch J, von Bernuth H, Zeissig S, Zeissig Y, Franke A, Grimbacher B., Targeted Gene Panel Sequencing for Early-onset Inflammatory Bowel Disease and Chronic Diarrhea., Inflammatory bowel diseases, 23, (12), 2017, p2109-2120 Journal Article, 2017 DOI

Davies EG, Cheung M, Gilmour K, Maimaris J, Curry J, Furmanski A, Sebire N, Halliday N, Mengrelis K, Adams S, Bernatoniene J, Bremner R, Browning M, Devlin B, Erichsen HC, Gaspar HB, Hutchison L, Ip W, Ifversen M, Leahy TR, McCarthy E, Moshous D, Neuling K, Pac M, Papadopol A, Parsley KL, Poliani L, Ricciardelli I, Sansom DM, Voor T, Worth A, Crompton T, Markert ML, Thrasher AJ., Thymus transplantation for complete DiGeorge syndrome: European experience., The Journal of allergy and clinical immunology, 140, (6), 2017, p1660-1670.e16 Journal Article, 2017 DOI

MacMahon JM, Ni Chroinin M, Hourihane J, Leahy TR., X-linked agammaglobulinaemia (XLA) presenting with neutropenia and Pseudomonas aeruginosa cellulitis., Archives of disease in childhood, 101, (12), 2016, p1106 Journal Article, 2016 DOI

Slatter M, Nademi Z, Leahy TR, Morillo-Gutierrez B, Dunn J, Barge D, Skinner R, Ryan C, Hambleton S, Abinun M, Flood T, Cant A, Gennery A., Haploidentical CD3 TCR"ß and CD19-depleted second stem cell transplant for steroid-resistant acute skin graft versus host disease., The Journal of allergy and clinical immunology, 138, (2), 2016, p603-605.e1 Journal Article, 2016 DOI

Geoghegan S, Walsh A, King MD, Lynch B, Webb D, Twomey E, Ronan Leahy T, Butler K, Gavin P., Anti-N-Methyl-D-Aspartate Receptor Antibody Mediated Neurologic Relapse Post Herpes Simplex Encephalitis: A Case Series., The Pediatric infectious disease journal, 35, (8), 2016, pe258-61 Journal Article, 2016 DOI

Leahy T.R, McManus R, Doherty D.G, Grealy R, Carr M.J, Slattery D, Ryan T, Viral Bronchiolitis is Associated with Altered Cytokine Gene Expression and Lymphocyte Activation Status, Pediatric Infectious Disease Journal, 35, (11), 2016, pp e326-e338 Journal Article, 2016 URL DOI

Traynor R, Butler KM, Cant AJ, Leahy TR., Immunodeficiency in a Child with 22q11.2 Microduplication Syndrome., Journal of clinical immunology, 36, (5), 2016, p418-419 Journal Article, 2016 DOI

Flinn AM, Cant A, Leahy TR, Butler KM, Gennery AR., Autosomal Dominant Hyper IgE Syndrome--Treatment Strategies and Clinical Outcomes., Journal of clinical immunology, 36, (2), 2016, p107-109 Journal Article, 2016 DOI

Ratjen F, Waters V, Klingel M, McDonald N, Dell S, Leahy TR, Yau Y, Grasemann H., Changes in airway inflammation during pulmonary exacerbations in patients with cystic fibrosis and primary ciliary dyskinesia., The European respiratory journal, 47, (3), 2016, p829-836 Journal Article, 2016 DOI

Duncan CJ, Mohamad SM, Young DF, Skelton AJ, Leahy TR, Munday DC, Butler KM, Morfopoulou S, Brown JR, Hubank M, Connell J, Gavin PJ, McMahon C, Dempsey E, Lynch NE, Jacques TS, Valappil M, Cant AJ, Breuer J, Engelhardt KR, Randall RE, Hambleton S., Human IFNAR2 deficiency: Lessons for antiviral immunity., Science translational medicine, 7, (307), 2015, p307ra154 Journal Article, 2015 DOI

Fitzpatrick P, Leonard J, Twomey E, Malone A, Nademi Z, Jackson M, Abinun M, Leahy TR, Gavin PJ., Severe combined immunodeficiency syndrome presenting with disseminated BCG infection., Archives of disease in childhood, 100, (9), 2015, p891 Journal Article, 2015 DOI

Yau YC, Ratjen F, Tullis E, Wilcox P, Freitag A, Chilvers M, Grasemann H, Zlosnik J, Speert D, Corey M, Stanojevic S, Matukas L, Leahy TR, Shih S, Waters V., Randomized controlled trial of biofilm antimicrobial susceptibility testing in cystic fibrosis patients., Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 14, (2), 2015, p262-266 Journal Article, 2015 DOI

Leahy TR, McManus R, Doherty DG, Grealy R, Coulter T, Smyth P, Blackshields G, Sheils O, Carr MJ, Purandare N, Geary M, Hodemaekers HM, Janssen R, Bont L, Slattery D, Ryan T, Interleukin-15 is associated with disease severity in viral bronchiolitis., 2015 Journal Article, 2015

Leahy TR, Goode M, Lynam P, Gavin PJ, Butler KM., HIV virological suppression influences response to the AS03-adjuvanted monovalent pandemic influenza A H1N1 vaccine in HIV-infected children., Influenza and other respiratory viruses, 8, (3), 2014, p360-366 Journal Article, 2014 DOI

Salem S, Langlais D, Lefebvre F, Bourque G, Bigley V, Haniffa M, Casanova JL, Burk D, Berghuis A, Butler KM, Leahy TR, Hambleton S, Gros P., Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8(K108E) mutation., Blood, 124, (12), 2014, p1894-1904 Journal Article, 2014 DOI

Kharya G, Nademi Z, Leahy TR, Dunn J, Barge D, Schulz A, Cant A, Gennery A, Slatter M., Haploidentical T-cell alpha beta receptor and CD19-depleted stem cell transplant for Wiskott-Aldrich syndrome., The Journal of allergy and clinical immunology, 134, (5), 2014, p1199-1201 Journal Article, 2014 DOI

Leahy TR, Smith OP, Bacon CL, Storey L, Lynam P, Gavin PJ, Butler KM, O'Marcaigh AS, Does vaccine dose predict response to the monovalent pandemic H1N1 influenza a vaccine in children with acute lymphoblastic leukemia? A single-centre study., 2013 Journal Article, 2013

Angulo I, Vadas O, Garçon F, Banham-Hall E, Plagnol V, Leahy TR, Baxendale H, Coulter T, Curtis J, Wu C, Blake-Palmer K, Perisic O, Smyth D, Maes M, Fiddler C, Juss J, Cilliers D, Markelj G, Chandra A, Farmer G, Kielkowska A, Clark J, Kracker S, Debré M, Picard C, Pellier I, Jabado N, Morris JA, Barcenas-Morales G, Fischer A, Stephens L, Hawkins P, Barrett JC, Abinun M, Clatworthy M, Durandy A, Doffinger R, Chilvers ER, Cant AJ, Kumararatne D, Okkenhaug K, Williams RL, Condliffe A, Nejentsev S., Phosphoinositide 3-kinase " gene mutation predisposes to respiratory infection and airway damage., Science (New York, N.Y.), 342, (6160), 2013, p866-871 Journal Article, 2013 DOI

Leahy TR, Cohen E, Allen UD., Incomplete Kawasaki disease associated with complicated Streptococcus pyogenes pneumonia: A case report., The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 23, (3), 2012, p137-139 Journal Article, 2012 DOI

Leahy TR, Yau YC, Atenafu E, Corey M, Ratjen F, Waters V., Epidemiology of borderline oxacillin-resistant Staphylococcus aureus in pediatric cystic fibrosis., Pediatric pulmonology, 46, (5), 2011, p489-496 Journal Article, 2011 DOI

Leahy TR, Punnett AS, Richardson SE, Gharabaghi F, Wadhwa A., Molecular identification of phaeohyphomycosis due to Alternaria infectoria in a patient with acute myeloid leukemia--a case report., Diagnostic microbiology and infectious disease, 66, (3), 2010, p318-321 Journal Article, 2010 DOI

Leahy TR, Malikiwi A, Cafferkey M, Butler KM., Imported childhood malaria: the Dublin experience, 1999-2006., Ir J Med Sci, 178, (3), 2009, p329-332 Journal Article, 2009 DOI

Bogue CO, Leahy TR, Rea DJ, Bitnun A, Brandao LR, Kahr WH, Jacobson S, Amaral JG, Connolly BL., Idiopathic suppurative pylephlebitis: interventional radiological diagnosis and management., Cardiovascular and interventional radiology, 32, (6), 2009, p1304-1307 Journal Article, 2009 DOI

T Leahy, D Webb, H Hoey, K Butler, Varicella Zoster Virus associated acute aseptic meningitis without exanthem in an immunocompetent 14-year-old-boy, The Pediatric Infectious Disease Journal, 27, (4), 2008, p1 - 2 Journal Article, 2008

Leahy TR, Gorman W, Murphy J, McMahon C., Haemoglobinopathy screening in an maternity hospital., Irish medical journal, 99, (6), 2006, p184-185 Journal Article, 2006 DOI

Leahy TR, Downey P, Ramsay B, Philip RK., Erythema induratum of Bazin and episcleritis in a 6 year old girl., Archives of disease in childhood, 90, (11), 2005, p1132 Journal Article, 2005 DOI

Leahy RT, Philip RK, Gibbons RJ, Fisher C, Suri M, Reardon W., Asplenia in ATR-X syndrome: a second report., American journal of medical genetics. Part A, 139, (1), 2005, p37-39 Journal Article, 2005 DOI

Non-Peer-Reviewed Publications

Adriana de Jesus, Sofia Torreggiani, Bin Lin, Jacob Mitchell, Eric Karlins, Andrew Oler, Sara Alehashemi, Dana Kahle, Katelin R Honer, Gema Souto Adeva, Eric Hanson, Gina Montealegre Sanchez, Amer Khojah, Timothy Moran, Eveline Wu, Chris Scott, Timothy Ronan Leahy, Emma Jane MacDermott, Orla Killeen, Thaschawee Arkachaisri, Zoran Gucev, Kathryn Phillippi, Vafa Mammadova, Gulnara Nasrullayeva, Raphaela Goldbach-Mansky, Splice Site Variants in IKBKG, Encoding NEMO, Detected by a Customized Analysis of Next-Generation Sequencing Data Cause an Early-onset Autoinflammatory Syndrome of Panniculitis and Cytopenias in Male and Female Patients., Arthritis and Rheumatology, ACR convergence, Virtual, Nov 5-9, 2020, 72, (S10), Wiley, 2020 Oral Presentation, 2020

Sinead Kenealy, Dina Danso-Abeam, Gareth Brady, Niamh Kerslake, Jennifer Cox, Annmarie Broderick, Emma MacDermott, Michael McDermott, Helen Lachmann, Elizabeth Ryan, Ronan Leahy, Emma M. Creagh , Identification of an NLRP6 mutation in a Paediatric Patient with Autoinflammatory Disease., ESID 2020, Birmingham (virtual), 14-17 October 2020, 2020 Oral Presentation, 2020

Elizabeth Murphy, Gearoid McGauran, David Coghlan, Ronan Leahy, Claire Purcell, Parechovirus infection as the presenting illness in an infant with SCID, Archives of Disease in Childhood, Europediatrics, Dublin, 13-15 June 2019, 104, (Suppl 3), BMJ, 2019, ppA306 - A307 Poster, 2019

Siobhan McCormack, David Orr, Fiona McNicholas, Ronan Leahy, Suzanne Kelleher, GP107 Integrated care for 22q11 deletion syndrome in ireland-meeting children's needs through enhanced care co-ordination, Archives of Disease in Childhood, Europediatrics, Dublin, 13-15 June 2019, 104, (Suppl 3), BMJ, 2019, ppA73 - A74 Poster, 2019

Jayne MacMahon, Ana Louise Hawke, Emma J MacDermott, Patrick Gavin, Karina Butler, Timothy Ronan Leahy, Orla G Killeen, P373 You give me fever!-the autoinflammatory clinic in an irish tertiary paediatric hospital, Archives of Disease in Childhood, Europediatrics, Dublin, 13-15 June 2019, 104, (Suppl 3), BMJ, 2019, ppA305 - A306 Poster, 2019

Ana Louise Hawke, Timothy Ronan Leahy, Jayne M MacMahon, Emma Jane MacDermott, Karina Butler, Patrick Gavin, Orla G Killeen, GP194 Periodic fever-the irish PFAPA story so far, Archives of Disease in Childhood, Europediatrics, Dublin, 13-15 June 2019, 104, (Suppl 3), BMJ, 2019, ppA109 - A109 Poster, 2019

Karen McCarthy, Eilis Moore, Karina Butler, Ronan Leahy, Patrick Gavin, OC29 Respiratory syncytial virus hospital admission and outcome in ireland among infants born less than 32 weeks gestation in the era of changing palivizumab prescription, Archives of Disease in Childhood, Europediatrics, Dublin, 13-15 June 2019, 104, (Suppl 3), BMJ, 2019, ppA12 - A12 Poster, 2019

Anne Lawlor, Lorna Kerin, David Orr, Ronan Leahy, Fiona Crotty, Suzanne Kelleher, Sally Lynch, Laura Duggan, Eleanor Molloy, Edel Altman, Aisling O'Dwyer, Christina Cotter, Alana Ward, Fiona Mc Nicholas, Developing integrated care in the context of rare chromosomal conditions: 22q11 Deletion Syndrome; A parent/clinician collaboration., International Journal of Integrated Care, 17, (5), Ubiquity Press, 2017 Poster, 2017

Human Herpes virus 6/7 in, editor(s)Mike Sharland, Karina Butler, Andrew Cant, Ron Dagan, Graham Davies, Ronald de Groot, David Elliman, Susanna Esposito, Adam Finn, Manolis Galanakis, Carlo Giaquinto, Jim Gray, Paul Heath, Terho Heikkinen, Ulrich Heininger, Philipp Henneke, Irja Lutsar, Hermione Lyall, Federico Martinon Torres, Andrew Pollard, Mary Ramsay, Andrew Riordan, Fernanda Rodrigues, Emmanuel Roilides, Pablo Rojo, Delane Shingadia, Steve Tomlin, and Maria Tsolia , Manual of Childhood Infections; 4th Edition, Oxford University Press, Oxford University Press, 2016, [Ronan Leahy] Book Chapter, 2016 DOI

Abdullah Al Qayoodhi, Sophie Hambleton, Andrew Hattersley, Andrew Cant, Sarah Flanagan, Karin Engelhardt, David Swan, Joseph Willet, Yaobo Xu, Mauro Koref, Ronan Leahy, Autoimmunity In STAT3 Gain Of Function Mutations; Broadening The Phenotype: P35, Clinical and Experimental Immunology, UKPIN, Liverpool, 2015, 182, 2015 Poster, 2015

G Kharya, Z Nademi, T Leahy, K Brigham, D Barge, S Hambleton, M Abinun, T Flood, A Cant, M Slatter, A Gennery, Common Gamma chain-and JAK3-deficient SCID, conditioned versus unconditioned transplant: a single centre experience, 40th Annual Meeting of the European Group for Blood and Marrow Transplantation, 40th Annual Meeting of the European Group for Blood and Marrow Transplantation, Newcastle University, 2014 Poster, 2014

T Leahy, Y Yau, F Ratjen, M Corey, V Waters, MRSA in a Pediatric CF clinic population: clinical and molecular epidemiology, risk factors for colonization, and impact on disease progression. , Pediatric Pulmonary , North American CF Conference, Orlando, Florida, 2008, 43, 2008, pp356-357 Poster, 2008

Research Expertise

Projects

  • Title
    • Mumps outbreaks in a highly vaccinated population
  • Summary
    • This is a prospective observational study using systems immunology techniques to identify serological markers that more reliably define immunity to infection with the mumps virus post vaccination
  • Funding Agency
    • NCRC
  • Date From
    • Sept 2018
  • Date To
    • June 2021
  • Title
    • Retrospective review of clinical phenotype of Autosomal recessive natural killer and glucocorticoid deficiency (AR-NKGCD aka MCM4 deficiency).
  • Summary
    • Retrospective study examining the clinical phenotype of patients with AR-NKGCD, an inborn error of immunity associated with deficiency of Natural Killer cells, increased susceptibility to viral infection and adrenocortical insufficiency
  • Date From
    • January 2021
  • Title
    • Functional exploration of a novel variant in MAPK1 associated with hypogammaglobulinemia.
  • Summary
    • Prospective observational study exploring the immunological aspects of a novel GOF mutation in MAPK1 associated with both a Noonan syndrome phenotype and a common variable immunodeficiency phenotype
  • Title
    • Functional exploration of a novel variant in BCL2L11 associated with hypogammaglobulinemia.
  • Summary
    • Prospective observational study examining the immunological basis of common variable immunodeficiency seen in a patient with a novel variant in BCL2L11.
  • Title
    • Investigation of uptake rate of antenatal Tdap vaccine in maternity hospital in Republic of Ireland and factors influencing its uptake
  • Summary
    • Prospective observational study examining factors associated with uptake of the antenatal Tdap vaccine in pregnancy in Ireland
  • Date From
    • March 2021

Keywords

IMMUNODEFICIENCY; INFECTION; PAEDIATRICS

Recognition

Representations

European Society of Immunodeficiency

European Society of Paediatric Infectious Diseases

Irish Association of Allergy and Immunology

Awards and Honours

Best Oral Research Presentation, Annual Research Day, CHI @ Crumlin 2011

Memberships

Royal College of Physicians of Ireland (Paediatrics)

European Society of Immunodeficiency

European Society of Paediatric Infectious Diseases

Irish Association of Allergy and Immunology

Professor Eleanor Molloy
Professor of Paediatrics & Child Health, Paediatrics
Professor of Paediatrics & Child Health, Trinity Inst. of Neurosciences (TCIN)

Publications and Further Research Outputs

Peer-Reviewed Publications

Hassan Eliwan and Murwan Omer and Ellen McKenna and Lynne A. Kelly and Beatrice Nolan and Irene Regan and Eleanor J. Molloy, Protein C Pathway in Paediatric and Neonatal Sepsis, Frontiers in Pediatrics, 9, 2022 Journal Article, 2022 URL DOI

Quirke FA, Healy P, Bhraonáin EN, Daly M, Biesty L, Hurley T, Walker K, Meher S, Haas DM, Bloomfield FH, Kirkham JJ, Molloy EJ, Devane D, Multi-Round compared to Real-Time Delphi for consensus in core outcome set (COS) development: a randomised trial., Trials, 2021 Journal Article, 2021

Finucane E, Biesty L, Murphy DJ, Cotter A, Molloy EJ, O"Donnell M, Treweek S, Gillespie P, Campbell M, Morrison JJ, Alvarez-Iglesias A, Gyte G, Devane D, Feasibility study protocol of a pragmatic, randomised controlled pilot trial: Membrane sweeping to prevent post-term pregnancy: The MILO Study, 2021 Journal Article, 2021

Dibble M, Ang JZ, Mariga L, Molloy EJ, Bokde ALW, Diffusion Tensor Imaging in Very Preterm, Moderate-Late Preterm and Term-Born Neonates: A Systematic Review., The Journal of pediatrics, 2021 Journal Article, 2021

Stansfield B, Molloy E, Bearer C, In search of a unifying diagnosis., Pediatric research, 2021 Journal Article, 2021

Twohig A, Murphy JF, McCarthy A, Segurado R, Underdown A, Smyke A, McNicholas F, Molloy EJ, The preterm infant-parent programme for attachment-PIPPA Study: a randomised controlled trial., Pediatric research, 2021 Journal Article, 2021

Quirke FA, Healy P, Bhraonáin EN, Daly M, Biesty L, Hurley T, Walker K, Meher S, Haas DM, Bloomfield FH, Kirkham JJ, Molloy EJ, Devane D, COHESION: core outcomes in neonatal encephalopathy (protocol)., Trials, 2021 Journal Article, 2021

Zareen Z, Strickland T, Fallah L, McEneaney V, Kelly L, McDonald D, Molloy EJ., Cytokine dysregulation in children with cerebral palsy, Developmental Medicine & Child Neurology, 2020 Journal Article, 2020

Eleanor J. Molloy, The Doctor"s Dilemma: lessons from GB Shaw in a modern pandemic COVID-19, Pediatric Research, 2020 Journal Article, 2020

Whitla L, Devins M, Molloy EJ, Twomey M, O'Reilly M, Balfe J, Children's Palliative Care; the identified Learning Needs of Paediatricians., Irish medical journal, 2020 Journal Article, 2020

Eleanor Molloy, Zunera Zareen, Tammy Strickland, Victoria Eneaney, Lynne Kelly, Denise McDonald, Deirdre Sweetman, Cytokine Dysregulation Persists in Childhood Post Neonatal Encephalopathy, 2020 Journal Article, 2020

Eleanor J. Molloy, Anna Lavizzari, Claus Klingenberg, Jochen Profit, John A. F. Zupancic, Alexis S. Davis, Fabio Mosca, Cynthia F. Bearer, Charles C. Roehr, Neonates in the COVID-19 pandemic, Pediatric Research, 2020 Journal Article, 2020

Ryan E, Bolger T, Barrett MJ, Blackburn C, Okafor I, McNamara R, Molloy EJ, Paediatric Head Injury and Traumatic Brain Injury., Irish medical journal, 2020 Journal Article, 2020

Dean Huggard, Lynne Kelly, Emer Ryan, Fiona McGrane, Niamh Lagan, Edna Roche, Joanne Balfe, T. Ronan Leahy, Orla Franklin, Derek G. Doherty, Eleanor J. Molloy, Increased systemic inflammation in children with Down syndrome, Cytokine, 127, 2020, p154938 Journal Article, 2020 TARA - Full Text DOI

O'Dea M, Sweetman D, Bonifacio SL, El-Dib M, Austin T, Molloy EJ, Management of Multi Organ Dysfunction in Neonatal Encephalopathy., Frontiers in pediatrics, 2020 Journal Article, 2020

Dietrick B, Molloy E, Massaro AN, Strickland T, Zhu J, Slevin M, Donoghue V, Sweetman D, Kelly L, O'Dea M, McGowan M, Vezina G, Glass P, Vaidya D, Everett AD, Plasma and Cerebrospinal Fluid Candidate Biomarkers of Neonatal Encephalopathy Severity and Neurodevelopmental Outcomes., The Journal of pediatrics, 2020 Journal Article, 2020

Eleanor J. Molloy, James L. Wynn, Joseph Bliss, Joyce M. Koenig, Fleur M. Keij, Matt McGovern, Helmut Kuester, Mark A. Turner, Eric Giannoni, Jan Mazela, Marina Degtyaeva, Tobias Strunk, Sinno H. P. Simons, Jan Janota, Franz B. Plotz, Ages van den Hoogen, Willem de Boode, Luregn J. Schlapbach, Irwin K. M. Reiss, Neonatal sepsis: need for consensus definition, collaboration and core outcomes, Pediatric Research, 2020 Journal Article, 2020

Lavizzari A, Klingenberg C, Profit J, Zupancic JAF, Davis AS, Mosca F, Molloy EJ, Roehr CC, International Neonatal COVID-19 Consortium, International comparison of guidelines for managing neonates at the early phase of the SARS-CoV-2 pandemic., Pediatric research, 2020 Journal Article, 2020

Allen J, Brenner M, Hauer J, Molloy E, McDonald D , Severe Neurological Impairment: A delphi consensus-based definition, European Journal of Pediatric Neurology, 2020 Journal Article, 2020 DOI

Finucane E, Biesty L, Murphy DJ, Cotter A, Molloy EJ, O"Donnell M, Treweek S, Gillespie P, Campbell M, Morrison JJ, Alvarez-Iglesias A, Gyte G, Devane D, Feasibility study protocol of a pragmatic, randomised controlled pilot trial: Membrane sweeping to prevent post-term pregnancy: The MILO Study, 2020 Journal Article, 2020

Molloy EJ, Strunk T, Role of C-Reactive Protein for Late-Onset Neonatal Sepsis., JAMA pediatrics, 2020 Journal Article, 2020

Eleanor J. Molloy, Cynthia F. Bearer, COVID-19 in children and altered inflammatory responses, Pediatric Research, 2020 Journal Article, 2020

Dean Huggard, Eleanor J Molloy, Question 1: Palivizumab for all children with Down syndrome?, Archives of Disease in Childhood, 2019, parchdischild--2018--316140 Journal Article, 2019

Bearer CF, Chalak L, Fuentes-Afflick E, Molloy EJ, The rewards of peer-reviewing., Pediatric research, 2019 Journal Article, 2019

Molloy EJ, Dr Janusz Korczak: paediatrician, children's advocate and hero., Pediatric research, 2019 Journal Article, 2019

Chalak L, Ferriero DM, Gressens P, Molloy E, Bearer C, A 20 years conundrum of neonatal encephalopathy and hypoxic ischemic encephalopathy: are we closer to a consensus guideline?, Pediatric research, 2019 Journal Article, 2019

John Allen, Eleanor Molloy, Denise McDonald, Severe neurological impairment: a review of the definition, Developmental Medicine & Child Neurology, 2019 Journal Article, 2019

Alsaffar M, Balfe J, McGrane F, Nadeem M, et al, Coeliac disease in children with Down syndrome in Ireland, Archives of Disease in Childhood, (doi: 10.1136/), 2019 Journal Article, 2019 DOI

Dibble, M. and O'Dea, M.I. and Hurley, T. and Byrne, A. and Colleran, G. and Molloy, E.J. and Bokde, A.L.W., Diffusion tensor imaging in neonatal encephalopathy: A systematic review, Archives of Disease in Childhood: Fetal and Neonatal Edition, 105, (5), 2019, p480 - 488 Journal Article, 2019 DOI

Bearer C, Agostoni C, Anand KJS, Ambalavanan N, Bhandari V, Bliss JM, Bloomfield F, Bonifacio SL, Buhimschi I, Cilio MR, Coppes M, Czinn SJ, Molloy E, Toward the elimination of bias in Pediatric Research., Pediatric research, 2019 Journal Article, 2019

Kiva Brennan, Bobby D. O'Leary, Danielle Mc Laughlin, David Kinlen, Eleanor J. Molloy, Declan Cody, Sri Paran, Fionnuala M. McAuliffe, Andrew E. Hogan, Sarah L. Doyle, Nucleic acid cytokine responses in obese children and infants of obese mothers, Cytokine, 119, 2019, p152--158 Journal Article, 2019

Saima Aslam, Tammy Strickland, Eleanor J. Molloy, Neonatal Encephalopathy: Need for Recognition of Multiple Etiologies for Optimal Management, Frontiers in Pediatrics, 7, 2019 Journal Article, 2019

Eleanor J. Molloy, Cynthia F. Bearer, Insights in Pediatric Research, Pediatric Research, 2019 Journal Article, 2019

O'Driscoll DN, McGovern M, Greene CM, Molloy EJ, Gender Disparities in Preterm Neonatal Outcomes., Acta Paediatrica, (May), 2018, pePub ahead- Journal Article, 2018

Geraghty AA, O'Brien EC, Alberdi G, Horan MK, Donnelly J, Larkin E, Segurado R, Mehegan J, Molloy EJ, McAuliffe FM, Maternal protein intake during pregnancy is associated with child growth up to 5 years of age, but not through insulin-like growth factor-1: findings from the ROLO study., The British journal of nutrition, 2018 Journal Article, 2018

EJ Molloy, N Modi, Developing Core Outcome Set for Women's , Newbron and Child Health: the crown initiative, Pedatric Research, 2018 Journal Article, 2018

EJ Molloy, C Bearer, Neonatal encephalopathy versus Hypoxic-Ischemic Encephalopathy, Paediatric Research, 2018 Journal Article, 2018 DOI

J Alexander, N Bholahm N Okigo, R Devlin, A Betts, J Healy, S Higgins, J Meehan, EJ Molloy, Fifteen minute consultation: infant with a small head, Irish Paediatric Association, Galway, December 2018, 2018 Conference Paper, 2018

Huggard D, McGrane F, Lagan N, Roche E, Balfe J, Leahy TR, Franklin O, Moreno A, Melo AM, Doherty DG, Molloy EJ, Altered endotoxin responsiveness in healthy children with Down syndrome., BMC immunology, 2018 Journal Article, 2018 TARA - Full Text DOI

Bearer CF, Molloy EJ, Pediatric research: brief update on key objectives., Pediatric research, 2018 Journal Article, 2018

Onwuneme C, Molloy EJ, Vitamin D intake for preterm infants: how much do they really need?, Archives of disease in childhood, 2018 Journal Article, 2018

Molloy EJ, Beaer C, Neonatal encephalopathy versus Hypoxic-Ischemic Encephalopathy., Pediatric research, 2018 Journal Article, 2018

Kiva Brennan, Bobby D. O"Leary, Danielle Mc Laughlin, Eamon P. Breen, Emma Connolly, Nusrat Ali, David N. O"Driscoll, Ema Ozaki, Rebecca Mahony, Kelly Mulfaul, Aoife M. Ryan, Aine Ni Chianain, Alison McHugh, Eleanor J. Molloy, Andrew E. Hogan, Sri Paran, Fionnuala M. McAuliffe, Sarah L. Doyle, Type 1 IFN Induction by Cytosolic Nucleic Acid Is Intact in Neonatal Mononuclear Cells, Contrasting Starkly with Neonatal Hyporesponsiveness to TLR Ligation Due to Independence from Endosome-Mediated IRF3 Activation, The Journal of Immunology, 2018, pji1700956 Journal Article, 2018

Jean Donnelly, Perinatal Inflammation and Childhood Adiposity- A gender effect?, Journal of Maternal and Fetal Neonatal Medicine, 2018, p1 - 8 Journal Article, 2018 DOI

CF Bearer, EJ Molloy, Gender bias at Pedictric Reserch?, Pediatric Research, 2018 Journal Article, 2018 DOI

AA Geraghty, E O'Brien,lberdi, MK Horan, J Donnelly, E Larkin, R Segurado, J mehegan E Molloy, FM McAuliffe, Maternal protein intake during pregnancy is associated with child growth u to 5 years of age, but not through insulin-like growth factor-1: findings from the ROLO study, British Journal of Nutrition, 120, (11), 2018, p1252 - 1261 Journal Article, 2018

K Brennan, R O'Leary, D McLaughlin, E Connelly, N Ali, D O'Driscoll, EJ Molloy et al, Harnessing proficiencies in Type-1-Interferon induction downstream of cytosolic nucleic acid sensors in neonates and infancts for development of paediatric vaccines, Journl of Immunology, 2018 Journal Article, 2018

E Boyle, D Chay, C Corrigan,J Scanlon, A Tahir, AP Worrall,K Zavin, EJ Molloy, MA Healy, A review of hypernatraemic dehydration management in OLCHC in comparson to a selection of international guidelines, Irish Paediatric Association, Galway, December 2018, 2018 Conference Paper, 2018

EJ Molloy, S Mader, N Modi et al, Parent, child and public involvement in child health reserch: core value not just an optional extra, Pediatric Reserch, Epub ahead of print, 2018 Journal Article, 2018 DOI

D Huggard, EJ Molloy, Do children with Down syndrome benefit from extra vaccinations?, Archives of Disease in Childhood, 2018 Journal Article, 2018

SM Wuinlan, N Roldriguez-Alvarez, EJ Molloy, SF Madden, GB Byllan, DC Henshall, EM Jimenez-Mateos, Behaviral, lectrophic and histpathologicall effects of phenobarbital in a mouse model of neonatal hypoxi-induced seizures, Scientific Reports, 2018 Journal Article, 2018

McGovern M, Flynn L, Coyne S, Molloy EJ, Does coagulase negative staphylococcal sepsis cause neurodevelopmental delay in preterm infants?, Archives of disease in childhood, 2018 Journal Article, 2018

C Onwuneme, EJ Molloy, Vitamin D intake for preterm infants: How much do they really need?, Archives of Dseases in Childhood, 2018 Journal Article, 2018

Molloy EJ, Gale C, Marsh M, Bearer CF, Devane D, Modi N, Developing core outcome set for women's, newborn, and child health: the CROWN Initiative., Pediatric research, 2018 Journal Article, 2018

M McGovern, L Fynn, S Coyne, EJ Molloy, Doees coagulase negative staphylococcal sepsis cause neurodeveopmental delay in preterm infants?, Archive of Disease in Childhood, 2018 Journal Article, 2018 DOI

K Burke, A Ennes, M Hays, A Mayfield, M Rya, M Winfield, J Meehan, EJ Molloy, The New Sepsis Three guidelines and their appliabiity to paediatric medicin, Irish Paediatric Association , Galway, December 2018, 2018 Conference Paper, 2018

M Alsaffar, J Balfe, S Quinn, N Gadelsayd, EJ Molloy, Coeliac Dseae in Children with Down Syndrome in Ireland, Archives of Disease in Childhood, 2018 Journal Article, 2018 URL

D Huggard, EJ Molloy, Pavilizumab for all children with Down syndrome?, Archives of Disease in Childhood, 2018 Journal Article, 2018

J Donnelly, EJ Molloy, F McAuliffe, Perinatal Inflammation and Childhood Adiposty - A Gender Effect?, Journal of maternal-Feta & Neonatal Medicine, 2018 Journal Article, 2018

Quinlan SMM, Rodriguez-Alvarez N, Molloy EJ, Madden SF, Boylan GB, Henshall DC, Jimenez-Mateos EM, Complex spectrum of phenobarbital effects in a mouse model of neonatal hypoxia-induced seizures., Scientific reports, 2018 Journal Article, 2018

, Sharing Progress in Neonatal (SPIN) Brain, Gut, Heart, and Lung., Neonatology, 2017 Journal Article, 2017

, Introduction-Standing on each other's shoulders., Pediatric research, 2017 Journal Article, 2017

Molloy EJ, Modi N, Greenough A, Lagercrantz H, Bearer CF, Turner M., The future of pediatric research: European perspective., Pediatric research, 81, (1-2), 2017, p138-139 Journal Article, 2017 DOI

, Immune function? A missing link in the gender disparity in preterm neonatal outcomes., Expert review of clinical immunology, 2017 Journal Article, 2017

Murwan Omer, Eleanor J Molloy, QUESTION 2: Is permissive hypercapnia beneficial to preterm infants?: Table 1, Archives of Disease in Childhood, 2017, parchdischild--2016--312050 Journal Article, 2017

Sweetman DU, Onwuneme C, Watson WR, Murphy JF, Molloy EJ., Perinatal Asphyxia and Erythropoietin and VEGF: Serial Serum and Cerebrospinal Fluid Responses., Neonatology, 111, (3), 2017, p253-259 Journal Article, 2017 DOI

Ehrich J, Molloy E, Kerbl R, Pettoello-Mantovani M, Gerber-Grote A., Conceptual Design of Future Children's Hospitals in Europe. The Role of Public and Private Stakeholders as Transferors of New Concepts from Theory into Practice., The Journal of pediatrics, 183, 2017, p204-205 Journal Article, 2017 DOI

, Serial cytokine alterations and abnormal neuroimaging in newborn infants with encephalopathy., Acta paediatrica (Oslo, Norway : 1992), 2017 Journal Article, 2017

Ehrich J, Molloy E, Kerbl R, Pettoello-Mantovani M, Vural M, Gerber-Grote A., Conceptual Design of Future Children's Hospitals in Europe: The Role of Caregivers in Transferring New Concepts from Theory into Practice., The Journal of pediatrics, 184, 2017, p244-245.e1 Journal Article, 2017 DOI

Ehrich J, Molloy E, Pettoello-Mantovani M., Conceptual Design of Future Children's Hospitals in Europe: Planning, Building, Merging, and Closing Hospitals., The Journal of pediatrics, 182, 2017, p411-412.e1 Journal Article, 2017 DOI

, Expression of X-linked Toll-like receptor 4 signaling genes in female vs. male neonates., Pediatric research, 2017 Journal Article, 2017

Cowman J, Quinn N, Geoghegan S, Müllers S, Oglesby I, Byrne B, Somers M, Ralph A, Voisin B, Ricco AJ, Molloy EJ, Kenny D., Dynamic platelet function on von Willebrand factor is different in preterm neonates and full-term neonates: changes in neonatal platelet function., Journal of thrombosis and haemostasis : JTH, 14, (10), 2016, p2027-2035 Journal Article, 2016 DOI

Peter Cosgrove, Eleanor J Molloy, QUESTION 2: Is frusemide necessary following red cell transfusion in preterm neonates?, Archives of Disease in Childhood, 101, (9), 2016, p868--870 Journal Article, 2016

Sweetman DU, Onwuneme C, Watson WR, O'Neill A, Murphy JF, Molloy EJ., Renal function and novel urinary biomarkers in infants with neonatal encephalopathy., Acta Paediatr, 105, (11), 2016, pe513-e519 Journal Article, 2016 DOI

Twohig A, Reulbach U, Figuerdo R, McCarthy A, McNicholas F, Molloy EJ., SUPPORTING PRETERM INFANT ATTACHMENT AND SOCIOEMOTIONAL DEVELOPMENT IN THE NEONATAL INTENSIVE CARE UNIT: STAFF PERCEPTIONS., Infant mental health journal, 37, (2), 2016, p160-171 Journal Article, 2016 DOI

Geurtzen R, van Heijst AF, Babarao S, Molloy E, Draaisma JM, Hogeveen M, Practices in antenatal counselling for extremely premature infants amongst European trainees., 2016 Journal Article, 2016

EL Molloy, Cutting edge: How to translate research into clinical practice., Neonatal discussion Form, Wales, UK, 2015 Invited Talk, 2015

Aslam S, Molloy EJ, Biomrkers of multiorgan injury in neonatal encephalopthy., Biomarkers in Medicine, 9, (3), 2015, p267 - 275 Journal Article, 2015

Donnelly JM, Lindsay KL, Walsh JM, Horan M, Molloy EJ, McAuliffe FM, Fetal metabolic influences of neonatal anthropometry and adiposity., BMC pediatrics, 15, 2015, p175 Journal Article, 2015

O'Hare FM, Watson RWG, O'Neill A, Donoghue V, O'Donnell C, Murphy JFM, Twomey A, Molloy EJ, Neutrophil and Monocyte Toll-Like Receptor 4, CD11b and Reactive Oxygen Intermediates and Neuroimaging Outcomes in Preterm Infants., Pediatric Research, In Press, 2015 Journal Article, 2015

Geoghegan S, Nicholson AJ, Molloy EJ, Incorporating Teaching in Global Child Health into Irish Medical School Curriculum., 2015 Journal Article, 2015

Chike Onwuneme, Aoife Carroll, Dermot Doherty, Heike Bruell, Ricardo Segurado, Mark Kilbane, Nuala Murphy, Malachi J. McKenna, Eleanor J. Molloy, Inadequate vitamin D levels are associated with culture positive sepsis and poor outcomes in paediatric intensive care, Acta Paediatr, 104, (10), 2015, pe433--e438 Journal Article, 2015

Onwuneme C, Blanco A, O'Neill A, Watson B, Molloy EJ, Vitamin D enhances reactive oxygen intermediates production in phagocytic cells in term and preterm infants., Pediatric research, 2015 Journal Article, 2015

Onwuneme C, Diya B, Uduma O, McCarthy RA, Murphy N, Kilbane MT, McKenna MJ, Molloy EJ, Correction of vitamin D deficiency in a cohort of newborn infants using daily 200 IU vitamin D supplementation., 2015 Journal Article, 2015

Eliwan HO, O'Hare FM, Watson WR, O'Neill A, Molloy EJ, Neonatal Brain Injury and Systemic Inflammation: Modulatin by Activated Protein c ex vivo, Clinical Exp Immunology, 179, (3), 2015, p477 - 484 Journal Article, 2015 DOI

Chike Onwuneme, Fidelma Martin, Roberta McCarthy, Aoife Carroll, Ricardo Segurado, John Murphy, Anne Twomey, Nuala Murphy, Mark Kilbane, Malachi McKenna, Eleanor Molloy, The Association of Vitamin D Status with Acute Respiratory Morbidity in Preterm Infants, The Journal of Pediatrics, 166, (5), 2015, p1175--1180.e1 Journal Article, 2015

Cynthia F. Bearer, Eleanor J. Molloy, Expanding research, relevance, and reach, Pediatr Res, 79, (1-1), 2015, p2--2 Journal Article, 2015

Rebolledo J, ;Igoe D, O'Donnell J, Domegan L, Boland M, Freyne B, McNamara A, Molloy EJ, Callaghan M, Ryan A O'Flanagan D, Influenza in hospitalized children in Ireland in the pandemic period and the 2010/2011 season: risk factors for paediatric intensive-care-unit admission, Epidemiolo Infect, 11, (1-10), 2014, pEpub ahead of print Journal Article, 2014

O'Hare FM, Watson RWG, O'Neill A, Donoghue V, O'Donnell C, Murphy JFM, Twomey A, Molloy EJ, Persistent Systemic Monocyte and Neutrophil Activation in Neonatal Encephalopathy, Journal of Maternal-Fetal & Neonatal Medicine, In Press, 2014 Journal Article, 2014

Horan M, Gibney E, Molloy E, McAuliffe F, Methodologies to assess paediatric adiposity, Irish Medical Science, May 4, 2014, pEpub ahead of print Journal Article, 2014

Geoghegan S, Vavasseur C, Donoghue V, Molloy EJ, Easily missed, potentially fatal complication in an extremely preterm infant, British Medical Journal, In Press, (Case Reports), 2014 Journal Article, 2014

Freyne B, Stafford A, Knowles S, O'Hora A, Molloy E, Perinatal Treponema pallidum: evidence based guidelines to reduce mother to child transmission., 2014 Journal Article, 2014

Waters A, Jennings K, Fitzpatrick E, Coughlan S, Molloy EJ, et all, Incidence of congenital cytomegalovirus infrection in Ireland: Implications for screeing and diagnosis, Journal of Clinical Virology, Jan 3, (pii: S1386-6532(13)6), 2014 Journal Article, 2014

EL Molloy, Diagnostic evaluation of neonates with early onset sepsis., Recent Advances in Neonatal Medicine , Wurzburg, Germany, 2014 Invited Talk, 2014

EL Molloy, The Neonate and the Neutrophil, Spring North Yorkshire Neonatal Discussion Forum, North Yourkshire, UK, 2014, 2014 Invited Talk, 2014

Chukwu J, Cunney R, Molloy EJ, Congenital Diaphragmatic Hernia Surveillance, Irish Medical Journal, 107, (8), 2014, p261- Journal Article, 2014

Lutomski JE, Shiely F, ;Molloy EJ, The prevalence of syphilis at childbirth in Ireland: A six-year review, Journal of Maternaty and Fetal Neonatal Medicine, Dec 20, 2014, pEpub ahead of print Journal Article, 2014

Eleanor Molloy, TRAIN study: TRAnsfusion In Neonates and ideal red cell volume study, http://isrctn.org/>, 2014 Journal Article, 2014

EL Molloy, The development of the preterm neonatal immun e system and new evidence on the role of vitamin D, Satellite symposium on the ongoing global Challenge of RSV infection: emerging interventions against RSV. 32nd Annual Meeting of the European Society for Paediatric Infectious Diseases , Dublin, 2014 Invited Talk, 2014

Carroll A, Onwuneme C, McKenna MJ, Mayne PD, Molloy EJ, Murphy NP, Vitamin D Status in Irish Children and Adolescents: Value of Fortification and Supplementation, Clinical Pediatrics (Phila), July 7, (pii: 000992281454199), 2014, pEpub ahead of print Journal Article, 2014

Donnelly JM, Walsh JM, Byrne J, Molloy EJ, McAuliffe Fm, Impact of maternal diet on neonatal anthropometry: a randomized controlled trial, Pediatric and Obestricts, Jan 20, (doi:10.1111/j.2047-2), 2014, pEpub ahead of print Journal Article, 2014

Molloy EJ, Riordan M, Sweetman DU, Management of renal dysfunction following term perinatal hypoxia-ischaemia., 2013 Journal Article, 2013

Eliwan HO, O'Hare FM, Sweetman D, Watson WR, MolloyEJ, Elevated Toll-like Receptor Expression in Neonatal Encephalopathy: Immunomodulation by Activated Protein C, Pediatric Academic Societies , Washington DC, USA, 2013, 2013 Meeting Abstract, 2013

Molloy EJ, O'Hare FM, William Watson R, Toll-like receptors in Neonatal Sepsis., 2013 Journal Article, 2013

Freyne B, Knowles S, Molloy EJ, Treponema pallidum: The role of a dedicated infectious mother to chidl transmission, Irish Medical Journal, 2013 Journal Article, 2013

Sweetman D, Molloy EJ, Renal Biomarkers and Neonatal encephalopathy, Eur J Pediatr, 172, (3), 2013, p305 - 316 Journal Article, 2013

Waters A, Jennings K, Fitzpatrick E, Coughlan S, Molloy E, De Gascun CF, Hall WW, Prevalence of Congenital CMV infection in Ireland: Implications for routine screening and diagnosis., 15th Annual Meeting of the European Society for clincial Virology (ESCV) and Joint Meeting with the European Society for Veterinary Virology (ESVV), 2013, 2013 Meeting Abstract, 2013

Eleanor Molloy, Preterm Infant Parent Programme for Attachment (PIPPA study), http://isrctn.org/>, 2013 Journal Article, 2013

McCarthy LK, Molloy EJ, Twomey AR, Murphy JFA, O'Donnell CPF, A Randomized Trial of Single Nasal Prong or Face Mask for Respiratory Support for Preterm Infants in the Delivery Room (ISRCTN59061709), Pediatric Academic Societies , Washington DC, USA, 2013, 2013 Meeting Abstract, 2013

Donnelly J, Horan M, Walsh J, McGowan C, Byrne J, Molloy EJ, McAuliffe F, Perinatal inflammation and increase neonatal adiposity, Irish Society of Immunology, Dublin, 2013, 2013 Meeting Abstract, 2013

McCarthy LK, Molloy EJ, Twomey AR, Murphy JFA, O'Donnell CPF, Randomised Trial of Polyethylene Bag andExothermic Mattress or Polyethylene Bag Alone for Thermoregulation in Preterm Infants in the Delivery Room, Pediatric Academic Societies, Washington DC, USA, 2013, 2013 Meeting Abstract, 2013

Lutomski J, Dempsey E, Molloy E, An epidemiological study of factors associated with preterm infant in-hospital mortality., 2013 Journal Article, 2013

McKenna M, Kilbane M, Molloy Ej, Vitamin D in 2011: the treat to target concept is impirtant., Irish Medical Journal , April, 2013, pContent ID=4057 Journal Article, 2013

O'Hare FmM, Watson RWG, O'Neill A, Donoghue V, O'Donnell C, Murphy JFM, Twomey A, Molloy EJ, Innate Immune Dysregulation in Severe Neonatal Brain Injury, Irish Society of Immunology, Dublin, 2013, 2013 Meeting Abstract, 2013

Eliwan HO, O'Hare F, Sweetmand D, Watson RWG, O'Neill A, Molloy EJ, Neonatal Encephalopathy and Systemic Inflammation: Modulation by Activated Protein C, Irish Society of Immunology, Dublin, 2013, 2013 Meeting Abstract, 2013

Freyne B, Knowles S, Molloy EJ, Universal Perinatal Screening for Treponema pallidum: the role of a dedicated infectios diseses team for prevention of mother to chile transmission, Journal Sexually Transmitted Diseases, 2013 Journal Article, 2013

McCarthy LK, Twomey AR, Molloy EJ, Murphy JFA, O'Donnell CPF, A Randomized trial of Single nasal prong or facemask for Respiratory support for Preterm infancts in the Delivery Room (ISRCTN59061709), Pediatrics, 132, (2), 2013, pe389 - e395 Journal Article, 2013

Twohig A, McNicholas F, Molloy EJ, Prespectives on Attachment of Infants in Neonatal Intensive Care: An Analysis of Staff Preceptions, Pediatric Academic Societies, Washington DC, USA, 2013, 2013 Meeting Abstract, 2013

Onwuneme C, Clancy N, Molloy EJ, Vitamin D and Paediatric immune function, Journal of Maternaty and Fetal Neonatal Medicine, 26, (7), 2013, p639 - 646 Journal Article, 2013

Sweetman D, Olloy EJ, Management of Renal dysfunction and Neonatal encephalopathy , Acta Paediatricia, 102, (3), 2013, p233 - 241 Journal Article, 2013

Sweetman DU, Ng YS, Donoghue V, Grant T, Molloy EJ, Coagulation Abnormalities and Grade of Encephalopathy in Term Perinatal Hypoxia-Ischaemia, Pediatric Academic Societies, Washington DC, USA, 2013, ppE-PAS2013:3800.55 Meeting Abstract, 2013

Farrington A, Onwuneme C, Mollogy EJ, Is there a correlation between Vitamin D Levels and clincal markers in preterm infants?, Pediatric Academic Societies , Washington DC, USA, 2013, 2013 Meeting Abstract, 2013

Donnelly J, Horan M, Walsh J, McGowan C, Byrne J, Molloy EJ, McAuliffe F, Impact of a low GI diet on neonatal Body Composition (ROLO Kids), Pediatric Academic Societies , Washington DC, USA, 2013, 2013 Meeting Abstract, 2013

O'Hare FM, Watson RWG, Molloy EJ, Toll-Like receptors in Neonatal responses to bacteria, Acta Paediatrica, 102, (6), 2013, p572 - 578 Journal Article, 2013

Onwuneme C, Doherty D, Healy M, Kilbane M, Murphy N, McKenna MJ, Molloy EJ, Vitamin D in Paediatric Intensive Care Patients at Risk of Sepsis, Pediatric Academic Societies , Washington DC, USA, 2013, 2013, ppE-PAS2013:2912.135 Meeting Abstract, 2013

Sweetman DU, Molloy EJ, Biomarkers of acute kidney injury in neonatal encephalopathy., 2013 Journal Article, 2013

Onwuneme C, Blance A, Watson RWG, O'Neill A, Murphy N, Mollogy EJ, Vitamin D Increases Phagocytic Function In Preterm Infants, Irish Society of Immunology, Dublin, 2013, 2013 Meeting Abstract, 2013

McCarthy LK, Molloy EJ, Twomey AR, Murphy JF> O'Donnell CP, A randomised Trial of Exothermic Mattersses for Preterm Newborns in Polyethylene Bags,, Pediatrics, 132, (1), 2013, pe135 - e141 Journal Article, 2013

McCarthy LK, Molloy EJ, Murphy JF, O'Donnell CP, Twomey AR, A randomized trial of nasal prong or face mask for respiratory support for preterm newborns., 2013 Journal Article, 2013

Walsh H, O'Reilly M, Molloy EJ, Neonatal Palliative Care survey in Irish Nurseries, Irish Medical Journal, 1063, (2), 2013, p60 - 61 Journal Article, 2013

Roche-Lydon M, Molloy EJ, Dempsey E, Epidemiologic study of Intensive care factors in the Preterm infant, Irish Medical Journal, 106, (1), 2013, p9 - 12 Journal Article, 2013

Walsh H, Molloy E, Neonatal palliative care., 2013 Journal Article, 2013

Molloy EJ, The decline and fall of the Cardiac biomarker: a good indicator of resolution of cardiac dysfunction after perinatal saphyxia, Neonatology (Invited Editorial), 102, (4), 2012, p249 - 250 Journal Article, 2012

Molloy EJ, Olatundun Owoeye C, Knowles S, Is antenatal screening for syphilis still necessary?, Irish Medical Journal, 105, (2), 2012, p37 - 38 Journal Article, 2012

McCarthy RA, McKenna MJ, Oyefeso O, Uduma O, Murray BF, Brady JJ, Kilbane MT, Murphy JF, Twomey A, Donnell CP, Murphy NP, Molloy EJ, Vitamin D nutritional status in preterm infants and response to supplementation., The British journal of nutrition, 2012, p1-8 Journal Article, 2012

Sweetman D, Armstrong K, Murphy J, Molloy EJ, Cardiac biomarkers in neonatal hypoxic ischaemia, Acta Paediatrica, 101, (4), 2012, p338 - 343 Journal Article, 2012

Parameshwar M, Abuy I, Knowles S, Molloy EJ, Neonatal Meningitis: a diagnostic dilema, Irish Medical Journal, 105, (8), 2012, p284 Journal Article, 2012

Armstrong K, Franklin O, Molloy EJ, Sweetman D, Cardiovascular dysfunction in infants with neonatal encephalopathy., 2012 Journal Article, 2012

Kieran E, Twomey A, Molloy EJ, Murphy J O'Donnell C, Randomised Trial of Prongs or Mask for Nasal Continuous Postive Airway Pressure in Preterm Infants, Pediatrics, 103, (5), 2012, pe1170 - e1176 Journal Article, 2012

Harrison G, Degascun C,l Boyle M, Knowles S, Molloy EJ, Seen but not Heard, Congenital Cytomegalovirus, Arch Dis Child Fetal Neonatal Ed, 97, (5), 2012, pF390 Journal Article, 2012

Noone D, Kieran E, Molloy EJ, Magnesium homeostasis: Paradoxically Stable in Extremely Low Birth Weight (ELBW) Infants, Neonatology, 101, (4), 2012, p274 - 277 Journal Article, 2012

Carroll A, Kilbane M, McCarthy R, McKenna M, Molloy EJ, Murphy N, Onwuneme C, Towards evidence based medicine for paediatricians. Question 2. What is the ideal dose of vitamin D supplementation for term neonates?, 2012 Journal Article, 2012

Onwuneme C, Murphy N, McCarthy R, Carroll A, Molloy EJ, the correnct dose of Vitamin D Supplementation interm infants, Arch Dis Child, 97, (4), 2012, p387 - 389 Journal Article, 2012

Freyne B, O'Hare FM, MOlloy EJ, Efficacy and safety of intravenous Ig and alterations in hamatological parameters of infants with isoimmune haemolytic disease, Arch Dis Child Fetal Neonatal Edition, 97, (1), 2012, pF76 - F77 Journal Article, 2012

Eleanor Molloy, Congenital Diaphragmatic Hernia - Prenatal to Childhood Management and Outcomes, 2012 Journal Article, 2012

Molloy EJ, The decline and fall of the cardiac biomarker: a good indicator of resolution of cardiac dysfunction following perinatal asphyxia. commentary on D.C. Vijlbrief et al.: Cardiac biomarkers as indicators of hemodynamic adaptation during postasphyxial hypothermia treatment (Neonatology 2012;102:243-248)., 2012 Journal Article, 2012

Noone D, Kieran E, Molloy EJ, Serum magnesium in the first week of life in extremely low birth weight infants., 2012 Journal Article, 2012

Velagapudi A, McCarthy R, Oyefeso O, Molloy EJ, Vitamin D deficiency is associated with altered haematological indices in VEry Low Birth Weight Infants, Journal of Paediatrics, 158, (4), 2011, p687 Journal Article, 2011

Bahari M, Prunty N, Molloy EJ, Parents' attitude toward Infant Safety during Air travel, Archive of Disease in Childhood, 96, (7), 2011, p701 Journal Article, 2011

, 163: Is chorionicity an independent risk factor for adverse neurological outcome in very low birth weight (VLBW) twins?, 2011 Journal Article, 2011

Armstrong Km,Franklin O, Molloy EJ, The 10 rules of an MD, British Medical Journal Careers, (Careers), 2011, pid=20003562 Journal Article, 2011

El-Khuffash AF, McNamara PJ, Molloy EJ, Slevin M, Troponin T, N-terminal pro natriuretic peptide and a patent ductus arteriosus scoring system predict death before discharge or neurodevelopmental outcome at 2 years in preterm infants., 2011 Journal Article, 2011

Armstrong K, Franklin O, Molloy EJ, Neonatal encephalopathy and Cardiovascular Dysfunction, Archive of Disease in Childhood, Jul 27, 2011, pEpub ahead of print Journal Article, 2011

, Immune System of the Newborn, 2011 Journal Article, 2011

Morgan CT, Culliton M, McCarthy R, Molloy EJ, Non-blood group-specific red blood cell transfusions in preterm infants and necrotizing enterocolitis, Journal of Pediatrics, Nov 12, 2011, pEpub ahead of print Journal Article, 2011

ElL-Khuffash A, Slevin M,. McNamara PJ, Molloy EJ, Troponin T, N-Terrminal Pro Natriuretic Peptide, and a patent ductus arteriosus scoring system predict neurodevelopmental outcome at 2 years or death before discharge in preterm Infants, Archive of Disease in Childhood, 96, (2), 2011, pF133 - F137 Journal Article, 2011

McKenna MJ, McCarthy R, Brady J, Murray B, Molloy EJ, Vitamin D Nutrient Intake for All Life Stages, Irish Medical Journal, 104, (4), 2011, p102 Journal Article, 2011

EL-Khuffash A, Kieran E, Molloy EJ, Neonatal Respiratory Extracorporeal Membrane Oxdygenation (ECMO) support in Ireland, Irish Medical Journal, 104, (3), 2011, p78 - 81 Journal Article, 2011

, Fluid and Electrolyte Balance in the Newborn, 2011 Journal Article, 2011

Connell J, De Gascun C, Hall WW, Hassan J, Kissoon G, Knowles S, Molloy E, Waters A, Human cytomegalovirus UL144 is associated with viremia and infant development sequelae in congenital infection., 2010 Journal Article, 2010

Ahearne C, Molloy EJ, Phototherapy and exchange transfusion mayh confound the association of NEC and IVIG, Pediatrics, Feb, 2010, peletters/125/1/139 Journal Article, 2010

Low E, Healy M, Molloy EJ, Neonatal albumin infusions in paediatric intensive care., 2010 Journal Article, 2010

El-Khuffash A, Molloy EJ, Incidental finding of endocarditis in a preterm neonate., 2009 Journal Article, 2009

, Triggering Receptor Expressed on Myeloid Cells (TREM) Family and the Application of Its Antagonists, 2009 Journal Article, 2009

McCarthy R, McCallion N, Harrison G, Molloy EJ, Relationship between vitamin D and alkaline phosphatase in very-low-birthweight infants., 2009 Journal Article, 2009

Molloy EJ, Triggering Receptor Expressed on Myeloid Cells (TREM) family and the application of its antagonists., 2009 Journal Article, 2009

Molloy EJ, Walsh S, Towards evidence based medicine for paediatricians. Is intravenous immunoglobulin superior to exchange transfusion in the management of hyperbilirubinaemia in term neonates?, 2009 Journal Article, 2009

Molloy EJ, El-Khuffash A, Bieda A, Jelinek MM, Baley J, Elevated iron indices in preterm infants: association with male gender., 2009 Journal Article, 2009

El-Khuffash A, Molloy E, The Use of N-Terminal-Pro-BNP in Preterm Infants., 2009 Journal Article, 2009

Barrett MJ, Molloy EJ, Do we neglect infant safety during air travel?, 2009 Journal Article, 2009

McNamara R, Molloy EJ, Rationalising the use of "growing bloods" in stable preterm infants., 2008 Journal Article, 2008

Morris I, Molloy EJ, Albumin administration in the management of neonatal hypoalbuminaemia., 2008 Journal Article, 2008

El-Khuffash A, Davis PG, Walsh K, Molloy EJ, Cardiac troponin T and N-terminal-pro-B type natriuretic peptide reflect myocardial function in preterm infants., 2008 Journal Article, 2008

El-Khuffash AF, Molloy EJ, Walsh K, Left atrial appendage mimicking an intra-cardiac vegetation in preterm neonates., 2008 Journal Article, 2008

El-Khuffash AF, Molloy EJ, Influence of a patent ductus arteriosus on cardiac troponin T levels in preterm infants., 2008 Journal Article, 2008

O'Rourke DJ, El-Khuffash A, Moody C, Walsh K, Molloy EJ, Patent ductus arteriosus evaluation by serial echocardiography in preterm infants., 2008 Journal Article, 2008

El-Khuffash A, Barry D, Walsh K, Davis PG, Molloy EJ, Biochemical markers may identify preterm infants with a patent ductus arteriosus at high risk of death or severe intraventricular haemorrhage., 2008 Journal Article, 2008

, Left Atrial Appendage Mimicking an Intra-Cardiac Vegetation in Preterm Neonates, 2008 Journal Article, 2008

, Heliox for prevention of morbidity and mortality in ventilated newborn infants, 2008 Journal Article, 2008

El-Khuffash AF, Molloy EJ, Serum troponin in neonatal intensive care., 2008 Journal Article, 2008

Morris I, McCallion N, El-Khuffash A, Molloy EJ, Serum albumin and mortality in very low birth weight infants., 2008 Journal Article, 2008

, Quantitative Assessment of the Degree of Ductal Steal Using Celiac Artery Blood Flow to Left Ventricular Output Ratio in Preterm Infants, 2008 Journal Article, 2008

El-Khuffash A, Higgins M, Molloy EJ, Walsh K, Quantitative assessment of the degree of ductal steal using celiac artery blood flow to left ventricular output ratio in preterm infants., 2008 Journal Article, 2008

Molloy E, Are elevated peripheral leukocytes markers of septic etiology in asphyxiated infants with neurological disability?, 2008 Journal Article, 2008

, Serum Troponin in Neonatal Intensive Care, 2008 Journal Article, 2008

McHale S, Thomas M, Hayden E, Bergin K, McCallion N, Molloy EJ, Variation in inspiratory time and tidal volume with T-piece neonatal resuscitator: association with operator experience and distraction., 2008 Journal Article, 2008

Amoruso M, Culliton M, El-Khuffash AF, Molloy EJ, N-terminal pro-B-type natriuretic peptide as a marker of ductal haemodynamic significance in preterm infants: a prospective observational study., 2007 Journal Article, 2007

El-Khuffash A, Molloy EJ, Are B-type natriuretic peptide (BNP) and N-terminal-pro-BNP useful in neonates?, 2007 Journal Article, 2007

Molloy EJ, Possible sequelae of sustained lung inflation in resuscitation of preterm infants., 2007 Journal Article, 2007

Fitzpatrick JM, Grantham-Sloan JJ, Molloy EJ, O'Neill AJ, Sheridan-Pereira M, Watson RW, Webb DW, Neonatal encephalopathy is associated with altered perinatal systemic neutrophil apoptosis., 2007 Journal Article, 2007

El-Khuffash A, Molloy EJ, Incidental finding of endocarditis in a preterm neonate., 2007 Journal Article, 2007

Doyle BT, Fitzpatrick JM, Grantham JJ, Molloy EJ, O'Neill AJ, Sheridan-Pereira M, Taylor CT, Watson RW, Webb DW, Effects of heat shock and hypoxia on neonatal neutrophil lipopolysaccharide responses: altered apoptosis, Toll-like receptor-4 and CD11b expression compared with adults., 2006 Journal Article, 2006

Molloy EJ, O'Neill SM, Neonatal Escherichia coli sepsis: possible effects of gender, type of surfactant, or time to initiation of antibiotics?, 2006 Journal Article, 2006

Molloy EJ, Deakins K, Are carbon dioxide detectors useful in neonates?, 2006 Journal Article, 2006

Di Fiore JM, Martin RJ, Molloy EJ, Does gastroesophageal reflux cause apnea in preterm infants?, 2005 Journal Article, 2005

, Performance of an Automated Immature Granulocyte Count as a Predictor of Neonatal Sepsis, 2005 Journal Article, 2005

, Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor Have Differential Effects on Neonatal and Adult Neutrophil Survival and Function, 2005 Journal Article, 2005

Molloy EJ, Nigro KG, O'Riordan M, Sandhaus LM, Walsh MC, Performance of an automated immature granulocyte count as a predictor of neonatal sepsis., 2005 Journal Article, 2005

Fitzpatrick JM, Grantham JJ, Molloy EJ, O'Neill AJ, Sheridan-Pereira M, Watson RW, Webb DW, Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor have differential effects on neonatal and adult neutrophil survival and function., 2005 Journal Article, 2005

Eleanor Molloy, Michelle Walsh, Response, J Perinatol, 25, (5), 2005, p360--360 Journal Article, 2005

Fitzpatrick JM, Grantham JJ, Molloy EJ, O'Neill AJ, Sheridan-Pereira M, Watson RW, Webb DW, Labor promotes neonatal neutrophil survival and lipopolysaccharide responsiveness., 2004 Journal Article, 2004

Doyle BT, Fitzpatrick JM, Greenan MC, Molloy E, O'Neill AJ, Phelan D, Watson C, Watson RW, Gene expression profile of inflammatory neutrophils: alterations in the inhibitors of apoptosis proteins during spontaneous and delayed apoptosis., 2004 Journal Article, 2004

, Labor Promotes Neonatal Neutrophil Survival and Lipopolysaccharide Responsiveness, 2004 Journal Article, 2004

Molloy EJ, Increasing infant safety in air travel: deficiencies are not limited to child restraint systems., 2004 Journal Article, 2004

Doctor BA, Molloy EJ, Reed MD, Walsh MC, Perinatal toxicity of domestic naphthalene exposure., 2004 Journal Article, 2004

Fitzpatrick JM, Grantham JJ, Molloy EJ, O'neill AJ, Sheridan-Pereira M, Watson RW, Webb DW, Labor induces a maternal inflammatory response syndrome., 2004 Journal Article, 2004

Fitzpatrick JM, Grantham JJ, Molloy EJ, O'Neill AJ, Sheridan-Pereira M, Watson RW, Webb DW, Sex-specific alterations in neutrophil apoptosis: the role of estradiol and progesterone., 2003 Journal Article, 2003

Research Expertise

Description

Our research group aims to delineate perinatal and early neonatal inflammatory responses in health and disease. We have established longitudinal cohorts of infants with neonatal encephalopathy and preterm infants as well as neonatal controls in order to explore the role of early inflammatory changes and developmental outcomes. We have studied the role of activated monocytes and neutrophils in neonatal diseases and the use of immunomodulatory agents such as vitamin d and activated protein c.

Keywords

1,25-DIHYDROXYVITAMIN-D3