Professor Martina Hennessy

Professor Martina Hennessy

Director of Intern Education

Assoc Prof Consultant Medical Education, Pharmacology & Therapeutics


Publications and Further Research Outputs

  • R Woods, T Subramaniam, A Patterson, M Hennessy, C Timon, Validation and evaluation of new assessments for the otolaryngology undergraduate medical clerkship., The Journal of Laryngology and Otology, 2015, p1 - 6Journal Article, 2015, URL
  • Morris MC, Hennessy M, Conlon KC, Ridgway PF., Evaluation of a "Subintern" Role: Action Over Observation For Final-Year Medical Students in Surgery., J Surg Educ, 72, (5), 2015, p862 - 867Journal Article, 2015, DOI
  • Patterson, M., Sharek, D., Hennessy, M., Phillips, M., and Schofield S., Medical humanities: A closer look at learning, Medical Humanities, 42, (2), 2016, p115 - 120Journal Article, 2016
  • Song,G.; Hennessy,M.; Zhao,Y.L.; Li,Q.; Han,W.D.; Qi,Y.; Zhao,W.N.; Silke,B.; Barry,M.; Doyle,R.; Spiers,J.P., Adrenoceptor blockade alters plasma gelatinase activity in patients with heart failure and MMP-9 promoter activity in a human cell line (ECV304), Pharmacological Research, 54, 2006, p57 - 64Journal Article, 2006
  • Song,G.; Hennessy,M.; Zhao,Y.L.; Li,Q.; Han,W.D.; Qi,Y.; Zhao,W.N.; Silke,B.; Barry,M.; Doyle,R.; Spiers,J.P., Adrenoceptor blockade alters plasma gelatinase activity in patients with heart failure and MMP-9 promoter activity in a human cell line (ECV304), Pharmacological Research, 54, 2006, p57 - 64Journal Article, 2006
  • Spiers,J.P.; Kelso,E.J.; Fong,S.; Edge,G.; Song,G.; McDermott,B.J.; Hennessy,M., Alterations in vascular matrix metalloproteinase due to ageing and chronic hypertension: effects of endothelin receptor blockade, Journal of Hypertension, 23, 2005, p1717 - 1724Journal Article, 2005
  • Spiers,J.P.; Kelso,E.J.; Fong,S.; Edge,G.; Song,G.; McDermott,B.J.; Hennessy,M., Alterations in vascular matrix metalloproteinase due to ageing and chronic hypertension: effects of endothelin receptor blockade, Journal of Hypertension, 23, 2005, p1717 - 1724Journal Article, 2005
  • Donohoe C.L, Conneely J.B, Zilbert N, Hennessy M, Schofield S, Reynolds J.V, Docemur Docemus: Peer-Assisted Learning Improves the Knowledge Gain of Tutors in the Highest Quartile of Achievement but Not Those in the Lowest Quartile, Journal of Surgical Education, 72, (6), 2015, p1139 - 1144Journal Article, 2015, DOI , URL
  • Orikiiriza J, Nakawesi J, Kikaire B, Turitwenka D, Schlech W, Kambugu A, Lamorde M, Normark J, Hennessy M, Musiime V, Rujumba J, Ndeezi G, Tumwesigye NM, Doherty DG, Achan J, Unmet needs persist in pediatric HIV programs: lessons from selected case studies in Uganda. , AIDS , 31, 2017, p1196 - 1199Journal Article, 2017, DOI
  • , Push and stay factors affecting Irish medical student migration intentions., Irish journal of medical science, 2017Journal Article, 2017
  • Gouda, P., Kitt, K., Evans, D.S., Goggin, D., McGrath, D., Last, J., Hennessy, M., Arnett, R., O"Flynn, S., Dunne, F., O"Donovan, D., Irish medical students" understanding of the intern year, Irish Medical Journal, 109, (4), 2016Journal Article, 2016
  • , Investigating the Irish brain drain: factors influencing migration intentions among medical students., BMC proceedings, 2015Journal Article, 2015
  • Gouda, P., Kitt, K., Evans, D.S., Goggin, D., McGrath, D., Last, J., Hennessy, M., Arnett, R., O'Flynn, S., Dunne, F., O'Donovan, D., Ireland's medical brain drain: Migration intentions of Irish medical students, Human Resources for Health, 13, (1), 2015Journal Article, 2015
  • , Medical students' views on selection tools for medical school--a mixed methods study., Irish medical journal, 2014Journal Article, 2014
  • Morris, M.C., Gillis, A.E., Smoothey, C.O., Hennessy, M., Conlon, K.C., Ridgway, P.F., An alternative certification examination ("ACE") in surgery, Journal of Surgical Education, 71, (6), 2014, p779-789Journal Article, 2014
  • Stevens, L., Kelly, M.E., Hennessy, M., Last, J., Dunne, F., O"Flynn, S., Medical students views on selection tools for medical school " A mixed methods study, Irish Medical Journal, 107, (8), 2014Journal Article, 2014
  • , Pro forma: impact on communication skills?, The clinical teacher, 2013Journal Article, 2013
  • Burke E, Teeling M, Hennessy M, Introduction of an academic Internship in Ireland: views of undergraduate medical students, Irish Journal of Medical Science, 2018Journal Article, 2018, DOI
  • Delaney H., Devane D., Hennessy M., Parker A., Murphy L., Cronin P., Smith V. , Limited evidence exists on the effectiveness of education and training interventions on trial recruitment; a systematic review, Journal of Clinical Epidemiology, 113, 2019, p75 - 82Journal Article, 2019, DOI
  • O"Shea MP, Harkin K, Sulaiman HM, Hennessy M, Barry M, Kennedy C., More Teaching Not More Exams: Interns Views in Improving Prescribing Safety, Irish medical journal, 112, (5), 2019, p943Journal Article, 2019, DOI
  • M. Hennessy, D. Kelleher, J. P. Spiers, M. Barry, P. Kavanagh, D. Back, F. Mulcahy and J. Feely, St Johns wort increases expression of P-glycoprotein: implications for drug interactions, British Journal of Clinical Pharmacology, 53, (1), 2002, p75-82Journal Article, 2002, DOI , TARA - Full Text
  • Carthy, P., O'Domhnaill, A., O'Mahony. M., Broderick, B.M., Hennessy, M., Donnelly, A., Naughton, O. and Lyons, S, Local NO2 concentrations and asthma among over-50s in Ireland: a microdata analysis, International Journal of Epidemiology , 49, (6), 2020, p1899 - 1908Journal Article, 2020, DOI , TARA - Full Text
  • Sheill G., Hennessy M., O'Neill L., Reynolds S., Towns J., Gill M., Guinan E., Exercise and chronic health conditions in the community: A qualitative Study of Patients and Fitness instructors, Health and Social Care in the Community, 2021Journal Article, 2021, DOI
  • Burke, E., HEennessy, M, Evaluation of an early career clinical academic training programme using the CIPP model, BMJ Open , 11, (11), 2021Journal Article, 2021, URL
  • Sheill G., Hennessy M., Devenney K., Reynolds S., Towns J., Gill M., Guinan E., A hospital to community exercise referral pathway: results of a pilot project., Irish Journal of Medical Science., 2022Journal Article, 2022
  • Hennessy, M.; Spiers, J.P., A primer on the mechanics of P-glycoprotein the multi drug transporter, Pharmacological Research, 55, 2007, p1 - 15Journal Article, 2007
  • Hennessy, M.; Spiers, J.P., A primer on the mechanics of P-glycoprotein the multi drug transporter, Pharmacological Research, 55, 2007, p1 - 15Journal Article, 2007
  • Phillips M, Pilkington R, Patterson A, Hennessy M, Death and dignity through fresh eyes., The clinical teacher, 8, (4), 2011, p241-244Journal Article, 2011, DOI
  • Rietz, A. Volkov, Y. Davies, A. Hennessy, M. Spiers, J., Okadaic acid induces MMP-9 expression in fibroblast: Crosstalk between protein phosphatase inhibition and β-adrenoceptor signalling, British Journal of Pharmacology, 165, 2012, p274 - 288Journal Article, 2012
  • Rietz, A. Volkov, Y. Davies, A. Hennessy, M. Spiers, J., Okadaic acid induces MMP-9 expression in fibroblast: Crosstalk between protein phosphatase inhibition and β-adrenoceptor signalling, British Journal of Pharmacology, 165, 2012, p274 - 288Journal Article, 2012
  • Kennedy A, Hennessy M, Bergin C, Mulcahy F, Hopkins S, Spiers JP, Ribavirin and interferon alter MMP-9 abundance in vitro and in HIV-HCV-coinfected patients., Antiviral therapy, 16, (8), 2011, p1237-47Journal Article, 2011
  • Abulhul E, McDonald K, Martos R, Phelan D, Spiers JP, Hennessy M, Baugh J, Watson C, O'Loughlin C, Ledwidge M, Long-Term Statin Therapy in Patients With Systolic Heart Failure and Normal Cholesterol: Effects on Elevated Serum Markers of Collagen Turnover, Inflammation, and B-Type Natriuretic Peptide., Clinical Therapeutics, 34, (1), 2012, p91 - 100Journal Article, 2012
  • Abulhul E, McDonald K, Martos R, Phelan D, Spiers JP, Hennessy M, Baugh J, Watson C, O'Loughlin C, Ledwidge M, Long-Term Statin Therapy in Patients With Systolic Heart Failure and Normal Cholesterol: Effects on Elevated Serum Markers of Collagen Turnover, Inflammation, and B-Type Natriuretic Peptide., Clinical Therapeutics, 34, (1), 2012, p91 - 100Journal Article, 2012
  • Svärd J, Spiers JP, Mulcahy F, Hennessy M, Nuclear receptor-mediated induction of CYP450 by antiretrovirals: functional consequences of NR1I2 (PXR) polymorphisms and differential prevalence in whites and sub-Saharan Africans., Journal of acquired immune deficiency syndromes (1999), 55, (5), 2010, p536-49Journal Article, 2010
  • McMahon CJ, Hennessy M, Boyle G, Feely J, Meaney JF, Prevalence of renal artery stenosis in flash pulmonary oedema: determination using gadolinium-enhanced MRA., European journal of internal medicine, 21, (5), 2010, p424-8Journal Article, 2010
  • Hennessy M, Clarke S, Spiers JP, Kelleher D, Mulcahy F, Hoggard P, Back D, Barry M, Intracellular accumulation of nelfinavir and its relationship to P-glycoprotein expression and function in HIV-infected patients., Antiviral therapy, 9, (1), 2004, p115-22Journal Article, 2004
  • Hennessy M, Clarke S, Spiers JP, Mulcahy F, Kelleher D, Meadon E, Maher B, Bergin C, Khoo S, Tjia J, Hoggard P, Back D, Barry M, Intracellular indinavir pharmacokinetics in HIV-infected patients: comparison with plasma pharmacokinetics., Antiviral therapy, 8, (3), 2003, p191-8Journal Article, 2003
  • Molloy D, Molloy A, O'Loughlin C, Falconer M, Hennessy M, Inappropriate use of proton pump inhibitors., Irish journal of medical science, 179, (1), 2010, p73-5Journal Article, 2010
  • Hopkins S, Lambourne J, Farrell G, McCullagh L, Hennessy M, Clarke S, Mulcahy F, Bergin C, Role of individualization of hepatitis C virus (HCV) therapy duration in HIV/HCV-coinfected individuals., HIV medicine, 7, (4), 2006, p248-54Journal Article, 2006
  • Mahmud A, Hennessy M, Feely J, Effect of sildenafil on blood pressure and arterial wave reflection in treated hypertensive men., Journal of human hypertension, 15, (10), 2001, p707-13Journal Article, 2001
  • Merry C, Barry MG, Ryan M, Tjia JF, Hennessy M, Eagling VA, Mulcahy F, Back DJ, Interaction of sildenafil and indinavir when co-administered to HIV-positive patients., AIDS (London, England), 13, (15), 1999, pF101-7Journal Article, 1999
  • Kennedy, A. Doherty , D.G Petrasca, A. Hennessy, M. Spiers, J.P., HIV-1 Tat clade-specific cytokine induction in monocytes/macrophages is not evidenced in total or Vγ9Vδ2 T lymphocytes, AIDS, 28, 2014, p131 - 133Journal Article, 2014, DOI
  • Morris M, Donohoe G, Hennessy M, O Ciardha C, Pro forma: impact on communication skills?, The clinical teacher, 10, (5), 2013, p318-22Journal Article, 2013
  • M Phillips, M Hennessy, A Patterson, Power and its Applications: a new module in the medical curriculum at Trinity College Dublin, Medical Humanities, 2013Journal Article, 2013
  • Kennedy A, Petrasca A, Doherty DG, Hennessy M, Spiers JP, HIV-1 Tat clade-specific cytokine induction in monocytes/macrophages is not evidenced in total or V"9V"2 T lymphocytes., AIDS (London, England), 28, (1), 2014, p131-3Journal Article, 2014, URL
  • Svärd J, Blanco F, Nevin D, Fayne D, Mulcahy F, Hennessy M, Spiers JP, Differential interactions of antiretroviral agents with LXR, ER and GR nuclear receptors: potential contributing factors to adverse events., British journal of pharmacology, 171, (2), 2014, p480-97Journal Article, 2014
  • Morris MC, Gillis AE, Smoothey CO, Hennessy M, Conlon KC, Ridgway PF, An Alternative Certification Examination ("ACE") in Surgery., Journal of surgical education, 2014, p779-789Journal Article, 2014, DOI , TARA - Full Text
  • Woods R, Ramasubbu B, Donohoe C, Hennessy M, Near-peer bedside clinical teaching: example of a successful programme., The clinical teacher, 11, (6), 2014, p472-7Journal Article, 2014
  • Laragh Stevens, Maureen Kelly, Martina Hennessy, Jason Last, Fidelma Dunne, Siun O'Flynn , Medical Student Views on Selection Tools for Medicine- A mixed methods study. Accepted by Irish Medical Journal , Irish medical Journal , 2014, p229 - 231Journal Article, 2014
  • O' Flynn S, Power Susan, Hennessy M, Mills A, Lapthorne S. , 'Guidance Counsellors perspectives on revised entry and selection mechanisms to medicine and the HPAT', Institute of Guidance Counsellors, 2013, - 7-10Protocol or guideline, 2013
  • Hennessy , Quinn, Annual Report: Development Studies Association of Ireland , Trinity College Dublin , 2014Report, 2014
  • HPAT Research group , National research group evaluating revised entry mechanisms to medicine, IUA/ CDFMSI, 2013, 24 ppReport, 2013
  • Hennessy M, Barry M, Drug interactions of clinical significance. , Irish Medical Times , 1999Journal Article, 1999
  • Hennessy M, Feely J. , Understanding Drug Interactions. , Modern Medicine in Ireland , 1998Journal Article, 1998
  • Uduma, Hennessy , Building Research Capacity in Higher Education Institutes through Partnerships with African Universities, Trinity College Dublin , November , 2012Report
  • Uduma, Hennessy , A Report on North South Experiences of Doctoral Training for Development in Africa, Trinity College dublin , November , 2012Report
  • Martina Hennessy, Dawn Quinn , TIDI Impact report , Trinity College Dublin , July , 2014Report
  • Martina Hennessy, Dawn Quinn, TIDI Impact Report , Trinity College Dublin , July , 2013Report
  • Feely J, Hennessy M, Sheehan O, 'Hypertension and Health a Patient Guide. ', Dept of Clinical Pharmacology and therapeutics , 2000, -Protocol or guideline

Research Expertise

  • Title
    Proposal for the establishment of a Medication Safety Team for St James's Hospital, Dublin
    Summary
    Funding Agency
    HSE
    Date From
    2003
    Date To
    Ongoing
  • Title
    NOURISH :development of an irish-Ugandan HIV/ Nutrition research cluster Irish Aid / HEA
    Summary
    Funding Agency
    Irish Aid / Hea
    Date From
    2012
    Date To
    2016
  • Title
    Nourish extension project
    Summary
    to build on previous nourish work b supporting the PhD students in the early post doctoral phase
    Funding Agency
    HEA/ Irish AID
    Date From
    2018
    Date To
    2020
  • Title
    Establishment of a Dublin HIV Cohort Database
    Summary
    Funding Agency
    HRB
    Date From
    2005
    Date To
    2010
  • Title
    Role of the nuclear receptors (PXR and CAR) and thymidine kinase polymorphisms on the pharmacodynamics and pharmacokinetics of antiretroviral therapy in HIV disease
    Summary
    Funding Agency
    European Clinical Aids Society
    Date From
    2006
    Date To
    2010
  • Title
    Proposal to Expand and consolidate the Development Studies Association of Ireland in collaboration with TIDI
    Summary
    Funding Agency
    Irish Aid
    Date From
    2012
    Date To
    2016
  • Title
    Development of an e-repository of integrative case studies
    Summary
    Funding Agency
    Trinity College Dublin
    Date From
    2008
    Date To
    2010
  • Title
    Medicine 2 Research - Led teaching in Medicine
    Summary
    Thematic priority Research Led Teaching
    Funding Agency
    MEDINE 2 Network for Medical Education in Europe
    Date From
    2009
    Date To
    2012
  • Title
    Doctoral training for Development in Africa
    Summary
    Funding Agency
    irish Aid/ HEA
    Date From
    2008
    Date To
    2014
  • Title
    Curricular Reform of Medical Education in ireland
    Summary
    Non Peer Reviewed HEA funding for curricular reform and development of Academic Clinician Posts
    Funding Agency
    HEA
    Date From
    2007
    Date To
    2014
  • Title
    Effect of ß-Adrenoceptor Antagonism on Plasma Matrix Metalloproteinase Activity and Oxidative State in Stable Heart Failure.
    Summary
    Funding Agency
    Baggot Street Fund
    Date From
    2001
    Date To
    2004
  • Title
    Development of interactive web based Continual assessment for pharmacology
    Summary
    Funding Agency
    Trinity College
    Date From
    2005
    Date To
    2007

Health Care & Health Services (including Health Technology and Health Information Systems), Other Basic Medicine, Immunity and Infection (including Rheumatology & Inflammatory disease), Pharmacology & Toxicology including drug formulation and delivery, Other Clinical Medicine, Other Clinical Medicine, Health Care & Health Services (including Health Technology and Health Information Systems), Pharmacology & Toxicology including drug formulation and delivery, Other Clinical Medicine, Cardiovascular& Related Disease, Health Care & Health Services (including Health Technology and Health Information Systems), Immunity and Infection (including Rheumatology & Inflammatory disease), Cardiovascular& Related Disease, Other Basic Medicine, Cardiovascular& Related Disease, Pharmacology & Toxicology including drug formulation and delivery, Other Basic Medicine, Immunity and Infection (including Rheumatology & Inflammatory disease),

Recognition

  • Professors prize in Paediatrics 1994
  • Glaxo-Wellcome Oral communications Prize British Pharmacological Society, Jan 2000 The Pharmacokinetics of Nelfinavir Administered Twice Versus Three Times Daily in HIV positive Patients. 2000
  • Glaxo-Wellcome CPS Oral Communications Prize British Pharmacological Society, 2001. The role of the multi-drug transporter P-glycoprotein in HIV disease 2001
  • Bristol Myers Squibb Travel Scholarship Award British HIV Association, April 2001 The Clinical Implications of P-glycoprotein Expression and Function in HIV Positive Patients. 2001
  • 1st honours Medical Jurisprudence 5th medical year. 1993
  • Distinction in Pharmacology 3rd medical year. 1992
  • Overall honours 2nd and 3rd medical years combined 1992
  • The Irish Association of Pharmacologists Oral communications prize, Nov 2000 A Role for P glycoprotein Expression and Function in Drug Interactions with St John's Wort. 2000
  • Society for Sexually Transmitted Diseases in Ireland Oral communications Prize April 2000. The Clinical Implications of Intracellular Protease Inhibitor Concentrations in HIV Patients. 2000
  • Royal Academy of Medicine in Ireland Registrars prize (2nd) April 2001 The Role of P-glycoprotein Expression and Function in HIV Positive Patients. 2001
  • UCL Teaching Award, Royal Free and University College Medical School Academic 2006
  • British HIV Association 2008
  • Development Studies Association of Ireland present
  • London Clinical Pharmacology group 2010
  • Eurolife Network of Universities present
  • British Pharmacological Society present
  • Fellow Royal college of Physicians in Ireland present
  • Fellow Royal college of Physicians London present
  • British Hypertension society initially as a student present
  • Internship oversight committee - representing the Trinity Network of Interns (123) 2011 - present
  • Member,Education sub-committee Medical Council representing University 2009- present
  • Member. Patient Safety committee Tallaght Hospital 2013-present
  • HEA Clinical Skills development advisory group 2008-2009
  • Member European Academic alliance in Global Health 2010- present
  • Chair,Medication safety committee St James's Hospital 2011-present
  • member of Eurolife International health committee representing university 2008-present
  • Member Board of Governance of Clinical Research Facility ST James's Hospital 2013-present
  • HEA Clinical Skills development advisory group 2008-2009
  • Member. Patient Safety committee Tallaght Hospital 2013-present
  • member of Eurolife International health committee representing university 2008-present
  • Member European Academic alliance in Global Health 2010- present
  • Irish University Medical School Consortium 2011- present
  • Member European Academic alliance in Global Health 2010- present
  • member of Eurolife International health committee representing university 2008-present
  • Member Board of Governance of Clinical Research Facility ST James's Hospital 2013-present
  • Internship oversight committee - representing the Trinity Network of Interns (123) 2011 - present
  • Irish University Medical School Consortium 2011- present
  • HEA Clinical Skills development advisory group 2008-2009
  • Chair,Medication safety committee St James's Hospital 2011-present
  • Member,Education sub-committee Medical Council representing University 2009- present
  • Irish University Medical School Consortium 2011- present
  • Member Board of Governance of Clinical Research Facility ST James's Hospital 2013-present
  • Chair,Medication safety committee St James's Hospital 2011-present
  • Internship oversight committee - representing the Trinity Network of Interns (123) 2011 - present
  • Member,Education sub-committee Medical Council representing University 2009- present
  • Member. Patient Safety committee Tallaght Hospital 2013-present