Dr Emer Guinan

Dr Emer Guinan

Principle Investigator


Emer is an Assistant Professor in the School of Medicine with responsibility for the Interprofessional Learning programme for the Faculty of Health Sciences. Her main research interest is in the role of exercise and physical activity in ameliorating treatment side effects and optimising survivorship for patients with cancer. Her work considers both the therapeutic and the physiological impact of exercise programmes. She has a particular interest in the role of exercise for patients with complex cancer presentations including patients with cancer of the gastrointestinal tract and those with advanced disease. She's been awarded >€1.7 million in research funding as either principle investigator or co-applicant from external peer-reviewed grants (Health Research Board, Irish Cancer Society, Medical Charities Research Group), external research bursaries (Irish Society of Chartered Physiotherapists) and internal competitions from the Faculty of Health Sciences, Trinity College. Emer has published over 50 peer reviewed publications and 1 book chapter. In addition, she has lead an interprofessional learning research programme across the Faculty of Health Sciences.

I am an Assistant Professor in the School of Medicine with responsibility for the Interprofessional Learning programme for the Faculty of Health Sciences. My main research interest is in the role of exercise and physical activity in ameliorating treatment side effects and optimising survivorship for patients with cancer. My work considers both the therapeutic and the physiological impact of exercise programmes. I have a particular interest in the role of exercise for patients with complex cancer presentations including patients with cancer of the gastrointestinal tract and those with advanced disease. I have been awarded >€1.7 million in research funding as either principle investigator or co-applicant from external peer-reviewed grants (Health Research Board, Irish Cancer Society, Medical Charities Research Group), external research bursaries (Irish Society of Chartered Physiotherapists) and internal competitions from the Faculty of Health Sciences, Trinity College. I have published over 50 peer reviewed publications and 1 book chapter. In addition, I lead an interprofessional learning research programme across the Faculty of Health Sciences.

Publications and Further Research Outputs

  • Moran J, Murphy A, Murphy D, Austin A, Moran D, Cronin C, Guinan E, Hussey J, The energy expenditure of non-weight bearing crutch walking on the level and ascending stairs., Gait & posture, 42, (1), 2015, p23-6Journal Article, 2015, DOI
  • Moran J., Guinan E., McCormick P., Larkin J., Mockler D., Hussey J., Moriarty J., Wilson F., The ability of prehabilitation to influence postoperative outcome after intra-abdominal operation: A systematic review and meta-analysis, Surgery (United States), 160, (5), 2016, p1189-1201Journal Article, 2016, DOI
  • Guinan, E.M., Doyle, S.L., O'Neill, L., Dunne, M.R., Foley, E.K., O'Sullivan, J., Reynolds, J.V., Hussey, J., Effects of a multimodal rehabilitation programme on inflammation and oxidative stress in oesophageal cancer survivors: the ReStOre feasibility study, Supportive Care in Cancer, 25, (3), 2016, p749 - 756Journal Article, 2016, DOI
  • Moran, J., Wilson, F., Guinan, E., McCormick, P., Hussey, J., Moriarty, J., Role of cardiopulmonary exercise testing as a risk-assessment method in patients undergoing intra-abdominal surgery: A systematic review, British Journal of Anaesthesia, 116, (2), 2016, p177-191Journal Article, 2016, DOI , TARA - Full Text
  • Guinan, E.M., Dowds, J., Donohoe, C., Reynolds, J.V., Hussey, J., The physiotherapist and the esophageal cancer patient: From prehabilitation to rehabilitation, Diseases of the Esophagus, 30, (1), 2017, p1-12Journal Article, 2017, DOI
  • Moran, J., Wilson, F., Guinan, E., McCormick, P., Hussey, J., Moriarty, J., The preoperative use of field tests of exercise tolerance to predict postoperative outcome in intra-abdominal surgery: a systematic review, Journal of Clinical Anesthesia, 35, 2016, p446-455Journal Article, 2016, DOI
  • Elliott, J.A., Docherty, N.G., Eckhardt, H.-G., Doyle, S.L., Guinan, E.M., Ravi, N., Reynolds, J.V., Roux, C.W.L., Weight Loss, Satiety, and the Postprandial Gut Hormone Response After Esophagectomy: A Prospective Study, Annals of Surgery, 266, (1), 2016, p82 - 90Journal Article, 2016, DOI , TARA - Full Text
  • Cahir, C., Guinan, E., Dombrowski, S.U., Sharp, L., Bennett, K., Identifying the determinants of adjuvant hormonal therapy medication taking behaviour in women with stages I-III breast cancer: A systematic review and meta-analysis, Patient Education and Counseling, 98, (12), 2015, p1524-1539Journal Article, 2015, TARA - Full Text
  • Guinan, E.M., Doyle, S.L., Bennett, A.E., O'Neill, L, Gannon, J., Elliott, J.A., O'Sullivan, J., Reynolds, J.V., & Hussey, J., Sarcopenia during neoadjuvant therapy for oesophageal cancer: characterising the impact on muscle strength and physical performance, Supportive Care in Cancer, 26, (5), 2018, p1569 - 1576Journal Article, 2018, DOI , URL
  • Sheill G, Guinan E, Neill LO, Hevey D, Hussey J, The views of patients with metastatic prostate cancer towards physical activity: a qualitative exploration, Supportive Care in Cancer, 26, (6), 2017, p1747 - 1754Journal Article, 2017, DOI
  • Valkenet K., Trappenburg T., Ruurda J., Guinan E., Reynolds J.V., Nafteux P., Fontaine M., Rodrigo E., van det Peet D., Hania S., Sosef M., Willms J., Rosman C., Pieters H., Scheepers J., Faber T., Kouwenhoven E., Tinselboer M., Rasanen J., Ryynanen H., Fosselink R., van Hillegersberg R., Backx F. , 'Preoperative inspiratory muscle training in patients undergoing esophagectomy: the results of the PREPARE trial, an international multicenter RCT, British Journal of Surgery, 105, (5), 2018, p502 - 511Journal Article, 2018, URL
  • O'Neill L, Gannon J, Guinan E, Reynolds JV, Hussey J. , Multidisciplinary rehabilitation across the esophageal cancer journey, Journal of Thoracic Diseases, 9, (12), 2017, pE1140 - E1142Journal Article, 2017, DOI , TARA - Full Text
  • Sheill G; Brady L; Guinan E; Hayes B; Casey O; Greene J; Vlajnic T; Cahill F; Van Hemelrijck M; Peat N; Rudman S; Hussey J; Cunningham M; Grogan L; Lynch T; Manecksha R; McCaffrey J; Mucci L; Sheils O; O Leary J; M O Donnell D; McDermott R; Finn S. , The ExPeCT (Exercise, Prostate Cancer and Circulating Tumour Cells) Trial: Study protocol for a randomised controlled trial. , Trials, 18, 2017, p456-Journal Article, 2017, DOI
  • Sheill G, Guinan E, O Neill L., Hevey D., Hussey J. , Physical Activity and Advanced Cancer: The views of Oncology and Palliative Care Physicians in Ireland. , Irish Journal of Medical Science, 187, (2), 2018, p337 - 343Journal Article, 2018, DOI
  • Elliott J.A., Doyle, S.L., Murphy C.F., King S., Guinan E.M., Beddy, P., Narayanasamy, R. (, Sarcopenia: Prevalence, and Impact on Operative and Oncologic Outcomes in the Multimodal Management of Locally Advanced Esophageal Cancer , Annals of Surgery, 266, (5), 2017, p822 - 830Journal Article, 2017, DOI
  • Sheill. G., Guinan, E.M., O'Neill L, Hevey, D., Hussey, J. , Physical Activity and Advanced Cancer: The views of Chartered Physiotherapists in Ireland. , Physiotherapy Theory and Practice, 3, 2018, p1 - 8Journal Article, 2018, DOI
  • Gannon, J.A., Guinan E.M., Doyle S.L., Beddy P., Reynolds J.V., Hussey J. , Reduced Fitness and Physical Functioning are long-term Sequelae after Curative Treatment for Oesophageal Cancer: a Case-Control Study. , Diseases of the Esophagus, 30, (8), 2017, p1 - 7Journal Article, 2017, DOI
  • Moran, J., Guinan, E., McCormick, P., Larkin, J., Mockler, D., Hussey, J., Moriarty, J., Wilson, F. , Response to: Is prehabilitation limited to preoperative exercise? , Surgery, 162, (1), 2017, p192 - 193Journal Article, 2017, DOI
  • Bennett, A.E., O'Neill, L., Connolly, D., Guinan, E.M., Boland, L., Doyle, S.L., O'Sullivan, J., Reynolds, J.V., & Hussey, J., Patient experiences of a physiotherapy-led multidisciplinary rehabilitative intervention after successful treatment for oesophago-gastric cancer, Supportive Care in Cancer, 26, (8), 2018, p2615 - 2623Journal Article, 2018, DOI , URL
  • O'Neill, L.M., Guinan, E., Doyle, S.L., Bennett, A.E., Murphy, C., Elliott, J.A., O'Sullivan, J., Reynolds, J.V., Hussey, J., The RESTORE Randomized Controlled Trial: Impact of a multidisciplinary rehabilitative program on cardiorespiratory fitness in esophagogastric cancer survivorship, Annals of Surgery, 268, (5), 2018, p747 - 755Journal Article, 2018, DOI , URL
  • O'Neill, L. and Moran, J. and Guinan, E.M. and Reynolds, J.V. and Hussey, J., Physical decline and its implications in the management of oesophageal and gastric cancer: a systematic review, Journal of Cancer Survivorship, 12, (4), 2018, p601 - 618Journal Article, 2018, DOI , URL
  • Mulcahy S, Prendergast J, Foley G, O'Hare A, Murphy E, Guinan EM, Hussey J, Exercise Rehabilitation services provided by physiotherapy departments in Ireland., Irish Medical Journal , 111, (9), 2018, p818-Journal Article, 2018
  • Hussey JM, Yang T, Dowds J, O'Connor L, Reynolds JV, Guinan EM., Quantifying postoperative mobilisation following oesophagectomy., Physiotherapy, 105, (1), 2018, p126 - 133Journal Article, 2018, DOI
  • Guinan EM, Forde C, O'Neill L, Gannon J, Doyle SL, Valkenet K, Trappenburg JCA, van Hillegersberg R, Ravi N, Hussey JM, Reynolds JV., Effect of preoperative inspiratory muscle training on physical functioning following esophagectomy., Diseases of the Esphagus, 32, (32), 2018, pdoy091-Journal Article, 2018, DOI
  • Newton RU, Kenfield SA, Hart NH, Chan JM, Courneya KS, Catto J, Finn SP, Greenwood R, Hughes DC, Mucci L, Plymate SR, Praet SFE, Guinan EM, Van Blarigan EL, Casey O, Buzza M, Gledhill S, Zhang L, Galvão DA, Ryan CJ, Saad F., Intense Exercise for Survival among Men with Metastatic Castrate-Resistant Prostate Cancer (INTERVAL-GAP4): a multicentre, randomised, controlled phase III study protocol., BMJ Open, 8, (5), 2018Journal Article, 2018, DOI
  • Devenney KE, Sanders ML, Lawlor B, Olde Rikkert MGM, Schneider S; NeuroExercise Study Group, The effects of an extensive exercise programme on the progression of Mild Cognitive Impairment (MCI): study protocol for a randomised controlled trial., BMC Geriatrics, 17, (1), 2017, p75-Journal Article, 2017, DOI , URL
  • Devenney KE, Guinan EM, Kelly ÁM, Mota BC, Walsh C, Rikkert MO, Scneider S, Lalor B., Acute high-intensity aerobic exercise affects brain-derived neurotrophic factor in mild cognitive impairment: a randomised controlled study, BMJ Open Sport & Exercise Medicine, 5, 2019Journal Article, 2019, DOI
  • Linda O'Neill, Emer Guinan, Suzanne L Doyle, Jessie A. Elliott, Jacintha O'Sullivan, John V. Reynolds, Juliette Hussey, Rehabilitation Strategies following esophageal cancer (the ReStOre trial): a feasibility study, Diseases of the Esophagus, 30, (5), 2017, p1 - 8Journal Article, 2017, DOI
  • Guinan, E.M., Bennett, A.E., Doyle, S.L., O'Neill, L, Gannon, J., Foley, G., Elliott, J.A., O'Sullivan, J., Reynolds, J.V., & Hussey, J., Measuring the impact of oesophagectomy on physical functioning and physical activity participation: a prospective study, BMC Cancer, 19, (682), 2019Journal Article, 2019, DOI , URL , TARA - Full Text
  • Haberlin C, Broderick J., Guinan E.M, Darker C., Hussey J., O'Donnell D.M., E-Health based intervention to increase physical activity levels in people with cancer: protocol of a feasibility trial in an Irish acute hospital setting, BMJ Open, 9: e024999, 2019Journal Article, 2019, URL
  • Sheill G., Guinan E.M., Peat N., Hussey J , Considerations for Exercise Prescription in Patients with Bone Metastases: A Comprehensive Narrative Review. , Physical Medicine and Rehabilitation , 10, (8), 2018, p843 - 864Review Article, 2018, DOI
  • Stuckenschneider T, Askew C.D., Rudiger S., Cristina Polidori M., Abeln V, Vogt T, Krome A, Olde Rikkert M, Lawlor B., Schneider S., NeuroExercise Study Group , Cardiorespirataory fitness and cognitive function are positively related among participants with mild and subjective cognitive impairment, Journal of Alzheimer's Disease,, 62, (4), 2018, p1865 - 1875Journal Article, 2018, URL
  • Rudiger S., Stuckenschneider T, Vogt T, Abeln V., Lawlor B., Olde Rikkert M., Schneider S., NeuroExercise Study Group, Cognitive impairment is reflected by an increased difference between and imagined timed up and go performance, Dementia and Geriatric Cognitive Disorders, 44, (1-2), 2017, p55 - 62Journal Article, 2017, DOI
  • Guinan, E.M., Connolly, E.M., Hussey J , Exercise training in breast cancer survivors: a review of trials examining anthropometric and obesity-related biomarkers of breast cancer risk, Physical Therapy Reviews , 18, (2), 2013, p79 - 89Review Article, 2013, DOI
  • Elliott J.A., O'Byrne L., Foley G., Murphy C.F., Doyle S.L., Kind S., Guinan E.M., Narayanasamy R., Reynolds J.B, The effect of neoadjuvant chemoradiation on preoperative pulmonary physiology, postoperative respiratory complications and quality of life in patients with oesophageal cancer , British Journal of Surgery, 106, (10), 2019, p1341 - 1351Journal Article, 2019, URL
  • Sanders M.L., Stuckenschneider T, Devenney K.E. Lawlor B., Schneider S, Olde Rikkert M.G.M., NeuroExercise Study Group , ) Real world recruiting of older subjects with mild cognitive impairment for exercise trials: community readiness is pivotal, Journal of Alzheimer's Disease, 62, (2), 2018, p579 - 581Journal Article, 2018, URL
  • O'Neill, L.M., Bennett, A.E., Guinan, E., Reynolds, J.V., Hussey, J., Physical recovery in the first six months following oesophago-gastric cancer surgery. Identifying rehabilitative needs: a qualitative interview study, Disability and Rehabilitation, 2019, p1-8Journal Article, 2019, DOI , URL
  • O'Neill L., Knapp P., Doyle SL., Guinan E., Parker A.,Segurado R., Connolly D., O'Sullivan J., Reynolds JV., Hussey J, 'Patient and family co-developed participant information to improve recruitment rates, retention, and patient understanding in the Rehabilitation Strategies Following Oesophago-gastric and Hepatopancreaticobiliary Cancer (ReStOre II) trial: Protocol for a study within a trial (SWAT) [version 1; peer review: awaiting peer review]', 2019, -Protocol or guideline, 2019, DOI
  • Sheill G, Guinan E, Brady L, Hevey D, Hussey J., Exercise interventions for patients with advanced cancer: A systematic review of recruitment, attrition, and exercise adherence rates., Palliative and Supportive Care, 17, (6), 2019, p686 - 696Journal Article, 2019, DOI , URL
  • Elliott J.A., Docherty N., Murphy C., Eckhardt H., Doyle S.L., Guinan E., Ravi N., Reynolds J.V., Le Roux C, Changes in gut hormones, glycaemic response and symptoms after oesophagectomy, British Journal of Surgery, 106, (6), 2019, p735 - 746Journal Article, 2019, DOI
  • O'Neill L., Reynolds S., Sheill G., Guinan E., Mockler D., Geoghegan J., Conlon K., Reynolds, J.V., Hussey J., Physical function in patients with resectable cancer of the pancreas and liver-a systematic review, Journal of Cancer Survivorship, 2020Journal Article, 2020, DOI
  • Sheill G., Guinan E., O'Neill L., Normand C., Doyle SL., Moore S., Newell J., McDermott G., Ryan R., Reynolds JV., Hussey J., Preoperative exercise to improve fitness in patients undergoing complex surgery for cancer of the lung or oesophagus (PREHIIT): protocol for a randomized controlled trial, BMC Cancer, 2020Journal Article, 2020, DOI
  • O'NEILL L., GUINAN E., DOYLE S., CONNOLLY D., O'SULLIVAN J., BENNETT A., SHEILL G., SEGURADO R., KNAPP P., FAIRMAN C., NORMAND C., GEOGHEGAN J., CONLON K., REYNOLDS JV., HUSSEY J., Rehabilitation strategies following oesophagogastric and hepatopancreaticobiliary cancer (ReStOre II): a protocol for a randomised controlled trial, BMC Cancer, 20, 2020, p1 - 20Journal Article, 2020, DOI
  • O'Neill L., Guinan E., Doyle S., O'Connor L., Sheill G., Smyth E., Fairman C., Segurado R., Connolly D., O'Sullivan J., Reynolds JV., Hussey J, ReStOre@Home: Feasibility study of a virtually delivered 12-week multidisciplinary rehabilitation programme for survivors of upper gastrointestinal (UGI) cancer - study protocol, HRB Open Research, 2020Journal Article, 2020, DOI
  • Sheill G., Reynolds S., O'Neill L., Mockler D., Reynolds J.V., Hussey J., Guinan E, Cardiopulmonary Exercise Testing in Oesophagogastric Surgery: a Systematic Review, Journal of Gastrointestinal Surgery. , 24, 2020, p2667 - 2678Journal Article, 2020
  • Bennett, A.E., O'Neill, L., Connolly, D., Guinan, E., Boland, L., Doyle, S., O'Sullivan, J., Reynolds, J.V., Hussey, J., Perspectives of Esophageal Cancer Survivors on Diagnosis, Treatment, and Recovery., Cancers, 13, (1), 2021, p1-12Journal Article, 2021, DOI , URL
  • Kennedy, S.A., Annett, S.L., Dunne, M.R., Boland, F., O'Neill, L.M., Guinan, E.M., Doyle, S.L., Foley, E.K., Elliott, J.A., Murphy, C.F., Bennett, A.E., Carey, M., Hillary, D., Robson, T., Reynolds, J.V., Hussey, J., O'Sullivan, J.N., Effect of the Rehabilitation Program, ReStOre, on Serum Biomarkers in a Randomized Control Trial of Esophagogastric Cancer Survivors, Frontiers in Oncology, 11, (669078), 2021, p1-11Journal Article, 2021, DOI
  • ALKHAFFAF B., BLAZEBY JM, ET AL AND ON BEHALF OF THE GASTROS INTERNATIONAL WORKING GROUP, Methods for conducting international Delphi surveys to optimise global participation in core outcome set development: a case study in gastric cancer informed by a comprehensive literature review, Trials, 2021, phttps://doi.org/10.1186/s13063Journal Article, 2021
  • Sheill G., Hennessy M., O'Neill L., Reynolds S., Towns J., Gill M., Guinan E., Exercise and chronic health conditions in the community: A qualitative Study of Patients and Fitness instructors, Health and Social Care in the Community, 2021Journal Article, 2021, DOI
  • Grimes T, Guinan E, Interprofessional Education focused on Medication Safety: A Systematic Review., Journal of Interprofessional Care, 2022, p1 - 20Journal Article, 2022, DOI , URL , TARA - Full Text
  • Brennan, L. Sheill, G. O'Neill, L, O'Connor, L, Smyth, E. Guinan, E, Physical Therapists in Oncology Settings: Experiences in Delivering Cancer Rehabilitation Services, Barriers to Care, and Service Development Needs, Physical Therapy, 2022Journal Article, 2022, DOI
  • Brennan, L., Sadeghi, F., O'Neill, L., Guinan, E., Smyth, L. Sheill, G., Smyth, E., Doyle, S.L., Timon, C., Connolly, D., O'Sullivan, J., Reynolds, J.V., and Hussey, J., Telehealth Delivery of a Multi-Disciplinary Rehabilitation Programme for Upper Gastro-Intestinal Cancer: ReStOre@Home Feasibility Study, Cancers, 2022Journal Article, 2022, DOI
  • REYNOLDS SA., O'CONNOR L., McGEE A., QUINN KILCOYNE A., CONNOLLY A., MOCKLER D., GUINAN E., O'NEILL L, Recruitment rates and strategies in exercise trials in cancer survivorship: a systematic review, Journal of Cancer Survivorship, 2023Journal Article, 2023, DOI
  • O'Brien, A., Brennan, L., O'Neill, L, Guinan, E., Connolly, D., Reynolds, JV., and Hussey, J., Patient Experiences of a Telehealth Multidisciplinary Cancer Rehabilitation Programme: Qualitative Findings from the ReStOre@Home Feasibility Study, 2023Journal Article, 2023, DOI
  • O'Neill, L., Brennan, L., Sheill, G., Connolly D., Guinan, E., and Hussey, J., Moving Forward With Telehealth in Cancer Rehabilitation: Patient Perspectives From a Mixed Methods Study, JMIR Cancer, 2023Journal Article, 2023, DOI , URL
  • Elliott J., Guinan E., Reynolds J.V, Measurement and optimization of perioperative risk among patients undergoing surgery for esophageal cancer, Diseases of the Esophagus, 2023Journal Article, 2023
  • Sheill G., Brady L., Hayes B., Baird AM., Guinan E., Stanfill B., Vlayinic T., Casey O., Muphy V., Green J., Allott E., Hussey J., Cahill F., van Hemelrijck M., Peat N., Mucci L., Cunningham M., GroganL., Lynch T., Manecksha R.P., McCaffrey J., O"Donnell D., Sheils O., O"Leary J., Rudman S., McDermott R., Finn S., ExPeCT: A Randomised Trial Examining the Impact of Exercise on Quality of Life in Men with Metastatic Prostate Cancer, Supportive Care in Cancer, 31, (5), 2023, p292-Journal Article, 2023
  • Pertl M., Walsh A., Beghean R., Kinsella E., Collier S., Guinan E., Verling K., Monahan G., Wallace E., Doyle F., Effective maNagement of depression among patients witH cANCEr (ENHANCE): A protocol for a qualitative study on stakeholder perspectives of Network Meta-Analysis findings on the most effective treatments for depression, HRB Open Research, 2022Journal Article, 2022
  • Sheill G., Hennessy M., Devenney K., Reynolds S., Towns J., Gill M., Guinan E., A hospital to community exercise referral pathway: results of a pilot project., Irish Journal of Medical Science., 2022Journal Article, 2022
  • O"Brien K, Townsand L, Dowds J, Bannan C, Nadarajan P, Kent B, Murphy N, Sheill G, Martin-Loeches I, Guinan E, 1-year quality of life and health-outcomes in patients hospitalised with COVID-19: a longitudinal cohort study., Respiratory Research, 23, (1), 2022, p115-Journal Article, 2022
  • Guinan E.M., Devenney K., Quinn C., Sheill G., MacEochagáin., Kennedy M.J., McDermott R., Balding L, Associations between physical activity, skeletal related events and patient reported outcomes in patients with bone metastases., Seminars in Oncology Nursing, 15, (15), 2022, p1274-Journal Article, 2022
  • O"Leary N and Guinan E.M., A national survey to map Interprofessional Education in Ireland., Journal of Interprofessional Care, 22, 2022, p1-Journal Article, 2022
  • Finn M., Sherlock M., Feehan S., Guinan E.M., Moore K.B, Adherence to physical activity recommendations and barriers to physical activity participation among adults with type 1 diabete, Irish Journal of Medical Science, 2021Journal Article, 2021
  • Stuckenschneider T., Sanders M.L., Devenney K.E., Aaronson J.A., Abeln V., Claassen J.A.H.R., Guinan E., Lawlor B., Meeusen R., Montag C., Olde Rikkert M.G.M., Polidori M.C., Reuter M., Schulz R-J., Vogt T., Weber B., Kessels R.P.C., Schneider S., NeuroExercise: The Effect of a 12-Month Exercise Intervention on Cognition in Mild Cognitive Impairment A Multicenter Randomized Controlled Trial., Frontiers in aging neuroscience, 2021Journal Article, 2021
  • Hayes B., Brady L, Sheill G., Baird AM., Guinan E., Stanfill B., Dunne J., Holden D., Vlajnic T., Casey O., Murphy V., Greene J., Allott E.H., Hussey J.,Cahill F., Van Hemelrijck M., Peat N., Mucci L.A., Cunningham M., Grogan L., Lynch T., Manecksha R.P., McCaffrey J., O"Donnell D.M., Sheils O., O"Leary J.J., Rudman S., McDermott R., Finn S, ) Circulating Tumour Cell Numbers Correlate with Platelet Count and Circulating Lymphocyte Subsets in Med with Advanced Prostate Cancer: Data from the ExPeCT Clinical Trial (CTRIAL-IE 15-21), Cancers, 13, 2021, p4690-Journal Article, 2021
  • Smyth E., O"Connor L., Mockler D., Reynolds J.V., Hussey J., Guinan E., Preoperative high intensity interval training for oncological resections: A systematic review and meta-analysis., Surgical Oncology, 2021Journal Article, 2021
  • Brady L, Hayes B, Sheill G, Baird AM, Guinan E., Stanfill B., Vlajnic T., Casey O., Murohy V., Green J., Allott E.H., Hussey J., Cahill F., Van Hemelrijck M., Peat N., Mucci L., Cunningham M., Grogan L., Lynch T., Manecksha R.P., McCaffrey J., O"Donnell D., Sheils O., O"Leary J., Rudman S., McDermott R., Finn S., Platelet Cloaking of Circulating Tumour Cells in Patients with Metastatic Prostate Cancer: Results from ExPeCT, a Randomised Controlled Trial, PLOS ONE., 2020Journal Article, 2020
  • Walsh JM, Hussey J, Guinan E, O' Donnell D, 'Pragmatic randomized controlled trial of individually prescribed exercise versus usual care in a heterogeneous cancer survivor population': a feasibility study PEACH trial: prescribed exercise after chemotherapy., BMC Cancer, 10, (42), 2010Journal Article, 2010, DOI , URL , TARA - Full Text
  • Guinan E, Hussey J, Broderick JM, Lithander FE, O'Donnell D, Kennedy MJ, Connolly EM, The effect of aerobic exercise on metabolic and inflammatory markers in breast cancer survivors-a pilot study., Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 21, (7), 2013, p1983-1992Journal Article, 2013, DOI , URL , TARA - Full Text
  • Guinan EM, Connolly EM, Kennedy MJ, Hussey J., The presentation of metabolic dysfunction and the relationship with energy output in breast cancer survivors: a cross-sectional study, Nutr J. , 12, (1), 2013Journal Article, 2013, DOI
  • Broderick JM, Guinan E, Kennedy MJ, Hollywood D, Courneya KS, Culos-Reed SN, Bennett K, O'Donnell DM, Hussey J, Feasibility and efficacy of a supervised exercise intervention in de-conditioned cancer survivors during the early survivorship phase, Journal of Cancer Survivorship, 7, (4), 2013, p551 - 562Journal Article, 2013, DOI
  • Broderick, J. M. Guinan, E. Donnell, D. M. O' Hussey, J. Tyrell, E. Normand, C., Calculating the costs of an 8-week, physiotherapy-led exercise intervention in deconditioned cancer survivors in the early survivorship period (the PEACH trial), Physiotherapy, 100, (2), 2014, p182 - 184Journal Article, 2014, TARA - Full Text
  • Valkenet K, Trappenburg JC, Gosselink R, Sosef MN, Willms J, Rosman C, Pieters H, Scheepers JJ, de Heus SC, Reynolds JV, Guinan E, Ruurda JP, Rodrigo EH, Nafteux P, Fontaine M, Kouwenhoven EA, Kerkemeyer M, van der Peet DL, Hania SW, van Hillegersberg R, Backx FJ, Preoperative inspiratory muscle training to prevent postoperative pulmonary complications in patients undergoing esophageal resection (PREPARE study): study protocol for a randomized controlled trial., Trials, 15, (1), 2014, p144Journal Article, 2014, DOI , TARA - Full Text
  • Guinan EM, Connolly EM, Healy LA, Carroll PA, Kennedy MJ, Hussey J , The Development of the Metabolic Syndrome and Insulin Resistance After Adjuvant Treatment for Breast Cancer, Cancer Nursing, Epub ahead of print, 2013Journal Article, 2013, DOI
  • Guinan, E.M., Connolly, E.M., Hussey J , Physical Activity and Obesity Related Biomarkers in Breast Cancer Survivors, Physical Therapy Reviews, 18, (3), 2013, p229 - 231Review Article, 2013, DOI
  • Guinan E., Hussey J., McGarrigle S.A., Healy L.A., O'Sullivan J.N., Bennett K., Connolly E.M., A Prospective Investigation of Predictive and Modifiable Risk Factors for Breast Cancer in Unaffected BRCA1 and BRCA2 Gene Carriers., BMC Cancer, 13, (138), 2013Journal Article, 2013, DOI
  • Promoting Leadership Skills Through Interprofessional Education in, editor(s)Morison S , Leadership: Perception, Influences and Gender Differences, NOVA science publishers, 2017, pp103 - 139, [Guinan E.M. and McGowen E.]Book Chapter
  • O'Neill, L., Murphy, F., Reidy, D., Poisson, C., Hussey, J., and Guinan, E., Development and Initial Implementation of a Clinical Monitoring Strategy in a Non-regulated Trial: a research note from the ReStOre II Trial [version 1; peer review: awaiting peer review], HRB Open Research, 2023Journal Article, URL
  • O'Neill L, Murphy F, Reidy D, Poisson C., Hussey J., Guinan E, Development and Initial Implementation of a Clinical Monitoring Strategy in a Non-regulated Trial: a research note from the ReStOre II Trial, HRB Open Research, 6, (46), 2023Journal Article
  • 19. Sadeghi F., Mockler D., Guinan E.M., Hussey J, Doyle S.L., The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review, Nutrients, 13, 2021, p2842-Journal Article

Research Expertise

  • Title
    Managing depression among patients with cancer: Identifying what works best through Network Meta-Analysis and Stakeholder consultation
    Summary
    Irish Cancer Society funded project examining management strategies for depression in cancer through network meta-analysis and stakeholder engagement
    Funding Agency
    Irish Cancer Society
    Date From
    2019
  • Title
    Developing and Feasibility Testing of a Pragmatic, Patient-Centred Exercise Intervention During Chemotherapy: A Mixed-Methods Approach
    Summary
    This Provost"s PhD Project Award with levered funding from the Irish Cancer Society is examining the issue of physical activity and exercise training during chemotherapy.
    Funding Agency
    Trinity College Dublin
    Date From
    March 2022
  • Title
    Personalised exercise rehabialitino in Cancer Survivorship (PERCS)
    Summary
    PERCS is an Irish Cancer Society funded project aiming to evaluate the real-world application of an exercise triage and referral system, supported by an online repository of exercise rehabilitation resources specific to Ireland, on physical and psychosocial outcomes in cancer survivors. Work Package 1 has delivered a co-design website www.cancerrehabilitation.ie
    Funding Agency
    Irish Cancer Society
    Date From
    Feb 2022
  • Title
    The Role of Cancer Support Community in Cancer Research
    Summary
    Irish Cancer Society Funded Networking Award to work with community cancer support centres in Ireland to support research activity.
    Funding Agency
    Irish Cancer Society
    Date From
    Aug 2023
  • Title
    Preoperative Exercise to Improve Fitness in Patients Undergoing Complex Surgery for Cancer of the Lung or Oesophagus
    Summary
    PreHIIT is an Irish Cancer Society/HRB funded trial examining exercise prehabilitation in complex cancer surgeries.
    Funding Agency
    MRCG-HRB
    Date From
    07.12.2018
    Date To
    06.02.2024
  • Title
    Rehabilitative Strategies Following Oesophageal Cancer (ReStOre trial)
    Summary
    This project comprises two studies; 1)a longitudinal assessment of the effect of curative treatment for oesopahgeal cancer on physical performance and 2) an investigation of the feasibility and efficacy of a rehabilitative programme of exercise and dietary intervention following oesophageal cancer treatment completion.
    Funding Agency
    Health Research Board (HRB)
    Date From
    Oct 2014
  • Title
    Knowledge Exchange and Dissemination: Community Exercise
    Summary
    This research programme aims to enable patients who are participating in exercise training programmes at the Wellcome Trust-HRB Clinical Research Facility at St James's Hospital to exercise locally by addressing patient-reported barriers to community exercise participation
    Funding Agency
    Health Research Board
    Date From
    01.01.2018
    Date To
    31.12.2018
  • Title
    Exercise prescription in patients with bone metastases: identifying clinical tools to overcome clinician concerns regarding skeletal related events.
    Summary
    Irish Cancer Society funded cross sectional examination of the relationship between physical activity, patient reported outcomes and skeletal related events in patients with bone metastases.
    Funding Agency
    Irish Cancer Society and the All Ireland Institute of Hospice and Palliative Care Research Award.
    Date From
    01.02.2019
    Date To
    01.02.2021
  • Title
    All-Ireland Cancer Network (All CaN) in Oesophageal cancer
    Summary
    The AllCaN Grant Programme was created as part of (the Irish research charity) Breakthrough Cancer Research"s new 5-year research strategy (Making More Survivors), to support and facilitate knowledge sharing between exemplary teams in institutions across the island of Ireland, who are taking on less survivable cancers. The first of these AllCaN Grants will focus on oesophageal cancer; funding innovative research to improve early detection and outcomes for patients with, or at risk of, developing the disease. Ireland and the UK have the highest incidence of oesophageal adenocarcinoma worldwide.
    Funding Agency
    Breakthrough Cancer Research
  • Title
    Rehabilitation Strategies following Oesophagogastric and Hepatopancreaticobiliary Cancer
    Summary
    ReStOre is a Health Research Board (HRB) funded trial examining the role of structured multi-disciplinary rehabilitation on recovery following oesophageal cancer. ReStOre II is ongoing as a Definitive Intervention examining multi-disciplinary rehabilitation in upper gastrointestinal cancer
    Funding Agency
    Health Research Board
    Date From
    01.05.2019
    Date To
    01.05.2024
  • Title
    An alternative pathway to improve access to cascade genetic testing (CasGenTest) for people with a high risk for hereditary cancer predisposition
    Summary
    Irish Cancer Society funded Allied Health Professional Award to Dr Rosie O'Shea which will examine an alternative pathway to improve access to cascade genetic testing using a digital platform.
    Funding Agency
    Irish Cancer Society
    Date From
    December 2023

Recognition

  • CORU Physiotherapy Registration Board Present
  • Irish Society of Chartered Physiotherapists (ISCP) present
  • 2022 - Member of the Irish Psycho-Social Oncology Network (IPSON) Steering Committee representing Cancer Rehabilitation 2022
  • Co-chair of the Irish Network of Healthcare Educators Special Interest Group in Interprofessional Education and Collaborative Practice 2020 - present
  • 2021 - present: Member of the Physical Activity and Exercise Subgroup at the National Cancer Control Programme 2021