Pedigree Genomics Workshop 2026

Pedigree Genomics Workshop

Friday 8th May 2026 (Hybrid)

 

Are you analysing genomic data in pedigrees?

If your answer is yes, then this workshop is for you!!


This workshop will introduce established and new approaches to analysing pedigree genomics data. By attending this workshop you will learn about haplotypes and how they affect your linkage analyses, how identity-by-descent and haplotype phasing can be used to identify risk-variants in pedigree studies and you will also learn about a new tool BICEP: Bayesian Inference for rare genomic variant Causality Evaluation in Pedigrees. You will also hear some real life stories from the genome from our invited speaker Dr Pippa Thomson. During the day there will be many opportunities to gain hands-on experience of the tools and approaches.

Date, time, and place

  • Friday 8th May 2026
  • 09:00 to 17:00 Irish Standard Time (IST)
  • Hybrid, take part in person or online (Zoom)
    In person will take place in the Trinity Translational Medicine Institute.

Fees

This online workshop is FREE. For those attending in person lunch, teas and coffees will be provided.

Provisional Schedule

Time  
09:00 - 09:30 Registration, Welcome
09:30 - 11:00 Haplotypes - what are they and how do they effect your linkage analyses (Dr Pippa Thomson)
11:00 - 11:30 Using identity-by-descent and haplotype phasing to identify risk-variants in pedigree studies (Dr Niamh Ryan)
11:30 - 11:45 BREAK
11:45 - 12:15 BICEP - Bayesian inference for rare genomic variant causality evaluation in pedigrees (Dr Eleisa Heron)
12:15 - 13:00 BICEP - installation, testing (Dr Cathal Ormond)
13:00 - 14:00 LUNCH
14:00 - 14:30 BICEP - worked examples (Dr Cathal Ormond)
14:30 - 15:30 BICEP Advanced - prior choice, different variant types and challenging pedigree structures (Dr Cathal Ormond)
15:30 - 16:00 BREAK
16:00 - 17:00 Invited Speaker Dr Pippa Thomson: "Stories from the genome or what one family has taught me about psychiatric genetics"

Workshop Prerequisites

It is expected that workshop attendees will have some previous experience in handling next generation sequencing data and annotation databases.

Basic statistical experience will be required however, experience with the Bayesian approach is not and details of this will be provided during the workshop.

Speakers

Dr Pippa Thomson, The University of Edinburgh

Dr Eleisa Heron, Trinity College Dublin

Dr Cathal Ormond, Trinity College Dublin

Dr Niamh Ryan, Trinity College Dublin

Further details and resources

Pedigree Genomics Workshop

BICEP Manuscript

BICEP GitHub

Organised by

Eleisa Heron
Cathal Ormond

Sign Up

Please click here to sign up.

 

If further details are required contact Dr Elizabeth Heron: eaheron@tcd.ie