Medicine

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Trinity Biomedical Sciences Institute
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Dr. Dania Movia

Dr. Dania Movia

Assistant Professor

Dr Dania Movia is an Assistant Professor of the Discipline of Radiation Therapy. She is also Principal Investigator of the Laboratory for Biological Characterisation of Advanced Materials (LBCAM) at the Trinity Translational Medicine Institute (TTMI), associated with the Trinity St James's Cancer Institute.

She received her PhD at Trinity College Dublin in 2012, and subsequently she was awarded a Special Purpose Certificate in Academic Practice by the same university in 2018.

Dr Movia champions the reduction and replacement of animal testing via research and training of young scientists. Her current research work focuses on developing new, non-animal methodologies (NAMs) that can replace animal studies in cancer and lung toxicity research. These technologies are based on human cells growing as complex, 3D in vitro tissues, outside the human body.

Dr Movia has received support and funding from several organisations including the Irish Research Council (IRC), Science Foundation Ireland (SFI), Animal-Free Research UK, the Johns Hopkins Center for Alternatives to Animal Testing Award (CAAT), and the European Commission. She has authored more than 40 peer-reviewed publications, edited 1 e-book and she has acted as Guest Editor in "Animals" (MDPI) and "Front. Bioeng. Biotechnol." (Frontiers) journals. She is currently editing a book for the book series Methods in Molecular Biology, published by Springer Nature.

Dr Movia is part of the Scientific Advisory Panel of Animal-Free Research UK and FRAME. She is also a member of a number of professional bodies and organisations, which include the Irish Lung Cancer Alliance (ILCA) and Cancer Trials Ireland.

Dr Movia lectures in the Trinity BSc in Radiation Therapy and in the MSc in Molecular Medicine.

An updated list of her publications can be found at: https://scholar.google.com/citations?user=T60uEacAAAAJ&hl=en&oi=ao

Dr Dania Movia Assistant Professor in Biomedical & Health Services at the Department of Biology at Maynooth University. Adjunct Assistant Professor at Radiation Therapy of Trinity College Dublin.

Dr Dania Movia is an Assistant Professor in Biomedical & Health Services at the Department of Biology at Maynooth University. She is also an Adjunct Assistant Professor at the Discipline of Radiation Therapy of Trinity College Dublin. She graduated in Chemistry and Pharmaceutical Technologies in 2007 from the University of Trieste (Italy). She then obtained her PhD at Trinity College Dublin in 2012, and she was awarded a Special Purpose Certificate in Academic Practice and a Master in Arts (jure officii) by the same university in 2018 and 2023, respectively.

Dr Movia champions the reduction/replacement of animal testing via research and training of young scientists. Her current research work focuses on developing new, non-animal methodologies (NAMs) that can replace animal studies in lung cancer and lung toxicity research. Recently, she established the first wet-lab on animal-free lung translational research in the Republic of Ireland, the Humane Biomedical Research Lab, housed at the Biomedical Sciences building in the Maynooth University North Campus. Her research group collaborates closely with the LBCAM, through the exchange of expertise and research interests.

Dr Movia has received funding in excess of €2M from several national, European and international agencies, and has authored more than 45 peer-reviewed publications. She is part of several professional bodies and organisations, which include the Irish Lung Cancer Alliance and Cancer Trials Ireland, and an active member of the scientific advisory panels of Animal-Free Research UK and FRAME-UK.

Publications and Further Research Outputs

  • Del Canto, E., Flavin, K., Movia, D., Navio, C., Bittencourt, C., Giordani, S., Critical investigation of defect site functionalization on single-walled carbon nanotubes, Chemistry of Materials, 23, (1), 2011, p67-74Journal Article, 2011, DOI
  • Moore C., Movia D., Smith R., Hanlon D., Lebre F., Lavelle E., Byrne H., Coleman J., Volkov Y., McIntyre J., Industrial grade 2D molybdenum disulphide (MoS2): an in vitro exploration of the impact on cellular uptake, cytotoxicity, and inflammation, 2D Materials, 4, (2), 2017Journal Article, 2017, DOI , URL
  • Hutchinson D, Muller J, McCarthy JE, Gun'ko YK, Verma NK, Bi X, Di Cristo L, Kickham L, Movia D, Prina-Mello A, Volkov Y, Cadmium nanoparticles citrullinate cytokeratins within lung epithelial cells: cadmium as a potential cause of citrullination in chronic obstructive pulmonary disease, International Journal of Chronic Obstructive Pulmonary Disease , 13, 2018, p441 - 449Journal Article, 2018, URL , TARA - Full Text
  • Dania Movia, Despina Bazou, Adriele Prina-Mello, ALI multilayered co-cultures mimic biochemical mechanisms of the cancer cell-fibroblast cross-talk involved in NSCLC MultiDrug Resistance, BMC Cancer, 19, (1), 2019Journal Article, 2019, DOI
  • Special Issue "Use of 3D Models in Drug Development and Precision Medicine: Advances and Outlook", Frontiers in Bioengineering and Biotechnology, 2020-2021Editorial Board, 2020
  • Special Issue "Replacing Animal Testing in Research"A Scientific and Regulatory Perspective of Current Efforts Towards the 1R", Animals (MDPI), 2021-2022Editorial Board, 2021
  • Mullen, S. and Movia, D., The role of extracellular vesicles in non-small-cell lung cancer, the unknowns, and how new approach methodologies can support new knowledge generation in the field, European Journal of Pharmaceutical Sciences, 188, (106516), 2023Journal Article, 2023, DOI , URL
  • Movia D., Del Canto E. and Giordani S., Spectroscopy of Single-Walled Carbon Nanotubes in Aqueous Surfactant Dispersion, physica status solidi (b), 246, (11-12), 2009, p2704 - 2707Journal Article, 2009, DOI , TARA - Full Text
  • Movia D., Del Canto E., Giordani S., Purified and Oxidized Single Walled Carbon Nanotubes as Robust Near IR Fluorescent Probes for Molecular Imaging, Journal of Physical Chemistry C, 114, (43), 2010, p18407-18413Journal Article, 2010, DOI
  • Thakur G., Micic M., Yang Y., Li W., Movia D., Giordani S., Zhang H. and Leblanc R., Conjugated Quantum Dots Inhibit the Amyloid β (1-42) Fibrillation Process, International Journal of Alzheimer's Disease, 2011, 2011, p502386Journal Article, 2011, DOI , TARA - Full Text
  • Del Canto E., Flavin K., Movia D., Navio C., Bittencourt C., Giordani S., A Critical Investigation of Defect Site Functionalization on Single Walled Carbon Nanotubes, Chemistry of Materials, 23, (1), 2011, p67-74Journal Article, 2011, DOI
  • Toxicity of carbon nanotubes in, Handbook of Green Chemistry - Green Processes (- Green Nanoscience), Germany, Wiley - VCH, 2013, pp175 - 216 , [Movia D. and Giordani S.]Book Chapter, 2013
  • Del Canto E., Flavin K., Movia D., Giordani S., Oxidized Single-Walled Carbon Nanotubes: removal of carbonaceous functionalized material by washing with solvents or base, MRS Proceedings, 1362, 2011, pmrss11-1362-qq09-44Journal Article, 2011, DOI
  • Del Canto E., Natali M., Movia D. and Giordani S., Photo-controlled Uptake and Release of Zinc Metal Ions by Spiropyran receptors anchored to Single-Walled Carbon Nanotubes, Phys. Chem. Chem. Phys. , 14, (17), 2012, p6034 - 6043Journal Article, 2012, DOI , TARA - Full Text
  • Multilayered nanoparticles for personalized medicine: translation into clinical markets in, editor(s)Raj Bawa, Gerald F. Audette, Israel Rubinstein , Handbook of Clinical Nanomedicine: Nanoparticles, Imaging, Therapy and Clinical Applications, Pan Stanford Publishing, 2016, pp299 - 318, [Dania Movia, Craig Poland, Lang Tran, Yuri Volkov, Adriele Prina-Mello]Book Chapter, 2016, DOI
  • Movia, D., Gerard, V., Maguire, C.M., Jain, N., Bell, A.P., Nicolosi, V., O'Neill, T., Scholz, D., Gun'ko, Y., Volkov, Y., Prina-Mello, A., A safe-by-design approach to the development of gold nanoboxes as carriers for internalization into cancer cells, Biomaterials, 35, (9), 2014, p2543-2557Journal Article, 2014, DOI
  • Gavigan-Imedio J.D., Movia D., Volkov Y., Prina-Mello A., Nanomedicine translational oncology: a perspective to cancer treatment, EuroNanoForum, Dublin, Ireland, June 2013, 2013Oral Presentation
  • Movia D., Del Canto E., Giordani S., Purified and Oxidized SWNTs: potential NIR fluorescence probes for molecular imaging, ChemOnTubes 2010, Arcachon, France, 11-15/04/2010, 2010Oral Presentation

Research Expertise

  • Title
    Towards a kinder yet impactful way to conduct lung cancer research
    Summary
    Funding Agency
    School of Medicine, Trinity College Dublin
    Date From
    2022
    Date To
    2023
  • Title
    Developing in vitro non-animal methods (NAMs) for mimicking human lung tumour complexity
    Summary
    Funding Agency
    Enterprise Ireland
    Date From
    2020
    Date To
    2021
  • Title
    Photochromic Network Polymers and Supramolecular Modification of Single-Walled Carbon Nanotubes
    Summary
    Funding Agency
    Irish Research Council
    Date From
    2008
    Date To
    2012
  • Title
    Capturing human tumour complexity in 3D lung cancer models for predicting drugs' efficacy in patient
    Summary
    Funding Agency
    Enterprise Ireland
    Date From
    2018
    Date To
    2018
  • Title
    Extracellular vesicles in Non-Small-Cell Lung Cancer - Finding allies among the enemies
    Summary
    Funding Agency
    Science Foundation Ireland
    Date From
    2022
    Date To
    2026
  • Title
    INEDITED - Improve NanomEDIcine Translation into clinical lung cancEr Drugs
    Summary
    Funding Agency
    Irish Research Council
    Date From
    2015
    Date To
    2017
  • Title
    Risk Management of Biomaterials (BIORIMA)
    Summary
    Funding Agency
    European Union
    Date From
    2017
    Date To
    2022
  • Title
    Developing novel inhaled bioengineered Extracellular Vesicle RNA based advanced therapeutics, delivered by tailored aerosol delivery technology for the treatment of lung cancer (INSPIRE)
    Summary
    Funding Agency
    European Commission
    Date From
    2022
    Date To
    2025
  • Title
    Pre-clinical models for predicting the toxicity, absorption and biodistribution of inhaled nanomaterials in humans
    Summary
    Funding Agency
    Johns Hopkins University Center for Alternatives to Animal Testing (CAAT)
    Date From
    2018
    Date To
    2020

Pharmacology and pharmaceutical sciences, Nanotechnology, Cancer,

Recognition

  • Best Material Science Poster, 33rd Annual Microscopy Society of Ireland (MSI) meeting 2009
  • Paper of the Year 2012, Society of Toxicology Board 2012
  • Research Award in recognition for the publication of an internationally peer-reviewed publication of the highest quality. 2012
  • Irish Lung Cancer Alliance (ILCA) member Present
  • Cancer Trials Ireland membership Present
  • EACR (European Association for Cancer Research) membership Present
  • Review Editor, Predictive Toxicology, specialty section of the Frontiers in Pharmacology journal. 2021
  • Guest Editor, Animals (MDPI) journal - Topic title: Replacing Animal Testing in Research"A Scientific and Regulatory Perspective of Current Efforts Towards the 1R. 2021
  • Scientific Advisory Panel member, Animal-Free Research UK. 2019
  • Topic Editor for the Frontiers in Bioengineering and Biotechnology journal (Topic: Use of 3D Models in Drug Development and Precision Medicine: Advances and Outlook). 2019
  • Scientific Advisory Panel member, FRAME UK 2021
  • Reviewer for several international scientific journals. A list is available at: http://www.webofscience.com/wos/author/record/T-6552-2018 Present