Dr. Martin Barr

• Barr MP, Gray SG, Gately K, Hams E, Fallon PG, Davies AM, Richard DJ, Pidgeon GP, O'Byrne., VEGF is an autocrine growth factor, signalling through Neuropilin-1 in non-small cell lung cancer, Molecular Cancer, In Press, (In Press), 2015Journal Article, 2015
• Barr MP, O'Byrne KJ, Al-Sarraf N, Gray SG., VEGF-mediated cell survival in NSCLC: Implications for epigenetic targeting of VEGF receptors as a therapeutic approach, Epigenomics, 2015Journal Article, 2015
• MacDonagh L, Gray SG, Cuffe S, Finn SP, O'Byrne KJ, Barr MP, The emerging role of microRNAs in resistance to lung cancer treatments, Cancer Treatment Reviews, 41, (2), 2015, p160 - 169Review Article, 2015, URL
• Dowling P, Pollard D, Larkin AM, Michael H, Meleady P, Gately K, O'Byrne K, Barr MP, Lynch V, Ballot J, Crown J, Moriarity M, O'Brien E, Morgan R, Clynes M. , Abnormal levels of heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) in tumour tissue and blood samples from patients diagnosed with lung cancer , Molecular Biosystems, 2014Journal Article, 2014, URL
• O'Grady S, Finn SP, Cuffe S, Richard DJ, O'Byrne KJ, Barr MP., The role of DNA repair pathways in cisplatin resistant lung cancer, Cancer Treatment Reviews, 40, (10), 2014, p1161 - 1170Review Article, 2014, URL
• Heavey S, Godwin P, Baird AM, Barr MP, Umezawa K, Cuffe S, Finn S, O'Byrne K, Gately K., Strategic targeting of the PI3K-NFkB axis in cisplatin resistant NSCLC, Cancer Biology & Therapy, 15, (10), 2014, p1367 - 1377Journal Article, 2014, URL
• Barr MP, MacDonagh L, O'Byrne KJ., Markers of response to platinum-based chemotherapy in lung cancer, Lung Cancer Management, 2, (3), 2013, p1 - 13Review Article, 2013
• Gao Y, Baird AM, Barr MP, Gately K, O'Byrne KJ, Gray SG., Epigenetic therapy for cisplatin resistance in non-small cell lung cancer: the way forward?, Lung Cancer Management, 2, (1), 2013, p1 - 4Review Article, 2013
• O'Flathery JD, Barr M, Fennell D, Richard D, Reynolds J, O'Leary J, O'Byrne K., The Cancer Stem-Cell Hypothesis: Its Emerging Role in Lung Cancer Biology and its Relevance for Future Therapy, Journal of Thoracic Oncology, 7, (12), 2012, p1880 - 1890Review Article, 2012, URL
• Molecular Mechanisms of Cisplatin Resistance in Lung Cancer. in, editor(s)Gately, KA , Lung Cancer: A Comprehensive Overview. , New York, Nova Science Publishers, 2013, pp171 - 190, [Martin P Barr]Book Chapter, 2013
• MacDonagh,Lauren , Gray,Steven George, Finn,Stephen P. , Cuffe,Sinead D. , O'Byrne,Kenneth John, Barr,Martin P. , The emerging role of microRNAs in resistance to lung cancer treatments, Cancer Treatment Reviews, 41, (2), 2015, p160-169Journal Article, 2015, DOI
• Dowling P, Pollard D, Larkin A, Henry M, Meleady P, Gately K, O'Byrne K, Barr MP, Lynch V, Ballot J, Crown J, Moriarty M, O'Brien E, Morgan R, Clynes M, Abnormal levels of heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) in tumour tissue and blood samples from patients diagnosed with lung cancer., Molecular bioSystems, 2014Journal Article, 2014, DOI
• Barr MP, Gray SG, Gately K, Hams E, Fallon PG, Davies AM, Richard DJ, Pidgeon GP, O'Byrne KJ., Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer, Molecular Cancer, ( ), 2015, p0.1186/s12943-015-0310-8Journal Article, 2015, DOI , TARA - Full Text
• Leon, G., MacDonagh, L., Finn, S.P., Cuffe, S., Barr, M.P., Cancer stem cells in drug resistant lung cancer: Targeting cell surface markers and signaling pathways, Pharmacology and Therapeutics, 158, 2016, p71 - 90Journal Article, 2016
• MacDonagh L, Gray SG, Breen E, Cuffe S, Finn SP, O'Byrne KJ, Barr MP, Lung cancer stem cells: The root of resistance., Cancer letters, 372, (2), 2016, p147-56Journal Article, 2016, DOI
• Cregan S, McDonagh L, Gao Y, Barr MP, O'Byrne KJ, Finn SP, Cuffe S, Gray SG, KAT5 (Tip60) is a potential therapeutic target in malignant pleural mesothelioma., International journal of oncology, 48, (3), 2016, p1290-6Journal Article, 2016, DOI
• Heavey S, Cuffe S, Finn S, Young V, Ryan R, Nicholson S, Leonard N, McVeigh N, Barr M, O'Byrne K, Gately K, In pursuit of synergy: An investigation of the PI3K/mTOR/MEK co-targeted inhibition strategy in NSCLC, Oncotarget, 7, (48), 2016, p79526 - 79543Journal Article, 2016, DOI , URL , TARA - Full Text
• MacDonagh Lauren, Gallagher Michael F, Ffrench Brendan, Gasch Claudia, Breen Eamon, Gray Steven G, Nicholson Siobhan, Leonard Niamh, Ryan Ronan, Young Vincent, O'Leary John J, Cuffe Sinead, Finn Stephen P, O'Byrne Kenneth J, Barr Martin P, Targeting the cancer stem cell marker, aldehyde dehydrogenase 1, to circumvent cisplatin resistance in NSCLC , Oncotarget , 8 , (42 ), 2017, p72544 - 72563Journal Article, 2017, DOI , URL
• Heavey S, Dowling P, Moore G, Barr MP, Kelly N, Maher SG, Cuffe S, Finn SP, O'Byrne KJ, Gately K., Development and characterisation of a panel of phosphatidylinositide 3-kinase - mammalian target of rapamycin inhibitor resistant lung cancer cell lines., Scientific Reports, 8, (1), 2018, p1652-Journal Article, 2018, DOI , TARA - Full Text
• Knopf KM, Murphy BL, MacMillan SN, Baskin JM, Barr MP, Boros E, Wilson JJ., In Vitro Anticancer Activity and in Vivo Biodistribution of Rhenium(I) Tricarbonyl Aqua Complexes., Journal of the American Chemistry Society, 139, (40), 2017, p14302 - 14314Journal Article, 2017
• Yan Y, Jiang K, Liu P, Zhang X, Dong X, Gao J, Liu Q, Barr MP, Zhang Q, Hou X, Meng S, Gong P., Bafilomycin A1 induces caspase-independent cell death in hepatocellular carcinoma cells via targeting of autophagy and MAPK pathways., Scientific Reports, 6, 2016, p37052-Journal Article, 2016
• Hu L, Sun S, Wang T, Li Y, Jiang K, Lin G, Ma Y, Barr MP, Song F, Zhang G, Meng S., Oncolytic newcastle disease virus triggers cell death of lung cancer spheroids and is enhanced by pharmacological inhibition of autophagy., American Journal of Cancer Research, 5, (12), 2015, p3612 - 3623Journal Article, 2015
• Barr MP, O'Byrne KJ, Al-Sarraf N, Gray SG., VEGF-mediated cell survival in non-small-cell lung cancer: implications for epigenetic targeting of VEGF receptors as a therapeutic approach., Epigenomics, 7, (6), 2015, p897 - 910Journal Article, 2015
• Barr MP, Gray SG, Gately K, Hams E, Fallon PG, Davies AM, Richard DJ, Pidgeon GP, O'Byrne KJ., Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer., Molecular Cancer, 14, 2015, p45-Journal Article, 2015
• Dowling P, Pollard D, Larkin A, Henry M, Meleady P, Gately K, O'Byrne K, Barr MP, Lynch V, Ballot J, Crown J, Moriarty M, O'Brien E, Morgan R, Clynes M., Abnormal levels of heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) in tumour tissue and blood samples from patients diagnosed with lung cancer., Molecular Biosystems, 11, (3), 2015, p743 - 752Journal Article, 2015
• Barr MP, Bouchier-Hayes DJ, Harmey JJ., Vascular endothelial growth factor is an autocrine survival factor for breast tumour cells under hypoxia., International Journal of Oncology, 32, (1), 2008, p41 - 48Journal Article, 2008
• Barr MP, Byrne AM, Duffy AM, Condron CM, Devocelle M, Harriott P, Bouchier-Hayes DJ, Harmey JH., A peptide corresponding to the neuropilin-1-binding site on VEGF(165) induces apoptosis of neuropilin-1-expressing breast tumour cells., British Journal of Cancer, 92, (2), 2005, p328 - 333Journal Article, 2005
• Pidgeon GP, Barr MP, Harmey JH, Foley DA, Bouchier-Hayes DJ., Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells., British Journal of Cancer, 85, (2), 2001, p273 - 278Journal Article, 2001
• Circu M, Cardelli J, Barr M, O'Byrne K, Mills G, El-Osta H., Modulating lysosomal function through lysosome membrane permeabilization or autophagy suppression restores sensitivity to cisplatin in refractory non-small-cell lung cancer cells., PLoS One, 12, (9), 2017, pe0184922-Journal Article, 2017, DOI , TARA - Full Text
• MacDonagh L, Gray SG, Breen E, Cuffe S, Finn SP, O'Byrne KJ, Barr MP, Exploitation of the vitamin A/retinoic acid axis depletes ALDH1-positive cancer stem cells and re-sensitises resistant non-small cell lung cancer cells to cisplatin., Translational Oncology, 14, (4), 2021, p101025-Journal Article, 2021
• MacDonagh, L. and Gray, S.G. and Breen, E. and Cuffe, S. and Finn, S.P. and O'Byrne, K.J. and Barr, M.P., BBI608 inhibits cancer stemness and reverses cisplatin resistance in NSCLC, Cancer Letters, 428, 2018, p117-126Journal Article, 2018, DOI , URL
• Ryan, S.-L. and Beard, S. and Barr, M.P. and Umezawa, K. and Heavey, S. and Godwin, P. and Gray, S.G. and Cormican, D. and Finn, S.P. and Gately, K.A. and Davies, A.M. and Thompson, E.W. and Richard, D.J. and O'Byrne, K.J. and Adams, M.N. and Baird, A.-M., Targeting NF-KB-mediated inflammatory pathways in cisplatin-resistant NSCLC, Lung Cancer, 135, 2019, p217-227Journal Article, 2019, DOI , URL
• Baird AM, Easty D, Jarzabek M, Shiels L, Soltermann A, Klebe S, Raeppel S, MacDonagh L, Wu C, Griggs K, Kirschner MB, Stanfill B, Nonaka D, Goparaju CM, Murer B, Fennell DA, O'Donnell DM, Barr MP, Mutti L, Reid G, Finn S, Cuffe S, Pass HI, Opitz I, Byrne AT, O'Byrne KJ, Gray SG., When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?, Frontiers in endocrinology, 10, 2019, p89Journal Article, 2019, DOI
• Jiang K, Song C, Kong L, Hu L, Lin G, Ye T, Yao G, Wang Y, Chen H, Cheng W, Barr MP, Liu Q, Zhang G, Ding C, Meng S., Recombinant oncolytic Newcastle disease virus displays antitumor activities in anaplastic thyroid cancer cells., BMC Cancer, 18, (1), 2018, p746Journal Article, 2018, DOI
• Liu M, Jiang K, Lin G, Liu P, Yan Y, Ye T, Yao G, Barr MP, Liang D, Wang Y, Gong P, Meng S, Piao H., Ajuba inhibits hepatocellular carcinoma cell growth via targeting of ß-catenin and YAP signaling and is regulated by E3 ligase Hakai through neddylation., Journal of experimental & clinical cancer research : CR, 37, (1), 2018, p165Journal Article, 2018, DOI
• Ye T, Jiang K, Wei L, Barr MP, Xu Q, Zhang G, Ding C, Meng S, Piao H., Oncolytic Newcastle disease virus induces autophagy-dependent immunogenic cell death in lung cancer cells., American journal of cancer research, 8, (8), 2018, p1514-1527Journal Article, 2018, DOI
• Martin P. Barr, Patient-oriented Biobanking for Cancer Research, Cancer Studies & Therapeutics, 4, (3), 2019, p1 - 2Journal Article, 2019
• Flynn L*, Barr MP*, Baird AM*, Smyth P, Casey OM, Blackshields G, Greene J, Pennington SR, Hams E, Fallon PG, O'Leary JJ, Sheils O, Finn SP. , Prostate cancer-derived holoclones: a novel and effective model for evaluating cancer stemness., Scientific Reports, 10, (1), 2020, p11329-Journal Article, 2020
• Thunnissen E, Kerr KM, Dafni U, Bubendorf L, Finn SP, Soltermann A, Biernat W, Cheney R, Verbeken E, Warth A, Marchetti A, Speel EM, Pokharel S, Quinn AM, Monkhorst K, Navarro A, Madsen LB, Tsourti Z, Geiger T, Kammler R, Peters S, Stahel RA; European Thoracic Oncology Platform Lungscape Consortium., Programmed death-ligand 1 expression influenced by tissue sample size. Scoring based on tissue microarrays' and cross-validation with resections, in patients with, stage I-III, non-small cell lung carcinoma of the European Thoracic Oncology Platform Lungscape cohort., Modern Pathology, 33, (5), 2020, p792 - 801Journal Article, 2020
• Hu L, Shen D, Liang D, Shi J, Song C, Jiang K, Menglin Ren, Du S, Cheng W, Ma J, Li S, Bi X, Barr MP, Fang Z, Xu Q, Li W, Piao H, Meng S., Thyroid receptor-interacting protein 13 and EGFR form a feedforward loop promoting glioblastoma growth., Cancer Letters, 493, 2020, p156 - 166Journal Article, 2020
• MacDonagh L, Gallagher MF, Ffrench B, Gasch C, Gray SG, Reidy M, Nicholson S, Leonard N, Ryan R, Young V, O'Leary JJ, Cuffe S, Finn SP, O'Byrne KJ, Barr MP., MicroRNA expression profiling and biomarker validation in treatment-naïve and drug resistant non-small cell lung cancer., Translational lung cancer research, 10, (4), 2021, p1773-1791Journal Article, 2021, DOI
• Barr M.P., Gray S.G., Gately K., Hams E., Fallon P.G., Davies A.M., Richard D.J., Pidgeon G.P., O'Byrne K.J., Erratum: Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer (Molecular Cancer (2015) DOI: 10.1186/s12943-015-0310-8), Molecular Cancer, 19, (1), 2020Journal Article, 2020, DOI
• Mylod E, McKenna E, Davern M, Barr MP, Donlon NE, Bibby BAS, Bhardwaj A, Reynolds JV, Lysaght J, Maher SG, Conroy MJ, Investigating the susceptibility of treatment-resistant oesophageal tumours to natural killer cell-mediated responses, Clinical and Experimental Medicine, 2022Journal Article, 2022, URL
• Flynn L, Barr MP, Baird AM, Smyth P, Casey OM, Blackshields G, Greene J, Pennington SR, Hams E, Fallon PG, O'Leary J, Sheils O, Finn SP., Prostate cancer-derived holoclones: a novel and effective model for evaluating cancer stemness, SCIENTIFIC REPORTS, 10, 2020, p1132-Journal Article, 2020
• Russell E., M.J. Conroy* and M. Barr*., Harnessing Natural Killer Cells in Non-small Cell Lung Cancer, Cells, 2022Journal Article, 2022, DOI , TARA - Full Text
• Anne-Marie Baird, Martin Barr, Anne-Marie Baird, Sophia Halliday, Petra Martin, Emma H. Allott, James J. Phelan, Greg Korpanty, Linda Coate, Cathal O'Brien, Steven Gray, Jane S. Y. Sui, Brian Hayes, Sinead Cuffe, Stephen Finn, Liquid Biopsy: A Multi-Parametric Analysis of Mutation Status, Circulating Tumor Cells and Inflammatory Markers in EGFR-Mutated NSCLC, Diagnostics, 12, (10), 2022, p2360Journal Article, 2022, DOI
• Ciara S. McNevin, Anna Keogh, Mutaz Mohammed Nur, Brianán McGovern, Julie McFadden, Anne"Marie Baird, Karen A. Cadoo, Sarah Mc Carron, Cathal Ó"Brien, Martin P. Barr, Steven G. Gray, Orla Sheils, Lesley Ann Sutton, Sinéad Flanagan, Lorelei A. Mucci, Konrad H. Stopsack, Stephen P. Finn, Prevalence of Mismatch Repair Deficiency in Primary Prostate Cancer in a Large Prospective Cohort, Clinical Cancer Research, 2025Journal Article, 2025, DOI
• Ciara S. McNevin, Mutaz Mohammed Nur, Cathal Ó"Brien, Brianán McGovern, Julia McFadden, Anne"Marie Baird, Karen A. Cadoo, Martin P. Barr, Steven G. Gray, Anna Keogh, Orla Sheils, Lesley Ann Sutton, Sinéad Flanagan, Lorelei A. Mucci, Konrad H. Stopsack, Stephen P. Finn, Prevalence of mismatch repair deficiency in a large prospective prostate cancer cohort., Journal of Clinical Oncology, 41, (16_suppl), 2023, p5031 - 5031, p5031-5031Journal Article, 2023, DOI
• Sarah-Louise Ryan, Anne"Marie Baird, Zhiliang Lu, Aaron Urquhart, Martin P. Barr, Derek J. Richard, Kenneth J. O"Byrne, Anthony M. Davies, P2.03b-096 Utilization of a Novel 3D Culture Technology for the Assessment of Chemo-Resistance in Non-Small Cell Lung Cancer, Journal of Thoracic Oncology, 12, (1), 2017, pS994 - S995, pS994-S995Journal Article, 2017, DOI
• Sarah-Louise Ryan, P. Godwin, Susan Heavey, Kazuo Umezawa, Martin P. Barr, Steven G. Gray, Bryan Stanfill, Anthony M. Davies, Sinéad Cuffe, Stephen P. Finn, Derek J. Richard, Kathy Gately, Kenneth J. O"Byrne, Anne"Marie Baird, P2.01-031 CCL Chemokines May Play an Important Role in Cisplatin Resistance, Journal of Thoracic Oncology, 12, (1), 2017, pS803 - S804, pS803-S804Journal Article, 2017, DOI
• Anne"Marie Baird, Niamh M. Keegan, Martin P. Barr, Sarah Fishleder, Ahmad Fitri Idris, Emily Harrold, Patrick O"Kelly, Eimear Duff, Sun"Young Lim, M O"Donnell, David Gallagher, Clíona Grant, John Kennedy, D. O"Donnell, S. Sukor, Cathal Ó"Brien, Stephen P. Finn, Sinéad Cuffe, MA 04.10 An Assessment of the Willingness to Provide Serial Bio-Specimens: Experience from an Irish Tertiary Cancer Centre, Journal of Thoracic Oncology, 12, (11), 2017, pS1814 - S1814, pS1814-S1814Journal Article, 2017, DOI
• Anne"Marie Baird, David J. Easty, Monika A. Jarzabek, Liam Shiels, Alex Soltermann, Stéphane Raeppel, Lauren Mcdonagh, Chengguang Wu, Chandra Goparju, Bryan Stanfill, Martin P. Barr, Daisuke Nonaka, Bruno Murer, Dean A. Fennell, D. O"Donnell, Luciano Mutti, Stephen P. Finn, Sinéad Cuffe, Harvey I. Pass, I. Schmitt-Opitz, Annette T. Byrne, Kenneth J. O"Byrne, Steven G. Gray, P3.03-021 When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?, Journal of Thoracic Oncology, 12, (1), 2017, pS1356 - S1357, pS1356-S1357Journal Article, 2017, DOI
• Anne"Marie Baird, Martin P. Barr, Sarah-Louise Ryan, Steven G. Gray, Anthony M. Davies, Sinéad Cuffe, Stephen P. Finn, Derek J. Richard, Kenneth J. O"Byrne, P3.01-042 Lung Cancer Cells Can Stimulate Functional and Genotypic Modifications in Normal Bronchial Epithelial Cells, Journal of Thoracic Oncology, 12, (1), 2017, pS1145 - S1145, pS1145-S1145Journal Article, 2017, DOI
• Joshua T. Burgess, Emma Bolderson, Steven G. Gray, Martin P. Barr, Kathy Gately, Shu"Dong Zhang, Anne"Marie Baird, Derek J. Richard, Kenneth J. O"Byrne, P3.01-064 The Overexpression and Cleavage of SASH1 by Caspase-3 Stimulates Cell Death in Lung Cancer Cells, Journal of Thoracic Oncology, 12, (1), 2017, pS1158 - S1159, pS1158-S1159Journal Article, 2017, DOI
• Yi Mu, Yinan Dong, Mingyang Zheng, Martin P. Barr, Giandomenico Roviello, Zhihuang Hu, Jia Liu, Identification of a prognostic gene signature in patients with cisplatin resistant squamous cell lung cancer, Journal of Thoracic Disease, 16, (7), 2024, p4567 - 4583, p4567-4583Journal Article, 2024, DOI
• Wenping Song, Xuan Wu, Shuai Wang, Martin P. Barr, M. Fernández Rodríguez, In"Jae Oh, Yingxi Wu, Li Ding, Prognostic value and immune regulatory role of dynamin 1-like in lung adenocarcinoma, Translational Lung Cancer Research, 12, (12), 2023, p2476 - 2493, p2476-2493Journal Article, 2023, DOI
• Martin P. Barr, Developing an In Vitro Isogenic Model of Chemotherapy-Resistant Lung Cancer, Methods in molecular biology, 2023, p153 - 163, p153-163Book Chapter, 2023, DOI
• Rachel J. Keogh, Martin P. Barr, Anna Keogh, David McMahon, Cathal Ó"Brien, Stephen P. Finn, Jarushka Naidoo, Genomic Landscape of NSCLC in the Republic of Ireland, JTO Clinical and Research Reports, 5, (2), 2023, p100627 - 100627, p100627-100627Journal Article, 2023, DOI
• Ramesh K. Ganju, Swati Misri, Kirti Kaul, Sanjay Mishra, Manish Charan, Ajeet Kumar Verma, Martin P. Barr, Dinesh K. Ahirwar, Cannabidiol Inhibits Tumorigenesis in Cisplatin-Resistant Non-Small Cell Lung Cancer via TRPV2, Cancers, 14, (5), 2022, p1181 - 1181, p1181-1181Journal Article, 2022, DOI
• Chunfeng Pan, Ke Wei, Zijian Ma, Yaozhou He, Jingjing Huang, Zizhang Guo, Zhipeng Chen, Martin P. Barr, Rodney E. Shackelford, Yang Xia, Jun Wang, CircP4HB regulates ferroptosis via SLC7A11-mediated glutathione synthesis in lung adenocarcinoma, Translational Lung Cancer Research, 11, (3), 2022, p366 - 380, p366-380Journal Article, 2022, DOI
• Martin P. Barr, A-M. Baird, Steven G. Gray, Brian Hayes, Petra Martin, Sophia R. Halliday, Cathal Ó"Brien, Greg Korpanty, Linda Coate, Sinéad Cuffe, Stephen P. Finn, P34.01 Utility of Assessment of the EGFR Resistance Genotype using Cell-Free DNA and CTCs from Liquid Biopsies, Journal of Thoracic Oncology, 16, (3), 2021, pS415 - S415, pS415-S415Journal Article, 2021, DOI
• Changjian Shao, Yuanyong Wang, Minghong Pan, Kai Guo, Tamás Molnár, Florian Kocher, Andreas Seeber, Martin P. Barr, Alfons Navarro, Jing Han, Zhiqiang Ma, Xiaolong Yan, The DNA damage repair-related gene PKMYT1 is a potential biomarker in various malignancies, Translational Lung Cancer Research, 10, (12), 2021, p4600 - 4616, p4600-4616Journal Article, 2021, DOI
• D. Boucher, Nicholas W. Ashton, Amila Suraweera, Joshua T. Burgess, Emma Bolderson, Martin P. Barr, Steven G. Gray, Kathy Gately, Mark N. Adams, Derek J. Richard, Kenneth J. O"Byrne, Human single-stranded DNA protein 1 (hSSB1): a new prognostic tool and target for non-small cell lung cancer treatment, Lung Cancer, 127, 2019, pS3 - S3, pS3-S3Journal Article, 2019, DOI
• Martin P. Barr, https://researchopenworld.com/patient-oriented-biobanking-for-cancer-research/#, Deleted Journal, 4, (3), 2019Journal Article, 2019, DOI
• Martin P. Barr, S. Singh, R Farrell, Emma Foley, Yuexi He, Siobhan Nicholson, Niamh Leonard, Lauren Brady, Sinéad Cuffe, Stephen P. Finn, PO-510 XRCC6BP1: a novel role in the DNA repair of platinum resistant NSCLC cells, ESMO Open, 3, 2018, pA430 - A430, pA430-A430Journal Article, 2018, DOI
• Martin P. Barr, R Farrell, S. Singh, Emma Foley, Yuexi He, Lauren Brady, Vincent Young, Ronan Ryan, Siobhan Nicholson, Niamh Leonard, Sinéad Cuffe, Stephen P. Finn, MA06.09 XRCC6BP1: A DNA Repair Gene in Cisplatin Resistant Lung Cancer Stem Cells That May Predict Survival Outcomes in Patients, Journal of Thoracic Oncology, 13, (10), 2018, pS377 - S377, pS377-S377Journal Article, 2018, DOI
• Martin P. Barr, S. Singh, R Farrell, Emma Foley, Yuexi He, Lauren Brady, Vincent Young, Ronan Ryan, Siobhan Nicholson, Niamh Leonard, Sinéad Cuffe, Stephen P. Finn, P1.02-011 XRCC6BP1: A Key Player in the DNA Repair of Cisplatin Resistant NSCLC Cells, Journal of Thoracic Oncology, 12, (11), 2017, pS1928 - S1928, pS1928-S1928Journal Article, 2017, DOI
• L. Mac Donagh, Stacy W. Gray, Michael Gallagher, Brendan Ffrench, Claudia Gasch, Stephen P. Finn, Sinéad Cuffe, Kenneth J. O"Byrne, Martin P. Barr, P1.03-041 Exploitation of the Cancer Stem Cell Marker ALDH1 Within the Vitamin a/Retinoic Acid Axis Promotes Re-Sensitization of Cisplatin Resistant NSCLC, Journal of Thoracic Oncology, 12, (11), 2017, pS1966 - S1966, pS1966-S1966Journal Article, 2017, DOI
• L. Mac Donagh, Steven G. Gray, Sinéad Cuffe, Stephen P. Finn, Niamh Fitzgerald, Vincent Young, Ronan Ryan, Siobhan Nicholson, Niamh Leonard, Kenneth J. O"Byrne, Martin P. Barr, MA02.02 A Novel 5-miR Signature Shows Promise as a Diagnostic Tool and as a Predictor of Cisplatin Response in NSCLC, Journal of Thoracic Oncology, 12, (1), 2017, pS348 - S349, pS348-S349Journal Article, 2017, DOI
• L. Mac Donagh, Steven G. Gray, Sinéad Cuffe, Stephen P. Finn, Kenneth J. O"Byrne, Martin P. Barr, P2.03a-063 Small Molecule Cancer Stemness Inhibitor, BBI608, Restores Cisplatin Sensitivity in Resistant NSCLC, Journal of Thoracic Oncology, 12, (1), 2017, pS927 - S928, pS927-S928Journal Article, 2017, DOI
• Jane Sze Yin Sui, Min Yuen Teo, Shereen Rafee, Julie Mc Fadden, Kathy Gately, Martin P. Barr, Steven G. Gray, Sinéad Cuffe, Stephen P. Finn, P2.01-066 PD-L1 Tumor Expression and Its Effect on Overall Survival among Patients with Resected Non-Small Cell Lung Cancer (NSCLC), Journal of Thoracic Oncology, 12, (1), 2017, pS827 - S827, pS827-S827Journal Article, 2017, DOI
• L. Mac Donagh, Steven G. Gray, Stephen P. Finn, Sinéad Cuffe, Michael Gallagher, Kenneth J. O"Byrne, Martin P. Barr, P2.03a-064 Inhibition and Exploitation of Aldehyde Dehydrogenase 1 as a Cancer Stem Cell Marker to Overcome Cisplatin Resistant NSCLC, Journal of Thoracic Oncology, 12, (1), 2017, pS928 - S928, pS928-S928Journal Article, 2017, DOI
• Martin P. Barr, S. Singh, Emma Foley, Yuexi He, Vincent Young, Ronan Ryan, Siobhan Nicholson, Niamh Leonard, Sinéad Cuffe, Kenneth J. O"Byrne, Stephen P. Finn, P2.03a-062 Characterization and Targeting of the DNA Repair Gene, XRCC6BP1, in Cisplatin Resistant NSCLC, Journal of Thoracic Oncology, 12, (1), 2017, pS926 - S927, pS926-S927Journal Article, 2017, DOI
• Jane Sze Yin Sui, Min Yuen Teo, Sinéad Toomey, Shereen Rafee, Julia McFadden, Kathy Gately, Martin P. Barr, Steven G. Gray, Bryan T. Hennessy, Kenneth J. O"Byrne, Sinéad Cuffe, Stephen P. Finn, Impact and correlation of mutational load (ML) and specific mutations (mts) assessed by limited targeted profiling (LTP) with PD-L1 tumour expression (exp) in resected non-small cell lung carcinoma (NSCLC)., Journal of Clinical Oncology, 35, (15_suppl), 2017, p11587 - 11587, p11587-11587Journal Article, 2017, DOI
• Steven G. Gray, A-M. Baird, David J. Easty, Monika A. Jarzabek, Liam Shiels, Chengguang Wu, Alex Soltermann, Stéphane Raeppel, Lauren MacDonagh, M. Melovic, H. Lambkin, Bryan Stanfill, Daisuke Nonaka, Chandra Goparju, Bruno Murer, D. O"Donnell, Luciano Mutti, Martin P. Barr, Stephen P. Finn, Sinéad Cuffe, Harvey I. Pass, Kenneth J. O"Byrne, I. Schmitt-Opitz, Annette T. Byrne, P1.09-007 Targeting MET/TAM Receptors in Mesothelioma: Are Multi-TKIs Superior to Specific TKI?, Journal of Thoracic Oncology, 12, (11), 2017, pS2020 - S2020, pS2020-S2020Journal Article, 2017, DOI
• L. Mac Donagh, Steven G. Gray, Stephen P. Finn, Sinéad Cuffe, Kenneth J. O"Byrne, Martin P. Barr, P1.03-042 BBI608, a Small Molecule Stemness Inhibitor, Circumvents Cisplatin Resistance in NSCLC, Journal of Thoracic Oncology, 12, (11), 2017, pS1966 - S1967, pS1966-S1967Journal Article, 2017, DOI
• Martin P. Barr, Graham P. Pidgeon, Steven G. Gray, Kathy Gately, Emily Hams, Padraic G. Fallon, Sinéad Cuffe, Stephen P. Finn, Kenneth J. O"Byrne, P2.02-069 Targeting Neuropilin-1 in NSCLC, Journal of Thoracic Oncology, 12, (11), 2017, pS2125 - S2125, pS2125-S2125Journal Article, 2017, DOI
• L. Mac Donagh, Steven G. Gray, Michael Gallagher, Brendan Ffrench, Claudia Gasch, Stephen P. Finn, Sinéad Cuffe, Kenneth J. O"Byrne, Martin P. Barr, P1.03-048 miR-34a and the Micromanagement of Cancer Stemness and Resistance in NSCLC. Does It Hold Therapeutic Benefit?, Journal of Thoracic Oncology, 12, (11), 2017, pS1969 - S1969, pS1969-S1969Journal Article, 2017, DOI
• L. Mac Donagh, Steven G. Gray, Sinéad Cuffe, Stephen P. Finn, S. Nicholson, Ronan Ryan, Vincent Young, Niamh Leonard, Kenneth J. O"Byrne, Martin P. Barr, P1.03-039 Therapeutic Inhibition of the Cancer Stem Cell Marker, ALDH1, a Promising Mechanism by Which Cisplatin Sensitivity Can Be Restored in NSCLC, Journal of Thoracic Oncology, 12, (11), 2017, pS1965 - S1965, pS1965-S1965Journal Article, 2017, DOI
• L. Mac Donagh, Steven G. Gray, Michael Gallagher, Brendan Ffrench, Claudia Gasch, Vincent Young, Ronan Ryan, Siobhan Nicholson, Niamh Leonard, Stephen P. Finn, Sinéad Cuffe, Kenneth J. O"Byrne, Martin P. Barr, P2.02-064 A Novel 5-miR Signature Shows Potential as a Diagnostic Tool and as a Predictive Biomarker of Cisplatin Response in NSCLC, Journal of Thoracic Oncology, 12, (11), 2017, pS2123 - S2123, pS2123-S2123Journal Article, 2017, DOI
• Magdalena L. Circu, James A. Cardelli, Martin P. Barr, Hazem El"Osta, Abstract 3537: Cisplatin refractory lung cancer cells exhibit an increased autophagic flux at baseline and following exposure to cisplatin, Cancer Research, 76, (14_Supplement), 2016, p3537 - 3537, p3537-3537Journal Article, 2016, DOI
• Magdalena L. Circu, James A. Cardelli, Glenn Mills, Martin P. Barr, Hazem El"Osta, Abstract 3511: Chloroquine-induced lysosomal membrane permeabilization restores sensitivity to cisplatin in refractory lung cancer cells, Cancer Research, 76, (14_Supplement), 2016, p3511 - 3511, p3511-3511Journal Article, 2016, DOI
• Susan Heavey, Sinéad Toomey, Aoife Carr, Sinéad Cuffe, Stephen P. Finn, Bryan T. Hennessy, John Crown, Martin P. Barr, Kenneth J. O"Byrne, Kathy Gately, Abstract B25: PI3K targeted inhibition in NSCLC: An in vitro evaluation and correlation of mutation status to activated PI3K pathway signaling in NSCLC patients, Molecular Cancer Therapeutics, 14, (7_Supplement), 2015, pB25 - B25, pB25-B25Journal Article, 2015, DOI
• Susan Heavey, Martin P. Barr, Anthony M. Davies, Kenneth J. O"Byrne, Kathy Gately, Abstract B25: The Effects of PI3K/Akt/mTOR Pathway Inhibitors on a Panel of Non Small Cell Lung Cancer (NSCLC) Cell Lines, Clinical Cancer Research, 18, (10_Supplement), 2012, pB25 - B25, pB25-B25Journal Article, 2012, DOI
• Susan Heavey, Martin P. Barr, P. Godwin, Connla Edwards, Kenneth J. O"Byrne, Kathy Gately, Abstract A64: NF"B-I"B" Interaction: A Mechanism of Resistance to Cisplatin in Non Small Cell Lung Cancer (NSCLC), Clinical Cancer Research, 18, (10_Supplement), 2012, pA64 - A64, pA64-A64Journal Article, 2012, DOI
• Susan Heavey, Martin P. Barr, Afza Ahmad, A. Davies, Kenneth J. O"Byrne, Kathy Gately, Co-Targeting The PI3K-MTOR & MEK Pathways in NSCLC, Annals of Oncology, 23, 2012, pix69 - ix70, pix69-ix70Journal Article, 2012, DOI
• Kathy Gately, Susan Heavey, P. Godwin, Martin P. Barr, Kenneth J. O"Byrne, Targeting NFKB in Cisplatin Resistant NSCLC, Annals of Oncology, 23, 2012, pix68 - ix68, pix68-ix68Journal Article, 2012, DOI
• Kathy Gately, Elizabeth Jennions, P. Godwin, Martin P. Barr, Susan Heavey, Kazuo Umezawa, John Edwards, Steven G. Gray, Kenneth J. O"Byrne, Nuclear Factor-Kappa B as a Molecular Target in Malignant Pleural Mesothelioma, Annals of Oncology, 23, 2012, pix495 - ix495, pix495-ix495Journal Article, 2012, DOI
• Steven G. Gray, Dean A. Fennell, John O"Leary, Derek J. Richard, Jüergen Thomale, Andreas-Claudius Hoffmann, Kenneth J. O"Byrne, Martin P. Barr, Microrna Profiling and CDDP-GPG DNA Adduct Formation Analysis in a Panel of Cisplatin Resistant Non-Small Cell Lung Cancer Cell Lines, Annals of Oncology, 23, 2012, pix68 - ix68, pix68-ix68Journal Article, 2012, DOI
• Graham P. Pidgeon, Martin P. Barr, Kathy Gately, Joanne Lysaght, John V. Reynolds, Elaine W. Kay, Kenneth J. O"Byrne, P2-050: Blockade of neuropilin-1 decreases NSCLC survival by regulating angiogenic and apoptotic gene expression, Journal of Thoracic Oncology, 2, (8), 2007, pS510 - S510, pS510-S510Journal Article, 2007, DOI
• Graham P. Pidgeon, Martin P. Barr, Mary"Clare Cathcart, Kenneth J. O"Byrne, Neuropilin-1 regulates tumor cell survival in lung cancer cell lines under serum depleted conditions, Cancer Research, 65, 2005, p185 - 186, p185-186Journal Article, 2005
• Field JK, Liloglou T, Niaz A, Bryan J, Gosney JR, Giles T, Brambilla C, Brambilla E, Vesin A, Timsit JF, Hainaut P, Martinet Y, Vignaud JM, Thunnissen FB, Prinsen C, Snijders PJ, Smit EF, Sozzi G, Roz L, Risch A, Becker HD, Elborn JS, Magee ND, Montuenga LM, Pajares MJ, Lozano MD, O'Byrne KJ, Harrison DJ, Niklinski J, Cassidy A, EUELC project: a multi-centre, multipurpose study to investigate early stage NSCLC, and to establish a biobank for ongoing collaboration., The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology, 34, (6), 2009, p1477-86Journal Article, 2009, DOI
• O'Byrne KJ, Barr MP, Gray SG., The role of epigenetics in resistance to cisplatin chemotherapy in lung cancer, Cancers, 3, (1), 2011, p1426 - 1453Journal Article, 2011, DOI , URL , TARA - Full Text
• KJ O'Byrne, The Role of Epigenetics in Resistance to Cisplatin Chemotherapy in Lung Cancer, Cancers , 3, (1), 2011, p1426-1453Journal Article, 2011, DOI , URL , TARA - Full Text
• O'Flaherty JD, Barr M, Fennell D, Richard D, Reynolds J, O'Leary J, O'Byrne K, The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy., Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 7, (12), 2012, p1880-90Journal Article, 2012, DOI
• Barr MP, Gray SG, Hoffmann AC, Hilger RA, Thomale J, O'Flaherty JD, Fennell DA, Richard D, O'Leary JJ, O'Byrne KJ., Generation and characterisation of Cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature., PloS one, 8, (1), 2013, pe54193Journal Article, 2013, DOI , URL , TARA - Full Text
• Barr M, Souan L, MacGabhann P, Muller J, Al-Ashhab M, Jasser M, Hamza K, Al-Hassoon S, Kuhn U, Infante D, Lawlor D, Kately K, Amireh E, O'Byrne K, Sughayer MA., The establishment of an ISO compliant cancer biobank for Jordan and its neighboring countries through knowledge transfer and training., Biopreservation and biobanking, 12, (1), 2014, p3-12Journal Article, 2014, DOI , TARA - Full Text
• Godwin P, Baird AM, Heavey S, Barr MP, O'Byrne KJ, Gately K., Targeting nuclear factor-kappa B to overcome resistance to chemotherapy., Frontiers in oncology, 3, 2013, p120Journal Article, 2013, DOI , TARA - Full Text

• Martin P. Barr, Lung Cancer Screening: is Ireland ready?, 7, 2, Medical Independent, Medical Independent, July, 2021, p20 - 22Report

Cancer,

• Member of the Irish Association for Cancer Research (IACR).
• Member of Council of the Irish Association of Clinical Scientists (IACS).
• Member of the International Association for the Study of Lung Cancer (IASLC).
• Fellow of the Institute of Biomedical Science UK (IBMS).
• Member of Clinical Trials Ireland (CTI).
• Chartered Scientist (Science Council, UK).
• Member of the Health Research Board-Clinical Research Coordination Ireland (HRB-CRCI).
• Member & Ambassador of the European Association for Cancer Research (EACR).
• Member of the Irish Thoracic Society (ITS).
• Member of the European Respiratory Society (ERS).
• Member of the Irish Platform for Patients' Organisations, Science and Industry (IPPOSI).
• Member (Associate) of the European Society for Medical Oncology (ESMO).
• Member of the National Standards Authority of Ireland (NSAI)- National Mirror Committee for Biobanking Standards in Ireland (ISO 20387).
• Member of the Academy of Clinical Science & Laboratory Medicine (ACSLM).
• Irish Lung Cancer Alliance (ILCA).