Dr. Sharon O'Toole

• The Use of MYBL2 as a Novel Candidate Biomarker of Cervical Cancer. in, editor(s)Daniel Keppler Athena W. Lin , Cervical Cancer. Methods in Molecular Biology, Springer New York, 2015, pp241 - 251, [Martin CM, Astbury K, Kehoe L, O'Crowley JB, O'Toole S, O'Leary JJ. ]Book Chapter, 2015, DOI
• Noninvasive Biomarkers in Ovarian Cancer in, editor(s)Debmalya Barh, Angelo Carpi, Mukesh Verma, Mehmet Gunduz , Cancer Biomarkers: Minimal and Noninvasive Early Diagnosis and Prognosis , CRC press, 2014, [O'Toole, SA, Ancuta, E, Langhe, R, Cahill, DJ, Murphy, M, Martin, C, McEvoy, L, Spillane, C, Sheils, O, Petricoin, E, Liotta, L, O'Leary JJ]Book Chapter, 2014
• Martin CM, Astbury K, Kehoe L, O'Crowley JB, O'Toole S, O'Leary JJ. , The Use of MYBL2 as a Novel Candidate Biomarker of Cervical Cancer. , Methods Mol Biol, 1249, 2015, p241 - 251Journal Article, 2015
• Busschots S, O'Toole S, O'Leary JJ, Stordal B, Non-invasive and non-destructive measurements of confluence in cultured adherent cell lines., MethodsX, 2, 2015, p8-13Journal Article, 2015
• McEvoy LM, O'Toole SA, Spillane CD, Martin CM, Gallagher MF, Stordal B, Blackshields G, Sheils O, O'Leary JJ, Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer., BMC cancer, 15, 2015, p547Journal Article, 2015
• Abu Saadeh, F, Langhe R, Galvin DM, O Toole SA, O'Donnell DM, Gleeson N, Norris LA, Procoagulant activity in gynaecological cancer patients; the effect of surgery and chemotherapy. , Thrombosis Research, 139, 2016, p135 - 141Journal Article, 2016, DOI
• O'Toole SA, Dunn E, Sheppard BL, Sheils O, O'Leary JJ, Wuttke W, Seidlova-Wuttke, D, Oestrogen regulated gene expression in normal and malignant endometrial tissue. , Maturitas, 51, (2), 2005, p187 - 198Journal Article, 2005, URL
• O'Toole SA, Sheppard BL, Sheils O, O'Leary JJ, Spengler B, Christoffel V. , Analysis of DNA in endometrial cancer cells treated with phyto-estrogenic compounds using comparative genomic hybridisation microarrays., Planta Medica, 71, (5), 2005, p435 - 439Journal Article, 2005, URL
• Petch S, Norris L, O'Toole S, Gleeson N, Abu Saadeh F. , Peri operative venous thromboembolism prophylaxis in gynaecological cancer patients. A survey of current practice., Thrombosis Research, 145, 2016, p126 - 128Journal Article, 2016, DOI
• White C, Bakhiet S, Bates M, Keegan H, Pilkington L, Ruttle C, Sharp L, O' Toole S, Fitzpatrick M, Flannelly G, O' Leary JJ, Martin CM. , Triage of LSIL/ASC-US with p16/Ki-67 dual staining and human papillomavirus testing: a 2-year prospective study. , Cytopathology, 27, (4), 2016, p269 - 276Journal Article, 2016, DOI
• Ffrench B, Gasch, Hokamp K, Spillane C, Blackshields G, Mahgoub TM, Bates M, Kehoe L, Mooney A, Doyle R, Doyle B, O'Donnell D, Gleeson N, Hennessy BT, Stordal B, O'Riain C, Lambkin H, O'Toole S, O'Leary JJ, and Gallagher MF., CD10-/ALDH- cells are the sole cisplatin-resistant component of a novel ovarian cancer stem cell network. Cell Death & Disease , Cell Death and Disease, 8, (10), 2017, e3128Journal Article, 2017, TARA - Full Text
• B Jose, S O'Toole, R Forster, JJ O'Leary. , Smart Nanomotors: Towards in-vivo Sensing., Laboratory Investigation , USCAP, 97, ((S1)), 2017, pp530A-Published Abstract, 2017
• Ffrench B, Gasch C, Hokamp K, Spillane C, Blackshields G, Mahgoub TM, Bates M, Kehoe L, Mooney A, Doyle R, Doyle B, O'Donnell D, Gleeson N, Hennessy BT, Stordal B, O'Riain C, Lambkin H, O'Toole S, O'Leary JJ, Gallagher MF., CD10(-)/ALDH(-) cells are the sole cisplatin-resistant component of a novel ovarian cancer stem cell hierarchy., Cell Death Disease, 19, (8), 2017, pe3128-Journal Article, 2017, DOI
• O'Toole SA, Dunn E, Sheppard BL, Klocker H, Bektic J, Smyth P, Martin C, Sheils O, O'Leary JJ., Genome wide analysis of DNA in endometrial cancer using comparative genomic hybridisation microarrays. , International Journal of Gynaecological Cancer , 16, (2), 2006, p834 - 842Journal Article, 2006, URL
• (ed.), Predicting the response of gynaecological tumours to chemotherapy. , 24, (2A), 2004, 533 - 534 pProceedings of a Conference, 2004
• Z. Marchocki, N. Gleeson, F. Abu Saadeh, M.P. Ward, S.A. O'Toole, L.A. Norris, Fibrinogen, D-Dimers and thrombin generation assays as predictors of the risk of recurrent VTE in patients with gynaecological malignancies, Thrombosis Research, International Congress on Thrombosis and Haemostasis Issues in Cancer, Bergamo, April 2018, 164, (Supplement 1), 2018, pp200 - 200Meeting Abstract, 2018, DOI
• Z. Marchocki, L.N. Norris, S.A. O'Toole, N. Gleeson, F. Abu Saadeh S235, Patients experience and compliance with extended LMWH prophylaxis post-surgery for gynaecological cancer, Thrombosis Research, International Congress on Thrombosis and Haemostasis Issues in Cancer, Bergamo, April 2018, 164, (Supplement 1), Elsevier, 2018, ppS235 - S235Published Abstract, 2018, DOI
• Tewari P, White C, Kelly L, Pilkington L, Keegan H, D'Arcy T, Toole SO, Sharp L, O'Leary JJ, Martin CM., Clinical performance of the Cobas 4800 HPV test and the Aptima HPV assay in the management of women referred to colposcopy with minor cytological abnormalities., Diagnostic cytopathology, 46, (12), 2018, p987-992Journal Article, 2018, DOI
• Ward MP, Abu Saadeh, F, O'Toole S, Marchocki Z, Gleeson N, Norris LA, Optimisation of Thrombin Generation as a Predictive Biomarker for Venous Thromboembolism in Gynaecological Malignancies, Research Practice in Thrombosis and Haemostasis, International Society for Thrombosis and Haemostasis, Dublin, July 2018, 2, (Supplement 1), Wiley, 2018, ppPB518 - PB518Published Abstract, 2018, DOI
• Marchocki Z, Norris L, O'Toole S, Gleeson N, Abu Saadeh F, Patients' experience and compliance with extended low molecular weight heparin prophylaxis post-surgery for gynaecological cancer. A prospective observational study, International Journal of Gynaecological Cancer. , 2019Journal Article, 2019, DOI
• B Mohamed, S O'Toole, S Elbaruni, L Norris, F AbuSaadeh, S Gray, J. O'Leary , EP926 PAD enzymes as a candidate therapeutic target in ovarian cancer, International Journal of Gynaecological Cancer, 29, ((Supplement 4)), 2019, ppA497 - A497Published Abstract, 2019, DOI
• Cluxton, C.D. and Spillane, C. and O†Toole, S.A. and Sheils, O. and Gardiner, C.M. and O†Leary, J.J., Suppression of Natural Killer cell NKG2D and CD226 anti-tumour cascades by platelet cloaked cancer cells: Implications for the metastatic cascade, PLoS ONE, 14, (3), 2019Journal Article, 2019, DOI , TARA - Full Text
• O'Toole SA, Spillane C, Huang Y, Fitzgerald MC, Ffrench B, Mohamed B, Ward M, Gallagher M, Kelly T, O'Brien C, Ruttle C, Bogdanska A, Martin C, Mullen D, Connolly E, McGarrigle SA, Kennedy J, O'Leary JJ., Circulating tumour cell enumeration does not correlate with Miller-Payne grade in a cohort of breast cancer patients undergoing neoadjuvant chemotherapy., Breast cancer research and treatment, 181, (3), 2020, p571-580Journal Article, 2020, DOI
• Norris LA, Ward MP, O'Toole SA, Marchocki Z, Ibrahim N, Khashan AS, Abu Saadeh F, Gleeson N., A risk score for prediction of venous thromboembolism in gynecologic cancer: The Thrombogyn score., Res Pract Thromb Haemost, 4, (5), 2020, p848-859Journal Article, 2020, DOI
• Liong S, Oseghale O, To EE, Brassington K, Erlich JR, Luong R, Liong F, Brooks R, Martin C, O'Toole S, Vinh A, O'Neill LAJ, Bozinovski S, Vlahos R, Papagianis PC, O'Leary JJ, Brooks DA, Selemidis S., Influenza A virus causes maternal and fetal pathology via innate and adaptive vascular inflammation in mice., Proceedings of the National Academy of Sciences of the United States of America, 2020Journal Article, 2020, DOI , TARA - Full Text
• White, Christine M., Bakhiet, Salih, Bates, Mark, Ruttle, Carmel, Pilkington, Loretto J., Keegan, Helen, O"Toole, Sharon A., Sharp, Linda, O"Kelly, Ruth, Tewari, Prerna, Flannelly, Grainne, Martin, Cara M., O"Leary, John J., Exposure to tobacco smoke measured by urinary nicotine metabolites increases risk of p16/Ki-67 co-expression and high-grade cervical neoplasia in HPV positive women: A two year prospective study, Cancer Epidemiology, 68, 2020, p101793Journal Article, 2020, DOI
• McKendry, Kate, Duff, Stephen, Huang, Yanmei, Redha, Mostafa, Scanlon, Áine, Abu Saadeh, Feras, Gleeson, Noreen, O"Leary, John, Norris, Lucy, O"Toole, Sharon, The value of HE4, D"dimer, and fibrinogen compared to CA125 alone in triaging women presenting with pelvic masses: a retrospective cohort study, Acta Obstetricia et Gynecologica Scandinavica, 2021Journal Article, 2021, DOI
• Kane, L.E., Ward, M.P., Norris, L.A et al., Platelets, immune cells and the coagulation cascade; friend or foe of the circulating tumour cell?, Molecular Cancer, 20, 2021, p59-Journal Article, 2021, DOI
• Martin F, Long JC, O'Toole SA, O'Leary JJ, Abu Saadeh F, Gleeson N, Norris LA., PO-14 - Tumour expression of coagulation proteases of the aPC pathway - a role in the pathogenesis of gynaecological cancers?, Thrombosis research, 140 Suppl 1, 2016, pS181Journal Article, 2016, DOI
• Riccardo Di Fiore, Sherif Suleiman, Ana Felix, Sharon A O'Toole, John J O'Leary, Mark P Ward, James Beirne, Maja Sabol, Petar Ozretić, Angel Yordanov, Mariela Vasileva-Slaveva, Stoyan Kostov, Margarita Nikolova, Ian Said-Huntingford, Duncan Ayers, Bridget Ellul, Francesca Pentimalli, Antonio Giordano, Jean Calleja-Agius, An Overview of the Role of Long Non-Coding RNAs in Human Choriocarcinoma, International Journal of Molecular Sciences, 22, 2021Journal Article, 2021, DOI
• Bates M, Spillane CD, Gallagher MF, McCann A, Martin C, Blackshields G, Keegan H, Gubbins L, Brooks R, Brooks D, Selemidis S, O'Toole S, O'Leary JJ., The role of the MAD2-TLR4-MyD88 axis in paclitaxel resistance in ovarian cancer., PloS one, 15, (12), 2020, pe0243715Journal Article, 2020, DOI
• Di Fiore R, Suleiman S, Drago-Ferrante R, Felix A, O'Toole SA, O'Leary JJ, Ward MP, Beirne J, Yordanov A, Vasileva-Slaveva M, Subbannayya Y, Pentimalli F, Giordano A, Calleja-Agius J., LncRNA MORT (ZNF667-AS1) in Cancer-Is There a Possible Role in Gynecological Malignancies?, International journal of molecular sciences, 22, (15), 2021Journal Article, 2021, DOI
• Tewari P, Banka P, Kernan N, Reynolds S, White C, Pilkington L, O'Toole S, Sharp L, D'Arcy T, Murphy C, Comiskey C, Martin CM, O'Leary JJ., Prevalence and concordance of oral HPV infections with cervical HPV infections in women referred to colposcopy with abnormal cytology., Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 50, (7), 2021, p692-699Journal Article, 2021, DOI
• Spillane CD, Cooke NM, Ward MP, Kenny D, Blackshields G, Kelly T, Bates M, Huang Y, Martin C, Skehan S, Canney A, Gallagher M, Smyth P, Brady N, Clarke A, Mohamed B, Norris L, Brooks DA, Brooks RD, Heatlie JK, Selemidis S, Hanniffy S, Dixon E, Sheils O, O'Toole SA, O'Leary JJ., The induction of a mesenchymal phenotype by platelet cloaking of cancer cells is a universal phenomenon., Translational oncology, 14, (12), 2021, p101229Journal Article, 2021, DOI
• Abu Saadeh F, Marchocki Z, O'Toole SA, Ibrahim N, Gleeson N, Norris LA., Extended thromboprophylaxis post gynaecological cancer surgery; the effect of weight adjusted and fixed dose LMWH (Tinzaparin)., Thrombosis Research, 207, 2021, p25 - 32Journal Article, 2021, DOI
• Oseghale O, Liong S, Coward-Smith M, To EE, Erlich JR, Luong R, Liong F, Miles M, Norouzi S, Martin C, O'Toole S, Brooks RD, Bozinovski S, Vlahos R, O'Leary JJ, Brooks DA, Selemidis S., Influenza A virus elicits peri-vascular adipose tissue inflammation and vascular dysfunction of the aorta in pregnant mice., PLoS pathogens, 18, (8), 2022, pe1010703Journal Article, 2022, DOI
• Mohamed BM, Ward MP, Bates M, Spillane CD, Kelly T, Martin C, Gallagher M, Heffernan S, Norris L, Kennedy J, Saadeh FA, Gleeson N, Brooks DA, Brooks RD, Selemidis S, O'Toole S, O'Leary JJ., Ex vivo expansion of circulating tumour cells (CTCs)., Scientific reports, 13, (1), 2023, p3704 - 3704Journal Article, 2023, DOI
• Batog, WI, Maguire P, O'Toole SA, Norris L, Abu Saadeh F, Identification of groin node metastasis in squamous vulval cancer using pre-operative [18F] FDG-PET/CT. Can unnecessary lymphadectomy be prevented?, International Journal of Gynaecological Cancer, European Society for Gynaecological Oncology, Berlin, October 2022, 32, (Supplement 2), 2022, pp1590 - 1590Conference Paper, 2022
• Ward MP, O'Toole SA, Abu Saadeh F, Marchocki Z, Ibrahim EM, Martin F, Gleeon N, O'leary JJ, Norris LA, Mechanisms of cancer associated thrombosis in gynaecological cancer patients- tumour or treatment effect?, Research Practice in Thrombosis and Haemostasis, International Society for Thrombosis and Haemostasis, London, July 2022, 6, (Supplement 2), Wiley, 2022, ppPB0752 - PB0752Conference Paper, 2022, URL
• Di Fiore R, Suleiman S, Ellul B, O'Toole SA, Savona-Ventura C, Felix A, Napolioni V, Conlon NT, Kahramanoglu I, Azzopardi MJ, Dalmas M, Calleja N, Brincat MR, Muscat-Baron Y, Sabol M, Dimitrievska V, Dimitrievska V, Yordanov A, Vasileva-Slaveva M, von Brockdorff K, Micallef RA, Kubelac P, Achima"-Cadariu P, Vlad C, Tzortzatou O, Poka R, Giordano A, Felice A, Reed N, Herrington CS, Faraggi D, Faraggi D, Calleja-Agius J., GYNOCARE Update: Modern Strategies to Improve Diagnosis and Treatment of Rare Gynecologic Tumors"Current Challenges and Future Directions , Cancers, 13, (3), 2021, p493Journal Article, 2021, DOI
• Ali A, Zhang F, Maguire A, Byrne T, Weiner-Gorzel K, Bridgett S, O'Toole S, O'Leary J, Beggan C, Fitzpatrick P, McCann A, Furlong F., HDAC6 Degradation Inhibits the Growth of High-Grade Serous Ovarian Cancer Cells. , Cancers, 12, (12), 2020, pE3734Journal Article, 2020, DOI
• O'Sullivan L, Carroll TP, Clarke N, Cooper S, Cullen A, Gorman L, McCann B, Mee B, Miller N, Murphy V, Murray M, O'Leary J, O'Toole S, Snapes E, Bracken S., Harmonising the human biobanking consent process: an Irish experience. , HRB Open Res, 4, 2021, p96Journal Article, 2021, DOI
• Lazniewska J, Li KL, Johnson IRD, Sorvina A, Logan JM, Martini C, Moore C, Ung BS, Karageorgos L, Hickey SM, Prabhakaran S, Heatlie JK, Brooks RD, Huzzell C, Warnock NI, Ward MP, Mohammed B, Tewari P, Martin C, O'Toole S, Edgerton LB, Bates M, Moretti P, Pitson SM, Selemidis S, Butler LM, O'Leary JJ, Brooks DA., Dynamic interplay between sortilin and syndecan-1 contributes to prostate cancer progression., Scientific reports, 13, (1), 2023, p13489Journal Article, 2023, DOI
• Ward, Mark P, Lewis, Faye, O'Gorman, Catherine, Kelly, Tanya E, Mohamed, Bashir M, Henderson, Brian, Hurley, Sinead, O'Connor, Roisin, Brooks, Robert D, Brooks, Doug A, Selemidis, Stavros, Maguire, Patrick, Kamran, Waseem, Beirne, James P, Saadeh, Feras A, Cadoo, Karen, Norris, Lucy A, Martin, Cara, O'Toole, Sharon A, O'Leary, John J, #836 Liquid biopsy isolation of circulating tumour cells from epithelial ovarian cancer patients and their prognostic significance, European Congress on Gynaecological Oncology, Istanbul, Turkey, BMJ Publishing Group Ltd, 2023Conference Paper, 2023, DOI
• Kelly TE, Spillane CL, Ward MP, Hokamp K, Huang Y, Tewari P, Martin CM, Norris LA, Mohamed BM, Bates M, Brooks R, Selemidis S, Brooks DA, Kamran W, Saadeh FA, O'Toole SA, O'Leary JJ., Plasminogen activator inhibitor 1 is associated with high-grade serous ovarian cancer metastasis and is reduced in patients who have received neoadjuvant chemotherapy., Frontiers in cell and developmental biology, 11, 2023, p1150991Journal Article, 2023, DOI
• M Saini, Volga, Oner, Ezgi, Ward, Mark P., Hurley, Sinead, Henderson, Brian David, Lewis, Faye, Finn, Stephen P., Fitzmaurice, Gerard J., O'Leary, John J., O'Toole, Sharon, O'Driscoll, Lorraine, Gately, Kathy, A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer, Molecular Oncology, 2024Journal Article, 2024, DOI
• M Saini, Volga, Oner, Ezgi, Ward, Mark P., Hurley, Sinead, Henderson, Brian David, Lewis, Faye, Finn, Stephen P., Fitzmaurice, Gerard J., O'Leary, John J., O'Toole, Sharon, O'Driscoll, Lorraine, Gately, Kathy, A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer, Molecular Oncology, 2024Journal Article, 2024, DOI
• LEWIS, F., BEIRNE, J., HENDERSON, B., NORRIS, L., CADOO, K., KELLY, T., MARTIN, C., HURLEY, S., KANJUGA, M., O'DRISCOLL, L., GATELY, K., ONER, E., SAINI, V. M., BROOKS, D., SELEMIDIS, S., KAMRAN, W., HAUGHEY, N., MAGUIRE, P., O'GORMAN, C., SAADEH, F. A., WARD, M. P., O'LEARY, J. J. & O'TOOLE, S. A., Unravelling the biological and clinical challenges of circulating tumour cells in epithelial ovarian carcinoma, Cancer Letters, 2024Journal Article, 2024, DOI
• LEWIS, F., WARD, M. P., SAADEH, F. A., O'GORMAN, C., MAGUIRE, P. J., BEIRNE, J. P., KAMRAN, W., IBRAHIM, E., NORRIS, L., KELLY, T., HURLEY, S., HENDERSON, B., KANJUGA, M., O'DRISCOLL, L., GATELY, K., ONER, E., SAINI, V. M., CADOO, K., MARTIN, C., O'LEARY, J. J. & O'TOOLE, S. A., A pilot study evaluating the feasibility of enriching and detecting circulating tumour cells from peripheral and ovarian veins in rare epithelial ovarian carcinomas, European Journal of Surgical Oncology, 2025Journal Article, 2025, DOI
• LEWIS, F., WARD, M. P., SAADEH, F. A., O'GORMAN, C., MAGUIRE, P. J., BEIRNE, J. P., KAMRAN, W., IBRAHIM, E., NORRIS, L., KELLY, T., HURLEY, S., HENDERSON, B., KANJUGA, M., O'DRISCOLL, L., GATELY, K., ONER, E., SAINI, V. M., CADOO, K., MARTIN, C., O'LEARY, J. J. & O'TOOLE, S. A., A pilot study evaluating the feasibility of enriching and detecting circulating tumour cells from peripheral and ovarian veins in rare epithelial ovarian carcinomas, European Journal of Surgical Oncology, 2025Journal Article, 2025, DOI
• Batog WI, Norris L, O'Toole S, Maguire P, O'Gorman C, Kelly M, Saadeh FA., Identification of groin node metastasis in squamous cell vulval cancer using preoperative [¹⁸F] FDG-PET/CT. Can unnecessary lymphadenectomy be prevented?, European journal of obstetrics, gynecology, and reproductive biology, 310, 2025, p113959Journal Article, 2025, DOI
• Mark P. Ward and Bashir M. Mohamed and Laura Kane and Mark Bates and Janina Berghoff and Cathy L. Spillane and Tanya Kelly and John Kennedy and Feras A. Saadeh and Karsten Hokamp and Noreen Gleeson and Orla Sheils and Cara Martin and Michael Gallagher and Sean Hannify and Eric P. Dixon and Sharon A. O{\textquotesingle, Abstract 764: Influence of platelets and neutrophils on circulating tumour cells, Clinical Research (Excluding Clinical Trials), 2020Journal Article, 2020, DOI
• White, Christine and Reynolds, Stephen and Murphy, Katherine and Keegan, Helen and Naik, Padma and O'Brien, Roisin and Pilkington, Loretto and Sharkey Ochoa, Imogen and Glesson, Grainne and Russell, Noirin and Nuttall, David and Tewari, Prerna and Wright, Fiona and O'Toole, Sharon and Sharp, Linda and Flannelly, Grainne and O'Leary, John J. and Martin, Cara M., Performance of the HPV E6/E7 mRNA Aptima HPV assay combined with partial genotyping compared with the HPV DNA Cobas 4800 HPV test for use in primary screening: Results from the CERVIVA HPV primary screening study in Ireland, International Journal of Cancer, 154, (1), 2024, p53 â€" 64Journal Article, 2024, DOI , URL
• O'Toole, Sharon and Tzortzatou, Olga and Casati, Sara and Beirne, James P. and Savona-Ventura, Charles and Azzopardi, Miriam J. and Micallef, Rita and Calleja-Agius, Jean and Ellul, Bridget, Biobanking rare gynaecological tumours â€" How harmonised is data collection?, European Journal of Surgical Oncology, 51, (4), 2025Journal Article, 2025, DOI , URL
• Azzopardi, Miriam J. and Calleja-Agius, Jean and Calleja, Neville and Galea, Darren and Ellul, Bridget and Micallef, Rita and O'Toole, Sharon A. and Savona-Ventura, Charles, Rare gynaecological cancers in Malta â€" An analysis of incidence between 2010 and 2021, European Journal of Surgical Oncology, 51, (4), 2025Journal Article, 2025, DOI , URL
• Sehouli, Jalid and Boer, Jolijn and Brand, Alison H. and Oza, Amit M. and O†Donnell, Jennifer and Bennett, Katherine and Glaspool, Ros and Lee, Chee Khoon and Ethier, Josee-Lyne and Harter, Philipp and Seebacher-Shariat, Veronika and Chang, Ting-Chang and Cohen, Paul A. and van Gorp, Toon and Chavez-Blanco, Adriana and Welch, Stephen and Hranovska, Hanna and O'Toole, Sharon and Lok, Christianne A.R. and Madariaga, Ainhoa and Rauh-Hain, Jose Alejandro and Fidalgo, Alejandro Perez and Tan, David and Michels, Judith and Pothuri, Bhavana and Fujiwara, Noriko and Rosengarten, Ora and Nishio, Hiroshi and Kim, Se Ik and Mukopadhyay, Asima and Piovano, Elisa and Cecere, Sabrina Chiara and Kohn, Elise C. and Mukherjee, Uma and Nasser, Sara and Lindemann, Kristina and Croke, Jennifer and Chen, Xiaojun and Geissler, Franziska and Bookman, Michael A., How to optimize and evaluate diversity in gynecologic cancer clinical trials: statements from the GCIG Barcelona Meeting, International Journal of Gynecological Cancer, 34, (11), 2024, p1677 â€" 1684Journal Article, 2024, DOI , URL
• Mark P. Ward, F. Park Lewis, C. O"Gorman, Thomas J. Kelly, S. Hurley, Brian E. Henderson, Feras Abu Saadeh, Karen A. Cadoo, John O"Leary, Sharon O"Toole, Prognostic Significance of Circulating Tumour Cells and Disseminating Circulating Tumour Cell Clusters in Epithelial Ovarian Cancer, The Journal of Liquid Biopsy, 1, 2023, p100062 - 100062, p100062-100062Journal Article, 2023, DOI
• Christine White, Stephen Reynolds, Katherine Murphy, Helen Keegan, Padma Naik, Roisin O'Brien, Loretto Pilkington, Imogen Sharkey Ochoa, Grainne Glesson, Nóirín Russell, David S. Nuttall, Prerna Tewari, Fiona Wright, Sharon O"Toole, Linda Sharp, Grainne Flannelly, John O"Leary, Cara Martin, Performance of the HPV E6/E7 mRNA Aptima HPV assay combined with partial genotyping compared with the HPV DNA Cobas 4800 HPV test for use in primary screening: Results from the CERVIVA HPV primary screening study in Ireland, International Journal of Cancer, 154, (1), 2023, p53 - 64, p53-64Journal Article, 2023, DOI
• Adele E. Connor, Claire Hughes, Lea Schäfer, Lorraine L McNally, Deirdre O" Raw, Katayoun Bahramian, Bridget Carr, Ingrid Halligan Dunne, Joanne Lysaght, Sharon O"Toole, Jeremy C. Simpson, Antoinette S. Perry, Involving patients in healthcare research is well documented but can it work in lab-based research?, Research Involvement and Engagement, 9, (1), 2023Journal Article, 2023, DOI
• Karen Mulligan, Sonja Egan, Donal J. Brennan, Irish Society of Gynaecological oncology Public and patient involvement group members, Yvonne O"meara, Sharon O"Toole, Doctor-Patient Communication in an Outpatient Setting, PubMed, 112, (5), 2019, p934 - 934, p934-934Journal Article, 2019
• Duk Ye, Elizabeth R. Smith, Sharon O"Toole, John O"Leary, Bryan T. Hennessy, Xiang"Xi Xu, A potential natural inhibitor in the autocrine regulation among ovarian stromal cell population & its translational implications, Annals of Oncology, 27, 2016, pvi12 - vi12, pvi12-vi12Journal Article, 2016, DOI
• Karolina Weiner"Gorzel, Ma"gorzata Milewska, Danniel Sharpe, Caitlin Beggan, Nazia Faheem, Aloysius McGoldrick, Valerie Toh, Patricia Fitzpatrick, Sharon O"Toole, John O"Leary, Stephen F. Madden, Madeline Murphy, Elaine W. Kay, Malcolm R. Kell, Amanda McCann, Fiona Furlong, Abstract A34: MiR-433 induces cellular senescence rendering ovarian cancer cells less likely to undergo chemotherapy-induced apoptosis, Clinical Cancer Research, 21, (4_Supplement), 2015, pA34 - A34, pA34-A34Journal Article, 2015, DOI
• Cathy Spillane, Niamh Cooke, Karl Egan, Sharon O"Toole, Stephen P. Finn, Dermot Kenny, Orla Sheils, John O"Leary, Abstract 4951: Platelet cloaking of CTCs is a universal phenomenon, which drives metastasis, Cancer Research, 74, (19_Supplement), 2014, p4951 - 4951, p4951-4951Journal Article, 2014, DOI
• Aoife A. Cooke, Britta Stordal, Sharon O"Toole, Orla Shiels, Michael Gallagher, John O"Leary, Brendan Ffrench, Abstract 3382: A systematic approach to the study of cancer stem cells applied to ovarian cancer, Cancer Research, 72, (8_Supplement), 2012, p3382 - 3382, p3382-3382Journal Article, 2012, DOI
• Fiona Furlong, Sine Phelan, Alo McGoldrick, Aoife Maguire, Patricia Fitzpatrick, Sharon O"Toole, Orla Shiels, John O"Leary, Amanda McCann, Abstract LB-338: Stabilisation of MAD2 expression through inhibition of miR-433; A novel mechanism for restoring chemo-responsiveness in ovarian tumours, Cancer Research, 71, (8_Supplement), 2011, pLB - 338, pLB-338Journal Article, 2011, DOI
• Faye Lewis, Mark P. Ward, Feras Abu Saadeh, John O"Leary, Sharon O"Toole, Reply to: In Reference to "A Pilot Study Evaluating the Feasibility of Enriching and Detecting Circulating Tumour Cells from Peripheral and Ovarian Veins in Rare Epithelial Ovarian Carcinomas", European Journal of Surgical Oncology, 2025, p110206 - 110206, p110206-110206Journal Article, 2025, DOI
• Faye Lewis, Mark P. Ward, Feras Abu Saadeh, Catherine O"Gorman, Patrick Maguire, James Beirne, Waseem Kamran, Elzahra Ibrahim, Rebecca Hunter, Sinéad Hurley, Lucy Norris, Brian E. Henderson, Irene Narinda, Marika Kanjuga, Lorraine O"Driscoll, Kathy Gately, Volga M. Saini, Karen A. Cadoo, Cara Martin, John O"Leary, Sharon O"Toole, Abstract B041: Circulating tumor cells are associated with a shorter disease-free interval in patients with advanced high-grade serous carcinoma undergoing neoadjuvant chemotherapy followed by interval cytoreductive surgery, 85, (18_Supplement), 2025, ppB041 - B041, ppB041-B041Published Abstract, 2025, DOI
• Ciara SMc Nevin, Faye Lewis, C Gorman, Feras Abu Saadeh, John O"Leary, Lucy Norris, Mark P. Ward, Patrick Maguire, Scheryll Alken, Sinéad Hurley, Vicky Donachie, Sharon O"Toole, Karen A. Cadoo, 946 Clinical and histopathologic analysis of young onset ovarian cancer: a tertiary referral centre experience over 18 years, ESMO, 2024, ppA380.2 - A381, ppA380.2-A381Published Abstract, 2024, DOI
• Faye Lewis, Mark P. Ward, Catherine O"Gorman, Brian E. Henderson, Sinéad Hurley, James Beirne, Lorraine O"Driscoll, Ciara S. McNevin, Tanya Kelly, Kathy Gately, Ezgi Öner, Volga M Saini, Lucy Norris, Marika Kanjuga, Cara Martin, Patrick Maguire, Karen A. Cadoo, G. M. McManus, John O"Leary, Sharon O"Toole, 1342 Longitudinal detection of circulating tumour cells in serous and non-serous epithelial ovarian carcinomas, 2024, pA425.1 - A425, pA425.1-A425Conference Paper, 2024, DOI
• Bashir M. Mohamed, Mark P. Ward, Mark Bates, Cathy Spillane, Tanya Kelly, Cara Martin, Michael Gallagher, John Kennedy, Fears Abu Saadeh, Noreen Gleeson, Doug A. Brooks, Robert D. Brooks, Stavros Selemidis, Sean Hannify, Eric P. Dixon, Sharon O"Toole, John O"Leary, 599 Circulating tumour cells in breast and ovarian cancer: size-based isolation and ex vivo expansion, Translational research, 2020, pA132.1 - A132, pA132.1-A132Conference Paper, 2020, DOI
• Ward MP, Lewis F, O'Gorman C, Norris LA, Lochrin SE, Kane LE, Kelly TE, Mohamed BM, Ramesh A, O'Connor R, Kilgour E, Henderson B, Kanjuga M, Hurley S, Edgerton L, Tewari P, Gately K, O'Driscoll L, Hokamp K, Cashman S, McManus G, Brooks DA, Selemidis S, Coleman N, Kennedy J, Kamran W, Beirne JP, Maguire P, Abu Saadeh F, Cadoo K, Martin CM, O'Leary JJ, O'Toole SA., Circulating tumour cells are a prognostic indicator in advanced high-grade serous ovarian cancer and are associated with platelets and immune cells following dissemination., British journal of cancer, 2025Journal Article, 2025, DOI
• Wiktoria Irena Batog, Patrick Maguire, Sharon O"Toole, Lucy Norris, Feras Abu Saadeh, 2022-RA-1590-ESGO Identification of groin node metastasis in squamous vulval cancer using preoperative [¹⁸F] FDG-PET/CT. Can unnecessary lymphadenectomy be prevented?, 2022, pA449.2 - A450, pA449.2-A450Conference Paper, 2022, DOI
• Elsayed M. E. Ibrahim, Lucy Norris, Feras Abu Saadeh, Sharon O"Toole, 505 Lymph node status as a predictor of venous thromboembolic risk postoperatively in gynae-oncology, 2021, pA180.1 - A180, pA180.1-A180Conference Paper, 2021, DOI
• Bashir M. Mohamed, Sharon O"Toole, Salah Elbaruni, Lucy Norris, Feras Abu Saadeh, Steven G. Gray, John O"Leary, EP927 Ex-vivo antitumor efficacy of PEGylated-targeted nanodiamonds for docetaxel delivery in ovarian cancer, 2019, pA497.1 - A497, pA497.1-A497Conference Paper, 2019, DOI
• Lea Schäfer, Romina Silva, Gavin Stewart, Sharon O"Toole, Antoinette S. Perry, Abstract A047: Investigating NKAPL, a potential marker for platinum resistance, in high-grade serous ovarian cancer, 85, (18_Supplement), 2025, ppA047 - A047, ppA047-A047Published Abstract, 2025, DOI
• Kate McKendry, Sharon O"Toole, 197 Can D-dimers and fibrinogen aid in the diagnosis of ovarian cancer?, Ovarian cancer, 2020, pA57.1 - A57, pA57.1-A57Conference Paper, 2020, DOI
• Kate McKendry, Sharon O"Toole, 197 Can D-dimers and fibrinogen aid in the diagnosis of ovarian cancer?, Ovarian cancer, 2020, pA57.1 - A57, pA57.1-A57Conference Paper, 2020, DOI
• Karen Mulligan, Sonja Egan, Donal J. Brennan, Yvonne O"meara, Sharon O"Toole, EP1356 Evaluation of doctor-patient communication in a gynaecological oncology outpatient setting, 2019Conference Paper, 2019, DOI
• Karen Mulligan, Sonja Egan, Donal J. Brennan, Yvonne O"meara, Sharon O"Toole, EP1356 Evaluation of doctor-patient communication in a gynaecological oncology outpatient setting, 2019Conference Paper, 2019, DOI
• Ciara S. McNevin, Kathleen R. Murphy, Rachel Dillion, Pierre Murchan, Aisling Hennessy, Órla Fitzpatrick, Megan O"Shaughnessy, Sharon O"Toole, Georgia Thordi, Paul Smyth, Cathal Ó"Brien, Emer Atkinson, Anne"Marie Baird, Steven G. Gray, Brendan Doyle, Niamh Coleman, Stephen P. Finn, Roshni Deepa Deepa kalachand, Karen A. Cadoo, Prevalence Of BRCA1/2 In An Ovarian Cancer Cohort: Outcomes From A Nationwide Testing Program, International Journal of Gynecological Cancer, 35, (2), 2025, p101151 - 101151, p101151-101151Journal Article, 2025, DOI
• Ciara S. McNevin, Rachel Dillion, Simon J. Hollingsworth, Faye Lewis, Sinéad Hurley, Lucy Norris, Mark P. Ward, Vicky Donachie, Patrick Maguire, Scheryll Alken, Niamh Coleman, Waseem Kamran, Feras Abu Saadeh, Catherine O"Gorman, Deborah Donnell, Tom D"Arcy, John O"Leary, Stephen P. Finn, Sharon O"Toole, Karen A. Cadoo, Genetics And Survival Outcomes In Young-Onset Ovarian Cancer: Insights From An 18-Year Tertiary Referral Center Study, 35, (2), 2025, pp100350 - 100350, pp100350-100350Published Abstract, 2025, DOI
• Mark P. Ward, Tanya Kelly, Faye Lewis, Catherine O"Gorman, Brian E. Henderson, Sinéad Hurley, Marika Kanjuga, Emer Atkinson, Cathal Ó"Brien, Patrick Maguire, Waseem Kamran, James Beirne, Niamh Coleman, Karen A. Cadoo, Feras Abu Saadeh, Lucy Norris, Cara Martin, John O"Leary, Sharon O"Toole, EV021/#894" Mutational analysis of circulating tumour DNA (ctDNA) in high grade serous ovarian cancer (HGSC) using cancer personalised profiling by deep sequencing (CAPP-seq), 2024, pA94 - A94, pA94-A94Journal Article, 2024, DOI
• Sharon O"Toole, Dearbhla Bayle, Mary Biggs, Bridget Carr, Bernie Carter, Joseph R. Casey, Avonne E. Connor, Catherine Conway, K. Costello, H. Randall Craig, Jacqueline S. Daly, Kellie Dean, Orla Dolan, John Feeney, M. Fenton, Mary Fitzquigley, H. Forristal, Louis Fox, Fiona Furlong, Elaine Gill, Helen Greally, K.M. Hogan, Roberta Horgan, Lindsay Houlihan, Claire Hughes, Robin Ireland, Gail V. Irvine, Lucy Jessop, Asia Jordan, Marika Kanjuga, Úna Kennedy, Bridget Kerrigan, Palak Kundu, Faye Lewis, John Loughrey, Áine Lyng, Cara Martin, Aideen McCabe, M. K. McLaren, A. McNamara, Yvonne Morrissey, Jessica Mulcahy, Anne E. Murphy, Kathryn Murphy, Lucy Eldersveld Murphy, Catherine O"Gorman, Catherine O"Leary, Yvonne O"meara, Eve O"Toole, Ken Rogan, Lea Schäfer, Karina Toolan, Catherine Walsh, L. O'Connell, Frances J. Drummond, EV359/#1028" Ovarian cancer symptom awareness levels remain static in Ireland over a 3-year period; a concerted national approach is warranted, 2024, pA271.1 - A271, pA271.1-A271Journal Article, 2024, DOI
• Faye Lewis, Mark P. Ward, Catherine O"Gorman, Brian E. Henderson, Sinéad Hurley, James Beirne, Lorraine O"Driscoll, Kathy Gately, Ezgi Öner, Volga M Saini, Marika Kanjuga, Lucy Norris, Cara Martin, Tanya Kelly, Patrick Maguire, Feras Abu Saadeh, Waseem Kamran, Karen A. Cadoo, Niamh Haughey, G. M. McManus, John O"Leary, Sharon O"Toole, EV290/#1177" Radiological size of the pelvic mass in high-grade serous carcinomas inversely correlates with circulating tumour cell detection from the ovarian vein at surgery, 2024, pA233.3 - A234, pA233.3-A234Journal Article, 2024, DOI
• Brian E. Henderson, Niamh E. Buckley, James Beirne, Lorraine O"Driscoll, Lucy Norris, Faye Lewis, Marika Kanjuga, Paul B. Mullan, Sinéad Hurley, Kathy Gately, John O"Leary, Sharon O"Toole, EV266/#1022" CLuB: the all-Ireland cancer liquid biopsies consortium, 2024, pA221.2 - A221, pA221.2-A221Journal Article, 2024, DOI
• Kate McKendry, Stephen Duff, Yanmei Huang, Mostafa Redha, ine Scanlon, Feras Abu Saadeh, Noreen Gleeson, John O Leary, Lucy Norris, Sharon O"Toole, A novel biomarker panel of HE4 and D-dimer improves ovarian cancer diagnosis in postmenopausal women presenting with symptomatic pelvic masses: a prospective cohort study, 2020Journal Article, 2020, DOI
• Abdul L. Shakerdi, Eileen M. Finnegan, Yonghua Sheng, Karina Vidovic, Jessica M. Logan, Mark P. Ward, Sharon O"Toole, Cara Martin, Stavros Selemidis, Doug A. Brooks, John O"Leary, Prerna Tewari, Crosstalk Between Inflammasome Signalling and Epithelial-Mesenchymal Transition in Cancer and Benign Disease: Mechanistic Insights, Context-Dependence, and Therapeutic Opportunities, Cells, 14, (20), 2025, p1594 - 1594, p1594-1594Review Article, 2025, DOI
• Abdul L. Shakerdi, Eileen M. Finnegan, Yonghua Sheng, Karina Vidovic, Jessica M. Logan, Mark P. Ward, Sharon O"Toole, Cara Martin, Stavros Selemidis, Doug A. Brooks, John O"Leary, Prerna Tewari, Crosstalk Between Inflammasome Signalling and Epithelial-Mesenchymal Transition in Cancer and Benign Disease: Mechanistic Insights, Context-Dependence, and Therapeutic Opportunities, Cells, 14, (20), 2025, p1594 - 1594, p1594-1594Review Article, 2025, DOI
• Lea Schäfer, Romina Silva, Gavin Stewart, Sharon O"Toole, Antoinette S. Perry, EV019/#412" Investigating NKAPL, a potential marker for platinum resistance, in high-grade serous ovarian cancer, 2024, pA92.3 - A93, pA92.3-A93Journal Article, 2024, DOI
• Lea Schäfer, Romina Silva, Gavin Stewart, Sharon O"Toole, Antoinette S. Perry, EV019/#412" Investigating NKAPL, a potential marker for platinum resistance, in high-grade serous ovarian cancer, 2024, pA92.3 - A93, pA92.3-A93Journal Article, 2024, DOI
• Jessica Eakins, Laura O"conner, Julie David, Mark C. Bates, Ola Ibrahim, Cara Martin, Hassan Rajab, Steven G. Gray, Feras Abu Saadeh, Stavros Selemidis, DA Brook, Sharon O"Toole, Derek G. Doherty, John O"Leary, Bashir M. Mohamed, EV270/#1221" Ex vivo upregulation of CD1d expression to enhance the therapeutic benefit of iNKT cells of ovarian cancer, 2024, pA224.1 - A224, pA224.1-A224Journal Article, 2024, DOI
• Jessica Eakins, Laura O"conner, Julie David, Mark C. Bates, Ola Ibrahim, Cara Martin, Hassan Rajab, Steven G. Gray, Feras Abu Saadeh, Stavros Selemidis, DA Brook, Sharon O"Toole, Derek G. Doherty, John O"Leary, Bashir M. Mohamed, EV270/#1221" Ex vivo upregulation of CD1d expression to enhance the therapeutic benefit of iNKT cells of ovarian cancer, 2024, pA224.1 - A224, pA224.1-A224Journal Article, 2024, DOI
• Stephen Reynolds, Ola Ibrahim, Ellen O"reilly, Eleanora Rivellini, Christine White, Padma Naik, Helen Keegan, Nóirín Russell, Prerna Tewari, Sharon O"Toole, John O"Leary, Cara Martin, EV399/#1204" Triage of HPV positive primary screening patients using methylation biomarkers, 2024, pA295 - A295, pA295-A295Journal Article, 2024, DOI
• Stephen Reynolds, Ola Ibrahim, Ellen O"reilly, Eleanora Rivellini, Christine White, Padma Naik, Helen Keegan, Nóirín Russell, Prerna Tewari, Sharon O"Toole, John O"Leary, Cara Martin, EV399/#1204" Triage of HPV positive primary screening patients using methylation biomarkers, 2024, pA295 - A295, pA295-A295Journal Article, 2024, DOI
• Martin CM, Astbury K, Kehoe L, O'Crowley JB, O'Toole S, O'Leary JJ., The use of MYBL2 as a novel candidate biomarker of cervical cancer., Methods in molecular biology (Clifton, N.J.), 1249, 2015, p241-251Journal Article, 2015
• SA O'Toole, A Laios, BL Sheppard, NC Gleeson, T D'Arcy, EPJ McGuinness, J Bonnar, O Sheils and JJ O'Leary. , Potential predictors of chemotherapy response in ovarian cancer how do we define chemosensitivity?, Laboratory Investigation, United States and Canadian Society of Pathology, Atlanta, USA, Feb 2006, 86, (Suppl 1), Nature, 2006, pp190AMeeting Abstract, 2006
• Laios A, O'Toole SA, Sheppard BL, Gleeson NC, D'Arcy T, McGuinness EPJ, Ring M, Sheils O and O'Leary JJ. , Molecular profiling of primary versus recurrent ovarian serous papillary adenocarcinomas. , Laboratory Investigation, United States and Canadian Society of Pathology, Atlanta, USA, Feb 2006, 86, (Suppl 1), Nature, 2006, pp185 - 185Meeting Abstract, 2006
• O'Toole SA, Sheppard BL, McGuinness EP, Gleeson NC, Yoneda M, Bonnar J, The MTS assay as an indicator of chemosensitivity/resistance in malignant gynaecological tumours. , Cancer Detection and Prevention , 27, (1), 2003, p47 - 54Journal Article, 2003, DOI , URL
• O'Toole SA, Sheppard BL, McGuinness E, Gleeson NC, Bonnar J., Serous papillary adenocarcinomas of the ovary display heterogeneity in their response to chemotherapy., International Journal of Gynaecological Cancer, 11, (5), 2001, p365 - 371Journal Article, 2001, DOI , URL
• O'Toole S, McGuinness E, Sheppard B, Bonnar J., Plasminogen activators and inhibitors in ovarian adenocarcinomas., International Journal of Gynaecological Cancer , 9, 1999, p61 - 66Journal Article, 1999, URL
• O'Toole SA, Dunn E, Sheppard BL, Klocker H, Bektic J, Smyth P, Martin C, Sheils O, O'Leary JJ, Genome-wide analysis of deoxyribonucleic acid in endometrial cancer using comparative genomic hybridization microarrays, International Journal of Gynecological Cancer , 16, (2), 2006, p834 - 842Journal Article, 2006, DOI
• O'Toole SA, Sheppard BL, Laios A, O'Leary JJ, McGuinness EP, D'Arcy T, Bonnar J., Potential predictors of chemotherapy response in ovarian cancer--how do we define chemosensitivity?, Gynecological Oncology, 104, (2), 2007, p345 - 351Journal Article, 2007, URL
• Laios, A., O'Toole, S., Flavin, R., Martin, C., Kelly, L., Ring, M., Finn, S.P., (...), O'Leary, J. , Potential role of miR-9 and miR-223 in recurrent ovarian cancer , Molecular Cancer, 7, 2008, part. no. 35Journal Article, 2008, DOI , TARA - Full Text
• Laios, A., O'Toole, S.A., Flavin, R., Martin, C., Ring, M., Gleeson, N., D'Arcy, T., (...), O' Leary, J.J. , An integrative model for recurrence in ovarian cancer , Molecular Cancer, 7, 2008Journal Article, 2008, DOI
• Gallagher MF, Flavin RJ, Elbaruni SA, McInerney JK, Smyth PC, Salley YM, Vencken SF, O'Toole SA, Laios A, Lee MY, Denning K, Li J, Aherne ST, Lao KQ, Martin CM, Sheils OM, O'Leary JJ, Regulation of microRNA biosynthesis and expression in 2102Ep embryonal carcinoma stem cells is mirrored in ovarian serous adenocarcinoma patients., Journal of ovarian research, 2, 2009, p19Journal Article, 2009, DOI , URL , TARA - Full Text
• Flavin RJ, Smyth PC, Finn SP, Laios A, O'Toole SA, Barrett C, Ring M, Denning KM, Li J, Aherne ST, Aziz NA, Alhadi A, Sheppard BL, Loda M, Martin C, Sheils OM, O'Leary JJ, Altered eIF6 and Dicer expression is associated with clinicopathological features in ovarian serous carcinoma patients., Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 21, (6), 2008, p676-84Journal Article, 2008, DOI
• Egan K, Crowley D, Smyth P, O'Toole S, Spillane C, Martin C, Gallagher M, Canney A, Norris L, Conlon N, McEvoy L, Ffrench B, Stordal B, Keegan H, Finn S, McEneaney V, Laios A, Ducrée J, Dunne E, Smith L, Berndt M, Sheils O, Kenny D, O'Leary J, Platelet Adhesion and Degranulation Induce Pro-Survival and Pro-Angiogenic Signalling in Ovarian Cancer Cells, PLoS ONE, 6, (10, e26125), 2011Journal Article, 2011, DOI , URL , TARA - Full Text
• Murphy MA, O'Connell DJ, O'Kane SL, O'Brien JK, O'Toole S, Martin C, Sheils O, O'Leary JJ, Cahill DJ, Epitope presentation is an important determinant of the utility of antigens identified from protein arrays in the development of autoantibody diagnostic assays, Journal of Proteomics, 75, (15), 2012, p4668 - 4675Journal Article, 2012, DOI , URL , TARA - Full Text
• Gallagher MF, Heffron CC, Laios A, O'Toole SA, Ffrench B, Smyth PC, Flavin RJ, Elbaruni SA, Spillane CD, Martin CM, Shelis OM, O'Leary JJ. , Suppression of Cancer Stemness p21-regulating mRNA and microRNA Signatures in Recurrent Ovarian Cancer Patient Samples. , Journal of Ovarian Research, 5, (1), 2012, p2-Journal Article, 2012, DOI
• Ovarian Cancer Chemoresistance in, editor(s)Dr. rer. nat. Manfred Schwab , Encyclopedia of Cancer, SpringerReference, 2010, [O'Toole SA, O'Leary JJ]Book Chapter, 2010, DOI , URL
• Gene expression profiling in cervical cancer: identification of novel markers for disease diagnosis and therapy in, Methods Mol Biol, 2009, pp333 - 359, [Martin CM, Astbury K, McEvoy L, O'Toole S, Sheils O, O'Leary JJ]Book Chapter, 2009, DOI
• Laios A, Mohamed BM, Kelly L, Flavin R, Finn S, McEvoy L, Gallagher M, Martin C, Sheils O, Ring M, Davies A, Lawson M, Gleeson N, D'Arcy T, d'Adhemar C, Norris L, Langhe R, Saadeh FA, O'Leary JJ, O'Toole SA, Pre-Treatment of Platinum Resistant Ovarian Cancer Cells with an MMP-9/MMP-2 Inhibitor Prior to Cisplatin Enhances Cytotoxicity as Determined by High Content Screening., International journal of molecular sciences, 14, (1), 2013, p2085-103Journal Article, 2013, DOI , TARA - Full Text
• Pilkington L, Keegan H, O'Toole S, Singh S, Cleary S, Prendiville W, Darcy T, Turner MJ,, Von Bunau G, Anglim M, O'Leary JJ, Martin CM. , The utility of HPV testing in predicting disease recurrence post colposcopic treatment for cervical intraepithelial neoplasia. , Modern Pathology/Laboratory Investigations, United Stated and Canadian Academy of Pathology, San Antonio, Texas, February 26-March 4, 91, (Supplement 1S), 2011, pp263A-Meeting Abstract, 2011
• Abu Saadeh F, Norris L, O'Toole S, Gleeson N, Venous thromboembolism in ovarian cancer: Incidence, risk factors and impact on survival., European Journal of Obstetrics & Gynecology and Reproductive Biology , 170, (1), 2013, p214 - 218Journal Article, 2013
• Abu Saadeh F, O'Toole S, Gleeson N, Norris L, Peak ant-Xa levels following LMWH (tinzaparin) prophylaxis in gynaecological cancer patients post surgery, Thrombosis Research, 7th Internation Conference on Thrombosis & Hemostatis Issues in Cancer, , Bergamot Italy, May 2014, edited by A Falanga, B. Brenner, F, Rickles , 133, (Suppl 2), Elsevier, 2014Published Abstract, 2014
• Abu Saadeh. F, Norris. L, O' Toole. S, Langhe. R, Gleeson. N., ETP as a marker for venous thromboembolism in gynaecologial cancer patients post surgery, International Journal of Gynecological Cancer, 14th Biennial Meeting of the International Gynecological Cancer Society., Vancouver, Canada, October 2012, 22, (Suppl 3), 2012, ppE249-Published Abstract, 2012
• Abu Saadeh. F, Norris. L, O' Toole, Gleeson. N., Assessing the risk and mortality of venous thromboembolism in ovarian cancer., International Journal of Gynecological Cancer, 14th Biennial Meeting of the International Gynecological Cancer Society., Vancouver, Canada, October 2012, 22, (Suppl 3), 2012, ppE246-Meeting Abstract, 2012
• White C, Keegan H, Pilkington L, Ruttle C, Kerr P, Sharp L, O'Toole S, Turner M, Prendiville W, D'Arcy T, Fitzpatrick M, Lenehan P, Flannelly G, O'Leary JJ, Martin CM, Evaluation of the clinical performance of the cobas 4800 HPV test in patients referred for colposcopy., Journal of clinical microbiology, 51, (10), 2013, p3415-7Journal Article, 2013, DOI , TARA - Full Text

• O'Toole S, Sheppard B.L., Bonnar J, McGuinness E, Gleeson N, Cell Culture drug sensitivity/resistance testing of malignant gynaecological tumours. , British Journal of Obstetrics and Gynaecology , 107, (6), 2000, p818 - 819Journal Article
• O'Leary JJ, White C, Spillane C, Naik, P, O'Brien, R, Reynolds, S, Pham, T, Pilkington, L, Sharkey Ochoa, I, Bolger, N, Barry O'Crowley, J, Tewari, P, O'Toole, S, Sweeney, M, Keegan, H, Normand, C, Sharp, L, Flannelly, G, Martin, CM. , Cervical screening: A new way forward (tests of risk and tests of disease) [version 1; referees: 1 approved, 1 approved with reservations]., HRB Open Research, 1, (3), 2018Journal Article, DOI
• Laios A, O'Toole SA, Sheppard BL, Gleeson NC, D'Arcy T, McGuinness EPJ, Ring M, Sheils O, O'Leary JJ. (ed.), Irish Association for Cancer Research, Galway, Ireland, March 2006, 2006Proceedings of a Conference
• A Laios, SA O'Toole, B Sheppard, N Gleeson, T D'Arcy, E PJ McGuinness, M Ring, O Sheils and JJ O'Leary. , Transcriptome profiling of primary and recurrent ovarian cancers, Junior Obstetrics and Gynaecology Society, Dublin, Nov 2005, 2005Meeting Abstract
• O'Toole S, Laios A, Sheppard B, Smyth P, O'Regan E, Sheils O, O'Leary J. , Expression profiling of endometrial stromal cells treated with estradiol and phytoestrogens. , 20th European Congress of Pathology, Paris, Sept 2005, 2005Meeting Abstract
• O'Toole SA, Laios A, Sheppard BL, Gleeson NC, D'Arcy T, Mc Guinness EPJ, Bonnar J, Sheils O, O'Leary JJ. , Angiogenesis markers in ovarian cancer act as prognostic markers but not indicators of chemotherapy response, Pathological Society of Great Britain and Ireland, Newcastle, UK, July 2005, 2005Meeting Abstract
• O'Toole SA, Laios A, Sheppard BL, Gleeson NC, D'Arcy T, Mc Guinness EPJ, Bonnar J, Sheils O, O'Leary JJ. , Potential Predictors of Chemotherapy Response in Ovarian Cancer., Irish gynaecological oncology society, Belfast, 2005, 2005Meeting Abstract
• O'Toole SA, Sheppard BL, D'Arcy T, Mc Guinness EPJ, Gleeson NC, Bonnar J, Sheils O, O'Leary JJ. , Angiogenesis in Ovarian Cancer does not predict response to chemotherapy., Irish Association for Cancer Research, Kilkenny, Ireland, March 2005, 2005Meeting Abstract
• O'Toole SA, Sheppard BL, D'Arcy T, Mc Guinness EPJ, Gleeson NC, Bonnar J, Sheils O, O'Leary JJ. , Multidrug resistance gene only plays a role in some ovarian cancers, Irish Association for Cancer Research, Kilkenny, Ireland, March 2005, 2005Meeting Abstract
• O'Toole SA, Dunn E, Sheppard BL, Klocker H, Bektic J, Smyth P, Martin C, Sheils O, O'Leary JJ. , Genome wide analysis of DNA in endometrial cancer using comparative genomic hybridisation microarrays, Irish gynaecological oncology society,, Cork, Ireland, 2004Meeting Abstract
• SA O'Toole, E Dunn, BL Sheppard, O Sheils, JJ O' Leary, W Wuttke, D. Seidlova-Wuttke. , Oestrogen regulated gene expression in normal and malignant endometrial tissue. , Irish gynaecological oncology society, Cork, Ireland, 2004Meeting Abstract
• SA O'Toole, E Dunn, BL Sheppard, O Sheils, JJ O' Leary, W Wuttke, D. Seidlova-Wuttke. , Oestrogen regulated gene expression in normal and malignant endometrial tissue. , 5th International Symposium on Women's Health and Menopause, Florence, Italy, Apr 2004, 2004Meeting Abstract
• SA O'Toole, BL Sheppard, P Smyth, C Martin, O Sheils, JJ O'Leary, B Spengler, V Christoffel, Genome wide analysis of DNA in endometrial cells treated with phytoestrogens using comparative genomic hybridisation microarrays, 5th International Symposium on Women's Health and Menopause, Florence, Italy, Apr 2004, 2004Meeting Abstract
• SA O'Toole, E Dunn, BL Sheppard, P Smyth, C Martin, O Sheils, JJ O'Leary, J. Bektic, H. Klocker. , Genome wide analysis of DNA in endometrial cancer using comparative genomic hybridisation microarrays. , 5th International Symposium on Women's Health and Menopause, Florence, Italy, Apr 2004, 2004Meeting Abstract
• O'Toole SA, Sheppard BL, Sheils O, Smyth P, Martin C, O'Leary JJ, Spengler B, Christoffel V. , Genome wide analysis of DNA sequence copy number in endometrial cells treated with phytoserms using comparative genomic hybridisation microarrays. , Irish Association for Cancer Research, Kilkenny, Ireland, Apr 2003, 2003Meeting Abstract
• O'Toole S, Sheppard B, Bonnar J, McGuinness E. , Fibrinolysis in Ovarian Carcinomas. , Joint IACR/ISMO Cancer Research Meeting, Belfast, 1999, 1999Meeting Abstract
• O'Toole S, Chemosensitivity Testing of Gynaecological Tumours, 1st International Postgraduate Student Conference., Dublin, 1998, 1998Meeting Abstract
• O'Toole SA, Sheppard BL, McGuinness EPJ, Gleeson NC, Yoneda M, Bonnar J., Determining the response of gynaecological tumours to chemotherapy using an MTS cytotoxicity assay in combination with an explant culture technique, British Journal of Cancer , 86, (Suppl 1), 2002, pS46 - S46Journal Article
• O'Toole S, Sheppard BL, Bonnar J, McGuinness E, Gleeson N, Cell Culture drug sensitivity/resistance testing of malignant gynaecological tumours., Irish Journal of Medical Science, 168, (Suppl 3), 1999, pp35 - 35Meeting Abstract
• Laios A, O'Toole SA, Sheppard BL, Gleeson NC, D'Arcy T, McGuinness EPJ, Ring M, Sheils O, Smyth P, O'Leary JJ., Recurrent ovarian cancer cDNA signatures., Centenary Meeting of the Pathological Society of Great Britain and Ireland , Manchester, July 2006, 2006Meeting Abstract
• CM Martin, K Astbury, R Henfrey, O Sheils, M Gallagher, C Heffron, C Logan, SA O'Toole, JJ O'Leary, miRNA expression signatures in cervical cancer, Journal of RNAi and Gene Silencing, RNAi2006: Advances in RNA Interference Research, St Anne's College, Oxford, United Kingdom, March 2006, 2, (2), 2006Meeting Abstract
• Ibrahim N, Norris L, O'Toole S, McHugh T, Gleeson N, Does extended thromboprophylaxis help reduce the incidence of venous thromboembolism in gynaecological cancer patients?, Thrombosis Research, 7th Internation Conference onal Thrombosis & Hemostatis Issues in Cancer,, Bergamo Italy, May 2014, edited by A Falanga, B. Brenner, F, Rickles , 133, (Suppl 2), Elsevier, 2014Published Abstract

-Early diagnostics in ovarian cancer
-Chemoresistance in ovarian cancer
Chemosensitivity/Resistance testing of malignant gynaecological tumours
-Examination of Fibrinolytic systems of malignant gynaecological tumours
-Examination of angiogenesis in ovarian cancers.
-Examination of multidrug resistance genes in gynaecological tumours.
-Estrogen regulated genes in endometrial cancer.
-PhytoSERMs and Endometrial Cancer

Other health sciences, Cancer, Medical, health and life sciences,

• Member of European Association for Cancer Research. Member of Irish Association for Cancer Research
• -Member of Cancer Trials Ireland
• -Co-ordinator of INNOVATION- the Irish National Network for Ovarian Cancer Collaboration.
• -Executive Committee of the Irish Society of Gynaecological Oncology (ISGO)
• -Member of the European Society for Gynaecological Oncology (ESGO)