Dr. Joanne Ramsey

Dr. Joanne Ramsey

Assistant Professor, Pharmacology & Therapeutics

https://www.tcd.ie/medicine/pharmacology-therapeutic/staff/ramseyj/

Biography

Assistant Professor and course co-ordinator of the Pharmaceutical Medicine Masters/PG Dip course. Highly experienced researcher with a demonstrated history of working in Scientific Research and Healthcare education. Skilled in Cancer Research, Models of Disease, Drug Manufacturing and Delivery, and Translational Pharmaceutics. Experienced in Project Management and liaising with Project Stakeholders. Doctor of Philosophy (PhD) focused in oncology drug development and cancer biology from Queen's University Belfast and Postgraduate Diploma from Royal College of Surgeons in Ireland in Health Professionals Education.

Publications and Further Research Outputs

  • Fernández Fernández E and Santos-Carballal B and de Santi C and Ramsey JM and MacLoughlin R and Cryan SA and Greene CM, Biopolymer-Based Nanoparticles for Cystic Fibrosis Lung Gene Therapy Studies., Materials (Basel, Switzerland), 2018Journal Article, 2018, DOI
  • Tivnan A and Heilinger T and Ramsey JM and O'Connor G and Pokorny JL and Sarkaria JN and Stringer BW and Day BW and Boyd AW and Kim EL and Lode HN and Cryan SA and Prehn JH, Anti-GD2-ch14.18/CHO coated nanoparticles mediate glioblastoma (GBM)-specific delivery of the aromatase inhibitor, Letrozole, reducing proliferation, migration and chemoresistance in patient-derived GBM tumor cells., Oncotarget, 2017Journal Article, 2017, DOI
  • Roulston GD and Burt CL and Kettyle LM and Matchett KB and Keenan HL and Mulgrew NM and Ramsey JM and Dougan C and McKiernan J and Grishagin IV and Mills KI and Thompson A, Low-dose salinomycin induces anti-leukemic responses in AML and MLL., Oncotarget, 2016Journal Article, 2016, DOI
  • Byrne M and Murphy R and Kapetanakis A and Ramsey J and Cryan SA and Heise A, Star-Shaped Polypeptides: Synthesis and Opportunities for Delivery of Therapeutics., Macromolecular rapid communications, 2015Journal Article, 2015, DOI
  • Kelly C and Lawlor C and Burke C and Barlow JW and Ramsey JM and Jefferies C and Cryan SA, High-throughput methods for screening liposome-macrophage cell interaction., Journal of liposome research, 2014Journal Article, 2014, DOI
  • Kelly C and Yadav AB and Lawlor C and Nolan K and O'Dwyer J and Greene CM and McElvaney NG and Sivadas N and Ramsey JM and Cryan SA, Therapeutic aerosol bioengineering of siRNA for the treatment of inflammatory lung disease by TNFα gene silencing in macrophages., Molecular pharmaceutics, 2014Journal Article, 2014, DOI
  • Mulgrew NM and Kettyle LM and Ramsey JM and Cull S and Smyth LJ and Mervyn DM and Bijl JJ and Thompson A, c-Met inhibition in a HOXA9/Meis1 model of CN-AML., Developmental dynamics : an official publication of the American Association of Anatomists, 2014Journal Article, 2014, DOI
  • Ramsey JM and Kettyle LM and Sharpe DJ and Mulgrew NM and Dickson GJ and Bijl JJ and Austin P and Mayotte N and Cellot S and Lappin TR and Zhang SD and Mills KI and Krosl J and Sauvageau G and Thompson A, Entinostat prevents leukemia maintenance in a collaborating oncogene-dependent model of cytogenetically normal acute myeloid leukemia., Stem cells (Dayton, Ohio), 2013Journal Article, 2013, DOI
  • Ramsey JM and Hibbitts A and Barlow J and Kelly C and Sivadas N and Cryan SA, 'Smart' non-viral delivery systems for targeted delivery of RNAi to the lungs., Therapeutic delivery, 2013Journal Article, 2013, DOI
  • Wheadon H and Ramsey JM and Dobbin E and Dickson GJ and Corrigan PM and Freeburn RW and Thompson A, Differential Hox expression in murine embryonic stem cell models of normal and malignant hematopoiesis., Stem cells and development, 2011Journal Article, 2011, DOI
  • Sweeney L and McCloskey AP and Higgins G and Ramsey JM and Cryan SA and MacLoughlin R, Effective nebulization of interferon-γ using a novel vibrating mesh., Respiratory research, 2019Journal Article, 2019, DOI
  • Vencken S and Foged C and Ramsey JM and Sweeney L and Cryan SA and MacLoughlin RJ and Greene CM, Nebulised lipid-polymer hybrid nanoparticles for the delivery of a therapeutic anti-inflammatory microRNA to bronchial epithelial cells., ERJ open research, 2019Journal Article, 2019, DOI
  • McKiernan PJ and Lynch P and Ramsey JM and Cryan SA and Greene CM, Knockdown of Gene Expression in Macrophages by microRNA Mimic-Containing Poly (Lactic-co-glycolic Acid) Microparticles., Medicines (Basel, Switzerland), 2018Journal Article, 2018, DOI
  • Sensitivity of hematopoietic and leukemic stem cells to Hoxa gene levels. in, Stem Cells and Cancer Stem Cells: Therapeutic Applications in Disease and Injury, Springer, 2011, [Lebert-Ghali CE, Ramsey JM, Thompson A, Bijl JJ]Book Chapter, 2011
  • Nanotechnology Approaches to Pulmonary Drug Delivery - Targeted delivery of small molecule and gene-based therapeutics to the lung in, Volume XXV: Site specific drug delivery, targeting and gene therapy, Elsevier Pharmaceutical Nanotechnology Series, 2017, [RachelGaul, Joanne M.Ramsey, Andreas Heise, Sally-Ann Cryan, Catherine M.Greene]Book Chapter, 2017

Research Expertise

Pharmacology & Toxicology including drug formulation and delivery, Genetics and Genomics, Medical, Health and Life Sciences & Technologies, Other Health Sciences, Respiratory Medicine, Other Clinical Medicine, Health Care & Health Services (including Health Technology and Health Information Systems), Oncology and cancer biology,

Recognition

  • International Association for the Study of Lung Cancer Present