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Dr. Laura Mc Cullagh

Dr. Laura Mc Cullagh

Clinical Senior Lecturer, Pharmacology & Therapeutics


Biography

Dr Laura McCullagh is Chief I Pharmacist & Head of Research, National Centre for Pharmacoeconomics (NCPE) and Clinical Senior Lecturer, Pharmacology & Therapeutics. She holds a PhD for her research in Health Technology Assessment (HTA). In the NCPE, she has led over 50 HTA evaluations; these have informed HSE drug reimbursement decision-making. Previous roles have included Associate Professor of HTA & Pharmacoeconomcis, Discipline of Pharmacology & Therapeutics, Trinity College Dublin. She represents Ireland on the European Commission HTA Coordination Group (medicinal products). She publishes research in international, peer-reviewed journals. She is a member of Cochrane. She is on the Editorial Boards of PharmacoEconomics and Frontiers in Medicine. She provides peer-review for heath-economics and clinical journals, for the Medical Research Council, UK and the Veni Scheme, Netherlands Organization for Scientific Research. She is on the ISPOR Europe Research Programme Committee. She is on the Research Ethics Committee, Health Policy and Management-Centre for Global Health, Trinity College Dublin. Dr McCullagh is on the Board of Management and Court of Examiners, MSc Pharmaceutical Medicine, Discipline of Pharmacology & Therapeutics. She supervises post-doctoral, PhD, MD, MSc and undergraduate researchers. She is internal examiner to PhD and MSc candidates. She holds undergraduate and postgraduate teaching commitments. She leads the development and implementation of the HTA Module of the annual National Patient Education Programme (in collaboration with IPPOSI). She is a member of the National Cancer Epi Network. She was a member of the Pan-European Piperska Group (2013-2017). She was a member of the National Prostate Cancer Research Consortium (2014-2015). She was on the Expert Advisory Group for the HTA of a National Screening Programme for Atrial Fibrillation. She was a member of the National Cancer Control Programme Technology Review Committee (2015-2018).

Publications and Further Research Outputs

  • McCullagh L, Adams R, Barry M, Schmitz S, Walsh C, Evaluation Of 'Real-World' Ipilimumab Data In Ireland., Value Health, 18, (7), 2015, ppA441-A441-Poster, 2015
  • Godman B, Malmström RE, Diogene E, Gray A, Jayathissa S, Timoney A, Acurcio F, Alkan A, Brzezinska A, Bucsics A, Campbell SM, Czeczot J, de Bruyn W, Eriksson I, Yusof FA, Finlayson AE, Fürst J, Garuoliene K, Guerra Júnior A, Gulbinovi, J, Are new models needed to optimize the utilization of new medicines to sustain healthcare systems?, 2015Journal Article, 2015, DOI
  • Godman B, Finlayson AE, Cheema PK, Zebedin-Brandl E, Gutiérrez-Ibarluzea I, Jones J, Malmström RE, Asola E, Baumgärtel C, Bennie M, Bishop I, Bucsics A, Campbell S, Diogene E, Ferrario A, Fürst J, Garuoliene K, Gomes M, Harris K, Haycox A, Personalizing health care: feasibility and future implications., 2013Journal Article, 2013
  • Malmström RE, Godman BB, Diogene E, Baumgärtel C, Bennie M, Bishop I, Brzezinska A, Bucsics A, Campbell S, Ferrario A, Finlayson AE, Fürst J, Garuoliene K, Gomes M, Gutiérrez-Ibarluzea I, Haycox A, Hviding K, Herholz H, Hoffmann M, Jan S, Dabigatran - a case history demonstrating the need for comprehensive approaches to optimize the use of new drugs., 2013Journal Article, 2013, DOI
  • McCullagh L, Barry M, Prescribing trends for dabigatran etexilate in primary care., 2012Journal Article, 2012
  • McCullagh L, Tilson L, Walsh C, Barry M, A cost-effectiveness model comparing rivaroxaban and dabigatran etexilate with enoxaparin sodium as thromboprophylaxis after total hip and total knee replacement in the irish healthcare setting., 2009Journal Article, 2009, DOI
  • Schmitz S, McCullagh L, Adams R, Walsh C, Identifying and Revealing the Importance of Decision-Making Criteria for Health Technology Assessment: A Retrospective Analysis of Reimbursement Recommendations in Ireland, PharmacoEconomics, 2016Journal Article, 2016, DOI
  • McCullagh L, Barry M, The Pharmacoeconomic Evaluation Process in Ireland, PharmacoEconomics, 34, (12), 2016, p1267 - 1276Journal Article, 2016, DOI
  • Morgan RB, McCullagh L, Barry M, Daly C, The cost of inpatient management of heart failure patients: a microcosting study in the Irish healthcare setting., 2016Journal Article, 2016
  • Ermisch M, Bucsics A, Vella Bonanno P, Arickx F, Bybau A, Bochenek T, van de Casteele M, Diogene E, Fürst J, Garuolien" K, van der Graaff M, Gulbinovi" J, Haycox A, Jones J, Joppi R, Laius O, Langner I, Martin AP, Markovic-Pekovic V, McCullagh L, Payers' Views of the Changes Arising through the Possible Adoption of Adaptive Pathways., 2016Journal Article, 2016, DOI
  • McCullagh LM, Tilson L, Adams R, Barry M, HTA Informed Price Negotiations: Cost Savings To The Health Payer in Ireland., 2014Journal Article, 2014
  • McCullagh L, Barry M., Survival analysis used in company submissions to the National Centre for Pharmacoeconomics, Value Health, 16, (7), 2013, ppA398 - A398Poster, 2013
  • Schmitz S, McCullagh L, Adams R, Barry M, Walsh C, A retrospective analysis of drug reimbursement decisions in Ireland. A multi criteria decision analysis approach., Value Health, 2013, 16, (7), 2013, ppA465 - A465Poster, 2013
  • Adams R, Gray E, McCullagh L, Schmitz S, Barry M, Walsh C, Budget impact and thresholds: how are real decisions made? Expected utility or Prospect Theory, Value Health, 16, (7), 2013, ppA490 - A490Poster, 2013
  • McCullagh L, Walsh C, Barry M, Integration of value of information into the decision making process in Ireland, Value Health, 15, (7), 2012, ppA317 - A317Poster, 2012
  • McCullagh L, Usher C, Barry M, A review of the primary care prescribing of dabigatran etexilate and rivaroxaban in Ireland, Value Health, 14, (7), 2011, ppA390 - A390Poster, 2011
  • McCullagh L, Walsh C, Barry M, Prioritizing further research using the expected value of perfect information: application to VTE prophylaxis post total hip replacement, Value Health, 13, (7), 2010, ppA359 - A359Poster, 2010
  • McCullagh L, Tilson L, Walsh C, Barry M, Cost effectiveness of rivaroxaban and dabigatran etexilate for the prophylaxis of venous thromboembolism and associated long term compliactions post total hip replacement in Ireland, Value Health, 12, (7), 2009, ppA334 - A334Poster, 2009
  • Spillane S, McCullagh L, Barry M, Usher C, Analysis of Pharmacy Claims for High Cost Oncology Products: Abiraterone and Enzalutamide Usage in Mcrpc in Ireland, Value Health, 19, (7), 2016, ppA754 - A754Poster, 2016
  • Schmitz S, McCullagh L, Dolan E, Walsh C, The Quev Score: A Quantitative Evaluation of the Quality of Clinical Evidence in HTA, Value Health, 19, (7), 2016, ppA499 - A499Poster, 2016
  • Gorry C, McCullagh M, Barry M, Drug Utilisation of Braf Inhibitors for Melanoma in Ireland, Value Health, 19, (7), 2016, ppA728 - A728Poster, 2016
  • O'Donnell H, McCullagh L, Barry M, The Potential Budget Impact of PCSK9 Inhibitors in Ireland, Value Health, 2016, 7, (19), 2016, ppA643 - A643Poster, 2016
  • Dolan E, Schmitz S, Barry M, McCullagh L, Movement of Drugs for Cancer Through The Pharmacoeconomic Evaluation Process in Ireland: Consideration Given to The Quality of Clinical Evidence, Value Health, 2016, 19, (7), 2016, ppA757 - A757Poster, 2016, DOI
  • McCullagh L, Schmitz S, Barry M, Walsh C, Examining the Feasibility and Utility of Estimating Partial Expected Value of Perfect Information (via a Nonparametric Approach) as Part of the Reimbursement Decision-Making Process in Ireland: Application to Drugs for Cancer, PharmacoEconomics, 2017Journal Article, 2017, DOI
  • Corcoran A, Hickey N, Barry M, Usher C, McCullagh L, Ivacaftor for cystic fibrosis; An evaluation of real world utilisation and expenditure in the Irish Healthcare Setting., Irish Medical Journal, 110, (8), 2017Journal Article, 2017, URL
  • Gorry C, McCullagh L, O'Donnell H, Barrett S, Schmitz S, Barry M, Curtin K, Beausang E, Barry R, Coyne I. , Neoadjuvant Treatment for malignant and metastatic melanoma. , Cochrane Database of Systematic Reviews. , (3), 2018Journal Article, 2018, DOI , URL
  • Cardwell K, Clyne B, Moriarty F, Wallace E, Fahey T, Boland F, McCullagh L, Clarke S, Finnigan K, Daly M , Barry M, Smith, S , Supporting prescribing in Irish primary care: Protocol for a non-randomised pilot study of a general practice pharmacist (GPP) intervention to optimise prescribing in primary care., Pilot and Feasibility Studies, 4, (122), 2018Journal Article, 2018, DOI
  • Gorry, Claire and Leahy, Joy and Lamrock, Felicity and Walsh, Cathal and White, Arthur and Barry, Michael and McCullagh, Laura, VP82 Impact of Evidence Synthesis Methods on Outcome of Economic Evaluation, International Journal of Technology Assessment in Health Care, 35, (S1), 2019, p93 - 94Journal Article, 2019, DOI
  • Abdelaal Ahmed Mahmoud M Alkhatip, A., Conroy, P., Hamza, M.K., Murphy, I., Purcell, A., McGuire, D., The authors reply, Critical Care Medicine, 48, (8), 2020, pE731-E732Journal Article, 2020
  • Karen Cardwell, Susan M Smith, Barbara Clyne, Laura McCullagh, Emma Wallace, Ciara Kirke, Tom Fahey, Frank Moriarty, Evaluation of the General Practice Pharmacist (GPP) intervention to optimise prescribing in Irish primary care: a non-randomised pilot study, 2019Journal Article, 2019, DOI
  • Croke A, Moriarty F, Boland F, McCullagh L, Cardwell K, Smith SM, Clyne B., Integrating clinical pharmacists within general practice: protocol for a pilot cluster randomised controlled trial., BMJ Open, 11, (3), 2021, pe041541Journal Article, 2021, DOI
  • Leahy J, Hickey C, McConnell D, Cassidy O, Trela-Larsen L, Barry M, Tilson L, McCullagh L, NCPE Review Group., Coronavirus Disease 2019: Considerations for Health Technology Assessment From the National Centre for Pharmacoeconomics Review Group., Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 23, (11), 2020, p1423-1426Journal Article, 2020, DOI
  • O'Donnell H, McCullagh L, Barry M, Walsh C., The Interaction between Price Negotiations and Heterogeneity: Implications for Economic Evaluations., Medical decision making : an international journal of the Society for Medical Decision Making, 40, (2), 2020, p144-155Journal Article, 2020, DOI
  • Gorry C, McCullagh L, Barry M., Transferability of Economic Evaluations of Treatments for Advanced Melanoma., PharmacoEconomics, 38, (2), 2020, p217-231Journal Article, 2020, DOI
  • Dominguez Castro P, Reynolds CM, Kennelly S, Clyne B, Bury G, Hanlon D, Murrin C, McCullagh L, Finnigan K, Clarke S, Browne S, Perrotta C, Gibney ER, Corish CA., General practitioners' views on malnutrition management and oral nutritional supplementation prescription in the community: A qualitative study., Clinical nutrition ESPEN, 36, 2020, p116-127Journal Article, 2020, DOI
  • Usher C, McCullagh L, Tilson L, Barry M., Analysis of Health Technology Assessments of Orphan Drugs in Ireland from 2012 to 2017., Pharmacoecon Open, 3, (4), 2019, p583-589Journal Article, 2019, DOI
  • Gorry C, McCullagh L, Barry M., Economic Evaluation of Systemic Treatments for Advanced Melanoma: A Systematic Review., Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 23, (1), 2020, p52-60Journal Article, 2020, DOI
  • Lamrock F, McCullagh L, Tilson L, Barry M., A retrospective analysis of budget impact models submitted to the National Centre for Pharmacoeconomics in Ireland., The European journal of health economics : HEPAC : health economics in prevention and care, 21, (6), 2020, p895-901Journal Article, 2020, DOI
  • Moorkens E, Vulto AG, Huys I, Dylst P, Godman, B, Keuerleber, S Claus B, Dimitrova M McCullagh L et al, Policies for biosimilar uptake in Europe: An overview, ONE, 2017Journal Article, 2017, DOI
  • Evelien Moorkens , Arnold G. Vulto, Isabelle Huys,.....Laura mccullagh et al, Policies for biosimilar uptake in Europe: An overview, PLOS ONE, 2017Journal Article, 2017, DOI
  • O'Donnell H, McCullagh L, Barry, M, Walsh. C. , Negotiating The Relationship Between Price and Volume: Implications for ICER Calculations in Heterogeneous Treatment Populations., 40th Annual Meeting of the Society for Medical Decision Making, Montréal, Québec, Canada, October 13-17, 2018, 2018Poster, 2018, DOI
  • Carey N, McCullagh L, Barry M , Evaluating The Quality And Risk Of Bias In Overall Survival Outcomes From Non-Randomised Car T-Cell Therapy Pivotal Trials , ISPOR Europe , Copenhagen, Denmark, November 2019, 2019Poster, 2019
  • Gorry C, McCullagh L, Barry M, Potential Budget Impact Of Adjuvant Treatments For Stage Iii Melanoma In Ireland , ISPOR Europe, Copenhagen, Denmark, 2019, 2019Poster, 2019, DOI
  • Castro P.D., Reynolds C.M., Kennelly S., Geraghty A.A., Finnigan K., McCullagh L., Gibney E.R., Perrotta C., Corish C.A., An investigation of community-dwelling older adults' opinions about their nutritional needs and risk of malnutrition; a scoping review, Clinical Nutrition, 2021Journal Article, 2021, DOI
  • Gorry, C, Barry, M, McCullagh, L, Analysis Of Hospital Episode Statistics To Identify Hopsital Resource Use Due To Skin Cancer In Ireland, Value in Health, 20, (9), 2017, pA506Journal Article, 2017, DOI
  • Dominguez Castro, Patricia, Reynolds, Ciara, Bizzaro, Maria Gabriella, Kennelly, Sharon, Clyne, Barbara, Bury, Gerard, Bradley, Catriona, Finnigan, Karen, McCullagh, Laura, Murrin, Celine, Perrotta, Carla, Gibney, Eileen R, Corish, Clare A, Characteristics and determinants of high volume dispensing in long-term oral nutritional supplement users in primary care: a secondary analysis, BJGP Open, 2021, pBJGPO.2020.0131Journal Article, 2021, DOI
  • Castro, P. Dominguez, Reynolds, C., Kennelly, S., Clyne, B., Bury, G., Bradley, C., Finnigan, K., McCullagh, L., Barry, M., Murrin, C., Perrotta, C., Gibney, E., Corish, C., "Don"t Go Near The Word Malnutrition"; A qualitative study of community healthcare professionals and patients views on the term malnutrition, Clinical Nutrition ESPEN, 40, 2020, p592Journal Article, 2020, DOI
  • Dominguez Castro, P., Reynolds, C., Bizzaro, M.G., Kennelly, S., Clyne, B., Bury, G., Bradley, C., Finnigan, K., McCullagh, L., Barry, M., Murrin, C., Perrotta, C., Gibney, E., Corish, C., The characteristics of long-term oral nutritional supplement users in Ireland, Clinical Nutrition ESPEN, 40, 2020, p496-497Journal Article, 2020, DOI
  • Kennedy, C., McCullagh, L., Adams, R., Trela-Larsen, L., Tilson, L., Barry, M., PMU52 The Reliability of Budget IMPACT Predictions for Drugs with Incremental Cost Effectiveness Ratios ABOVE the Irish Threshold, Value in Health, 23, 2020, pS612Journal Article, 2020, DOI
  • Warren, E., Fuller, R., Mulkerrin, L., Varley, A., McCullagh, L., Barry, M., PPM5 Health Technology Assessment and Companion Diagnostics: A Review of Submissions to the Ncpe from 2012-2019, Value in Health, 23, 2020, pS687-S688Journal Article, 2020, DOI
  • Reynolds, C.M., Dominguez Castro, P., Bardon, L.A., Kennelly, S., Clyne, B., Bury, G., Bradley, C., Finnigan, K., McCullagh, L., Barry, M., Murrin, C., Perrotta, C., Gibney, E., Corish, C., It Takes A Village: Patient Perspectives On The Management Of Malnutrition In The Community, Clinical Nutrition ESPEN, 40, 2020, p464-465Journal Article, 2020, DOI
  • Dominguez Castro, P., Reynolds, C., Bizzaro, G., Kennelly, S., Clyne, B., Bury, G., Bradley, C., Finnigan, K., McCullagh, L., Barry, M., Murrin, C., Perrotta, C., Gibney, E., Corish, C., Large number of prescribed central nervous system drugs and younger age predict the use of more oral nutritional supplements units, Clinical Nutrition ESPEN, 40, 2020, p496Journal Article, 2020, DOI
  • Reynolds, C.M., Dominguez Castro, P., Kennelly, S., Clyne, B., Bury, G., Bradley, C., Finnigan, K., McCullagh, L., Barry, M., Murrin, C., Perrotta, C., Gibney, E., Healthcare professionals" preferences for the delivery, content and structure of a malnutrition education programme: An exploratory qualitative Study, Clinical Nutrition ESPEN, 40, 2020, p465Journal Article, 2020, DOI
  • Kennedy, C., McCullagh, L., Adams, R., Trela-Larsen, L., Tilson, L., Barry, M., PMU65 Drugs with Incremental Cost Effectiveness Ratios ABOVE the Irish Threshold and Subsequent Price Negotiations, Value in Health, 23, 2020, pS613Journal Article, 2020, DOI
  • Castro, Patricia Domínguez, Kennelly, Sharon, Clyne, Barbara, Bury, Gerard, Bradley, Catriona, Finnigan, Karen, McCullagh, Laura, Barry, Michael, Murrin, Celine, Perrotta, Carla, Villaroel, Katherine Loayza, Reynolds, Ciara, Gibney, Eileen, Corish, Clare, A preliminary qualitative study of general practitioners" views on malnutrition management and oral nutritional supplementation prescription in the community, Proceedings of the Nutrition Society, 79, (OCE2), 2020Journal Article, 2020, DOI
  • Castro, Patricia Domínguez, Kennelly, Sharon, Murrin, Celine, Bradley, Catriona, Clyne, Barbara, Bury, Gerard, Finnigan, Karen, McCullagh, Laura, Barry, Michael, Browne, Sarah, Reynolds, Ciara, Bardon, Laura, Gibney, Eileen, Corish, Clare, A preliminary qualitative study of nurses" and dietitians" views on malnutrition management and oral nutritional supplementation prescription in the community, Proceedings of the Nutrition Society, 79, (OCE2), 2020Journal Article, 2020, DOI
  • Gorry, C., Leahy, J., Lamrock, F., Barry, M., McCullagh, L., PCN184 ECONOMIC EVALUATION OF CHECKPOINT INHIBITORS FOR THE TREATMENT OF ADVANCED MELANOMA IN THE IRISH HEALTHCARE SETTING, Value in Health, 22, 2019, pS471-S472Journal Article, 2019, DOI
  • Lee, A., Tan, S., Usher, C., Barry, M., McCullagh, L., PNS181 SUBMISSIONS TO A NATIONAL HTA AGENCY IN IRELAND: DRUGS WITH DESIGNATED ORPHAN STATUS, Value in Health, 22, 2019, pS792Journal Article, 2019, DOI
  • Trela-Larsen, L., Usher, C., McCullagh, L., Barry, M., Walsh, C., PCN498 REAL-WORLD EVIDENCE ON THE UTILISATION OF ABIRATERONE AND ENZALUTAMIDE IN IRELAND, Value in Health, 22, 2019, pS534Journal Article, 2019, DOI
  • Carey, N., McCullagh, L., Barry, M., PCN6 EVALUATING THE QUALITY AND RISK OF BIAS IN OVERALL SURVIVAL OUTCOMES FROM NON-RANDOMISED CAR T-CELL THERAPY PIVOTAL TRIALS, Value in Health, 22, 2019, pS436Journal Article, 2019, DOI
  • Carey, Niamh, Harte, Marie, Gorry, Claire, McCullagh, Laura, OP136 Provision Of A Chimeric Antigen Receptor T-Cell Program: A Rapid Review, International Journal of Technology Assessment in Health Care, 35, (S1), 2019, p31-31Journal Article, 2019, DOI
  • Maguire, Orla, McCullagh, Laura, Usher, Cara, Barry, Michael, OP65 Pharmacoeconomic Evaluation Of Orphan Drugs: Impact Of Extra Criteria?, International Journal of Technology Assessment in Health Care, 35, (S1), 2019, p16-16Journal Article, 2019, DOI
  • McCabe, L., Moloney, D., Barry, M., Usher, C., McCullagh, L., PCN272 - ANALYSIS OF PHARMACY CLAIMS FOR HIGH COST DRUGS: LENALIDOMIDE UTILISATION AND EXPENDITURE IN IRELAND, Value in Health, 21, 2018, pS60Journal Article, 2018, DOI
  • Hickey, N, Corcoran, A, Usher, C, Barry, M, McCullagh, L, Analysis Of Pharmacy Claims For High Cost Drugs: Ruxolitinib Utilisation And Expenditure In Ireland, Value in Health, 20, (9), 2017, pA462Journal Article, 2017, DOI
  • Carey, N, McCullagh, L, Barry, M, Tilson, L, PRM272 - THE EUNETHTA TRANSFERABILITY TOOL: APPLICATION TO NOVEL TREATMENTS FOR RELAPSED REFRACTORY MULTIPLE MYELOMA IN THE IRISH HEALTHCARE SETTING, Value in Health, 21, 2018, pS402-S403Journal Article, 2018, DOI
  • , Partial EVPI feasible as part of HTA in Ireland, PharmacoEconomics & Outcomes News, 785, (1), 2017, p25-25Journal Article, 2017, DOI
  • Kennedy, Cormac, McCullagh, Laura, Adams, Roisin, Trela-Larsen, Lea, Tilson, Lesley, Barry, Michael, Estimating the Theoretical Cost Implications of Funding New Drugs Considered Not to Be Cost-Effective, Value in Health, 2021Journal Article, 2021, DOI
  • Castro, P.D., Reynolds, C.M., Kennelly, S., Geraghty, A.A., Finnigan, K., McCullagh, L., Gibney, E.R., Perrotta, C., Corish, C.A., An investigation of community-dwelling older adults' opinions about their nutritional needs and risk of malnutrition; a scoping review, Clinical Nutrition, 2021Journal Article, 2021, DOI
  • James, O., Cardwell, K., Moriarty, F., M Smith, S., Clyne, B., Barry, M., Boland, F., Clarke, S., Finnigan, K., Daly, M., McCullagh, L., Wallace, E., Kirke, C., Bradley, C., Gallagher, P., Murphy, E., Byrne, A.M.P., Croke, A., Fahey, T., Pharmacists in general practice: A qualitative process evaluation of the General Practice Pharmacist (GPP) study, Family Practice, 37, (5), 2020, p711-718Journal Article, 2020, DOI
  • Varley Á, Tilson L, Fogarty E, McCullagh L, Barry M., The Utility of a Rapid Review Evaluation Process to a National HTA Agency., PharmacoEconomics, 2021Journal Article, 2021, DOI
  • Carey N, Harte M, Mc Cullagh L., A text-mining tool generated title-abstract screening workload savings: performance evaluation versus single-human screening., Journal of clinical epidemiology, 149, 2022, p53-59Journal Article, 2022, DOI
  • Carey N, Leahy, J, Trela-Larsen L, McCullagh L., & Barry, M, Tisagenlecleucel for relapsed/refractory acute lymphoblastic leukemia in the Irish healthcare setting: Cost-effectiveness and value of information analysis. , International Journal of Technology Assessment in Health Care,, 38, (1 e56), 2022, p1 - 11Journal Article, 2022, DOI
  • Niamh Carey, Joy Leahy, Lea Trela-Larsen, Laura Mc Cullagh, Michael Barry, Cost-utility and value of information analysis of tisagenlecleucel for relapsed/refractory diffuse large B-cell lymphoma in the Irish healthcare setting, Journal of Market Access & Health Policy, 11, (1), 2023Journal Article, 2023, DOI
  • Claire Gorry, Laura McCullagh, Helen O'Donnell, Sarah Barrett, Susanne Schmitz, Michael Barry, Kay Curtin, Eamon Beausang, Rupert Barry, Imelda Coyne, Neoadjuvant treatment for stage III and IV cutaneous melanoma, Cochrane Database of Systematic Reviews, 2023, (1), 2023, p1 - 102Journal Article, 2023, TARA - Full Text
  • Croke A, Cardwell K, Clyne B, Moriarty F, McCullagh L, Smith SM., The effectiveness and cost of integrating pharmacists within general practice to optimize prescribing and health outcomes in primary care patients with polypharmacy: a systematic review., BMC Prim Care, 24, (1), 2023, p41Journal Article, 2023, DOI
  • Rosealeen Barrett, Michael Barry, Laura McCullagh, Health technology management: the experience of a managed access approach to the reimbursement of dupilumab in Ireland, Irish Journal of Medical Science (1971 -), 2023Journal Article, 2023, DOI
  • Cassidy O, Harte M, Trela-Larsen L, Walsh C, White A, McCullagh L, Leahy J., A comparison of relative-efficacy estimate(s) derived from both Matching-Adjusted Indirect Comparisons and Standard Anchored Indirect Treatment Comparisons., Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2023, pS1098-3015(23)03061-9Journal Article, 2023, DOI
  • O'Callaghan J, Tilson L, Fogarty E, McCullagh L , Clinical expert opinion to inform Health Technology Assessments., Irish Medical Journal, 116, (8), 2023Journal Article, 2023
  • Clarke S, Delamere S, McCullagh L, Hoskins S, Bergin C, Mulcahy F, Assessing limiting factors to the acceptance of antiretroviral therapy in a large cohort of injecting drug users, HIV Med, 4, (1), 2003, p33 - 37Journal Article, 2003, DOI
  • Hopkins S, Lambourne J, Farrell G, McCullagh L, Hennessy M, Clarke S, Mulcahy F, Bergin C., Role of individualization of hepatitis C virus (HCV) therapy duration in HIV/HCV-coinfected individuals., HIV Med. , 7, (4), 2006, p248-54.Journal Article, 2006, DOI , URL
  • McCullagh L, Walsh C, Barry M , Value-of-Information Analysis to Reduce Decision Uncertainty Associated with the Choice of Thromboprophylaxis after Total Hip Replacement in the Irish Healthcare Setting., PharmacoEconomics, 30, (10), 2012, p941 - 959Journal Article, 2012, DOI
  • O'Brien C, Fogarty E, Walsh C, Dempsey O, Barry M, Kennedy MJ, McCullagh L, The cost of the inpatient management of febrile neutropenia in cancer patients - a micro-costing study in the Irish healthcare setting. , European Journal of Cancer Care, 2014Journal Article, 2014, DOI

Research Expertise

Dr McCullagh is Chief I Pharmacist, Head of Research, NCPE and Clinical Senior Lecturer, Trinity College Dublin. She has been the lead on over 50 HTA evaluations of drugs for which reimbursement by the HSE is sought. Each report details comparative-effectiveness, cost-effectiveness and the expected budget impacts of the drug under consideration. The reports inform the HSE reimbursement decision-making process. Dr McCullagh has published research undertaken in HTA, including: comparative clinical-effectiveness and cost-effectiveness of drugs, evidence synthesis (for comparative-efficacy), value-of-information analysis, multiple-criteria-decision analysis, survival analysis (of immature clinical-trial data), cost of health-care and analysis of drug utilisation and prescribing & expenditure trends. Dr McCullagh is a co-applicant on a number of research grants. She is a member of the HEALED consortium funded under the Disruptive Technologies Innovation Fund, Department of Enterprise and Innovation, Ireland. Here she is leading the HTA of novel immunotherapies for the treatment of cancers. She was a co-applicant on a Health Research Board (HRB) Applied-Partnership Award which examined how drug utilisation and outcomes analyses can inform HTA and reimbursement. A HRB RCQPS Award investigated how a GP practice-based Pharmacist Medicines Optimisation Programme supports prescribing in primary care. A HRB RCQOS Award investigated how a multi-disciplinary prescribing strategy supports prescribing of oral nutritional supplements by GPs. Previously, she was a HRB Interdisciplinary Capacity Enhancement research fellow at Trinity College Dublin. This research programme investigated novel approaches to cancer prevention, treatment and cost in conjunction with the National Cancer Registry of Ireland and the NCPE. Dr McCullagh publishes research in top-in-filed, European and International peer-reviewed journals and conferences. She is a member of the Editorial Boards of PharmacoEconomics and Frontiers in Medicine. She provides peer-review for heath-economics and clinical journals, for the Medical Research Council, UK and the Veni Scheme, Netherlands Organization for Scientific Research. She is on the ISPOR Europe Research Programme Committee. She is on the Research Ethics Committee, Health Policy and Management-Centre for Global Health, Trinity College Dublin. Dr McCullagh supervises Post-doctoral, PhD, MD, MSc and undergraduate research. She is a member of the Health Policy and Management-Centre for Global Health REC, Trinity College Dublin.

Recognition

  • 'Boots' The Chemist Prize, for Highest Academic Grades in First Year of Pharmacy Undergrad Degree, University of Sunderland, UK. 1989
  • 'Mawson Proctor' Award for Highest Academic Grades in Pharmaceutical Chemistry & Pharmacognosy (Pharmacy), University of Sunderland, UK. 1990
  • 'Murdoch McKenzie' Prize for Highest Academic Grades in Pharmacy Undergrad Degree (1989-1991 inclusive), University of Sunderland, UK. 1991
  • Member of The Pharmaceutical Society of Ireland.
  • Member of The Royal Pharmaceutical Society of Great Britain. 1998
  • Member, National Cancer Control Programme (NCCP) Technology Review Group. 2015
  • Member, National Prostate Cancer Research Consortium 2014
  • Member, Irish Cancer Epidemiology Network (ICEN). 2018
  • Member, HIQA Expert Advisory Group, HTA Assessment of National Screening Programme for Atrial Fibrillation 2015
  • Peer-review for European and international top-in field journals (HTA and clinical). External peer-review for the Innovational Research Incentive Scheme - Veni, Netherlands Organisation for Scientific Research. 2010 - date
  • Ireland Representative (medicinal products), Health Technology Assessment Coordination Group (HTACG), European Commission. 2023
  • Editorial Board, Frontiers in Medicine 2023 - date
  • Lead, Development & Implementation of HTA Module, National Annual Patient Education Programme in Health Innovation, EUPATI for Irish Patient Communities (in association with IPPOSI) 2017 - date
  • Lead HTA Assessor, Senior Management, Head of Research, NCPE 2008 - date
  • Member, The Piperska Group, a pan-European collaborative aiming to address/advance pharmaceutical-related financial sustainability of healthcare systems 2013
  • Joint Clinical Assessment Subgroup, Health Technology Assessment Coordination Group, European Commission. 2023 - date
  • Editorial Board, PharmacoEconomics 2020 - date
  • ISPOR Europe Programme Committee Member 2021 - date