Research

Single molecule manipulation and biosensing using optical tweezer and MEMS diagnostic technology - Bioanalytics @ Molecular Level

Sensing Tools for Nano-Systems Investigations

 

Optical Tweezers

Optical Tweezers

Force resolution 0.1 pN - 200pN
Position Resolution 0.1 nm 

Projects: Single Molecule mechanics and spectroscopy:
Current highlights: VirE2 dynamics dsDNA Mechanics (pdf),
Mitochondria import, Ribosomal mechanics  

 

Scanning Force Microscopy

Scanning Force Microscopy

Force resolution 10 pN - 4nN
Position Resolution 0.1 nm

Projects: Single Molecule mechanics and spectroscopy:
Recent project: Nanomechanical Protein Folding (pdf)

 

Sensing Tools for Macro-Systems Investigations 

 

Nanomechanical Cantilever Arrays

Nanomechanical Cantilever Arrays

pN Interaction Forces transduced into nanomechanical motion
Position Resolution 0.1 nm 

Projects: Gene fishing, Proteomics sensors, Microorganism
sensors, Membrane protein sensors, Ion sensors, Gas sensors.
Current highlight: Tiny Springboards detect Viruses in Fluids

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