About



Location: CRANN building 2.39

The Nano-Biological laboratory managed by Dr. Nigel Carroll is purpose built and is dedicated to interdisciplinary research at the interface between the physical and life sciences.

The research activities include investigation of cellular interactions using novel biophysical tools such as in vitro pulsed magnetic stimulation (TMS) of neuron networks and bio-magnetic detection using advanced magnetoresistive sensors for applications such as detecting magnetically-labeled biomarkers and magnetic flow cytometery

The research activities include investigation of cellular interactions using novel biophysical tools such as in vitro pulsed magnetic stimulation (TMS) of neuron networks and bio-magnetic detection using advanced magnetoresistive sensors for applications such as detecting magnetically-labeled biomarkers and magnetic flow cytometery.

Equipment

Type

 

Cell culture flow hood

Telstar Bio-II-A/G Bio-flow hood

 

C02 Incubator

Thermo Electron Corporation C02 Incubator

 

Centrifuge

Universal 320: Centrifuge

 

Sterilizer Autoclave

Tomy: SX-700E High pressure steam Sterilizer

 

Refrigerator & freezer

ULTF80 Deep fridge MyBio Dairei

 

Ice  maker

 

 

pH Meter

 

 

Water bath

Gant

 

Microscope

  • Olympus: CKX41 Microscope
  • Olympus: U-RFL-T (Light source)

 

Camera

QIMAGING: Camera type: 01-QIClick-R-F-M-12

 

Cell culture vessels

  • Flasks, Petri dishes, roller bottles, multiwell plates)
  • Pipettes and pipettors
  • Syringes and needles
  • Waste containers
  • Media, sera, and reagents



Cell culture vessels

• Flasks, Petri dishes, roller bottles, multiwell plates)
• Pipettes and pipettors
• Syringes and needles
• Waste containers
• Media, sera, and reagents



Laboratory platform equipment

EquipmentType
Manipulators • Sutter Instrument Company: MP-225 manipulator controller
• Sutter Instrument Company: MP-225 manipulator controller
• Wentworth laboratories: Manipulator type: SPM195 Qty:2
TMS test bead Transcranial magnetic stimulator
T&M equipment • Stanford research Type: SR560 Low noise pre-amplifier
• Glassman: High voltage supply ER series 10 kV 30 mA
• Kepco: Bipolar operational supply 50 V 2 A
Permanent magnets • 1 T Magnetic solutions diameter 19 cm
• 88 mT Magnetic solutions diameter 22 cm
• 49 mT Magnetic solutions diameter 23 cm
Gauss meter  

Projects



Magnetoresistive detection platform for biological applications
Bio-magnetic detection using advanced magnetoresistive sensors for applications such as detecting magnetically-labeled biomarkers and magnetic flow cytometery

Dr Nigel Caroll Nanobio Lab image

Pulse magnetic stimulator platform for biological applications
Transcranial Magnetic Stimulation (TMS) of the nervous system has been an important tool in neuroscience for over twenty years. More recently many clinical applications have also been developed for diseases such as Multiple Sclerosis and Parkinson’s disease. The aims for this work is to elucidate the physical and biochemical mechanisms involved the in vitro magnetic stimulation of neuron and to measure TMS effects on neuronal development and neurotransmitter release


Dr Nigel Caroll Nanobio Lab image