Medicine

Contact Us School of Medicine
Level 1
Trinity Biomedical Sciences Institute
Trinity College
152-160 Pearse Street
Dublin 2

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medadmin@tcd.ie
Dr. Thomas Ryan

Dr. Thomas Ryan

Clinical Senior Lecturer, Surgery

3531 4162516http://people.tcd.ie/ryanth

Publications and Further Research Outputs

  • O'Connor, G. Ryan, T. Redmond, J. Doherty, C., The value of motor response versus neuroimaging in predicting outcome post cardiac arrest: A retrospective study, Journal of Neurology, 257, (8), 2010, p1400 - 1401Journal Article, 2010, DOI , URL
  • Leahy TR, McManus R, Doherty DG, Grealy R, Coulter T, Smyth P, Blackshields G, Sheils O, Carr MJ, Purandare N, Geary M, Hodemaekers HM, Janssen R, Bont L, Slattery D, Ryan T, Interleukin-15 is associated with disease severity in viral bronchiolitis., 2015Journal Article, 2015
  • Conroy MJ, Mac Nicholas R, Grealy R, Taylor M, Otegbayo JA, O'Dea S, Mulcahy F, Ryan T, Norris S, Doherty DG, Circulating CD56dim natural killer cells and CD56+ T cells that produce interferon-" or interleukin-10 are expanded in asymptomatic, E antigen-negative patients with persistent hepatitis B virus infection., Journal of viral hepatitis, 22, (3), 2015, p335-45Journal Article, 2015, DOI
  • Eleanor Molloy, Michelle Walsh, Response, J Perinatol, 25, (5), 2005, p360--360Journal Article, 2005
  • Rady, M.Y., Ryan, T., Starr, N.J., Preoperative therapy with amiodarone and the incidence of acute organ dysfunction after cardiac surgery, Anesthesia and Analgesia, 85, (3), 1997, p489-497Journal Article, 1997
  • Higgins, T.L., Yared, J.-P., Ryan, T., Immediate postoperative care of cardiac surgical patients, Journal of Cardiothoracic and Vascular Anesthesia, 10, (5), 1996, p643-658Journal Article, 1996
  • Ryan, T., Burwash, I., Lu, J., Otto, C., Graham, M., Verrier, E., Spiess, B.D., The agreement between ventricular volumes and ejection fraction by transesophageal echocardiography or a combined radionuclear and thermodilution technique in patients after coronary artery surgery, Journal of Cardiothoracic and Vascular Anesthesia, 10, (3), 1996, p323-328Journal Article, 1996
  • Ryan, T., Mannion, D., O'Brien, W., Grace, P., Bouchier-Hayes, D., Cunningham, A.J., Spinal cord perfusion pressure in dogs after control of proximal aortic hypertension during thoracic aortic cross-clamping with esmolol or sodium nitroprusside, Anesthesiology, 78, (2), 1993, p317-325Journal Article, 1993
  • Ryan, T., Timoney, A., Cunningham, A.J., Use of transoesophageal echocardiography to manage beta-adrenoceptor block and assess left ventricular function in a patient with phaeochromocytoma, British Journal of Anaesthesia, 70, (1), 1993, p101-103Journal Article, 1993
  • Ryan, T., Page, R., Bouchier-Hayes, D., Cunningham, A.J., Transoesophageal pulsed wave Doppler measurement of cardiac output during major vascular surgery: Comparison with the thermodilution technique, British Journal of Anaesthesia, 69, (1), 1992, p101-104Journal Article, 1992
  • O'Dwyer, M.J., Duggan, E., Ryan, T., Letter regarding article by Tomic et al, "transcriptomic and proteomic patterns of systemic inflammation in on-pump and off-pump coronary artery bypass grafting" [1], Circulation, 113, (19), 2006Journal Article, 2006
  • Duggan, E., Caraher, E., Gately, K., O'Dwyer, M., McGovern, E., Kelleher, D., McManus, R., Ryan, T., Tumor necrosis factor-" and interleukin-10 gene expression in peripheral blood mononuclear cells after cardiac surgery, Critical Care Medicine, 34, (8), 2006, p2134-2139Journal Article, 2006
  • Bashour, C.A., Yared, J.-P., Ryan, T.A., Rady, M.Y., Mascha, E., Leventhal, M.J., Starr, N.J., Long-term survival and functional capacity in cardiac surgery patients after prolonged intensive care, Critical Care Medicine, 28, (12), 2000, p3847-3853Journal Article, 2000
  • Rady, M.Y., Ryan, T., Perioperative predictors of extubation failure and the effect on clinical outcome after cardiac surgery, Critical Care Medicine, 27, (2), 1999, p340-347Journal Article, 1999
  • Rady, M.Y., Ryan, T., Starr, N.J., Perioperative determinants of morbidity and mortality in elderly patients undergoing cardiac surgery, Critical Care Medicine, 26, (2), 1998, p225-235Journal Article, 1998
  • Rady, M.Y., Kodavatiganti, R., Ryan, T., Perioperative predictors of acute acalculous cholecystitis after cardiac surgery, Critical Care Medicine, 26, (1 SUPPL.), 1998Journal Article, 1998
  • Rady, M.Y., Kodavatiganti, R., Ryan, T., Perioperative predictors of acute cholecystitis after cardiovascular surgery, Chest, 114, (1), 1998, p76-84Journal Article, 1998
  • Barie, P.S., Hydo, L., Ryan, T., Rady, M.Y., Scoring organ dysfunction [1] (multiple letters), Chest, 114, (3), 1998, p941-942Journal Article, 1998
  • Gordon, S.M., Serkey, J.M., Keys, T.F., Ryan, T., Fatica, C.A., Schmitt, S.K., Borsh, J.A., Cosgrove III, D.M., Yared, J.-P., Secular trends in nosocomial bloodstream infections in a 55-bed cardiothoracic intensive care unit, Annals of Thoracic Surgery, 65, (1), 1998, p95-100Journal Article, 1998
  • Rady, M.Y., Ryan, T., The effects of preoperative therapy with angiotensin-converting enzyme inhibitors on clinical outcome after cardiovascular surgery, Chest, 114, (2), 1998, p487-494Journal Article, 1998
  • Rady, M.Y., Ryan, T., Starr, N.J., Clinical characteristics of preoperative hypoalbuminemia predict outcome of cardiovascular surgery, Journal of Parenteral and Enteral Nutrition, 21, (2), 1997, p81-90Journal Article, 1997
  • Ryan, T., Mc Carthy, J.F., Rady, M.Y., Serkey, J., Gordon, S., Starr, N.J., Cosgrove, D.M., Early bloodstream infection after cardiopulmonary bypass: Frequency rate, risk factors, and implications, Critical Care Medicine, 25, (12), 1997, p2009-2014Journal Article, 1997
  • Rady, M.Y., Ryan, T., Erratum: The effects of preoperative therapy with angiotensin-converting enzyme inhibitors on clinical outcome after cardiovascular surgery (Chest (1998) 114 (487-794)), Chest, 114, (4), 1998Journal Article, 1998
  • Rady, M.Y., Ryan, T., Starr, N.J., Early onset of acute pulmonary dysfunction after cardiovascular surgery: Risk factors and clinical outcome, Critical Care Medicine, 25, (11), 1997, p1831-1839Journal Article, 1997
  • Ryan, T.A., Rady, M.Y., Bashour, C.A., Leventhal, M., Lytle, B., Starr, N.J., Predictors of outcome in cardiac surgical patients with prolonged intensive care stay, Chest, 112, (4), 1997, p1035-1042Journal Article, 1997
  • Larkin, C.M., Santos-Martinez, M.-J., Ryan, T., Radomski, M.W., Sepsis-associated thrombocytopenia, Thrombosis Research, 141, 2016, p11-16Review Article, 2016, DOI
  • Jonker, W.R., Hanumanthiah, D., Ryan, T., Cook, T.M., Pandit, J.J., O'Sullivan, E.P., Who operates when, where and on whom? A survey of anaesthetic-surgical activity in Ireland as denominator of NAP5, Anaesthesia, 69, (9), 2014, p961-968Journal Article, 2014
  • McKenny, M., Ryan, T., Tate, H., Graham, B., Young, V.K., Dowd, N., Age of transfused blood is not associated with increased postoperative adverse outcome after cardiac surgery, British Journal of Anaesthesia, 106, (5), 2011, p643-649Journal Article, 2011
  • Frohlich, S., Ryan, T., Fagan, C., Statin therapy associated with fatal rhabdomyolysis, Journal of the Intensive Care Society, 12, (1), 2011, p40-42Journal Article, 2011
  • Mahabeleshwar, G., Kawanami, D., Sharma, N., Takami, Y., Zhou, G., Shi, H., Nayak, L., Jeyaraj, D., Grealy, R., White, M., McManus, R., Ryan, T., Leahy, P., Lin, Z., Haldar, S., Atkins, G., Wong, H., Lingrel, J., Jain, M., The Myeloid Transcription Factor KLF2 Regulates the Host Response to Polymicrobial Infection and Endotoxic Shock, Immunity, 34, (5), 2011, p715-728Journal Article, 2011
  • Mahabeleshwar, G.H., Kawanami, D., Sharma, N., Takami, Y., Zhou, G., Shi, H., Nayak, L., Jeyaraj, D., Grealy, R., White, M., McManus, R., Ryan, T., Leahy, P., Lin, Z., Haldar, S.M., Atkins, G.B., Wong, H.R., Lingrel, J.B., Jain, M.K., The myeloid transcription factor KLF2 regulates the host response to polymicrobial infection and endotoxic shock, Immunity, 35, (1), 2011Journal Article, 2011
  • Ryan, A.W., Hughes, D.A., Tang, K., Kelleher, D.P., Ryan, T., McManus, R., Stoneking, M., Natural selection and the molecular basis of electrophoretic variation at the coagulation F13B locus, European Journal of Human Genetics, 17, (2), 2009, p219-227Journal Article, 2009
  • O'Dwyer, M.J., Mankan, A.K., Ryan, A.W., Lawless, M.W., Stordeur, P., Kelleher, D., McManus, R., Ryan, T., Characterization of tumour necrosis factor-alpha genetic variants and mRNA expression in patients with severe sepsis, International Journal of Immunogenetics, 35, (4-5), 2008, p279-285Journal Article, 2008
  • Duggan, E., Ryan, T., Coagulopathy after cardiac surgery [18], Anesthesia and Analgesia, 105, (5), 2007, p1514-1515Journal Article, 2007
  • Rowan, M., Ryan, T., Hegarty, F., O'Hare, N., The use of artificial neural networks to stratify the length of stay of cardiac patients based on preoperative and initial postoperative factors, Artificial Intelligence in Medicine, 40, (3), 2007, p211-221Journal Article, 2007
  • Leahy T.R, McManus R, Doherty D.G, Grealy R, Carr M.J, Slattery D, Ryan T, Viral Bronchiolitis is Associated with Altered Cytokine Gene Expression and Lymphocyte Activation Status, Pediatric Infectious Disease Journal, 35, (11), 2016, pp e326-e338Journal Article, 2016, DOI , URL
  • Talento AF , Dunne K , Joyce EA , Palmer M , Johnson E , White PL , Springer J, Loeffler J, Ryan T, Collins, Rogers TR, A prospective study of fungal biomarkers to improve management of invasive fungal diseases in a mixed specialty critical care unit., Journal of Critical Care, (40), 2017, p119 - 127Journal Article, 2017
  • Rocha, C. and Woodward, M., Nutrients, 2012, 197-221ppBook, 2012, DOI , URL
  • Larkin CM, Breen EP, Tomaszewski KA, Eisele S, Radomski MW, Ryan TA, Santos-Martinez MJ, Platelet microaggregation in sepsis examined by quartz crystal microbalance with dissipation technology., Platelets, 29, (3), 2018, p301 - 304Journal Article, 2018, DOI
  • Ryan, T., Coakley, J.D., Martin-Loeches, I., Defects in innate and adaptive immunity in patients with sepsis and health care associated infection, Annals of Translational Medicine, 5, (22), 2017Journal Article, 2017
  • J. McGinley, D. J. McCabe, A. Fraser, E. Casey, T. Ryan and R. Murphy, Hashimoto's encephalopathy; an unusual cause of status epilepticus, Irish medical journal, 93, (4), 2000, p118Journal Article, 2000, URL
  • T. Ryan, J. Balding, E. M. McGovern, J. Hinchion, W. Livingstone, Z. Chughtai and O. P. Smith, Lactic acidosis after cardiac surgery is associated with polymorphisms in tumor necrosis factor and interleukin 10 genes, The Annals of thoracic surgery, 73, (6), 2002, p1905-9; discussion 1910-1Journal Article, 2002, URL
  • O'Dwyer MJ, Mankan AK, Stordeur P, O'Connell B, Duggan E, White M, Kelleher DP, McManus R, Ryan T, The occurrence of severe sepsis is related to distinct patterns of cytokine gene expression, Shock, 26, (6), 2006, p544 - 550Journal Article, 2006, DOI
  • Ryan R*, Thornton J*, Duggan E, McGovern E, O'Dwyer MJ, Ryan AW, Kelleher D, McManus R, Ryan T, Gene polymorphism and requirement for vasopressor infusion after cardiac surgery, Annals of Thoracic Surgery, 82, (3), 2006, p895 - 901Journal Article, 2006, DOI
  • Hodgson A, Ryan T, Moriarty J, Mellotte G, Murphy C, Smith OP, Plasma exchange as a source of protein C for acute onset protein C pathway failure, Br J Haematol., 116, (4), 2002, p905 - 908Journal Article, 2002
  • O'Dwyer MJ, Dempsey F, Crowley V, Kelleher DP, McManus R, Ryan T., Septic shock is correlated with asymmetrical dimethyl arginine levels, which may be influenced by a polymorphism in the dimethylarginine dimethylaminohydrolase II gene: a prospective observational study., Critical Care, 10, (5), 2006, pR139Journal Article, 2006, DOI , TARA - Full Text
  • O'Dwyer MJ, Mankan AK, Stordeur P, O'Connell B, Duggan E, White M, Kelleher DP, McManus R, Ryan T., The occurrence of severe sepsis and septic shock are related to distinct patterns of cytokine gene expression., Shock, 26, (6), 2006, p544 - 550Journal Article, 2006
  • Duggan E, O'Dwyer M, Caraher E, Diviney D, McGovern E, Kelleher D, McManus R, Ryan T, Coagulopathy After Cardiac Surgery May Be Influenced by a Functional Plasminogen Activator Inhibitor Polymorphism, Anesthesia & Analgesia , 104, (6), 2007, p1343 - 1347Journal Article, 2007, DOI , TARA - Full Text
  • O'Dwyer MJ, Dempsey F, Crowley V, Kelleher D, McManus R, Ryan T., Septic shock correlates with ADMA levels which may be influenced by a polymorphism in DDAH II: a prospective observational study, Critical Care, 10, (5), 2006, pR139 article numberJournal Article, 2006, DOI
  • O'Dwyer MJ, Mankan AK, Stordeur P, White W, Lawless MW, O'Connell B, Kelleher D, McManus R*, Ryan T* , Variability in IL-23 and IL-27 gene expression may determine patient response to a septic insult, Intensive Care Medicine, 34, (4), 2008, p683 - 691Journal Article, 2008, DOI
  • White M, Mankan A, Lawless MW, O'Dwyer MJ, McManus R, Ryan T, Mortality in humans with pneumonia and sepsis is related to an uncompensated anti-inflammatory response to infection, Archives of Internal Medicine, 168, (13), 2008, p1468 - 1469Journal Article, 2008, URL
  • O'Dwyer MJ, Mankan AK, Stordeur P, White W, Lawless MW, O'Connell B, Kelleher D, McManus R*, Ryan T*. , The human response to infection is associated with distinct patterns of interleukin 23 and interleukin 27 expression, Intensive Care Medicine, 34, (4), 2008, p683-691Journal Article, 2008, DOI
  • Patel KD, Murphy RT, White M, Gasparrow D, Kelleher DP, Ryan T, McManus R, Ryan AW., Interleukin 17: an unlikely marker of acute coronary syndrome?, Atherosclerosis, 205, (1), 2009, p33 - 34Journal Article, 2009
  • White M, Lawless MW, O'Dwyer MJ, Grealy R, O'Connell B, Stordeur P, Kelleher D, McManus R*, Ryan T*, Transforming Growth Factor beta-1 and Interleukin-17 gene transcription in peripheral blood mononuclear cells and the human response to infection, Cytokine, 50, 2010, p322 - 327Journal Article, 2010, DOI
  • White M, Mahon V, Grealy R, Doherty DG, Stordeur P, Kelleher DP, McManus R, Ryan T, Post-operative infection and sepsis in humans is associated with deficient gene expression of Yc cytokines and their apoptosis mediators., Critical Care (London, England), 15, (3), 2011, pR158Journal Article, 2011, DOI , URL , TARA - Full Text
  • Grealy, R., White, M., Stordeur, P., Kelleher, D., Doherty, D.G., McManus, R., Ryan, T., Characterising cytokine gene expression signatures in patients with severe sepsis, Mediators of Inflammation, 2013, 2013, part. no. 164246Journal Article, 2013, DOI , TARA - Full Text
  • White M, Martin-Loeches I, Lawless MW, O'Dwyer MJ, Doherty DG, Young V, Kelleher D, McManus R, Ryan T, Hospital-acquired pneumonia after lung resection surgery is associated with characteristic cytokine gene expression., Chest, 139, (3), 2011, p626-32Journal Article, 2011, DOI