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Recent Student Peer-Reviewed Publications

The impact of exercise during adjuvant radiotherapy for breast cancer on fatigue and quality of life: A systematic review and meta-analysis.

Lipsett A, Barrett S, Haruna F, Mustian K, O'Donovan A.
Breast. 2017 Apr;32:144-155. doi: 10.1016/j.breast.2017.02.002. Epub 2017 Feb 9.

The aim of this study was to assess the effect of exercise (and different exercise prescription parameters) during adjuvant RT on fatigue among breast cancer patients. Quality of life was a secondary outcome. Nine studies (802 participants) were included. The meta-analysis revealed that exercise was statistically more effective at reducing fatigue than the control intervention. Therefore, exercise during adjuvant RT should be encouraged in breast cancer patients. 

Metformin and improved treatment outcomes in radiation therapy – A review

Nur Atiqah Binte Samsuri, Michelle Leech, Laure Marignol. Cancer Treatment Reviews (2017) In press
This review discusses whether metformin should be offered to radiotherapy (RT) cancer patients as a means to improve their treatment outcomes. Three groups of RT cancer patients were analysed: diabetic patients using metformin, diabetic patients not using metformin and non-diabetic patients not using metformin. The analysis of the 13 studies included identified conflicting evidence with regards to the impact of metformin administration on recurrence and survival outcomes following radiotherapy. 

A Review of the Use of Lipiodol and Gold Fiducials for Image Guided Bladder Radiotherapy

Conor Nolan and Elizabeth Forde, Acta Oncologica, 55, (5), 2016, p533 – 538

This review examines the evidence available pertaining to the clinical use of Lipiodol and gold fiducials for image guided radiotherapy (IGRT) for bladder cancer.  Current evidence suggests that Lipiodol injections and gold fiducial markers present as promising and highly accurate methods of overcoming interfraction bladder motion in IGRT.