Professor Declan Mc Loughlin

• Smith KJ, Mullally S, McLoughlin D, O'Mara SM , Validation of the Face-Name Pairs Task in Major Depression: Impaired recall but not recognition. , Frontiers in Psychology , Feb 12;5:92. , 2014Journal Article, 2014
• Lambe S, Mogg A, Eranti A, Pluck G, Hastilow S, McLoughlin DM, Trends in use of electroconvulsive therapy in South London from 1949 to 2006, J ECT, 30, (4), 2014, p309 - 314Journal Article, 2014
• Glaviano A, O'Donovan SM, Ryan KM, O'Mara S, Dunn MJ, McLoughlin DM , Acute phase plasma proteins are altered by electroconvulsive stimulation, J Psychopharmacol , 28, (12), 2014, p1125 - 1134Journal Article, 2014
• Noone M, Semkovska M, Carton M, Dunne R, Horgan JP, O'Kane B, McLoughlin DM , Construction and updating of a public events questionnaire for repeated measures longitudinal studies, Front Psychol, 5:230., 2014Journal Article, 2014, URL , TARA - Full Text
• O'Donovan SM, O'Mara S, Dunn MJ, McLoughlin DM , The persisting effects of electroconvulsive stimulation on the hippocampal proteome, Brain Research , 1593, 2014, p106 - 116Journal Article, 2014
• Semkovska M, Landau S, Dunne R, Kolshus E, Kavanagh A, Jelovac A, Noone M, Carton M, Lambe S, McHugh C, McLoughlin DM., Bitemporal Versus High-Dose Unilateral Twice-Weekly Electroconvulsive Therapy for Depression (EFFECT-Dep): A Pragmatic, Randomized, Non-Inferiority Trial., The American journal of psychiatry, 173, (4), 2016, p408-417Journal Article, 2016, DOI
• Allen AP, Naughton M, Dowling J, Walsh A, Ismail F, Shorten G, Scott L, McLoughlin DM, Cryan JF, Dinan TG, Clarke G., Serum BDNF as a peripheral biomarker of treatment-resistant depression and the rapid antidepressant response: A comparison of ketamine and ECT., Journal of affective disorders, 186, 2015, p306-311Journal Article, 2015, DOI
• Agyapong VI, Osei A, Mcloughlin DM, McAuliffe E., Task shifting-perception of stake holders about adequacy of training and supervision for community mental health workers in Ghana., Health policy and planning, 31, (5), 2016, p645-655Journal Article, 2016, DOI
• Jelovac A, O"Connor S, McCarron S, McLoughlin DM., Autobiographical Memory Specificity in Major Depression Treated With Electroconvulsive Therapy., The journal of ECT, 32, (1), 2016, p38-43Journal Article, 2016, DOI
• Semkovska M, Lambe S, Lonargáin DÓ, McLoughlin DM., Neurocognitive Remediation Therapy for Depression: A Feasibility Study and Randomized Controlled Pilot Protocol Testing., The Journal of nervous and mental disease, 203, (8), 2015, p609-616Journal Article, 2015, DOI
• Hester L, O'Doherty LJ, Schnittger R, Skelly N, O'Donnell M, Butterly L, Browne R, Frorath C, Morgan C, McLoughlin DM, Fearon P., SEQUenCE: a service user-centred quality of care instrument for mental health services., International journal for quality in health care : journal of the International Society for Quality in Health Care, 27, (4), 2015, p284-290Journal Article, 2015, DOI
• Kolshus E, Jelovac A, McLoughlin DM, Bitemporal v. high-dose right unilateral electroconvulsive therapy for depression: a systematic review and meta-analysis of randomized controlled trials - CORRIGENDUM., Psychological medicine, 2018Journal Article, 2018
• Finnegan M, Bayazit H, Cronin T, Guler K, Galligan T, Karababa FI, McLoughlin DM, Towards International Standards: East Meets West., The journal of ECT, 2018Journal Article, 2018
• Brennan S, McLoughlin DM, O'Connell R, Bogue J, O'Connor S, McHugh C, Glennon M, Anodal transcranial direct current stimulation of the left dorsolateral prefrontal cortex enhances emotion recognition in depressed patients and controls., Journal of clinical and experimental neuropsychology, 39, (4), 2017, p384-395Journal Article, 2017, DOI
• Ryan KM, Glaviano A, O'Donovan SM, Kolshus E, Dunne R, Kavanagh A, Jelovac A, Noone M, Tucker GM, Dunn MJ, McLoughlin DM, Electroconvulsive therapy modulates plasma pigment epithelium-derived factor in depression: a proteomics study., Translational psychiatry, 2017Journal Article, 2017
• Kolshus E, Jelovac A, McLoughlin DM, Letter to the Editor: Electrode placement in electroconvulsive therapy - bilateral is still the 'gold standard' for some patients: a reply., Psychological medicine, 2017Journal Article, 2017
• Kolshus E, Jelovac A, McLoughlin DM, Bitemporal v. high-dose right unilateral electroconvulsive therapy for depression: a systematic review and meta-analysis of randomized controlled trials., Psychological medicine, 2017Journal Article, 2017
• Ito M, Bolati K, Kinjo T, Ichimura K, Furuta A, McLoughlin DM, Suzuki T, Arai H, Electroconvulsive stimulation transiently enhances the permeability of the rat blood-brain barrier and induces astrocytic changes., Brain research bulletin, 2017Journal Article, 2017
• Gururajan A, Naughton ME, Scott KA, O'Connor RM, Moloney G, Clarke G, Dowling J, Walsh A, Ismail F, Shorten G, Scott L, McLoughlin DM, Cryan JF, Dinan TG, MicroRNAs as biomarkers for major depression: a role for let-7b and let-7c., Translational Psychiatry, 2016Journal Article, 2016
• McLoughlin DM, Response to Kellner and Farber: Addressing Crossover of High-Dose Right Unilateral ECT to Bitemporal ECT., The American journal of psychiatry, 2016Journal Article, 2016
• Gururajan A, Naughton M, Scott K, Moloney G, Clarke G, Dowling J, Walsh A, Ismail F, Shorten G, Scott L, McLoughlin D, Dinan T, Cryan J, PS193. MicroRNAs as biomarkers for treatment-resistant depression., The international journal of neuropsychopharmacology, 2016Journal Article, 2016
• Finnegan M, Ryan K, Shanahan E, Harkin A, Daly L, McLoughlin DM, Ketamine for depression relapse prevention following electroconvulsive therapy: protocol for a randomised pilot trial (the KEEP-WELL trial)., Pilot and Feasibility Studies, 2016Journal Article, 2016
• Finnegan, M., Galligan, T., Ryan, K., Shanahan, E., Harkin, A., Daly, L., McLoughlin, DM., Ketamine versus midazolam for depression relapse prevention following successful electroconvulsive therapy: a randomized controlled pilot trial., Journal of ECT, 2018Journal Article, 2018, DOI
• Andrew Harkin, Declan M. McLoughlin, Ketamine and depression: A special kase for kynurenic acid?, Brain, Behavior, and Immunity, 2019Journal Article, 2019
• Karen M. Ryan, Declan M. McLoughlin, Peripheral blood GILZ mRNA levels in depression and following electroconvulsive therapy, Psychoneuroendocrinology, 2019Journal Article, 2019
• A.P. Allen, M. Naughton, J. Dowling, A. Walsh, R. O'Shea, G. Shorten, L. Scott, D.M. McLoughlin, J.F. Cryan, G. Clarke, T.G. Dinan, Kynurenine pathway metabolism and the neurobiology of treatment-resistant depression: Comparison of multiple ketamine infusions and electroconvulsive therapy, Journal of Psychiatric Research, 100, 2018, p24--32Journal Article, 2018
• Martha Finnegan, Stephanie O'Connor, Declan M. McLoughlin, Involuntary and voluntary electroconvulsive therapy: A case-control study, Brain Stimulation, 2018Journal Article, 2018
• Karen M. Ryan, Ross Dunne, Declan M. McLoughlin, BDNF plasma levels and genotype in depression and the response to electroconvulsive therapy, Brain Stimulation, 2018Journal Article, 2018
• Declan M McLoughlin, I know not `seems", Australian & New Zealand Journal of Psychiatry, 2018, p000486741877290Journal Article, 2018
• Claire L. McGrory, Karen M. Ryan, Erik Kolshus, Martha Finnegan, Declan M. McLoughlin, Peripheral blood SIRT1 mRNA levels in depression and treatment with electroconvulsive therapy, European Neuropsychopharmacology, 28, (9), 2018, p1015--1023Journal Article, 2018
• Read J, Cunliffe S, Jauhar S, McLoughlin DM., Should we stop using electroconvulsive therapy?, BMJ (Clinical research ed.), 364, 2019, pk5233Journal Article, 2019, DOI
• Ryan KM, Patterson I, McLoughlin DM., Peroxisome proliferator-activated receptor gamma co-activator-1 alpha in depression and the response to electroconvulsive therapy., Psychological medicine, 2018, p1-10Journal Article, 2018, DOI
• Ryan KM, McLoughlin DM., From molecules to mind: mechanisms of action of electroconvulsive therapy., Acta psychiatrica Scandinavica, 138, (3), 2018, p177-179Journal Article, 2018, DOI
• O'Reilly H, Hagerty A, O'Donnell S, Farrell A, Hartnett D, Murphy E, Kehoe E, Agyapong V, McLoughlin DM, Farren C., Alcohol Use Disorder and Comorbid Depression: A Randomized Controlled Trial Investigating the Effectiveness of Supportive Text Messages in Aiding Recovery., Alcohol and alcoholism (Oxford, Oxfordshire), 54, (5), 2019, p551-558Journal Article, 2019, DOI
• Ryan KM, McLoughlin DM., Telomere length in depression and association with therapeutic response to electroconvulsive therapy and cognitive side-effects., Psychological medicine, 2019, p1-11Journal Article, 2019, DOI
• Ryan KM, Allers KA, McLoughlin DM, Harkin A., Tryptophan metabolite concentrations in depressed patients before and after electroconvulsive therapy., Brain, Behavior and Immunity, 83, 2020, p153 - 162Journal Article, 2020, DOI
• Ryan KM, Poelz L, McLoughlin DM., Low Circulating Levels of GR, FKBP5, and SGK1 in Medicated Patients With Depression Are Not Altered by Electroconvulsive Therapy., The journal of ECT, 2019Journal Article, 2019, DOI
• Hartnett Y, Drakeford C, Dunne L, McLoughlin DM, Kennedy N., Physician, heal thyself: a cross-sectional survey of doctors' personal prescribing habits., Journal of medical ethics, 2019Journal Article, 2019, DOI
• Soda T, McLoughlin DM, Clark SR, Oltedal L, Kessler U, Haavik J, Bousman C, Smith DJ, Bioque M, Clements CC, Loo C, Vila-Rodriguez F, Minelli A, Mickey BJ, Milev R, Docherty AR, Langan Martin J, Achtyes ED, Arolt V, Redlich R, Dannlowski U, Cardoner N, Clare E, Craddock N, Di Florio A, Dmitrzak-Weglarz M, Forty L, Gordon-Smith K, Husain M, Ingram WM, Jones L, Jones I, Juruena M, Kirov G, Landén M, Müller DJ, Nordensköld A, Pålsson E, Paul M, Permoda A, Pliszka B, Rea J, Schubert KO, Sonnen JA, Soria V, Stageman W, Takamiya A, Urretavizacaya M, Watson S, Zavorotny M, Young AH, Vieta E, Rybakowski JK, Gennarelli M, Zandi PP, Sullivan PF, Baune BT., International Consortium on the Genetics of Electroconvulsive Therapy and Severe Depressive Disorders (Gen-ECT-ic)., European archives of psychiatry and clinical neuroscience, 2019Journal Article, 2019, DOI
• Ryan K.M., and Allers K.A. and Harkin A. and McLoughlin D.M. , Blood plasma B vitamins in depression and the therapeutic response to electroconvulsive therapy, Brain, Behavior and Immunity Health, 2020Journal Article, 2020, DOI
• Thekiso TB, McLoughlin DM, Hartnett Y, Casey S, Orji A, Heron EA, Rush G, Kennedy N., Outcome of First-admission Depression Treated in a Specialized Mood Disorders Service., Journal of psychiatric practice, 26, (6), 2020, p461-471Journal Article, 2020, DOI
• Celine A. Fox, Declan M. McLoughlin, Speed of electroconvulsive therapy for depression: Effects of electrode placement, Acta Psychiatrica Scandinavica, 2021Journal Article, 2021, DOI
• Bronagh Gallagher, Meabh Foley, Claire M. Slattery, Gabriele Gusciute, Enda Shanahan, Declan M. McLoughlin, Ketamine as an adjunctive therapy for major depression - a randomised controlled pragmatic pilot trial (Karma-Dep Trial), HRB Open Research, 3, 2020, p90Journal Article, 2020, DOI
• Short B, Dong V, Gálvez V, Vulovic V, Martin D, Bayes AJ, Zarate CA, Murrough JW, McLoughlin DM, Riva-Posse P, Schoevers R, Fraguas R, Glue P, Fam J, McShane R, Loo CK., Development of the Ketamine Side Effect Tool (KSET)., Journal of affective disorders, 266, 2020, p615-620Journal Article, 2020, DOI
• Alexander L, Kelly L, Doody E, Brady S, Roddy D, Counihan E, Delaney L, McLoughlin D, Malone K., Over the Cuckoo's Nest: Does Experiencing Electroconvulsive Therapy Change Your Mind? A Mixed Methods Study of Attitudes and Impact of Electroconvulsive Therapy on Patients and Their Relatives., The journal of ECT, 36, (3), 2020, p172-179Journal Article, 2020, DOI
• Colbert SA, McCarron S, Ryan G, McLoughlin DM., Immediate Impact of Coronavirus Disease 2019 on Electroconvulsive Therapy Practice., The journal of ECT, 36, (2), 2020, p86-87Journal Article, 2020, DOI
• McGrory CL, Ryan KM, Gallagher B, McLoughlin DM., Vascular endothelial growth factor and pigment epithelial-derived factor in the peripheral response to ketamine., Journal of affective disorders, 273, 2020, p380-383Journal Article, 2020, DOI
• Brady C, Fenton C Loughran O, Higgins A, McLoughlin D, Nursing home staff mental health during the Covid-19 pandemic in the Republic of Ireland, International Journal of Geriatric Psychiatry, 37, (1), 2021Journal Article, 2021, DOI
• Meechan CF, Laws KR, Young AH, McLoughlin DM, Jauhar S., A critique of narrative reviews of the evidence-base for ECT in depression., Epidemiology and psychiatric sciences, 31, 2022, pe10Journal Article, 2022, DOI
• Jelovac A, Kolshus E, McLoughlin DM., Relapse following bitemporal and high-dose right unilateral electroconvulsive therapy for major depression., Acta psychiatrica Scandinavica, 144, (3), 2021, p218-229Journal Article, 2021, DOI
• Gallagher B, Neiman A, Slattery MC, McLoughlin DM., Online news media reporting of ketamine as a treatment for depression from 2000 to 2017., Irish journal of psychological medicine, 2021, p1-9Journal Article, 2021, DOI
• Ryan KM, Finnegan M, Harkin A, McLoughlin DM., PBMC telomerase activity in depression and the response to electroconvulsive therapy., European archives of psychiatry and clinical neuroscience, 271, (7), 2021, p1297-1307Journal Article, 2021, DOI
• Bauer M, Glenn T, Achtyes ED, Alda M, Agaoglu E, Alt"nba" K, Andreassen OA, Angelopoulos E, Ardau R, Vares EA, Aydin M, Ayhan Y, Baethge C, Bauer R, Baune BT, Balaban C, Becerra-Palars C, Behere AP, Behere PB, Belete H, Belete T, Belizario GO, Bellivier F, Belmaker RH, Benedetti F, Berk M, Bersudsky Y, Bicakci ", Birabwa-Oketcho H, Bjella TD, Brady C, Cabrera J, Cappucciati M, Castro AMP, Chen WL, Cheung EYW, Chiesa S, Crowe M, Cuomo A, Dallaspezia S, Del Zompo M, Desai P, Dodd S, Donix M, Etain B, Fagiolini A, Fellendorf FT, Ferensztajn-Rochowiak E, Fiedorowicz JG, Fountoulakis KN, Frye MA, Geoffroy PA, Gonzalez-Pinto A, Gottlieb JF, Grof P, Haarman BCM, Harima H, Hasse-Sousa M, Henry C, Høffding L, Houenou J, Imbesi M, Isometsä ET, Ivkovic M, Janno S, Johnsen S, Kapczinski F, Karakatsoulis GN, Kardell M, Kessing LV, Kim SJ, König B, Kot TL, Koval M, Kunz M, Lafer B, Landén M, Larsen ER, Lenger M, Lewitzka U, Licht RW, Lopez-Jaramillo C, MacKenzie A, Madsen HØ, Madsen SAKA, Mahadevan J, Mahardika A, Manchia M, Marsh W, Martinez-Cengotitabengoa M, Martiny K, Mashima Y, McLoughlin DM, Meesters Y, Melle I, Meza-Urzúa F, Ming MY, Monteith S, Moorthy M, Morken G, Mosca E, Mozzhegorov AA, Munoz R, Mythri SV, Nacef F, Nadella RK, Nakanotani T, Nielsen RE, O'Donovan C, Omrani A, Osher Y, Ouali U, Pantovic-Stefanovic M, Pariwatcharakul P, Petite J, Pfennig A, Ruiz YP, Pilhatsch M, Pinna M, Pompili M, Porter R, Quiroz D, Rabelo-da-Ponte FD, Ramesar R, Rasgon N, Ratta-Apha W, Ratzenhofer M, Redahan M, Reddy MS, Reif A, Reininghaus EZ, Richards JG, Ritter P, Rybakowski JK, Sathyaputri L, Scippa ÂM, Simhandl C, Severus E, Smith D, Smith J, Stackhouse PW, Stein DJ, Stilwell K, Strejilevich S, Su KP, Subramaniam M, Sulaiman AH, Suominen K, Tanra AJ, Tatebayashi Y, Teh WL, Tondo L, Torrent C, Tuinstra D, Uchida T, Vaaler AE, Veeh J, Vieta E, Viswanath B, Yoldi-Negrete M, Yalcinkaya OK, Young AH, Zgueb Y, Whybrow PC., Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder., International journal of bipolar disorders, 9, (1), 2021, p26Journal Article, 2021, DOI
• Rimmerman N, Verdiger H, Goldenberg H, Naggan L, Robinson E, Kozela E, Gelb S, Reshef R, Ryan KM, Ayoun L, Refaeli R, Ashkenazi E, Schottlender N, Ben Hemo-Cohen L, Pienica C, Aharonian M, Dinur E, Lazar K, McLoughlin DM, Zvi AB, Yirmiya R., Microglia and their LAG3 checkpoint underlie the antidepressant and neurogenesis-enhancing effects of electroconvulsive stimulation., Molecular psychiatry, 2021Journal Article, 2021, DOI
• Loughran O, Finnegan M, Dud I, Galligan T, Kennedy M, McLoughlin DM., Decision-making Capacity for Treatment After Electroconvulsive Therapy for Depression., The journal of ECT, 2021Journal Article, 2021, DOI
• Fenton C, McLoughlin DM., Usefulness of Hamilton rating scale for depression subset scales and full versions for electroconvulsive therapy., PloS one, 16, (11), 2021, pe0259861Journal Article, 2021, DOI
• Luykx JJ, Loef D, Lin B, van Diermen L, Nuninga JO, van Exel E, Oudega ML, Rhebergen D, Schouws SNTM, van Eijndhoven P, Verwijk E, Schrijvers D, Birkenhager TK, Ryan KM, Arts B, van Bronswijk SC, Kenis G, Schurgers G, Baune BT, Arns M, van Dellen EE, Somers M, Sommer IEC, Boks MP, Gülöksüz S, McLoughlin DM, Dols A, Rutten BPF., Interrogating Associations Between Polygenic Liabilities and Electroconvulsive Therapy Effectiveness., Biological psychiatry, 2021Journal Article, 2021, DOI
• Kirov G, Jauhar S, Sienaert P, Kellner CH, McLoughlin DM., Electroconvulsive therapy for depression: 80 years of progress., The British journal of psychiatry : the journal of mental science, 219, (5), 2021, p594-597Journal Article, 2021, DOI
• Doody MRCPsych, Eimear, Ryan, Karen M., O'Toole MRCPsych, Clare, McLoughlin, Declan M., Telomere length in patients with anorexia nervosa, Psychiatry Research Communications, 2, (1), 2022, p100022Journal Article, 2022, DOI
• Alexander, Lauren, Kelly, Louisa, Doody, Eimear, Brady, Shane, Roddy, Darren, Counihan, Eimear, Delaney, Liam, McLoughlin, Declan, Malone, Kevin, Over the Cuckoo"s Nest, The Journal of ECT, 36, (3), 2020, p172-179Journal Article, 2020, DOI
• Yates, DM, Manser, C, De Vos, KJ, Shaw, CE, McLoughlin, DM, Miller, CC, Neurofilament subunit (NFL) head domain phosphorylation regulates axonal transport of neurofilaments., European Journal of Cell Biology, 88, (4), 2009, p193 - 202Journal Article, 2009, DOI , URL
• Lau, KF, Chan, WM, Perkinton, MS, Tudor, EL, Chang, RC, Chan, HY, McLoughlin, DM, Miller, CC, Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription., The Journal of Biological Chemistry, 283, (50), 2008, p34728 - 34737Journal Article, 2008, DOI , TARA - Full Text
• Manser, C, Stevenson, A, Banner, S, Davies, J, Tudor, EL, Ono, Y, Leigh, PN, McLoughlin, DM, Shaw, CE, Miller, CC, Deregulation of PKN1 activity disrupts neurofilament organisation and axonal transport., FEBS Letters, 582, (15), 2008, p2303 - 2308Journal Article, 2008, DOI
• Eranti, SV, Mogg, AJ, Pluck, GC, Landau, S, McLoughlin, DM, Methohexitone, propofol and etomidate in electroconvulsive therapy for depression: a naturalistic comparison study., Journal of Affective Disorders, 113, (1-2), 2009, p165 - 171Journal Article, 2009, DOI
• Knapp, M, Romeo, R, Mogg, A, Eranti, S, Pluck, G, Purvis, R, Brown, RG, Howard, R, Philpot, M, Rothwell, J, Edwards, D, McLoughlin, DM, Cost-effectiveness of transcranial magnetic stimulation vs. electroconvulsive therapy for severe depression: a multi-centre randomised controlled trial., Journal of Affective Disorders, 109, (3), 2008, p273 - 285Journal Article, 2008, DOI
• Mogg, A, Pluck, G, Eranti, SV, Landau, S, Purvis, R, Brown, RG, Curtis, V, Howard, R, Philpot, M, McLoughlin, DM, A randomized controlled trial with 4-month follow-up of adjunctive repetitive transcranial magnetic stimulation of the left prefrontal cortex for depression., Psychological Medicine, 38, (3), 2008, p323 - 333Journal Article, 2008, DOI
• McLoughlin, DM, Miller, CC, The FE65 proteins and Alzheimer's disease., Journal of Neuroscience Research, 86, (4), 2008, p744 - 754Journal Article, 2008, DOI
• De Vos, KJ, Chapman, AL, Tennant, ME, Manser, C, Tudor, EL, Lau, KF, Brownlees, J, Ackerley, S, Shaw, PJ, McLoughlin, DM, Shaw, CE, Leigh, PN, Miller, CC, Grierson, AJ, Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content., Human Molecular Genetics, 16, (22), 2007, p2720 - 2728Journal Article, 2007, DOI
• McLoughlin, DM, Mogg, A, Eranti, S, Pluck, G, Purvis, R, Edwards, D, Landau, S, Brown, R, Rabe-Heskith, S, Howard, R, Philpot, M, Rothwell, J, Romeo, R, Knapp, M, The clinical effectiveness and cost of repetitive transcranial magnetic stimulation versus electroconvulsive therapy in severe depression: a multicentre pragmatic randomised controlled trial and economic analysis., Health Technology Assessment (Winchester, England), 11, (24), 2007, p1 - 54Journal Article, 2007, URL
• Mogg, A, Purvis, R, Eranti, S, Contell, F, Taylor, JP, Nicholson, T, Brown, RG, McLoughlin, DM, Repetitive transcranial magnetic stimulation for negative symptoms of schizophrenia: a randomized controlled pilot study., Schizophrenia Research, 93, (1-3), 2007, p221 - 228Journal Article, 2007, DOI
• Rogelj, B, Mitchell, JC, Miller, CC, McLoughlin, DM, The X11/Mint family of adaptor proteins., Brain Research Reviews, 52, (2), 2006, p305 - 315Journal Article, 2006, DOI
• Miller, CC, McLoughlin, DM, Lau, KF, Tennant, ME, Rogelj, B, The X11 proteins, Abeta production and Alzheimer's disease., Trends in Neurosciences, 29, (5), 2006, p280 - 285Journal Article, 2006, DOI
• Uher, R, Yoganathan, D, Mogg, A, Eranti, SV, Treasure, J, Campbell, IC, McLoughlin, DM, Schmidt, U, Effect of left prefrontal repetitive transcranial magnetic stimulation on food craving., Biological Psychiatry, 58, (10), 2005, p840 - 842Journal Article, 2005, DOI
• Tudor, EL, Perkinton, MS, Schmidt, A, Ackerley, S, Brownlees, J, Jacobsen, NJ, Byers, HL, Ward, M, Hall, A, Leigh, PN, Shaw, CE, McLoughlin, DM, Miller, CC, ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth., The Journal of Biological Chemistry, 280, (41), 2005, p34735 - 34740Journal Article, 2005, DOI , TARA - Full Text
• Perkinton, MS, Standen, CL, Lau, KF, Kesavapany, S, Byers, HL, Ward, M, McLoughlin, DM, Miller, CC, The c-Abl tyrosine kinase phosphorylates the Fe65 adaptor protein to stimulate Fe65/amyloid precursor protein nuclear signaling., The Journal of Biological Chemistry, 279, (21), 2004, p22084 - 22091Journal Article, 2004, DOI , TARA - Full Text
• Lee, JH, Lau, KF, Perkinton, MS, Standen, CL, Shemilt, SJ, Mercken, L, Cooper, JD, McLoughlin, DM, Miller, CC, The neuronal adaptor protein X11alpha reduces Abeta levels in the brains of Alzheimer's APPswe Tg2576 transgenic mice., The Journal of Biological Chemistry, 278, (47), 2003, p47025 - 47029Journal Article, 2003, DOI , TARA - Full Text
• Kesavapany, S, Lau, KF, Ackerley, S, Banner, SJ, Shemilt, SJ, Cooper, JD, Leigh, PN, Shaw, CE, McLoughlin, DM, Miller, CC, Identification of a novel, membrane-associated neuronal kinase, cyclin-dependent kinase 5/p35-regulated kinase., The Journal of Neuroscience, 23, (12), 2003, p4975 - 4983Journal Article, 2003, TARA - Full Text
• Kesavapany, S, Banner, SJ, Lau, KF, Shaw, CE, Miller, CC, Cooper, JD, McLoughlin, DM, Expression of the Fe65 adapter protein in adult and developing mouse brain., Neuroscience, 115, (3), 2002, p951 - 960Journal Article, 2002, DOI
• Lau, KF, Howlett, DR, Kesavapany, S, Standen, CL, Dingwall, C, McLoughlin, DM, Miller, CC, Cyclin-dependent kinase-5/p35 phosphorylates Presenilin 1 to regulate carboxy-terminal fragment stability., Molecular and Cellular Neurosciences, 20, (1), 2002, p13 - 20Journal Article, 2002, DOI
• Lovestone, S, McLoughlin, DM, Protein aggregates and dementia: is there a common toxicity?, Journal of Neurology, Neurosurgery, and Psychiatry, 72, (2), 2002, p152 - 161Journal Article, 2002
• Lyons, D, McLoughlin, DM, Recent advances: Psychiatry., BMJ (Clinical research ed.), 323, (7323), 2001, p1228 - 1231Journal Article, 2001
• Standen, CL, Brownlees, J, Grierson, AJ, Kesavapany, S, Lau, KF, McLoughlin, DM, Miller, CC, Phosphorylation of thr(668) in the cytoplasmic domain of the Alzheimer's disease amyloid precursor protein by stress-activated protein kinase 1b (Jun N-terminal kinase-3)., Journal of Neurochemistry, 76, (1), 2001, p316 - 320Journal Article, 2001, DOI
• McLoughlin, DM, Standen, CL, Lau, KF, Ackerley, S, Bartnikas, TP, Gitlin, JD, Miller, CC, The neuronal adaptor protein X11alpha interacts with the copper chaperone for SOD1 and regulates SOD1 activity., The Journal of Biological Chemistry, 276, (12), 2001, p9303 - 9307Journal Article, 2001, DOI , URL , TARA - Full Text
• Eranti SV, McLoughlin DM, Electroconvulsive therapy - state of the art, British Journal of Psychiaty, 182, 2003, p8 - 9Journal Article, 2003, TARA - Full Text
• Semkovska M, McLoughlin DM , Cognitive effects of electroconvulsive therapy for depression: a systematic review and meta-analysis., Biological Psychiatry, 2010Journal Article, 2010
• Nicholson TRJ, Pariante C, McLoughlin D, Stendhal syndrome: a case of cultural overload., BMJ Case Reports, 2009Journal Article, 2009, DOI
• Stevenson A, Yates DM, Manser C, De Vos KJ, Vagnoni A, Leigh PN, McLoughlin DM, Miller CCJ, Riluzole protects against glutamate-induced slowing of neurofilament axonal transport. , Neuroscience Letters, 454, (2), 2009, p161-164Journal Article, 2009, DOI
• Hotopf M, Laird B, Singh I, Churchill R, David AS, McLoughlin DM, Richardson G, Szmukler G, Capacity, consent and electroconvulsive therapy: A qualitative and cross-sectional study, Journal of Mental Health, 17, (3), 2008, p315-325Journal Article, 2008, DOI
• Eranti S, Mogg A, Pluck G, Landau S, Purvis R, Brown RG, Howard R, Knapp M, Philpot M, Rabe-Hesketh S, Romeo R, Rothwell J, Edwards D, McLoughlin DM, A Randomized, Controlled Trial With 6-Month Follow-Up of Repetitive Transcranial Magnetic Stimulation and Electroconvulsive Therapy for Severe Depression , American Journal of Psychiatry, 164, 2007, p73-81Journal Article, 2007, DOI , TARA - Full Text
• Lee J-H, Lau K-F, Perkinton MS, Standen CL, Rogelj B, Falinska A, McLoughlin DM, Miller CCJ, The Neuronal Adaptor Protein X11beta Reduces Amyloid beta-Protein Levels and Amyloid Plaque Formation in the Brains of Transgenic Mice*, Journal of Biological Chemistry, 279, 2004, p49099-49104Journal Article, 2004, DOI , TARA - Full Text
• Kesavapany S, Lau K-F, McLoughlin DM, Brownlees J, Ackerley S, Leigh NP, Shaw CE, Miller CCJ, p35/cdk5 binds and phosphorylates β-catenin and regulates β-catenin/presenilin-1 interaction, European Journal of Neuroscience, 13, (2), 2001, p241-247Journal Article, 2001, DOI
• Lau K-F, McLoughlin DM, Standen C, Irving NG, Miller CCJ, Fe65 and X11beta co-localise with and compete for binding to the amyloid precursor protein. , Neuroreport, 11, (16), 2000, p3607-3610Journal Article, 2000, URL
• Lau K-F, McLoughlin DM, Standen C, Miller CCJ, X11α and X11β Interact with Presenilin-1 via Their PDZ Domains , Molecular Cell Neuroscience, 16, (5), 2000, p555-563Journal Article, 2000, DOI
• McLoughlin DM, Irving NG, Brownlees J, Brion J-P, Leroy K, Miller CCJ, Mint2/X11-like co-localises with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease., European Journal of Neuroscience, 11, (6), 1999, p1988-1994Journal Article, 1999, DOI
• Morton J, McLoughlin DM, Whiting S, Russell GFM, Carnitine levels in patients with skeletal myopathy due to anorexia nervosa before and after refeeding., International Journal of Eating Disorders, 26, 1999, p341-344Journal Article, 1999, URL
• Guidato S, McLoughlin DM, Grierson A, Miller CCJ., Cyclin D2 interacts with cdk-5 and modulates cellular cdk-5/p35 activity., Journal of Neurochemistry, 70, (1), 1998, p335-340Journal Article, 1998, DOI
• Blanco G, Brown SDM, Irving N, Miller CCJ, McLoughlin DM. , Mapping of the human and murine X11-like genes, the murine Fe65 gene and the human Fe65-like gene: genes encoding for phosphotyrosine binding domain proteins that interact with the Alzheimer's disease amyloid precursor protein., Mammalian Genome, 9, (6), 1998, p473-475Journal Article, 1998, DOI
• Mitchell JC, Ariff BB, Yates DM, Lau KF, Perkinton MS, Rogelj B, Stephenson JD, Miller CC, McLoughlin DM., X11beta rescues memory and long-term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice., Human Molecular Genetics, 18, (23), 2009, p4492-4500Journal Article, 2009, DOI , URL , TARA - Full Text
• McLoughlin DM, Spargo T, Wassif W, Newham D, Peters TJ, Lantos P, Russell GFM, Structural and functional changes in skeletal muscle in anorexia nervosa., Acta Neuropathologica, 95, (6), 1998, p632-640Journal Article, 1998, DOI
• McLoughlin DM, Miller CCJ. , The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosisine-binding domain proteins in the yeast two-hybrid system. , FEBS Letters, 397, (2-3), 1996, p197-200Journal Article, 1996, DOI
• Holmes C, Levy R, McLoughlin DM, Powell JF, Lovestone S. , Apolipoprotein E: non-cognitive symptoms and cognitive decline in late onset Alzheimer's disease., Journal of Neurology, Neurosurgery, and Psychiatry , 61, 1996, p580-583Journal Article, 1996, DOI
• McLoughlin DM, Cooney C, Holmes C, Levy R. , Carer informants for dementia sufferers: carer awareness of cognitive impairment in an elderly-community resident sample., Age and Ageing, 25, (5), 1996, p367-371Journal Article, 1996, URL
• Richards M, McLoughlin D, Levy R. , The relationship between extrapyramidal signs and cognitive function in patients with moderate to severe Alzheimer's disease., International Journal of Geriatric Psychiatry, 10, (5), 1995, p395-399Journal Article, 1995, DOI
• McLoughlin D, Lucey J, Dinan T., Central serotonergic hyperresponsivity in late-onset Alzheimer's disease. , American Journal of Psychiatry, 151, (11), 1994, p1701-1703Journal Article, 1994, URL
• O'Keane V, McLoughlin D, Dinan T. , D-fenfluramine-induced prolactin and cortisol release in major depression: response to treatment., Journal of Affective Disorders, 26, (3), 1992, p143-150.Journal Article, 1992, DOI
• Farren C, McLoughlin D, Clare A. , Procedures for involuntary admission to public and private psychiatric facilities. , Irish Journal of Psychological Medicine, 9, (2), 1992, p96-100Journal Article, 1992
• McLoughlin D, McKeon P., Bipolar disorder and cerebral sarcoidosis., British Journal of Psychiatry, 158, 1991, p410-413Journal Article, 1991, URL
• McLoughlin DM, Review: high frequency repetitive transcranial magnetic stimulation improves symptoms of major depression. , Evidence Based Mental Health., 12, (3), 2009, p80-81Journal Article, 2009, DOI
• Transcranial magnetic stimulation. in, editor(s)Gelder M, Andrreasen, Lopez-Ibor J, Geddes J , New Oxford Textbook of Psychiatry, Oxford University Press, 2009, [McLoughlin D, Mogg A]Book Chapter, 2009
• Dunne R, Kavanagh A, McLoughlin DM, Electroconvulsive therapy, capacity and the law in Ireland., Irish Journal of Psychological Medicine, 26, 2009, p3-5Journal Article, 2009, URL , TARA - Full Text
• Dunne R, McLoughlin DM, Physical treatments., Medicine, 36, (9), 2008, p499-500Journal Article, 2008, DOI
• McLoughlin DM, Vagus rules still apply., Psychological Medicine, 38, 2008, p625-627Journal Article, 2008, DOI
• Yates D, McLoughlin DM, The molecular pathology of Alzheimer's disease, Psychiatry, 7, (1), 2008, p1-5Journal Article, 2008, DOI
• Kelly BD, McLoughlin DM, Physician-assisted suicide and psychiatry, Psychiatry, 5, (8), 2006, p289-291Journal Article, 2006, DOI
• Kelly, B.D., McLoughlin, D.M., Physician-assisted suicide and psychiatry, Psychiatry, 8, (7), 2009, p276-279Journal Article, 2009, DOI , URL
• Mineur YS, McLoughlin D, Crusio WE, Sluyter F, Genetic mouse models of Alzheimer's disease., Neural Plast, 12, (4), 2005, p299-310Journal Article, 2005, DOI , TARA - Full Text
• Is ECT given in bipolar disorder and does TMS offer more? in, editor(s)McDonald C, Schulz K, Murray RM, Tohen M , Bipolar Disorder: The Upswing in Research and Treatment., London, Parthenon Publishing, 2005, [Mogg A, Erranti S, Pluck G, McLoughlin DM. ]Book Chapter, 2005
• McLoughlin DM, Irving NG, Miller CCJ, The Fe65 and X11 families of proteins: proteins that interact with the Alzheimer's disease amyloid precursor protein., Biochemical Society Transactions, 26, 1998, p497-500Journal Article, 1998
• Dementia: Basic Neurosciences. in, editor(s)Brocklehurst J, Tallis R, Flint H , Brocklehurst's Textbook of Geriatric Medicine & Gerontology, Edinburgh, Churchill Livingstone, 1998, [Carter J, McLoughlin DM.]Book Chapter, 1998
• Physical disorders and psychiatric illness. in, editor(s)Wheatley D, Smith D , Psychopharmacology of Cognitive and Psychiatric Disorders in the Elderly., London, Chapman & Hall, 1998, [Krasucki C, McLoughlin DM.]Book Chapter, 1998
• Substance misuse in the elderly in, Norman IJ, Redfern SJ , Mental Health Care for Elderly People. , London, Churchill Livingstone, 1997, [McLoughlin DM, Farrell M.]Book Chapter, 1997
• McLoughlin D, Levy R., The differential diagnosis of dementia. , Acta Neurologica Scandinavica, S165, 1996, p92-100Journal Article, 1996
• McLoughlin D, Lovestone S., Alzheimer's disease: recent advances in molecular pathology and genetics., International Journal of Geriatric Psychiatry, 9, (6), 1994, p431-444Journal Article, 1994, DOI
• McLoughlin DM , Repetitive Transcranial Magnetic Stimulation Versus Electroconvulsive Therapy: Efficacy of Treatment in Nonpsychotic Patients With Depression , 2007, - 1118-1119.Miscellaneous, 2007, DOI
• Eranti SV, McLoughlin DM. , Changing use of ECT, 2003, - 173Miscellaneous, 2003, URL
• Holmes C, McLoughlin D, Powell J, Lovestone S., Apolipoprotein E: non-cognitive symptoms and cognitive decline in late onset Alzheimer's disease, 1997, - 274Miscellaneous, 1997, DOI
• McLoughlin D, Natural Born Killers, 1995, - 499-500Miscellaneous, 1995
• McLoughlin D., A Palpable Hit (review of the movie "Trainspotting") , 1996, - 585Miscellaneous, 1996, URL
• McLoughlin D, Realism about mental illness (review of the television documentary series "Minders")., 1995, - 1205Miscellaneous, 1995, URL
• McLoughlin D, Carter J., Conference Report: The Fourth International Conference on Alzheimer's Disease and Related Disorders, International Journal of Geriatric Psychiatry, 9, 1994, pp1003-1004Conference Paper, 1994
• McLoughlin D, Priest R., Halcyon days over for our favourite hypnotic, 1991, - 13Miscellaneous, 1991
• McLoughlin D, Priest R., Life after Halcion: what are the remaining options?, 1991, - 13-15Miscellaneous, 1991
• McLoughlin DM, Review: repetitive transcranial magnetic stimulation is of unknown effectiveness in people with depression., Evidence Based Mental Health, 6, (4), 2003, p118Journal Article, 2003, DOI , TARA - Full Text
• Kelly, B.D., McLoughlin, D.M., Euthanasia, assisted suicide and psychiatry: a Pandora's box, Journal of Psychiatry, 181, (4), 2002, p278-279Journal Article, 2002, DOI , URL , TARA - Full Text
• Tudor EL, Galtrey CM, Perkinton MS, Lau KF, De Vos KJ, Mitchell JC, Ackerley S, Hortobágyi T, Vámos E, Leigh PN, Klasen C, McLoughlin DM, Shaw CE, Miller CC, Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology., Neuroscience, 167, (3), 2010, p774-785Journal Article, 2010, DOI , TARA - Full Text
• Yu HT, Chan WW, Chai KH, Lee CW, Chang RC, Yu MS, McLoughlin DM, Miller CC, Lau KF, Transcriptional regulation of human FE65, a ligand of Alzheimer's disease amyloid precursor protein, by Sp1., Journal of Cellular Biochemistry, 109, (4), 2010, p782-93Journal Article, 2010, DOI
• Jacqueline C. Mitchell, Michael S. Perkinton, Darran M. Yates, Kwok-Fai Lau, Boris Rogelj, Christopher C.J. Miller, Declan M. McLoughlin, Expression of the Neuronal Adaptor Protein X11alpha Protects Against Memory Dysfunction in a Transgenic Mouse Model of Alzheimer's Disease, Journal of Alzheimer's Disease, 20, (1), 2010, p31-36Journal Article, 2010, DOI , URL , TARA - Full Text
• Tracy DK, O'Daly O, Joyce DW, Michalopoulou PG, Basit BB, Dhillon G, McLoughlin DM, Shergill SS, An evoked auditory response fMRI study of the effects of rTMS on putative AVH pathways in healthy volunteers., Neuropsychologia, 48, (1), 2010, p270-7Journal Article, 2010, DOI
• Lau KF, Perkinton MS, Rodriguez L, McLoughlin DM, Miller CC, An X11[alpha]/FSBP complex represses transcription of the GSK3[beta] gene promoter., NeuroReport, 21, (11), 2010, p1-6Journal Article, 2010, DOI , URL , TARA - Full Text
• Maria Semkovska, Deborah Keane, Oyemi Babalola, Declan M. McLoughlin, Unilateral brief-pulse electroconvulsive therapy and cognition: Effects of electrode placement, stimulus dosage and time, Journal of Psychiatric Research, 45, (6), 2011, p770-780Journal Article, 2011, DOI , URL
• Semkovska M, McLoughlin DM, Objective cognitive performance associated with electroconvulsive therapy for depression: a systematic review and meta-analysis., Biological psychiatry, 68, (6), 2010, p568-77Journal Article, 2010, DOI , URL
• Ross A. Dunne, Declan M. McLoughlin, Regional Variation in Electroconvulsive Therapy Use, Irish Medical Journal, 104, (3), 2011, p84 - 87Journal Article, 2011, URL , TARA - Full Text
• Agyapong V.I.O., Farren C.K. and McLoughlin D, Mobile phone text message interventions in psychiatry- what are the possibilities?, Current Psychiatry Reviews, 7, (1), 2011, p1 - 7Journal Article, 2011, DOI
• Sinead O'Donovan, Mark Kennedy, Blaithin Guinan, Shane O'Mara, Declan M. McLoughlin, A comparison of brief pulse and ultrabrief pulse electroconvulsive stimulation on rodent brain and behaviour, Progress in Neuropsychopharmacology & Biological Psychiatry, 37, (1), 2012, p147-52Journal Article, 2012, DOI , URL , TARA - Full Text
• Hao Y, Chai KH, McLoughlin DM, Chan HY, Lau KF, Promoter characterization and genomic organization of the human X11ß gene APBA2., Neuroreport, 23, (3), 2012, p146-51Journal Article, 2012, DOI , URL
• Manser C, Guillot F, Vagnoni A, Davies J, Lau KF, McLoughlin DM, De Vos KJ, Miller CC, Lemur tyrosine kinase-2 signalling regulates kinesin-1 light chain-2 phosphorylation and binding of Smad2 cargo., Oncogene, 2011Journal Article, 2011, DOI , URL
• Dunne RA, McLoughlin DM, Systematic review and meta-analysis of bifrontal electroconvulsive therapy versus bilateral and unilateral electroconvulsive therapy in depression., The World Journal of Biological Psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 13, (4), 2012, p248-258Review Article, 2012, DOI , URL
• Wassif, WS, McLoughlin, DM, Vincent, RP, Conroy, S, Russell, GFM, Taylor, NF, Steroid metabolism and excretion in severe anorexia nervosa: effects of refeeding, AMERICAN JOURNAL OF CLINICAL NUTRITION, 93, 2011Journal Article, 2011
• Agyapong VI, Milnes J, McLoughlin DM, Farren CK, Perception of patients with alcohol use disorder and comorbid depression about the usefulness of supportive text messages., Technology and health care : official journal of the European Society for Engineering and Medicine, 21, (1), 2013, p31-39Journal Article, 2013, DOI
• Semkovska M, McLoughlin DM, Measuring Retrograde Autobiographical Amnesia Following Electroconvulsive Therapy: Historical Perspective and Current Issues., The journal of ECT, 29, (2), 2013, p127-133Journal Article, 2013, DOI
• Agyapong VI, Ahern S, McLoughlin DM, Farren CK, Supportive text messaging for depression and comorbid alcohol use disorder: single-blind randomised trial., Journal of affective disorders, 141, (2-3), 2012, p168-76Journal Article, 2012, DOI
• Hughes MM, Carballedo A, McLoughlin DM, Amico F, Harkin A, Frodl T, Connor TJ, Tryptophan depletion in depressed patients occurs independent of kynurenine pathway activation., Brain, behavior, and immunity, 26, (6), 2012, p979-987Journal Article, 2012, DOI
• Agyapong VI, McLoughlin D, Promoting psychiatry as a career option for Ghanaian medical students through a public-speaking competition., Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry, 36, (3), 2012, p229-32Journal Article, 2012, DOI
• Semkovska M, Noone M, Carton M, McLoughlin DM, Measuring consistency of autobiographical memory recall in depression., Psychiatry research, 197, (1-2), 2012, p41-8Journal Article, 2012, DOI
• O'Donovan S, Kennedy M, Guinan B, O'Mara S, McLoughlin DM, A comparison of brief pulse and ultrabrief pulse electroconvulsive stimulation on rodent brain and behaviour., Progress in neuro-psychopharmacology & biological psychiatry, 37, (1), 2012, p147-52Journal Article, 2012, DOI
• Frodl T, Carballedo A, Hughes MM, Saleh K, Fagan A, Skokauskas N, McLoughlin DM, Meaney J, O'Keane V, Connor TJ, Reduced expression of glucocorticoid-inducible genes GILZ and SGK-1: high IL-6 levels are associated with reduced hippocampal volumes in major depressive disorder., Translational psychiatry, 2, 2012, pe88Journal Article, 2012, DOI
• Chai KH, McLoughlin DM, Chan TF, Chan HY, Lau KF, Genomic organization and promoter cloning of the human X11" gene APBA1., DNA and cell biology, 31, (5), 2012, p651-9Journal Article, 2012, DOI
• Eranti SV, Thirthalli J, Pattan V, Mogg A, Pluck G, Velayudhan L, Chan J, Gangadhar BN, McLoughlin DM, Comparison of electroconvulsive therapy practice between London and Bengaluru., The journal of ECT, 27, (4), 2011, p275-80Journal Article, 2011
• Dunne R, McLoughlin DM, Regional variation in electroconvulsive therapy use., Irish medical journal, 104, (3), 2011, p84-7Journal Article, 2011
• Semkovska M, Keane D, Babalola O, McLoughlin DM, Unilateral brief-pulse electroconvulsive therapy and cognition: effects of electrode placement, stimulus dosage and time., Journal of psychiatric research, 45, (6), 2011, p770-80Journal Article, 2011
• Practical administration of ECT in, editor(s)A. Easton , The ECT Handbook., London, Royal College of Psychiatrists, 2013, [Dunne, R., McLoughlin, D.M.]Book Chapter, 2013
• Electroconvulsive therapy, brain stimulation and neurosurgery for mental illness in, editor(s)P. Wright , Core Psychiatry, London, Elsevier, 2012, [Dunne, R., McLoughlin, D.M.]Book Chapter, 2012
• Agyapong V.I.O., Singh K., Savage M., Thekiso B.T., Finn M, Farren C.K. McLoughlin D.M., Use of codeine-containing medicines by Irish psychiatric in-patients before and after regulatory limitations on their supply. , Irish Journal of Psychological Medicine, 30, (01), 2013, p7 - 12Journal Article, 2013, DOI , TARA - Full Text
• Kolshus E, Dalton VS, Ryan KM, McLoughlin DM, When less is more - microRNAs and psychiatric disorders., Acta psychiatrica Scandinavica, 129, (4), 2014, p241 - 256Journal Article, 2014, DOI
• Dalton, VS, Kolshus, E, McLoughlin, DM, Epigenetics and depression: return of the repressed, Journal of Affective Disorders , 155, (1), 2014, p1-12Journal Article, 2014, DOI , TARA - Full Text
• Thekiso, T.B., Heron, E.A., Masood, B., Murphy, M., McLoughlin, D.M., Kennedy, N., Mauling of the "celtic Tiger": Clinical characteristics and outcome of first-episode depression secondary to the economic recession in Ireland, Journal of Affective Disorders, 151, (2), 2013, p455-460Journal Article, 2013, DOI
• Jelovac, A., Kolshus, E., McLoughlin, D.M., Relapse following successful electroconvulsive therapy for major depression: A meta-analysis, Neuropsychopharmacology, 38, (12), 2013, p2467-2474Journal Article, 2013, DOI , TARA - Full Text
• Agyapong, V.I.O., McLoughlin, D.M., Farren, C.K., Six-months outcomes of a randomised trial of supportive text messaging for depression and comorbid alcohol use disorder, Journal of Affective Disorders, 151, (1), 2013, p100-104Journal Article, 2013, DOI
• Ryan, K.M., O'Donovan, S.M., McLoughlin, D.M., Electroconvulsive stimulation alters levels of BDNF-associated microRNAs, Neuroscience Letters , 549, 2013, p125-129Journal Article, 2013, DOI
• Skelly N, Schnittger RI, Butterly L, Frorath C, Morgan C, McLoughlin DM, Fearon P, Quality of care in psychosis and bipolar disorder from the service user perspective., Qualitative health research, 23, (12), 2013, p1672-85Journal Article, 2013, DOI
• Ryan KM, O'Donovan SM, McLoughlin DM, Electroconvulsive stimulation alters levels of BDNF-associated microRNAs., Neuroscience letters, 549, 2013, p125-9Journal Article, 2013, DOI
• O'Donovan S*, Dalton VS*, Harkin A, McLoughlin DM; * joint first author, Effects of brief pulse and ultrabrief pulse electroconvulsive stimulation on rodent brain and behaviour in the corticosterone model of depression. , International Journal of Neuropsychopharmacology. DOI: 10.1017/S1461145714000500, 17, (9), 2014, p1477 - 1486Journal Article, 2014, DOI

• Semkovska M, McLoughlin DM , Retrograde autobiographical amnesia following ECT: on the difficulty of finding the baby and clearing murky bathwater, J ECT, 30, (3), 2014, p187 - 188Journal Article
• McLoughlin, DM, Vagus rules still apply., Psychological Medicine, 38, (5), 2008, p625 - 627Journal Article
• McLoughlin, DM, Review: repetitive transcranial magnetic stimulation is of unknown effectiveness in people with depression., Evidence-Based Mental Health, 6, (4), 2003, p118 - 118Journal Article
• Cigeroglu YB, McLoughlin D., Psychotherapy training in Turkey, 1994, - 650-651Miscellaneous, URL
• Lovestone S, McLoughlin D., Alzheimer's disease: molecular biology and the quest for a treatment. , Care of the Elderly, 6, 1994, p149-152Journal Article
• Dunne RA, McLoughlin DM, Physical treatments, Medicine , 40, 2012, p672 - 673Journal Article

I have been investigating the neuronal signalling function of the Alzheimer's disease amyloid precursor protein (APP) and was among the first to identify the FE65 and X11 adaptor proteins as APPbinding partners. To study their functions in vivo, we have made X11 transgenic mice and have demonstrated that the X11s regulate APP processing and reduce cerebral Ab production and deposition. The neuronal X11 proteins are therefore novel therapeutic targets for Alzheimer's disease. I am now leading a research group studying behavioural and electrophysiological effects of X11- mediated reduction in cerebral Ab in an Alzheimer's animal model. On the clinical side, I have also been leading randomised controlled trials of therapeutic neuromodulation techniques (e.g. transcranial magnetic stimulation, electroconvulsive therapy) for neuropsychiatric disorders such as depression and schizophrenia. In St Patrick's Hospital and TCD, we are about to start a 5-year research programme called the EFFECT-Dep Study (enhancing the effectiveness of electroconvulsive therapy in severe depression and understanding its molecular mechanism of action). This programme is supported by a HRB Translational Research Award and its purpose is to improve ECT practice and use it to interrogate the molecular neurobiology of depression. We will carry out a definitive randomised controlled trial comparing bilateral and high-dose unilateral ECT, recruiting 140 patients with severe depression. We will also use an animal model of ECT treatment to characterise changes in global protein expression (i.e. the proteome) in both brain and blood plasma and also carry out similar studies using plasma from depressed patients recruited into the clinical trial. The results of these studies will improve clinical ECT and also help us understand better the molecular mechanism of action of ECT, as well as antidepressant drugs, and lead to identification of candidate peripheral biomarkers for depression, treatment response and depression relapse.