Dr. Norita Gildea

Dr. Norita Gildea

Assistant Professor, Physiology


Biography

Dr Norita Gildea obtained her PhD in Exercise Physiology in 2017 from Trinity College Dublin. Her doctoral research was centered on exercise intolerance and microvascular dysfunction in individuals with type 2 diabetes. Her research interests extend to understanding the cellular mechanisms that influence macro- and microvascular function within prediabetes and ageing and the effect of different exercise training and lifestyle interventions on vascular and metabolic adaptations therein. Her work is focused on how personalised exercise prescription and other novel therapeutic interventions can improve both glycaemic and blood pressure control and reduce cardiovascular and cerebrovascular risk factors that are central to reducing the burden of prediabetes, and its progression to overt type 2 diabetes, in a plight for successful ageing.

Publications and Further Research Outputs

  • Gildea N, McDermott A, Rocha J, Crognale D, Nevin A, O'Shea D, Green S & Egaña M , Low-volume HIIT and MICT speed VO2 kinetics during high-intensity "work-to-work" cycling with a similar time-course in type 2 diabetes., J Appl Physiol, (133), 2022, p273 - 287Journal Article, 2022, TARA - Full Text
  • Green S, Kiely C, O'Connor E, Gildea N, O'Shea D & Egaña M, Differential effects of sex on adaptive responses of skeletal muscle vasodilation to exercise training in type 2 diabetes., J Diabetes Complications, (36), 2022Journal Article, 2022
  • Egaña M, Allen L, Gleeson K, Gildea N & Warmington S, Post-exercise cold water immersion does not improve subsequent 4-km cycling time-trial compared with passive and active recovery in normothermia, Front Sports Act Living, (25), 2021Journal Article, 2021
  • Gildea N, McDermott A, Rocha J, Green S, O'Shea D & Egaña M, Time-course of VO2 kinetics responses during moderate-intensity exercise subsequent to HIIT versus moderate-intensity continuous training in type 2 diabetes, J Appl Physiol , (130), 2021, p1646 - 1659Journal Article, 2021
  • Gildea N, McDermott A, Rocha J, O'Shea D, Green S & Egaña M., Time course of changes in VO2peak and O2 extraction during ramp cycle exercise following HIIT vs moderate-intensity continuous training in type 2 diabetes., Am J Physiol Regul Integr Comp Physiol, (320), 2021, p683 - 696Journal Article, 2021
  • Gildea N, Rocha J, O'Shea D, Green S & Egaña M., Priming exercise accelerates pulmonary oxygen uptake kinetics during "work-to-work" cycle exercise in middle-aged individuals with type 2 diabetes., Eur J Appl Physiol, (121), 2021, p409 - 423Journal Article, 2021
  • Green S, Kiely C, O'Connor E, Gildea N, O'Shea D & Egaña M., Effects of exercise training and sex on dynamic responses of O2 uptake in type 2 diabetes., Appl Physiol Nutr Metab, (45), 2020, p865 - 874Journal Article, 2020
  • Gildea N, Rocha J, McDermott A, O'Shea D, Green S & Egaña. , Influence of type 2 diabetes on muscle deoxygenation during ramp incremental cycle exercise in middle-aged individuals., Respir Physiol Neurobiol., (269), 2019Journal Article, 2019
  • Gildea N, McDermott A, Rocha J, Nevin A, O'Shea D, Green S & Egaña M, Influence of HIIT and MICT on the effects of "priming" exercise on oxygen uptake kinetics during moderate-intensity exercise in individuals with type 2 diabetes, Proc Physiol Soc., Europhysiology , Copenhagen, Denmark, September, 2022Conference Paper, 2022
  • Gildea N, McDermott A, Rocha J, Nevin A, O'Shea D, Green S & Egaña M., Time Course Adaptations in Oxygen Uptake and Muscle Deoxygenation Kinetics During Heavy-Intensity Exercise Initiated from an Elevated Baseline Subsequent to a 12 Week Low-Volume, High-Intensity Interval Training Intervention or Moderate-Intensity Continuous Training in Type 2 Diabetes, FASEB J, Experimental Biology, Orlando, USA, 2019, 33, (1), FASEB J, 2019Conference Paper, 2019
  • McDermott A, Nevin A, Gildea N, Rocha J, Crognale D, O'Shea D, Green S & Egaña M, Time course adaptations in cardiorespiratory fitness and fractional oxygen extraction with low-volume, high- intensity interval training and moderate-intensity continuous training in people with type 2 diabetes., Proc Physiol Soc, Europhysiology, London, UK, 2018, 41, Proc Physiol Soc, 2018Conference Paper, 2018
  • Nevin A, McDermott A, Gildea N, Rocha J, Crognale D, O'Shea D, Green S & Egaña M., he effects of low-volume high-intensity interval training on pulmonary oxygen uptake and muscle deoxygenation kinetics during heavy-intensity exercise in type 2 diabetes., Europhysiology, London, UK, 2018, (41), Proc Physiol Soc, 2018Conference Paper, 2018
  • Gildea N, McDermott A, Rocha J, Crognale D, Nevin A, O'Shea D, Green S & Egaña M., Time course adaptations in oxygen uptake and muscle deoxygenation kinetics during submaximal exercise subsequent to a 12 week moderate-intensity continuous training or low-volume, high-intensity interval training intervention in type 2 diabetes., Proc Physiol Soc, Europhysiology 2018, London, UK, 2018, 41, Proc Physiol Soc, 2018Conference Paper, 2018
  • Gildea N, Rocha J, Green S, O'Shea D & Egaña M, Influence of priming exercise on pulmonary oxygen uptake kinetics during heavy-intensity cycle exercise from an elevated baseline in type 2 diabetes., FASEB J, Experimental Biology , San Diego (USA), 2018, FASEB J, 2018Conference Paper, 2018
  • Rocha J, Gildea N, Green S, O'Shea D & Egaña M., Influence of priming exercise on pulmonary oxygen uptake and muscle deoxygenation kinetics during heavy-intensity cycle exercise in type 2 diabetes., Eur J Appl Physiol, 2016Journal Article, 2016
  • Gildea N, Rocha J, Corish O, Comerford J & Egaña M., The effects of the low recumbent body position in muscle deoxygenation during ramp incremental exercise, European College of Sports Sciences 2016, Vienna, Austria, 2016, 2016Conference Paper, 2016
  • Rocha J, Gildea N, Green S, O'Shea D & Egaña M., Influence of priming exercise and type 2 diabetes on VO2 and NIRS kinetics during submaximal exercise., Proc Physiol Soc , The Biomedical Basis of Elite Performance, London, UK, 2016, (35), 2016Conference Paper, 2016
  • Gildea N, Rocha J, Green S, O'Shea D & Egaña M., The effect of type 2 diabetes in muscle deoxygenation during ramp incremental cycling exercise, Proc Physiol Soc, The Biomedical Basis of Elite Performance, London, UK, 2016, 2016Conference Paper, 2016
  • McDermott A, Nevin A, Gildea N, Rocha J, O'Shea D, Egaña M., Muscle deoxygenation during ramp incremental cycle exercise in older adults with type 2 diabetes., European Journal of Applied Physiology , 2023Journal Article, 2023
  • Rocha J, Gildea N, O'Shea D, Green S, Egaña M, Priming exercise accelerates oxygen uptake kinetics during high-intensity cycle exercise in middle-aged individuals with type 2 diabetes., Frontiers in Physiology, 18, (13), 2022Journal Article, 2022
  • Gildea N, Rocha J, O'Shea D, Green S & Egaña M, Influence of priming exercise on oxygen uptake and muscle deoxygenation kinetics during moderate-intensity cycling in type 2 diabetes., Journal of Applied Physiology, 127, (4), 2019, p1140 - 1149Journal Article, 2019
  • Murphy E, Rocha J, Gildea N, Green S and Egaña M., Venous occlusion plethysmography vs. Doppler ultrasound in the assessment of leg blood flow kinetics during different intensities of calf exercise., European Journal of Applied Physiology , 118, (2), 2018, p249 - 260Journal Article, 2018

Research Expertise

Dr. Gildea's research interests in type 2 diabetes also extend to understanding the cellular mechanisms that influence macro- and microvascular function within prediabetes and ageing and the effect of different exercise training and lifestyle interventions on vascular and metabolic adaptations therein. Her work is focused on how personalised exercise prescription and other novel therapeutic interventions can improve both glycaemic and blood pressure control and reduce modifiable cardiovascular and cerebrovascular risk factors that are central to reducing the burden of prediabetes, and its progression to overt type 2 diabetes, in a plight for healthy ageing. Given the increased propensity for the development of cerebrovascular disease in both type 2 diabetes and prediabetes, therapeutic interventions to either, help restore decreased cerebrovascular function, or ameliorate further deficits leading to potential cognitive decline are paramount in these burgeoning populations. Dr. Gildea hopes to bolster current efforts to advance translational science and global health by addressing the dose-response relationship of exercise on cerebrovascular health in accordance with disease and population specificity. Ultimately serving to delay potential stroke, cognitive decline and/or dementia in those living with type 2 diabetes or prediabetes, and subsequently bestow corresponding benefits upon patient's families, the healthcare system, and society in general.