Dr. Sean Kennelly

Dr. Sean Kennelly

Clinical Associate Professor, Medical Gerontology

Clinical Associate Professor

https://www.tcd.ie/medicine/research/researchers/SEKENNEL

Biography

Professor Sean Kennelly MB BCh BAO PhD FRCP(Lond) FRCPI is a consultant physician in geriatric and stroke medicine in Tallaght University Hospital (TUH) and Clinical Associate Professor of Medical Gerontology in Trinity College. He is Director of the Institute for Memory and Cognition, and the Cognitive Clinical Trials Unit in Tallaght University Hospital, Dublin. He is clinical director of the National Intellectual Disability Memory Service in TUH. He is co-lead investigator on HRB-funded Dementia Trials Ireland, a national clinical trials network, and is principle investigator on HRB-funded of Dementia Research Network Ireland (DRNI). A fellow of the Royal College of Physicians in London & Ireland, he has extensively published in his main research areas of Ageing, brain health, dementia, and Inflammaging. He has served as chief and principal investigator on several international clinical trials in early-stage Alzheimer's disease. He is principle investigator and lead-clinical advisor on several industry collaborations investigating novel applications of digital gait and speech biomarkers in detection of cognitive decline. He is a member of the clinical and research advisory panel for the Alzheimer's Society Ireland and a principal investigator in the Trinity College Institute of Neuroscience. He is a faculty member for the Global Brain Health Institute in Trinity College Dublin. He is a member of the clinical and research advisory panel for the Alzheimer's Society of Ireland. He is on several clinical and service advisory committees for the national clinical program for older people and the national dementia office. He is a member of the national dementia strategy monitoring group within the department of health. He served as associate dean of higher specialty training in general internal medicine in the Royal College of Physicians of Ireland 2017-2021.

Publications and Further Research Outputs

  • Briggs R, Coary R, Collins R, Coughlan T, O'Neill D, Kennelly SP, Acute hospital care: How much activity is attributable to caring for patients with dementia?, QJM : monthly journal of the Association of Physicians, 109, (1), 2016, p41 - 44Journal Article, 2016, DOI , URL
  • O'Shea E, Timmons S, Kennelly S, Siún A, Gallagher P, O'Neill D, Symptom Assessment for a Palliative Care Approach in People With Dementia Admitted to Acute Hospitals: Results From a National Audit., Journal of geriatric psychiatry and neurology, 2015Journal Article, 2015, DOI , URL
  • Fallon A, Armstrong J, Coughlan T, Collins DR, O'Neill D, Kennelly SP, Characteristics and Outcomes of Older Patients Attending an Acute Medical Assessment Unit., Irish medical journal, 108, (7), 2015, p210-1Journal Article, 2015, URL
  • Dyer AH, Nabeel S, Briggs R, O'Neill D, Kennelly SP, Cognitive assessment of older adults at the acute care interface: the informant history., Postgraduate medical journal, 2016Journal Article, 2016, DOI , URL
  • Gallagher P, Curtin D, de Siún A, O'Shea E, Kennelly S, O'Neill D, Timmons S, Antipsychotic prescription amongst hospitalized patients with dementia., QJM : monthly journal of the Association of Physicians, 2016Journal Article, 2016, DOI , URL
  • Dyer AH, Briggs R, Nabeel S, O'Neill D, Kennelly SP, The Abbreviated Mental Test 4 for cognitive screening of older adults presenting to the Emergency Department., European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2016Journal Article, 2016, DOI , URL
  • Fallon A, Kennelly S, O'Neill D, Frailty in Emergency Departments, Lancet, 87, (10029), 2016, p1720Journal Article, 2016, DOI , URL
  • Briggs R, O'Shea E, de Siún A, O'Neill D, Gallagher P, Timmons S, Kennelly S, Does admission to a specialist geriatric medicine ward lead to improvements in aspects of acute medical care for older patients with dementia?, International journal of geriatric psychiatry, 2016Journal Article, 2016, DOI , URL
  • Timmons S, O'Shea E, O'Neill D, Gallagher P, de Siún A, McArdle D, Gibbons P, Kennelly S, Acute hospital dementia care: results from a national audit., BMC geriatrics, 16, (1), 2016, p113Journal Article, 2016, DOI , URL
  • Briggs R, Kennelly SP, O'Neill D, Drug treatments in Alzheimer's disease., Clinical medicine (London, England), 16, (3), 2016, p247-53Journal Article, 2016, DOI , URL
  • Briggs R, Dyer A, Nabeel S, Collins R, Doherty J, Coughlan T, O'Neill D, Kennelly SP, Dementia in the Acute Hospital: The prevalence and clinical outcomes of acutely unwell patients with dementia., QJM : monthly journal of the Association of Physicians, 2016Journal Article, 2016, DOI , URL
  • Briggs R, Kenny R.A, Kennelly S.P, Systematic Review: The Association between Late Life Depression and Hypotension, Journal of the American Medical Directors Association, 17, (12), 2016, p1076 - 1088Journal Article, 2016, DOI , URL
  • Meulenbroek O, O'Dwyer S, De Jong D, Van Spijker G, Kennelly S, Cregg F, Rikkert M.O, Abdullah L, Wallin A, Walsh C, Coen R, Kenny R.A, Daly L, Segurado R, Borjesson-Hanson A, Crawford F, Mullan M, Lucca U, Banzi R, Pasquier F, Breuilh L, Riepe M, Kalman J, Molloy W, Tsolaki M, Howard R, Jessica Adams M.O, Gaynor S, Lawlor B, European multicentre double-blind placebo-controlled trial of Nilvadipine in mild-to-moderate Alzheimer's disease - The substudy protocols: NILVAD frailty; NILVAD blood and genetic biomarkers; NILVAD cerebrospinal fluid biomarkers; NILVAD cerebral blood flow, BMJ Open, 6, (7), 2016Journal Article, 2016, DOI , URL , TARA - Full Text
  • Grey T, Kennelly S, de Freine P, Mahon S, Mannion V, O'Neill D, Towards a building typology and terminology for Irish hospitals, Irish Journal of Medical Science, 2017Journal Article, 2017, DOI , URL
  • Miller, A.M., Begley, E., Coen, R.F., Doyle, M., Dunne, J., Hutchinson, S., Kennelly, S.P., Kenny, R.A., Killeen, R.P., O'Dwyer, S., O'Neill, C., O'Sullivan, S.S., Rowan, M.J., Sheehy, N., McGuigan, C., Lawlor, B.A. , Clinical consensus guidelines on the application of cerebrospinal fluid biomarkers for Alzheimer's disease diagnosis: recommendations of the Irish Network for Biomarkers in Neurodegeneration., Irish Medical Journal, 109, (10), 2016, p1-13Journal Article, 2016, URL
  • Briggs R, Coughlan T, Doherty J, Collins DR, O'Neill D, Kennelly SP, Investigation and diagnostic formulation in patients admitted with transient loss of consciousness. , Ir Med J, 110, (5), 2017, p563Journal Article, 2017, URL
  • Briggs R, Kenny R.A, Kennelly S.P, Does baseline hypotension predict incident depression in a cohort of community-dwelling older people? Data from The Irish Longitudinal Study on Ageing (TILDA), Age and Ageing, 46, (4), 2017, p648 - 653Journal Article, 2017, DOI , URL , TARA - Full Text
  • Briggs R, McHale C, Fitzhenry D, O'Neill D, Kennelly S, Dementia, disclosing the diagnosis, QJM, 2018Journal Article, 2018, DOI , URL
  • Fitzpatrick D, Ibrahim E, Kennelly S, O'Neill D, Sherlock M, Structuring diabetes mellitus care in long term nursing home residents, European Geriatric Medicine, 13th International Congress of the European Geriatric Medicine Society, Nice, 20-22 Sept 2017, 8, (Suppl 1), 2017, pps140Meeting Abstract, 2017
  • Subbe CP, Kellett J, Barach P, Chaloner C, Cleaver H, Cooksley T, Korsten E, Croke E, Davis E, De Bie AJ, Durham L, Hancock C, Hartin J, Savijn T, Welch J; Crisis Checklist Collaborative, Crisis checklists for in-hospital emergencies: expert consensus, simulation testing and recommendations for a template determined by a multi-institutional and multi-disciplinary learning collaborative., BMC health services research, 2017Journal Article, 2017, DOI
  • Fallon A, Kilbane L, Briggs R, Dyer A, Nabeel S, McElwaine P, Collins DR, Coughlan T, O'Neill D, RyanD, Kennelly SP, Screening for frailty in older emergency department patients: The utility of the Survey of Health, Ageing and Retirement in Europe Frailty Instrument (SHARE-FI) , QJM, 2018Journal Article, 2018, DOI , URL
  • Smyth H, Kennelly SP, O'Neill D, Modern Approaches To Self-Neglect, Ir Med J, 111, (5), 2018, pP748Journal Article, 2018, URL
  • Briggs R, Carey D, O'Halloran A, Kenny RA, Kennelly SP, Validation of the 8-item Centre for Epidemiological Studies Depression Scale in a cohort of community-dwelling older people: data from The Irish Longitudinal Study on Ageing (TILDA) , European Geriatric Medicine, 9, (1), 2018, p121-126Journal Article, 2018, DOI , URL
  • Briggs R, Carey D, Kenny RA, Kennelly SP, What is the Longitudinal Relationship between Gait Abnormalities and Depression in a Cohort of Community-Dwelling Older People? Data From the Irish Longitudinal Study on Ageing (TILDA) , Am J Geriatr Psychiatry, 26 , (1), 2018, p75-86Journal Article, 2018, DOI
  • Dyer AH, Foley T, O'Shea B, Kennelly SP. , Cognitive assessment of older adults in general practice: the collateral history , Ir J Med Sci. , 2018Journal Article, 2018, DOI , URL
  • Peeters G, Leahy S, Kennelly SP, Kenny RA. , Is fear of falling associated with decline in global cognitive functioning in older adults: findings from the The Irish Longitudinal Study on Ageing (TILDA) , J Am Med Dir Assoc., 2018Journal Article, 2018, URL
  • Briggs R, Kennelly SP, Kenny RA. , Does baseline depression increase the risk of unexplained and accidental falls in a cohort of community-dwelling older people? Data from The Irish Longitudinal Study on Ageing (TILDA). , Int J Geriatr Psychiatry., 33, (2), 2018, pe205-e211Journal Article, 2018, DOI
  • Peeters, G. and Leahy, S. and Kennelly, S. and Kenny, R.A., Is Fear of Falling Associated With Decline in Global Cognitive Functioning in Older Adults: Findings From the Irish Longitudinal Study on Ageing, Journal of the American Medical Directors Association, 2017, p1-10Journal Article, 2017, DOI , URL
  • D'Alton M, Coughlan T, Cogan N, Greene S, McCabe DJH, McCarthy A, Murphy S, Walsh R, O'Neill D, Kennelly S, Ryan D, Collins R, Patterns of Mortality in Modern Stroke Care, Ir Med J, 111, (5), 2018, pP750Journal Article, 2018, URL
  • Grey T, Xidous D, Kennelly S, Timmons S, O'Neill D, Dementia friendly hospitals from a Universal Design Approach: research and guidelines, Innovations in Aging, GSA 2018 Annual Scientific Meeting, Boston, 13-17 Nov 2018, 2, (Suppl 1), 2018, pp943Meeting Abstract, 2018, DOI , URL
  • Lawlor B.A., Segurado, R., Kennelly, S., Olde Rikkert, M.G., Howard, R., Pasquier, F., Börjesson-Hanson, A., Tsolaki, M., Lucca, U., D. Molloy, W., Coen, R.F., Riepe, M.W., Kálmán, J., Kenny R.A., Cregg, F., O'Dwyer, S., Walsh C., Adams, J., Banzi, R., Breuilh, L., Daly, L., Hendrix, S., Aisen, P., Gaynor, S., Sheikhi, A., Taekema, D.G., Verhey, F.R., Nemni, R., Nobili, F., Francheschi, M., Frisoni, G., Zanetti, O., Konsta, A., Anastasios, O., Nenopoulou, S., Tsolaki-Tagaraki, F., Pakaski, M., Dereeper, O., de la Sayette, V., Senechal, O., Lavenu, I., Godefroy, O., Calais, G., Crawford, F., Mullan, M., for the NILVAD Study Group. , Nilvadipine in mild to moderate Alzheimer's disease: a randomised controlled trial. , PLOS Medicine , 15, (9), 2018, p1 - 20Journal Article, 2018, TARA - Full Text
  • Briggs R, Carey D, Claffey P, McNicholas T, Donoghue O, Kennelly SP, Kenny RA, Do Differences in Spatiotemporal Gait Parameters Predict the Risk of Developing Depression in Later Life?, J Am Geriatr Soc, 2019Journal Article, 2019, DOI , URL
  • Harkins P, O'Brien H, McCartan D, Nasir N, Twomey B, Srikumar K, Coughlan T, Kennelly S, McElwaine P, O'Neill D, Ryan D, Ronan C, A Hospital Wide Point Prevalence of Adult Urinary Incontinence and Audit of Continence Care., Age and Ageing, 2019Journal Article, 2019, DOI , URL
  • Briggs R, Carey D, Claffey P, McNicholas T, Newman L, Nolan H, Kennelly SP, Kenny RA, The association between frontal lobe perfusion and depressive symptoms in later life., Britis Jounal of Psychiatry, 2018, p1 - 7Journal Article, 2018, DOI , URL
  • Dyer AH, Foley T, O'Shea B, Kennelly SP, Dementia Diagnosis and Referral in General Practice: A Representative Survey of Irish General Practitioners, 2018Journal Article, 2018, URL
  • Briggs R, Carey D, McNicholas T, Claffey P, Nolan H, Kennelly SP, Kenny RA, The association between antidepressant use and orthostatic hypotension in older people: a matched cohort study., Journal of the American Soc Hypertension, 2018Journal Article, 2018, DOI , URL
  • Briggs R, Carey D, Kennelly SP, Kenny RA, Longitudinal Association Between Orthostatic Hypotension at 30 Seconds Post-Standing and Late-Life Depression., Hypertension, 2018, p816-Journal Article, 2018, DOI , URL , TARA - Full Text
  • Briggs R, Tobin K, Kenny RA, Kennelly SP, What is the prevalence of untreated depression and death ideation in older people? Data from the Irish Longitudinal Study on Aging., International Psychogeriatrics, 2018Journal Article, 2018, DOI , URL
  • Devenney KE, Sanders ML, Lawlor B, Olde Rikkert MGM, Schneider S; NeuroExercise Study Group, The effects of an extensive exercise programme on the progression of Mild Cognitive Impairment (MCI): study protocol for a randomised controlled trial., BMC Geriatrics, 17, (1), 2017, p75-Journal Article, 2017, DOI , URL
  • Allen N, Bergin C, Kennelly SP., Malaria in the returning older traveler., 2016Journal Article, 2016, DOI , URL
  • Lawlor B, Kennelly S, O'Dwyer S., NILVAD protocol: a European multicenter double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease., 2016Journal Article, 2016
  • McCabe JJ, Kennelly SP., Acute care of older patients in the emergency department: strategies to improve patient outcomes., 2015Journal Article, 2015, DOI , URL
  • Grace AR, Briggs R, Kieran RE, Corcoran RM, Romero-Ortuno R, Coughlan TL, O'Neill D, Collins R, Kennelly SP., A comparison of beers and STOPP criteria in assessing potentially inappropriate medications in nursing home residents attending the emergency department., 2014Journal Article, 2014, DOI , URL
  • Kennelly SP., Cognitive dysfunction: an important extrahepatic manifestation of hepatitis C infection?, 2013Journal Article, 2013, DOI , URL
  • Kennelly S, Abdullah L, Kenny RA, Mathura V, Luis CA, Mouzon B, Crawford F, Mullan M, Lawlor B., 64. Apolipoprotein E genotype-specific short-term cognitive benefits of treatment with the antihypertensive nilvadipine in Alzheimer's patients--an open-label trial., 2012Journal Article, 2012
  • Xidous D, Grey T, Kennelly SP, O'Neill D, Dementia Friendly Hospital Design: Key Issues for Patients and Accompanying Persons in an Irish Acute Care Public Hospital , Health Environments Research & Design, 13, (1), 2020, p48 - 67Journal Article, 2020, DOI , URL
  • Cognition and Health Aging in, editor(s)Coll, PP , Healthy Aging: A Complete Guide to Clinical Management,, New York, Springer-Verlag New York, 2019, pp169 - 180, [Briggs R, Kennelly S, O'Neill D]Book Chapter, 2019, DOI , URL
  • Peeters G., Feeney J., Carey D., Kennelly S., Kenny R.A., Fear of falling: A manifestation of executive dysfunction?, International Journal of Geriatric Psychiatry, 2019Journal Article, 2019, DOI
  • Dyer AH, Briggs R, Mockler D, Gibney J, Kennelly SP, Non-Pharmacological Interventions for Cognition in Patients with Type 2 Diabetes Mellitus: A Systematic Review., Quarterly Journal Medicine, 2019Journal Article, 2019, DOI
  • Briggs R, Drumm B, Dwyer R, O'Neill D, Kennelly SP, Coughlan T, Collins R, Awareness of atrial fibrillation-effectiveness of a pilot national awareness campaign, Ir J Med Sci, 2019Journal Article, 2019, DOI , URL
  • Dookhy J, McHale C, Kennelly S, Coughlan T, Collins R, Ryan D, O'Neill D, Cardiovascular Risk Profile in People with Mild Cognitive Symptoms Attending a Memory Service - an Opportunity to Promote Brain Health , Age and Ageing, Irish Gerontoloppgical Society 67th Annual Scientific Meeting, Cork, 27-28 Sept 2019, 48, (Suppl 3), 2019, ppiii32-33Meeting Abstract, 2019, DOI
  • Tobin F, McGuinn C, Pearson C, Dooky J, McHale C, Coughlan T, O'Neill D, Ryan D, Collins R, Kennelly S, Does a Pen and Paper Assessment of Executive Skills Correlate with Functional Decline Identified Through Specialised Occupational Therapy Assessment?, Age and Ageing, Irish Gerontoloppgical Society 67th Annual Scientific Meeting, Cork, 27-28 Sept 2019, 48, (Suppl 3), 2019, ppiii54Meeting Abstract, 2019, DOI
  • McHale C, Sharkey J, Coughlan T, O'Neill D, Dookhy J, Sheridan L, Kennelly S, Hearing Loss as a Potentially Modifiable Risk Factor in People with Mild Cognitive Symptoms Attending a Specialist Memory Service, Age and Ageing, Irish Gerontoloppgical Society 67th Annual Scientific Meeting, Cork, 27-28 Sept 2019, 48, (Suppl 3), 2019, ppiii55Meeting Abstract, 2019, DOI
  • Dyer A, Killane I, Bourke N, Woods C, Gibney J, O'Neill D, Reilly R, Kennelly S, Does Dual-Task Gait Speed Predict Cognitive Performance in Midlife Type 2 Diabetes? Baseline Results from the ENBIND Study, Age and Ageing, Irish Gerontoloppgical Society 67th Annual Scientific Meeting, Cork, 27-28 Sept 2019, 48, (Suppl 3), 2019, ppiii3-4Meeting Abstract, 2019, DOI
  • McHale C, McGovern M, Dewergifosse J, Domsa M, McMahon A, Timmons F, Greene J, Tobin F, Bennett A, Donnelly M, Coughlan T, O'Neill D, Dookhy J, Hyland C, Scanlan J, Ryan D, McElwaine P, Kennelly S, Insights into Dementia- An Integrated Care Approach to Family Support, Age and Ageing, Irish Gerontoloppgical Society 67th Annual Scientific Meeting, Cork, 27-28 Sept 2019, 48, (Suppl 3), 2019, ppiii62Meeting Abstract, 2019, DOI
  • Sheridan L, McHale C, Dookhy J, Coughlan T, O'Neill D, Collins R, Ryan D, Kennelly S , Incorporating Neurolinguistics and the Role of Speech and Language Therapy in a Specialist Memory Service , Age and Ageing, Irish Gerontoloppgical Society 67th Annual Scientific Meeting, Cork, 27-28 Sept 2019, 48, (Suppl 3), 2019, ppiii49Meeting Abstract, 2019, DOI
  • Dyer A, Batten I, Killane I, Woods C, Gibney J, O'Neill D, Reilly R, Bourke N, Kennelly S , Linking Diabetes and Dementia Risk: A Role for Aβ-42 Induced Activation of the NLRP3 Inflammasome? Results from the ENBIND Study , Age and Ageing, Irish Gerontoloppgical Society 67th Annual Scientific Meeting, Cork, 27-28 Sept 2019, 48, (Suppl 3), 2019, ppiii26Meeting Abstract, 2019, DOI
  • Gilligan, T.M. and Sibilia, F. and Farrell, D. and Lyons, D. and Kennelly, S.P. and Bokde, A.L.W., No relationship between fornix and cingulum degradation and within-network decreases in functional connectivity in prodromal Alzheimer†s disease, PLoS ONE, 14, (10), 2019Journal Article, 2019, DOI , URL , TARA - Full Text
  • , DEMENTIA FRIENDLY HOSPITALS FROM A UNIVERSAL DESIGN APPROACH: RESEARCH AND GUIDELINES, Innovation in Aging, 2018Journal Article, 2018
  • Fallon A, Dukelow T, Kennelly S, O'Neill D, COVID-19 in Nursing Homes, QJM, 113, (6), 2020, p391 - 392Journal Article, 2020, DOI , URL
  • Dyer AH, Murphy C, Lawlor B, Kennelly SP, NILVAD Study Group., Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD., Journal of the American Medical Directors Association, 21, (2), 2020, p194-200Journal Article, 2020, DOI
  • Dyer AH, Lawlor B, Kennelly SP, NILVAD Study Group., Gait speed, cognition and falls in people living with mild-to-moderate Alzheimer disease: data from NILVAD., BMC geriatrics, 20, (1), 2020, p117Journal Article, 2020, DOI
  • Peeters G, Bennett M, Donoghue OA, Kennelly S, Kenny RA., Understanding the aetiology of fear of falling from the perspective of a fear-avoidance model - A narrative review., Clinical psychology review, 79, 2020, p101862Journal Article, 2020, DOI
  • Bracken-Scally M, Timmons S, O'Shea E, Gallagher P, Kennelly SP, Hamilton V, O'Neill D., Second Irish National Audit of Dementia Care in Acute Hospitals, Offaly, National Dementia Office, 2020, p1 - 228Report, 2020, URL
  • Kennelly SP, Dyer AH, Noonan C, Kennelly SM, Martin A, O'Neill D, Fallon A, Asymptomatic carriage rates and case-fatality of SARS-CoV-2 infection in residents and staff in Irish nursing homes, Age and Ageing, 50, (1), 2021, p49 - 54Journal Article, 2021, DOI , URL
  • Dyer A, McKenna L, Gamage G, Bourke N, Killane I, Widdowson M, Woods C, Gibney J, Reilly R, O'Neill D, Kennelly S. , Cognitive performance in midlife type 2 diabetes: results from the ENBIND study, Diabetic Medicine, 2020Journal Article, 2020, DOI , URL
  • Martin A, Boyle N, Cooke J, Kennelly SP, Martin R, Mulroy M, O'Connor M, O'Keeffe S, O'Neill D on behalf of the Irish Society of Physicians in Geriatric Medicine, Responding to Needs of Residents in Long Term Care in Ireland, Ir Med J, 113, (9), 2020, pP181Journal Article, 2020
  • Anderson DC, Grey T, Kennelly S, O'Neill D, Nursing Home Design and COVID-19: Balancing Infection Control, Quality of Life, and Resilience, Journal of the American Medical Directors Association, 21, (11), 2020, p1519 - 1524Journal Article, 2020, DOI , URL
  • Dyer AH, McKenna L, Batten I, Jones K, Widdowson M, Dunne J, Conlon N, Reilly R, Woods CP, O'Neill D, Gibney J, Bourke NM, Kennelly SP., Peripheral Inflammation and Cognitive Performance in Middle-Aged Adults With and Without Type 2 Diabetes: Results From the ENBIND Study, Front. Aging Neurosci, 12, 2020Journal Article, 2020, DOI , URL
  • Dyer AH, Murphy C, Lawlor B, Kennelly SP, NILVAD StudyGroup, Sedative Load in Community-Dwelling Older Adults with Mild-Moderate Alzheimer's Disease: Longitudinal Relationships with Adverse Events, Delirium and Falls., Drugs & aging, 2020Journal Article, 2020, DOI
  • Dyer AH, Murphy C, Briggs R, Lawlor B, Kennelly SP, NILVAD Study Group, Antidepressant use and orthostatic hypotension in older adults living with mild-to-moderate Alzheimer disease., International journal of geriatric psychiatry, 2020Journal Article, 2020
  • Murphy C, Dyer AH, Lawlor B, Kennelly SP, NILVAD Study Group, Potentially inappropriate medication use in older adults with mild-moderate Alzheimer's disease: prevalence and associations with adverse events., Age and ageing, 2020Journal Article, 2020, DOI , TARA - Full Text
  • Floyd R, Dyer AH, Kennelly SP, Non-pharmacological interventions for cognitive impairment in women with breast cancer post-chemotherapy: A systematic review., Journal of geriatric oncology, 2020Journal Article, 2020
  • Meagher D, Adamis D, Timmons S, O'Regan NA, O'Keeffe S, Kennelly S, Corby C, Meaney AM, Reynolds P, Mohamad M, Glynn K, O'Sullivan R, Developing a guidance resource for managing delirium in patients with COVID-19., Irish journal of psychological medicine, 2020Journal Article, 2020
  • Dyer AH, Murphy C, Lawlor B, Kennelly SP, NILVAD Study Group"", Long-term proton-pump inhibitor use in older adults with mild-to-moderate Alzheimer's disease: Are there cognitive consequences?, European journal of internal medicine, 2020Journal Article, 2020
  • Dyer AH, Murphy C, Lawlor B, Kennelly SP, Study Group For The Nilvad, Social networks in mild-to-moderate Alzheimer disease: longitudinal relationships with dementia severity, cognitive function, and adverse events. , Aging & mental health, 2020Journal Article, 2020
  • Dyer AH, Lawlor B, Kennelly SP, NILVAD Study Group, Sexual dimorphism in the association of APOE "4 genotype with cognitive decline and dementia progression in mild-to-moderate Alzheimer disease., International journal of geriatric psychiatry, 2020Journal Article, 2020
  • Abdullah L, Crawford F, Tsolaki M, Börjesson-Hanson A, Olde Rikkert M, Pasquier F, Wallin A, Kennelly S, Ait-Ghezala G, Paris D, Hendrix S, Mullan M, The Influence of Baseline Alzheimer's Disease Severity on Cognitive Decline and CSF Biomarkers in the NILVAD Trial., Frontiers in neurology, 2020Journal Article, 2020
  • Dyer AH, Murphy C, Segurado R, Lawlor B, Kennelly SP, NILVAD Study Group, Is Ongoing Anticholinergic Burden Associated With Greater Cognitive Decline and Dementia Severity in Mild to Moderate Alzheimer's Disease?, The journals of gerontology. Series A, Biological sciences and medical sciences, 2019Journal Article, 2019
  • Harkins P, O'Brien H, McCartan D, Nasir N, Twomey B, Srikumar K, Coughlan T, Kennelly S, McElwaine P, O'Neill D, Ryan D, Ronan C, Corrigendum: A Hospital Wide Point Prevalence of Adult Urinary Incontinence and Audit of Continence Care., Age and ageing, 2019Journal Article, 2019
  • Mieke Deschodt, Benoit Boland, Cecilia M. Lund, Kai Saks, Venetia-Sofia Velonaki, Olafur Samuelsson, Sean Kennelly, Mark Anthony Vassallo, Gregor Veninšek, Johan Flamaing, Implementation of geriatric care models in Europe (imAGE.eu): a cross-sectional survey in eight countries, European Geriatric Medicine, 9, (6), 2018, p771--782Journal Article, 2018
  • Abdullah L, Crawford F, Langlois H, Tsolaki M, Börjesson-Hanson A, Olde Rikkert M, Pasquier F, Wallin A, Kennelly S, Hendrix S, Blennow K, Lawlor B, Mullan M, Exploratory analyses suggest less cognitive decline with nilvadipine treatment in very mild Alzheimer"s disease subjects, 2018Journal Article, 2018
  • Rashwan, W., Habib, H., Arisha, A., Courtney, G., Kennelly, S., An integrated approach of multi-objective optimization model for evaluating new supporting program in irish hospitals, Proceedings - Winter Simulation Conference, 2017, p1904-1915Journal Article, 2017
  • McCarthy, H., Kennelly, S., Crawford, F., Mullan, M., Cregg, F., Lawlor, B.A., Of dementia: An overview, Drugs of the Future, 42, (5), 2017, p281-284Journal Article, 2017
  • Dyer, A.H., Briggs, R., Nabeel, S., O'Neill, D., Kennelly, S.P., The abbreviated mental test 4 for cognitive screening of older adults presenting to the Emergency Department, European Journal of Emergency Medicine, 24, (6), 2017, p417-422Journal Article, 2017
  • Xidous D, Grey T, Kennelly S, O'Neill D, Understanding the knowledge and engagement of facilities management with dementia- friendly design in Irish hospitals: an exploratory study, Facilities, 9, 2021, p601 - 614Journal Article, 2021, DOI , URL
  • Doyle P, Kennelly S, Ryan D, O'Neill D, Frequency and intensity of medical interventions in a nursing home during COVID-19 Pandemic, European Geriatric Medicine, 16th International E-Congress of the European Geriatric Medicine Society, Virtual, 7-9 Oct, 11, (Suppl 1), 2020, ppS49Published Abstract, 2020, DOI , URL
  • Fallon A, Dyer A, Martin R, Kennelly S, Martin R, O'Neill D, Kennelly S, Profiling COVID-19 infection in Irish nursing homes, European Geriatric Medicine, 16th International E-Congress of the European Geriatric Medicine Society, Virtual, 7-9 Oct, 11, (Suppl 1), 2020, ppS51Published Abstract, 2020, DOI , URL
  • Doyle P, Ryan DJ, Kennelly S, O'Neill D, Frequency and intensity of medical interventions in a nursing home during COVID-19 Pandemic, Ir Med J, 114, (3), 2021, pP301Journal Article, 2021, URL
  • O'Neill D, Kennelly S, Responding to responsive behaviour in Alzheimer's disease, Lancet, 398, (10303), 2021, p842Journal Article, 2021, DOI , URL
  • Waldron, C., Cahill, J., Cromie, S., Delaney, T., Kennelly, S., Pevnick, J., and Grimes, T., Personal Electronic Records of Medications (PERMs) for medication reconciliation at care transitions: a rapid realist review., BMC Medical Informatics and Decision Making , 21, (307), 2021, p1 - 17Journal Article, 2021, DOI , TARA - Full Text
  • Dyer AH, Noonan C, McElheron M, Batten I, Reddy C, Connolly E, Pierpoint R, Murray C, Leonard A, Higgins C, Reilly P, Boran G, Phelan T, McCormack W, O'Neill D, Fallon A, Brady G, O'Farrelly C, Bourke NM, Kennelly SP., Previous SARS-CoV-2 Infection, Age, and Frailty Are Associated With 6-Month Vaccine-Induced Anti-Spike Antibody Titer in Nursing Home Residents, Journal of the American Medical Directors Association, 2022Journal Article, 2022, DOI , URL
  • Grey T, Xidous D, O'Donoghue J, Kennelly S, O'Neill D, Universal Design for Improving Quality of Life and Enhancing COVID-19 Infection Control in Existing Residential Care Settings for Older People: Research Report, Dublin, Centre for Excellence in Universal Design, 2022, p1 - 110Report, 2022, URL
  • Grey T, Xidous D, O'Donoghue J, Kennelly S, O'Neill D, Improving Quality of Life and Enhancing COVID-19 Infection Control in Existing Residential Care Settings for Older People: Universal Design Guidelines, Dublin, Centre for Excellence in Universal Design, 2022, p1 - 44Report, 2022, URL
  • McCabe, J.J., Kennelly, S.P., Acute treatment of elderly patients in the emergency department: Strategies to improve patient outcomes | Akutbehandlung von älteren Patienten in der Notaufnahme: Strategien zur Verbesserung des Patienten-Outcome, Journal fur Anasthesie und Intensivbehandlung, (3), 2015, p23-32Journal Article, 2015
  • Lawlor B, Kennelly S, O'Dwyer S., Correction. NILVAD protocol: a European multicenter double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease., BMJ Open, 5, (9), 2015, pe006364Journal Article, 2015, DOI
  • O'Connell, H., Kennelly, S.P., Cullen, W., Meagher, D.J., Managing delirium in everyday practice: Towards cognitive-friendly hospitals, Advances in Psychiatric Treatment, 20, (6), 2014, p380-389Journal Article, 2014
  • Lawlor B, Kennelly S, O'Dwyer S., Correction. NILVAD protocol: a European multicenter double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease., BMJ Open, 5, (9), 2015, pe006364Journal Article, 2015, DOI
  • Lawlor B, Kennelly S, O'Dwyer S., Correction. NILVAD protocol: a European multicenter double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease., BMJ Open, 5, (9), 2015, pe006364Journal Article, 2015, DOI
  • Dennehy H., Allen A.P., McGlinchey E., Buttery N., Garcia-Dominguez L., Chansler R., Corr C., Dunne P., Kennelly S., Daly L. McCallion P. and McCarron M., A scoping review of post-diagnostic dementia supports for people with intellectual disability, Aging and Mental Health, 2022Journal Article, 2022, URL
  • Donnell DO, Romero-Ortuno R, Kennelly SP, O'Neill D, Donoghue PO, Lavan A, Cunningham C, McElwaine P, Kenny RA, Briggs R., The 'Bermuda Triangle' of orthostatic hypotension, cognitive impairment and reduced mobility: prospective associations with falls and fractures in The Irish Longitudinal Study on Ageing. , Age and Ageing, 52, (2), 2023, pafad005Journal Article, 2023, DOI , URL
  • Murphy C, Dyer AH, Lawlor B, Kennelly SP, for the NILVAD study group, What is the impact of ongoing statin use on cognitive decline and dementia progression in older adults with mild-moderate Alzheimer disease?, PLoS ONE, 2023Journal Article, 2023, DOI
  • Helena Dolphin, Adam H Dyer, Laura Morrison, Susan D Shenkin, Tomas Welsh, Sean P Kennelly, New horizons in the diagnosis and management of Alzheimer"s Disease in older adults, Age and Ageing, 53, (2), 2024Journal Article, 2024, DOI
  • McGlinchey, E., Daly, L., Allen, A., Dennehy, H., Buttery, N., Corr, C., McCallion, P., Kennelly, S., Dunne, P., McCarron, M., Developing Best Practice Guidelines for Post-Diagnostic Dementia Support for People with an Intellectual Disability, 33rd Alzheimer Europe Conference, Helsinki, 16-18 October 2023, 2023Oral Presentation, 2023
  • Kennelly S, O'Neill D, Falls and mobility limitations in older people: measures of higher cerebral integration are also important, Am J Med, 117, (12), 2004, p971 - 971Journal Article, 2004, URL
  • Kennelly SP, Lawlor BA, Kenny RA, Blood pressure and the risk for dementia: a double edged sword., Ageing Research Reviews, 8, (2), 2009, p61-70Journal Article, 2009, DOI
  • Kennelly S, O'Neill D, O'Brien JG, Elder abuse in residential care, Lancet, 377, (9771), 2011, p1076Journal Article, 2011, DOI
  • Kennelly SP, Abdullah L, Paris D, Parish J, Mathura V, Mullan M, Crawford F, Lawlor BA, Kenny RA, Demonstration of safety in Alzheimer's patients for intervention with an anti-hypertensive drug Nilvadipine: results from a 6-week open label study., International journal of geriatric psychiatry, 26, (10), 2011, p1038-45Journal Article, 2011, DOI , URL
  • O'Toole R, O'Neill D, Collins DR, Coughlan T, Kennelly S, Risk of Rehospitalisation from an 'Off-Site' Rehabilitation Unit for Older Adults, Ir Med J, 105, (8), 2012, p285Journal Article, 2012, URL
  • Kennelly S, Abdullah L, Kenny RA, Mathura V, Luis CA, Mouzon B, Crawford F, Mullan M, Lawlor B, Apolipoprotein E genotype-specific short-term cognitive benefits of treatment with the antihypertensive nilvadipine in Alzheimer's patients--an open-label trial., International Journal of Geriatric Psychiatry, 27, (4), 2012, p415-422Journal Article, 2012, DOI
  • Kennelly SP, Morley D, Coughlan T, Collins R, Rochford M, O'Neill D, Knowledge, skills and attitudes of doctors towards assessing cognition in older patients in the emergency department., Postgraduate medical journal, 89, (1049), 2013, p137-41Journal Article, 2013, DOI , TARA - Full Text
  • Kennelly S, Collins O, Walking the cognitive "minefield" between high and low blood pressure., Journal of Alzheimer's disease : JAD, 32, (3), 2012, p609-21Journal Article, 2012
  • Kennelly SP, Lawlor BA, Kenny RA, Blood pressure and dementia - a comprehensive review., Therapeutic advances in neurological disorders, 2, (4), 2009, p241-60Journal Article, 2009
  • Kennelly S, Sweeney N, O'Neill D, Elder abuse: knowledge, skills, and attitudes of healthcare workers., Irish medical journal, 100, (1), 2007, p326Journal Article, 2007
  • Briggs R, Coughlan T, Collins R, O'Neill D, Kennelly SP, Nursing home residents attending the emergency department: clinical characteristics and outcomes., QJM : monthly journal of the Association of Physicians, 2013Journal Article, 2013, DOI , TARA - Full Text
  • Bradley D, Cronin S, Kinsella JA, Tobin WO, Mahon C, O'Brien M, Lonergan R, Cooney MT, Kennelly S, Collins DR, O'Neill D, Coughlan T, Smyth S, McCabe DJ, Frequent inaccuracies in ABCD(2) scoring in non-stroke specialists' referrals to a daily Rapid Access Stroke Prevention service., Journal of the Neurological Sciences, 332, (1-2), 2013, p30-4Journal Article, 2013, DOI , URL , TARA - Full Text
  • Morley D, McNamara P, Kennelly S, McMahon G, Bergin C, Limitations to the identification of HIV-associated neurocognitive disorders in clinical practice., HIV medicine, 14, (8), 2013, p497-502Journal Article, 2013
  • Kennelly SP, Drumm B, Coughlan T, Collins R, O'Neill D, Romero-Ortuno R, Characteristics and outcomes of older persons attending the emergency department: a retrospective cohort study., QJM, 2014Journal Article, 2014, DOI , TARA - Full Text
  • Lawlor B, Kennelly S, O'Dwyer S, Cregg F, Walsh C, Coen R, Kenny RA, Howard R, Murphy C, Adams J, Daly L, Segurado R, Gaynor S, Crawford F, Mullan M, Lucca U, Banzi R, Pasquier F, Breuilh L, Riepe M, Kalman J, Wallin A, Borjesson A, Molloy W, Tsolaki M, Olde Rikkert M, 'NILVAD protocol: a European multicentre double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease.', 2014, - e006364Protocol or guideline, 2014, DOI , TARA - Full Text
  • McCarron, M., Daly, L., McCallion, P., Allen, A.P., Buttery, N., Dennehy, H., Kennelly, S., Corr, C., Dunne, P., McGlinchey, E., Post-Diagnostic Dementia Support Guidelines for People with an Intellectual Disability, 17, Trinity College Dublin, March, 2024Report, TARA - Full Text
  • McCarron, M., Allen, A.P., Buttery, N., Dennehy, H., Kennelly, S., Corr, C., Dunne, P., Daly, L., McCallion P., McGlinchey, E., Voices of Experience: Building Post-Diagnostic Dementia Support Guidelines for People with an Intellectual Disability. Brief Report, 5, Trinity College Dublin, January, 2024Report, DOI , TARA - Full Text

Research Expertise

Dementia Prevention Clinical Trials in Dementia Brain Health Digital Biomarkers of ageing and cognitive decline Dementia in Down Syndrome Changes in Inflammatory System and Vaccine responses within the context of ageing and frailty. Biology of Ageing research

  • Title
    Dementia Trials Ireland
    Summary
    Irelands First Clinical Trial Network for Dementia
    Funding Agency
    HRB
    Date From
    06/2021
    Date To
    06/2026
  • Title
    BRAIN-Diabetes: Border Region Area lifestyle Intervention study for healthy Neurocognitive ageing in diabetes
    Summary
    Multi-domain lifestyle intervention program to prevent cognitive decline in people with Type 2 Diabetes
    Funding Agency
    Cross-border Healthcare Intervention Trials in Ireland Network (CHITIN)
    Date From
    Feb 2019
    Date To
    Sept 2021
  • Title
    Dementia Friendly Irish Hospitals: Opportunities, Barriers, Costs and Solutions
    Summary
    Funding Agency
    Health Research Board
    Date From
    Nov 2015
    Date To
    Nov 2017
  • Title
    A Rapid Realist Review of the Need, Design, Use and Implementation of Electronic Medication Databases in Clinical Practice at Care Transitions
    Summary
    Funding Agency
    Meath Foundation
    Date From
    Sept 2019
    Date To
    Sept 2020
  • Title
    Irish National Audit of Dementia
    Summary
    Funding Agency
    Meath Foundation
    Date From
    July 2013
    Date To
    July 2014
  • Title
    TIDE-AD: Translating Inflammatory Biomarkers to Predict Disease Progression & Adverse Events in Alzheimer Disease
    Summary
    TIDE-AD: Translating Inflammatory Biomarkers to Predict Disease Progression & Adverse Events in Alzheimer Disease
    Funding Agency
    Meath Foundation
    Date From
    11/2021
    Date To
    11/2023
  • Title
    Investigation of early stage memory changes in memory brain networks in Alzheimer's Disease
    Summary
    Funding Agency
    Meath Foundation
    Date From
    July 2017
    Date To
    July 2018
  • Title
    Exploring novel biomarkers of brain health in Diabetes
    Summary
    Investigating the predictive value of gait and inflammatory biomarkers in identifying midlife people with T2DM at risk of cognitive decline.
    Funding Agency
    Meath Foundation
    Date From
    Sept 2019
    Date To
    Sept 2020
  • Title
    Including best practices and the voices of experience in developing post-diagnostic dementia support guidelines for people with an intellectual disability
    Summary
    Development of post-diagnostic support resource for people with intellectual disability living with dementia
    Funding Agency
    HRB HRCI
    Date From
    09/2020
    Date To
    09/2022
  • Title
    Dementia Research Network Ireland
    Summary
    Interdisciplinary Dementia Research Network
    Funding Agency
    HRB
    Date From
    01/2021
    Date To
    01/2024
  • Title
    NH-COVAIR; COVID 19 in Nursing Home Residence; Predicting Disease Severity, Outcomes and Anti-Viral Immune responses
    Summary
    Project investigating relationship between frailty, Clinical outcomes, immunophenotype, and vaccine response in nursing home residents.
    Funding Agency
    Meath Foundation
    Date From
    12/2020
    Date To
    12/2021
  • Title
    Dementia-friendly hospitals: a focus on user centred design
    Summary
    Funding Agency
    Meath Foundation
    Date From
    July 2015
    Date To
    December 2016
  • Title
    Supporting Tallaght University Hospital's (TUH) Integrated Care for Older Persons Service: Identifying the common housing hazards affecting older people in South Dublin
    Summary
    Supporting Tallaght University Hospital's (TUH) Integrated Care for Older Persons Service: Identifying the common housing hazards affecting older people in South Dublin
    Funding Agency
    Meath Foundation
    Date From
    11/2021
    Date To
    11/2022
  • Title
    Including best practices and the voices of experience in developing post-diagnostic dementia support guidelines for people with an intellectual disability
    Summary
    Including best practices and the voices of experience in developing post-diagnostic dementia support guidelines for people with an intellectual disability
    Funding Agency
    HRCI HRB Joint Funding Scheme 2020
    Date From
    09/2022
    Date To
    09/2024
  • Title
    Transcutaneous vagus nerve stimulation in the treatment of mild Alzheimer's disease
    Summary
    Study investigating the feasibility of transcutaneous Vagal nerve stimulation in people with mild cognitive impairment
    Funding Agency
    Meath Foundation
    Date From
    07/2021
    Date To
    07/2023

Mental Health (including Psychiatry and Clinical Psychology), Mental Health (including Psychiatry and Clinical Psychology), Mental Health (including Psychiatry and Clinical Psychology), Neuroscience and clinical neurology, Mental Health (including Psychiatry and Clinical Psychology), Neuroscience and clinical neurology, Neuroscience and clinical neurology, Neuroscience and clinical neurology,