Dr. Aisling O'Halloran

Dr. Aisling O'Halloran

Senior Research Fellow, Medical Gerontology

3531896 4261

Biography

Dr. O'Halloran is a Senior Research Fellow and Biobank Manager with The Irish Longitudinal StuDy on Ageing (TILDA) within the academic unit of Medical Gerontology at Trinity College Dublin and Mercer's Institute for Successful Ageing (MISA) at St. James's Hospital, Dublin. She has been the research lead on both the Frailty and Biomarker Working Groups within TILDA and also manages the TILDA Biobank, the largest of its kind in the Rep. of Ireland. Dr. O'Halloran holds a PhD in the genetic epidemiology of cardiovascular disease from the Royal College of Surgeons in Ireland and a B.A. (Mod) in Natural Science, specializing in Genetics, from Trinity College Dublin. For over fourteen years, Dr. O'Halloran has conducted research on studies of ageing, health epidemiology, immunology and genetics. Her research interests are in the area of frailty and ageing biology in older adults, including related risk factors (biomarkers) and patterns of service use. She has secured a combined peer-reviewed grant portfolio of €1.7 million, including a NIH, SFI and HRB sponsored awards. She has published >30 peer-reviewed articles in international journals. Dr. O'Halloran is also a member of the Executive Committee of the Irish Gerontological Society (IGS) and Associate Editor with the international open access journal BMC Geriatrics.

Publications and Further Research Outputs

  • Peklar J, O'Halloran AM, Maidment ID, Henman MC, Kenny RA, Kos M. , Sedative load and frailty among community-dwelling population aged ≥65 years. , Journal of the American Medical Directors Association, 16, (4), 2014, p282 - 289Journal Article, 2014, DOI
  • Theou O, O'Connell MDL, King-Kallimanis BL, O'Halloran AM, Rockwood K, Kenny RA., Measuring Frailty using Self-report and Test-based Health Measures., Age and Aging, 44, (3), 2015, p471-7Journal Article, 2015, DOI , TARA - Full Text
  • Owusu Akuffo K, Nolan J, Stack J,Moran R, Feeney J,Kenny RA, Peto T, Dooley C, O'Halloran AM, Cronin C, and Beatty S. , Prevalence of age-related macular degeneration in the Republic of Ireland. , British Journal of Ophthalmology, 99, 2015, p1037-1044Journal Article, 2015, DOI , TARA - Full Text
  • Sweeney T, O'Halloran AM, Hamill RM, Davey GC, Gil M, Southwood OI, Ryan MT., . Novel variation in the FABP3 promoter and its association with fatness traits in pigs., Meat Science, (100), 2014, p32 - 40Journal Article, 2014, DOI
  • Leahy S, O' Halloran AM, O' Leary N, Healy M, McCormack M, Kenny RA, O' Connell J., Prevalence and correlates of diagnosed and undiagnosed type 2 diabetes mellitus and pre-diabetes in older adults: Findings from the Irish Longitudinal Study on Ageing (TILDA)., Diabetes research and clinical practice., 110, (3), 2015, p241 - 249Journal Article, 2015, DOI , URL
  • Moran R, Nolan J.M, Stack J, O'Halloran A.M, Feeney J, Akuffo K.O, Kenny R.A, Beatty S, Non-dietary correlates and determinants of plasma lutein and zeaxanthin concentrations in the Irish population, The journal of nutrition, health & aging, 21, (3), 2017, p254 - 261Journal Article, 2017, DOI , URL
  • Ryan MT, O'Halloran AM, Hamill, RM, Davey, GC, Gil M, Southwood OI, Sweeney T. , Polymorphisms in the regulatory region of the porcine MYLPF gene are related to meat 3 quality traits in the Large White breed., Meat Science, 113, 2016, p104 - 106Journal Article, 2016, DOI , URL
  • Murphy C, Shelley E, O Halloran AM, Fahey T, Kenny RA. , Failure to control hypercholesterolaemia in the Irish adult population: Cross-sectional analysis of the baseline wave of The Irish Longitudinal Study on Ageing (TILDA). , Irish Journal of Medical Science, 2017, p1-9Journal Article, 2017, DOI , URL , TARA - Full Text
  • Feeney J, O'Leary N, Moran R, O'Halloran AM, Nolan JM, Beatty S, Young IS, Kenny RA. , Plasma Lutein and Zeaxanthin Are Associated With Better Cognitive Function Across Multiple Domains in a Large Population-Based Sample of Older Adults: Findings from The Irish Longitudinal Study on Aging., The journals of gerontology. Series A, Biological sciences and medical sciences, Jan, 2017, p1-6Journal Article, 2017, DOI , URL
  • O'Halloran AM, Laird E, Healy M, Moran R, Beatty S, Nolan J, Molloy AM, Kenny RA. , Circulating Blood Biomarkers In Older Adults With Frailty: The Irish Longitudinal Study on Ageing (TILDA)., Age and Ageing, Irish Gerontological Society (IGS) 64th Annual Scientific Meeting, Killarney, Kerry, Ireland, 29 Sept - 1st Oct, 45, (S2), Oxford University Press, 2016, ppii13 - ii56Published Abstract, 2016, DOI , URL
  • O'Halloran AM, Laird E, Healy M, Moran R, Beatty S, Nolan J, Molloy AM, Kenny RA., Prevalence Of Micronutrient, Inflammatory Stress, Metabolic And Renal Conditions In Frail Older Adults: The Irish Longitudinal Study on Ageing (TILDA). , Age and Ageing, Irish Gerontological Society (IGS) 64th Annual Scientific Meeting, Killarney, Kerry, Ireland, 29 Sept - 1st Oct, 45, (S2), Oxford University Press, 2016, ppii13 - ii56Published Abstract, 2016, DOI
  • Roe L, O'Halloran AM, Normand C., The Evaluation of the Older People Remaining At Home (Oprah) Project: A Mixed Methods Study., Age and Ageing, Irish Gerontological Society (IGS) 64th Annual Scientific Meeting, Killarney, Kerry, Ireland, 29 Sept - 1st Oct, 45, (S2), Oxford University Press, 2016, ppii1 - ii12Published Abstract, 2016, DOI , URL
  • Moran R, Nolan J, Stack J, O'Halloran AM, Feeney J, Akuffo KO, Kenny RA, Beatty S. , Relationship Between Prevalence (And Awareness)Of Age-Related Macular Degeneration And Plasma Concentrations Of Lutein And Zeaxanthin In An Older Population., Age and Ageing, Irish Gerontological Society (IGS) 64th Annual Scientific Meeting, Killarney, Kerry, Ireland, 29 Sept - 1st Oct, 45, (S2), Oxford University Press, 2016, ppii13 - ii56Published Abstract, 2016, DOI , URL
  • O'Halloran AM, Bressan J, King-Kallimanis BL, O'Connell MDL, Fagan J, Keenan E, Barry J, Kenny RA. , Frailty Is A Marker of Premature Biological Ageing: Preliminary Evidence from The Irish Longitudinal Study of Ageing and a Community-based Methadone Treatment Program., Journal of Frailty and Aging, 3rd International Congress of Frailty and Sarcopenia Research (ICFSR), Boston, USA, 23-25 April, 4, (S1), 2015, pp79-Published Abstract, 2015
  • O'Halloran AM, Roe L, Kenny RA and Normand C., The impact of different measures of frailty on rates of health service use among the community dwelling elderly., Journal of Frailty and Aging, 3rd International Congress of Frailty and Sarcopenia Research (ICFSR), Boston, USA, 23-25 April, 4, (S1), 2015, pp46-Published Abstract, 2015
  • Roe LD, Normand C, Wren MA, Browne J, O'Halloran AM., The impact of frailty on healthcare utilisation in Ireland: evidence from the Irish Longitudinal Study on Ageing. , BMC Geriatrics, 17, (203), 2017Journal Article, 2017, DOI
  • Briggs R, Carey D, O'Halloran A, Kenny RA, Kennelly SP, Validation of the 8-item Centre for Epidemiological Studies Depression Scale in a cohort of community-dwelling older people: data from The Irish Longitudinal Study on Ageing (TILDA) , European Geriatric Medicine, 9, (1), 2018, p121-126Journal Article, 2018, DOI , URL
  • Fiorito, G., Polidoro, S. Dugue, P.A., Kivimaki, M., Ponzi, E., Matullo, G., Guarrera, S., Assummaa, M.B. Georgiadis, P., Kyrtopoulos, S.O. Krogh, V. Palli, D., Panico, S., Sacerdote, C. Tumino, R., Chadeau-Hyam, M., Stringhini, S., Severi, G., Hodge, A.M., Giles, G.G., Marioni, R., Linnér, R.K. O'Halloran, A., Kenny, R.A., Layte, R., McCrory, C., Baglietto, L., Milne, R.L., Vineis, P. (2017)., Social adversity and epigenetic aging: a multi-cohort study on socioeconomic differences in peripheral blood DNA methylation., Scientific Reports, 7, (1), 2017, p16391 - 16395Journal Article, 2017, DOI , URL , TARA - Full Text
  • Moran R, Beatty S, Stack J, O'Halloran AM, Feeney J, Akuffo KO, Peto T, Kenny RA, Nolan JM., The Relationship Between Plasma Concentrations of Lutein and Zeaxanthin with Self-Reported and Actual Prevalence of AMD in an Irish Population-Based Sample., Current eye research, 2017, p383-390Journal Article, 2017, DOI , TARA - Full Text
  • O'Halloran AM, Laird EA, Healy M, Moran R, Nolan J et al, CIRCULATING BIOMARKERS PREDICT INCIDENT FRAILTY: THE IRISH LONGITUDINAL STUDY ON AGEING (TILDA) , Innovation in Aging, 21st International Association of Gerontology and Geriatrics (IAGG) World Congress, San Fransisco, 23-27 July 2017, 1, (1 supplemental), Oxford Academic, 2017, pp23 - 23Published Abstract, 2017, DOI
  • Donoghue O, Setti A, O'Leary N, O'Halloran AM, Kenny R., SELF-REPORTED UNSTEADINESS PREDICTS FEAR-RELATED ACTIVITY RESTRICTION AT TWO YEARS FOLLOW-UP , Innovation in Aging, 21st International Association of Gerontology and Geriatrics (IAGG) World Congress, San Fransisco, 23-27 July 2017, 1, (1 supplemental), Oxford Academic, 2017, pp927 - 928Published Abstract, 2017, DOI
  • Roe LD, O'Halloran AM, Kenny R, Normand C., SUPPORTING OLDER PEOPLE TO AGE IN PLACE IN IRELAND: FRAILTY-RELATED HEALTH CARE USE AND OUTCOMES , Innovation in Aging, 21st International Association of Gerontology and Geriatrics (IAGG) World Congress, San Fransisco, 23-27 July 2017, 1, (1 supplemental), Oxford Academic, 2017, pp1056 - 1056Published Abstract, 2017, DOI
  • Laird, E. and O'Halloran, A.M. and Carey, D. and Healy, M. and O'Connor, D. and Moore, P. and Shannon, T. and Molloy, A.M. and Kenny, R.A., The Prevalence of Vitamin D Deficiency and the Determinants of 25(OH)D Concentration in Older Irish Adults: Data from the Irish Longitudinal Study on Ageing (TILDA), Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 73, (4), 2018, p519-525Journal Article, 2018, DOI , URL
  • Connolly E, Rhatigan M, O'Halloran AM, Muldrew KA, Chakravarthy U, Cahill M, Kenny RA, Doyle SL., Prevalence of age-related macular degeneration associated genetic risk factors and 4-year progression data in the Irish population, British Journal of Ophthalmology, 102, (12), 2018, p1691 - 1695Journal Article, 2018, DOI , URL
  • Laird EJ, O'Halloran AM, Carey D, O'Connor D, Kenny RA, Molloy AM, Voluntary fortification is ineffective to maintain the vitamin B12 and folate status of older Irish adults: evidence from the Irish Longitudinal Study on Ageing (TILDA)., The British journal of nutrition, 2018, p111 - 120Journal Article, 2018, TARA - Full Text
  • Briggs R, McCarroll K, O'Halloran A, Healy M, Kenny RA, Laird E, Vitamin D Deficiency Is Associated With an Increased Likelihood of Incident Depression in Community-Dwelling Older Adults., Journal of the American Medical Directors Association, 20, (5), 2019, p517 - 523Journal Article, 2019, DOI , URL
  • Wong TY, Massa MS, O'Halloran AM, Kenny RA, Clarke R., Cardiovascular risk factors and frailty in a cross-sectional study of older people: implications for prevention., Age and ageing, 47, (5), 2018, p714-720Journal Article, 2018, DOI , TARA - Full Text
  • O'Halloran AM, Laird EJ, Feeney J, Healy M, Moran R, Beatty S, Nolan FM, Molloy AM, Kenny RA. , Circulating micronutrient biomarkers are associated with three measures of frailty: Evidence from The Irish Longitudinal Study on Ageing (TILDA). , JAMDA, 2019Journal Article, 2019, DOI , TARA - Full Text
  • Feeney JC, O'Halloran AM, Kenny RA., The Association Between Hair Cortisol, Hair Cortisone, and Cognitive Function in a Population-Based Cohort of Older Adults: Results From The Irish Longitudinal Study on Ageing., The journals of gerontology. Series A, Biological sciences and medical sciences, 75, (2), 2020, p257-265Journal Article, 2020, DOI
  • Laird EJ, McNicholas T, O'Halloran AM, Healy M, Molloy AM, Carey D, O'Connor D, McCarroll K, Kenny RA., Vitamin D Status Is Not Associated With Orthostatic Hypotension in Older Adults., Hypertension (Dallas, Tex. : 1979), 74, (3), 2019, p639-644Journal Article, 2019, DOI
  • Romero-Ortuno R, Scarlett S, O'Halloran AM, Kenny RA., Is phenotypical prefrailty all the same? A longitudinal investigation of two prefrailty subtypes in TILDA., Age and ageing, 2019Journal Article, 2019, DOI , TARA - Full Text
  • Laird E, O'Halloran AM, Fedorowski A, Melander O, Hever A, Sjögren M, Carey D, Kenny RA., Orthostatic hypotension and novel blood pressure associated gene variants in older adults: data from the TILDA Study., The journals of gerontology. Series A, Biological sciences and medical sciences, 2019Journal Article, 2019, DOI , TARA - Full Text
  • McCrory C, McLoughlin S, O'Halloran AM, Socio-Economic Position Under the Microscope: Getting 'Under the Skin' and into the Cells, Current Epidemiology Reports, 6, (4), 2019, p403 - 411Journal Article, 2019, DOI , URL
  • BMC Geriatrics, Springer Nature, [Associate Editor.], 2018-2020Editorial Board, 2018
  • O'Connor DMA, Laird EJ, Carey D, O'Halloran AM, Clarke R, Kenny RA, Molloy AM., Plasma concentrations of vitamin B12 and folate and global cognitive function in an older population: Cross-sectional findings from The Irish Longitudinal Study on Ageing (TILDA)., The British journal of nutrition, 2020, p1-25Journal Article, 2020, DOI
  • Ward, M; Turner, N; Briggs, R; O'Halloran, A M; Kenny, R A, Resilience does not mediate the association between Adverse Childhood Experiences and later life depression. Findings from The Irish Longitudinal Study on Ageing (TILDA), Journal of Affective Disorders, 2020Journal Article, 2020, DOI
  • McCrory C, Fiorito G, Hernandez B, Polidoro S, O'Halloran AM, Hever A, Ni Cheallaigh C, Lu AT, Horvath S, Vineis P, Kenny RA., GrimAge outperforms other epigenetic clocks in the prediction of age-related clinical phenotypes and all-cause mortality., The Journals of Gerontology. Series A, Biological sciences and medical sciences, 76, (5), 2021, p741 - 749Journal Article, 2021, DOI
  • Georgia Richard, Aisling O'Halloran, Paul Doody, Joseph Harbison, Rose Anne Kenny, Roman Romero-Ortuno, Atrial Fibrillation and Acceleration of Frailty: Findings from The Irish Longitudinal Study on Ageing (TILDA), Age and Ageing, 2021Journal Article, 2021, DOI
  • McCrory C, Fiorito G, O'Halloran AM, Polidoro S, Vineis P, Kenny RA., Early life adversity and age acceleration at mid-life and older ages indexed using the next-generation GrimAge and Pace of Aging epigenetic clocks., Psychoneuroendocrinology, 137, 2021, p105643Journal Article, 2021, DOI
  • O'Connor DMA, Scarlett S, De Looze C, O'Halloran AM, Laird E, Molloy AM, Clarke R, McGarrigle CA, Kenny RA., Low folate predicts accelerated cognitive decline: 8-year follow-up of 3140 older adults in Ireland., European journal of clinical nutrition, 76, (7), 2022, p950 - 957Journal Article, 2022, DOI
  • Palina Piankova, Roman Romero-Ortuno, Aisling M O'Halloran, Biomarker Signatures of Two Phenotypical Pre-Frailty Types in The Irish Longitudinal Study on Ageing, Geriatrics (Basel), 2022Journal Article, 2022, DOI , URL , TARA - Full Text
  • Kim D.J., Massa M.S., Clarke R, Scarlett S, and O'Halloran A.M., Kenny R.A., and Bennett, D, Variability and agreement of frailty measures and risk of falls, hospital admissions and mortality in TILDA, Scientific Reports, 12, (1), 2022Journal Article, 2022, DOI , TARA - Full Text
  • O'Donoghue, P. and O'Halloran, A.M. and Kenny, R.A. and Romero-Ortuno, R., Do the frail experience more adverse events from intensive blood pressure control? A 2-year prospective study in the Irish Longitudinal Study on Ageing (TILDA), eClinicalMedicine, 45, (101304), 2022Journal Article, 2022, DOI , URL
  • Kevin McCarthy, Eamon Laird, Aisling M. O'Halloran, Padraic Fallon, Deirdre O'Connor, Román Romero Ortuño, Rose Anne Kenny, An examination of the prevalence of metabolic syndrome in older adults in Ireland: Findings from The Irish Longitudinal Study on Ageing (TILDA), PLOS ONE, 2022Journal Article, 2022, DOI
  • Caoileann H. Murphy, Eoin Duggan, James Davis, Aisling M. O'Halloran, Silvin P. Knight, Rose Anne Kenny, Sinead N. McCarthy, Roman Romero-Ortuno, Plasma lutein and zeaxanthin concentrations associated with musculoskeletal health and incident frailty in The Irish Longitudinal Study on Ageing (TILDA), Experimental Gerontology, 2022Journal Article, 2022, DOI , TARA - Full Text
  • Eoin Duggan, Caoileann H. Murphy, Silvin P. Knight, James R.C. Davis, Aisling M. O'Halloran, Rose Anne Kenny, Roman Romero-Ortuno, Differential Associations Between Two Markers of Probable Sarcopenia and Continuous Orthostatic Hemodynamics in The Irish Longitudinal Study on Ageing, Journal of Gerontology: Medical Sciences, 2022Journal Article, 2022, DOI , TARA - Full Text
  • Ward M, Briggs R, McGarrigle CA, De Looze C, O'Halloran AM, Kenny RA., The bi-directional association between loneliness and depression among older adults from before to during the COVID-19 pandemic., International journal of geriatric psychiatry, 38, (1), 2023, pe5856Journal Article, 2023, DOI
  • Kevin McCarthy, Eamon Laird, Aisling M. O'Halloran, Padraic Fallon, Román Romero Ortuño, Rose Anne Kenny, Association between metabolic syndrome and risk of both prevalent and incident frailty in older adults: Findings from The Irish Longitudinal Study on Ageing (TILDA), Experimental Gerontology, 2022Journal Article, 2022, DOI
  • Peter Hartley, Faye Forsyth, Aisling O'Halloran, Rose Anne Kenny, Roman Romero-Ortuno, Eight-year longitudinal falls trajectories and associations with modifiable risk factors: evidence from The Irish Longitudinal Study on Ageing (TILDA), Age and Ageing, 2023Journal Article, 2023, DOI , TARA - Full Text
  • Heike C. Hawerkamp, Adam H. Dyer, Neha D. Patil, Matt McElheron, Niamh O'dowd, Laura O'doherty, Aisling Ui Mhaonaigh, Angel M. George, Aisling M. O'halloran, Conor Reddy, Rose Anne Kenny, Mark A. Little, Ignacio Martin-Loeches, Colm J. Bergin, Sean Kennelly, Seamas C. Donnelly, Nollaig Bourke, Aideen Long, Jacklyn Sui, Derek G. Doherty, Niall Conlon, Cliona Ni Cheallaigh and Padraic Fallon, Characterisation of the Pro-Inflammatory Cytokine Signature in Severe COVID-19, Frontiers in Immunology , 2023Journal Article, 2023
  • McCrory, C., McLoughlin, S., Layte, R., Ni Cheallaigh, C., O'Halloran, A.M, Barros, H., Berkman, L.F., Bochud, M., Crimmins, E., Farrell, M., Fraga, S., GrundyE., Kelly-Irving, M., Petrovic, D., Seeman, T., Stringhini, S., Vollenveider, P., Kenny, R.A, Towards a consensus definition of allostatic load: a multi-cohort, multi-system, multi-biomarker individual participant data (IPD ) meta-analysis, Psychoneuroendocrinology, 2023Journal Article, 2023
  • Nowak N, De Looze C, O'Halloran A, Kenny RA, Sexton DJ., The association between kidney function, cognitive function, and structural brain abnormalities in community-dwelling individuals aged 50"+"is mediated by age and biomarkers of cardiovascular disease., Cardiovascular research, 2023, pcvad060Journal Article, 2023, DOI
  • Laird Eamon, O'Halloran Aisling M, Molloy Anne M, Healy Martin, Bourke Nollaig, Kenny Rose Anne, Vitamin D status & associations with inflammation in older adults , PloS one , 18 , (6 ), 2023, pe0287169 -Journal Article, 2023, DOI , URL
  • Laura Orlandini, Enrica Patrizio, Aisling M O'Halloran, Christine A McGarrigle, Roman Romero Ortuno, Rose Anne Kenny, Marco Proietti, Matteo Cesari, Social vulnerability, frailty and self-perceived health: findings from The Irish Longitudinal Study on Ageing (TILDA), The Journal of Frailty & Aging, 2024Journal Article, 2024
  • McCarthy K, O'Halloran AM, Fallon P, Kenny RA, McCrory C., Metabolic syndrome accelerates epigenetic ageing in older adults: Findings from The Irish Longitudinal Study on Ageing (TILDA)., Experimental gerontology, 183, 2023, p112314Journal Article, 2023, DOI , TARA - Full Text
  • De Looze C, McCrory C, O'Halloran A, Polidoro S, Anne Kenny R, Feeney J., Mind versus body: Perceived stress and biological stress are independently related to cognitive decline. , Brain, behavior, and immunity, 2023, pS0889-1591(23)00322-7Journal Article, 2023
  • Feng Xue, Silvin P. Knight, Emma Connolly, Aisling M. O"Halloran, Morgana Afonso Shirsath, Louise Newman, Eoin Duggan, Rose Anne Kenny, Roman Romero-Ortuno, Were Frailty Identification Criteria Created Equal? A Comparative Case Study on Continuous Non-Invasively Collected Neurocardiovascular Signals during an Active Standing Test in the Irish Longitudinal Study on Ageing (TILDA), Sensors, 2024Journal Article, 2024, DOI , URL , TARA - Full Text
  • O'Halloran A.M., Cremers J., Vrangbaek K., Roe L., Bourke R., Mortensen L.H., Westendorp R.G.J., Kenny R.A., Cardiovascular disease and the risk of incident falls and mortality among adults aged " 65 years presenting to the emergency department: a cohort study from national registry data in Denmark, BMC Geriatrics, 24, (1), 2024Journal Article, 2024, DOI
  • Chenhuichen, C. and O†Halloran, A.M. and Lang, D. and Kenny, R.A. and Romero-Ortuno, R., The lived experience of frailty: beyond classification and towards a holistic understanding of health, European Geriatric Medicine, 2024Journal Article, 2024, DOI , URL
  • O'Connor D., Molloy A.M., Laird E., Kenny R.A., O'Halloran A.M., Sustaining an ageing population: The role of micronutrients in frailty and cognitive impairment, Proceedings of the Nutrition Society, 2023Journal Article, 2023, DOI
  • Dolan C, O'Halloran A, Bradley DG, Croke DT, Evans A, O'Brien JK, Dicker P, Shields DC., Genetic stratification of pathogen-response-related and other variants within a homogeneous Caucasian Irish population., European Journal of Human Genetics, 13, (7), 2005, p798 - 806Journal Article, 2005, DOI
  • O'Halloran AM, Pénard N, Galli A, Fan CW, Robertson IH, Kenny RA, Falls and falls efficacy: the role of sustained attention in older adults., BMC geriatrics, 11, (85), 2011, p10Journal Article, 2011, DOI , URL , TARA - Full Text
  • O'Halloran AM, Fan CW, Kenny RA, Pénard N, Galli A, Robertson IH., Variability in sustained attention and risk of frailty., Journal of the American Geriatric Society, 59, (12), 2011, p2390 - 2392Journal Article, 2011, DOI , URL
  • O'Halloran AM, Patterson CC, Horan P, Maree A, Curtin R, Stanton A, McKeown PP, Shields DC., Genetic polymorphisms in platelet-related proteins and coronary artery disease: investigation of candidate genes, including N-acetylgalactosaminyltransferase 4 (GALNT4) and sulphotransferase 1A1/2 (SULT1A1/2)., Journal of Thrombosis and Thrombolysis, 27, (2), 2009, p175 - 184Journal Article, 2009, DOI , URL
  • O'Halloran AM, Stanton A, O'Brien E, Shields DC., The impact on coronary artery disease of common polymorphisms known to modulate responses to pathogens., Annals of Human Genetics, 70, (6), 2006, p934 - 945Journal Article, 2006, DOI , URL
  • O'Halloran AM, Curtin R, O'Connor F, Dooley M, Fitzgerald A, O'Brien JK, Fitzgerald DJ, Shields DC., The impact of genetic variation in the region of the GPIIIa gene, on Pl expression bias and GPIIb/IIIa receptor density in platelets., British Journal of Haematology, 132, (4), 2006, p494 - 502Journal Article, 2006, DOI , URL
  • Shields DC, O'Halloran AM., Integrating genotypic data with transcriptomic and proteomic data., Comparative and Functional Genomics, 3, (1), 2002, p22 - 27Review Article, 2002, DOI , URL , TARA - Full Text
  • Ryan MT, Hamill RM, O'Halloran AM, Davey GC, McBryan J, Mullen AM, McGee C, Gispert M, Southwood OI, Sweeney T, SNP variation in the promoter of the PRKAG3 gene and association with meat quality traits in pig., BMC Genetics, 13, (66), 2012, p17Journal Article, 2012, DOI , URL , TARA - Full Text
  • O'Halloran AM, Finucane C, Savva GM, Robertson IH, Kenny RA., Sustained Attention and Frailty in the Older Adult Population., Journals of Gerontology B Psychological Sciences and Social Sciences. , 69, (2), 2014, p147 - 155Journal Article, 2014, DOI
  • O'Halloran AM, Kenny, RA, King-Kallimanis BL. , The latent factors of depression from the short forms of the CES-D are consistent, reliable and valid in community-living older adults. , European Geriatric Medicine, 5, (2), 2014, 97-102Journal Article, 2014, DOI , TARA - Full Text
  • Greene BR, Doheny EP, O'Halloran AM, Kenny RA., Frailty status can be accurately assessed using inertial sensors and the TUG test. , Age and Ageing, 43, (3), 2014, p406 - 411Journal Article, 2014, DOI , URL , TARA - Full Text
  • O'Halloran AM, King-Kallimanis BL, O'Connell MDL, Robertson IH, and Kenny RA., Sustained attention correlates with two models of frailty At baseline and follow-up: the irish longitudinal study of ageing., Journal of Frailty and Aging, International Conference of Frailty and Sarcopenia Research, Barcelona, Spain, March 12-14, edited by Cesari M , 3, (1), Serdi Edition, 2014, pp34 - 34Published Abstract, 2014, URL , TARA - Full Text
  • Peklar, J, O'Halloran AM, Kos M, Henman MC, Maidment I, Kenny RA, Frailty syndrome and sedative load of drugs, Journal of Frailty and Aging, International Conference on Frailty and Sarcopenia Research, Barcelona, Spain, March 12-14, edited by Cesari M , 3, (1), Serdi Edition, 2014, pp54 - 54Published Abstract, 2014, URL , TARA - Full Text
  • O'Halloran, A.M., O'Connell, M.D.L., Finucane, C., Savva, G.M., Robertson, I.H., Kenny, R.A. , The Relationships Between Executive Function, Cognitive Processing Speed And Two Models of Frailty Are Mediated By Sustained Attention In The Older Adult Population. , European Geriatric Medicine, 8th Congress of the European Union Geriatric Medicine Society (EUGMS), Venice, Italy, October 2-4, edited by Michel, J-P , 4, (S1), Elsevier, 2013, ppS70-Published Abstract, 2013, URL , TARA - Full Text
  • O'Halloran, A.M., Kallimanis, B.L., Kenny, R.A. , The Impact of Positive Affect on Falls and Fear of Falling in the Older Adult Population. , Age and Ageing, British Geriatric Society (BGS), Annual Meeting, Harrogate, UK, November 28-30, 2012, edited by Stott, DJ , 42, (S2), Oxford Journals, 2013, ppii20-Published Abstract, 2013, URL , TARA - Full Text
  • O'Halloran, A.M., Kenny, R.A., King-Kallimanis, B.L., The Factor Structure of the Long and Short Forms of the CES-D Scale and the Validity of Positive Affect in Older Irish Adults., Age and Ageing, British Geriatric Society (BGS), Spring Meeting, Belfast, UK, April 18-19, 2013, edited by Stott, DJ , 45, (S3), Oxford Journals, 2013, ppii27-Published Abstract, 2013, URL , TARA - Full Text
  • O'Halloran, A.M., Finucane, C., Savva, G.M., Robertson, I.H., Kenny, R.A. , Sustained Attention Is Associated With Frailty In The Older Adult Population. , European Geriatric Medicine, 8th Congress of the European Union Geriatric Medicine Society (EUGMS), Brussels, Belgium, September 26-28, edited by Michel, J-P , 3, (S1), Serdi Edition, 2012, ppS16-Published Abstract, 2012, URL , TARA - Full Text
  • O'Halloran, A.M., Treacy, K., Cunningham, C., Crosby, L., Walsh, C., Fan, C.W., Kenny, R.A. , The Impact of Positive Affect on Falls Efficacy in the Older Adult Population. , European Geriatric Medicine, 8th Congress of the European Union Geriatric Medicine Society (EUGMS), Brussels, Belgium, September 26-28, edited by Michel, J-P , 3, (S1), Serdi Edition, 2012, ppS137-Published Abstract, 2012, URL , TARA - Full Text
  • O'Halloran, AM, Recognising Frailty: Insights from The Irish Longitudinal Study on Ageing (TILDA)., : Integrated Care Approach for Frailty in the Older Person Conference. , Galway, Ireland, March 8th , 2017, Health Service Executive and Saolta Hospital Group, 1ppInvited Talk
  • Roe L, O'Halloran AM, Normand C, Murphy C., The impact of frailty on public health nurse service utilisation. Findings from The Irish Longitudinal Study on Ageing (TILDA). , Dublin, Ireland, The Irish Longitudinal Study on Ageing., September, 2016, 1-28Report, URL
  • O'Halloran AM, Frailty and Falls in Ireland North and South: Preliminary Evidence from TILDA and NICOLA. , Joint Public Health Conference. , Belfast, UK, 8th November, 2018, Public Health Agency Northern Ireland and Health Service ExecutiveInvited Talk
  • O'Halloran AM, Targeting Frailty to Prevent Disability: Insights from The Irish Longitudinal Study on Ageing (TILDA). , National Disability Authority Annual Conference, Dublin, Ireland, 25th September, 2018, National Disability AuthorityInvited Talk
  • Daniel Carey, Orna Donoghue, Sarah Gibney, Joanne Feeney, Rose Anne Kenny, Eamon Laird, Christine McGarrigle, Sinead McLoughlin, Triona McNicholas, Irene Mosca, Charles Normand, Aisling O'Halloran, Mary O'Shea, Lorna Roe, Siobhan Scarlett, Katie Tobin, Stephen Thomas, Dominic Trepel, Niall Turner, Mark Ward, Wellbeing And Health In Ireland's Over 50s 2009-2016. , Dublin, Ireland, The Irish Longitudinal Study on Ageing 2018, November, 2018Report, URL
  • Tools for Assessing Frailty in Older People: General Concepts. in, editor(s)Nicola Veronese , Frailty and Cardiovascular Diseases, Switzerland, Springer, Cham, 2020, pp9 - 19, [Martin FC, O'Halloran AM.]Book Chapter, DOI , URL
  • O'Halloran AM, Frailty in Ireland - A developing landscape, Paul Wagstaff Commemorative Lecture, Dublin, Ireland, 9th September , 2019, Irish Society of Chartered PhysiotherapistsInvited Talk
  • Aisling O'Halloran, Mature Matters: Ageing, 2012, - 1Miscellaneous, URL , TARA - Full Text
  • Aisling M. O'Halloran, Falls and Frailty in Ireland - Evidence from the Irish Longitudinal Study on Ageing (TILDA), AGM of Chartered Physiotherapists of Ireland in Neurology and Gerontology, Dublin, Ireland, May 17, 2014, Chartered Physiotherapists of IrelandInvited Talk

Research Expertise

Her current research interest is in the biology of ageing, including frailty, falls, resilience and well-being. She has a particular interest in characterizing biomarkers (genes, proteins, metabolites, processes) implicated in these age-related disorders. The goal of her research is to identify early biomarkers for use in screening and intervention in the progression of frailty and investigate patterns of health care use. This work will inform frailty detection/prevention/intervention, frailty-related health service use and provision and raise public awareness of frailty on the island of Ireland.

  • Title
    Frailty-related Outcomes and health Care USe (FOCUS)
    Summary
    Funding Agency
    Health Service Executive (HSE)
    Date From
    February 2016
    Date To
    July 2017
  • Title
    Frailty in Ireland North and South
    Summary
    The unprecedented global increase in life expectancy over the past century has lead to a rapidly expanding ageing population, placing ever higher demands on publicly-funded healthcare resources in Ireland, North and South. Current trajectories indicate that such demands are unsustainable. Early identifiers of declining health will be central to measuring health risk. The European Innovation Partnership on Active and Healthy Ageing has highlighted frailty as key to seeking a two year increase in healthy life years by 2020. Resilience and frailty represent opposite ends of a spectrum of decline from robust health to profound functional dependence. Frailty is a driver of functional and cognitive decline, predicting multi-morbidity, disability, increased health care utilisation and mortality (Fried et al, 2001, 2004). However, frailty can be ameliorated by early detection and intervention. Data from The Irish Longitudinal Study of Ageing (TILDA) will be used to track transitions along the frailty spectrum and investigate how frailty-related biomarker profiles of physical, cognitive and psychological health at baseline (Wave 1) change and predict frailty during follow-up (Waves 2 and 3). North-South comparisons between the prevalence and characteristics of frailty using Wave 3 of TILDA and Phase 1 of the Northern Ireland Cohort for Longitudinal Ageing (NICOLA), which coincide during 2014. Will be performed. Elucidating frailty-related risk factors and resource demands in the ageing population will help to identify: (1) new evidence-based targets for pre-clinical frailty detection and intervention, and (2) specific needs that will be vital in delivering efficient, effective healthcare services and increasing healthy life-years into the future
    Funding Agency
    CARDI - Centre for Ageing Research in Ireland
    Date From
    March 2014
    Date To
    February 2017
  • Title
    The Irish Longitudinal Ageing Study (TILDA) Nutritional Biomarker Database Enhancement Initiative (BIO-TILDA)
    Summary
    Funding Agency
    Dept. of Agriculture, Food and Marine (DARM)
    Date From
    January 2014
    Date To
    January 2016

Immunity and Infection (including Rheumatology & Inflammatory disease), Other Health Sciences, Health Care & Health Services (including Health Technology and Health Information Systems), Neuroscience and clinical neurology, Other Clinical Medicine, Genetics and Genomics, Mental Health (including Psychiatry and Clinical Psychology), Other Basic Medicine, Biochemistry, Molecular & Cellular Biology,

Recognition

  • Best Presentation Medal at Irish Gerontological Society Annual Scientific Meeting, Kilarney 01/10/2016
  • Commendation Award for Scientific Presentation at Irish Gerontological Society Annual (IGS) Scientific Meeting, Dublin September 2011
  • America-Ireland Fund Undergraduate Scholarship Award, Smurfit Institute of Genetics, Trinity College Dublin and School of Medicine, Washington University, St. Louis, Missouri, USA May 1998
  • CARDI Ageing Research Leadership March 2014
  • Best Research Presentation. Medical Gerontology Annual Research Meeting, Trinity College, Dublin March 2012
  • Best Abstract Award at Falls Frailty and Bone Health Europe Conference, Dublin. 10/11/2017
  • Department of Agriculture Fisheries and the Marine (DAFM) FIRM/RSF/CoFoRD 2013 Research Award December 2013
  • National Institute of Ageing (NIA) Biomarker Network.
  • Irish Frailty Network (IFN) - Founding Member present
  • Irish Gerontological Society Member of Executive Committee (2016 - present) present
  • Irish Society of Immunology
  • European Union Geriatric Medicine Society (EUGMS)
  • Gerontological Society of America (GSA)
  • British Geriatrics Society (BGS)