Dr. Henry Windle

• Burrows, A.D., Jurcic, M., Mahon, M.F., Pierrat, S., Roffe, G.W., Windle, H.J., Spencer, J., Bismuth coordination networks containing deferiprone: synthesis, characterisation, stability and antibacterial activity., Dalton Transactions, 44, (31), 2015, p13814 - 13817Journal Article, 2015, DOI
• Xiaofang Liu, Helena Jahuira, Robert Gilman, Alicia Alva, Lilia Cabrera, Michiko Okamoto, Hang Xu, Dermot Kelleher, Henry Windle, Marco Varela, Manuela Verastegui, Maritza Calderon, Gerardo Sanchez, Vanessa Sarabia, Sarah Ballard, Caryn Bern, Holger Mayta, Jean Crabtree, Vita Cama, Mayuko Saito, and Hitoshi Oshitani , Etiological role and repeated infections of sapovirus among children aged less than two years in a cohort study in a peri-urban community of Peru, Journal of Clinical Microbiology, 54, (6), 2016, p1598-604Journal Article, 2016, DOI
• Windle HJ*, Ang YS*, Athie Morales V, McManus R*, Kelleher DP , Human peripheral and gastric lymphocyte responses to Helicobacter pylori NapA and AphC differ in infected and uninfected individuals, Gut, 54, (1), 2005, p25 - 32Journal Article, 2005, DOI , TARA - Full Text
• B. Mee, D. Kelleher, J. Frias, R. Malone, K.F. Tipton, G.T. Henehan, H.J. Windle., Characterization of cinnamyl alcohol dehydrogenase of Helicobacter pylori: an aldehyde dismutating enzyme., FEBS J., 272, (5), 2005, p1255 - 1264Journal Article, 2005
• Windle HJ, Ang YS, Morales VA, McManus R, Kelleher D, Human peripheral and gastric lymphocyte responses to Helicobacter pylori NapA and AphC differ in infected and uninfected individuals, Gut, 54, (1), 2005, p25 - 32Journal Article, 2005
• Abdel-Latif MM, Windle HJ, Fitzgerald KA, Ang YS, Eidhin DN, Li-Weber M, Sabra K, Kelleher D., Helicobacter pylori activates the early growth response 1 protein in gastric epithelial cells., Infect. Immun., 72, (6), 2004, p3549 - 3560Journal Article, 2004
• Filson H, Fox A, Kelleher D, Windle HJ, Sanders DA. , Purification, crystallization and preliminary X-ray analysis of an unusual thioredoxin from the gastric pathogen Helicobacter pylori., Acta Crystallogr D Biol Crystallogr, 59, (7), 2003, p1280 - 1282Journal Article, 2003
• Terres AM, Windle HJ, Ardini E, Kelleher DP., Soluble extracts from Helicobacter pylori induce dome formation in polarized intestinal epithelial monolayers in a laminin-dependent manner., Infect. Immun., 71, (7), 2003, p4067 - 4078Journal Article, 2003
• Redpath MB, Windle H, Nolan D, Pays E, Voorheis HP, Carrington M., ESAG11, a new VSG expression site-associated gene from Trypanosoma brucei., Mol Biochem Parasitol, 111, (1), 2000, p223 - 228Journal Article, 2000
• Windle HJ, Fox A, Ni Eidhin D, Kelleher D., The thioredoxin system of Helicobacter pylori., J. Biol. Chem., 275, (7), 2000, p5081 - 5090Journal Article, 2000
• Windle HJ, Kelleher D. , Identification and characterization of a metalloprotease activity from Helicobacter pylori., Infect. Immun., 65, (8), 1997, p3132 - 3137Journal Article, 1997
• Lynch M, Walsh TA, Marszalowska I, Webb AE, MacAogain M, Rogers TR, Windle H, Kelleher D, O'Connell MJ, Loscher CE., Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response., BMC Evolutionary Biology, 17, (1), 2017, p90-Journal Article, 2017, DOI
• Isolation of outer membrane vesicles from Helicobacter pylori. in, editor(s)Sinead M Smith , Methods in Molecular Biology: Helicobacter pylori: Methods and Protocols, Springer, 2019, [Henry Windle]Book Chapter, 2019
• Munshi RM, Windle HJ, Fusobacterium nucleatum extracellular vesicles: a role in host-pathogen interaction, Journal of Extracellular vesicles, 2019Journal Article, 2019
• M. M. Abdel-Latif, J. O'Riordan, H. J. Windle, E. Carton, N. Ravi, D. Kelleher and J. V. Reynolds, NF-kappaB Activation in Esophageal Adenocarcinoma: Relationship to Barrett's Metaplasia, Survival, and Response to Neoadjuvant Chemoradiotherapy, Annals of surgery, 239, (4), 2004, p491-500Journal Article, 2004, URL
• H. X. Xia, H. J. Windle, D. G. Marshall, C. J. Smyth, C. T. Keane and C. A. O'Morain, Recrudescence of Helicobacter pylori after apparently successful eradication: novel application of randomly amplified polymorphic DNA fingerprinting, Gut, 37, (1), 1995, p30-AprJournal Article, 1995, URL
• M. M. Abdel-Latif, H. J. Windle, K. A. Fitzgerald, Y. S. Ang, D. N. Eidhin, M. Li-Weber, K. Sabra and D. Kelleher, Helicobacter pylori activates the early growth response 1 protein in gastric epithelial cells, Infection and immunity, 72, (6), 2004, p3549-60Journal Article, 2004, URL
• D. P. Nolan, D. G. Jackson, H. J. Windle, A. Pays, M. Geuskens, A. Michel, H. P. Voorheis and E. Pays, Characterization of a novel, stage-specific, invariant surface protein in Trypanosoma brucei containing an internal, serine-rich, repetitive motif, The Journal of biological chemistry, 272, (46), 1997, p29212-21Journal Article, 1997, URL
• D. G. Jackson, H. J. Windle and H. P. Voorheis, The identification, purification, and characterization of two invariant surface glycoproteins located beneath the surface coat barrier of bloodstream forms of Trypanosoma brucei, The Journal of biological chemistry, 268, (11), 1993, p8085-95Journal Article, 1993, URL
• M. B. Redpath, H. Windle, D. Nolan, E. Pays, H. P. Voorheis and M. Carrington, ESAG11, a new VSG expression site-associated gene from Trypanosoma brucei, Molecular and biochemical parasitology, 111, (1), 2000, p223-8Journal Article, 2000, URL
• M. L. Doherty, H. Windle, H. P. Voorheis, H. Larkin, M. Casey, D. Clery and M. Murray, Clinical disease associated with Trypanosoma theileri infection in a calf in Ireland, The Veterinary record, 132, (26), 1993, p653-6Journal Article, 1993, URL
• M. M. Abdel-Latif, J. O'Riordan, H. J. Windle, E. Carton, N. Ravi, D. Kelleher and J. V. Reynolds, NF-kappaB Activation in Esophageal Adenocarcinoma: Relationship to Barrett's Metaplasia, Survival, and Response to Neoadjuvant Chemoradiotherapy, Annals of Surgery, 239, (4), 2004, p491-500Journal Article, 2004, DOI , TARA - Full Text
• A. M. Terres, H. J. Windle, E. Ardini and D. P. Kelleher, Soluble extracts from Helicobacter pylori induce dome formation in polarized intestinal epithelial monolayers in a laminin-dependent manner, Infection and immunity, 71, (7), 2003, p4067-78Journal Article, 2003, DOI , TARA - Full Text
• Papinutto E, Windle HJ, Cendron L, Battistutta R, Kelleher D., Crystal Structure of alkyl hydroperoxide reductase (AphC) from Helicobacter pylori, Biochim Biophys Acta, 1753, 2005, p240 - 246Journal Article, 2005
• Abdel Latif MM, Windle HJ, El Homasany BS, Sabra K, Kelleher D, Caffeic acid phenethyl ester modulates Helicobacter pylori-induced nuclear factor-kappa B and activator protein-1 expression in gastric epithelial cells., British Journal of Pharmacology, 146, 2005, p1139 - 1147Journal Article, 2005
• Human immune responses to Helicobacter pylori infections in, Moran AP & O'Morain CA , Pathogenesis and Host Response in Helicobacter pylori infections, Normed Verlag, 1997, pp148 - 157, [Kelleher D, Windle HJ & Fan XJ]Book Chapter, 1997
• Immunological aspects of H. pylori infection in, Mahida YR , Immunological Aspects of Gastroenterology, The Netherlands, Kluwer Academic Publishers, 2001, pp153 - 175, [Windle HJ, Terrés AM & Kelleher D.]Book Chapter, 2001
• O'Toole D, Abdel-Latif MM, Long A, Windle HJ, Murphy AM, Bowie A, O'neill LA, Weir DG, Kelleher D., Low pH and Helicobacter pylori increase nuclear factor kappa B binding in gastric epithelial cells: A common pathway for epithelial cell injury?, J Cell Biochem., 96, (3), 2005, p589 - 598Journal Article, 2005
• McGee DJ, Kumar S, Viator RJ, Bolland JR, Ruiz J, Spadafora D, Testermn TL, Kelly DJ, Pannell LK, Windle HJ, Helicobacter pylori thioredoxin is an arginase chaperone and guardian against oxidative and nitrosative stresses, J. Biol. Chem., 281, (6), 2006, p3290 - 3296Journal Article, 2006
• Mohamed MM Abdel-Latif, Henry J Windle, Basma S El Homasany, Kamal Sabra, Dermot Kelleher, Caffeic acid phenethyl ester modulates Helicobacter pylori-induced nuclear factor-kappa B and activator protein-1 expression in gastric epithelial cells, British Journal of Pharmacology, 146, (8), 2005, p1139 - 1147Journal Article, 2005, TARA - Full Text
• B Mee, D Kelleher, J Frias, R Malone, KF Tipton, GT Henehan, HJ Windle, Characterization of cinnamyl alcohol dehydrogenase of Helicobacter pylori. An aldehyde dismutating enzyme, FEBS J, 272, (5), 2005, p1255 - 1264Journal Article, 2005, DOI , TARA - Full Text
• Jackson, D. J., Windle, H. J. & Voorheis, H. P., The Identification, Purification and Characterization of Two Invariant Surface Glycoproteins Located beneath the Surface Coat Barrier of Bloodstream Forms of T. brucei, Journal of Biological Chemistry, 268, (11), 1993, p8085 - 8095Journal Article, 1993, URL
• Doherty, M. L., Windle, H. J., Voorheis, H. P., Larkin, H., Casey, M., Clery, D. & Murray, M., Clinical disease associated with Trypanosoma theileri infection in a calf in Ireland, Veterinary Record , 132, (26), 1993, p653 - 656Journal Article, 1993
• Nolan, D., Jackson, D. G., Windle, H. J., Pays, A., Geuskens, M., Michel, A., Voorheis, H. P. and Pays, E., Characterization of a novel, stage-specific, invariant surface protein in Trypanosoma brucei containing an internal, serine-rich, repetitive motif, Journal of Biological Chemistry, 272, (46), 1997, p29212 - 29221Journal Article, 1997, DOI
• Abdel-Latif MM, Windle H, Terres A, Eidhin DN, Kelleher D, Reynolds JV., Helicobacter pylori Extract Induces Nuclear Factor-kappa B, Activator Protein-1, and Cyclooxygenase-2 in Esophageal Epithelial Cells., J Gastrointest Surg. , 10, (4), 2006, p551 - 562Journal Article, 2006
• Windle HJ, Kelleher D, Crabtree JE, Childhood Helicobacter pylori infection and growth impairment in developing countries: a vicious cycle?, Pediatrics, 119, (3), 2007, p754 - 759Journal Article, 2007, DOI , TARA - Full Text
• Cornally D, Mee B, MacDonaill C, Tipton KF, Kelleher D, Windle HJ, Henehan G, Aldo-Keto Reductase from Helicobacter pylori: role in adaptation to growth at acid pH, FEBS J, 275, (12), 2008, p3041 - 3050Journal Article, 2008
• Mullaney E, Brown PA, Smith S, Botting CH, Yamoka Y, Terres AM, Kelleher DP, Windle HJ, Proteomic and functional characterization of the outer membrane vesicles from the gastric pathogen Helicobacter pylori, Proteomics Clin Appl, 3, (7), 2009, p785 - 796Journal Article, 2009
• Ruiz Marquez JF, Radics G, Windle H, Serra HO, Simplicio AL, Kedziora K, Fallon PG, Kelleher DP, Gilmer GF, Design, Synthesis, and Pharmacological Effects of a Cyclization-activated Steroid Prodrug for Colon Targeting in Inflammatory Bowel Disease, Journal of Medicinal Chemistry, 52, (10), 2009, p3205 - 3211Journal Article, 2009, DOI
• Harris P, Villagran A, Serrano C, Torres J, Duarte I, Crabtree J, Windle HJ, Helicobacter pylori infection alters iron metabolism in Chilean children, 9th Venezuelan Congress of Microbiology, Valencia, Venezuela, 12-15 November 2008, 2008Conference Paper, 2008
• Villagran A, Serrano C, Torres J, Duarte I, Windle H, Crabtree J, Harris P., Alteraciones en el perfil serico de Hierro en ninos infectados por Helicobacter pylori, Gastroenterologia Latinoamericana, Chile, 2008, edited by Caffri C, Pino RQ , 19, 2008Meeting Abstract, 2008
• Villagran A., Serrano C., Torres J., Duarte I., Windle HJ., Crabtree JE. Harris PR , Gastric pH and its relationship with H. pylori infection and serum iron in children., World congress of paediatric gastroenterology, hepatology and nutrition., Iguassu Falls, Brazil, 16-20 Aug 2008, 2008Meeting Abstract, 2008
• Finn D., Hearty S, O'Kennedy R, Kelleher D, Windle H, Increased adhesion of H. pylori to laminin under iron reduced conditions., Gastroenterology, American Gastroenterology association, DDW, Washington, USA, 2007Meeting Abstract, 2007
• Smith SM, Mullaney E, Duggan SP, Windle HJ, O'Neill LA, Kelleher D. , Toll-like Receptor 2-dependent Chemokine Induction in Epithelial Cells by Lipopolysaccharide Contained in Helicobacter pylori Outer Membrane Vesicles, Gastroenterology, American Gastroenterology association, DDW, Chicago, USA, 2009Meeting Abstract, 2009
• Mullaney, EM, Botting, CH, Windle, HJ, Terres, AM, Kelleher, DP, Characterization of the Proteome of Helicobacter pylori Outer Membrane Vesicles, Gastroenterology , American Gastroenterology association, DDW, Los Angeles, USA, 2006, 130, (4), 2006Meeting Abstract, 2006
• Henry Windle, Ross McManus, Dermot Kelleher, A vaccine for Helicobacter pylori , 2002Patent, 2002
• Abdel-Latif MM, Windle HJ, Davies A, Volkov Y, Kelleher D., A new mechanism of gastric epithelial injury induced by acid exposure: the role of Egr-1 and ERK signaling pathways., Journal of Cellular Biochemistry, 108, 2009, p249 - 160Journal Article, 2009
• Windle HJ, Brown PA, Kelleher D, Proteomics of Bacterial Pathogenicity: therapeutic implications, Proteomics - Clinical Applications, 4, (2), 2010, p1-13Review, 2010
• Lee G, Cama V, Gilman RH, Cabrera L, Saito M, Checkley W; CONTENT Investigators (Kelleher D, Windle H, Crabtree J), Comparison of two types of epidemiological surveys aimed at collecting daily clinical symptoms in community-based longitudinal studies., Ann Epidemiol., 20, (2), 2010, p151 - 158Journal Article, 2010
• Redpath MB, Windle H, Nolan D, Pays E, Voorheis HP, Carrington M, ESAG11, a new VSG expression site-associated gene from Trypanosoma brucei., Molecular and biochemical parasitology, 111, (1), 2000, p223-228Journal Article, 2000, DOI
• Brown P, Smith S, Botting C, Kelleher D, Windle HJ, H. pylori outer membrane vesicles modulate proinflammatory and other signalling pathways in gastric and non-gastric cells , Helicobacter, Rotterdam, Netherlands, 15, (4), 2010, pp321 - 321Meeting Abstract, 2010
• Smith SM, Moran AP, Duggan S, Ahmed SE, Mohamed AS, Windle HJ, O'Neill L, and Kelleher D., Tribbles 3: A Novel Regulator of TLR2-Mediated Signaling in Response to Helicobacter pylori Lipopolysaccharide , Journal of Immunology, 186, (4), 2011, p2462 - 2471Journal Article, 2011, URL
• Ruiz JF, Kedziora K, Windle HJ, Kelleher DP, Gilmer JF., Investigation into drug release from colon-specific azoreductase-activated steroid prodrugs using in-vitro models., J. Pharm. Pharmacol., 63, (6), 2011, p806 - 816Journal Article, 2011
• Marquez Ruiz JF, Kedziora K, Keogh B, Maguire J, Reilly M, Windle HJ, Kelleher D, Gilmer JF, A double prodrug system for colon targeting of benzenesulfonamide COX-2 inhibitors, Bioorganic & Medicinal Chemistry Letters, 21, (22), 2011, p6636-6640Journal Article, 2011, DOI , URL , TARA - Full Text
• O'Riordan AA, Morales V, Mulligan L, Faheem N, *Windle HJ, *Kelleher D, Alkyl Hydroperoxide reductase: a candidate Helicobacter pylori vaccine, Vaccine, 30 , (26), 2012, p3876 - 3884Journal Article, 2012
• Marquez Ruiz JF, Kedziora K, O'Reilly M, Maguire J, Keogh B, Windle HJ, Kelleher D, Gilmer JF, Azo-reductase activated budesodine prodrugs for colon targeting, Bioorganic and Medicinal Chemistry Letters, 22, (24), 2012, p7573 - 7577Journal Article, 2012
• Gavin J, Ruiz JFM, Kedziora K, Windle HJ, Kelleher D, Gilmer JF, Structure requirements for anaerobe processing of azo compounds: implications for prodrug design, Biooranic and Medicinal Chemistry Letters, 22 , (24), 2012, p7647 - 7652Journal Article, 2012
• Harris PR, Serrano CA, Villagrán A, Malker MM, Thomson M, Duarte I, Windle HJ, Crabtree JE , Helicobacter pylori-associated hypochlorohydria in children relates to the development of iron deficiency. , Journal of Clinical Pathology, 66, (4), 2013, p343 - 347Journal Article, 2013, DOI
• Marquez Ruiz JF, Kedziora K, Pigott M, Keogh B, Windle H, Gavin J, Kelleher DP, Gilmer JF., A nitrophenyl-based prodrug type for colorectal targeting of prednisolone, budesonide and celecoxib., Bioorg Med Chem Lett, 23, (6), 2013, p1693-8Journal Article, 2013, DOI
• Gavin J, Ruiz JF, Kedziora K, Windle H, Kelleher DP, Gilmer JF., Structure requirements for anaerobe processing of azo compounds: implications for prodrug design., Bioorganic and Medicinal Chemistry Letters, 22, (24), 2013, p7647-7652Journal Article, 2013, DOI
• Sing A, Windle HJ, Cornally D, Ryan B, Henehan GT., A Short-Chain NAD(H)-Dependent Alcohol dehydrogenase (HpSCADH) from Helicobactor pylori: A role in growth under neutral and acidic conditions., The International Journal of Biochemistry & Cell Biology, 45, (7), 2013, p1347-1355Journal Article, 2013
• Queiroz DMM, Harris PR, Sanderson IR, Windle HJ, Walker MM, Rocha AMC, Rocha GA, Carvalho SD, Bittencourt PFS, de Castro LPF, Cillagran A, Serrano C, Kelleher D, Crabtree JE, Iron status and Helicobacter pylori infection in children: an international multi-centered study , PlosOne, 8, (7), 2013, pe6883-Journal Article, 2013
• Queiroz, D.M.M., Harris, P.R., Sanderson, I.R., Windle, H.J., Walker, M.M., Rocha, A.M.C., Rocha, G.A., (...), Crabtree, J.E, Iron Status and Helicobacter pylori Infection in Symptomatic Children: An International Multi-Centered Study, PLoS ONE , 8, (7), 2013, art. no. e68833Journal Article, 2013, DOI , TARA - Full Text
• O'Riordan AA, Morales VA, Mulligan L, Faheem N, Windle HJ, Kelleher DP, Alkyl hydroperoxide reductase: a candidate Helicobacter pylori vaccine., Vaccine, 30, (26), 2012, p3876-84Journal Article, 2012, DOI
• Ruiz JF, Kedziora K, Keogh B, Maguire J, Reilly M, Windle H, Kelleher DP, Gilmer JF, A double prodrug system for colon targeting of benzenesulfonamide COX-2 inhibitors., Bioorganic & medicinal chemistry letters, 21, (22), 2011, p6636-40Journal Article, 2011, DOI
• Ruiz JF, Kedziora K, Windle H, Kelleher DP, Gilmer JF, Investigation into drug release from colon-specific azoreductase-activated steroid prodrugs using in-vitro models., The Journal of pharmacy and pharmacology, 63, (6), 2011, p806-816Journal Article, 2011, DOI
• Smith SM, Moran AP, Duggan SP, Ahmed SE, Mohamed AS, Windle HJ, O'Neill LA, Kelleher DP, Tribbles 3: a novel regulator of TLR2-mediated signaling in response to Helicobacter pylori lipopolysaccharide., Journal of immunology (Baltimore, Md. : 1950), 186, (4), 2011, p2462-2671Journal Article, 2011, DOI
• Saito M, Goel-Apaza S, Espetia S, Velasquez D, Cabrera L, Loli S, Crabtree JE, Black RE, Kosek M, Checkley W, Zimic M, Bern C, Cama V, Gilman RH; The Norovirus Working Group in Peru (Xiao L, Kelleher D, Windle HJ, van Doorn LJ, Varela M, Verastegui M, Calderon M, Alva A, Roman K), Multiple norovirus infections in a birth cohort in a Peruvian peri-urban community., Clin Infect Dis. , 58, (4), 2014, p483 - 491Journal Article, 2014, DOI , TARA - Full Text
• L.E. Collins, M Lynch, I Marszalowska, M. Kristek, K. Rochfort, M. O'Connell, H.J. Windle, D. Kelleher, C.E. Loscher, Surface layer proteins isolated from Clostridium difficile induce clearance responses in macrophages, Microbes and Infection, 2014Journal Article, 2014, DOI , TARA - Full Text
• D Jaganath, M Saito, RH Gilman, V Cama, L Cabrera, D Kelleher, H Windle, J Crabtree, W Checkley, First detected Helicobacter pylori infection in infancy modifies the association between diarrheal disease and childhood growth in Peru, Helicobacter, 2014Journal Article, 2014, TARA - Full Text

Infectious pathogens: Helicobacter pylori, Fusobacterium nucleatum, Campylobacter showae, Clostridium difficile

• Title

  Evaluation and Control of Neglected Mucosal Enteric Infections in Childhood
  Summary

  Microbial enteric pathogens are a major cause of childhood morbidity world-wide, contributing to impaired growth and cognitive function. In developing countries the diversity of childhood enteric infections makes diagnosis and disease surveillance difficult. To date there has been limited data on the impact of the major childhood infection Helicobacter pylori on global health issues in children in underdeveloped regions of the world. Initial infection with H. pylori is associated with a period of hypochlorhydria (reduced acid secretion), which we hypothesise is critical for the aquistion of other enteric infections, diarrhoeal disease and impaired childhood growth. In addition, we hypothesise that gastric H. pylori infection is a contributory factor to iron deficiency anaemia in childhood. The objective of the CONTENT project is to improve knowledge and apply new technologies to improve the control of neglected enteric pathogens in socio-economically disadvantaged childhood populations of Latin America
  Funding Agency

  European Union
  Date From

  2006
  Date To

  2010
• Title

  Evaluation of the carcinogenic potential of Fusobacterium nucleatum
  Summary

  Identification of the constituent bacterial species of the intestinal microbiota under normal and disease conditions has led to the identification of associations between dysbiosis and several chronic disease states. In this regard, an association between the bacterium Fusobacterium nucleatum and intestinal cancer has been identified. Originally this organism was identified as an oral pathogen responsible in part for periodontitis but now is found to be significantly associated with several extraoral dieases, including colon cancer. Interestingly, this pathogen is also enriched at sites of adenoma formation, the precursors of carcinoma, suggesting that it may be a primary initiator of carcinogenesis. Although causality has not yet been established there is compelling evidence indicating a primary role for this pathogen in disease progression. This project aims to investigate the pathogenic/carcinogenic potential of F. nucleatum using in vitro models by evaluating its ability to induce a pro-inflammatory environment and modulate/subvert cellular signalling pathways.
  Funding Agency

  Dept of Education, Government of Saudi Arabia
  Date From

  2013
  Date To

  2016
• Title

  Development of a Helicobacter pylori vaccine
  Summary
  Funding Agency

  Enterprise Ireland
  Date From

  2009
  Date To

  2010
• Title

  Development of Clostridium difficile vaccine
  Summary
  Funding Agency

  Enterprise Ireland
  Date From

  2002
  Date To

  2005

• Biochemical Society

• Member, Cycle 2 PI's & Researchers, All Cycle 2 Researchers & PI's
• Member, Centre for Research into Global Disease (Proposed), This consortium combines researchers with complementary interests in globally significant infectious disease. Interests include innate immunity, immune regulation, regional immunity, immune evasiob, vaccine & adjuvant development as well as drug & target development.
• Member, DMMC Inflammation, Immunity & Infection Principal Investigators, DMMC Principal Investigators leading research in inflammation, immunit and infection.