Medicine

Contact Us School of Medicine
Level 1
Trinity Biomedical Sciences Institute
Trinity College
152-160 Pearse Street
Dublin 2

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medadmin@tcd.ie
Dr. Michelle Armstrong

Dr. Michelle Armstrong

Assistant Professor, Clinical Medicine


Publications and Further Research Outputs

  • Mawhinney L, Armstrong ME, O' Reilly C, Bucala R, Leng L, Fingerle-Rowson G, Fayne D, Keane MP, Tynan A, Maher L, Cooke G, Lloyd D, Conroy H, Donnelly SC, Macrophage migration inhibitory factor (MIF) enzymatic activity and lung cancer., Molecular medicine, 20, (1), 2014, p729 - 735Journal Article, 2014
  • O'Dwyer DN, Armstrong ME, Kooblall M, Donnelly SC, Targeting defective Toll-like receptor-3 function and idiopathic pulmonary fibrosis., Expert Opin Ther Targets ., 2015Journal Article, 2015
  • Cooke G, Govender P, Watson CJ, Armstrong ME, O'Dwyer DN, Keane MP, King R, Tynan A, Dunn M, Donnelly SC, Sarcoidosis, alveolar ß-actin and pulmonary fibrosis., QJM, 2013Journal Article, 2013
  • O'Dwyer DN, Armstrong ME, Cooke G, Dodd JD, Veale DJ, Donnelly SC, Rheumatoid Arthritis (RA) associated interstitial lung disease (ILD)., Eur J Intern Med., 2013Journal Article, 2013
  • Adamali H, Armstrong ME, McLaughlin AM, Cooke G, McKone E, Costello CM, Gallagher CG, Leng L, Baugh JA, Fingerle-Rowson G, Bucala RJ, McLoughlin P, Donnelly SC, Macrophage migration inhibitory factor enzymatic activity, lung inflammation, and cystic fibrosis., Am J Respir Crit Care Med., 186, (2), 2012, p162 - 169Journal Article, 2012
  • Cooke G, Armstrong ME, Donnelly SC, Macrophage migration inhibitory factor (MIF), enzymatic activity and the inflammatory response., BIOFACTORS, 2009Journal Article, 2009
  • Armstrong ME, Gantier M, Li L, Chung WY, McCann A, Baugh JA, Donnelly SC, Small interfering RNAs induce macrophage migration inhibitory factor production and proliferation in breast cancer cells via a double-stranded RNA-dependent protein kinase-dependent mechanism., J Immunol., 2008Journal Article, 2008
  • Tynan A, Mawhinney L, Armstrong ME, O'Reilly C, Kennedy S, Caraher E, Jülicher K, O'Dwyer D, Maher L, Schaffer K, Fabre A, McKone EF, Leng L, Bucala R, Bernhagen J, Cooke G, Donnelly SC., Macrophage migration inhibitory factor enhances Pseudomonas aeruginosa biofilm formation, potentially contributing to cystic fibrosis pathogenesis., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31, (11), 2017, p5102-5110Journal Article, 2017, DOI
  • Cooke G, Kamal I, Strengert M, Hams E, Mawhinney L, Tynan A, O' Reilly C, O' Dwyer DN, Kunkel SL, Knaus UG, Shields DC, Moller DR, Bowie AG, Fallon PG, Hogaboam CM, Armstrong ME, Donnelly SC., Toll-like receptor 3 L412F polymorphism promotes a persistent clinical phenotype in pulmonary sarcoidosis., QJM, 2018, p217-224Journal Article, 2018, URL , TARA - Full Text
  • Rea IM, McNerlan SE, Alexander DH, Armstrong ME., Blood pressure and TNF-" act synergistically to increase leucocyte CD11b adhesion molecule expression in the BELFAST study: implications for better blood pressure control in ageing., Age (Dordrecht, Netherlands), 35, (1), 2013, p197-205Journal Article, 2013, DOI
  • Lavelle EC, McNeela E, Armstrong ME, Leavy O, Higgins SC, Mills KH., Cholera toxin promotes the induction of regulatory T cells specific for bystander antigens by modulating dendritic cell activation., Journal of immunology (Baltimore, Md. : 1950), 171, (5), 2003, p2384-2392Journal Article, 2003, DOI
  • Armstrong ME, Alexander HD, Ritchie JL, McMillan SA, Rea IM., Age-related alterations in basal expression and in vitro, tumour necrosis factor alpha mediated, upregulation of CD11b., Gerontology, 47, (4), 2001, p180-185Journal Article, 2001, DOI
  • MIF and Pulmonary Disease in, The MIF Handbook (1st Edition; Editor: Richard Bucala), World Scientific Publishing Company., 2012, [Cooke G, Armstrong ME, Conroy H and Donnelly SC]Book Chapter, 2012
  • Doroudian M and O'Neill A, O'Reilly C, Tynan A, Mawhinney, L, McElroy AN, Webster SS, Macloughlin R, Volkov Y, Armstrong ME, O'Toole GA, Prina-Mello A, Donnelly SC., Aerosolized drug-loaded nanoparticles targeting migration inhibitory factors inhibit Pseudomonas aeruginosa induced inflammation and biofilm formation, Nanomedicine, 15, (30), 2020, p2933-2953Journal Article, 2020, DOI
  • McElroy AN, Invernizzi R, Laskowska JW, O'Neill A, Doroudian M, Moghoofei M, Mostafaei S, Li F, Przybylski AA, O'Dwyer DN, Bowie AG, Fallon PG, Maher TM, Hogaboam CM, Molyneaux PL, Hirani N, Armstrong ME, Donnelly SC., Candidate Role for Toll-like Receptor 3 L412F Polymorphism and Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis., American journal of respiratory and critical care medicine, 2022Journal Article, 2022, DOI
  • Mostafaei S, Kazemnejad A, Azimzadeh Jamalkandi S, Amirhashchi S, Donnelly SC, Armstrong ME, Doroudian M., Identification of Novel Genes in Human Airway Epithelial Cells associated with Chronic Obstructive Pulmonary Disease (COPD) using Machine-Based Learning Algorithms., Sci. Rep., 8, (1), 2018, p15775-Journal Article, 2018, URL
  • Mostafaei S, Vahidi Manesh P, Sadri Nahand J, Nesaei A, Sorayyayi S, Abasabadi F, Mirzaei H, Etemadi A, O' Neill A, Donnelly SC, Doroudian M, Armstrong ME, Moghoofei M., The role of Epstein-Barr virus-expressed genes in breast cancer development, The breast journal, 26, (11), 2020, p2323 - 2326Journal Article, 2020, URL
  • Moghoofei M, Mostafaei S, Kondori N, Armstrong ME, Babaei F., Bacterial and viral coinfection in idiopathic pulmonary fibrosis patients: the prevalence and possible role in disease progression, BMC Pulm Med ., 22, (1), 2022, p60 - 67Journal Article, 2022, URL
  • Vancheri C, Luppi F. , Editorial: Identifying the Risk of Acute Exacerbation in Idiopathic Pulmonary Fibrosis: A Step Forward., American Journal of Respiratory and Critical Care Medicine, 205, (5), 2022, p489 - 491.Journal Article, 2022, URL
  • Shin JJ, Fan W, Par-Young J, Piecychna M, Leng L, Israni-Winger K, Qing H, Gu J, Zhao H, Schulz WL, Unlu S, Kuster J, Young G, Liu J, Ko AI, Baeza Garcia A, Sauler M, Wisnewski AV, Young L, Orduña A, Wang A, Klementina O, Garcia AB, Hegyi P, Armstrong ME, Mitchell P, Ordiz DB, Garami A, Kang I, Bucala R., MIF is a Common Genetic Determinant of COVID-19 Symptomatic Infection and Severity., QJM the Quarterly Journal of Medicine, 116, (3), 2023, p205 - 212Journal Article, 2023, URL
  • Nano-Based Therapies for Acute and Chronic Lung Diseases in, editor(s)Ribeiro de Araujo, D., Carneiro-Ramos, M. , Biotechnology Applied to Inflammatory Diseases - Cellular Mechanisms and Nanomedicine, https://doi.org/10.1007/978-981-19-8342-9_12, Springer, Singapore, 2023, [Doroudian M, Armstrong ME, Donnelly SC.]Book Chapter, 2023
  • Moore C, Blumhagen RZ, Yang IV, Walts A. et al., Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis., American Journal of Respiratory and Critical Care Medicine, 200, (2), 2019, p199 - 208Journal Article, 2019
  • Dunbar H, Hawthorne IJ, Tunstead C, Armstrong ME, Donnelly SC, English K., Blockade of MIF biological activity ameliorates house dust mite-induced allergic airway inflammation in humanized MIF mice., The FASEB Journal , 37, 2023, pe23072-Journal Article, 2023
  • Armstrong ME, Lavelle EC, Loscher CE, Lynch MA, Mills KHG, Proinflammatory Responses in the Murine Brain after Intranasal Delivery of Cholera Toxin: Implications for the Use of AB Toxins as Adjuvants in Intranasal Vaccines, Journal of Infectious Diseases, 192, (9), 2005, p1628 - 1633Journal Article, 2005, DOI , URL , TARA - Full Text
  • Costelloe C, Watson M, Murphy A, McQuillan K, Loscher C, Armstrong ME,, IL-1F5 mediates anti-inflammatory activity in the brain through induction, J Neurochem, 105, (5), 2008, p1960-1969Journal Article, 2008, DOI , URL
  • Armstrong, M.E., Loscher, C.E., Lynch, M.A. and Mills, K.H.G., IL-1beta-dependent neurological effects of the whole cell pertussis vaccine: a role for IL-1-associated signalling components in vaccine reactogenicity, J. Neuroimmunol., 136, (1-2), 2003, p25 - 33Journal Article, 2003, DOI , URL
  • Lavelle EC, Jarnicki A, McNeela E, Armstrong ME, Higgins SC, Leavy O, Mills KHG, Effects of cholera toxin on innate and adaptive immunity and its application as an immunomodulatory agent, Journal of Leukocyte Biology, 75, (5), 2004, p756 - 763Journal Article, 2004, DOI , TARA - Full Text
  • Hams E, Armstrong ME, Barlow JL, Saunders SP, Schwartz C, Cooke G, Fahy RJ, Crotty TB, Hirani N, Flynn RJ, Voehringer D, McKenzie AN, Donnelly SC, Fallon PG, IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis., Proceedings of the National Academy of Sciences of the United States of America, 111, (1), 2014, p367-72Journal Article, 2014, DOI , TARA - Full Text
  • O'Dwyer DN, Armstrong ME, Trujillo G, Cooke G, Keane MP, Fallon PG, Simpson AJ, Millar AB, McGrath EE, Whyte MK, Hirani N, Hogaboam CM, Donnelly SC., The Toll-like receptor 3 L412F polymorphism and disease progression in idiopathic pulmonary fibrosis., Am J Respir Crit Care Med., 188, 2013, p1442 - 1450Journal Article, 2013, DOI