Skip to main content

Trinity College Dublin, The University of Dublin

Trinity Menu Trinity Search



Dr. Adriele Prina Mello
Ussher Assistant Professor, Clinical Medicine

Biography

Adriele Prina-Mello, PhD, is an Ussher Assistant Professor in Translational Nanomedicine, Department of Clinical Medicine at the Trinity Translational Medicine Institute, School of Medicine. AMBER centre Investigator, CRANN Principal Investigator at Trinity College, Dublin. Chair of the working group in Characterization and Toxicology at the European Technology Platform for Nanomedicine. Expert Member of Nanosafety cluster, the EC Task Force in Characterization and European Materials Characterisation Council. Founder and Director of the Laboratory for Biological Characterization of Advanced Materials, the Irish-branch of the European Nanomedicine Characterization Laboratory (EU-NCL), the flagship infrastructure project funded by the European Commission, in partnership with the US-National Cancer Institute Nano Characterization Laboratory)for enabling Translational Nanomedicine. My objective is to drive LBCAM to become a core nanomedicine enabling infrastructure for educational training (e.g., undergraduates, postgraduates) and international collaboration with academia, industry, clinicians and public bodies. Prina-Mello's research interests are focused on the translation of nanotechnology-enabled products (e.g., medical device, medicinal drugs, hybrid products such as theranostics); advanced materials and their multifunctional solutions; device and instrumentation applications into the medical research area as Nanomedicine tools with the potential to become next generation medical standards or standards of care. The key Nanomedicine areas of interest where I have developed expertise are: 1)Nanodiagnostics: advanced in vitro/ in vivo diagnostic and imaging devices and instrumentation. 2) Theranostics and Personalised Medicine: therapeutics based on nanotechnology and multilayered structures for localised and personalised medicine. 3) Regenerative Medicine: biomedical devices and nanotechnology and nanomaterials applied to tissue engineering. 4) Nanocharacterization and Safety: safe-by-design, responsible innovation development and regulatory compliance. Credited with more than 70 peer-review publications, 6 book chapters, 2 Booklets (as editor), 2 Special Issue (as topic editor), 7 invited scientific reviews, > 25 invited lectures, >50 conference proceedings, >100 posters. (all indexed in Google Scholars, Research Gate, or RSS, April 2016) Contributed to educational and learning by lecturing undergraduate students in Medicine and postgraduate Master degrees in Molecular Medicine, Translational Oncology, Pharmaceutical Science. Since 2010 provided mentoring, educational training, and transferable skills to more than 15 students who are now accomplished professionals. Prina-Mello's scientific and teaching international collaborators are the results of the extensive European Commission involvement and research projects activity. Prina-Mello is an active member at TCD of the following: Trinity Cancer committee, AMBER/CRANN Environmental, Health, and Safety (EHS) platform, the TTMI TARGET Radiobiology group, the TTMI outreach committee, the TTMI Health and Safety, the Translational Child Health and Paediatrics forum, the St. James's Intensive Care Unit research group.

Publications and Further Research Outputs

Peer-Reviewed Publications

Costanza Di Marco, Sarah Kennedy, Adriele Prina Mello, Evaluating an ECM-Mimetic Basement Membrane as a Modulator of Cellular and Microbial Dynamics in Chronic Wounds, Dublin Academy of Pathogenomics & Infection Biology Group, Trinity College Dublin, Ireland, 5th June 2026, 2026 Conference Output, 2026 URL

Heeran Aisling B, Hannon Gary, Moran Barry, Ui Mhaonaigh Aisling, Passos Valeria Lima, Menon Meghana, Bhardwaj Anshul, Ravi Narayanasamy, Reynolds John, Prina-Mello Adriele, O'Sullivan Jacintha, Marcone Simone, Serum and adipose tissue-derived extracellular vesicles as biomarker reservoirs in oesophageal adenocarcinoma, Scientific Reports, 2026 Journal Article, 2026 URL DOI

Gabriele Vella, Martin P. Barr, Anne-Marie Baird, Adriele Prina-Mello, Dania Movia, Testing EV-Based Therapeutic Strategies in Physiologically Relevant In Vitro Lung Adenocarcinoma Models, The Irish Society for Gene and Cell Therapy (ISGCT) Conference, Galway, 22"23 Jan 2026, 2026 Poster, 2026 URL

Hackett David, Kane Laura E, Prina-Mello Adriele, Maher Stephen G, Current and emerging strategies to enhance chemotherapeutic efficacy in pancreatic ductal adenocarcinoma, BMC Medicine, 2026 Review Article, 2026 URL DOI

Anne R. Kinsella, Adriele Prina-Mello, Laure Marignol, Evaluation of the association between sex-linked genes and treatment response in lung cancer, Radiotherapy and Oncology, 212, 2025, p111159 - 111159, p111159-111159 Journal Article, 2025 DOI

Melissa Anne Tutty, Tecla Simone, Adriele Prina-Mello, Development of a complex 3D in vitro alternative model to evaluate the safety of advanced materials, Toxicology and Applied Pharmacology, 504, 2025, p117520 - 117520, p117520-117520 Journal Article, 2025 DOI

Zamira V. Díaz-Riascos, Monserrat Llaguno-Munive, Nuria Lafuente-Gómez, Yurena Luengo, Sarah J. Holmes, Jeanne Volatron, Oihane Ibarrola, Sandra Mancilla, Francesca Sarno, José Javier Aguirre, Sarah Razafindrakoto, Paul Southern, Francisco J. Terán, Anna Keogh, Gorka Salas, Adriele Prina-Mello, Juan Carlos Lacal, Ángel del Pozo, Quentin A. Pankhurst, Manuel Hidalgo, Florence Gazeau, Álvaro Somoza, Simó Schwartz, Ibane Abasolo, Preclinical Development of Magnetic Nanoparticles for Hyperthermia Treatment of Pancreatic Cancer, ACS Applied Materials & Interfaces, 17, (2), 2025, p2924 - 2939, p2924-2939 Journal Article, 2025 DOI

Moen, A. and Johnsen, H. and Hristozov, D. and Zabeo, A. and Pizzol, L. and Ibarrola, O. and Hannon, G. and Holmes, S. and Debebe Zegeye, F. and Vogel, U. and Prina Mello, A. and Zienolddiny-Narui, S. and Wallin, H., Inflammation related to inhalation of nano and micron sized iron oxides: a systematic review, Nanotoxicology, 2024 Review, 2024 DOI

Gary Hannon, Bethany J. Heaton, Alexander J. Plant-Hately, Christopher David, Neill J. Liptrott, Ainhoa Egizabal, Ana Ayerdi-Izquierdo, Noelia Álvarez, Oihane Ibarrola, Andres Arbona Celaya, Alberto Pérez, Nerea Lazcanoiturburu, Iris Luzuriagaf, Fikirte Debebe Zegeye, Shanbeh Zienolddiny, An Jacobs, Alexandra Van Driessche, Inge Nelissen, Ibane Abasolo, Fernanda Andrade, Nora Ventosa, Elisabet González-Mira, Aida Carreño, Adriele Prina-Mello, Interlaboratory comparison of endotoxin contamination assessment of nanomaterials, Nanoscale, 2024 Journal Article, 2024 DOI

Melissa Anne Tutty, Adriele Prina-Mello, Multilineage 3D Hepatic Spheroids as a Complex Model for the Pre-Clinical Assessment of NanoBioMaterials (NBMs). Selected, IACR-EACR-IACR Basic and Translational Research Conference., Dublin Convention centre, Dublin, Ireland, 27-29 Febr 2024, 2024 Poster, 2024

Fanny Caputo, Georges Favre, Gerrit Borchard, Luigi Calzolai, Paola Fisicaro, Emeric Frejafon, Nazende Günday-Türeli, Denis Koltsov, Caterina Minelli, Bryant C Nelson, Jérémie Parot, Adriele Prina-Mello, Shan Zou, François-Xavier Ouf, Toward an international standardisation roadmap for nanomedicine, Drug Delivery and Translational Research, 14, (9), 2024, p2578-2588 Review Article, 2024 DOI

Maitiú Ó Murchú, Xuehua Lin, Melissa Anne Tutty, Christina Cahill, Ian S. Miller, Lasse Jensen, Adriele Prina-Mello, Niamh Lynam-Lennon, Stephen G. Maher, Helena Kelly, Jacintha O'Sullivan, Enhancing cancer radiotherapy efficacy using NanOx, a novel oxygenating perfluorocarbon nanoemulsion that reverses tumour hypoxia., Cancer Letters, 2024, p217406 - 217406, p217406-217406 Journal Article, 2024 DOI

. J. Huber, A. M. Booth, I. Beer, I. Bianchi, R. Drexel, O. Geiss, D. Mehn, F. Meier, A. Molska, J. Parot, L. Sørensen, G. Vella, A. Prina-Mello, R. Vogel, F. Caputo, N. P. Ivleva, Inter-comparison of Different Fractionation and Batch Methods for the Physicochemical Characterization and Quantification of Nanoplastics, 23rd International Symposium on Field- and Flow-based Separations, Cité des Congrès in the heart of Nantes, France, 3-6 Jun 2024, 2024 Conference Paper, 2024 URL

Simone Marcone, Jolanda Spadavecchia, Memona Khan, Gabriele Vella, Fiona O'Connell, Marzia Pendino, Meghana Menon, Claire Donohoe, Narayanasamy Ravi, John V. Reynolds, Stephen G. Maher, Niamh Lynam-Lennon, Breandán N. Kennedy, Adriele Prina-Mello, Jacintha O'Sullivan, Targeting Radiation Resistance in Oesophageal Adenocarcinoma with Pyrazinib-Functionalised Gold Nanoparticles, Cancers, 16, (23), 2024, p4007 - 4007, p4007-4007 Journal Article, 2024 DOI

Ripoll-Viladomiu, I. and Prina-Mello, A. and Movia, D. and Marignol, L., Extracellular vesicles and the "six Rs" in radiotherapy, Cancer Treatment Reviews, 129, (102799), 2024 Review Article, 2024 DOI

Jeremie Parot, Dora Mehn, Hanna Jankevics, Natalia Markova, Michele Carboni, Camilla Olaisen, Andrea D Hoel, Margret S Sigfusdottir, Florian Meier, Roland Drexel, Gabriele Vella, Birgitte McDonagh, Terkel Hansen, Huong Bui, Geir Klinkenberg, Torkild Visnes, Sabrina Gioria, Patricia Urban-Lopez, Adriele Prina-Mello, Sven Even Borgos, Fanny Caputo, Luigi Calzolai, Quality assessment of LNP-RNA therapeutics with orthogonal analytical techniques, Journal of Controlled Release, 367, 2024, p385-401 Journal Article, 2024 DOI

Soliman, M.G. and Trinh, D.N. and Ravagli, C. and Meleady, P. and Henry, M. and Movia, D. and Doumett, S. and Cappiello, L. and Prina-Mello, A. and Baldi, G. and Monopoli, M.P., Development of a fast and simple method for the isolation of superparamagnetic iron oxide nanoparticles protein corona from protein-rich matrices, Journal of Colloid and Interface Science, 659, 2024, p503-519 Journal Article, 2024 DOI

A Method for the In Vitro Cytotoxicity Assessment of Anti-cancer Compounds and Materials Using High Content Screening Analysis in, Cancer Cell Culture Methods and Protocols, 2023, pp241-249 , [Tutty, Melissa A. and Prina-Mello, Adriele] Book Chapter, 2023 DOI

Dania Movia and Adriele Prina-Mello*, Cancer Cell Culture Methods and Protocols, Methods in Molecular Biology, New York, Humana Press - Springer Nature, 2023, 1 - 2989pp Book, 2023 URL

The Basics and Two-Dimensional Cultures in, Cancer Cell Culture: Methods and Protocols, 2023, pp3-40 , [Tutty, M.A. and Holmes, S. and Prina-Mello, A.] Book Chapter, 2023 DOI

Huber, M.J. and Ivleva, N.P. and Booth, A.M. and Beer, I. and Bianchi, I. and Drexel, R. and Geiss, O. and Mehn, D. and Meier, F. and Molska, A. and Parot, J. and SÞrensen, L. and Vella, G. and Prina-Mello, A. and Vogel, R. and Caputo, F., Physicochemical characterization and quantification of nanoplastics: applicability, limitations and complementarity of batch and fractionation methods, Analytical and Bioanalytical Chemistry, 415, (15), 2023, p3007-3031 Journal Article, 2023 DOI

Hector Gonzalez, Sean McCarthy, Claire Masterson, Declan Byrnes, Ignacio Sallent, Emma Horan, Stephen J Elliman, Gabriele Vella, Adriele Prina-Mello, Johnatas D Silva, Anna D Krasnodembskaya, Ronan MacLoughlin, John G Laffey, Daniel O'Toole, Nebulised mesenchymal stem cell derived extracellular vesicles ameliorate E. coli induced pneumonia in a rodent model, Stem Cell Research & Therapy, 14, (1), 2023 Journal Article, 2023 DOI

A Method for Culturing 3D Tumoroids of Lung Adenocarcinoma Cells at the Air-Liquid Interface in, 2023, pp173-178 , [Movia, D. and Prina-Mello, A.] Book Chapter, 2023 DOI

Testing the Effects of Magnetic Hyperthermia in 2D Cell Culture in, Cancer Cell Culture Methods and Protocols, 2023, pp251-261 , [Hannon, G. and Prina-Mello, A.] Book Chapter, 2023 DOI

Three-Dimensional Spheroids for Cancer Research in, Cancer Cell Culture Methods and Protocols, 2023, pp65-103 , [Tutty, Melissa A. and Prina-Mello, Adriele] Book Chapter, 2023 DOI

Hannon, G. and Bogdanska, A. and Keogh, A. and Finn, S.P. and Gobbo, O.L. and Prina-Mello, A., Biodistribution and histological analysis of iron oxide-dextran nanoparticles in wistar rats, Nanotoxicology, 17, (8-9), 2023, p562-580 Journal Article, 2023 DOI

Spring, K. and Weltring, K.-M. and Prina-Mello, A. and Schmid, R., REFINE special issue, Drug Delivery and Translational Research, 12, (9), 2022, p2039-2041 Journal Article, 2022 DOI

Galligioni, V. and Movia, D. and Ruiz-Perez, D. and Sanchez-Morgado, J.M. and Prina-Mello, A., The Case for Modernizing Biomedical Research in Ireland through the Creation of An Irish 3Rs Centre, Animals, 12, (9), 2022 Journal Article, 2022 DOI

Powell, L.G. and Gillies, S. and Fernandes, T.F. and Murphy, F. and Giubilato, E. and Cazzagon, V. and Hristozov, D. and Pizzol, L. and Blosi, M. and Costa, A.L. and Prina-Mello, A. and Bouwmeester, H. and Sarimveis, H. and Janer, G. and Stone, V., Developing Integrated Approaches for Testing and Assessment (IATAs) in order to support nanomaterial safety, Nanotoxicology, 2022 Journal Article, 2022 DOI

Adriele Prina-Mello, NanoInnovation Conference and Exhibition 2022, 18-23 Sep 2022, 2022, University of Rome, La Sapienza, Rome, Italy Meetings /Conferences Organised, 2022

Fernandez, Y. and Movellan, J. and Foradada, L. and Gimenez, V. and Garcia-Aranda, N. and Mancilla, S. and Arminan, A. and Borgos, S.E. and Hyldbakk, A. and Bogdanska, A. and Gobbo, O.L. and Prina-Mello, A. and Ponti, J. and Calzolai, L. and Zagorodko, O. and Gallon, E. and Nino-Pariente, A. and Paul, A. and Schwartz Jr, S. and Abasolo, I. and Vicent, M.J., In Vivo Antitumor and Antimetastatic Efficacy of a Polyacetal-Based Paclitaxel Conjugate for Prostate Cancer Therapy, Advanced Healthcare Materials, 11, (7), 2022 Journal Article, 2022 DOI

Silvia Pisani, Giulia Bertino, Adriele Prina-Mello, Laura Deborah Locati, Simone Mauramati, Ida Genta, Rossella Dorati, Bice Conti, Marco Benazzo, Electroporation in Head-and-Neck Cancer: An Innovative Approach with Immunotherapy and Nanotechnology Combination, Cancers, 2022 Journal Article, 2022 DOI

Bastogne, T. and Caputo, F. and Prina-Mello, A. and Borgos, S. and Barberi-Heyob, M., A state of the art in analytical quality-by-design and perspectives in characterization of nano-enabled medicinal products, Journal of Pharmaceutical and Biomedical Analysis, 219, (114911), 2022 Journal Article, 2022 DOI

Melissa Anne Tutty, Gabriele Vella, Antje Vennemann, Martin Wiemann, Adriele Prina-Mello, Evaluating nanobiomaterial-induced DNA strand breaks using the alkaline comet assay, Drug Delivery and Translational Research, 2022 Journal Article, 2022 DOI

Tutty, M.A. and Movia, D. and Prina-Mello, A., Three-dimensional (3D) liver cell models - a tool for bridging the gap between animal studies and clinical trials when screening liver accumulation and toxicity of nanobiomaterials, Drug Delivery and Translational Research, 2022 Review Article, 2022 DOI

Caterina Minelli, Magdalena Wywijas, Dorota Bartczak, Susana Cuello-Nuñez, Heidi Goenaga Infante, Jerome Deumer, Christian Gollwitzer, Michael Krumrey, Karen E Murphy, Monique E Johnson, Antonio R Montoro Bustos, Ingo H Strenge, Bertrand Faure, Peter Høghøj, Vivian Tong, Loïc Burr, Karin Norling, Fredrik Höök, Matthias Roesslein, Jovana Kocic, Lyndsey Hendriks, Vikram Kestens, Yannic Ramaye, Maria C Contreras Lopez, Guy Auclair, Dora Mehn, Douglas Gilliland, Annegret Potthoff, Kathrin Oelschlägel, Jutta Tentschert, Harald Jungnickel, Benjamin C Krause, Yves U Hachenberger, Philipp Reichardt, Andreas Luch, Thomas E Whittaker, Molly M Stevens, Shalini Gupta, Akash Singh, Fang-hsin Lin, Yi-Hung Liu, Anna Luisa Costa, Carlo Baldisserri, Rid Jawad, Samir EL Andaloussi, Margaret N Holme, Tae Geol Lee, Minjeong Kwak, Jaeseok Kim, Johanna Ziebel, Cedric Guignard, Sebastien Cambier, Servane Contal, Arno C Gutleb, Jan "Kuba" Tatarkiewicz, Bart"omiej J Jankiewicz, Bartosz Bartosewicz, Xiaochun Wu, Jeffrey A Fagan, Elisabeth Elje, Elise Runden-Pran, Maria Dusinska, Inder Preet Kaur, David Price, Ian Nesbitt, Ruud JB Peters, Guillaume Bucher, Dennis Coleman, Angela J Harrison, Antoine Ghanem, Anne Gering, Eileen McCarron, Niamh Fitzgerald, Geert Cornelis, Jani Tuoriniemi, Midori Sakai, Hidehisa Tsuchida, Ciarán Maguire, Adriele Prina-Mello, Alan J Lawlor, Jessica Adams, Carolin L Schultz, Doru Constantin, Nguyen Thi Kim Thanh, Le Duc Tung, Luca Panariello, Spyridon Damilos, Asterios Gavriilidis, Iseult Lynch, Benjamin Fryer, Ana Carrazco Quevedo, Emily Guggenheim, Sophie Briffa, Eugenia Valsami-Jones, Yuxiong Huang, Arturo A Keller, Virva-Tuuli Kinnunen, Siiri Perämäki, Zeljka Krpetic, Michael Greenwood, Alexander G Shard, Versailles project on advanced materials and standards (VAMAS) interlaboratory study on measuring the number concentration of colloidal gold nanoparticles, Nanoscale, 14, (12), 2022, p4690-4704 Journal Article, 2022 DOI

Gary Hannon and Adriele Prina-Mello, Safety and Efficacy Assessment of Iron Oxide Nanoparticles intended for Magnetic Hyperthermia: A Translational Story, Magnetic Carrier Meeting, University College London, UK, 14th Jun 2022, 2022 Oral Presentation, 2022 URL

Halamoda-Kenzaoui, B. and Geertsma, R. and Pouw, J. and Prina-Mello, A. and Carrer, M. and Roesslein, M. and Sips, A. and Weltring, K.M. and Spring, K. and Bremer-Hoffmann, S., Future perspectives for advancing regulatory science of nanotechnology-enabled health products, Drug Delivery and Translational Research, 12, (9), 2022, p2145-2156 Journal Article, 2022 DOI

Melissa Anne Tutty, Gabriele Vella, Adriele Prina-Mello, Pre-clinical 2D and 3D toxicity response to a panel of nanomaterials; comparative assessment of NBM-induced liver toxicity, Drug Delivery and Translational Research, 2022 Journal Article, 2022 DOI

Neuhaus W, Reininger-Gutmann B, Rinner B, Plasenzotti R, Wilflingseder D, De Kock J, Vanhaecke T, Rogiers V, Jírová D, Kejlová K, Knudsen LE, Nielsen RN, Kleuser B, Kral V, Thöne-Reineke C, Hartung T, Pallocca G, Leist M, Hippenstiel S, Lang A, Retter I, Krämer S, Jedlicka P, Ameli K, Fritsche E, Tigges J, Buettner M, Bleich A, Baumgart N, Baumgart J, Meinhardt MW, Spanagel R, Chourbaji S, Kränzlin B, Seeger B, von Köckritz-Blickwede M, Sánchez-Morgado JM, Galligioni V, Ruiz-Pérez D, Movia D, Prina-Mello A, Ahluwalia A, Chiono V, Gutleb AC, Schmit M, van Golen B, van Weereld L, Kienhuis A, van Oort E, van der Valk J, Smith A, Roszak J, St"pnik M, Soba"ska Z, Olsson IAS, Franco NH, Sevastre B, Kandarova H, Capdevila S, Johansson J, Cederroth CR, Sandström J, Ragan I, Bubalo N, Spielmann H., The Rise of Three Rs Centres and Platforms in Europe., Alternatives to laboratory animals : ATLA, 50, (2), 2022, p90-120 Journal Article, 2022 DOI

Adriele Prina-Mello and REFINE organising committee, REFINE 3rd & last Knowledge Exchange Conference, 26-27 Jan 2022, 2022, e-conference (virtual) Meetings /Conferences Organised, 2022 URL

Farmer, W. and Hannon, G. and Ghosh, S. and Prina-Mello, A., Thermal ablation in pancreatic cancer: A scoping review of clinical studies, Frontiers in Oncology, 12, (1066990), 2022 Review, 2022 DOI

Montanha MC, Howarth A, Mohamed DA, Loier E, Main L, Rösslein M, Delmaar C, Prina-Mello A, Siccardi M, A Physiologically Based Pharmacokinetic Model to Predict Pegylated Liposomal Doxorubicin Disposition in Rats and Human, 2022 Journal Article, 2022 DOI

Neuhaus W, Reininger-Gutmann B, Rinner B, Plasenzotti R, Wilflingseder D, De Kock J, Vanhaecke T, Rogiers V, Jírová D, Kejlová K, Knudsen LE, Spielmann H, The Current Status and Work of Three Rs Centres and Platforms in Europe., Alternatives to laboratory animals : ATLA, 2022 Journal Article, 2022 DOI

Essa, N. and O'Connell, F. and Prina-Mello, A. and O'Sullivan, J. and Marcone, S., Gold nanoparticles and obese adipose tissue microenvironment in cancer treatment, Cancer Letters, 525, 2022, p1-8 Journal Article, 2022 DOI

Tutty, M.A. and Vella, G. and Vennemann, A. and Wiemann, M. and Prina-Mello, A., Correction: Evaluating nanobiomaterial-induced DNA strand breaks using the alkaline comet assay (Drug Delivery and Translational Research, (2022), 12, 9, (2243-2258), 10.1007/s13346-022-01178-7), Drug Delivery and Translational Research, 12, (9), 2022, p2259 Journal Article, 2022 DOI

Editorial: Use of 3D Models in Drug Development and Precision Medicine - Advances and Outlook Editorial Board, 2021 DOI

Caputo, F. and Vogel, R. and Savage, J. and Vella, G. and Law, A. and Della Camera, G. and Hannon, G. and Peacock, B. and Mehn, D. and Ponti, J. and Geiss, O. and Aubert, D. and Prina-Mello, A. and Calzolai, L., Measuring particle size distribution and mass concentration of nanoplastics and microplastics: addressing some analytical challenges in the sub-micron size range, Journal of Colloid and Interface Science, 588, 2021, p401-417 Journal Article, 2021 DOI TARA - Full Text

Caputo, F. and Mehn, D. and Clogston, J.D. and Roesslein, M. and Prina-Mello, A. and Borgos, S.E. and Gioria, S. and Calzolai, L., Asymmetric-flow field-flow fractionation for measuring particle size, drug loading and (in)stability of nanopharmaceuticals. The joint view of European Union Nanomedicine Characterization Laboratory and National Cancer Institute - Nanotechnology Characterization Laboratory, Journal of Chromatography A, 1635, (461767), 2021 Journal Article, 2021 DOI TARA - Full Text

Singh, B. and Abdelgawad, M.E. and Ali, Z. and Bailey, J. and Budyn, E. and Civita, P. and Clift, M.J.D. and Connelly, J.T. and Constant, S. and Hittinger, M. and Kandarova, H. and Kearns, V.R. and Kiuru, T. and Kostrzewski, T. and Kress, S. and Durban, V.M. and Lehr, C.-M. and McMillan, H. and Metz, J.K. and Monteban, V. and Movia, D. and Neto, C. and Owen, C. and Paasonen, L. and Palmer, K.A. and Pilkington, G.J. and Pilkington, K. and Prina-Mello, A. and Roper, C. and Sheard, J. and Smith, S. and Turner, J.E. and Roy, I. and Tutty, M.A. and Velliou, E. and Wilkinson, J.M., Towards more predictive, physiological and animal-free in vitro models: Advances in cell and tissue culture 2020 conference proceedings, ATLA Alternatives to Laboratory Animals, 49, (3), 2021, p93-110 Journal Article, 2021 DOI

Doroudian, M. and O†Neill, A. and Mac Loughlin, R. and Prina-Mello, A. and Volkov, Y. and Donnelly, S.C., Nanotechnology in pulmonary medicine, Current Opinion in Pharmacology, 56, 2021, p85-92 Journal Article, 2021 DOI TARA - Full Text

Vogel, R. and Savage, J. and Muzard, J. and Camera, G.D. and Vella, G. and Law, A. and Marchioni, M. and Mehn, D. and Geiss, O. and Peacock, B. and Aubert, D. and Calzolai, L. and Caputo, F. and Prina-Mello, A., Measuring particle concentration of multimodal synthetic reference materials and extracellular vesicles with orthogonal techniques: Who is up to the challenge?, Journal of Extracellular Vesicles, 10, (3), 2021 Journal Article, 2021 TARA - Full Text DOI

Hannon, Gary, Prina-Mello, Adriele, Endotoxin contamination of engineered nanomaterials: Overcoming the hurdles associated with endotoxin testing, WIREs Nanomedicine and Nanobiotechnology, 2021 Review Article, 2021 DOI

Prina-Mello A, Bonacina L, Staedler D, Movia D, Editorial: Use of 3D Models in Drug Development and Precision Medicine - Advances and Outlook., Frontiers in bioengineering and biotechnology, 2021 Journal Article, 2021 DOI

Bogdanska, A. and Gobbo, O.L. and Volkov, Y. and Prina-Mello, A., 3D volume segmentation and reconstruction. Supervised image classification and automated quantification of superparamagnetic iron oxide nanoparticles in histology slides for safety assessment, Nanotoxicology, 15, (9), 2021, p1151-1167 Journal Article, 2021 DOI

Hannon, Gary, Tansi, Felista L., Hilger, Ingrid, Prina-Mello, Adriele, The Effects of Localized Heat on the Hallmarks of Cancer, Advanced Therapeutics, 4, (7), 2021, p2000267 Review Article, 2021 DOI

Nanomed Europe organising committee, NanoMed Europe 2021 - ETPN annual event, 7 Sep 2021, 2021, e-conference online (virtual) Meetings /Conferences Organised, 2021

Pisani, S. and Dorati, R. and Genta, I. and Benazzo, M. and Conti, B. and Prina Mello, A., A study focused on macrophages modulation induced by the Polymeric Electrospun Matrices (EL-Ms) for application in tissue regeneration: In vitro proof of concept, International Journal of Pharmaceutics, 603, (120712), 2021 Journal Article, 2021 DOI

Pisani, P. and Airoldi, M. and Allais, A. and Valletti, P.A. and Battista, M. and Benazzo, M. and Briatore, R. and Cacciola, S. and Cocuzza, S. and Colombo, A. and Conti, B. and Costanzo, A. and della Vecchia, L. and Denaro, N. and Fantozzi, C. and Galizia, D. and Garzaro, M. and Genta, I. and Iasi, G.A. and Krengli, M. and Landolfo, V. and Lanza, G.V. and Magnano, M. and Mancuso, M. and Maroldi, R. and Masini, L. and Merlano, M.C. and Piemonte, M. and Pisani, S. and Prina-Mello, A. and Prioglio, L. and Rugiu, M.G. and Scasso, F. and Serra, A. and Valente, G. and Zannetti, M. and Zigliani, A., Metastatic disease in head & neck oncology [La malattia metastatica in oncologia testa-collo], Acta Otorhinolaryngologica Italica, 40, (2), 2020, pS1-S86 Journal Article, 2020 DOI TARA - Full Text

Dania Movia, Maroua Benhaddada, Jolanda Spadavecchia, Adriele Prina-Mello, Latest advances in combining gold nanomaterials with physical stimuli towards new responsive therapeutic and diagnostic strategies , Precision Nanomedicine, 3, (2), 2020, p495 - 524 Review Article, 2020 DOI

Moloney M. Brian, Gilligan E. Katie, Joyce P. Doireann, O'Neill P. Clodagh, O'Brien P. Killian, Khan Sonja, Glynn L. Claire, Waldron M. Ronan, Maguire M. Ciaran, Holian Emma, Naughton Erin, Elhadi Mohamed, Grealish B. Andrea, Malone Carmel, McDermott Emma, Dockery Peter, Ritter Thomas, Prina-Mello Adriele, Kerin J. Michael, Dwyer M. Roisin, Investigating the Potential and Pitfalls of EV-Encapsulated MicroRNAs as Circulating Biomarkers of Breast Cancer, Cells, 9, (1), 2020 Journal Article, 2020 DOI TARA - Full Text

Movia D, Prina-Mello A., Preclinical Development of Orally Inhaled Drugs (OIDs)-Are Animal Models Predictive or Shall We Move Towards In Vitro Non-Animal Models?, Animals : an open access journal from MDPI, 10, (8), 2020 Review Article, 2020 TARA - Full Text DOI

Doroudian M and O'Neill A, O'Reilly C, Tynan A, Mawhinney, L, McElroy AN, Webster SS, Macloughlin R, Volkov Y, Armstrong ME, O'Toole GA, Prina-Mello A, Donnelly SC., Aerosolized drug-loaded nanoparticles targeting migration inhibitory factors inhibit Pseudomonas aeruginosa induced inflammation and biofilm formation, Nanomedicine, 15, (30), 2020, p2933-2953 Journal Article, 2020 DOI

Giuseppina Sandri, Angela Faccendini, Marysol Longo, Marco Ruggeri, Silvia Rossi, Maria Cristina Bonferoni, Dalila Miele, Adriele Prina-Mello, Carola Aguzzi, Cesar Viseras, Franca Ferrari, Halloysite- and Montmorillonite-Loaded Scaffolds as Enhancers of Chronic Wound Healing, Pharmaceutics, 12, (2), 2020, p179 Journal Article, 2020 TARA - Full Text DOI

Alberti Marco, Prina-Mello Adriele, Smart model of intrinsic loss power of SPIONs in hyperthermia treatment, Journal of Magnetism and Magnetic Materials, 502, 2020, p166493- Journal Article, 2020 DOI URL

Haddada MB, Movia D, Prina-Mello A, Spadavecchia J., Docetaxel gold complex nanoflowers: A chemo-biological evaluation for their use as nanotherapeutics., Colloids and surfaces. B, Biointerfaces, 194, 2020, p111172 Journal Article, 2020 DOI

Giubilato, E. and Cazzagon, V. and Amorim, M.J.B. and Blosi, M. and Bouillard, J. and Bouwmeester, H. and Costa, A.L. and Fadeel, B. and Fernandes, T.F. and Fito, C. and Hauser, M. and Marcomini, A. and Nowack, B. and Pizzol, L. and Powell, L. and Prina-Mello, A. and Sarimveis, H. and Scott-Fordsmand, J.J. and Semenzin, E. and Stahlmecke, B. and Stone, V. and Vignes, A. and Wilkins, T. and Zabeo, A. and Tran, L. and Hristozov, D., Risk management framework for nano-biomaterials used in medical devices and advanced therapy medicinal products, Materials, 13, (20), 2020, p1-29 Journal Article, 2020 DOI TARA - Full Text

Tereza Svadlakova, Frantisek Hubatka, Pavlina Turanek Knotigova, Pavel Kulich, Josef Masek, Jan Kotoucek, Jan Macak, Martin Motola, Martin Kalbac, Martina Kolackova, Radka Vankova, Petra Vicherkova, Andrea Malkova, Pavlina Simeckova, Yuri Volkov, Adriele Prina-Mello, Irena Kratochvilova, Zdenek Fiala, Milan Raska, Jan Krejsek, Jaroslav Turanek, Proinflammatory Effect of Carbon-Based Nanomaterials: In Vitro Study on Stimulation of Inflammasome NLRP3 via Destabilisation of Lysosomes, Nanomaterials, 10, (3), 2020 Journal Article, 2020 TARA - Full Text DOI

Hannon Gary, Bogdanska Anna, Volkov Yuri, Prina-Mello Adriele, Comparing the Effects of Intracellular and Extracellular Magnetic Hyperthermia on the Viability of BxPC-3 Cells, Nanomaterials, 10, (3), 2020 Journal Article, 2020 TARA - Full Text DOI

P. Pisani, M. Airoldi, A. Allais, P. Aluffi Valletti, M. Battista, M. Benazzo, R. Briatore, S. Cacciola, S. Cocuzza, A. Colombo, B. Conti, A. Costanzo, L. della Vecchia, N. Denaro, C. Fantozzi, D. Galizia, M. Garzaro, I. Genta, G.A. Iasi, M. Krengli, V. Landolfo, G.V. Lanza, M. Magnano, M. Mancuso, R. Maroldi, L. Masini, M.C. Merlano, M. Piemonte, S. Pisani, A. Prina-Mello, L. Prioglio, M.G. Rugiu, F. Scasso, A. Serra, G. Valente, M. Zannetti, A. Zigliani(ed.), 107th Congress of the Italian Society of Otorhinolaryngology Head and Neck Surgery (, ACTA OTORHINOLARYNGOLOGICA ITALICA, Online Conference, (40(SUPPL.1)), 27 May 2020, 2020, S1-S86 p Proceedings of a Conference, 2020 URL

Movia D, Bruni-Favier S, Prina-Mello A., In vitro Alternatives to Acute Inhalation Toxicity Studies in Animal Models-A Perspective., Frontiers in bioengineering and biotechnology, 8, 2020, p549 Journal Article, 2020 DOI TARA - Full Text

Clarke Gareth, Rogov Andrii, McCarthy Sarah, Bonacina Luigi, Gun'ko Yurii, Galez Christine, Le Dantec Ronan, Volkov Yuri, Mugnier Yannick, Prina-Mello Adriele, Author Correction: Preparation from a revisited wet chemical route of phase-pure, monocrystalline and SHG-efficient BiFeO3 nanoparticles for harmonic bio-imaging , Scientific reports , 9 , (1 ), 2019, p15891 - Journal Article, 2019 DOI URL

Clogston Jeffrey D, Hackley Vincent A, Prina-Mello Adriele, Puri Sanyogitta, Sonzini Silvia, Soo Patrick Lim, Sizing up the Next Generation of Nanomedicines, Pharmaceutical Research, 37, (1), 2019 Review, 2019 TARA - Full Text URL DOI

Prina-Mello Adriele, Regulatory Science Framework for Nanobiomaterials development - REFINE H2020 project update, NanoMed Europe 2019, Braga, 19-21 June 2019, 2019, ETP NANOMEDICINE Invited Talk, 2019

Liangfang Zhang, Jie Zheng, Chuanqi Peng, Bujie Du, Mengxiao Yu, Danielle M. Charron, Gang Zheng, Chiara Pastore, Hon S. Leong, Kimberly S. Butler, C. Jeffrey Brinker, May Azzawi, R. Steven Conlan, Christine Dufès, Andrew Owen, Steve P. Rannard, Chris Scott, Chunying Chen, Marina A. Dobrovolskaia, Serguei Kozlov, Adriele Prina"Mello, Ruth Schmid, Peter Wick, Fanny Caputo, Patrick Boisseau, Rachael M. Crist, Scott E. McNeil, Bengt Fadeel, Lang Tran, Steffen Foss Hansen, Nanna B. Hartmann, Lauge Peter Westergaard Clausen, Lars Michael Skjolding, Anders Baun, Marlene Ågerstrand, Zhen Gu, Dimitrios A. Lamprou, Clare Hoskins, Leaf Huang, Wantong Song, Huiliang Cao, Xuanyong Liu, Klaus D. Jandt, Wen Jiang, Betty Y.S. Kim, Korin E. Wheeler, Andrew J. Chetwynd, Iseult Lynch, S. Moein Moghimi, André E. Nel, Tian Xia, Paul S. Weiss, Bruno Sarmento, José das Neves, Hélder A. Santos, Luis Santos, Samir Mitragotri, Steven R. Little, Dan Peer, Mansoor M. Amiji, Mar""a José Alonso, Alke Petri"Fink, Sandor Balog, Aaron Lee, Barbara Drašler, Barbara Rothen"Rutishauser, Stefan Wilhelm, Handan Acar, Roger G. Harrison, Chuanbin Mao, Priyabrata Mukherjee, Rajagopal Ramesh, Lacey R. McNally, Sara Busatto, Joy Wolfram, Paolo Bergese, Mauro Ferrari, Ronnie H. Fang, Publisher Correction: On the issue of transparency and reproducibility in nanomedicine, Nature Nanotechnology, 14, (8), 2019, p811 - 811, p811-811 Journal Article, 2019 DOI

Hannon, G. and Lysaght, J. and Liptrott, N.J. and Prina-Mello, A., Immunotoxicity Considerations for Next Generation Cancer Nanomedicines, Advanced Science, (1900133), 2019 Journal Article, 2019 TARA - Full Text DOI

REFINE project, REFINE 1st Knowledge Exchange Conference 2019, 3 Apr 2019, In:REFINE 1st Knowledge Exchange Conference 2019, 2019, Amsterdam, Simon Bacconnier Meetings /Conferences Organised, 2019

Prina-Mello Adriele, Translational Requirements for Nanotechnology enabled medical products: SPION case study, Nanoinnovation 2019, Rome, 11-14 June 2019, 2019, Nanoinnovation organising committee Invited Talk, 2019

Crivelli B, Bari E, Perteghella S, Catenacci L, Sorrenti M, Mocchi M, Faragò S, Tripodo G, Prina-Mello A, Torre ML., Silk fibroin nanoparticles for celecoxib and curcumin delivery: ROS-scavenging and anti-inflammatory activities in an in vitro model of osteoarthritis., European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 137, 2019, p37-45 Journal Article, 2019 DOI

Fanny Caputo, Amandine Arnould, Maria Bacia, Wai Li Ling, Emilie Rustique, Isabelle Texier, Adriele Prina Mello, Anne-Claude Couffin, Measuring Particle Size Distribution by Asymmetric Flow Field Flow Fractionation: A Powerful Method for the Preclinical Characterization of Lipid-Based Nanoparticles, Molecular Pharmaceutics, 16, (2), 2019, p756-767 Journal Article, 2019 DOI

S Inder, M Bates, N Ni Labhrai, N McDermott, J Schneider, G Erdmann, T Jamerson, AN Flores, A Prina-Mello, P Thirion, PR Manecksha, D Cormican, S Finn, T Lynch, L Marignol, Multiplex profiling identifies clinically relevant signalling proteins in an isogenic prostate cancer model of radioresistance, Scientific Reports, 9, 2019, p1 - 12 Journal Article, 2019 DOI TARA - Full Text

Oliveira H, Bednarkiewicz A, Falk A, Fröhlich E, Lisjak D, Prina-Mello A, Resch S, Schimpel C, Vr"ek IV, Wysoki"ska E, Gorris HH., Critical Considerations on the Clinical Translation of Upconversion Nanoparticles (UCNPs): Recommendations from the European Upconversion Network (COST Action CM1403)., Advanced healthcare materials, 8, (1), 2019, pe1801233 Journal Article, 2019 DOI

Doroudian Mohammad, MacLoughlin Ronan, Poynton Fergus, Prina-Mello Adriele, Donnelly Seamas C, Nanotechnology based therapeutics for lung disease , Thorax , 74 , (10 ), 2019, p965 - Journal Article, 2019 DOI URL

Caputo F, Clogston J, Calzolai L, Rösslein M, Prina-Mello A., Measuring particle size distribution of nanoparticle enabled medicinal products, the joint view of EUNCL and NCI-NCL. A step by step approach combining orthogonal measurements with increasing complexity., Journal of controlled release : official journal of the Controlled Release Society, 299, 2019, p31-43 Journal Article, 2019 DOI

Prina-Mello Adriele, REFINE project establishing a regulatory science framework supporting the risk-benefit assessment of nanobiomaterial-based medical products and medical device, PTC 2019 - 12th International Particle Toxicology Conference , Salzburg, 11-13 September 2019, edited by International Particle Toxicology Conference Commitee , 2019 Poster, 2019

Sanhaji M, Göring J, Couleaud P, Aires A, Cortajarena AL, Courty J, Prina-Mello A, Stapf M, Ludwig R, Volkov Y, Latorre A, Somoza Á, Miranda R, Hilger I., The phenotype of target pancreatic cancer cells influences cell death by magnetic hyperthermia with nanoparticles carrying gemicitabine and the pseudo-peptide NucAnt., Nanomedicine, 2019 Journal Article, 2019 DOI

Prina-Mello Adriele, Translational requirements for nanotechnology enabled medical products, Magnetic nanoparticles and their applications in medicine conference, Belgrade, 4.03.2019, 2019, MAGBIOV and Vinca Institute Invited Talk, 2019

Leong, H.S. and Butler, K.S. and Brinker, C.J. and Azzawi, M. and Conlan, S. and Dufés, C. and Owen, A. and Rannard, S. and Scott, C. and Chen, C. and Dobrovolskaia, M.A. and Kozlov, S.V. and Prina-Mello, A. and Schmid, R. and Wick, P. and Caputo, F. and Boisseau, P. and Crist, R.M. and McNeil, S.E. and Fadeel, B. and Tran, L. and Hansen, S.F. and Hartmann, N.B. and Clausen, L.P.W. and Skjolding, L.M. and Baun, A. and à gerstrand, M. and Gu, Z. and Lamprou, D.A. and Hoskins, C. and Huang, L. and Song, W. and Cao, H. and Liu, X. and Jandt, K.D. and Jiang, W. and Kim, B.Y.S. and Wheeler, K.E. and Chetwynd, A.J. and Lynch, I. and Moghimi, S.M. and Nel, A. and Xia, T. and Weiss, P.S. and Sarmento, B. and das Neves, J. and Santos, H.A. and Santos, L. and Mitragotri, S. and Little, S. and Peer, D. and Amiji, M.M. and Alonso, M.J. and Petri-Fink, A. and Balog, S. and Lee, A. and Drasler, B. and Rothen-Rutishauser, B. and Wilhelm, S. and Acar, H. and Harrison, R.G. and Mao, C. and Mukherjee, P. and Ramesh, R. and McNally, L.R. and Busatto, S. and Wolfram, J. and Bergese, P. and Ferrari, M. and Fang, R.H. and Zhang, L. and Zheng, J. and Peng, C. and Du, B. and Yu, M. and Charron, D.M. and Zheng, G. and Pastore, C., On the issue of transparency and reproducibility in nanomedicine, Nature Nanotechnology, 14, (7), 2019, p629-635 Journal Article, 2019 DOI

Movia Dania, Bazou Despina, Prina-Mello Adriele, ALI multilayered co-cultures mimic biochemical mechanisms of the cancer cell-fibroblast cross-talk involved in NSCLC MultiDrug Resistance, BMC Cancer, 19, (1), 2019, p854- Journal Article, 2019 URL DOI

Prina-Mello Adriele, Challenges in translating a nano-thermal therapy to the clinic, Annual conference of the Italian Society of Photobiology, Bologna, 19-21 June 2019, 2019, italian society of photobiology Invited Talk, 2019

Prina-Mello Adriele, Assay validation: irinotecan-based nanomedcine study, Controlled Release Society Annual event, Valencia, 21-24 July 2019, 2019, Controlled Release Society Invited Talk, 2019

Moustaoui H, Saber J, Djeddi I, Liu Q, Movia D, Prina-Mello A, Spadavecchia J, Lamy de la Chapelle M, Djaker N., A protein corona study by scattering correlation spectroscopy: a comparative study between spherical and urchin-shaped gold nanoparticles., Nanoscale, 11, (8), 2019, p3665-3673 Journal Article, 2019 DOI

Precision Nanomedicine, Andover Massachusetts United States, Andover House, Inc., [eds.], 2018 Editorial Board, 2018 URL

Luisana Di Cristo, Sarah Mc Carthy, Keith Paton, Dania Movia, Adriele Prina-Mello, Interplay between oxidative stress and endoplasmic reticulum stress mediated- autophagy in unfunctionalised few-layer graphene-exposed macrophages, 2D Materials, 2018 Journal Article, 2018 DOI

Adriele Prina-Mello, A Systematic Approach to Endotoxin Contamination Assessment of Iron Oxide Nanoparticles, Scientific and Clinical Application of Magnetic Nanocarriers, Copenhagen, Denmark, 24-27 May 2018, 2018 Oral Presentation, 2018

Adriele Prina-Mello and Dania Movia and Despina Bazou and Yuri Volkov and Adriele Prina-Mello, Multilayered Cultures of NSCLC cells grown at the Air-Liquid Interface allow the efficacy testing of inhaled anti-cancer drugs, Scientific Reports, 2018, p12920- Journal Article, 2018 TARA - Full Text DOI

Hutchinson D, Muller J, McCarthy JE, Gun'ko YK, Verma NK, Bi X, Di Cristo L, Kickham L, Movia D, Prina-Mello A, Volkov Y, Cadmium nanoparticles citrullinate cytokeratins within lung epithelial cells: cadmium as a potential cause of citrullination in chronic obstructive pulmonary disease, International Journal of Chronic Obstructive Pulmonary Disease , 13, 2018, p441 - 449 Journal Article, 2018 URL DOI TARA - Full Text URL

Ciarán Manus Maguire, Michelle Lavin, Mairead M. Doyle, Mary Byrne, Adriele Prina-Mello, James S. O'Donnell, Yuri Volkov, The anticoagulant properties of cadmium telluride quantum dots, Journal of Interdisciplinary Nanomedicine, 3, (1), 2018, p16 - 28, p16-28 Journal Article, 2018 DOI

Prina-Mello, Adriele and Maguire, Ciaran Magus and Savage, John, Origins to Outcomes: A Role for Extracellular Vesicles in Precision Medicine, Precision Nanomedicine, 2018, p18--42 Journal Article, 2018

Multiparametric Preclinical Assessment of Theranostics Materials (Chapter 17) in, editor(s)Conde, Joao , Handbook of Nanomaterials for Cancer Theranostics, Elsevier, 2018, pp517 - 535, [Prina-Mello Adriele] Book Chapter, 2018 DOI URL

Adriele Prina-Mello , Characterisation of particles in solution \textendash a perspective on light scattering and comparative technologies, Science and Technology of Advanced Materials, 2018 Journal Article, 2018 DOI

Cristina Multari, Marta Miola, Sara Ferraris, Dania Movia, Kristina Žužek Rožman, Nina Kostevšek, Antonia Follenzi, Enrica Verné, Adriele Prina-Mello, Synthesis and characterization of silica-coated superparamagnetic iron oxide nanoparticles and interaction with pancreatic cancer cells, International Journal of Applied Ceramic Technology, 2018 Journal Article, 2018 DOI

Adriele Prina-Mello, Namrata Jain, Baiyun Liu, Jason I. Kilpatrick, Melissa A. Tutty, Alan P. Bell, Suzanne P Jarvis, Yuri Volkova, Dania Movia, Culturing substrates influence the morphological, mechanical and biochemical features of lung adenocarcinoma cells cultured in 2D or 3D, Tissue and Cell, 50, 2018, p15 - 30 Journal Article, 2018 DOI

Scientific Reports, https://www.nature.com/srep/, Springer Nature Publishing AG, [eds.], 2018 Editorial Board, 2018

Adriele Prina-Mello, FUTURE MEDICINE nanotechnology applied to medicine: an advanced tools to the benefit of patients. Trends, emerging technologies and impact to society, Open Campus: Future of Nanomedicine, Gratz, (Austria), 28 Feb 2018, 2018 Oral Presentation, 2018

Academia di Gagliato organising committee, NanoGagliato 2018, 22-23 Jul 2018, 2018, Gagliato (Italy) Meetings /Conferences Organised, 2018

Nanotoxicity in cancer research: technical protocols and tips considerations for the use of 3D tumour spheroids in, editor(s)Ferreira de Castro Gomes Andreia, Sárria Pereira Passos Marisa. , Unraveling the Safety Profile of Nanoscale Particles and Materials - From Biomedical to Environmental Applications, InTech, 2018, [Movia D., Prina-Mello A.] Book Chapter, 2018 TARA - Full Text DOI

Adriele Prina-Mello, EU Nanomedicine Characterisation Laboratory: Physicochemical characterisation, CLINAM European Foundation for Clinical Nanomedicine SUMMIT, Basel Switzerland, 4 Sep 2018, 2018 Invited Talk, 2018 URL

Gioria S, Caputo F, Urbán P, Maguire CM, Bremer-Hoffmann S, Prina-Mello A, Calzolai L, Mehn D., Are existing standard methods suitable for the evaluation of nanomedicines: some case studies., Nanomedicine (London, England), 2018 Journal Article, 2018 DOI TARA - Full Text

Mohamed BM, Boyle NT, Schinwald A, Murer B, Ward R, Mahfoud OK, Rakovich T, Crosbie-Staunton K, Gray SG, Donaldson K, Volkov Y, Prina-Mello A., Induction of protein citrullination and auto-antibodies production in murine exposed to nickel nanomaterials., Scientific Reports, 8, (679), 2018 Journal Article, 2018 URL DOI TARA - Full Text

CLINAM European Foundation Workshop committee, CLINAM European Foundation for Clinical Nanomedicine SUMMIT - Workshop, 2-5 Sep 2018, 2018, Basel Conference centre, Basel, Switzerland, Worked with CLINAM team to programme and workshop organisation Meetings /Conferences Organised, 2018 URL

Clarke, G. and Rogov, A. and McCarthy, S. and Bonacina, L. and Gun'Ko, Y. and Galez, C. and Le Dantec, R. and Volkov, Y. and Mugnier, Y. and Prina-Mello, A., Preparation from a revisited wet chemical route of phase-pure, monocrystalline and SHG-efficient BiFeO3nanoparticles for harmonic bio-imaging, Scientific Reports, 8, (1), 2018 Journal Article, 2018 TARA - Full Text DOI

Di Cristo, L. and Maguire, C.M. and Mc Quillan, K. and Aleardi, M. and Volkov, Y. and Movia, D. and Prina-Mello, A., Towards the identification of an in vitro tool for assessing the biological behavior of aerosol supplied nanomaterials, International Journal of Environmental Research and Public Health, 15, (4), 2018 Journal Article, 2018 DOI TARA - Full Text

Marassi, Valentina and Di Cristo, Luisana and Smith, Stephen G J and Ortelli, Simona and Blosi, Magda and Costa, Anna L and Reschiglian, Pierluigi and Volkov, Yuri and Prina-Mello, Adriele, Silver nanoparticles as a medical device in healthcare settings: a five-step approach for candidate screening of coating agents, Royal Society open science, 5, (1), 2018, p171113 Journal Article, 2018 TARA - Full Text DOI

Immunotoxicity and Safety Considerations for Iron Oxide Nanoparticles in, editor(s)Nguyen TK Thanh , Clinical Applications of Magnetic Nanoparticles: From Fabrication to Clinical Applications, Online, CRC press, 2018, pp273 - [Gary Hannon, Melissa Anne Tutty, Adriele Prina-Mello] Book Chapter, 2018

Adriele Prina-Mello, Next Generation Nanomedicine: lesson learned from the EU Nanomedicine Characterization Laboratory, Advanced School in Nanomedicine, 17th edition of the Summer School for Italian PhD students in Pharmaceutical Technology , Pula (Italy), 27-29 Sep 2017, 2017 Oral Presentation, 2017

Adriele Prina-Mello, The conceptual problems of nanomaterials application in translational medicine, 1st International School-conference for young researchers on Smart nanosystems for translation medicine, San Petersburg, Russia, 30 Nov 2017, 2017 Oral Presentation, 2017

Ignacio Martin-Loeches, Robert Forster, Adriele Prina-Mello, Intensive care medicine in 2050: nanotechnology. Emerging technologies and approaches and their impact on critical care, Intensive Care Medicine, 2017 Journal Article, 2017

Martin-Loeches Ignacio, Muriel-Bombin Arturo, Ferrer Ricard, Artigas Antonio, Sole-Violan Jordi, Lorente Leonardo, Andaluz-Ojeda David, Prina-Mello Adriele, Herran-Monge Ruben, Suberviola Borja, The protective association of endogenous immunoglobulins against sepsis mortality is restricted to patients with moderate organ failure , Annals of Intensive Care , 7 , (1 ), 2017, p44 - Journal Article, 2017 TARA - Full Text

Adriele Prina-Mello, First Generation Nanomedicine: lesson learned from the Characterization perspective, British Society for Nanomedicine Annual Young Researcher Event, Belfast, 11 Aug 2017, 2017 Oral Presentation, 2017

Adriele Prina-Mello, Cancer Theranostics: a Translational Nanomedicine Perspective, BIONANOMED, Krems (Austria), 15 May 2017, 2017 Oral Presentation, 2017

Baird A, Easty D, Mohamed BM, Jarzabek M, Shiels L, Soltermann A, Raeppel S, McDonagh L, Clarke G, Crosbie-Staunton K, 56: Multiple RTK targeting as a therapeutic option in malignant pleural mesothelioma , Lung Cancer , 103 , 2017, pS26 - Journal Article, 2017

Gerlach JQ, Maguire CM, KrÃŒger A, Joshi L, Prina-Mello A, Griffin MD., Urinary nanovesicles captured by lectins or antibodies demonstrate variations in size and surface glycosylation profile., Nanomedicine (London, England), 12, (11), 2017, p1217-1229 Journal Article, 2017 DOI

Collins AR, Annangi B, Rubio L, Marcos R, Dorn M, Merker C, Estrela-Lopis I, Cimpan MR, Ibrahim M, Cimpan E, Ostermann M, Sauter A, Yamani NE, Shaposhnikov S, Chevillard S, Paget V, Grall R, Delic J, de-Cerio FG, Suarez-Merino B, Fessard V, Hogeveen KN, Fjellsbø LM, Pran ER, Brzicova T, Topinka J, Silva MJ, Leite PE, Ribeiro AR, Granjeiro JM, Grafström R, Prina-Mello A, Dusinska M., High throughput toxicity screening and intracellular detection of nanomaterials., Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 9, (1), 2017 Journal Article, 2017 DOI

Ajetunmobi A, McAllister D, Jain N, Brazil O, Corvin A, Volkov Y, Tropea D, Prina-Mello A, Characterisation of SH-SY5Y Human Neuroblastoma cell growth over glass and SU-8 substrates., Journal of Biomedical Materials Research - Part A, 105, (8), 2017, p2129-2138 Journal Article, 2017 DOI

Adriele Prina-Mello, EC Regulatory policies on the use of Nanomaterials in Nanomedicine and Risk Assessment, Kazan Medical School Symposium, Kazan, Russia, 15 Mar 2018, 2017 Oral Presentation, 2017

D Hutchinson, J Müller, JE McCarthy, Y Gun'ko, N Verma, X Bi, L Di Cristo, L Kickham, D Movia, A Prina-Mello, Y Volkov, AB0111"Cadmium nanoparticles citrullinate intracellular cytokeratins: cadmium potentially links rheumatoid arthritis to smoking and numerous working class occupations, Abstracts Accepted for Publication, 2017 Conference Paper, 2017 DOI

Martin-Loeches Ignacio, Muriel-Bombin Arturo, Ferrer Ricard, Artigas Antonio, Sole-Violan Jordi, Lorente Leonardo, Andaluz-Ojeda David, Prina-Mello Adriele, Herran-Monge Ruben, Suberviola Borja, The Protective Association Of Endogenous Immunoglobulins Against Sepsis Mortality Is Restricted To Patients With Moderate Organ Failure. , 2017 Working Paper, 2017

Ciarán M. Maguire, Katherine Sillence, Matthias Roesslein, Claire Hannell, Guillaume Suarez, Jean-Jacques Sauvain, Sonja Capracotta, Servane Contal, Sebastien Cambier, Naouale El Yamani, Maria Dusinska, Agnieszka Dybowska, Antje Vennemann, Laura Cooke, Andrea Haase, Andreas Luch, Martin Wiemann, Arno Gutleb, Rafi Korenstein, Michael Riediker, Peter Wick, Patrick Hole and Adriele Prina-Mello, Benchmark of Nanoparticle Tracking Analysis on Measuring Nanoparticle Sizing and Concentration, Journal of Micro and Nano-Manufacturing, 5, (4), 2017, p041002-1 - 041002-10 Journal Article, 2017 DOI TARA - Full Text URL

Kuznetsova VA, Visheratina AK, Ryan A, Martynenko IV, Loudon A, Maguire CM, Purcell-Milton F, Orlova AO, Baranov AV, Fedorov AV, Prina-Mello A, Volkov Y, Gun'Ko YK., Enantioselective cytotoxicity of ZnS:Mn quantum dots in A549 cells., Chirality, 2017, p403-408 Journal Article, 2017 DOI

Volkov, Y., McIntyre, J., Prina-Mello, A., Graphene toxicity as a double-edged sword of risks and exploitable opportunities: A critical analysis of the most recent trends and developments, 2D Materials, 4, (2), 2017 Journal Article, 2017 DOI

Movia D., Di Cristo L., Alnemari R., McCarthy J. E., Moustaoui H., Lamy de la Chapelle M., Spadavecchia J., Volkov Y., Prina-Mello A., The curious case of how mimicking physiological complexity in in vitro models of the human respiratory system influences the inflammatory responses. A preliminary study focused on gold nanoparticles, Journal of Interdisciplinary Nanomedicine, 2, (2), 2017, p110 - 130 Journal Article, 2017 DOI

Bergamaschi, E., Guseva Canu, I., Prina-Mello, A., Magrini, A., Biomonitoring, Adverse Effects of Engineered Nanomaterials: Exposure, Toxicology, and Impact on Human Health: Second Edition, 2017, p125-158 Book, 2017 DOI

Ignacio Martin-Loeches, Arturo Muriel-Bombin, Ricard Ferrer, Antonio Artigas, Jordi Sole-Violan, Leonardo Lorente, David Andaluz-Ojeda, Adriele Prina-Mello, Ruben Herran-Monge, Borja Suberviola, Ana Rodriguez-Fernandez, Pedro Merino, Ana M Loza, Pablo Garcia-Olivares, Eduardo Anton, Eduardo Tamayo, Wysali Trapiello, Jesus Blanco, Jesus F Bermejo-Martin, GRECIA Group, The Protective Association Of Endogenous Immunoglobulins Against Sepsis Mortality Is Restricted To Patients With Moderate Organ Failure., 2017 Miscellaneous, 2017 DOI

Bregoli, L., Movia, D., Gavigan-Imedio, J.D., Lysaght, J., Reynolds, J., Prina-Mello, A., Nanomedicine applied to translational oncology: A future perspective on cancer treatment, Nanomedicine: Nanotechnology, Biology, and Medicine, 12, (1), 2016, p81-103 Journal Article, 2016 DOI

Dekkers S, Oomen AG, Bleeker EA, Vandebriel RJ, Micheletti C, Cabellos J, Janer G, Fuentes N, Vázquez-Campos S, Borges T, Silva MJ, Prina-Mello A, Movia D, Nesslany F, Ribeiro AR, Leite PE, Groenewold M, Cassee FR, Sips AJ, Dijkzeul A, van Teunenbroek T, Wijnhoven SW, Towards a nanospecific approach for risk assessment., Regulatory toxicology and pharmacology : RTP, 80, 2016, p46-59 Journal Article, 2016 TARA - Full Text DOI

Biomonitoring in, editor(s)Fadel B., Pietroiusti A., Shvedova A.A. , Adverse Effects of Engineered Nanomaterials, Academic Press, Elsevier Academic Press, 2016, pp125 - 160, [Bergamaschi E., Guseva Canu I, Prina-Mello A., Magrini A.] Book Chapter, 2016

Multilayered nanoparticles for personalized medicine: Translation into clinical markets in, 2016, pp299-318 , [Movia, D., Poland, C., Tran, L., Volkov, Y., Prina-Mello, A.] Book Chapter, 2016

Di Cristo L, Movia D, Bianchi MG, Allegri M, Mohamed BM, Bell AP, Moore C, Pinelli S, Rasmussen K, Riego-Sintes J, Prina-Mello A, Bussolati O, Bergamaschi E, Proinflammatory Effects of Pyrogenic and Precipitated Amorphous Silica Nanoparticles in Innate Immunity Cells., Toxicological sciences, 150, (1), 2016, p40-53 Journal Article, 2016 DOI TARA - Full Text

Cancer Nanotechnology, https://cancer-nano.biomedcentral.com/, BMC Springer Nature, [eds.], 2016 Editorial Board, 2016

Hassan R, Alley E, Kindler H, Antonia S, Jahan T, Grous J, Honarmand S, Mcdougall K, Whiting C, Nair N, 86 When RON MET TAM: potential interventions for mesothelioma therapy , 2016 Journal Article, 2016

Moustaoui H, Movia D, Dupont N, Bouchemal N, Casale S, Djaker N, Savarin P, Prina-Mello A, De La Chapelle M.L, Spadavecchia J, Tunable Design of Gold(III)-Doxorubicin Complex-PEGylated Nanocarrier. the Golden Doxorubicin for Oncological Applications, ACS Applied Materials and Interfaces, 8, (31), 2016, p19946 - 19957 Journal Article, 2016 DOI URL

Volkov Yuri, McIntyre Jennifer, Prina-Mello Adriele, Graphene toxicity as a double-edged sword of risks and exploitable opportunities: A critical analysis of the most recent trends and developments , 2D Materials , 2016 Review, 2016 DOI

Multilayered Nanoparticles for Personalized Medicine: Translation into Clinical Markets in, editor(s)Bawa R., Audette G.F. and Rubinstein I. , Handbook of Clinical Nanomedicine - From Bench to Bedside, Singapore, Pan Stanford Publishing, 2016, [Movia D., Poland C., Tran L., Volkov Y., Prina-Mello A. ] Book Chapter, 2016

Edge D, Shortt CM, Gobbo OL, Teughels S, Prina-Mello A, Volkov Y, MacEneaney P, Radomski MW, Markos F, Pharmacokinetics and bio-distribution of novel super paramagnetic iron oxide nanoparticles (SPIONs) in the anaesthetized pig., Clinical and experimental pharmacology & physiology, 43, (3), 2016, p319-326 Journal Article, 2016 DOI

Spadavecchia J, Movia D, Moore C, Maguire CM, Moustaoui H, Casale S, Volkov Y, Prina-Mello A, Targeted polyethylene glycol gold nanoparticles for the treatment of pancreatic cancer: from synthesis to proof-of-concept in vitro studies., International journal of nanomedicine, 11, 2016, p791-822 Journal Article, 2016 TARA - Full Text DOI

Doroudian M, O'Reilly C, Crosbie-Staunton K, MacLoughlin R, Prina-Mello A, Volkov Y, Donnelly SC, Good Things Come in Small Packages: An Aerosolized Delivery System for Small Molecule Inhibitors of Macrophage Migration Inhibitory Factor , 2016, 185 , SPRINGER LONDON LTD 236 GRAYS INN RD, 6TH FLOOR, LONDON WC1X 8HL, ENGLAND , 2016, ppS467 - S468 Conference Paper, 2016

Staedler D, Passemard S, Magouroux T, Rogov A, Maguire CM, Mohamed BM, Schwung S, Rytz D, Jüstel T, Hwu S, Mugnier Y, Le Dantec R, Volkov Y, Gerber-Lemaire S, Prina-Mello A, Bonacina L, Wolf JP, Cellular uptake and biocompatibility of bismuth ferrite harmonic advanced nanoparticles., Nanomedicine : nanotechnology, biology, and medicine, 11, (4), 2015, p815-24 Journal Article, 2015

Joint ETPN and local Irish organising committee, European Technology Platform in NANOMEDICINE, 10th Annual event, 12-14 Oct 2015, 2015, IMM, TCD Meetings /Conferences Organised, 2015 URL

Prina-Mello A., Bonacina L., Frontiers , Nature Publishing Group, Frontiers online, Nature Publishing Group, 2015 Book, 2015

Bianca M Rotoli, Rita Gatti, Dania Movia, Massimiliano G Bianchi, Luisana Di Cristo, Ivana Fenoglio, Fabio Sonvico, Enrico Bergamaschi, Adriele Prina-Mello, Ovidio Bussolati, Identifying contact-mediated, localized toxic effects of MWCNT aggregates on epithelial monolayers: a single-cell monitoring toxicity assay, Nanotoxicology, 9, (2), 2015, p230-241 Journal Article, 2015 DOI

Calero M., Chiappi M., Lazaro-Carrillo A., Rodríguez M., Chichón F., Crosbie-Staunton K., Prina-Mello A., Volkov Y., Villanueva A., Carrascosa J., Characterization of interaction of magnetic nanoparticles with breast cancer cells, Journal of Nanobiotechnology, 13, (1), 2015 Journal Article, 2015 DOI

Samuel S., Santos-Martinez M., Medina C., Jain N., Radomski MW., Prina-Mello A., Volkov Y., CdTe quantum dots induce activation of human platelets: Implications for nanoparticle hemocompatibility, International Journal of Nanomedicine, 10, 2015, p2723-2734 Journal Article, 2015 TARA - Full Text DOI

Bergamaschi E., Poland C., Poland C., Guseva Canu I., Guseva Canu I., Prina-Mello A., Prina-Mello A., The role of biological monitoring in nano-safety, Nano Today, 10, (3), 2015, p274 - 277 Journal Article, 2015 DOI

Gobbo OL, Sjaastad K, Radomski MW, Volkov Y, Prina-Mello A, Magnetic Nanoparticles in Cancer Theranostics., Theranostics, 5, (11), 2015, p1249-63 Review, 2015 TARA - Full Text DOI URL

Staedler D, Passemard S, Magouroux T, Rogov A, Maguire CM, Mohamed BM, Schwung S, Rytz D, Justel T, Hwu S, Mugnier Y, Le Dantec R, Volkov Y, Gerber-Lemaire S, Prina-Mello A, Bonacina L, Wolf JP, Cellular uptake and biocompatibility of bismuth ferrite harmonic advanced nanoparticles, Nanomedicine, 11, (4), 2015, p815 - 824 Journal Article, 2015 URL DOI

Kossatz S., Grandke J., Couleaud P., Latorre A., Aires A., Crosbie-Staunton K., Ludwig R., DÃ"hring H., Ettelt V., Lazaro-Carrillo A., Calero M., Sader M., Courty J., Volkov Y., Prina-Mello A., Villanueva A., Somoza à ., Cortajarena A., Miranda R., Hilger I., Efficient treatment of breast cancer xenografts with multifunctionalized iron oxide nanoparticles combining magnetic hyperthermia and anti-cancer drug delivery, Breast Cancer Research, 17, (1), 2015 Journal Article, 2015 DOI

Bianchi M., Allegri M., Costa A., Blosi M., Gardini D., Del Pivo C., Prina-Mello A., Di Cristo L., Bussolati O., Bergamaschi E., Titanium dioxide nanoparticles enhance macrophage activation by LPS through a TLR4-dependent intracellular pathway, Toxicology Research, 4, (2), 2015, p385-398 Journal Article, 2015 DOI

Gobbo O., Wetterling F., Vaes P., Teughels S., Markos F., Edge D., Shortt C., Crosbie-Staunton K., Radomski M., Volkov Y., Prina-Mello A., Biodistribution and pharmacokinetic studies of SPION using particle electron paramagnetic resonance, MRI and ICP-MS, Nanomedicine, 10, (11), 2015, p1751-1760 Journal Article, 2015 DOI

Laura Christine Kickham, Anthony M McElligott, Adriele Prina-Mello, Elisabeth A Vandenberghe, Yuri Volkov, Paul Browne, Interrogating the Interaction of CD52 Functionalised Metallic Nanoparticles with Malignant B Lymphocytes, 126, (23), 2015 Published Abstract, 2015 DOI DOI URL DOI DOI

Catherine A Schütz, Davide Staedler, Kieran Crosbie-Staunton, Dania Movia, Catherine Chapuis Bernasconi, Blanka Halamoda Kenzaoui, Adriele Prina-Mello, Lucienne Juillerat-Jeannere, Differential stress reaction of human colon cells to oleic-acid-stabilized and unstabilized ultrasmall iron oxide nanoparticles, International Journal of Nanomedicine, 9, 2014, p3481 - 3498 Journal Article, 2014 DOI TARA - Full Text

High Content Screening and Analysis with Nanotechnologies in, Alves F., Kiessling F. , Comprehensive Biomedical Physics - special isuse, Online , Science Direct, 2014, pp379 - 389, [Williams Y, Prina-Mello A, Volkov Y] Book Chapter, 2014 DOI

Rakovich TY, Mahfoud OK, Mohamed BM, Prina-Mello A, Crosbie-Staunton K, Van Den Broeck T, De Kimpe L, Sukhanova A, Baty D, Rakovich A, Maier SA, Alves F, Nauwelaers F, Nabiev I, Chames P, Volkov Y, Highly sensitive single domain antibody-quantum dot conjugates for detection of HER2 biomarker in lung and breast cancer cells., ACS nano, 8, (6), 2014, p5682-95 Journal Article, 2014

Maguire C., Mahfoud O., Rakovich T., Gerard V., Prina-Mello A., Prina-Mello A., Gun'ko Y., Gun'ko Y., Volkov Y., Volkov Y., Heparin conjugated quantum dots for in vitro imaging applications, Nanomedicine: Nanotechnology, Biology, and Medicine, 10, (8), 2014, p1853-1861 Journal Article, 2014 DOI

Mahfoud, O.K., Rakovich, T.Y., Prina-Mello, A., Movia, D., Alves, F., Volkov, Y., Detection of ErbB2: Nanotechnological solutions for clinical diagnostics, RSC Advances, 4, (7), 2014, p3422-3442 Review Article, 2014 DOI TARA - Full Text

Sebastian Schwung, Andrii Rogov, Gareth Clarke, Cécile Joulaud, Thibaud Magouroux, Davide Staedler, Solène Passemard, Thomas Jüstel, Laurent Badie, Christine Galez, Jean Pierre Wolf, Yuri Volkov, Adriele Prina-Mello, Sandrine Gerber-Lemaire, Daniel Rytz, Yannick Mugnier, Luigi Bonacina, Ronan Le Dantec, Nonlinear optical and magnetic properties of BiFeO3 harmonic nanoparticles, Journal of Applied Physics, 116, (11), 2014, p114306- Journal Article, 2014

Shortt C., Edge D., Teughels S., Roskin E., Verbiest J., Gobbo O., Prina-Mello A., Volkov Y., Markos F., Bio-distribution of superparagmetic iron oxide nanoparticles (SPION's) in the pig (LB578), The FASEB Journal, 28, (1), 2014, pLB578- Journal Article, 2014

Shortt, Christine, Edge, Deirdre, Teughels, Stephanie, Roskin, Eric, Verbiest, Joeri, Gobbo, Oliviero, Prina"Mello, Adriele, Volkov, Yuri, Markos, Farouk, Bio"distribution of superparagmetic iron oxide nanoparticles (SPION"s) in the pig (LB578), The FASEB Journal, 28, (S1), 2014 Journal Article, 2014 DOI

Maguire CM, Mahfoud OK, Rakovich T, Gerard VA, Prina-Mello A, Gun'ko Y, Volkov Y, Heparin conjugated quantum dots for in vitro imaging applications., Nanomedicine : nanotechnology, biology, and medicine, 10, (8), 2014, p1853-61 Journal Article, 2014

Ronzoni F, Magouroux T, Vernet R, Extermann J, Crotty D, Prina-Mello A, Ciepielewski D, Volkov Y, Bonacina L, Wolf JP, Jaconi M, Harmonic nanoparticles for regernerative research, Journal of Visualized Experiments, (87), 2014 Journal Article, 2014 URL DOI

Ronzoni F, Magouroux T, Vernet R, Extermann J, Crotty D, Prina-Mello A, Ciepielewski D, Volkov Y, Bonacina L, Wolf JP, Jaconi M, Harmonic nanoparticles for regenerative research., Journal of visualized experiments : JoVE, (87), 2014 Journal Article, 2014 DOI

Rakovich TY, Mahfoud OK, Mohamed BM, Prina-Mello A, Crosbie-Staunton K, Van Den Broeck T, De Kimpe L, Sukhanova A, Baty D, Rakovich A, Maier SA, Alves F, Nauwelaers F, Nabiev I, Chames P, Volkov Y, Highly sensitive single domain antibody-quantum dot conjugates for detection of HER2 biomarker in ling and breast cancer cells., tcd, 2014 Dataset, 2014 URL

Movia, D., Gerard, V., Maguire, C.M., Jain, N., Bell, A.P., Nicolosi, V., O'Neill, T., Scholz, D., Gun'ko, Y., Volkov, Y., Prina-Mello, A., A safe-by-design approach to the development of gold nanoboxes as carriers for internalization into cancer cells, Biomaterials, 35, (9), 2014, p2543-2557 Journal Article, 2014 DOI

Clark Gareth, Mugnier Yannick, Le Dantec Ronan, Gunko Yurii, Rytz Daniel, Galez Christine, Volkov Yu M, Prina-Mello Adriele, Phase pure, monocrystalline bismuth ferrite nanoparticles for biomedical applications , 2014, 2014 Conference Paper, 2014

Williams, Y., Prina-Mello, A., Volkov, Y., High Content Screening and Analysis with Nanotechnologies, Comprehensive Biomedical Physics, 4, 2014, p379-389 Book, 2014 DOI

Schütz CA, Staedler D, Crosbie-Staunton K, Movia D, Chapuis Bernasconi C, Kenzaoui BH, Prina-Mello A, Juillerat-Jeanneret L, Differential stress reaction of human colon cells to oleic-acid-stabilized and unstabilized ultrasmall iron oxide nanoparticles., International journal of nanomedicine, 9, 2014, p3481-98 Journal Article, 2014 DOI TARA - Full Text

Ajetunmobi,A. A., Prina-Mello,Adriele A., Volkov,Yuri Y., Corvin,Aiden P. A.P., Tropea,Daniela D., Nanotechnologies for the study of the central nervous system, Progress in Neurobiology, 123, 2014, p18-36 Journal Article, 2014 DOI TARA - Full Text

Ciaran Manus Maguire, Omar Kazem Mahfoud, Tatsiana Rakovich, Valerie Anne Gerard, Adriele Prina-Mello, Yurii Gun'ko, Yuri Volkov, Prina-Mello Adriele Prina-Mello Adriele Heparin conjugated quantum dots for in vitro imaging applications, Nanomedicine: Nanotechnology, Biology and Medicine, 10, (8), 2014, p1853 - 1861 Review Article, 2014

CLINAM European Foundation organising committee, CLINAM European Foundation for Clinical Nanomedicine SUMMIT - Workshop, 23-25 Jun 2014, 2014, Basel Conference centre, Basel, Switzerland Meetings /Conferences Organised, 2014 URL

Gobbo OL, Fagan J, Ryan C, Edge D, Shortt C, Markos F, Radomski MW, Prina-Mello A and Y Volkov, Quantification of Iron Oxide Nanoparticles in a large animal model using MRI, ISMRM, 2014 Poster, 2014

Harmonic Nanoparticles for Regenerative Research Authors, Flavio Ronzoni, Thibaud Magouroux, Remi Vernet, Jérôme Extermann, Darragh Crotty, Adriele Prina-Mello, Daniel Ciepielewski, Yuri Volkov, Luigi Bonacina, Jean-Pierre Wolf, Marisa Jaconi Publication date, JoVE (Journal of Visualized Experiments), (87), 2014, pe51333- Review Article, 2014

Hole P, Sillence K, Hannell C, Maguire CM, Roesslein M, Suarez G, Capracotta S, Magdolenova Z, Horev-Azaria L, Dybowska A, Cooke L, Haase A, Contal S, Manø S, Vennemann A, Sauvain JJ, Staunton KC, Anguissola S, Luch A, Dusinska M, Korenstein R, Gutleb AC, Wiemann M, Prina-Mello A, Riediker M, Wick P, Interlaboratory comparison of size measurements on nanoparticles using nanoparticle tracking analysis (NTA)., Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology, 15, 2013, p2101 Journal Article, 2013

Bashir Mustafa Mohamed, Dania Movia, Anton Knyazev, Dominique Langevin, Anthony Mitchell Davies, Adriele Prina-Mello, Yuri Volkov, Citrullination as early-stage indicator of cell response to Single-Walled Carbon Nanotubes, Scientific Reports, 3, (1124), 2013, p1 - 7 Journal Article, 2013 DOI

Gao Y, Mohamed BM, Prina-Mello A, O'Byrne KJ, Gray SG, 85 KAT5 and KDM6B may be candidate therapeutic targets in malignant pleural mesothelioma , Lung Cancer , 79 , 2013, pS30 - Journal Article, 2013

Gobbo OL, Wetterling F, Crosbie-Staunton K, Vaes P, Teughels S, Markos F, Radomski MW, Prina-Mello A and Volkov Y, Pharmacokinetics and biodistribution of superparamagnetic nanoparticles using pEPR in the mouse: an in vivo, in vitro and ex vivo validation, ISMRM, 2013 Poster, 2013

Advanced Methodologies and Techniques for Assessing Nanomaterials Toxicity: from manufacturing to nanomedicine screening in, editor(s)Nancy A. Monteiro-Riviere & C. Lang Tran , Nanotoxicology, Second Edition, Taylor & Francis, Informa Healthcare Books, CRC Press, 2013, pp155 - [Prina-Mello Adriele, Mohamed Bashir M, Verma Navin K, Jain Namrata, Volkov Yuri] Book Chapter, 2013

Prina-Mello A, Crosbie-Staunton K, Salas G, Del Puerto Morales M, Volkov Y. , Multiparametric toxicity evaluation of SPIONs by high content screening technique: Identification of biocompatible multifunctional nanoparticles for nanomedicine , IEEE Transactions on Magnetics, 49, (1), 2013, p377 - 382 Journal Article, 2013 DOI

Samuel, S.P., Jain, N., O'Dowd, F., Paul, T., Kashanin, D., Gerard, V.A., Gun'ko, Y.K., Prina-Mello, A., Volkov, Y. , Nanoparticles uptake by human endothelial cells under shear flow, Proceedings of the 19th Bioengineering Ireland., 19th Bioengineering Ireland, Co. Meath, Dublin, 18-19 January 2013, edited by Kelly, Murphy, Buckley , The Trinity Centre for Bioengineering, 2013 Conference Paper, 2013

Mohamed BM, Movia D, Knyazev A, Langevin D, Davies AM, Prina-Mello A, Volkov Y, Citrullination as early-stage indicator of cell response to single-walled carbon nanotubes., Scientific reports, 3, 2013, p1124 Journal Article, 2013 DOI TARA - Full Text

Singh, M., Movia, D., Mahfoud, O.K., Volkov, Y., Prina-Mello, A., Silver nanowires as prospective carriers for drug delivery in cancer treatment: An in vitro biocompatibility study on lung adenocarcinoma cells and fibroblasts, European Journal of Nanomedicine, 5, (4), 2013, p195-204 Journal Article, 2013 DOI

Darragh Crotty, Gary Silkstone, Soumya Poddar, Richard Ranson, Adriele Prina-Mello, Michael T. Wilson, and J. M. D. Coey, Reexamination of magnetic isotope and field effects on adenosine triphosphate production by creatine kinase, Proceedings of the National Academy of Sciences of the United States of America, 109, (18), 2012, p7126 Journal Article, 2012 TARA - Full Text

Mohamed BM, Verma NK, Davies AM, McGowan A, Crosbie-Staunton K, Prina-Mello A, Kelleher D, Botting CH, Causey CP, Thompson PR, Pruijn GJ, Kisin ER, Tkach AV, Shvedova AA, Volkov Y, Citrullination of proteins: a common post-translational modification pathway induced by different nanoparticles in vitro and in vivo., Nanomedicine (London, England), 7, (8), 2012, p1181-1195 Journal Article, 2012 DOI

Suzuki J., Balasubramaniam S. and Prina-Mello A, Multiobjective TDMA Optimization for Neuron-based Molecular Communication, BODYNETS 2012 , 7th International Conference on Body Area Networks. BODYNETS 2012 , Norway, 24-26 September 2012, edited by BODYNETS conference organisers , 2012, BODYNETS, 2012 Conference Paper, 2012 DOI

Pini G., Scusa M.F., Congiu L., Benincasa A., Morescalchi P., Bottiglioni I., Di Marco P., Borelli P., Bonuccelli U., Della Chiesa A., Prina-Mello A., Tropea D., , IGF1 as a Potential Treatment for Rett Syndrome: Safety Assessment in Six Rett Patients, Autism research and treatment , 01/2012, 2012 Journal Article, 2012 DOI

Crotty, D., Silkstone, G., Poddar, S., Ranson, R., Prina-Mello, A., Wilson, M.T., Coey, J.M.D., Erratum: Reexamination of magnetic isotope and field effects on adenosine triphosphate production by creatine kinase (Proceedings of the National Academy of Sciences of the United States of America (2012) 109, 5, (1437-1442) DOI: 10.1073/pnas.1117840108), Proceedings of the National Academy of Sciences of the United States of America, 109, (18), 2012, p7126 Journal Article, 2012 DOI

World Molecular Imaging Congress (WMIC) organising committee, Workshop Nanotechnology in Diagnostics, Monitoring and Treatment of Cancer Advanced in Molecular Imaging within the 5th Annual meeting of the World Molecular Imaging Congress (WMIC), 5-8 Sep 2012, 2012, IMM, Dublin Meetings /Conferences Organised, 2012

Poland, C.A., Byrne, F., Cho, W.S., Prina-Mello, A., Murphy, F.A., Davies, G.L., Coey, J.M., Gounko, Y., Duffin, R., Volkov, Y., Donaldson, K., Lenghth dependent pathogenic effects of nickel nanowires in the lungs and the peritoneal., Nanotoxicology, 2012, p899-911 Journal Article, 2012 DOI

Samuel SP, Jain N, O'Dowd F, Paul T, Kashanin D, Gerard VA, Gun'ko YK, Prina-Mello A, Volkov Y, Multifactorial determinants that govern nanoparticle uptake by human endothelial cells under flow., International journal of nanomedicine, 7, 2012, p2943-56 Journal Article, 2012 TARA - Full Text DOI

Crotty, D., Silkstone, G., Poddar, S., Ranson, R., Prina-Mello, A., Wilson, M.T., Coey, J.M.D., Reexamination of magnetic isotope and field effects on adenosine triphosphate production by creatine kinase (Proceedings of the National Academy of Sciences of the United States of America (2012) 109, 5, (1437-1442) DOI: 10.1073/pnas.1117840108), Proceedings of the National Academy of Sciences of the United States of America, 109, (18), 2012 Journal Article, 2012

Anja Schinwald, Fiona A Murphy, Adriele Prina-Mello, Craig A Poland, Fiona Byrne, Dania Movia, James R Glass, Janet C Dickerson, David A Schultz, Chris E Jeffree, William Macnee, Ken Donaldson, The threshold length for fiber-induced acute pleural inflammation: shedding light on the early events in asbestos-induced mesothelioma, Toxicological Sciences, 128, (2), 2012, p461 - 470 Journal Article, 2012 DOI

Walsh, F., Boyle, N.T., Mardinoglu, A., Chiesa, A.D., Botvich, D., Prina-Mello, A., Balasubramaniam, S., Artificial backbone neuronal network for nano scale sensors, 2011 IEEE Conference on Computer Communications Workshops, INFOCOM WKSHPS 2011, 2011, p449-454 Conference Paper, 2011 DOI

Balasubramaniam, S., Teuscher, C., Botvich, D., Prina Mello, A., Role of Inter-Disciplinary Research in Nanoscale Communication, Nano Communication Networks, Elsevier, Elsevier, 2011 Book, 2011

Special Issue on Role of Inter-Disciplinary Research in Nanoscale Communication , Nano Communication Networks, Elsevier, [eds.], 2011-2012 Editorial Board, 2011 DOI

Knyazev, A., Louise, L., Veber, M., Langevin, D., Filoramo, A., Prina-Mello, A., Campidelli, S, Selective adsorption of proteins on single-wall carbon nanotubes by using a protective surfactant , Chemistry - A European Journal, 17, (51), 2011, p14663 - 14671 Journal Article, 2011 DOI

Murphy, F.A., Poland, C.A., Duffin, R., Al-Jamal, K.T., Ali-Boucetta, H., Nunes, A., Byrne, F., Prina-Mello, A., Volkov, Y., Li, S., Mather, S.J., Bianco, A., Prato, M., MacNee, W., Wallace, W.A., Kostarelos, K., Donaldson, K. , Length-dependent retention of carbon nanotubes in the pleural space of mice initiates sustained inflammation and progressive fibrosis on the parietal pleura , American Journal of Pathology, 178, (6), 2011, p2587 - 2600 Journal Article, 2011 DOI

Mohamed BM, Verma NK, Prina-Mello A, Williams Y, Davies AM, Bakos G, Tormey L, Edwards C, Hanrahan J, Salvati A, Lynch I, Dawson K, Kelleher D, Volkov Y, Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity., Journal of nanobiotechnology, 9, 2011, p29 Journal Article, 2011 DOI

Bashir Mustafa Mohamed, Navin Kumar Verma, Adriele Prina-Mello, Yvonne Williams, Anthony M Davies, Gabor Bakos, Laragh Tormey, Connla Edwards, John Hanrahan, Anna Salvati, Iseult Lynch, Kenneth Dawson, Dermot Kelleher, and Yuri Volkov, Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity, Journal of Nanobiotechnology, 9, 2011, p29- Journal Article, 2011 TARA - Full Text

Walsh, F., Boyle, N.T., Mardinoglu, A., Chiesa, A.D., Botvich, D., Prina-Mello, A., Balasubramaniam, S., Artificial backbone neuronal network for nano scale sensors, 2011 IEEE Conference on Computer Communications Workshops, INFOCOM WKSHPS 2011, 2011, p449-454 Journal Article, 2011 DOI

McGovern, D.A., Daly, R., Prina-Mello, A., Boland, J.J., Porous polymer surfaces as a platform technology for biomaterials, 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials, 2011 Journal Article, 2011

Balasubramaniam, S., Teuscher, C., Botvich, D., Prina Mello, A., Special Issue on Role of Inter-Disciplinary Research in Nanoscale Communication, Nano Communication Networks, 2, (1), 2011, p1-3 Journal Article, 2011 DOI

Movia D, Prina-Mello A, Bazou D, Volkov Y, Giordani S, Screening the Cytotoxicity of Single-Walled Carbon Nanotubes Using Novel 3D Tissue-Mimetic Models., ACS Nano, 5, (11), 2011, p9278-9290 Journal Article, 2011 DOI

McCarthy, J.E.*, Prina-Mello, A.*, Rakovich, T., Volkov, Y., Gun'Ko, Y.K, Fabrication and characterization of multimodal magnetic - Fluorescent polystyrene nanowires as selective cell imaging probes, Journal of Materials Chemistry, 21, (37), 2011, p14129 - 14225 Journal Article, 2011 DOI

RAKOVICH T, PRINA-MELLO A, RAKOVICH A, BYRNE SJ, ATZBERGER A, MCCARTHY JE, GUN'KO YK, VOLKOV Y, APPLICATION OF NANOMATERIALS IN NANOMEDICINE RESEARCH , 2011, 3 , World Scientific , 2011, pp433 - Conference Paper, 2011 DOI

McCarthy, J.E., Gun'Ko, Y.K., Volkov, Y.Rakovich, T., Prina-Mello, A., Rakovich, A., Byrne, S.J., Atzberger, A., , Application of nanomaterials in nanomedicine research, Proceedings of International Conference NANOMEETING 2011: Physics, Chemistry and Applications of Nanostructures - Reviews and Short Notes, NANOMEETING 2011: Physics, Chemistry and Applications of Nanostructures , Minsk; Belarus, 24-27 May, 2011, pp433-436 Conference Paper, 2011

Santos-Martínez MJ, Prina-Mello A, Medina C, Radomski MW., Analysis of platelet function: role of microfluidics and nanodevices., Analyst, 136, (24), 2011, p5120 - 5126 Journal Article, 2011

McGovern, D.A., Daly, R., Prina-Mello, A., Boland, J.J., Porous polymer surfaces as a platform technology for biomaterials, 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials, 2011 Conference Paper, 2011

Sasitharan Balasubramaniam, Noreen T. Boyle, Andrea Della-Chiesa, Frank Walsh, Adil Mardinoglu, Dmitri Botvich, Adriele Prina-Mello, Development of artificial neuronal networks for molecular communication, Nano Communication Networks, 2, (2-3), 2011, p150-160 Journal Article, 2011 TARA - Full Text

Santos-Martinez, M.J., Prina-Mello, A., Medina, C., Radomski, M.W. , Analysis of platelet function: role of microfluidics and nanodevices, Analyst, 136, 2011, p5120 - 5126 Review Article, 2011 DOI TARA - Full Text

Movia, D., Prina-Mello, A. , Volkov, Y. , Giordani, S, Determination of spiropyran cytotoxicity by high content screening and analysis for safe application in bionanosensing, Chemical Research in Toxicology , 23, (9), 2010, p1459 - 1466 Journal Article, 2010 DOI TARA - Full Text

Prina-Mello A., Whelan A.M., Atzberger A., McCarthy J.E., Byrne F., Davies G.L., Coey J.M.D., Volkov Y., Gun'ko Y.K., Comparative Flow Cytometric Analysis of Immunofunctionalized Nanowire and Nanoparticle Signatures, Small, 6, (2), 2010, p247 - 255 Journal Article, 2010 DOI

P.J.Cregg, Kieran Murphy, Adil Mardinoglu, Adriele Prina-Mello, Many particle magnetic dipole-dipole and hydrodynamic interactions in magnetizable stent assisted magnetic drug targeting , Journal of Magnetism and Magnetic Materials, 322, (15), 2010, p2087-2094 Journal Article, 2010 TARA - Full Text DOI

Adil Mardinoglu, P.J. Cregg, Kieran Murphy, Maurice Curtin and Adriele Prina-Mello, Theoretical modelling of physiologically stretched vessel in magnetisable stent assisted magnetic drug targeting application, Journal of Magnetism and Magnetic Materials, 323, (3-4), 2010, p324-329 Journal Article, 2010 TARA - Full Text

Santos-Martinez, MJ, Medina, C, Prina-Mello, A, Conroy, J, Samuels, SP, Volkov, Y, Radomski, MW, A nanoscale resolution assay of flow-induced platelet microaggregation, Kardiochirurgia i Torakochirurgia Polska, 7, (4), 2010, p365-375 Journal Article, 2010 URL

Tian, F., Prina-Mello, A., Estrada, G.G., Beyerle, A., Kreyling, W., Stoeger, T., Cell shape imaging analysis: A fast and reliable technique for the investigation of internalised carbon nanotubes in flat macrophages, Journal of Physics: Conference Series, 151, 2009 Conference Paper, 2009 DOI

Tian, F., Prina-Mello, A., Estrada, G., Beyerle, A., Möller, W., Schulz, H., Kreyling, W., Stoeger, T., Macrophage cellular adaptation, localization and imaging of different size polystyrene particles, Nano Biomedicine and Engineering, 1, (1), 2009, p13-26 Journal Article, 2009 DOI

F Tian, A Prina-Mello, G G Estrada, A Beyerle, W Kreyling and T Stoeger, Cell shape imaging analysis: A fast and reliable technique for the investigation of internalised carbon nanotubes in flat macrophages, Journal of Physics: Conference Series, 151, 2009, p012033 - 012040 Journal Article, 2009 DOI URL

Byrne F., Prina-Mello A., Whelan A., Mohamed B.M., Davies A., Gun'ko Y.K., Coey J.M.D., Volkov Y., High content analysis of the biocompatibility of nickel nanowires , Journal of Magnetism and Magnetic Materials , 321, (10), 2009, p1341-1345 Journal Article, 2009 DOI

Toetsch S, Olwell P, Prina-Mello A, Volkov Y, The evolution of chemotaxis assays from static models to physiologically relevant platforms., Integrative biology : quantitative biosciences from nano to macro, 1, (2), 2009, p170-81 Journal Article, 2009 DOI

Daly R., Boland J.J., Donegan J., Cross G., Prina-Mello A. , Mechanistic insights from formation of novel pore morphologies with breath figure templating. , Proceedings of the 14 th International Conference on Solid Films and Surfaces (ICSFS), 14 th International Conference on Solid Films and Surfaces (ICSFS), Dublin, 2008, 1, ICSFS, 2008, pp143- Conference Paper, 2008

Adriele Prina-Mello, High content screening analysis of proliferating MC3T3-E1 osteoblast cells in contact with nanowires: time dependence toxicological response , 4 th International Conference on Bioengineering and Nanotechnology, UCD, Dublin, July, 2008, Nicholas Abbott and Gill Lee Invited Talk, 2008

Prina-Mello A. , Byrne F., Coey J.M.D.C, Mohamed B.M., Davies A., Volkov Y(ed.), High content screening analysis of proliferating MC3T3-E1 osteoblast cells in contact with nanowires: time dependence toxicological response., Proceedings of the 4 th International Conference on Bioengineering and Nanotechnology, Dublin, 1, July 2008, Nicholas Abbott and Gill Lee, 2008, 15 p Proceedings of a Conference, 2008

Tian F., Prina-Mello A., Estrada G.G., Beyerle A., Möller W., Schulz H., Kreyling W., Stöeger T. , A novel assay for the quantification of internalised nanoparticles in macrophages,, Nanotoxicology, 2, (4), 2008, p232 - 242 Journal Article, 2008 DOI URL

Prina-Mello A. , Daly R., Furlong C., Prendergast P.J., Boland J.J. , Investigation of cell biomimetic and mechano-response to biofunctionalised regular architecture microporous topographies., Proceedings of the 14 th International Conference on Solid Films and Surfaces (ICSFS), . 14 th International Conference on Solid Films and Surfaces (ICSFS), Dublin , edited by ICSF - IOM3 , 1, ICSFS , 2008, pp347- Conference Paper, 2008

Crotty D. Martinez G; Coey J.M.D., Prina-Mello A., Effect of 50Hz, 2mT AC electromagnetic field on proliferation, morphology and CBf-alpha1 protein expression in pre-osteoblast., Proceedings of the 30 th Annual Meeting of the Bioelectromagnetics Society , Bioelectromagnetics Society 30 th Annual Meeting , San Diego, June 2008, edited by BEMS , 1, BEMS, 2008, pp21- Conference Paper, 2008

Byrne F., Prina-Mello A. , Coey J.M.D., Mohamed B.M., Davies A,, Volkov Y. , Interaction of magnetic nickel nanowires with THP-1 cells and high content analysis of their cytotoxic effects. , Proceedings of the Scientific and Clinical Applications of Magnetic Carriers, Scientific and Clinical Applications of Magnetic Carriers, Vancouver, Canada, May 2008, edited by Hafeli, Schutt, Zborowski , 1, Hafeli, Schutt, Zborowski, 2008, pp175- Conference Paper, 2008

Prina-Mello A. , Byrne F., Coey J.M.D., Mohamed B.M., Davies A,, Volkov Y. , Time dependence nanomaterial toxicological response to proliferating MC3T3-E1 osteoblast cells: high content screening analisis. , Proceedings of the th International Conference on Particles, 9 th International Conference on Particles: Risks and Opportunities ., Cape Town, September 2008, edited by Gulumian , 1, Gulumian, 2008, pp50- Poster, 2008

Chun B.S., Walliang A.L., Fermon C, Byrne F., Prina-Mello A. , and J. M. D. Coey., Magnetic label detection in a microfluidic channel., Proceedings of the Joint European Magnetic Symposia, Joint European Magnetic Symposia, Dublin, September 2008, edited by Joint European Magnetic Symposia . , 1, Coey, Sanvito, 2008, ppBM10- Poster, 2008

Prina-Mello A. , Crotty D., Byrne F., Davey G. and J.M.D. Coey. , Cell alignment using a magnetic nanowire and external field gradient. , Proceedings of the Joint European Magnetic Symposia, Joint European Magnetic Symposia , Dublin , September 2008, edited by Joint European Magnetic Symposia , 1, Coey, Sanvito, 2008, ppBM11- Poster, 2008

Daly R., Boland J.J., Donegan J., Cross G., Prina-Mello A. , Mechanistic insights from formation of novel pore morphologies with breath figure templating. , MRS annual proceedings, Materials Research Society (MRS) Annual Conference, Boston. MA, USA, December 2007, edited by Institute of Materials, Minerals and Mining (IOM3) , (1), Institute of Materials, Minerals and Mining (IOM3), 2007, ppff4.4- Conference Paper, 2007

Crotty D., Morgan J.P., Coey J.M.D., and A. Prina-Mello. (ed.), Osteoblast cell response to external stimulation after internalization of nickel nanowires. , Proceedings of the 13 th Bioengineering Ireland. The School of Mechanical and Aerospace Engineering, Belfast, ISBN 1-905254-18-0, 2007, Queen's University Belfast, 2007 Proceedings of a Conference, 2007

Prina-Mello A, Farrell E, Prendergast PJ, Campbell V, Coey JMD , Influence of strong static magnetic fields on primary cortical neurons , Bioelectromechanics, 27, 1, (Jan), 2006, p35 - 42 Journal Article, 2006

A. Prina-Mello, Z. Diao, and J.M.D. Coey, Nano-scale cell manipulation by magnetic field in the presence of functionalised magnetic carriers, Proceedings of Bioengineering in Ireland 12, Bioengineering in Ireland 12, Ireland, 27-28 January 2006, edited by McHugh, O'Mahony, Fitzpatrick , ISBN 1 905 254 075, The National Centre for Biomedical Engineering Science, 2006, pp73 - 74 Conference Paper, 2006

A. Prina-Mello, Z. Diao, and J.M.D. CoeyA. Prina-Mello, Z. Diao, and J.M.D. Coey, Multilineage cell alignment and separation by magnetic field after internalization of nickel nanowires., Proceedings of the Scientific and Clinical Applications of Magnetic Carriers, Scientific and Clinical Applications of Magnetic Carriers, Austria, May 2006, edited by Hafeli, Schutt, Zborowski , 2006, pp41 - 42 Conference Paper, 2006

A. Prina-Mello, Z. Diao and J.M.D. Coey, Internalization of ferromagnetic nanowires by different living cells, Journal of Nanobiotechnology, 4, (9), 2006, p1 - 11 Journal Article, 2006 DOI URL TARA - Full Text

Prina-Mello A., Farrell E., Prendergast P.J., Campbell V., Coey J.M.D. , Influence of Strong Static Magnetic Fields on Primary Cortical Neurons, Bioelectromagnetics, 27, (1), 2006, p35 - 42 Journal Article, 2006 DOI URL

A. Prina-Mello, Z. Diao, and J.M.D. Coey, Osteoblast cell alignment by magnetic field after internalization of nickel nanowires, Proceeedings of the International Conference on Magnetism 06 , International Conference on Magnetism 06 , Kyoto, 20-25 August 2006, edited by ICM06 Editor committee , ICM06 - Publishers, 2006, pp64 - 64 Conference Paper, 2006

Serena A Corr, Aisling O'Byrne, Yurii K Gun'ko, Swapankumar Ghosh, Dermot F Brougham, Siobhan Mitchell, Yuri Volkov, Adriele Prina-Mello, Magnetic-fluorescent nanocomposites for biomedical multitasking, Magnetic-fluorescent nanocomposites for biomedical multitasking. Chemical Communications, (43), 2006, p4474 - 4476 Journal Article, 2006

A. Prina-Mello, Z. Diao and J.M.D. Coey, Cell Separation and Manipulation by magnetic field in the presence of functionalised magnetic nanowires., Proceedings of NSTI Nanotech 2006 - BIONANO 2006, NSTI Nanotech 2006, Boston, USA, May 2006, edited by Ed. Laudon and Romanowicz , 1, (ISBN: 0-9767985-6-5), 2006, pp62 - 63 Conference Paper, 2006

Serena A. Corr, Aisling O' Byrne, Yurii K. Gun'ko, Swapankumar Ghosh, Dermot F. Brougham, Siobhan Mitchell, Yuri Volkov and Adriele Prina-Mello, Magnetic-fluorescent nanocomposites for biomedical multitasking, Chemical Communications, 43, 2006, p4474 - 4476 Journal Article, 2006 URL DOI

Prina-Mello A, Farrell E, Prendergast PJ, Campbell V, Coey JMD, Influence of Strong Static Magnetic, Bioelectromagnetics, 27, (1), 2006, p35 - 42 Journal Article, 2006 URL

Corr SA, O'Byrne A, Gun'ko YK, Ghosh S, Brougham DF, Mitchell S, Volkov Y, Prina-Mello A, Magnetic-fluorescent nanocomposites for biomedical multitasking., Chemical communications (Cambridge, England), (43), 2006, p4474-6 Journal Article, 2006

Prina-Mello A. , Volkov Y., and Prendergast P.J., Effect of microtopography and cell concentration on T lymphoid cell migration during in vitro extravasation process, NSTI Nanotech 2005, Anaheim, CA, May 2005, edited by NSTI , NSTI, 2005 Conference Paper, 2005 URL

Prina_Mello A., Bioelectromagnetics 2005. Joint meeting of the American and European society of Bioelectromagnetics, 19-24 June, 2005, Dublin, (Sp 2005), 1, Bioelectromagnetics Meetings /Conferences Organised, 2005 URL

Prina_Mello A. , Campbell V., and Coey J.M.D. , Static magnetic field effect in cells. A possible roa to cell differentiation., NSTI Nanotech 2005 , Anaheim, CA, May 2005, edited by NSTI , NSTI, 2005 Conference Paper, 2005

Prina_Mello, A, Farrell, E, Prendergast, PJ, Campbell, V, Coey, JMD, Effects of static magnetic fields on Primary cortical neurons, Physica Scripta, T118, 2005, p205 - 207 Journal Article, 2005 URL DOI

Moretti, M, Barron, V, Prina Mello, A, Reid, AJ, Prendergast, PJ, Endothelial cell alignment on cyclically-stretched silicone surfaces, Journal of Materials Science: Materials in Medicine, 15, 2004, p1159 - 1164 Journal Article, 2004 DOI

The state-of-the-art in cartilage bioreactors. in, editor(s)PJ Prendergast, PE McHugh , Topics in Bio-Mechanical Engineering, Dublin, Trinity Centre for Bioengineering & National Centre for Biomedical Engineering Science, 2004, pp94 - 146, [McMahon LA, Barron V, Prina-Mello A, Prendergast PJ ] Book Chapter, 2004

Moretti M., Prina_Mello A., Reid A.J., Barron V., Prendergast P.J. 2004. , Endothelial cell alignment on cyclically-stretched silicone surfaces., Journal of Materials Science: Materials in Medicine , 15, (10), 2004, p1159 - 1164 Journal Article, 2004 DOI URL

Long A, Mitchell S, Kashanin D, Williams V, Prina Mello A, Shvets I, Kelleher D, Volkov Y., A multidisciplinary approach to the study of T cell migration, Annals of the New York Academy of Sciences, 1028, 2004, p313 - 319 Journal Article, 2004

A multidisciplinary approach to the study of T cell migration in, editor(s)Bradlow H.L., Castagnetta L., Massimo L., Zaenker K. , signal transduction and communication in cancer cells, New York, New York Academy of Sciences, 2004, pp313 - 319, [Long A., Mitchell S., Kashanin D., Williams V., Prina-Mello A., Shvets I.V., Kelleher D., Volkov Y.] Book Chapter, 2004 URL

Long, A., Mitchell, S., Kashanin, D., Williams, V., Mello, A.P., Shvets, I., Kelleher, D., Volkov, Y., A Multidisciplinary Approach to the Study of T Cell Migration, Annals of the New York Academy of Sciences, 1028, 2004, p313 - 319 Journal Article, 2004 URL DOI

Prina-Mello A., Volkov Y., Kelleher D., Prendergast P.J., Comparative locomotory behaviour of T Lymphocytes versus T Lymphoma cells on flat and grooved surfaces., Annals of Biomedical Engineering. , 31, 2003, p1106 - 1113 Journal Article, 2003 DOI

Prina_Mello A., Volkov Y., Prendergast P.J. , Experimental analysis on normal and malignant lymphocytes under topographical environments using a single-cell method. , Acta of Bioengineering and Biomechanics., European Society of Biomechanics, Wrozlaw, Poland, 1 , (4), 2003, pp186 - 187 Conference Paper, 2003

Prina_Mello A., Volkov Y., Prendergast P.J. , Experimental analysis on normal and malignant lymphatic cells under topographical environments using a single-cell motion method., Proceedings of the IVth World Congress of Biomechanics., IVth World Congress of Biomechanics., Calgary (Canada), June 2002, 2002, ppCD-ROM proceedings Conference Paper, 2002

Mello, AP, Bari, MA, Prendergast, PJ, A comparison of excimer laser etching and dry etching process for surface fabrication of biomaterials, Journal of Materials Processing Technology, 124, 2002, p284 - 292 Journal Article, 2002

Prina_Mello A., Bari M.A. Prendergast, P.J. , A comparison of excimer laser etching and dry etching process for surface fabrication of biomaterials., Journal of Materials Processing Technology , 124, 2002, p284 - 292 Journal Article, 2002 URL

Prina-Mello A., Prendergast P.J., Volkov Y., T lymphatic cells response to microtextured surfaces: difference between HUT78 and PBTL cells, 5th International Conference in Cellular Engineering., Aachen, Germany, 2001, ppst_17 Conference Paper, 2001

Prina_Mello A., Prendergast P.J., Moretti M., Volkov Y. , Mechanical constraint of lymphatic cells: experimental analysis and model., Proceedings of the 15th AIMETA Congress of Theoretical and Applied Mechanics, , Taormina, Italy, 2001, ppMS_BIO_04. Conference Paper, 2001

Taylor D, O'Brien F, Prina-Mello A, Ryan C, O'Reilly P, Lee TC , Compression data on bovine bone confirms that a "stressed volume" principle explains the variability of fatigue strength results. , Journal of Biomechanics, 32, (11), 1999, p1199 - 1203 Journal Article, 1999 DOI URL

Non-Peer-Reviewed Publications

Adriele Prina-Mello, The importance of preclinical testing: consideration on model relevance for testing innovation, The 9th workshop NANOMED - Nano drug delivery for immunotherapy, Pavia, Italy, 22-24 July 2026, 2026, NANOMED EMJMD committee and Univeristy of Pavia Invited Talk, 2026 URL

Adriele Prina-Mello, Advanced Medical Technologies: from concept to product, Advanced Biomaterials-based Technologies: from concept to product, Polytechnic of Turin, 1-3 July 2026, 2026 Invited Talk, 2026 URL

Adriele Prina-Mello, Translational approaches for Advanced therapy medicinal products, NANOMED Summer School 2026: SS Medicinal tissue engineering, University of Pavia, Pavia, Italy, 20-22 Jul 2026, 2026 Oral Presentation, 2026 URL

Adriele Prina-Mello, Medical Devices Regulatory requirements for in vitro testing, INJECTHEAL Project Wound Healing workshop, JOANNEUM RESEARCH COREMED/HEALTH, 22.01.2026, 2026, INJECTHEAL Project and JOANNEUM RESEARCH Invited Talk, 2026

Adriele Prina-Mello, How to make a Research Institute sustainable, Translational Medicine Conference 2026, Trinity Translational Medicine Institute (TTMI), 27th Mar 2026, 2026 Oral Presentation, 2026 URL

Adriele Prina-Mello, Translational approach required for the development of the next generation of medical devices, TEN4CARE NANOMED Summer School 2026: Medicinal and Tissue engineering, University of Pavia, 20-22 July 2026, 2026, TEN4CARE project consortium and University of Pavia committee Invited Talk, 2026 URL

Costanza Di Marco, Sarah Kennedy, Sophia Khan, Matteo Santin, Adriele Prina Mello, Preliminary safety evaluation of an ECM-mimetic basement membrane as possible modulator in chronic wounds microenvironment, Tissue & Cell Engineering Society Conference, Huxley Building, Moulsecoomb Campus, Brighton, 15-17 Jun 2026, 2026 Poster, 2026 URL

Adriele Prina-Mello, 'Nanomedicine and Magnetic Hyperthermia', Breakthrough Cancer Exhibition: Cancer Revolution: Science, Innovation and Hope, Stephen"s Green Shopping Centre, Dublin, Breakthrough Cancer Research organisation, 2025, - Exhibition, 2025 URL

Adriele Prina-Mello, Translational approach for nanomedicines, Nanomedicine Elective module a.y 25/26, St. Caterina College, Pavia (Italy), 1-5 Dec 2025, 2025, St. Caterina College, Pavia (Italy) Invited Talk, 2025

Tecla Simone and Adriele Prina-Mello, In vitro spheroid-based Non-Small Cell Lung Cancer angiogenic pre-clinical model for advancing the development of effective cancer therapeutics, Goodbye Flat Biology 2025: ex vivo to in vivo models of cancer, Essen, Germany, 23-25 Sep 2025, 2025 Poster, 2025 URL

Adriele Prina-Mello, How to promote innovation: TCD experience of European Funding opportunities, European Research Council INPACT! work group workshop on innovation, Online, 25 Mar 2025, 2025, INPACT! workgroup Invited Talk, 2025

Adriele Prina-Mello, EXPERT workshop Unlocking the Potential of mRNA, 4th mRNA-Based Therapeutics Summit Europe, Sheraton Frankfurt Airport Hotel and Conference Center, (Germany), 28 Jan 2025, 2025, Hanson Wade Invited Talk, 2025

Adriele Prina-Mello, TTMI Sustainability: How to make a Research Institute sustainable, TTMI Conference 2025, TTMI, TCD, 28 Mar 2025, 2025, TTMI committee Invited Talk, 2025

Melissa Anne Tutty, Adriele Prina-Mello, Advanced 3D Liver Models as in vitro alternatives for the pre-clinical assessment of mRNA-LNP- based Cancer Immunotherapies, Goodbye Flat Biology 2025: ex vivo to in vivo models of cancer, Essen, Germany, 23-25 Sep 2025, 2025 Poster, 2025 URL

Melissa Anne Tutty, Adriele Prina-Mello, The Application of 3D Hepatic Spheroids in the Development of a NanoBioMaterial-specific Alkaline Comet Assay for Genotoxicity Screening, Nanotox 2024, Venice, Italy, 23 - 25 Sep 2024, 2024 Oral Presentation, 2024 URL

Adriele Prina-Mello, Characterization of nanoparticles in view of the regulatory Marketing Authorization Application, Seminar series on Industrial Biotechnology and Pharmaceutical Technologies, Department of Drug Sciences, Pharmacology, Pavia, (Italy), 2-3 Dec 2024, 2024, University of Pavia Invited Talk, 2024

Melissa Anne Tutty, Tecla Simone, Adriele Prina-Mello, Development of an Advanced 3D Model for the Clinical Translation Screening of Advanced Materials, ETPN 2024 Conference, Milan, Italy, 10-12 Jun 2024, 2024 Poster, 2024 URL

Adriele Prina-Mello, Adrielel Prina-MelloHands-on Workshop "Biomedical research in action" for primary school, 2024, - Miscellaneous, 2024

Adriele Prina-Mello, Lipid Nanoparticle technology for future Cancer Therapeutics, The importance of Quality by Design as pre-clinical tool for translational success, Seminar Maynooth University, Maynooth University, 22nd Nov 2024, 2024 Invited Talk, 2024

Adriele Prina-Mello, Translational approaches for Nanomedicines and Medical Technology into innovative product, The International Standardisation Roadmap for Nanomedicine, Regulatory and Metrology workshop, French National Metrology Institute (LNE), Paris, (France), 13th Nov 2023, 2023 Invited Talk, 2023 URL

Adriele Prina-Mello, Iron Oxide Nanoparticles intended for Magnetic Hyperthermia: A Translational Story, Seminar at the University of Tartu (Estonia), University of Tartu (Estonia), 2 Mar 2023, 2023 Invited Talk, 2023

Safe-N-MedTech project - clinical committee, Workshop on Hyperthermic Oncology, 9 jun 2023, 2023, Hotel Front Maritim, Barcelona, (Spain) Meetings /Conferences Organised, 2023

Adriele Prina-Mello, NanoGagliato 2022, 27-30 Jul 2022, 2022, Academia di Gagliato, Gagliato (Italy) Meetings /Conferences Organised, 2022 URL

Joint ETPN with Spanish organising committee, NANO WORLD CANCER DAY 2022, 2022, Online Meetings /Conferences Organised, 2022

Adriele Prina-Mello, Preclinical challenges in upscaling of a nanotherapy for early clinical phases of pancreatic cancer, Nanoparticle-based approaches towards the clinic NoCanTher & SafeNMedtech joint worshop, IMDEA Nanocienca, Madrid, Spain, 17 May 2022, 2022 Invited Talk, 2022

Adriele Prina-Mello, Integrated Risk Management (IRM) Framework for risk management of engineered biomaterials in Advanced Therapy Medicinal Products (ATPM) and Medical Devices (MD), BioNanoNet Annual Forum and BNN Networking Session 2021, Gratz, Austria, 16 Sep 2021, 2021, BNN Invited Talk, 2021 URL

Melissa Anne Tutty, Adriele Prina-Mello, The development of a HepG2 3D spheroid model for the preclinical assessment of nanobiomaterials (NBMs)., Nanotox 2021 conference, Virtual conference, 20 - 22 Apr 2021, 2021 Poster, 2021

Adriele Prina-Mello and Academia di Gagliato, NanoGagliato 2021, 27-31 Jul 2021, 2021, Academia di Gagliato, Gagliato (Italy), Chair, Session organiser, Rapporteur Meetings /Conferences Organised, 2021

Anna Bogdanska, Oliviero L. Gobbo, Yuri Volkov and Adriele Prina-Mello, Adapting histology methods to nanoparticle research; from detection to 3D histology volumes, NanoTox2021 virtual conference, 2021 Oral Presentation, 2021

Anna Bogdanska, Oliviero GobboA and Adriele Prina-Mello, 3D histology volumes; an innovative tool for assessment of biodistribution and aggregation of SPIONs in vivo, NanoTech Poland meeting, 2021 Oral Presentation, 2021

Melissa Anne Tutty, Gavin McManus, Dania Movia, Adriele Prina Mello, Assessing morphology, functionality and health of HepG2 3D spheroids for the preclinical assessment of nanobiomaterials for cancer applications., Microscopy Society Ireland Symposium 2020, Trinity Biomedical Sciences Institute, Trinity College Dublin, Ireland., 8th January 2020, , 2020 Poster, 2020

Adriele Prina-Mello and REFINE project organising committee, REFINE 2nd conference on regulation of Nanomedicines, 2-3 Nov 2020, 2020, -conference online (virtual) Meetings /Conferences Organised, 2020

Adriele Prina-Mello, Transparency, Reproducibility and Translation of Nanomedicine! Tackling the Complexity, CLINAM European Foundation for Clinical Nanomedicine Virtual Summit, Virtual conference, 27-29 Oct 2020, 2020 Invited Talk, 2020 URL

Adriele Prina-Mello and NANOMED Europe 2019 organising committee, NANOMED Europe 2019, 17-19 Jun 20219, 2019, INL, Braga (Portugal) Meetings /Conferences Organised, 2019

Villella E, Bogdanska A, Sasse A, Prina-Mello A, Gobbo OL, Superparamagnetic Iron Oxide Nanoparticles for Cancer Hyperthermia Treatment Histological Assessment of Biodistribution and Clearance, All Ireland Schools of Pharmacy conference,, 2019 Poster, 2019

NANOMED 2018, NANOMED workshop, 3-4 Dec 2018, In:NANOMED workshop, 2018, Pavia, Italy Meetings /Conferences Organised, 2018

Adriele Prina-Mello and ETPN NWCD organising committee, NANO WORLD CANCER DAY 2018, 2 Feb 2018, 2018, Virtual event (online) Meetings /Conferences Organised, 2018

Adriele Prina-Mello, Characterization in nanomedicine: Lesson learnt from the EUNCL (European Nanomedicine Characterisation Laboratory) and REFINE Project., 3rd Italian-Swedish Workshop on NanoBioMaterials - From safety assessment to biomedical uses, Turin (Italy), 22-23 Mar 2018, 2018 Oral Presentation, 2018

Adriele Prina-Mello, Development of liver 3D model as alternative to animals, Trinity Translational Medicine Institute Seminar, TTMI, TCD Dublin, 24 Apr 2018, 2018 Oral Presentation, 2018

Adriele Prina-Mello, NANOWOW 6 weeks course, May to June 2018, In:NANOWOW 6 weeks course, 2018, Dublin Meetings /Conferences Organised, 2018

Joint ETPN and local organising committees, NANO WORLD CANCER DAY 2017, 2 Feb 2017, 2017, IMM, Dublin, Ireland and Global (online) Meetings /Conferences Organised, 2017

Adriele Prina-Mello, TCD joint work toward First In Man: Advanced translational work, NANOGAGLIATO 2017, Gagliato (Italy), 25 Jul 2017, 2017 Oral Presentation, 2017

TTMI Seminar, TTMI seminar: Nanomedicine series, 14 Feb 2017, 2017, TTMI, TCD Meetings /Conferences Organised, 2017

Adriele Prina-Mello, Charles University delegation visit to TCD, 6-7 Nov 2017, In:Charles University, Faculty of Medicine in Hradec Kralove, 2017, Dublin Meetings /Conferences Organised, 2017

Joint ETPN and local organsing committees, NANO WORLD CANCER DAY 2016, 2 Feb 2016, 2016, IMM, Dublin, Ireland and Global (online) Meetings /Conferences Organised, 2016

Adriele Prina-Mello, Nanosafety: The interface between industry, authorities and safety researchers, NETWORKING EVENT to ADVANCE NANOSAFETY in NORWAY , Oslo, 15.09.2016, 2016 Oral Presentation, 2016

Adriele Prina-Mello, Nanotechnology for cancer diagnostics , Cytometry Society of Ireland, TBSI, TCD, Dublin, 8 Nov 2016, 2016 Oral Presentation, 2016

Adriele Prina-Mello, NANOMATERIALS in MEDICINE: Structural And Physical-chemical aspects, Special NANO-Course-1 Nanomaterials, Nanotoxicology and Immunomodulation by Nanoparticles, Kazan, Russia, 14-17 Nov 2016, 2016 Oral Presentation, 2016

Susan Dekkers, Agnes G Oomen, Eric AJ Bleeker, Rob J Vandebriel, Christian Micheletti, Joan Cabellos, Gemma Janer, Natalia Fuentes, Socorro Vázquez-Campos, Teresa Borges, Maria João Silva, Adriele Prina-Mello, Dania Movia, Fabrice Nesslany, Ana Ribeiro, Paulo Emílio Leite, Monique Groenewold, Flemming R Cassee, Adrienne JAM Sips, Aart Dijkzeul, Tom van Teunenbroek, Susan WP Wijnhoven, NANoREG Deliverable D 5.8-Decision tree for risk assessment of MNMs , 2016 Report, 2016

Adriele Prina-Mello, MULTIFUNCTIONAL NANOMATERIALS: Regulatory aspects and safe-by-design approach, Special NANO-Course-1 Nanomaterials, Nanotoxicology and Immunomodulation by Nanoparticles, Kazan, Russia, 14-17 Nov 2016, 2016 Oral Presentation, 2016

Adriele Prina-Mello, Exosome and Extracellular Vesicle Characterisation using Nanoparticle Tracking Analysis, NUIG REMEDI seminar, Galway, 1 dec 2016, 2016 Oral Presentation, 2016

Multifun project organising committee, MULTIFUN Final Workshop, 23-25 Feb 2015, 2015, IMDEA, Madrid Spain Meetings /Conferences Organised, 2015 URL

Joint ETPN and local organising committee, NANO WORLD CANCER DAY 2015, 4 Feb 2015, 2015, IMM, Dublin, Ireland and Global (online) Meetings /Conferences Organised, 2015

Prina-Mello A. , MULTIFUN Dissemination Booklet, TCD , Trinity College Dublin Publisher, 2014 Book, 2014 URL

Prina-Mello A. and NAMDIATREAM consortium, NAMDIATREAM Dissemination Booklet, TCD, Trinity College Dublin Publisher, 2014 Book, 2014

Shortt CM, Edge D, Teughels S, Roskin E, Verbiest J, Gobbo OL, Prina-Mello A, Volkov Y, Markos F (, Bio-distribution of superparamagnetic iron oxide nanoparticles (SPION"s) in the pig" Experimental Biology, FASEB, 2014 Poster, 2014

Adriele Prina-Mello, ETPN Strategic Research and Innovation towards 2020, EURONANOMED II Workshop, Düsseldorf, Germany, 29th Jan 2014, 2014, Euronanomed II project Invited Talk, 2014 URL

ETPN and Local organising committee, NANO WORLD CANCER DAY 2014, 3 Ffeb 2014, 2014, IMM, TCD Dublin and Global (online) Meetings /Conferences Organised, 2014 URL

IMM conference organising committee, Institute of Molecular Medicine, 17th Annual Meeting focusing on cancer, infection, and immunology, 12 Jan 2014, 2014, IMM, TCD Meetings /Conferences Organised, 2014

Adriele Prina-Mello and ETPN NWCD organisers, NANO WORLD CANCER DAY 2013 (first edition), 4 Feb 2013, 2013, TCD and online Meetings /Conferences Organised, 2013

University Medical Centre of Gottingen organising committee, Translational Oncology for novel nanoparticle-based diagnostic toolkits, 13 Jun 20913, 2013, University Medical Centre, Gottingen, Germany Meetings /Conferences Organised, 2013 URL

EuroNanoForum European and local organising committee, Workshop Nanomedicine: Technology Platforms and Breakthrough Projects at Euronanoforum 2013, 18-20 Jun 2013, 2013, Euronanoforum 2013, Convention Centre, DublinOrganising committee, Session Chair for nanodiagnostics Meetings /Conferences Organised, 2013 URL

Adriele Prina-Mello, Yuri Volkov, Nanotechnology in Diagnostic, Monitoring and Treatment of Cancer Advanced in Molecular Imaging , 5-8 September 2012, In:World Molecular Imaging Congress 2012, 2012, Dublin, WMIS Meetings /Conferences Organised, 2012 URL

Santos-Martinez, M.J., Medina, C., Prina-Mello, A., Conroy, J., Samuels, S.P., Volkov, Y., Radomski, M.W., Nanobalance: a novel method for the measurement of flow-induced platelet aggregation, Nanomedicine: Seminar and Workshop, Centre for Research on Nanostructures and Nanodevices Trinity College Dublin, 29 June 2009, 2009 Poster, 2009

Coey, Sanvito, Joint European Magnetic Symposia , 2008, In:Joint European Magnetic Symposia , 2008, Dublin , 1, Proceedings of the Joint European Magnetic Symposia Meetings /Conferences Organised, 2008

Prina-Mello A. , Byrne F., Whelan A., Mohamed B.M., Davies A., Gun'Ko Y., Coey J.M.D., Volkov Y. (ed.), Conference on Nanotechnology: implications for human health, the environment and food safety, Proceedings of the IST 2007 Conference on Nanotechnology, Dublin, 1, November 2007, DIT - Focas institute, 2007 Proceedings of a Conference, 2007

A. Prina-Mello, Cell manipulation by magnetic field in the presence of functionalised magnetic nanowires , Nanotechnology seminar, MIT-Harvard University, Langer's La, Boston, USA, 10th May 2006, 2006, Dr. Lisa Freed Invited Talk, 2006

A. Prina-Mello, Magneto-biology at the SFI Trinity Nanoscience Laboratory, Department of Bioimaging and Bioengineering - Tokyo University, February 10th 2006, 2006, Prof. Shoogo Ueno Invited Talk, 2006

Prina_Mello A. , Trinity Bioelectromagnetics Seminar, 21 June, 2005, TCD, Dublin Meetings /Conferences Organised, 2005

Buckley C.T., Prina-Mello A., O'Kelly K.U., Development of biodegradable elastomeric scaffolds for mechanobiology investigations, Proceedings of the 11th Annual Conference of the Section of Bio-engineering of the Royal Academy of Medicine in Ireland, Galway, edited by FitzPatrick D.P. and Senouci M. , 2005, pp13- Oral Presentation, 2005

Research Expertise

Description

My research programme sits at the translational core of nanomedicine, bridging nanomaterial engineering, biological characterisation, and clinical application, evidenced by a Google Scholar record of over 11,000 citations and an h-index of 56 (Scopus 49, Web of Science 46), and by election as a Fellow of Trinity College Dublin (2021). As Founder and Director of the Laboratory for Biological Characterization of Advanced Materials (LBCAM), the Irish node of the European Nanomedicine Characterisation Laboratory (EU-NCL), I have built critical translational infrastructure for nanomedicine in Europe, reinforced by leadership roles across twelve EC-funded consortia (including EU-NCL, REFINE, Safe-N-MedTech and NoCanTher), through which I have supported translation of eight technology platforms from bench to bedside since 2011. This trajectory has now matured into a first-in-human clinical investigation: the EU-funded NanoPanther project (approved Aug 2026), built directly on my magnetic-hyperthermia and nanoparticle-safety research, is progressing to multisite clinical investigation for pancreatic cancer treatment. My publication record substantiates deep expertise in preclinical nanomaterial safety, imaging and regulatory science, from immunotoxicity of oncology nanomedicines (Hannon et al., Advanced Science, 2019) to the 2024 international nanomedicine standardisation roadmap I co-authored (Drug Delivery and Translational Research), reflecting my ETPN Characterization and Toxicology working-group chairmanship. Collectively, this portfolio unites nanomaterial science, biological safety assessment, and regulatory translation into a coherent, high-impact trajectory, the interdisciplinary, internationally engaged research profile driving nanomedicine from laboratory innovation into clinical and regulatory reality.

Projects

  • Title
    • SAFETY TESTING IN THE LIFE CYCLE OF NANOTECHNOLOGY-ENABLED MEDICAL TECHNOLOGIES FOR HEALTH
  • Summary
    • SAFE-N-MEDTECH will build an innovative open access platform to offer companies and reference laboratories, the capabilities, knowhow, networks and services required for the development, testing, assessment, upscaling and market exploitation of nanotechnology-based Medical and Diagnosis Devices. This across the whole Life Cycle of nano-enabled MTs.
  • Funding Agency
    • European Union
  • Date From
    • 1 April 2019
  • Date To
    • 31 Mar 2023
  • Title
    • EXpanding Platforms for Efficacious mRNA Therapeutics
  • Summary
    • EXPERT is to create an off-the-shelf mRNA-delivering nanomedicine platform that is manufactured via a quality-by-design approach that meet the requirements for GMP scaling up and clinical translation.
  • Funding Agency
    • European Union
  • Date From
    • 1 Jun 2019
  • Date To
    • 31 may 2023
  • Title
    • Regulatory Science Framework for Nano(bio)material-based Medical Products and Devices
  • Summary
    • REFINE proposes a Regulatory Science Framework for the risk-benefit assessment of medical products and medical devices that are based on nanomedicines and biomaterials. The heart of our framework is the development of a product-specific Decision Support System that identifies the most efficient way to deliver the data required by regulation by the best-fitting methods. The decision tree will explicate the product's specific regulatory challenges and the priorities of both missing data and missing methods to match these challenges. It will thus allow planning a cost-and time efficient strategy both for necessary measurements and for the advancement of methods. Our approach is aligned with the industrial R&D practice of stage gating.
  • Funding Agency
    • European Union
  • Date From
    • 2017
  • Date To
    • 2021
  • Title
    • European Nanomedicine Characterisation Laboratory
  • Summary
    • To provide a trans-disciplinary testing infrastructure covering a comprehensive set of preclinical characterisation assays (physical, chemical, in-vitro and in-vivo biological testing) allowing researchers to fully comprehend the bio distribution, metabolism, pharmacokinetics, safety profiles and immunological effects of their Med-NPs.
  • Funding Agency
    • European Union
  • Date From
    • 2016
  • Date To
    • 2019
  • Title
    • Risk Management of Biomaterials
  • Summary
    • BIORIMA aims to develop an Integrated Risk Management (IRM) framework for NBM used in ATMP and MD. The BIORIMA IRM framework is a structure upon which the validated tools and methods for materials, exposure, hazard and risk identification/assessment and management are allocated plus a rationale for selecting and using them to manage and reduce the risk for specific NBM used in ATMP and MD.
  • Funding Agency
    • European Union
  • Date From
    • 2017
  • Date To
    • 2021
  • Title
    • NOCANTHER
  • Summary
    • Nanomedicine upscaling for early clinical phases of multimodal cancer therapy
  • Funding Agency
    • European Union
  • Date From
    • 2016
  • Date To
    • 2021
  • Title
    • NANOREG
  • Summary
    • The NANoREG project will establish a better level of trust between industry and policy developers and also establish a new, demand driven approach, involving the interaction of material specialists and nano-toxicologists. This will help to establish trust between the main players, namely regulators, scientific community and industry. With this project we will get not only a better coordination of the EU research agenda regarding the reduction of risk of nano materials, but improved or more focused interaction between industry, regulators and the scientific community.
  • Funding Agency
    • European Commission
  • Date From
    • 1/03/2013
  • Date To
    • 28/02/2017
  • Title
    • Amber centre Horizontal Platform
  • Summary
    • Horizontal Platform in Environmental Health and Safety (EHS) assessment of manufactured materials.
  • Funding Agency
    • Science Foundation Ireland
  • Date From
    • 2013
  • Date To
    • 2018
  • Title
    • AMCARE FP7 project
  • Summary
    • AMCARE is a translational research program to develop advanced multimodal regenerative therapies using cardiopoeitic stem cells and smart biomaterials that effectively treat damage caused by acute myocardial infarction.
  • Funding Agency
    • European Commission
  • Date From
    • 1/11/14
  • Date To
    • 30/10/18
  • Title
    • IRC Postgraduate
  • Summary
    • Assessing the potential of nanomedicine to improve the diagnosis and treatment of pancreatic cancer
  • Funding Agency
    • Irish Research Council
  • Date From
    • 1/10/2016
  • Date To
    • 31/09/2019
  • Title
    • INEDITED
  • Funding Agency
    • Irish Research Council (IRC)
  • Date From
    • 1/10/2015
  • Date To
    • 31/09/2017
  • Title
    • MULTIFUN
  • Summary
    • The MULTIFUN consortium focuses on the development and validation of new systems based upon minimal invasive nanotechnology for the early and selective detection and elimination of breast and pancreatic cancer with reduced side effects. The project will deploy a strategy based on the multifuntionalisation of magnetic iron oxide nanoparticles (MNP), combining diagnostic and therapeutic features against breast and pancreatic cancer and cancer stem cells.
  • Funding Agency
    • European Commission
  • Date From
    • 13/6/2011
  • Date To
    • 12/6/2015
  • Title
    • NAMDIATREAM (EU-FP7-NMP LA)
  • Summary
    • NAMDIATREAM will develop nanotechnology-based toolkit to enable early detection and imaging of molecular biomarkers of the most common cancer types and of cancer metastases, as well as permitting the identification of cells indicative of early-stage disease onset. The project is built on the innovative technology concepts of super-sensitive "lab-on-a-bead", "lab-on-a-chip" and "lab-on-a-wire" nano-devices. Namdiatream is an interdisciplinary and Pan-european consortium that builds around 7 High-Tech SMEs, 2 Multinational industries and 13 academic institutions.
  • Funding Agency
    • EU FP7
  • Date From
    • 1/07/2010
  • Date To
    • 30/06/2014
  • Title
    • Quality NANO
  • Summary
    • QualityNano is a Research Infrastructure for nanosafety assessment. QualityNano's core aim is the creation of a 'neutral' scientific & technical space in which all stakeholder groups can engage, develop, and share scientific best practice in the field. Initially it will harness resources from across Europe and develop efficient, transparent and effective processes. Thereby it will enable provision of services to its users, and the broader community, all in the context of a best-practice ethos. This will encourage evidence-based dialogue to prosper between all stakeholders. However, QualityNano will also pro-actively seek to drive, develop and promote the highest quality research and practices via its Joint Research Activities (JRA), Networking Activities (NA) and provision of Transnational Access (TA) functions, with a global perspective and mode of implementation.
  • Funding Agency
    • European Commission
  • Date From
    • 1/02/11
  • Date To
    • 31/01/15
  • Title
    • Barcode project
  • Funding Agency
    • SFI
  • Date From
    • 1/09/2007
  • Date To
    • 31/12/2009

Keywords

Bioelectromagnetism; Bioengineering; Biomagnetism; Biomaterials; Biomechanics; Biomechanics, Biomedical Engineering; Biomedical Engineering; Biomedical sciences; Biophysics; Bioreactors; Biosensors; Biotechnology; Cell and tissue development; Cell Communication; Cytoskelton, cell division; Intra and intercellular signalling; Mechanical Engineering; Medical Devices Engineering; Microelectronics technology; Multisensory technology, multi sensing; Nano Biotechnology; Nano-Materials; Nanochemistry; NanoMedicine; Nanotechnology; Neurobiology; Stem Cell biology and hematopoiesis; Surface and interface physics; Tissue Culture

Recognition

Representations

Director of the Irish branch of the European Nanomedicine Characterisation Laboratory (EU-NCL) for Advanced Materials preclinical testing since 2015

Review College member (elected), Fonds Wetenschappelijk Onderzoek - Vlaanderen (FWO), Belgium Since 2026

External academic lecturer and examiner in Advanced Nano- Bio- Technology, Translational Research, Innovation at Polytechnic of Turin, Italy Since 2026

Associated educator and examiner member of the NANOMED ERASMUS Mundus MSc educational master's degree doctorate, University of Pavia, Italy, Coordinated by University of Paris, France Since 2020

Chair of the Irish organising committee for the Nano World Cancer day since 2013

External academic lecturer and examiner in Nanomedicine, Biotechnology, Translational Research, Innovation at University of Tartu, Estonia Sicne 2020

External academic lecturer and examiner in Biomaterials, Biotechnology, Translational Research, Innovation at University of Cambridge, UK Since 2021

President of the Clinical Safety Advisory Board for Safe-N-Medtech project since 2023

Journals Reviewer for Cancer Research, Nature Nano, Nature Bioengineering, Nature Communications, Nature Methods and other for Springer-Nature publisher Since 2016

Review College member (elected), Fonds Wetenschappelijk Onderzoek - Vlaanderen (FWO), Belgium since 2026

External academic lecturer and examiner in Nanomedicine, Biotechnology, Translational Research, Innovation at University of Pavia, Italy Since 2016

Executive Board Member European Technology Platform (ETP) in Nanomedicine 2009 - 2018

Director of the Irish branch of the European Nanomedicine Characterisation Laboratory (EU-NCL) for Advanced Materials preclinical testing since 2015

External academic lecturer and examiner in Nanomedicine, Biotechnology, Translational Research, Innovation at University degli Studi di Milano-Bicocca, Italy since 2019

European Commission External Expert Evaluator (appointed) Since 2018

Expert Advisory Board Member of Metrino the flaghship EU Metrology for Innovative Nanotherapeutics project since 2024

Member of the Trinity St James's Cancer Institute Translational Nanomedicine Since 2019

Supervisory board member of the European Union EIT Health KIC 2022-2025

Expert evaluator panel member (elected) Fonds Wetenschappelijk Onderzoek - Vlaanderen (FWO), Belgium area Nanomedicine, Translational Research, Molecular Medicine, Clinical Research, Pharmaceutical technology, Biotechnology 2019-2025

European Commission External Expert Evaluator (appointed) since 2018

International Advisory Group EuroNanoForum 2013 - Area Nanomedicine, Healthcare, Nanobiotechnology and Biomaterials (before previous promotion) 2013

Associated educator and examiner member of the Erasmus Mundus Joint master's Degree Nanomedicine for Drug Delivery. (NANOMED EMJMD first phase), University of Anger, France 2016-2020

Guest Associate Editor in Nanobiotechnology and Nanomedicine - Frontiers in Bioengineering and Biotechnology, Nanobiotechnology Sep 2019

Editorial Board Member of Precision Nanomedicine June 2018

Editorial Board Member of Nature Scientific Reports - Nature Publishers Jan 2018

Academy of NanoGagliato, organising committee Dec-2016

Nano World Cancer day - organising committee Since 2013

Awards and Honours

Fellow of Trinity College Dublin (Elected) Apr 2021

My Green Lab Certification Accredited Professional Jul 2025

Trinity College Dublin Sustainability leadership award Mar 2025

European Association for Cancer Research (LBCAM lab) Feb 2024

Malvern Invited Talk at European NanoMedicine 2017 Apr 2017

FutureFlash! Best EC Project competition - EuroNanoForum 2015 Jul 2015

European Technology Platform on Nanomedicine 10th Anniversary Award (Local Organiser) Jun 2015

M.Sc. in Translational Oncology - Best new postgraduate course award as lecturer Apr 2014

EuroNanoForum 2013, Poster prize Jun 2013

Best Toxicology Paper 2012 - Society of Toxicology Mar 2012

International Academy of Nanomedicine, Second World Congress of Nanomedicine Oct 2010

Bioelectromagnetics Society and European Bioelectromagnetics Association award 2005

IEI/Medtronic Bioengineering Award Medal 2003

Calgary Award at the World Congress of Biomechanics, Calgary (Canada) 2002

Student award, 5th International Conference on Cellular Engineering, Aachen (Germany) 2001

Memberships

TTMI Executive Management Committee Member (TCD)(Appointed) 2025 – to date

Trinity Translational Medicine Institute (TTMI) Sustainability Committee Member (Appointed) 2025 – to date

Trinity College Green Laboratory and Sustainability Committee Member 2025 – to date

European Science Foundation (ESF) Expert member 2025 – to date

Scientific Advisory Panel member - Metrino Infrastructure EU Flagship project 2024 – to date

European Commission Health and Digital Executive Agency - External Expert member 2024 – to date

European Union Institute of Innovation and Technology (EIT) for Health, Supervisory Board members (elected) 2024 – to date

President of the Clinical Safety Advisory Board for Safe-N-Medtech OITB (elected) 2023 – to date

European Union Institute of Innovation and Technology (EIT) for Health, TCD Lead Principal Investigator 2022 – 2025

Associate Director for Research, School of Medicine (TCD) (elected) 2019 – 2024

European Member of the BioNanoNet, (Austria) (elected) 2018 – to date

Member of European Technology Platform (ETP) in Nanomedicine 2009 – to date

Chair of the Toxicology and Characterisation working group at the European Technology Platform in Nanomedicine (ETPN) (elected) 2012 – 2019

Vice-chairman of Nanodiagnostic Working Group - European Technology Platform in Nanomedicine (elected) 2009 – 2012

Member of the European Society of Molecular Imaging 2011 – 2015

Member of the Institution of Engineers of Ireland 1998 – 2008

Member of the European Society of Biomechanics 2004 – 2010

Member of the European Bioelectromagnetics Association 2004 – 2008

Membro dell'ordine degli Ingegneri Italiani 1998 – 2000

Member of the Bioelectromagnetics Society 2005 – 2006