Professor Lewis Winning
Professor/Consultant in Restorative Dent, Dental Science
Biography
Lewis Winning is Professor / Consultant in Restorative Dentistry, at the Dublin Dental University Hospital, Trinity College Dublin, Ireland. His main research focus is the impact of oral health on general health.
He completed his undergraduate dental training (BDS) at University of Dundee, Scotland, 2004. This was followed by specialty training firstly in Periodontology (DChDent) at Trinity College Dublin, Ireland, 2010. He then completed further specialty training in Restorative Dentistry, and also completed his research doctorate (PhD) at Queen's University Belfast, Northern Ireland 2018. Clinical fellowships include: FFD(Perio) RCSI 2010; FDS RCPSGlasg 2016; and FDS(Rest Dent) RCSEng 2018.
Current TCD research projects include the oral health aspects of the Irish Longitudinal Study of Aging (TILDA) study, and the Dublin Oral Health in PREVENT (OHiP) dementia study.
Publications and Further Research Outputs
Peer-Reviewed Publications
Kelly N, Blackwood B, Credland N, Stayt L, Causey C, Winning L, McAuley DF, Lundy FT, El Karim I., Oral health care in adult intensive care units: A national point prevalence study., Nursing in critical care, 2023
Winning L, Moran G, McClory M, El Karim I, Lundy FT, Patterson CC, Linden D, Cullen KM, Kee F, Linden GJ., Subgingival microbial diversity and respiratory decline: A cross-sectional study., Journal of Clinical Periodontology, 50, (7), 2023, p921 - 931
Ian Raynolds, Lewis Winning, Ioannis Polyzois, A three-year prospective cohort study evaluating implant stability utilising the Osstell® Mentor and Periotest® devices, Frontiers in Dental Medicine , 2023, p1 - 8
Vinay Sharma, Michael Crowe, Oscar Cassetti, Lewis Winning, Aifric O'Sullivan, Michael O'Sullivan, Dental caries in children in Ireland: A systematic review, Community Dentistry and Oral Epidemiology, 2023, p1 - 15
Sharma, Vinay and Cassetti, Oscar and Winning, Lewis and O'Sullivan, Michael and Crowe, Michael, Protocol for Developing a Dashboard for Interactive Cohort Analysis of Oral Health-Related Data, BMC Oral Health, 23, (1), 2023, p238
Kelly N, Gormley K, Linden DA, Winning L, McClory M, Lundy FT, Cullen KM, Linden GJ, El Karim IA., The association of denture wearing with reduced lung function and increased airflow limitation in 58-72 year old men. , PloS one, 18, (5), 2023, pe0285117
Winning L., Naseer A., De Looze C., Knight S.P., Kenny R.A., O'Connell B., Tooth loss and cognitive decline in community dwelling older Irish adults: A cross-sectional cohort study, Journal of Dentistry, 119, 2022
de Waal YCM, Winning L, Stavropoulos A, Polyzois I., Efficacy of chemical approaches for implant surface decontamination in conjunction with sub-marginal instrumentation, in the non-surgical treatment of peri-implantitis. A systematic review. , Journal of clinical periodontology, 2022
Winning L, De Looze C, Knight SP, Carey D, Meaney JF, Kenny RA, O'Connell B., Tooth loss and regional grey matter volume., Journal of dentistry, 129, 2022, p104393
Crowe, M., O' Sullivan, M., Winning, L., Cassetti, O., O' Connell, B., O' Sullivan, A., Gibney, E., Doyle, S.L., Bennett, A.E., Moynihan, P., Implementation of a food science and nutrition module in a dental undergraduate curriculum, European Journal of Dental Education, 2022
Mooney RE, Linden GJ, Winning L, Linden K, Kee F, McKeown PP, Woodside JV, Patterson CC, McKay GJ., Association of TGFB1 rs1800469 and BCMO1 rs6564851 with coronary heart disease and IL1B rs16944 with all-cause mortality in men from the Northern Ireland PRIME study., PloS one, 17, (8), 2022, pe0273333
Watson S., Woodside J.V., Winning L., Wright D.M., Srinivasan M., McKenna G., Associations between self-reported periodontal disease and nutrient intakes and nutrient-based dietary patterns in the UK Biobank, Journal of Clinical Periodontology, 2022
Winning L, El Karim IA, Linden GJ, Irwin CR, Killough SA, Lundy FT., Differential regulation of NPY and SP receptor expression in STRO-1+ve PDLSCs by inflammatory cytokines., Journal of periodontal research, 57, (1), 2022, p186-194
Chapter 1. Management of Chronic Dental Disease. in, editor(s)McKenna, G., Allen, F. & Burke, F. , Clinical Cases in Gerontology. , Wiley-Blackwell, 2021, pp13 - 24, [Winning, L., & Irwin, C. ]
Reynolds, I., Naughton, D., Winning, L., & Harrison, P., Application of the new periodontal classification: generalised periodontitis., Journal of the Irish Dental Assoication, 67, 2021, p(1-6 Periodontics)
Birt, Rachel, Healy, Claire M, MacCarthy, Denise, Winning, Lewis, A Review of the Evidence for the Provision of the Routine Scale and Polish for the Prevention of Periodontal Disease, Dental Update, 48, (3), 2021, p201-205
Nolan, M., Aljudaibi, S. A., Harrison, P., & Winning, L., Application of the new periodontal classification: Part 2., Journal of the Irish Dental Association, 67, 2021, p(1-6 Periodontics)
Winning, Lewis, Lundy, Fionnuala T., Blackwood, Bronagh, McAuley, Daniel F., El Karim, Ikhlas, Oral health care for the critically ill: a narrative review, Critical Care, 25, (1), 2021
Andreas Stavropoulos, Kristina Bertl, Lewis Winning, Ioannis Polyzois, What is the influence of implant surface characteristics and/or implant material on the incidence and progression of peri-implantitis? A systematic literature review. , Clinical Oral Implants Research., 32, (Suppl 21), 2021, p203 - 229
Winning L., Patterson C.C., Linden K., Cullen K.M., Kee F., Linden G.J., Systemic inflammation and the relationship between periodontitis, edentulism, and all-cause mortality: A 17-year prospective cohort study, Journal of Clinical Periodontology, 48, (9), 2021, p1260 - 1269, p1260-1269
Roberts, A., Winning, L., & Harrison, P. , Periodontitis: all change please? Introduction to the new S3-level treatment guidelines., Journal of the Irish Dental Association, 67, (5), 2021, p262 - 266
Relationship Between Periodontal Disease and Nutrition in, Springer International Publishing, 2021, pp53-61 , [Winning, Lewis, Moore, Ciarán]
Kelly, Niamh, Winning, Lewis, Irwin, Christopher, Lundy, Fionnuala T., Linden, Dermot, McGarvey, Lorcan, Linden, Gerard J., El Karim, Ikhlas A., Periodontal status and chronic obstructive pulmonary disease (COPD) exacerbations: a systematic review, BMC Oral Health, 21, (1), 2021
Periodontitis and respiratory diseases in, editor(s)Hirschfeld, Josefine / Chapple, lain L. C. , Periodontitis and Systemic Diseases: Clinical Evidence and Biological Plausibility, United Kingdom, QUINTESSENCE PUBLISHING, 2021, [Lewis Winning & Gerard Linden]
Winning L, Patterson CC, Linden K, Evans A, Yarnel J, McKeown PP, Kee F, Linden GJ., Periodontitis and risk of prevalent and incident coronary heart disease events., Journal of clinical periodontology, 2020
Winning L, Polyzois I, Berglund JS, Renvert S., Periodontitis and air flow limitation in older Swedish individuals., Journal of Clinical Periodontology, 47, (6), 2020, p715 - 725
Wright DM, McKenna G, Nugent A, Winning L, Linden GJ, Woodside JV., Association between diet and periodontitis: a cross-sectional study of 10,000 NHANES participants., The American journal of clinical nutrition, 2020
Winning L., Patterson C., Blankenberg S., Zeller T., Kee F., Linden G., Contribution of 30 Systemic Biomarkers to 10-Year Periodontal Status, J Dent Res, 2019 IADR/AADR/CADR General, Vancouver, BC, Canada, 21/06/2019, 98, (A), 2019
Linden G.,Winning L., McKeown P., Linden K., Patterson C., Kee F., Periodontitis And Incident Coronary Events In Middle-Aged Men , J Dent Res, 2019 IADR/AADR/CADR General, Vancouver, BC, Canada, 19/06/2019, 98, (A), 2019
Winning L, El Karim IA, Lundy FT, A Comparative Analysis of the Osteogenic Potential of Dental Mesenchymal Stem Cells. , Stem cells and development, 2019
Lewis Winning, Chris C. Patterson, Kathy M. Cullen, Frank Kee, Gerard J. Linden, Chronic periodontitis and reduced respiratory function, Journal of Clinical Periodontology, 2019
Lewis Winning, The Osteogenic potential of periodontal ligament stem cells, Queen's University Belfast, 2018
Winning L., El Karim I., Linden G., Irwin C., Lundy F., A Comparative Analysis of the Osteogenic Differentiation Potential of Intra-subject Dental Mesenchymal Stem Cells, J Dent Res, 2018 IADR/PER General Session, London, England, 28/07/2018, 97, (B), 2018
Linden G.,Winning L., McGuiness B., McEvoy C., Kee F., Association Between Periodontitis and Cognitive Function in Middle-aged Men , J Dent Res, 2018 IADR/PER General Session, London, England, 25/07/2018, 97, (B), 2018
Lewis Winning, Gerard J Linden, Division of Restorative Dentistry & Periodontology, Dublin Dental University Hospital, Trinity College Dublin, Ireland, Centre for Public Health, School of Medicine Dentistry and Biomedical Sciences, Queen#x2019;s University Belfast, Belfast, Northern Ireland, A Review of the Relationship Between Chronic Periodontitis and Diabetes, US Endocrinology, 14, (2), 2018, p80
L. Winning, L. Robinson, A. R. Boyd, I. A. El Karim, F. T. Lundy, B. J. Meenan, Osteoblastic differentiation of periodontal ligament stem cells on non-stoichiometric calcium phosphate and titanium surfaces, Journal of Biomedical Materials Research Part A, 2017
Winning L., Patterson C., Lundy F., Cullen K., Kee F., Linden G., Subgingival Porphyromonas gingivalis Associates With Decreased Lung Function , J Dent Res, 2017 IADR/AADR/CADR General Session, San Francisco, California, 23/03/2017, 96, (A), 2017
Lewis Winning, Christopher C. Patterson, Charlotte E. Neville, Frank Kee, Gerard J. Linden, Periodontitis and incident type 2 diabetes: a prospective cohort study, Journal of Clinical Periodontology, 44, (3), 2017, p266--274
Winning L., Patterson C., Cullen K., Kee F., Linden G., Chronic periodontitis and decreased respiratory function: a prospective cross-sectional study. , J Dent Res, 2017 British Division IADR Meeting, Plymouth, United Kingdom , 08/09/2017, 96, (B), 2017
N.T. Hashim, G.J. Linden, L. Winning, M.E. Ibrahim, B.G. Gismalla, F.T. Lundy, I.A. El Karim, Putative periodontal pathogens in the subgingival plaque of Sudanese subjects with aggressive periodontitis, Archives of Oral Biology, 2017
Lewis Winning, Amanda Willis, Brian Mullally, Christopher Irwin, Desquamative gingivitis " aetiology, diagnosis and management, Dental Update, 44, (6), 2017, p564--570
Keshtkar F, Ford C, Rice M, Gray R, Loughrey M, Bankhead P, Cardwell C, McQuaid S, O"Neill R, Arthur K, Bingham V, McGready C, Gavin A, James J, Winning L, Annual Trainee Doctors" Prize Day, Thursday 10th November 2016 : Postgraduate Centre, Belfast City Hospital, The Ulster medical journal, 2017
Linden G., McEvoy C., Winning L., Kee F., Woodside J., Association between number of teeth and healthier food choices in older men , J Dent Res, 2017 British Division IADR Meeting, Plymouth, United Kingdom , 08/09/2017, 96, (B), 2017
Lewis Winning, Gerard J. Linden, Periodontitis and Systemic Disease: Association or Causality?, Current Oral Health Reports, 2017
Winning, L., El Karim, I., Linden, G., Killough, S., Irwin, C., & Lundy, F., Neuropeptide Y Enhances the Osteogenic Potential of Periodontal Ligament Stem Cells, IADR/APR General Session, Seoul, Korea, 06/25/2016, 95, ((Spec Iss B)), 2016
Moore, C., Killough, S., Markey, N., Winning, L., McKenna, G., Oral Health Status of Patients Undergoing Treatment for Head and Neck Oncology in Northern Ireland, The European journal of prosthodontics and restorative dentistry, 24, (2), 2016, p58-62
Introduction to periodontal disease in, editor(s)Stephen Creanor , Clinical Oral Biology, UK, Wiley Blackwell, 2016, pp152 - 161, [Linden G., Winning L.]
Winning, L., El Karim, I., Linden, G., Killough, S., Irwin, C., & Lundy, F., Neuropeptide Y Enhances the Osteogenic Potential of Periodontal Ligament Stem Cells, IADR/APR General Session, Seoul, Korea, 06/25/2016, 95, ((Spec Iss B)), 2016
Winning, L., Patterson, C.C., Cullen, K.M., Stevenson, K.A., Lundy, F.T., Kee, F., Linden, G.J., The association between subgingival periodontal pathogens and systemic inflammation, Journal of Clinical Periodontology, 42, (9), 2015, p799-806
Winning, L., Rutledge L., McLister R., Meenan B., Boyd A., El-Karim I., Lundy F., Periodontal ligament stem cell osteoblastic response to nanostructured titanium surfaces., Journal of dental research, IADR Irish Division, Dublin, 94, (Spec Iss B.), 2015
Hon, J., Johnson-Idan, J., Linden, G., Winning, L., Sabbah, W., & Hughes, F., The association of calcium channel blockers with periodontal disease., BSODR, Cardiff, United Kingdom, 09/14/2015, 94, ((Spec Iss B)), 2015
Winning, L., Rutledge L., McLister R., Meenan B., Boyd A., El-Karim I., Lundy F., Periodontal ligament stem cell osteoblastic gene expression response to nanostructured titanium surfaces., UK Society for Biomaterials., Belfast, UK., 2015
Winning, L., El Karim, I., Killough, S., Linden, G., Irwin, C., & Lundy, F., The Substance P Receptor (Tachykinin Receptor 1), is Expressed on Stro-1 +ve Periodontal Ligament Stem Cells, J Dent Res, IADR/AADR/CADR General Session, Boston, Massachusetts, 03/14/2015, 94, ((Spec Iss A)), 2015
Lewis Winning, Gerard J. Linden, Periodontitis and systemic disease, BDJ Team, 2, (10), 2015, p15163
Winning, L., Patterson, C., Lundy, F., Kee, F., Young, I., & Linden, G., The association between periodontal pathogens and measures of adiposity., J Dent Res, BSODR, Cardiff, 09/16/2015, 94, (B), 2015, pp117
Linden, G., Winning, L., Lundy, F., Kee, F., & Patterson, C., Abdominal adiposity and periodontitis: A Mendelian randomisation study., J Dent Res, BSODR, Cardiff, United Kingdom, 09/16/2015, 94, (B), 2015, pp117
Winning, L., Patterson, C., McClean, K., Kee, F., & Linden, G., Subgingival Porphyromonas gingivalis associates with raised C-reactive protein levels., J Dent Res, Pan European Region / IADR Meeting, Dubrovnik, Croatia., 09/12/2014, (93), C, 2014, pp320
Winning L, Polyzois I, Nylund K, Kelly A, Claffey N, A placebo-controlled trial to evaluate an anesthetic gel when probing in patients with advanced periodontitis., Journal of Periodontology, 83, (12), 2012, p1492-8
Lewis Andrew Winning, A split mouth, double blind, placebo controlled trial to assess the impact of a lidocaine/prilocaine 2.5%/2.5 % anaesthetic gel when carrying out probing in a group of advanced periodontitis patients, Trinity College Dublin, The University of Dublin, 2010
Campbell A.M., McMullan R.E., Winning, L., Baxter K., Collins J., Lung Z., Retention regimes following fixed appliance therapy"a change of practice re-audited., Br Orthod Soc Clin Effectiveness Bull., (23), 2009, pp20 - 22
Research Expertise
Description
Oral health is important. The mouth has been described as a "window" to the rest of the body. There is increasing evidence of the association between oral disease and chronic conditions including diabetes, heart disease, respiratory disease, and cognitive decline. The World Health Organization's (WHO) Global Oral Health Action Plan 2023-2030 specifically highlights the importance of the integration of Oral Health and General Health, also highlighting the need for a multi-disciplinary approach to research in this area. The overall aim of my research is to investigate the relationship between oral health and general health, and explore the underlying mechanisms involved.Recognition
Representations
External Examiner for Queen Mary University of London (QMUL)
Faculty of Heath Sciences, Research Ethics Committee
Honorary Secretary, Irish Division IADR
Honorary Treasurer, Irish Society of Periodontology
Awards and Honours
TCD Provost's PhD Project Awards
QUB Researcher Plus / Future Ready Award
Northern Ireland Medical and Dental Training Agency - Excellence in Research Award
John Zamet Memorial Prize in Periodontal Research
IADR Irish Division - Senior Hatton Award
British Society of Periodontology Research Award
Irish Society of Periodontology Noel Claffey Research Award