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Dr. Sean Kennelly
Clinical Associate Professor, Medical Gerontology
Clinical Associate Professor, Trinity Inst. of Neurosciences (TCIN)

Biography

Professor Sean Kennelly MB BCh BAO PhD FRCP(Lond) FRCPI is a consultant physician in geriatric and stroke medicine in Tallaght University Hospital (TUH) and Clinical Associate Professor of Medical Gerontology in Trinity College. He is Director of the Institute for Memory and Cognition, and the Cognitive Clinical Trials Unit in Tallaght University Hospital, Dublin. He is clinical director of the National Intellectual Disability Memory Service in TUH. He is co-lead investigator on HRB-funded Dementia Trials Ireland, a national clinical trials network, and is principle investigator on HRB-funded of Dementia Research Network Ireland (DRNI). A fellow of the Royal College of Physicians in London & Ireland, he has extensively published in his main research areas of Ageing, brain health, dementia, and Inflammaging. He has served as chief and principal investigator on several international clinical trials in early-stage Alzheimer's disease. He is principle investigator and lead-clinical advisor on several industry collaborations investigating novel applications of digital gait and speech biomarkers in detection of cognitive decline. He is a member of the clinical and research advisory panel for the Alzheimer's Society Ireland and a principal investigator in the Trinity College Institute of Neuroscience. He is a faculty member for the Global Brain Health Institute in Trinity College Dublin. He is a member of the clinical and research advisory panel for the Alzheimer's Society of Ireland. He is on several clinical and service advisory committees for the national clinical program for older people and the national dementia office. He is a member of the national dementia strategy monitoring group within the department of health. He served as associate dean of higher specialty training in general internal medicine in the Royal College of Physicians of Ireland 2017-2021.

Publications and Further Research Outputs

Peer-Reviewed Publications

Helena Dolphin, Adam H Dyer, Laura Morrison, Susan D Shenkin, Tomas Welsh, Sean P Kennelly, New horizons in the diagnosis and management of Alzheimer"s Disease in older adults, Age and Ageing, 53, (2), 2024 Journal Article, 2024 DOI

Hu Z, Ondrejcak T, Yu P, Zhang Y, Yang Y, Klyubin I, Rowan MJ, Kennelly SP, Hu NW, Do tau-synaptic long-term depression interactions in the hippocampus play a pivotal role in the progression of Alzheimer's disease?, Neural Regeneration Research, 18, (6), 2023, p1213-1219 Journal Article, 2023 DOI

Murphy C, Dyer AH, Lawlor B, Kennelly SP, for the NILVAD study group, What is the impact of ongoing statin use on cognitive decline and dementia progression in older adults with mild-moderate Alzheimer disease?, PLoS ONE, 2023 Journal Article, 2023 DOI

Donnell DO, Romero-Ortuno R, Kennelly SP, O'Neill D, Donoghue PO, Lavan A, Cunningham C, McElwaine P, Kenny RA, Briggs R., The 'Bermuda Triangle' of orthostatic hypotension, cognitive impairment and reduced mobility: prospective associations with falls and fractures in The Irish Longitudinal Study on Ageing. , Age and Ageing, 52, (2), 2023, pafad005 Journal Article, 2023 DOI URL

McGlinchey, E., Daly, L., Allen, A., Dennehy, H., Buttery, N., Corr, C., McCallion, P., Kennelly, S., Dunne, P., McCarron, M., Developing Best Practice Guidelines for Post-Diagnostic Dementia Support for People with an Intellectual Disability, 33rd Alzheimer Europe Conference, Helsinki, 16-18 October 2023, 2023 Oral Presentation, 2023

Grey T, Xidous D, O'Donoghue J, Kennelly S, O'Neill D, Improving Quality of Life and Enhancing COVID-19 Infection Control in Existing Residential Care Settings for Older People: Universal Design Guidelines, Dublin, Centre for Excellence in Universal Design, 2022, p1 - 44 Report, 2022 URL

Grey T, Xidous D, O'Donoghue J, Kennelly S, O'Neill D, Universal Design for Improving Quality of Life and Enhancing COVID-19 Infection Control in Existing Residential Care Settings for Older People: Research Report, Dublin, Centre for Excellence in Universal Design, 2022, p1 - 110 Report, 2022 URL

Dyer AH, Noonan C, McElheron M, Batten I, Reddy C, Connolly E, Pierpoint R, Murray C, Leonard A, Higgins C, Reilly P, Boran G, Phelan T, McCormack W, O'Neill D, Fallon A, Brady G, O'Farrelly C, Bourke NM, Kennelly SP., Previous SARS-CoV-2 Infection, Age, and Frailty Are Associated With 6-Month Vaccine-Induced Anti-Spike Antibody Titer in Nursing Home Residents, Journal of the American Medical Directors Association, 2022 Journal Article, 2022 DOI URL

Dennehy H., Allen A.P., McGlinchey E., Buttery N., Garcia-Dominguez L., Chansler R., Corr C., Dunne P., Kennelly S., Daly L. McCallion P. and McCarron M., A scoping review of post-diagnostic dementia supports for people with intellectual disability, Aging and Mental Health, 2022 Journal Article, 2022 URL

Xidous D, Grey T, Kennelly S, O'Neill D, Understanding the knowledge and engagement of facilities management with dementia- friendly design in Irish hospitals: an exploratory study, Facilities, 9, 2021, p601 - 614 Journal Article, 2021 DOI URL

Waldron, C., Cahill, J., Cromie, S., Delaney, T., Kennelly, S., Pevnick, J., and Grimes, T., Personal Electronic Records of Medications (PERMs) for medication reconciliation at care transitions: a rapid realist review., BMC Medical Informatics and Decision Making, 21, (307), 2021, p1 - 17 Journal Article, 2021 DOI TARA - Full Text

Doyle P, Ryan DJ, Kennelly S, O'Neill D, Frequency and intensity of medical interventions in a nursing home during COVID-19 Pandemic, Ir Med J, 114, (3), 2021, pP301 Journal Article, 2021 URL

O'Neill D, Kennelly S, Responding to responsive behaviour in Alzheimer's disease, Lancet, 398, (10303), 2021, p842 Journal Article, 2021 URL DOI

Kennelly SP, Dyer AH, Noonan C, Kennelly SM, Martin A, O'Neill D, Fallon A, Asymptomatic carriage rates and case-fatality of SARS-CoV-2 infection in residents and staff in Irish nursing homes, Age and Ageing, 50, (1), 2021, p49 - 54 Journal Article, 2021 URL DOI

Peeters G, Bennett M, Donoghue OA, Kennelly S, Kenny RA., Understanding the aetiology of fear of falling from the perspective of a fear-avoidance model - A narrative review., Clinical psychology review, 79, 2020, p101862 Journal Article, 2020 DOI

Dyer AH, Murphy C, Lawlor B, Kennelly SP, NILVAD Study Group"", Long-term proton-pump inhibitor use in older adults with mild-to-moderate Alzheimer's disease: Are there cognitive consequences?, European journal of internal medicine, 2020 Journal Article, 2020

Doyle P, Kennelly S, Ryan D, O'Neill D, Frequency and intensity of medical interventions in a nursing home during COVID-19 Pandemic, European Geriatric Medicine, 16th International E-Congress of the European Geriatric Medicine Society, Virtual, 7-9 Oct, 11, (Suppl 1), 2020, ppS49 Published Abstract, 2020 URL DOI

Dyer AH, Lawlor B, Kennelly SP, NILVAD Study Group., Gait speed, cognition and falls in people living with mild-to-moderate Alzheimer disease: data from NILVAD., BMC geriatrics, 20, (1), 2020, p117 Journal Article, 2020 DOI

Dyer AH, Murphy C, Lawlor B, Kennelly SP, NILVAD Study Group., Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD., Journal of the American Medical Directors Association, 21, (2), 2020, p194-200 Journal Article, 2020 DOI

Bracken-Scally M, Timmons S, O'Shea E, Gallagher P, Kennelly SP, Hamilton V, O'Neill D., Second Irish National Audit of Dementia Care in Acute Hospitals, Offaly, National Dementia Office, 2020, p1 - 228 Report, 2020 Other URL

Floyd R, Dyer AH, Kennelly SP, Non-pharmacological interventions for cognitive impairment in women with breast cancer post-chemotherapy: A systematic review., Journal of geriatric oncology, 2020 Journal Article, 2020

Murphy C, Dyer AH, Lawlor B, Kennelly SP, NILVAD Study Group, Potentially inappropriate medication use in older adults with mild-moderate Alzheimer's disease: prevalence and associations with adverse events., Age and ageing, 2020 Journal Article, 2020 DOI TARA - Full Text

Fallon A, Dyer A, Martin R, Kennelly S, Martin R, O'Neill D, Kennelly S, Profiling COVID-19 infection in Irish nursing homes, European Geriatric Medicine, 16th International E-Congress of the European Geriatric Medicine Society, Virtual, 7-9 Oct, 11, (Suppl 1), 2020, ppS51 Published Abstract, 2020 DOI URL

Fallon A, Dukelow T, Kennelly S, O'Neill D, COVID-19 in Nursing Homes, QJM, 113, (6), 2020, p391 - 392 Journal Article, 2020 URL DOI

Abdullah L, Crawford F, Tsolaki M, Börjesson-Hanson A, Olde Rikkert M, Pasquier F, Wallin A, Kennelly S, Ait-Ghezala G, Paris D, Hendrix S, Mullan M, The Influence of Baseline Alzheimer's Disease Severity on Cognitive Decline and CSF Biomarkers in the NILVAD Trial., Frontiers in neurology, 2020 Journal Article, 2020

Dyer AH, Lawlor B, Kennelly SP, NILVAD Study Group, Sexual dimorphism in the association of APOE "4 genotype with cognitive decline and dementia progression in mild-to-moderate Alzheimer disease., International journal of geriatric psychiatry, 2020 Journal Article, 2020

Dyer A, McKenna L, Gamage G, Bourke N, Killane I, Widdowson M, Woods C, Gibney J, Reilly R, O'Neill D, Kennelly S. , Cognitive performance in midlife type 2 diabetes: results from the ENBIND study, Diabetic Medicine, 2020 Journal Article, 2020 URL DOI

Dyer AH, Murphy C, Lawlor B, Kennelly SP, Study Group For The Nilvad, Social networks in mild-to-moderate Alzheimer disease: longitudinal relationships with dementia severity, cognitive function, and adverse events. , Aging & mental health, 2020 Journal Article, 2020

Dyer AH, Murphy C, Lawlor B, Kennelly SP, NILVAD StudyGroup, Sedative Load in Community-Dwelling Older Adults with Mild-Moderate Alzheimer's Disease: Longitudinal Relationships with Adverse Events, Delirium and Falls., Drugs & aging, 2020 Journal Article, 2020 DOI

Anderson DC, Grey T, Kennelly S, O'Neill D, Nursing Home Design and COVID-19: Balancing Infection Control, Quality of Life, and Resilience, Journal of the American Medical Directors Association, 21, (11), 2020, p1519 - 1524 Journal Article, 2020 URL DOI

Dyer AH, McKenna L, Batten I, Jones K, Widdowson M, Dunne J, Conlon N, Reilly R, Woods CP, O'Neill D, Gibney J, Bourke NM, Kennelly SP., Peripheral Inflammation and Cognitive Performance in Middle-Aged Adults With and Without Type 2 Diabetes: Results From the ENBIND Study, Front. Aging Neurosci, 12, 2020 Journal Article, 2020 DOI URL

Meagher D, Adamis D, Timmons S, O'Regan NA, O'Keeffe S, Kennelly S, Corby C, Meaney AM, Reynolds P, Mohamad M, Glynn K, O'Sullivan R, Developing a guidance resource for managing delirium in patients with COVID-19., Irish journal of psychological medicine, 2020 Journal Article, 2020

Xidous D, Grey T, Kennelly SP, O'Neill D, Dementia Friendly Hospital Design: Key Issues for Patients and Accompanying Persons in an Irish Acute Care Public Hospital , Health Environments Research & Design, 13, (1), 2020, p48 - 67 Journal Article, 2020 DOI URL

Martin A, Boyle N, Cooke J, Kennelly SP, Martin R, Mulroy M, O'Connor M, O'Keeffe S, O'Neill D on behalf of the Irish Society of Physicians in Geriatric Medicine, Responding to Needs of Residents in Long Term Care in Ireland, Ir Med J, 113, (9), 2020, pP181 Journal Article, 2020 URL

Dyer AH, Murphy C, Briggs R, Lawlor B, Kennelly SP, NILVAD Study Group, Antidepressant use and orthostatic hypotension in older adults living with mild-to-moderate Alzheimer disease., International journal of geriatric psychiatry, 2020 Journal Article, 2020

Dyer AH, Briggs R, Mockler D, Gibney J, Kennelly SP, Non-Pharmacological Interventions for Cognition in Patients with Type 2 Diabetes Mellitus: A Systematic Review., Quarterly Journal Medicine, 2019 Journal Article, 2019 DOI

Dyer AH, Murphy C, Segurado R, Lawlor B, Kennelly SP, NILVAD Study Group, Is Ongoing Anticholinergic Burden Associated With Greater Cognitive Decline and Dementia Severity in Mild to Moderate Alzheimer's Disease?, The journals of gerontology. Series A, Biological sciences and medical sciences, 2019 Journal Article, 2019

Dyer A, Batten I, Killane I, Woods C, Gibney J, O'Neill D, Reilly R, Bourke N, Kennelly S , Linking Diabetes and Dementia Risk: A Role for Aβ-42 Induced Activation of the NLRP3 Inflammasome? Results from the ENBIND Study , Age and Ageing, Irish Gerontoloppgical Society 67th Annual Scientific Meeting, Cork, 27-28 Sept 2019, 48, (Suppl 3), 2019, ppiii26 Meeting Abstract, 2019 DOI

Cognition and Health Aging in, editor(s)Coll, PP , Healthy Aging: A Complete Guide to Clinical Management,, New York, Springer-Verlag New York, 2019, pp169 - 180, [Briggs R, Kennelly S, O'Neill D] Book Chapter, 2019 DOI URL

Tobin F, McGuinn C, Pearson C, Dooky J, McHale C, Coughlan T, O'Neill D, Ryan D, Collins R, Kennelly S, Does a Pen and Paper Assessment of Executive Skills Correlate with Functional Decline Identified Through Specialised Occupational Therapy Assessment?, Age and Ageing, Irish Gerontoloppgical Society 67th Annual Scientific Meeting, Cork, 27-28 Sept 2019, 48, (Suppl 3), 2019, ppiii54 Meeting Abstract, 2019 DOI

Briggs R, Carey D, Claffey P, McNicholas T, Donoghue O, Kennelly SP, Kenny RA, Do Differences in Spatiotemporal Gait Parameters Predict the Risk of Developing Depression in Later Life?, J Am Geriatr Soc, 2019 Journal Article, 2019 DOI URL

McHale C, Sharkey J, Coughlan T, O'Neill D, Dookhy J, Sheridan L, Kennelly S, Hearing Loss as a Potentially Modifiable Risk Factor in People with Mild Cognitive Symptoms Attending a Specialist Memory Service, Age and Ageing, Irish Gerontoloppgical Society 67th Annual Scientific Meeting, Cork, 27-28 Sept 2019, 48, (Suppl 3), 2019, ppiii55 Meeting Abstract, 2019 DOI

Dyer A, Killane I, Bourke N, Woods C, Gibney J, O'Neill D, Reilly R, Kennelly S, Does Dual-Task Gait Speed Predict Cognitive Performance in Midlife Type 2 Diabetes? Baseline Results from the ENBIND Study, Age and Ageing, Irish Gerontoloppgical Society 67th Annual Scientific Meeting, Cork, 27-28 Sept 2019, 48, (Suppl 3), 2019, ppiii3-4 Meeting Abstract, 2019 DOI

Gilligan, T.M. and Sibilia, F. and Farrell, D. and Lyons, D. and Kennelly, S.P. and Bokde, A.L.W., No relationship between fornix and cingulum degradation and within-network decreases in functional connectivity in prodromal Alzheimer†s disease, PLoS ONE, 14, (10), 2019 Journal Article, 2019 DOI TARA - Full Text

Briggs R, Drumm B, Dwyer R, O'Neill D, Kennelly SP, Coughlan T, Collins R, Awareness of atrial fibrillation-effectiveness of a pilot national awareness campaign, Ir J Med Sci, 2019 Journal Article, 2019 DOI URL

Harkins P, O'Brien H, McCartan D, Nasir N, Twomey B, Srikumar K, Coughlan T, Kennelly S, McElwaine P, O'Neill D, Ryan D, Ronan C, A Hospital Wide Point Prevalence of Adult Urinary Incontinence and Audit of Continence Care., Age and Ageing, 2019 Journal Article, 2019 DOI URL

Sheridan L, McHale C, Dookhy J, Coughlan T, O'Neill D, Collins R, Ryan D, Kennelly S , Incorporating Neurolinguistics and the Role of Speech and Language Therapy in a Specialist Memory Service , Age and Ageing, Irish Gerontoloppgical Society 67th Annual Scientific Meeting, Cork, 27-28 Sept 2019, 48, (Suppl 3), 2019, ppiii49 Meeting Abstract, 2019 DOI

Peeters G., Feeney J., Carey D., Kennelly S., Kenny R.A., Fear of falling: A manifestation of executive dysfunction?, International Journal of Geriatric Psychiatry, 2019 Journal Article, 2019 DOI

Harkins P, O'Brien H, McCartan D, Nasir N, Twomey B, Srikumar K, Coughlan T, Kennelly S, McElwaine P, O'Neill D, Ryan D, Ronan C, Corrigendum: A Hospital Wide Point Prevalence of Adult Urinary Incontinence and Audit of Continence Care., Age and ageing, 2019 Journal Article, 2019

Dookhy J, McHale C, Kennelly S, Coughlan T, Collins R, Ryan D, O'Neill D, Cardiovascular Risk Profile in People with Mild Cognitive Symptoms Attending a Memory Service - an Opportunity to Promote Brain Health , Age and Ageing, Irish Gerontoloppgical Society 67th Annual Scientific Meeting, Cork, 27-28 Sept 2019, 48, (Suppl 3), 2019, ppiii32-33 Meeting Abstract, 2019 DOI

McHale C, McGovern M, Dewergifosse J, Domsa M, McMahon A, Timmons F, Greene J, Tobin F, Bennett A, Donnelly M, Coughlan T, O'Neill D, Dookhy J, Hyland C, Scanlan J, Ryan D, McElwaine P, Kennelly S, Insights into Dementia- An Integrated Care Approach to Family Support, Age and Ageing, Irish Gerontoloppgical Society 67th Annual Scientific Meeting, Cork, 27-28 Sept 2019, 48, (Suppl 3), 2019, ppiii62 Meeting Abstract, 2019 DOI

Briggs R, McHale C, Fitzhenry D, O'Neill D, Kennelly S, Dementia, disclosing the diagnosis, QJM, 2018 Journal Article, 2018 URL DOI

Mieke Deschodt, Benoit Boland, Cecilia M. Lund, Kai Saks, Venetia-Sofia Velonaki, Olafur Samuelsson, Sean Kennelly, Mark Anthony Vassallo, Gregor Veninšek, Johan Flamaing, Implementation of geriatric care models in Europe (imAGE.eu): a cross-sectional survey in eight countries, European Geriatric Medicine, 9, (6), 2018, p771--782 Journal Article, 2018

Briggs R, Carey D, O'Halloran A, Kenny RA, Kennelly SP, Validation of the 8-item Centre for Epidemiological Studies Depression Scale in a cohort of community-dwelling older people: data from The Irish Longitudinal Study on Ageing (TILDA) , European Geriatric Medicine, 9, (1), 2018, p121-126 Journal Article, 2018 DOI URL

Briggs R, Carey D, Kenny RA, Kennelly SP, What is the Longitudinal Relationship between Gait Abnormalities and Depression in a Cohort of Community-Dwelling Older People? Data From the Irish Longitudinal Study on Ageing (TILDA) , Am J Geriatr Psychiatry, 26 , (1), 2018, p75-86 Journal Article, 2018 DOI

Lawlor B.A., Segurado, R., Kennelly, S., Olde Rikkert, M.G., Howard, R., Pasquier, F., Börjesson-Hanson, A., Tsolaki, M., Lucca, U., D. Molloy, W., Coen, R.F., Riepe, M.W., Kálmán, J., Kenny R.A., Cregg, F., O'Dwyer, S., Walsh C., Adams, J., Banzi, R., Breuilh, L., Daly, L., Hendrix, S., Aisen, P., Gaynor, S., Sheikhi, A., Taekema, D.G., Verhey, F.R., Nemni, R., Nobili, F., Francheschi, M., Frisoni, G., Zanetti, O., Konsta, A., Anastasios, O., Nenopoulou, S., Tsolaki-Tagaraki, F., Pakaski, M., Dereeper, O., de la Sayette, V., Senechal, O., Lavenu, I., Godefroy, O., Calais, G., Crawford, F., Mullan, M., for the NILVAD Study Group. , Nilvadipine in mild to moderate Alzheimer's disease: a randomised controlled trial. , PLOS Medicine , 15, (9), 2018, p1 - 20 Journal Article, 2018 TARA - Full Text

Dyer AH, Foley T, O'Shea B, Kennelly SP, Dementia Diagnosis and Referral in General Practice: A Representative Survey of Irish General Practitioners, 2018 Journal Article, 2018 URL

Dyer AH, Foley T, O'Shea B, Kennelly SP. , Cognitive assessment of older adults in general practice: the collateral history , Ir J Med Sci. , 2018 Journal Article, 2018 URL DOI

Briggs R, Kennelly SP, Kenny RA. , Does baseline depression increase the risk of unexplained and accidental falls in a cohort of community-dwelling older people? Data from The Irish Longitudinal Study on Ageing (TILDA). , Int J Geriatr Psychiatry., 33, (2), 2018, pe205-e211 Journal Article, 2018 DOI

, DEMENTIA FRIENDLY HOSPITALS FROM A UNIVERSAL DESIGN APPROACH: RESEARCH AND GUIDELINES, Innovation in Aging, 2018 Journal Article, 2018

Smyth H, Kennelly SP, O'Neill D, Modern Approaches To Self-Neglect, Ir Med J, 111, (5), 2018, pP748 Journal Article, 2018 URL

Peeters G, Leahy S, Kennelly SP, Kenny RA. , Is fear of falling associated with decline in global cognitive functioning in older adults: findings from the The Irish Longitudinal Study on Ageing (TILDA) , J Am Med Dir Assoc., 2018 Journal Article, 2018 URL URL

D'Alton M, Coughlan T, Cogan N, Greene S, McCabe DJH, McCarthy A, Murphy S, Walsh R, O'Neill D, Kennelly S, Ryan D, Collins R, Patterns of Mortality in Modern Stroke Care, Ir Med J, 111, (5), 2018, pP750 Journal Article, 2018 URL

Briggs R, Carey D, Kennelly SP, Kenny RA, Longitudinal Association Between Orthostatic Hypotension at 30 Seconds Post-Standing and Late-Life Depression., Hypertension, 2018, p816- Journal Article, 2018 URL TARA - Full Text DOI

Abdullah L, Crawford F, Langlois H, Tsolaki M, Börjesson-Hanson A, Olde Rikkert M, Pasquier F, Wallin A, Kennelly S, Hendrix S, Blennow K, Lawlor B, Mullan M, Exploratory analyses suggest less cognitive decline with nilvadipine treatment in very mild Alzheimer"s disease subjects, 2018 Journal Article, 2018

Fallon A, Kilbane L, Briggs R, Dyer A, Nabeel S, McElwaine P, Collins DR, Coughlan T, O'Neill D, RyanD, Kennelly SP, Screening for frailty in older emergency department patients: The utility of the Survey of Health, Ageing and Retirement in Europe Frailty Instrument (SHARE-FI) , QJM, 2018 Journal Article, 2018 URL DOI

Briggs R, Carey D, Claffey P, McNicholas T, Newman L, Nolan H, Kennelly SP, Kenny RA, The association between frontal lobe perfusion and depressive symptoms in later life., Britis Jounal of Psychiatry, 2018, p1 - 7 Journal Article, 2018 DOI URL

Grey T, Xidous D, Kennelly S, Timmons S, O'Neill D, Dementia friendly hospitals from a Universal Design Approach: research and guidelines, Innovations in Aging, GSA 2018 Annual Scientific Meeting, Boston, 13-17 Nov 2018, 2, (Suppl 1), 2018, pp943 Meeting Abstract, 2018 URL DOI

Briggs R, Carey D, McNicholas T, Claffey P, Nolan H, Kennelly SP, Kenny RA, The association between antidepressant use and orthostatic hypotension in older people: a matched cohort study., Journal of the American Soc Hypertension, 2018 Journal Article, 2018 DOI URL

Briggs R, Tobin K, Kenny RA, Kennelly SP, What is the prevalence of untreated depression and death ideation in older people? Data from the Irish Longitudinal Study on Aging., International Psychogeriatrics, 2018 Journal Article, 2018 URL DOI

Rashwan, W., Habib, H., Arisha, A., Courtney, G., Kennelly, S., An integrated approach of multi-objective optimization model for evaluating new supporting program in irish hospitals, Proceedings - Winter Simulation Conference, 2017, p1904-1915 Journal Article, 2017

Subbe CP, Kellett J, Barach P, Chaloner C, Cleaver H, Cooksley T, Korsten E, Croke E, Davis E, De Bie AJ, Durham L, Hancock C, Hartin J, Savijn T, Welch J; Crisis Checklist Collaborative, Crisis checklists for in-hospital emergencies: expert consensus, simulation testing and recommendations for a template determined by a multi-institutional and multi-disciplinary learning collaborative., BMC health services research, 2017 Journal Article, 2017 DOI

Peeters, G. and Leahy, S. and Kennelly, S. and Kenny, R.A., Is Fear of Falling Associated With Decline in Global Cognitive Functioning in Older Adults: Findings From the Irish Longitudinal Study on Ageing, Journal of the American Medical Directors Association, 2017, p1-10 Journal Article, 2017 DOI

Devenney KE, Sanders ML, Lawlor B, Olde Rikkert MGM, Schneider S; NeuroExercise Study Group, The effects of an extensive exercise programme on the progression of Mild Cognitive Impairment (MCI): study protocol for a randomised controlled trial., BMC Geriatrics, 17, (1), 2017, p75- Journal Article, 2017 URL DOI

Briggs R, Kenny R.A, Kennelly S.P, Does baseline hypotension predict incident depression in a cohort of community-dwelling older people? Data from The Irish Longitudinal Study on Ageing (TILDA), Age and Ageing, 46, (4), 2017, p648 - 653 Journal Article, 2017 DOI URL TARA - Full Text

Dyer, A.H., Briggs, R., Nabeel, S., O'Neill, D., Kennelly, S.P., The abbreviated mental test 4 for cognitive screening of older adults presenting to the Emergency Department, European Journal of Emergency Medicine, 24, (6), 2017, p417-422 Journal Article, 2017

Grey T, Kennelly S, de Freine P, Mahon S, Mannion V, O'Neill D, Towards a building typology and terminology for Irish hospitals, Irish Journal of Medical Science, 2017 Journal Article, 2017 DOI URL

Briggs R, Coughlan T, Doherty J, Collins DR, O'Neill D, Kennelly SP, Investigation and diagnostic formulation in patients admitted with transient loss of consciousness. , Ir Med J, 110, (5), 2017, p563 Journal Article, 2017 URL

McCarthy, H., Kennelly, S., Crawford, F., Mullan, M., Cregg, F., Lawlor, B.A., Of dementia: An overview, Drugs of the Future, 42, (5), 2017, p281-284 Journal Article, 2017

Fitzpatrick D, Ibrahim E, Kennelly S, O'Neill D, Sherlock M, Structuring diabetes mellitus care in long term nursing home residents, European Geriatric Medicine, 13th International Congress of the European Geriatric Medicine Society, Nice, 20-22 Sept 2017, 8, (Suppl 1), 2017, pps140 Meeting Abstract, 2017

Fallon A, Kennelly S, O'Neill D, Frailty in Emergency Departments, Lancet, 87, (10029), 2016, p1720 Journal Article, 2016 DOI URL

Meulenbroek O, O'Dwyer S, De Jong D, Van Spijker G, Kennelly S, Cregg F, Rikkert M.O, Abdullah L, Wallin A, Walsh C, Coen R, Kenny R.A, Daly L, Segurado R, Borjesson-Hanson A, Crawford F, Mullan M, Lucca U, Banzi R, Pasquier F, Breuilh L, Riepe M, Kalman J, Molloy W, Tsolaki M, Howard R, Jessica Adams M.O, Gaynor S, Lawlor B, European multicentre double-blind placebo-controlled trial of Nilvadipine in mild-to-moderate Alzheimer's disease - The substudy protocols: NILVAD frailty; NILVAD blood and genetic biomarkers; NILVAD cerebrospinal fluid biomarkers; NILVAD cerebral blood flow, BMJ Open, 6, (7), 2016 Journal Article, 2016 URL TARA - Full Text DOI

Allen N, Bergin C, Kennelly SP., Malaria in the returning older traveler., 2016 Journal Article, 2016 DOI URL

Briggs R, Dyer A, Nabeel S, Collins R, Doherty J, Coughlan T, O'Neill D, Kennelly SP, Dementia in the Acute Hospital: The prevalence and clinical outcomes of acutely unwell patients with dementia., QJM : monthly journal of the Association of Physicians, 2016 Journal Article, 2016 URL DOI

Timmons S, O'Shea E, O'Neill D, Gallagher P, de Siún A, McArdle D, Gibbons P, Kennelly S, Acute hospital dementia care: results from a national audit., BMC geriatrics, 16, (1), 2016, p113 Journal Article, 2016 URL DOI

Briggs R, Kennelly SP, O'Neill D, Drug treatments in Alzheimer's disease., Clinical medicine (London, England), 16, (3), 2016, p247-53 Journal Article, 2016 DOI URL

Gallagher P, Curtin D, de Siún A, O'Shea E, Kennelly S, O'Neill D, Timmons S, Antipsychotic prescription amongst hospitalized patients with dementia., QJM : monthly journal of the Association of Physicians, 2016 Journal Article, 2016 URL DOI

Briggs R, Coary R, Collins R, Coughlan T, O'Neill D, Kennelly SP, Acute hospital care: How much activity is attributable to caring for patients with dementia?, QJM : monthly journal of the Association of Physicians, 109, (1), 2016, p41 - 44 Journal Article, 2016 DOI URL

Briggs R, Kenny R.A, Kennelly S.P, Systematic Review: The Association between Late Life Depression and Hypotension, Journal of the American Medical Directors Association, 17, (12), 2016, p1076 - 1088 Journal Article, 2016 URL DOI

Miller, A.M., Begley, E., Coen, R.F., Doyle, M., Dunne, J., Hutchinson, S., Kennelly, S.P., Kenny, R.A., Killeen, R.P., O'Dwyer, S., O'Neill, C., O'Sullivan, S.S., Rowan, M.J., Sheehy, N., McGuigan, C., Lawlor, B.A. , Clinical consensus guidelines on the application of cerebrospinal fluid biomarkers for Alzheimer's disease diagnosis: recommendations of the Irish Network for Biomarkers in Neurodegeneration., Irish Medical Journal, 109, (10), 2016, p1-13 Journal Article, 2016 URL

Dyer AH, Nabeel S, Briggs R, O'Neill D, Kennelly SP, Cognitive assessment of older adults at the acute care interface: the informant history., Postgraduate medical journal, 2016 Journal Article, 2016 DOI URL

Briggs R, O'Shea E, de Siún A, O'Neill D, Gallagher P, Timmons S, Kennelly S, Does admission to a specialist geriatric medicine ward lead to improvements in aspects of acute medical care for older patients with dementia?, International journal of geriatric psychiatry, 2016 Journal Article, 2016 DOI URL

Lawlor B, Kennelly S, O'Dwyer S., NILVAD protocol: a European multicenter double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease., 2016 Journal Article, 2016

Dyer AH, Briggs R, Nabeel S, O'Neill D, Kennelly SP, The Abbreviated Mental Test 4 for cognitive screening of older adults presenting to the Emergency Department., European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2016 Journal Article, 2016 DOI URL

Fallon A, Armstrong J, Coughlan T, Collins DR, O'Neill D, Kennelly SP, Characteristics and Outcomes of Older Patients Attending an Acute Medical Assessment Unit., Irish medical journal, 108, (7), 2015, p210-1 Journal Article, 2015 URL

O'Shea E, Timmons S, Kennelly S, Siún A, Gallagher P, O'Neill D, Symptom Assessment for a Palliative Care Approach in People With Dementia Admitted to Acute Hospitals: Results From a National Audit., Journal of geriatric psychiatry and neurology, 2015 Journal Article, 2015 DOI URL

Lawlor B, Kennelly S, O'Dwyer S., Correction. NILVAD protocol: a European multicenter double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease., BMJ Open, 5, (9), 2015, pe006364 Journal Article, 2015 DOI

Lawlor B, Kennelly S, O'Dwyer S., Correction. NILVAD protocol: a European multicenter double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease., BMJ Open, 5, (9), 2015, pe006364 Journal Article, 2015 DOI

McCabe JJ, Kennelly SP., Acute care of older patients in the emergency department: strategies to improve patient outcomes., 2015 Journal Article, 2015 DOI URL

McCabe, J.J., Kennelly, S.P., Acute treatment of elderly patients in the emergency department: Strategies to improve patient outcomes | Akutbehandlung von älteren Patienten in der Notaufnahme: Strategien zur Verbesserung des Patienten-Outcome, Journal fur Anasthesie und Intensivbehandlung, (3), 2015, p23-32 Journal Article, 2015

Lawlor B, Kennelly S, O'Dwyer S., Correction. NILVAD protocol: a European multicenter double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease., BMJ Open, 5, (9), 2015, pe006364 Journal Article, 2015 DOI

O'Connell, H., Kennelly, S.P., Cullen, W., Meagher, D.J., Managing delirium in everyday practice: Towards cognitive-friendly hospitals, Advances in Psychiatric Treatment, 20, (6), 2014, p380-389 Journal Article, 2014

Grace AR, Briggs R, Kieran RE, Corcoran RM, Romero-Ortuno R, Coughlan TL, O'Neill D, Collins R, Kennelly SP., A comparison of beers and STOPP criteria in assessing potentially inappropriate medications in nursing home residents attending the emergency department., 2014 Journal Article, 2014 URL DOI

Kennelly SP, Drumm B, Coughlan T, Collins R, O'Neill D, Romero-Ortuno R, Characteristics and outcomes of older persons attending the emergency department: a retrospective cohort study., QJM, 2014 Journal Article, 2014 TARA - Full Text DOI

Lawlor B, Kennelly S, O'Dwyer S, Cregg F, Walsh C, Coen R, Kenny RA, Howard R, Murphy C, Adams J, Daly L, Segurado R, Gaynor S, Crawford F, Mullan M, Lucca U, Banzi R, Pasquier F, Breuilh L, Riepe M, Kalman J, Wallin A, Borjesson A, Molloy W, Tsolaki M, Olde Rikkert M, 'NILVAD protocol: a European multicentre double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease.', 2014, - e006364 Protocol or guideline, 2014 DOI TARA - Full Text

Kennelly SP., Cognitive dysfunction: an important extrahepatic manifestation of hepatitis C infection?, 2013 Journal Article, 2013 URL DOI

Kennelly SP, Morley D, Coughlan T, Collins R, Rochford M, O'Neill D, Knowledge, skills and attitudes of doctors towards assessing cognition in older patients in the emergency department., Postgraduate medical journal, 89, (1049), 2013, p137-41 Journal Article, 2013 TARA - Full Text DOI

Morley D, McNamara P, Kennelly S, McMahon G, Bergin C, Limitations to the identification of HIV-associated neurocognitive disorders in clinical practice., HIV medicine, 14, (8), 2013, p497-502 Journal Article, 2013

Briggs R, Coughlan T, Collins R, O'Neill D, Kennelly SP, Nursing home residents attending the emergency department: clinical characteristics and outcomes., QJM : monthly journal of the Association of Physicians, 2013 Journal Article, 2013 DOI TARA - Full Text

Bradley D, Cronin S, Kinsella JA, Tobin WO, Mahon C, O'Brien M, Lonergan R, Cooney MT, Kennelly S, Collins DR, O'Neill D, Coughlan T, Smyth S, McCabe DJ, Frequent inaccuracies in ABCD(2) scoring in non-stroke specialists' referrals to a daily Rapid Access Stroke Prevention service., Journal of the Neurological Sciences, 332, (1-2), 2013, p30-4 Journal Article, 2013 DOI TARA - Full Text URL

Kennelly S, Abdullah L, Kenny RA, Mathura V, Luis CA, Mouzon B, Crawford F, Mullan M, Lawlor B., 64. Apolipoprotein E genotype-specific short-term cognitive benefits of treatment with the antihypertensive nilvadipine in Alzheimer's patients--an open-label trial., 2012 Journal Article, 2012

O'Toole R, O'Neill D, Collins DR, Coughlan T, Kennelly S, Risk of Rehospitalisation from an 'Off-Site' Rehabilitation Unit for Older Adults, Ir Med J, 105, (8), 2012, p285 Journal Article, 2012 URL

Kennelly S, Collins O, Walking the cognitive "minefield" between high and low blood pressure., Journal of Alzheimer's disease : JAD, 32, (3), 2012, p609-21 Journal Article, 2012

Kennelly S, Abdullah L, Kenny RA, Mathura V, Luis CA, Mouzon B, Crawford F, Mullan M, Lawlor B, Apolipoprotein E genotype-specific short-term cognitive benefits of treatment with the antihypertensive nilvadipine in Alzheimer's patients--an open-label trial., International Journal of Geriatric Psychiatry, 27, (4), 2012, p415-422 Journal Article, 2012 DOI

Kennelly S, O'Neill D, O'Brien JG, Elder abuse in residential care, Lancet, 377, (9771), 2011, p1076 Journal Article, 2011 DOI

Kennelly SP, Abdullah L, Paris D, Parish J, Mathura V, Mullan M, Crawford F, Lawlor BA, Kenny RA, Demonstration of safety in Alzheimer's patients for intervention with an anti-hypertensive drug Nilvadipine: results from a 6-week open label study., International journal of geriatric psychiatry, 26, (10), 2011, p1038-45 Journal Article, 2011

Kennelly SP, Lawlor BA, Kenny RA, Blood pressure and the risk for dementia: a double edged sword., Ageing Research Reviews, 8, (2), 2009, p61-70 Journal Article, 2009 DOI

Kennelly SP, Lawlor BA, Kenny RA, Blood pressure and dementia - a comprehensive review., Therapeutic advances in neurological disorders, 2, (4), 2009, p241-60 Journal Article, 2009

Kennelly S, Sweeney N, O'Neill D, Elder abuse: knowledge, skills, and attitudes of healthcare workers., Irish medical journal, 100, (1), 2007, p326 Journal Article, 2007

Kennelly S, O'Neill D, Falls and mobility limitations in older people: measures of higher cerebral integration are also important, Am J Med, 117, (12), 2004, p971 - 971 Journal Article, 2004 URL

Non-Peer-Reviewed Publications

McCarron, M., Daly, L., McCallion, P., Allen, A.P., Buttery, N., Dennehy, H., Kennelly, S., Corr, C., Dunne, P., McGlinchey, E., Post-Diagnostic Dementia Support Guidelines for People with an Intellectual Disability, 17, Trinity College Dublin, March, 2024 Report, 2024 DOI TARA - Full Text

McCarron, M., Allen, A.P., Buttery, N., Dennehy, H., Kennelly, S., Corr, C., Dunne, P., Daly, L., McCallion P., McGlinchey, E., Voices of Experience: Building Post-Diagnostic Dementia Support Guidelines for People with an Intellectual Disability. Brief Report, 5, Trinity College Dublin, January, 2024 Report, 2024 DOI TARA - Full Text

Research Expertise

Description

Dementia Prevention Clinical Trials in Dementia Brain Health Digital Biomarkers of ageing and cognitive decline Dementia in Down Syndrome Changes in Inflammatory System and Vaccine responses within the context of ageing and frailty. Biology of Ageing research

Projects

  • Title
    • Dementia Research Network Ireland
  • Summary
    • Interdisciplinary Dementia Research Network
  • Funding Agency
    • HRB
  • Date From
    • 01/2021
  • Date To
    • 01/2024
  • Title
    • Dementia Trials Ireland
  • Summary
    • Irelands First Clinical Trial Network for Dementia
  • Funding Agency
    • HRB
  • Date From
    • 06/2021
  • Date To
    • 06/2026
  • Title
    • TIDE-AD: Translating Inflammatory Biomarkers to Predict Disease Progression & Adverse Events in Alzheimer Disease
  • Summary
    • TIDE-AD: Translating Inflammatory Biomarkers to Predict Disease Progression & Adverse Events in Alzheimer Disease
  • Funding Agency
    • Meath Foundation
  • Date From
    • 11/2021
  • Date To
    • 11/2023
  • Title
    • Supporting Tallaght University Hospital's (TUH) Integrated Care for Older Persons Service: Identifying the common housing hazards affecting older people in South Dublin
  • Summary
    • Supporting Tallaght University Hospital's (TUH) Integrated Care for Older Persons Service: Identifying the common housing hazards affecting older people in South Dublin
  • Funding Agency
    • Meath Foundation
  • Date From
    • 11/2021
  • Date To
    • 11/2022
  • Title
    • Including best practices and the voices of experience in developing post-diagnostic dementia support guidelines for people with an intellectual disability
  • Summary
    • Including best practices and the voices of experience in developing post-diagnostic dementia support guidelines for people with an intellectual disability
  • Funding Agency
    • HRCI HRB Joint Funding Scheme 2020
  • Date From
    • 09/2022
  • Date To
    • 09/2024
  • Title
    • Transcutaneous vagus nerve stimulation in the treatment of mild Alzheimer's disease
  • Summary
    • Study investigating the feasibility of transcutaneous Vagal nerve stimulation in people with mild cognitive impairment
  • Funding Agency
    • Meath Foundation
  • Date From
    • 07/2021
  • Date To
    • 07/2023
  • Title
    • NH-COVAIR; COVID 19 in Nursing Home Residence; Predicting Disease Severity, Outcomes and Anti-Viral Immune responses
  • Summary
    • Project investigating relationship between frailty, Clinical outcomes, immunophenotype, and vaccine response in nursing home residents.
  • Funding Agency
    • Meath Foundation
  • Date From
    • 12/2020
  • Date To
    • 12/2021
  • Title
    • Including best practices and the voices of experience in developing post-diagnostic dementia support guidelines for people with an intellectual disability
  • Summary
    • Development of post-diagnostic support resource for people with intellectual disability living with dementia
  • Funding Agency
    • HRB HRCI
  • Date From
    • 09/2020
  • Date To
    • 09/2022
  • Title
    • Exploring novel biomarkers of brain health in Diabetes
  • Summary
    • Investigating the predictive value of gait and inflammatory biomarkers in identifying midlife people with T2DM at risk of cognitive decline.
  • Funding Agency
    • Meath Foundation
  • Date From
    • Sept 2019
  • Date To
    • Sept 2020
  • Title
    • A Rapid Realist Review of the Need, Design, Use and Implementation of Electronic Medication Databases in Clinical Practice at Care Transitions
  • Funding Agency
    • Meath Foundation
  • Date From
    • Sept 2019
  • Date To
    • Sept 2020
  • Title
    • BRAIN-Diabetes: Border Region Area lifestyle Intervention study for healthy Neurocognitive ageing in diabetes
  • Summary
    • Multi-domain lifestyle intervention program to prevent cognitive decline in people with Type 2 Diabetes
  • Funding Agency
    • Cross-border Healthcare Intervention Trials in Ireland Network (CHITIN)
  • Date From
    • Feb 2019
  • Date To
    • Sept 2021
  • Title
    • Investigation of early stage memory changes in memory brain networks in Alzheimer's Disease
  • Funding Agency
    • Meath Foundation
  • Date From
    • July 2017
  • Date To
    • July 2018
  • Title
    • Dementia-friendly hospitals: a focus on user centred design
  • Funding Agency
    • Meath Foundation
  • Date From
    • July 2015
  • Date To
    • December 2016
  • Title
    • Dementia Friendly Irish Hospitals: Opportunities, Barriers, Costs and Solutions
  • Funding Agency
    • Health Research Board
  • Date From
    • Nov 2015
  • Date To
    • Nov 2017
  • Title
    • Irish National Audit of Dementia
  • Funding Agency
    • Meath Foundation
  • Date From
    • July 2013
  • Date To
    • July 2014

Keywords

Ageing, Older People and Healthcare; Ageing, stroke, dementia; ALZHEIMER'S DEMENTIA; BRAIN AGEING; Brain Health in Ageing; DEMENTIA; DEMENTIA SERVICES; EARLY ONSET DEMENTIA; LEWY BODY DEMENTIA; Older Adults - ageing in place, dementia, aging and technolo; Positive Ageing