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Principal Investigators

Click a heading to see Principal Investigators within each school.

Biochemistry & Immunology


Andrew G Bowie

Prof Andrew Bowie

Professor of Innate Immunology, School of Biochemistry and Immunology

Research areas: Immune Sensing and Signalling

e: agbowie@tcd.ie | t: +353-1-896 2435
w: Prof Andrew Bowie's homepage Research Support Systems: Prof Andrew Bowie


Martin Caffrey

Prof Martin Caffrey

Personal Chair, School of Biochemistry and Immunology

Research areas: Crystallizing membrane proteins

e: martin.caffrey@tcd.ie | t: +353-1-896 4253
w: Prof Martin Caffrey's homepage Research Support Systems: Prof Martin Caffrey


Mary Canavan

Dr Mary Canavan

Assistant Professor in Immunology

Research areas: Translational Immunopathology; Innate immune regulation in Rheumatic Diseases, Disease Evolution, Immunotherapeutics and Immune Related Adverse Events

e: canavam1@tcd.ie | t: +353-1-896 1604
w: Dr Mary Canavan's homepage


Emma Creagh

Dr Emma Creagh

Lecturer, School of Biochemistry and Immunology

Research areas: Research interests in the link between Cancer and Inflammation. The role of inflammatory caspases and their target proteins in intestinal inflammation during Inflammatory Bowel Disease (IBD) and Colorectal Cancer.

e: ecreagh@tcd.ie | t: +353-1-896 2539
w: Dr Emma Creagh's homepage Research Support Systems: Dr Emma Creagh


Colm Cunningham

Dr Colm Cunningham

Research lecturer, School of Biochemistry and Immunology

Research areas: Neurodegeneration and neuroinflammation and the role of microglia in these processes

Papers:

Renata Reis, Edel Hennessy, Caoimhe Murray, Éadaoin W. Griffin and Colm Cunningham (2015) At the centre of neuronal, synaptic and axonal pathology in murine prion disease: degeneration of neuroanatomically linked thalamic and brainstem nuclei. Neuropathology and Applied Neurobiology. 2015 Feb 28. doi: 10.1111/nan.12232. [Epub ahead of print].

Cunningham, C and Hennessy E (2015) Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research. Alzheimer’s Research and Therapy. Mar 7(1): 33. doi 10.1186/s13195-015-0117-2.

Cox DJ, Field, RH, Williams DG, Baran M, Bowie AG, Cunningham C and Dunne A. (2015) DNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative disease. GLIA. May 63(5): 812-825.

Daniel H.J. Davis, Donal T. Skelly, Carol Murray, Edel Hennessy, Jordan Bowen, Samuel Norton, Carol Brayne, Terhi Rahkonen, Raimo Sulkava, David J. Sanderson, J. Nicholas Rawlins, David M. Bannerman, Alasdair M.J. MacLullich and Colm Cunningham (2015) Worsening cognitive impairment and neurodegenerative pathology progressively increase risk for delirium. Am J Geriatric Psychiatry. Apr 23(4): 403-415

Eleanor Cape, Roanna J Hall, Barbara C van Munster, Annick de Vries, Sarah EM Howie, Andrew Pearson, Scott D Middleton, Fiona Gillies, Ian R Armstrong, Tim O White, Colm Cunningham, Sophia E de Rooij, Alasdair MJ MacLullich (2014) Cerebrospinal Fluid Markers of Neuroinflammation in Delirium: a role for Interleukin-1? in delirium after hip fracture. J. Psychosom. Res. Sep 77(3): 219-225.

e: colm.cunningham@tcd.ie | t: +353-1- 896 3964
w: Dr Colm Cunningham's homepage Research Support Systems: Dr Colm Cunningham


Gavin Davey

Dr Gavin Davey

Senior Lecturer, School of Biochemistry and Immunology

Research areas: Molecular and cellular mechanisms that underlie neurodegeneration in the brain

e: gdavey@tcd.ie | t: +353-1-896 1853/896 8408
w: Dr Gavin Davey's homepage Research Support Systems: Dr Gavin Davey


Aisling Dunne

Dr Aisling Dunne

Lecturer, School of Biochemistry and Immunology

Research areas: Elucidating the mechanisms involved in TLR/NLR activation as well as the identification of novel agonists from pathogens such as Bordetella pertussis

e: aidunne@tcd.ie | t: +353-1-896 2437
w: Dr Aisling Dunne's homepage Research Support Systems: Dr Aisling Dunne


Darren Fayne

Dr Darren Fayne

Senior Research Fellow, School of Biochemistry and Immunology

Research areas: Computer-Aided Drug Design. His research focus is the rational computational design of novel small molecular modulators of key disease related proteins

e: fayned@tcd.ie | t: +353-1-896 3527
w: Dr Darren Fayne's homepage Research Support Systems: Dr Darren Fayne


David Finlay

Dr. David Finlay

Associate Professor in Immunometabolism, School of Biochemistry and Immunology

Research areas: Immunometabolism, nutrient signalling, cancer immunotherapy.

e: finlayd@tcd.ie | t: +353-1-896 3564
w: Dr. David Finlay's homepage Research Support Systems: Dr David Finlay


Jean Fletcher

Dr Jean Fletcher

Lecturer, School of Biochemistry and Immunology

Research areas: Immune regulation in human disease

e: fletchj@tcd.ie | t: +353-1-896 4437
w: Dr Jean Fletcher's homepage Research Support Systems: Dr Jean Fletcher

Clair Gardiner

Dr Clair Gardiner

Senior Lecturer, School of Biochemistry and Immunology

Research areas: How human NK cells mediate their functions as part of the overall immune response

e: gardinec@tcd.ie | t: +353-1-896 1614
w: Dr Clair Gardiner's homepage Research Support Systems: Dr Clair Gardiner


Vincent P Kelly

Dr Vincent Kelly

Lecturer, School of Biochemistry and Immunology

Research areas: The role of transfer RNA (tRNA) modifications and their role in eukaryotic development and cancer

e: kellyvp@tcd.ie | t: +353-1-896 3507
w: Dr Vincent Kelly's homepage Research Support Systems: Dr Vincent Kelly


Amir Khan

Dr Amir Khan

Lecturer, School of Biochemistry and Immunology

Research areas: X-Ray Crystallography .

e: amirrafk@tcd.ie | t: +353-1-896 3868
w: Dr Amir Khan's homepage Research Support Systems: Dr Amir Khan


Ed Lavelle

Dr Ed Lavelle

Lecturer, School of Biochemistry and Immunology

Research areas: Vaccine adjuvants and mucosal vaccine development

e: lavellee@tcd.ie | t: +353-1-896 2488
w: Dr Ed Lavelle's homepage Research Support Systems: Dr Ed Lavelle


David Loane

David Loane

Research Assistant Professor

Research areas: Traumatic brain injury, neuroimmunology, microglia, aging, neuroinflammation, neurodegeneration, systemic immunity

e: loanedj@tcd.ie | t: +353-1-896 1616
w: David Loane's homepage


Lydia Lynch

Dr Lydia Lynch

Associate Professor in Immunology

Research areas: We are interested in the effects of obesity and diet on immune cell functions, particularly innate cells including iNKT cells, NK cells and gamma delta T cells. The Lynch lab also studies the role of the immune system in the regulation of metabolism and body weight, particularly the local immune system in adipose tissue in mice and humans

e: LYNCHL3@tcd.ie | t: +353-1-896 1615
w: Dr Lydia Lynch's homepage w: Dr Lydia Lynch's Lab


Rachel McLoughlin

Dr Rachel McLoughlin

Lecturer, School of Biochemistry and Immunology

Research areas: Understanding the interaction of bacteria and the molecules they express, with the host's immune system

e: rachel.mcloughlin@tcd.ie | t: +353-1-896 2526
w: Dr Rachel McLoughlin's homepage Research Support Systems: Dr Rachel McLoughlin


Kingston Mills

Prof. Kingston Mills

Professor, School of Biochemistry and Immunology

Research areas: T cells and immune regulation, relevant to infection, autoimmunity and cancer.

e: kingston.mills@tcd.ie | t: +353-1-896 3573
w: Prof. Kingston Mills's homepage Research Support Systems: Prof. Kingston Mills


Kenneth H Mok

Dr Ken Hun Mok

Lecturer, School of Biochemistry and Immunology

Research areas: Probing the attainment of natively- or alternatively- folded three-dimensional molecular structures

e: mok1@tcd.ie | t: +353-1-896 3190
w: Dr Ken Hun Mok 's homepage Research Support Systems: Dr Ken Mok


Derek Nolan

Dr Derek Nolan

Lecturer, School of Biochemistry and Immunology

Research areas: Molecular Parasitology

e: denolan@tcd.ie | t: +353-1-896 2455
w: Dr Derek Nolan's homepage Research Support Systems: Dr Derek Nolan


Cliona O'Farrelly

Prof Cliona O'Farrelly

Chair in Comparative Immunology, School of Biochemistry and Immunology

Research areas: Regional Immunity: Role in Liver, Gut &Uterine Pathology. Comparative Immunology

e: cliona.ofarrelly@tcd.ie | t: +353-1-896 3175
w: Prof Cliona O'Farrelly's homepage Research Support Systems: Prof Cliona O'Farelly


Luke O'Neill

Prof. Luke O'Neill

Chair Of Biochemistry, School of Biochemistry and Immunology, School of Biochemistry and Immunology

Research areas: Innate immunity and inflammatory diseases.

e: laoneill@tcd.ie | t: +353-1-896 2439
w: Prof. Luke O'Neill's homepage Research Support Systems: Prof. Luke O'Neill


Richard K Porter

Dr Richard Porter

Senior Lecturer, School of Biochemistry and Immunology

Research areas: The molecular basis of basal metabolic rate and how metabolism is controlled in mammals

e: rkporter@tcd.ie | t: +353-1-896 1617
w: Dr Richard Porter's homepage Research Support Systems: Dr Richard Porter


Tomás Ryan

Tomás Ryan

Associate Professor, Biochemistry Associate Professor, Trinity Inst. of Neurosciences (TCIN)

Research areas: ENGRAM; Evolution; MEMORY

e: tryan6@tcd.ie | t: +353-1-896 1574
w: Tomás Ryan's Lab w: Tomás Ryan's homepage


Nigel Stevenson

Dr Nigel Stevenson

Assistant Professor of Viral Immunology and Director of the M.Sc in Immunology

Research areas: Intracellular Immunology. The main focus of the Intracellular Immunology group is to understand the mechanisms by which pathogens target and evade molecular and cellular immune responses.

e: N.Stevenson@tcd.ie | t: +353-1-896 1574
w: Dr Nigel Stevenson's homepage Research Support Systems: Dr Nigel Stevenson


Daniela Zisterer

Dr Daniela Zisterer

Senior Lecturer , School of Biochemistry and Immunology

Research areas: Molecular and cellular mechanisms that underlie apoptotic cell death and in understanding how deregulated apoptosis leads to cancer

e: dzistrer@tcd.ie | t: +353-1-896 1628
w: Dr Daniela Zisterer's homepage Research Support Systems: Dr Daniela Zisterer

Biomedical Engineering


Mark Ahearne

Prof Mark Ahearne

Assistant Professor in Biomedical Engineering, School of Engineering

Research areas: Prof. Mark Ahearne primary research interests involve developing novel approaches to restoring vision by using a combination of tissue engineering, advanced biomaterials and stem cell technologies. Specific studies have examined the role of biochemical and biophysical cues on modulating corneal cell behaviour; the fabrication of electrospun nanofiber scaffolds, silk fibroin substrates, decellularized scaffolds and extracellular matrix derived hydrogels for use as biomimetic implants; the development of ocular organ culture models to evaluate implants and the application of adipose derived stem cells for cornea repair. His research has been supported by funding from European Research Council (ERC), Science Foundation Ireland (SFI), Marie-Curie Actions and European Cooperation in Science and Technology (COST).

e: AHEARNM@tcd.ie | t: +353 1 8964214
w: Prof Mark Ahearne's homepage Research Support Sytems: Prof Mark Ahearne


Conor Buckley

Prof Conor Buckley

Professor in Biomedical Engineering, School of Engineering

Research areas: The focus of the Buckley lab is to develop novel biomaterial and cell based strategies to regenerate or repair damaged tissues and restore biomechanical function using minimal invasive strategies. Specific research interests include Intervertebral Disc, Cartilage, Peripheral Nerve Tissue Engineering; Advanced Injectable Hydrogel Biomaterials; Decellularised Tissues and Matrices; Biofabrication, 3D Printing and Bioprinting; Cellular Microencapsulation, Tissue Spheroids for Therapeutic Regeneration; Cell Priming, Cryopreservation & Transportation Strategies; In Silico Predictive Modelling of Microenvironments for Personalised Medicine

e: conor.buckley@tcd.ie | t: +353 1 896 2061
w: Prof Conor Buckley's homepage Research Support Systems: Prof Conor Buckley


 David Hoey

Prof David Hoey

Associate Professor in Biomedical Engineering, School of Engineering

Research areas: Prof. David Hoey is an Associate Professor in the Dept. of Mechanical, Manufacturing, and Biomedical Engineering and Director of the Biomedical Engineering program. Dr. Hoey leads a multidisciplinary research team in the area of musculoskeletal mechanobiology and materials for regeneration within the Trinity Centre for Biomedical Engineering and the Advanced Materials and Bioengineering Research (AMBER) Centre. His research focus is to delineate the importance of mechanics in musculoskeletal physiology and utilise this fundamental information to inform the development of novel therapeutics, biomaterials, and biofabrication technologies for tissue regeneration/replacement. His team has made significant advancements in understanding the mechanisms by which biophysical stimuli are transduced by cells and has targeted these mechanisms utilising novel mechano-therapeutics to treat orthopaedic diseases such as osteoporosis. He has been awarded >€3.4million in funding including two European Research Council awards (Starter grant 2013; PoC grant 2019) and a SFI Frontiers for the Future grant (Project 2020).

e: dahoey@tcd.ie | t: +353 1 8961359
w: Prof David Hoey's homepage w: Prof David Hoey's Lab Research Support Sytems:


Daniel Kelly

Prof Daniel Kelly

Professor of Tissue Engineering, School of Engineering

Research areas: Prof. Kelly leads a multidisciplinary musculoskeletal tissue engineering group based in the Trinity Centre for Biomedical Engineering. The goal of his laboratory is to understand how environmental factors regulate the fate of adult stem cells. This research underpins a more translational programme aimed at developing novel tissue engineering and 3D bioprinting strategies to regenerate damaged and diseased musculoskeletal tissues. To date he has published over 180 articles in peer-reviewed journals and secured over €18 million in research funding. He is the recipient of four European Research Council awards (Starter grant 2010; Consolidator grant 2015; Proof of Concept grant 2017; Advanced grant 2021).

e: kellyd9@tcd.ie | t: +353 1 8963947
w: Prof Daniel Kelly's homepage Research Support Systems: Prof Daniel Kelly


Caitriona Lally

Prof Caitríona (Tríona) Lally

Professor in Biomedical Engineering, School of Engineering

Research areas: The Lally lab is focused on arterial tissue mechanics, vascular imaging, vascular mechanobiology and tissue engineering. We aim to gain critical insights into the role of mechanics in cardiovascular diseases, with particular focus on load induced remodelling and regeneration of arterial tissues at the material and cell level. Using non-invasive vascular imaging techniques, such as Diffusion Tensor Magnetic Resonance Imaging, we aim to develop novel diagnostic techniques for early detection of vascular degeneration. We also use in vitro and in silico modeling approaches to aid the design and development of intravascular medical devices for the treatment of existing vascular disease. Prof. Lally joined the Department of Mechanical & Manufacturing Engineering in Trinity College Dublin in 2015. She has secured considerable research funding from SFI, Enterprise Ireland and the IRC and was awarded an ERC starting grant in 2014.

e: lallyca@tcd.ie | t: +353 1 8963159
w: Prof Caitríona Lally's homepage Research Support Sytems: Prof Caitríona Lally


Michael Monaghan

Dr Michael Monaghan

Ussher Assistant Professor in Biomedical Engineering, School of Engineering

Research Areas: biomaterials, gene therapy, cardiac tissue engineering, melt electrowriting, tissue engineering, disease-in-a-dish in vitro models, electroconductive biomaterials, non-invasive biomedical imaging (fluorescent lifetime imaging microscopy (FLIM), multiphoton microscopy, second harmonic generation (SHG)), metabolic profiling of microenvironments

e: monaghmi@tcd.ie | t: +353 1 896 8582
w: Monaghan Lab Homepage Research Support Sytems: Dr Michael Monaghan


Bruce Murphy

Prof Bruce Murphy

Associate Professor in Biomechanical Engineering, School of Engineering

Research areas: My lab designs and develops new medical devices that solve unmet clinical needs. The research is funded by Enterprise Ireland, EIT health, HRB and SFI. Four recent spin-outs from the lab have cumulatively raised over €50M and employ over 50 full time equivalent employees. The companies are Proverum Medical, Selio Medical, CroiValve Ltd and OneProjects

e: bruce.murphy@tcd.ie | t: +353 1 8968503
w: Prof Bruce Murphy's homepage Research Support Systems: Prof Bruce Murphy


Ciaran Simms

Prof Ciaran Simms

Professor in Biomechanics, School of Engineering

Research areas: The focus of the Simms Lab is to understand how external forces load internal body structures, to enable design of improved devices/processes in injury biomechanics applications. We work on three strands: soft tissue mechanics (especially the structure-loading relationship in passive muscle), pedestrian/cyclist collisions (protection remains a challenge) and sports injuries (increasing importance and sporting collisions are a living laboratory).

e: csimms@tcd.ie | t: +353 1 8963768
w: Prof Ciaran Simms's homepage Research Support Systems: Prof Ciaran Simms

Chemistry


Stephen Connon

Prof. Stephen Connon

Professor in Synthetic Chemistry, School of Chemistry

Research areas: Cancer Chemotherapy, Catalysis, Cyclin, Kinase Complex, Organic-Synthesis, Organometallics, Tetracycline

e: connons@tcd.ie | t: +353 1 896 1306
w: Prof. Stephen Connon's homepage Research Support Systems: Prof. Stephen Connon


David Grayson

Prof. David Grayson

Emeritus Professor, School of Chemistry

Research areas: Synthesis of medium-ring and macrocyclic lactones; chemistry of sulfonyl compounds

e: dgrayson@tcd.ie | t: +353 1 896 2021
w: Prof. David Grayson's homepage Research Support Systems: Prof. David Grayson


Thorfinnur Gunnlaugsson

Prof. Thorfinnur Gunnlaugsson

Senior Sophister Coordinator, School of Chemistry

Research areas: Cancer Research

e: thorri.g@tcd.ie | t: +353 1 896 3459
w: Prof. Thorfinnur Gunnlaugsson's homepage w: TCD profile Research Support Systems: Prof. Thorfinnur Gunnlaugsson


Aidan McDonald

Dr. Aidan McDonald

Royal Society/SFI University Research Fellow and Associate Professor of Inorganic Chemistry

Research areas: bioinorganic chemistry; oxygenases; ribonucleotide reductases; synthetic inorganic chemistry; inorganic reaction mechanisms; catalysis

e: aidan.mcdonald@tcd.ie | t: +353 1 896 4546
w: Dr. McDonald's homepage Research Support Systems: Dr Aidan McDonald


Joanna McGouran

Dr Joanna McGouran

Schuler Assistant Professor in Translational Organic Chemistry, School of Chemistry

Research areas: : Bio-organic chemistry, nucleic acid chemistry, protein modification, enzyme inhibition, activity based proteomics, proteolysis, DNA damage repair

e: jmcgoura@tcd.ie | t: +353 1 896 1422
w: Dr McGouran's homepage Research Support Systems: Dr Joanna McGouran


Kim McKelvey

Kim McKelvey

Assistant Professor, Chemistry

Research areas: : Nanoscale electrochemistry to study energy storage and conversion technologies

e: kim.mckelvey@tcd.ie | t: +353 1 896 1422
w: Kim McKelvey's homepage Research Support Systems: Kim McKelvey


Isabel Rozas

Prof. Isabel Rozas

Associate Professor , Director of Teaching and Learning (Postgraduate), School of Chemistry

Research areas: Cancer Research

e: rozasi@tcd.ie | t: +353 1 896 3731
w: Prof. Isabel Rozas's homepage Research Support Systems: Prof. Isabel Rozas


Eoin Scanlan

Prof. Eoin Scanlan

Lecturer, International Coordinator, School of Chemistry

Research areas: Development of novel synthetic methodology for the construction of oligosaccharides and glycoconjugates, the synthesis of carbohydrate-based therapeutics for treatment of diseases, the synthesis of immunogenic carbohydrates and the synthesis of glycoconjugates for bio-imaging

e: eoin.scanlan@tcd.ie | t: +353 1 896 2514
w: Prof Eoin Scanlan's homepage Research Support Systems: Prof. Eoin Scanlan


Mathias O. Senge

Prof. Dr. Mathias O. Senge

Chair of Organic Chemistry (2001), Head, Discipline of Organic, Medicinal and Biological Chemistry, School of Chemistry

Research areas: Bioorganic and biological chemistry; heterocyclic and natural product chemistry; synthetic organic chemistry; medicinal chemistry: photodynamic cancer therapy; photobiology; crystallography; tetrapyrroles; history of chemistry and photomedicine

e: sengem@tcd.ie | t: +353 1 896 8537
w: Prof. Mathias O. Senge's homepage Research Support Systems: Prof. Mathias O. Senge


Mike Southern

Prof. Michael Southern

Lecturer in Chemistry (Medicinal/Organic) Course Director of the B.A. (Mod) in Chemistry, School of Chemistry

Research areas: Drug discovery and development, neurochemistry, the interface of chemistry and biology and synthetic organic chemistry

e: southerj@tcd.ie | t: +353 1 896 3411
w: Prof Michael Southern's homepage Research Support Systems: Prof Mike Southern

Medicine


Martin Caffrey

Prof Martin Caffrey

Personal Chair, School of Biochemistry and Immunology

Research areas: Crystallizing membrane proteins

e: martin.caffrey@tcd.ie | t: +353-1-896 4253
w: Prof Martin Caffrey's homepage Research Support Systems: Prof Martin Caffrey


Mary Canavan

Dr Mary Canavan

Assistant Professor in Immunology

Research areas: Translational Immunopathology; Innate immune regulation in Rheumatic Diseases, Disease Evolution, Immunotherapeutics and Immune Related Adverse Events

e: canavam1@tcd.ie | t: +353-1-896 1604
w: Dr Mary Canavan's homepage


Suzanne Cloonan

Professor Suzanne Cloonan

Associate Professor in Respiratory Biochemistry

Research Area: Mitochondria and iron metabolism in chronic and acute lung disease with a focus on alveolar macrophages and alveolar epithelial cells

e: suzanne.cloonan@tcd.ie | t:
w: Professor Cloonan's homepage

Research Support Systems: Professor Suzanne Cloonan


Kumlesh Dev

Prof. Kumlesh Dev

Professor of Neuroscience, School of Medicine

Research areas: Drug Development, Neurology, Demyelinating Diseases, Multiple Sclerosis, Neuroimmunology, Receptor Biology, Sphingosine 1-phosphate Receptors

e: devk@tcd.ie | t: +353 1 896 4180
w: Prof. Kumlesh Dev's homepage Research Support Systems: Prof. Kumlesh Dev


Seamas Donnelly

Prof. Seamas Donnelly

Professor of Medicine, School of Medicine

Research areas: Pathogens and Toll Like Receptors, Design novel anti-cancer/anti-inflammatory compounds, Design novel nano-packaged inhalation therapies, Neural Inflammatory Reflex and The Microbiome in Health & Disease

e: seamas.donnelly@tcd.ie | t: +353 1 896 3844
w: Prof. Seamas Donnelly's homepage


Eric Downer

Dr. Eric Downer

Assistant Professor and Director B.Sc. in Human Health & Disease, School of Medicine

Research Area: Neuroimmunology; Multiple Sclerosis; Innate immune signalling; Cannabinoid pharmacology; Neuropathic orofacial pain

e: edowner@tcd.ie | t: +353 1 896 2076
w: Dr Downer's homepage Research Support Systems: Dr Eric Downer


Padraic Fallon

Prof. Padraic Fallon

Stokes Professor, School of Medicine

Research areas: My research involves two overlapping translational immunology themes. i. The use of mouse models to study pathogen modulation of human inflammatory diseases. ii. Immune phenotyping of patients, in particular children, with inflammatory diseases such as atopic dermatitis and pulmonary fibrosis. Research aims to elucidate new mechanism of modulation of immunity that can alter inflammation and have therapeutic potential. Collaborative activity involves the phenotyping of new transgenic mice. The main diseases addressed are allergic lung and skin inflammation and inflammatory bowel disease. A growing emphasis is applying extensive expertise in animal models of human inflammatory diseases and general pathophysiology of inflammation to functional analysis of new therapeutic molecules/strategies with clinical collaborators and Pharma.

e: pfallon@tcd.ie | t: +353 1 896 3267
w: Prof. Padraic Fallon's homepage Research Support Systems: Prof. Padraic Fallon


Ursula Fearon

Professor Ursula Fearon

Professor Molecular Rheumatology, School of Medicine

Research Area: Molecular Rheumatology, with specific focus on cellular invasion, hypoxia/mitochondrial dysfunction, metabolism, angiogenesis and immune dysregulation

e: fearonu@tcd.ie | t: +353 1 896 2659
w: Professor Fearon's homepage


 Jean Fletcher

Dr. Jean Fletcher

School of Medicine (Clinical Medicine)

Research Areas:Research areas: Immune regulation in human disease

e: fletchj@tcd.ie | t: +353-1-896 4437
w: Dr Jean Fletcher's homepage Research Support Systems: Dr Jean Fletcher


Orla Hardiman

Prof. Orla Hardiman

Professor of Neurology, School of Medicine

Research areas: Chronic Disease, Chronic Illness, Dementia, Disability, Neurodegeneration, Neuroimaging

e: hardimao@tcd.ie | t: +353 1 896 4496
w: Prof. Orla Hardiman's homepage Research Support Systems: Prof. Orla hardiman


Cliona O'Farrelly

Prof Cliona O'Farrelly

Chair in Comparative Immunology, School of Biochemistry and Immunology

Research areas: Regional Immunity: Role in Liver, Gut &Uterine Pathology. Comparative Immunology

e: cliona.ofarrelly@tcd.ie | t: +353-1-896 3175
w: Prof Cliona O'Farrelly's homepage Research Support Systems: Prof Cliona O'Farelly


Alice Witney

Alice Witney

School of Medicine

Research areas: Sensory-Motor Integration; Neuromodulation

e: awitney@tcd.ie | t: +353 1 8961019
w: Dr Alice Witney's homepage Research Support Systems: Dr Alice Witney

Pharmacy and Pharmaceutical Sciences


Fabio Boylan

Dr Fabio Boylan

Associate Professor, School of Pharmacy and Pharmaceutical Sciences

Research areas: Ethnopharmacological information of medicinal plants from South America, Europe and Asia. Pharmacological targets are mainly related to inflammation, pain, cancer and central nervous system.

e: fabio.boylan@tcd.ie | t: +353 1 896 4154
w: Dr Fabio Boylan's homepage Research Support Systems: Dr Fabio Boylan


Carsten Ehrhardt

Dr Carsten Ehrhardt

Associate Professor, School of Pharmacy and Pharmaceutical Sciences

Research areas: Transport mechanisms and cell physiology of alveolar and bronchial epithelial barriers and the development of advanced drug delivery systems for pulmonary targeting.

e: carsten.ehrhardt@tcd.ie | t: +353 1 896 2441
w: Dr Carsten Ehrhardt's homepage Research Support Systems: Dr Carsten Ehrhardt


David Finlay

Dr. David Finlay

Associate Professor in Immunometabolism, School of Biochemistry and Immunology

Research areas: Immunometabolism, nutrient signalling, cancer immunotherapy.

e: finlayd@tcd.ie | t: +353-1-896 3564
w: Dr. David Finlay's homepage Research Support Systems: Dr David Finlay


Neil Frankish

Dr Neil Frankish

Associate Professor, School of Pharmacy and Pharmaceutical Sciences

Research areas: Novel drug development in the areas of allergy and inflammation, with a particular interest in inflammatory bowel disease

e: nfrnkish@tcd.ie | t: +353 1 896 2825
w: Dr Neil Frankish's homepage Research Support Systems: Dr Neil Frankish


John Gilmer

Professor John Gilmer

Professor in Pharmaceutical Chemistry & Director of Teaching and Learning (postgraduate), School of Pharmacy and Pharmaceutical Sciences

Research areas: Study of chemico-biological interactions of bile acids and effects on cell viability and proliferation; mechanisms of bile acid uptake in esophageal cells; design of bile acid-based chemo-preventative and therapeutic agents; bile acid activation of GR Inhibition of tumour cell - platelet interactions by aspirin analogs and prodrugs Design of selective MMP inhibitors and hybrid inhibitors of MMP secretion Chemical approaches to targeting of COX-2 inhibitors for chemoprevention

e: gilmerjf@tcd.ie | t: +353 1 896 2795
w: Dr John Gilmer's homepage Research Support Systems: Dr John Gilmer


Carlos Medina

Dr Carlos Medina

Assistant Professor, School of Pharmacy and Pharmaceutical Sciences

Research areas: Research interests: cancer, inflammatory bowel disease, nanoparticle-based therapeutics Involvement of matrix metalloproteinases in cancer and inflammatory bowel disease

e: carlos.medina@tcd.ie | t: +353 1 896 2823
w: Dr Carlos Medina's homepage Research Support Systems: Dr Carlos Medina


Mary Meegan

Prof. Mary Meegan

Fellow Emeritus Professor in Pharmaceutical Chemistry, School of Pharmacy and Pharmaceutical Sciences

Research areas: Cancer Research

e: mmeegan@tcd.ie | t: +353 1 896 2798
w: Prof. Mary Meegan's homepage Research Support Systems: Prof. Mary Meegan


Niamh O'Boyle

Dr Niamh O'Boyle

Assistant Professor, Pharmaceutical Chemistry, School of Pharmacy and Pharmaceutical Sciences

Research areas: Medicinal chemistry, skin chemistry, cancer research, allergic contact dermatitis, drug design and development.

e: h.oboyle@tcd.ie | t: +353 1 896 2524
w: Dr Niamh O'Boyle's homepage Research Support Systems: Dr Niamh O'Boyle


Lorraine O'Driscoll

Professor Lorraine O'Driscoll

Professor in Pharmacology, School of Pharmacy and Pharmaceutical Sciences

Research areas: Translational cancer research

e: lodrisc@tcd.ie | t: +353 1 896 2822
w: Dr Lorraine O'Driscoll's homepage Research Support Systems: Dr Lorraine O'Driscoll


Eduardo Ruiz-Hernandez

Dr Eduardo Ruiz-Hernandez

Associate Professor, School of Pharmacy and Pharmaceutical Sciences

Research areas: nanomedicines, stimuli-responsive nanoparticles, injectable hydrogels

e: ruizhere@tcd.ie | t: +353 1 896 2844
w: Dr Eduardo Ruiz-Hernandez' homepage Research Support Systems: Dr Eduardo Ruiz-Hernandez


Astrid Sasse

Dr Astrid Sasse

Associate Professor in Pharmaceutical Chemistry

Research areas: Development of small ligands for G-Protein coupled receptors (e.g., histamine H3/H4 receptor) as well as the genetic linkage of those receptors to psychiatric disorders

e: sassea@tcd.ie | t: +353 1 896 2797
w: Dr Astrid Sasse's homepage Research Support Systems: Dr Astrid Sasse


Maria Jose Santos-Martinez

Dr Maria Jose Santos-Martinez

Ussher Assistant Professor in Nanopharmaceutical Drug Discovery (School of Pharmacy and Pharmaceutical Sciences & School of Medicine)

Research areas: Platelet biology and pharmacology. Contribution of platelets to cancer progression (tumor invasion, angiogenesis and blood metastastasis). Application of Quartz Crystal Microbalance with Dissipation (QCM-D) technology to platelets, cell biology and nanomaterials. Nanotoxicology: understanding nanoparticle-cell and nanoparticle-platelet interactions. Interactions between nanoparticles developed for drug delivery, their targets and the potential barriers that they have to be overcome to exert their action.

e: mariajose.santos@tcd.ie | t: +353 1 896 4281
w: Dr Maria Jose Santos-Martinez's homepage Research Support Systems: Dr Maria Jose Santos-Martinez


Helen Sheridan

Dr Helen Sheridan

Associate Professor & Director of Research, School of Pharmacy and Pharmaceutical Sciences

Research areas: Identifying problems and proposing solutions by applying functional genomic approaches; establishing guidelines and priority areas for the future

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