Molecular Parasitology
Dr Derek Nolan
Professor in Biochemistry
Course Coordinator of Junior Sophister Biochemistry
I have worked on African trypanosomes, which cause human sleeping sickness, for twenty years. As a PhD student I investigated the bioenergetics of T. brucei in Paul Voorheis' laboratory at Trinity College Dublin. Subsequently, I moved to Brussels in 1992, as an EMBO fellow, to join the group of Etienne Pays to study the expression and function of surface proteins in trypanosomes.
Conor Leahy - PhD Project 2021-2025
Aggregation of Trypanosoma brucei following the addition of IgM
Thomson Santhosh - M.Sc in Immunology Project 2024/2025
Antibody-induced disaggregation in wild-type & TbKIFC1 knockdown trypanosomes (MITat 1.1)
Tea Stapar - Senior Sophister Project 2024/25
Video 1:GK RNAi induced SHAM treatment
Video 2:GK RNAi non-induced SHAM treatment
MSc. in Immunology Project 2022/23
Video 1: T. brucei Wild type cell
Video 2: FLA2 induced - detached flagellum
Senior Sophister Project 2022/23
The African trypanosomes are extracellular parasitic protozoa responsible for sleeping sickness in humans and related diseases in domestic animals.