Selected Publications
Davis GM, Juere E, Hayes JM and Davey GP (2022) Mitochondrial complex I controls blood brain barrier permeability. bioRxiv, doi.org/10.1101/2022.10.13.512023
Benevenuto SGM, Domenico MD, Yariwake VY, Dias CT, Mendes-da-Silva C, Alves NO, Caumo SEDS, Vasconcellos P, Morais DR, Cardoso MS, Ianicelli J, Waked D, Davey GP, Boylan F, Costa JL, Veras MM. (2022) Prenatal exposure to Cannabis smoke induces early and lasting damage to the brain. Neurochem Int. 160:105406. doi: 10.1016/j.neuint.2022.105406.
McDonald AG, Mariethoz J, Davey GP, Lisacek F. (2022) In silico analysis of the human milk oligosaccharide glycome reveals key enzymes of their biosynthesis. Sci Rep. 12(1):10846. doi: 10.1038/s41598-022-14260-4.
McDonald AG, Davey GP, O-Glycologue: A Formal-Language-Based Generator of O-Glycosylation Networks, Methods Mol Biol., 2370, 2021, p223 - 236 DOI
Hayes JM, O'Hara DM, Davey GP, Metabolic Labeling of Primary Neurons Using Carbohydrate Click Chemistry, Methods Mol Biol, 2021, p315 – 322 DOI
O'Farrell LK, Fraser AD, Davey GP, Monitoring the Sialome on Human Immune Cells, Methods Mol Biol, 2370, 2021, p323 – 329 DOI
Smith J, Millán-Martín S, Mittermayr S, Hilborne V, Davey G, Polom K, Roviello F, Bones J., 2-Dimensional ultra-high performance liquid chromatography and DMT-MM derivatization paired with tandem mass spectrometry for comprehensive serum N-glycome characterization, Analytica Chimica Acta, 1179, (338840), 2021 DOI
McDonald AG and Davey GP , Simulating the enzymes of ganglioside biosynthesis with Glycologue, Beilstein Journal of Organic Chemistry, 2021 DOI
Dowling JK, Afzal R, Gearing LJ, Cervantes-Silva MP, Annett S, Davis GM, De Santi C, Assmann N, Dettmer K, Gough DJ, Bantug GR, Hamid FI, Nally FK, Duffy CP, Gorman AL, Liddicoat AM, Lavelle EC, Hess C, Oefner PJ, Finlay DK, Davey GP, Robson T, Curtis AM, Hertzog PJ, Williams BRG, McCoy CE , Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages, Nature Communications, 12, (1), 2021, p1460- DOI
Martignoni M; Benedetti M; Davey GP; Tipton KF; McDonald A, Degradation of thymic humoral factor 2 in human, rat and mouse blood: an experimental and theoretical study, BBA - Proteins and Proteomics, 2020 DOI
Abascal JF, Chiaino E, Frosini M, Davey GP, Valoti, β-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration, International Journal of Molecular Sciences, 2020 DOI
Kilbride, SM, Telford, JE and Davey, GP, Complex I controls mitochondrial and plasma membrane potentials in nerve terminals, Neurochemical Research, 2020 Notes: [doi: 10.1007/s11064-020-02990-8] DOI
Varešlija D, Tipton KF, Davey GP, McDonald AG, 6-Hydroxydopamine: a far from simple neurotoxin., J Neural Transm, 2020 DOI
Sinevici N, Mittermayer S, Davey GP, Bones J, O'Sullivan J, Salivary N-glycosyalation as a biomarker of Oral Cancer: A pilot study., Glycobiology, 2019 DOI
O’Hara D, Davis GM, Adlesic NA, Hayes JM and Davey GP (2019) Dichloroacetate Stabilizes Mitochondrial Fusion Dynamics in Models of Neurodegeneration. Front. Mol. Neurosci. 12:219. doi: 10.3389/fnmol.2019.00219
McDonald AG, Tipton KF and Davey GP (2018) A mechanism for bistability in glycosylation PLOS Computational Biology 2018 Aug 3;14(8):e1006348 (2018) doi: 10.1371/journal.pcbi.1006348
Smith J, Davey G, Polom K, Roviello F, Bones J. (2018) Mining the acidic serum proteome utilizing off-gel isoelectric focusing and label free quantitative liquid chromatography mass spectrometry. J Chromatogr A. 2018 Sep 7;1566:32-43. doi: 10.1016/j.chroma.2018.06.044
Djikic T, Martí Y, Spyrakis F, Lau T, Benedetti P, Davey G, Schloss P, Yelekci K (2018) Human dopamine transporter: the first implementation of a combined in silico/in vitro approach revealing the substrate and inhibitor specificities. J Biomol Struct Dyn. 2018 Jan 26:1-16. doi: 10.1080/07391102.2018.1426044
Hayes JM, Frostell A, Karlsson R, Müller S, Millan-Martin S, Pauers M, Reuss F, Cosgrave E, Anneren C, Davey GP and Rudd PM. (2017) Identification of Fc gamma receptor glycoforms that produce differential binding kinetics for rituximab. Molecular Cell Proteomics doi: 10.1074/mcp.M117.066944. doi: 10.1074/mcp.M117.066944
Hayes JM, Wormwald M, Rudd P and Davey GP (2016) Fc gamma receptors: glycobiology and therapeutics prospects. Journal of Inflammation Research 9, 209-219
McDonald AG, Hayes JM and Davey GP (2016) Metabolic flux control and glycosylation Current Opinion in Structural Biology 40, 97-103
McDonald AG, Tipton KF and Davey GP (2016) A knowledge-based system for display and prediction of O-glycosylation network behavior in response to enzyme knockouts. PLOS Comp Biology 12(4):e1004844. doi: 10.1371/journal.pcbi.1004844
Harte NP, Klyubin I, McCarthy EK, Min S, Garrahy SA, Xie Y, Davey GP, Boland JJ, Rowan MJ and Mok KH (2015) Amyloid oligomers and mature fibrils prepared from innocuous protein cause diverging cellular death mechanisms. Journal of Biological Chemistry, PMID: 26221033
McDonald AG, Hayes JM, Bezak T, Gluchowska SA, Cosgrave EFJ, Struwe WB, Stroop CJM, Kok H, van de Laar T, Rudd PM, Tipton KF and Davey GP (2014) Galactosyltransferase 4 is a major control point for glycan branching in N-linked glycosylation. Journal of Cell Science 1;127(23):5014-26
Hayes JM, Frostell A, Cosgrave EF, Struwe WB, Potter O, Davey GP, Karlsson R, Anneren C, Rudd PM. (2014) Fc gamma receptor glycosylation modulates the binding of IgG glycoforms: a requirement for stable antibody interactions. J Proteome Res. 2014 Dec 5;13(12):5471-85
Hayes JM, Cosgrave EFJ, Struwe WB, Wormald M, Davey GP, Jefferis R and Rudd PM (2014) Glycosylation and Fc Receptors. Current topics in Microbiology and Immunology, 382, 165-199.
Davey GP and Bolanos JP (2013) Peroxiredoxin 5 links mitochondrial redox signalling with calcium dynamics: impact on Parkinson's disease. Journal of Neurochemistry doi: 10.1111/jnc12171.
Min S, Meehan J, Sullivan LM, Harte NP, Xie Y, Davey GP, Svanborg C, Brodkorb A, Mok KH. (2012) Alternatively folded proteins with unexpected beneficial functions. Biochem Soc Trans 40, 746-751.
Burleigh, SC, van de Laar, T, Stroop, CJM, van Grunsven, WMJ, O'Donoghue, N, Rudd PM and Davey GP (2011) Synergizing metabolic flux analysis and nucleotide sugar metabolism to understand the control of glycosylation of recombinant protein in CHO cells. BMC Biotechnology, 11, 95-112.
Tipton KF, Davey GP, McDonald AG. Kinetic behaviour and reversible inhibition of monoamine oxidases-enzymes that many want dead. Int Rev Neurobiol. 2011;100:43-64.
Kilbride SM, Gluchowska SA, Telford JE, O'Sullivan C, Davey GP (2011) High-level inhibition of mitochondrial complexes III and IV is required to increase glutamate release from the nerve terminal. Molecular Neurodegeneration. 26;6(1):53.
Heales SJ, Menzes A, Davey GP (2011) Depletion of glutathione does not affect electron transport chain complex activity in brain mitochondria: Implications for Parkinson disease and post-mortem studies Free Radic Biol Med. 2011 Apr 1;50(7):899-902.
Artemenko NV, McDonald, AG, Davey, GP, Rudd, PM (2011) Databases and Tools in Glycobiology. Chapter in Therapeutic Proteins: Methods and Protocols, Methods in Molecular Biology, Eds Vladimir Voynov and Justin Caravella, Humana Press. Volume 899, 325-350.
McDonald AG, Tipton KF, Stroop CJ, Davey GP (2010) GlycoForm and GlycoLogue: two software applications for the rapid construction and display of N-glycans from mammalian sources. BMC Res Notes. 2010 Jun 18;3:173.
Sullivan S, Davey GP Reprogramming human dermal fibroblasts for the generation of pluripotent stem cells. (2010) Protocol 23.8 in Freshney, R.I., Culture of Animal Cells, a Manual of Basic Technique and Specialized Applications, Hoboken, NJ, John Wiley & Sons 2010.
Telford JE, Kilbride SM, Davey GP (2010) Decylubiquinone increases mitochondrial function in synaptosomes. J Biol Chem. 285(12):8639-45
McDonald AG, Tipton KF and Davey GP (2009) Mathematical modelling of metabolism. The Biochemist (In Press)
Telford, JE, Kilbride SM and Davey GP. (2009) Complex I is rate limiting for oxygen consumption in the nerve terminal. Journal Biological Chemistry, 284, 9109-9114
Kilbride SM, Telford, JE, Tipton, KF and Davey GP. (2008) Partial inhibition of complex I activity increases Ca2+-independent glutamate release rates from synaptosomes. J. Neurochem 106, 826-834
Upadhyay R and Davey GP (2008) Complex I and energy thresholds in the brain. Biochim Biophys Acta Bioenergetics 1777, 777-782
Kilbride SM, Telford JE, Davey GP (2008) Age-related changes in H2O2 production and bioenergetics in rat brain synaptosomes. Biochim Biophys Acta. Bioenergetics 1777, 783-8
O'Sullivan J, O'Sullivan MI, Tipton KE, Davey G. Inhibition of amine oxidases by the histamine-1 receptor antagonist hydroxyzine. J Neural Transm Suppl. 2006;(71):105-12.
McDonald A, Tipton K, O'Sullivan J, Olivieri A, Davey G, Coonan AM, Fu W. Modelling the roles of MAO and SSAO in glucose transport. J Neural Transm. 2007;114(6):783-6. Epub 2007 Apr 5.
O'Sullivan J, Davey G, O'Sullivan M, Tipton KF. Hydrogen peroxide derived from amine oxidation mediates the interaction between aminosugars and semicarbazide-sensitive amine oxidase. J Neural Transm. 2007;114(6):751-6. Epub 2007 Mar 31.
Palmi M, Davey G, Tipton KF, Meini A. Taurine, taurine analogues, and mitochondrial function and dysfunction. Adv Exp Med Biol. 2006;583:469-79. No abstract available.
Farmer MK, Tipton KF and Davey GP (2004) The effects of two salsolinol derivatives on mitochondrial respiration and the likely nature of any endogenous parkinsonism-inducing toxin. In Monoamine Oxidase inhibitors and their role in neurotransmission (drug development) Medicina Publishing House Co. Budapest (eds Torol and Klebovich) pp 55-78.
Tipton KF, Boyce S, O'Sullivan J., Davey G.P. and Healy J. (2004) Monoamine Oxidases: Certainties and Uncertainties. Current Med. Chemistry 11, 1965-1982
O'Sullivan J, Unzeta M, Healy J, O'Sullivan M, Davey GP and Tipton KF (2003) Semicarbazide-sensitive amine oxidases: enzymes with quite a lot to do. Neurotoxicology 25, 303-315
Tipton K.F., O'Sullivan M., Davey G.P. and O'Sullivan J. (2003) It can be a complicated life being an enzyme. Biochem. Soc. Trans. 31, 711-715
O'Sullivan J., O'Sullivan M., Tipton K.F., Unzeta M., Hernandez M. and Davey G.P. (2003) The inhibition of semicarbazide sensitive sensitive amine oxidase by aminohexoses. Biochem Biophys Acta 1647, 367-371.
Palmi M., Youmbi G., Sgaragli G.P., Meini A., Benocci A., Fusi F., Frosini M., Della Corte L., Davey G. P. and Tipton K.F.(2000) The mitochondrial permeability transition and taurine. Advances in Experimental Medicine and Biology, 483, 87 - 96.
Davey G.P. and Tipton K.F. (2000) Mitochondria, Cell Death and DNA Damage. Radiation Research 2, 390-394.
Tipton K.F., Davey G.P. and Motherway M. (1999) Monoamine oxidase assays. Current Protocols in Pharmacology Vol 2. 3.61-3.6.42.
Davey G.P., Bernahu E. and Tipton K.F. (1999) Inhibition of monoamine oxidase by 7-nitroindazole Journal of Neurochemistry Suppl. 73, S47B.
Davey G.P. and Tipton K.F. (1996) Chronic ethanol consumption and mitochondrial sensitivity to 1-methyl-4-phenylpyridinium ion (MPP+) inhibition Biogenic Amines 12, 103-115
Clark J.B., Davey G.P., Heales S.J.R., Stewart V.C. and Stone R. (1999) Oxidative stress and neurological disease-effects on neurons and astrocytes. Journal of Neurochemistry 74, Suppl. S94D.
Davey G.P., Peuchen S. and Clark J.B. (1998) Energy thresholds in brain mitochondria: potential involvement in neurodegeneration Journal of Biological Chemistry 273, 12753-12757
Davey G.P., Canevari L and Clark J.B. (1997) Threshold effects in synaptosomal and nonsynaptic mitochondria from hippocampal CA1 and paramedian neocortex brain regions Journal of Neurochemistry 69, 2564-2570
Bates T.E., Strangeward Keelan, J., Davey G.P., Munro P.M.G. and Clark J.B. (1996) Inhibition of N-acetylaspartate production: implications for 1H MRS studies in vivo Neuroreport 7, 1397-1400
Davey G.P. and Clark J.B. (1995) Control of oxidative phosphorylation in non-synaptic rat brain mitochondria Journal of Neurochemistry 66, 1617-1624
Almeida A., Brooks K.J., Sammut I., Keelan J., Davey G.P., Clark J.B. and Bates T.E. (1995) The postnatal development of the complexes of the electron transport chain in synaptic mitochondria from rat brain Developmental Neuroscience 17, 212-218
Davey G.P. and Tipton K.F. (1996) Chronic ethanol consumption and mitochondrial sensitivity to 1-methyl-4-phenylpyridinium ion (MPP+) inhibition Biogenic Amines 12, 103-115
Tipton K.F., McBean G.J. and Davey G.P. (1995) Neurotoxins and neurodegenerative diseases Journal of Neurochemistry 65, S65B
Davey G.P. (1994) What causes Parkinson's disease? Technology Ireland 26, 37-39
Davey G.P., Tipton K.F. and Murphy M.P. (1992) Uptake and accumulation of 1-methyl-4-phenylpyridinium by rat liver mitochondria measured using an ion-selective electrode Biochemical Journal 288, 439-443
Davey G.P., Tipton K.F. and Murphy M.P. (1992) Use of an electrode selective for 1-methyl-4-phenylpyridinium (MPP+) to measure its uptake and accumulation by mitochondria Journal of Neural Transmission Suppl. 40, 47-55.