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Professor Martina Hennessy
Assoc Prof Consultant MedicalEducation, Medical Education
Assoc Prof Consultant MedicalEducation, Pharmacology & Therapeutics

Biography

Prof Martina Hennessy is a practicing clinical pharmacologist and consultant physician in St James's Hospital Dublin with expertise in hypertension and cardiovascular risk. In addition, she is Associate Professor in Medical Education in the School of Medicine. Prof Hennessy was the first Fottrell post appointed as part of the HEA curricular reform process in 2007 and was responsible for directing reform of the undergraduate curriculum in medicine. Prof Hennessy is the Director of the Wellcome-HRB Clinical Research Facility in St James's Hospital, Dublin. The CRF is a collaborative partnership between St James's Hospital and Trinity College. Prof Hennessy is also the Director of Internship in The School of Medicine. In January 2023, Prof Hennessy took up the role of Chief Academic Officer (CAO) of the Dublin Midlands hospital Group (DMHG). The DMHG is composed of 7 hospitals, St James's Hospital Dublin, Tallaght University Hospital Dublin, The Coombe Women's Hospital Dublin, St Luke's Radiation Oncology Network at St James's Hospital, Naas General Hospital, Midland Regional Hospital Tullamore and Midland Regional Hospital Portlaoise. The CAO is responsible for developing a structured and integrated approach to research, innovation, education and training for all healthcare professionals in the DMHG. The DMHG which includes its Academic Partner Trinity College Dublin (TCD), is one of the largest of 7 hospital groups established as a key transitional step in a Government initiative to reorganise the Public Health System.

Publications and Further Research Outputs

Peer-Reviewed Publications

Kennedy, Cormac, Hayes, Peter, Salama, Sulafa, Hennessy, Martina, Fogacci, Federica, The Effect of Semaglutide on Blood Pressure in Patients without Diabetes: A Systematic Review and Meta-Analysis, Journal of Clinical Medicine, 12, (3), 2023, p772 Journal Article, 2023 TARA - Full Text DOI

Ó Domhnaill, A. O"Mahony, M., Broderick, B., Hennessy, M., Donnelly, A., Naughton, O., Hurley, E., Carthy, P., Nolan, A., Moriarty, F. and Lyons, S., Impact of Nitrogen Dioxide on Health with Particular Emphasis on Vulnerable Groups, Environmental Protection Agency, 2023, p1 - 48 Report, 2023 URL

Carter M, Tobin A, Coy L, McDonald D, Hennessy M, O'Rourke D, Room to improve: The diagnostic journey of Spinal Muscular Atrophy, European Journal of Paediatric Neurology, 42, 2023, p42 - 46 Journal Article, 2023 URL DOI

Sheill G., Hennessy M., Devenney K., Reynolds S., Towns J., Gill M., Guinan E., A hospital to community exercise referral pathway: results of a pilot project., Irish Journal of Medical Science., 2022 Journal Article, 2022

Kennedy, Cormac, Ali, Osama, Farnan, Richard, Stinson, John, Gabr, Ahmed, Hall, Mary, O"Connor, Patricia, Hennessy, Martina, Barry, Michael, Clinical characteristics of two groups commonly referred to an Irish hypertension service"patients with resistant hypertension and young adults with hypertension, Irish Journal of Medical Science (1971 -), 191, (6), 2022, p2549-2557 Journal Article, 2022 DOI

Cormac Kennedy and Osama Ali and Richard Farnan and John Stinson and Ahmed Gabr and Mary Hall and Patricia O'Connor and Martina Hennessy and Michael Barry, Clinical characteristics of two groups commonly referred to an Irish hypertension service"patients with resistant hypertension and young adults with hypertension, Irish Journal of Medical Science (1971 -), 2022 Journal Article, 2022 TARA - Full Text DOI

McElvaney O.J, McEvoy N.L, Boland F, McElvaney O.F, Hogan G, Donnelly K, Friel O, Browne E, Fraughen D.D, Murphy M.P, Clarke J, Choileáin O.N, O'Connor E, McGuinness R, Boylan M, Kelly A, Hayden J.C, Collins A.M, Cullen A, Hyland D, Carroll T.P, Geoghegan P, Laffey J.G, Hennessy M, Martin-Loeches I, McElvaney N.G, Curley G.F, A randomized, double-blind, placebo-controlled trial of intravenous alpha-1 antitrypsin for ARDS secondary to COVID-19, Med, 3, (4), 2022, p233 - 248.e6 Journal Article, 2022 TARA - Full Text URL DOI

Kamarajah, S.K. and Evans, R.P.T. and Nepogodiev, D. and Hodson, J. and Bundred, J.R. and Gockel, I. and Gossage, J.A. and Isik, A. and Kidane, B. and Mahendran, H.A. and Negoi, I. and Okonta, K.E. and Sayyed, R. and van Hillegersberg, R. and Vohra, R.S. and Wijnhoven, B.P.L. and Singh, P. and Griffiths, E.A. and Kamarajah, S.K. and Hodson, J. and Griffiths, E.A. and Alderson, D. and Bundred, J. and Evans, R.P.T. and Gossage, J. and Griffiths, E.A. and Jefferies, B. and Kamarajah, S.K. and McKay, S. and Mohamed, I. and Nepogodiev, D. and Siaw-Acheampong, K. and Singh, P. and van Hillegersberg, R. and Vohra, R. and Wanigasooriya, K. and Whitehouse, T. and Gjata, A. and Moreno, J.I. and Takeda, F.R. and Kidane, B. and Guevara Castro, R. and Harustiak, T. and Bekele, A. and Kechagias, A. and Gockel, I. and Kennedy, A. and Da Roit, A. and Bagajevas, A. and Azagra, J.S. and Mahendran, H.A. and Mejía-Fernández, L. and Wijnhoven, B.P.L. and El Kafsi, J. and Sayyed, R.H. and Sousa, M. and Sampaio, A.S. and Negoi, I. and Blanco, R. and Wallner, B. and Schneider, P.M. and Hsu, P.K. and Isik, A. and Gananadha, S. and Wills, V. and Devadas, M. and Duong, C. and Talbot, M. and Hii, M.W. and Jacobs, R. and Andreollo, N.A. and Johnston, B. and Darling, G. and Isaza-Restrepo, A. and Rosero, G. and Arias-Amézquita, F. and Raptis, D. and Gaedcke, J. and Reim, D. and Izbicki, J. and Egberts, J.H. and Dikinis, S. and Kjaer, D.W. and Larsen, M.H. and Achiam, M.P. and Saarnio, J. and Theodorou, D. and Liakakos, T. and Korkolis, D.P. and Robb, W.B. and Collins, C. and Murphy, T. and Reynolds, J. and Tonini, V. and Migliore, M. and Bonavina, L. and Valmasoni, M. and Bardini, R. and Weindelmayer, J. and Terashima, M. and White, R.E. and Alghunaim, E. and Elhadi, M. and Leon-Takahashi, A.M. and Medina-Franco, H. and Lau, P.C. and Okonta, K.E. and Heisterkamp, J. and Rosman, C. and van Hillegersberg, R. and Beban, G. and Babor, R. and Gordon, A. and Rossaak, J.I. and Pal, K.M.I. and Qureshi, A.U. and Naqi, S.A. and Syed, A.A. and Barbosa, J. and Vicente, C.S. and Leite, J. and Freire, J. and Casaca, R. and Costa, R.C.T. and Scurtu, R.R. and Mogoanta, S.S. and Bolca, C. and Constantinoiu, S. and Sekhniaidze, D. and BjeloviÄ , M. and So, J.B.Y. and GaÄ evski, G. and Loureiro, C. and Pera, M. and Bianchi, A. and Moreno Gijón, M. and Martín Fernández, J. and Trugeda Carrera, M.S. and Vallve-Bernal, M. and Cítores Pascual, M.A. and Elmahi, S. and Halldestam, I. and Hedberg, J. and Mönig, S. and Gutknecht, S. and Tez, M. and Guner, A. and Tirnaksiz, M.B. and Colak, E. and Sevinç, B. and Hindmarsh, A. and Khan, I. and Khoo, D. and Byrom, R. and Gokhale, J. and Wilkerson, P. and Jain, P. and Chan, D. and Robertson, K. and Iftikhar, S. and Skipworth, R. and Forshaw, M. and Higgs, S. and Gossage, J. and Nijjar, R. and Viswanath, Y.K.S. and Turner, P. and Dexter, S. and Boddy, A. and Allum, W.H. and Oglesby, S. and Cheong, E. and Beardsmore, D. and Vohra, R. and Maynard, N. and Berrisford, R. and Mercer, S. and Puig, S. and Melhado, R. and Kelty, C. and Underwood, T. and Dawas, K. and Lewis, W. and Al-Bahrani, A. and Bryce, G. and Thomas, M. and Arndt, A.T. and Palazzo, F. and Meguid, R.A. and Fergusson, J. and Beenen, E. and Mosse, C. and Salim, J. and Cheah, S., The influence of anastomotic techniques on postoperative anastomotic complications: Results of the Oesophago-Gastric Anastomosis Audit, Journal of Thoracic and Cardiovascular Surgery, 164, (3), 2022, p674-684.e5 Journal Article, 2022 DOI

Michael Patrick O'Shea and Cormac Kennedy and Eileen Relihan and Kieran Harkin and Martina Hennessy and Michael Barry, Assessment of an electronic patient record system on discharge prescribing errors in a Tertiary University Hospital, BMC Medical Informatics and Decision Making, 21, (1), 2021 Journal Article, 2021 TARA - Full Text DOI

McEvoy N.L, Clarke J.L, Mc Elvaney O.J, Mc Elvaney O.F, Boland F, Hyland D, Geoghegan P, Donnelly K, Friel O, Cullen A, Collins A.M, Fraughen D, Martin-Loeches I, Hennessy M, Laffey J.G, Mc Elvaney N.G, Curley G.F, A randomised, double-blind, placebo-controlled, pilot trial of intravenous plasma purified alpha-1 antitrypsin for SARS-CoV-2-induced Acute Respiratory Distress Syndrome: a structured summary of a study protocol for a randomised, controlled trial, Trials, 22, (1), 2021 Journal Article, 2021 TARA - Full Text URL DOI

Kennedy C., Ali O., Farnan R., Hall M., Stinson J., O'Connor P., Hennessy M., Barry M., Is it time to reconsider the treatment paradigm for obese patients with hypertension?, Journal of Human Hypertension, 2021 Journal Article, 2021 DOI TARA - Full Text

Cormac Kennedy and Richard Farnan and John Stinson and Mary Hall and Linda Hemeryck and Patricia O'Connor and Martina Hennessy and Michael Barry, Referrals to, and characteristics of patients attending a specialist hypertension clinic, Journal of Human Hypertension, 2021 Journal Article, 2021 TARA - Full Text

Ridge K, Conlon N, Hennessy M, Dunne P.J, Correction to: Feasibility assessment of an 8-week attention-based training programme in the management of chronic spontaneous urticarial (Pilot and Feasibility Studies, (2021), 7, 1, (103), 10.1186/s40814-021-00841-z), Pilot and Feasibility Studies, 7, (1), 2021 Journal Article, 2021 TARA - Full Text URL DOI

Hennus, Marije P., Young, John Q., Hennessy, Martina, Friedman, Karen A., de Vries, Bas, Hoff, Reinier G., O"Connor, Enda, Patterson, Aileen, Curley, Gerard, Thakker, Krima, van Dam, Marjel, van Dijk, Diederik, van Klei, Wilton A., ten Cate, Olle, Supervision, Interprofessional Collaboration, and Patient Safety in Intensive Care Units during the COVID-19 Pandemic, ATS Scholar, 2021, pats-scholar.202 Journal Article, 2021 DOI TARA - Full Text

Sheill G., Hennessy M., O'Neill L., Reynolds S., Towns J., Gill M., Guinan E., Exercise and chronic health conditions in the community: A qualitative Study of Patients and Fitness instructors, Health and Social Care in the Community, 2021 Journal Article, 2021 DOI

Kamarajah, S.K. and Nepogodiev, D. and Bekele, A. and Cecconello, I. and Evans, R.P.T. and Guner, A. and Gossage, J.A. and Harustiak, T. and Hodson, J. and Isik, A. and Kidane, B. and Leon-Takahashi, A.M. and Mahendran, H.A. and Negoi, I. and Okonta, K.E. and Rosero, G. and Sayyed, R.H. and Singh, P. and Takeda, F.R. and van Hillegersberg, R. and Vohra, R.S. and White, R.E. and Griffiths, E.A. and Alderson, D. and Bundred, J. and Gossage, J. and Jefferies, B. and McKay, S. and Mohamed, I. and Siaw- Acheampong, K. and Vohra, R. and Wanigasooriya, K. and Whitehouse, T. and Gjata, A. and Moreno, J.I. and Guevara, C.R. and Kechagias, A. and Gockel, I. and Kennedy, A. and Da Roit, A. and Bagajevas, A. and Azagra, J.S. and Mejía-Fernández, L. and Wijnhoven, B.P.L. and El Kafsi, J. and Sousa, M. and Sampaio, A.S. and Blanco, R. and Wallner, B. and Schneider, P.M. and Hsu, P.K. and Gananadha, S. and Wills, V. and Devadas, M. and Duong, C. and Talbot, M. and Hii, M.W. and Jacobs, R. and Andreollo, N.A. and Johnston, B. and Darling, G. and Isaza-Restrepo, A. and Arias- Amézquita, F. and Raptis, D. and Gaedcke, J. and Reim, D. and Izbicki, J. and Egberts, J.H. and Dikinis, S. and Kjaer, D.W. and Larsen, M.H. and Achiam, M.P. and Saarnio, J. and Theodorou, D. and Liakakos, T. and Korkolis, D.P. and Robb, W.B. and Collins, C. and Murphy, T. and Reynolds, J. and Tonini, V. and Migliore, M. and Bonavina, L. and Valmasoni, M. and Bardini, R. and Weindelmayer, J. and Terashima, M. and Alghunaim, E. and Elhadi, M. and Medina-Franco, H. and Lau, P.C. and Heisterkamp, J. and Rosman, C. and Beban, G. and Babor, R. and Gordon, A. and Rossaak, J.I. and Pal, K.M.I. and Qureshi, A.U. and Naqi, S.A. and Syed, A.A. and Barbosa, J. and Vicente, C.S. and Leite, J. and Freire, J. and Casaca, R. and Costa, R.C.T. and Scurtu, R.R. and Mogoanta, S.S. and Bolca, C. and Constantinoiu, S. and Sekhniaidze, D. and BjeloviÄ , M. and So, J.B.Y. and GaÄ evski, G. and Loureiro, C. and Pera, M. and Bianchi, A. and Moreno, G.M. and Martín Fernández, J. and Trugeda Carrera, M.S. and Vallve-Bernal, M. and Cítores Pascual, M.A. and Elmahi, S. and Halldestam, I. and Hedberg, J. and Mönig, S. and Gutknecht, S. and Tez, M. and Tirnaksiz, M.B. and Colak, E. and Sevinç, B. and Hindmarsh, A. and Khan, I. and Khoo, D. and Byrom, R. and Gokhale, J. and Wilkerson, P. and Jain, P. and Chan, D. and Robertson, K. and Iftikhar, S. and Skipworth, R. and Forshaw, M. and Higgs, S. and Nijjar, R. and Viswanath, Y.K.S. and Turner, P. and Dexter, S. and Boddy, A. and Allum, W.H. and Oglesby, S. and Cheong, E. and Beardsmore, D. and Maynard, N. and Berrisford, R. and Mercer, S. and Puig, S. and Melhado, R. and Kelty, C. and Underwood, T. and Dawas, K. and Lewis, W. and Al-Bahrani, A. and Bryce, G. and Thomas, M. and Arndt, A.T. and Palazzo, F. and Meguid, R.A. and Fergusson, J. and Beenen, E. and Mosse, C. and Salim, J. and Cheah, S. and Wright, T. and Cerdeira, M.P. and McQuillan, P. and Richardson, M. and Liem, H. and Spillane, J. and Yacob, M. and Albadawi, F. and Thorpe, T. and Dingle, A. and Cabalag, C. and Loi, K. and Fisher, O.M. and Ward, S. and Read, M. and Johnson, M. and Bassari, R. and Bui, H. and Sallum, R.A.A. and da Rocha, J.R.M. and Lopes, L.R. and Tercioti, V. and Coelho, J.D. and Ferrer, J.A.P., Mortality from esophagectomy for esophageal cancer across low, middle, and high-income countries: An international cohort study, European Journal of Surgical Oncology, 2021 Journal Article, 2021 TARA - Full Text DOI

Burke, E., HEennessy, M, Evaluation of an early career clinical academic training programme using the CIPP model, BMJ Open , 11, (11), 2021 Journal Article, 2021 DOI URL

O'Shea M, Kennedy C, Relihan E, Harkin K, Hennessy M, Barry M, Assessment of an Electronic Patient Record System on Discharge Prescribing Errors in a Tertiary University Hospital, 2021 Journal Article, 2021 DOI

Kennedy C., O'Dea E., Reidy D., Towns J., Pigott M., Kevans D., O'Rourke D., Hennessy M., Challenging times: Delivering gene therapies and an opportunity for shared learning, British Journal of Clinical Pharmacology, 2021 Journal Article, 2021 TARA - Full Text DOI

Philip Carthy, Aonghus Ó Domhnaill, Margaret O'Mahony, Anne Nolan, Frank Moriarty, Brian Broderick, Martina Hennessy, Aoife Donnelly, Owen Naughton, Sean Lyons, Local NO2 concentrations and asthma among over-50s in Ireland: A microdata analysis, International Journal of Epidemiology, 49, (6), 2020, p1899 - 1908 Journal Article, 2020 URL TARA - Full Text

Carthy, P., O'Domhnaill, A., O'Mahony. M., Broderick, B.M., Hennessy, M., Donnelly, A., Naughton, O. and Lyons, S, Local NO2 concentrations and asthma among over-50s in Ireland: a microdata analysis, International Journal of Epidemiology , 49, (6), 2020, p1899 - 1908 Journal Article, 2020 TARA - Full Text DOI

Delaney H., Devane D., Hennessy M., Parker A., Murphy L., Cronin P., Smith V. , Limited evidence exists on the effectiveness of education and training interventions on trial recruitment; a systematic review, Journal of Clinical Epidemiology, 113, 2019, p75 - 82 Journal Article, 2019 DOI TARA - Full Text

O"Shea MP, Harkin K, Sulaiman HM, Hennessy M, Barry M, Kennedy C., More Teaching Not More Exams: Interns Views in Improving Prescribing Safety, Irish medical journal, 112, (5), 2019, p943 Journal Article, 2019 DOI TARA - Full Text

Burke E, Teeling M, Hennessy M, Introduction of an academic Internship in Ireland: views of undergraduate medical students, Irish Journal of Medical Science, 2018 Journal Article, 2018 DOI

, Push and stay factors affecting Irish medical student migration intentions., Irish journal of medical science, 2017 Journal Article, 2017 TARA - Full Text

Orikiiriza J, Nakawesi J, Kikaire B, Turitwenka D, Schlech W, Kambugu A, Lamorde M, Normark J, Hennessy M, Musiime V, Rujumba J, Ndeezi G, Tumwesigye NM, Doherty DG, Achan J, Unmet needs persist in pediatric HIV programs: lessons from selected case studies in Uganda. , AIDS , 31, 2017, p1196 - 1199 Journal Article, 2017 DOI TARA - Full Text

Patterson, M., Sharek, D., Hennessy, M., Phillips, M., and Schofield S., Medical humanities: A closer look at learning, Medical Humanities, 42, (2), 2016, p115 - 120 Journal Article, 2016

Gouda, P., Kitt, K., Evans, D.S., Goggin, D., McGrath, D., Last, J., Hennessy, M., Arnett, R., O"Flynn, S., Dunne, F., O"Donovan, D., Irish medical students" understanding of the intern year, Irish Medical Journal, 109, (4), 2016 Journal Article, 2016

R Woods, T Subramaniam, A Patterson, M Hennessy, C Timon, Validation and evaluation of new assessments for the otolaryngology undergraduate medical clerkship., The Journal of Laryngology and Otology, 2015, p1 - 6 Journal Article, 2015 URL

Morris MC, Hennessy M, Conlon KC, Ridgway PF., Evaluation of a "Subintern" Role: Action Over Observation For Final-Year Medical Students in Surgery., J Surg Educ, 72, (5), 2015, p862 - 867 Journal Article, 2015 DOI

Donohoe C.L, Conneely J.B, Zilbert N, Hennessy M, Schofield S, Reynolds J.V, Docemur Docemus: Peer-Assisted Learning Improves the Knowledge Gain of Tutors in the Highest Quartile of Achievement but Not Those in the Lowest Quartile, Journal of Surgical Education, 72, (6), 2015, p1139 - 1144 Journal Article, 2015 DOI URL

, Investigating the Irish brain drain: factors influencing migration intentions among medical students., BMC proceedings, 2015 Journal Article, 2015

Gouda, P., Kitt, K., Evans, D.S., Goggin, D., McGrath, D., Last, J., Hennessy, M., Arnett, R., O'Flynn, S., Dunne, F., O'Donovan, D., Ireland's medical brain drain: Migration intentions of Irish medical students, Human Resources for Health, 13, (1), 2015 Journal Article, 2015

Kennedy A, Petrasca A, Doherty DG, Hennessy M, Spiers JP, HIV-1 Tat clade-specific cytokine induction in monocytes/macrophages is not evidenced in total or V"9V"2 T lymphocytes., AIDS (London, England), 28, (1), 2014, p131-3 Journal Article, 2014 URL

Laragh Stevens, Maureen Kelly, Martina Hennessy, Jason Last, Fidelma Dunne, Siun O'Flynn , Medical Student Views on Selection Tools for Medicine- A mixed methods study. Accepted by Irish Medical Journal , Irish medical Journal , 2014, p229 - 231 Journal Article, 2014

Stevens, L., Kelly, M.E., Hennessy, M., Last, J., Dunne, F., O"Flynn, S., Medical students views on selection tools for medical school " A mixed methods study, Irish Medical Journal, 107, (8), 2014 Journal Article, 2014

Svärd J, Blanco F, Nevin D, Fayne D, Mulcahy F, Hennessy M, Spiers JP, Differential interactions of antiretroviral agents with LXR, ER and GR nuclear receptors: potential contributing factors to adverse events., British journal of pharmacology, 171, (2), 2014, p480-97 Journal Article, 2014

Hennessy , Quinn, Annual Report: Development Studies Association of Ireland , Trinity College Dublin , 2014 Report, 2014

Morris, M.C., Gillis, A.E., Smoothey, C.O., Hennessy, M., Conlon, K.C., Ridgway, P.F., An alternative certification examination ("ACE") in surgery, Journal of Surgical Education, 71, (6), 2014, p779-789 Journal Article, 2014

Alan Kennedy, HIV-1 Tat clade-specific cytokine induction in monocytes/macrophages is not evidenced in total or Vγ9Vδ2 T lymphocytes, AIDS, 28(1):131-3, (1), 2014, p131 - 133 Journal Article, 2014 URL

Morris MC, Gillis AE, Smoothey CO, Hennessy M, Conlon KC, Ridgway PF, An Alternative Certification Examination ("ACE") in Surgery., Journal of surgical education, 2014, p779-789 Journal Article, 2014 TARA - Full Text DOI

Kennedy, A. Doherty , D.G Petrasca, A. Hennessy, M. Spiers, J.P., HIV-1 Tat clade-specific cytokine induction in monocytes/macrophages is not evidenced in total or Vγ9Vδ2 T lymphocytes, AIDS, 28, 2014, p131 - 133 Journal Article, 2014 DOI

, Medical students' views on selection tools for medical school--a mixed methods study., Irish medical journal, 2014 Journal Article, 2014

Woods R, Ramasubbu B, Donohoe C, Hennessy M, Near-peer bedside clinical teaching: example of a successful programme., The clinical teacher, 11, (6), 2014, p472-7 Journal Article, 2014

Morris M, Donohoe G, Hennessy M, O Ciardha C, Pro forma: impact on communication skills?, The clinical teacher, 10, (5), 2013, p318-22 Journal Article, 2013

O' Flynn S, Power Susan, Hennessy M, Mills A, Lapthorne S. , 'Guidance Counsellors perspectives on revised entry and selection mechanisms to medicine and the HPAT', Institute of Guidance Counsellors, 2013, - 7-10 Protocol or guideline, 2013

HPAT Research group , National research group evaluating revised entry mechanisms to medicine, IUA/ CDFMSI, 2013, 24 pp Report, 2013

M Phillips, M Hennessy, A Patterson, Power and its Applications: a new module in the medical curriculum at Trinity College Dublin, Medical Humanities, 2013 Journal Article, 2013

, Pro forma: impact on communication skills?, The clinical teacher, 2013 Journal Article, 2013

Rietz, A. Volkov, Y. Davies, A. Hennessy, M. Spiers, J., Okadaic acid induces MMP-9 expression in fibroblast: Crosstalk between protein phosphatase inhibition and β-adrenoceptor signalling, British Journal of Pharmacology, 165, 2012, p274 - 288 Journal Article, 2012

Rietz, A., Volkov, Y., Davies, A., Hennessy, M., Spiers, J.P., Okadaic acid induces matrix metalloproteinase-9 expression in fibroblasts: Crosstalk between protein phosphatase inhibition and ß-adrenoceptor signalling, British Journal of Pharmacology, 165, (1), 2012, p274-288 Journal Article, 2012

Abulhul E, McDonald K, Martos R, Phelan D, Spiers JP, Hennessy M, Baugh J, Watson C, O'Loughlin C, Ledwidge M, Long-Term Statin Therapy in Patients With Systolic Heart Failure and Normal Cholesterol: Effects on Elevated Serum Markers of Collagen Turnover, Inflammation, and B-Type Natriuretic Peptide., Clinical Therapeutics, 34, (1), 2012, p91 - 100 Journal Article, 2012

Kennedy A, Hennessy M, Bergin C, Mulcahy F, Hopkins S, Spiers JP, Ribavirin and interferon alter MMP-9 abundance in vitro and in HIV-HCV-coinfected patients., Antiviral therapy, 16, (8), 2011, p1237-47 Journal Article, 2011

Phillips M, Pilkington R, Patterson A, Hennessy M, Death and dignity through fresh eyes., The clinical teacher, 8, (4), 2011, p241-244 Journal Article, 2011 DOI

Svärd J, Spiers JP, Mulcahy F, Hennessy M, Nuclear receptor-mediated induction of CYP450 by antiretrovirals: functional consequences of NR1I2 (PXR) polymorphisms and differential prevalence in whites and sub-Saharan Africans., Journal of acquired immune deficiency syndromes (1999), 55, (5), 2010, p536-49 Journal Article, 2010

McMahon CJ, Hennessy M, Boyle G, Feely J, Meaney JF, Prevalence of renal artery stenosis in flash pulmonary oedema: determination using gadolinium-enhanced MRA., European journal of internal medicine, 21, (5), 2010, p424-8 Journal Article, 2010

Molloy D, Molloy A, O'Loughlin C, Falconer M, Hennessy M, Inappropriate use of proton pump inhibitors., Irish journal of medical science, 179, (1), 2010, p73-5 Journal Article, 2010

Hennessy, M.; Spiers, J.P., A primer on the mechanics of P-glycoprotein the multi drug transporter, Pharmacological Research, 55, 2007, p1 - 15 Journal Article, 2007

Song,G.; Hennessy,M.; Zhao,Y.L.; Li,Q.; Han,W.D.; Qi,Y.; Zhao,W.N.; Silke,B.; Barry,M.; Doyle,R.; Spiers,J.P., Adrenoceptor blockade alters plasma gelatinase activity in patients with heart failure and MMP-9 promoter activity in a human cell line (ECV304), Pharmacological Research, 54, 2006, p57 - 64 Journal Article, 2006

Hopkins S, Lambourne J, Farrell G, McCullagh L, Hennessy M, Clarke S, Mulcahy F, Bergin C, Role of individualization of hepatitis C virus (HCV) therapy duration in HIV/HCV-coinfected individuals., HIV medicine, 7, (4), 2006, p248-54 Journal Article, 2006

Hopkins S, Lambourne J, Farrell G, McCullagh L, Hennessy M, Clarke S, Mulcahy F, Bergin C., Role of individualization of hepatitis C virus (HCV) therapy duration in HIV/HCV-coinfected individuals., HIV Med. , 7, (4), 2006, p248-54. Journal Article, 2006 DOI URL

Spiers,J.P.; Kelso,E.J.; Fong,S.; Edge,G.; Song,G.; McDermott,B.J.; Hennessy,M., Alterations in vascular matrix metalloproteinase due to ageing and chronic hypertension: effects of endothelin receptor blockade, Journal of Hypertension, 23, 2005, p1717 - 1724 Journal Article, 2005

Hennessy,M.; Clarke,S.; Spiers,J.P.; Kelleher,D.; Mulcahy,F.; Hoggard,P.; Back,D.; Barry,M., Intracellular accumulation of nelfinavir and its relationship to P-glycoprotein expression and function in HIV infected patients, Antiviral Therapy, 9, 2004, p115 - 122 Journal Article, 2004

Hennessy M, Clarke S, Spiers JP, Kelleher D, Mulcahy F, Hoggard P, Back D, Barry M, Intracellular accumulation of nelfinavir and its relationship to P-glycoprotein expression and function in HIV-infected patients., Antiviral therapy, 9, (1), 2004, p115-22 Journal Article, 2004

Hennessy M, Clarke S, Spiers JP, Mulcahy F, Kelleher D, Meadon E, Maher B, Bergin C, Khoo S, Tjia J, Hoggard P, Back D, Barry M, Intracellular indinavir pharmacokinetics in HIV-infected patients: comparison with plasma pharmacokinetics., Antiviral therapy, 8, (3), 2003, p191-8 Journal Article, 2003

Hennessy,M.; Clarke,S.; Spiers,J.P.; Mulcahy,F.; Kelleher,D.; Meadon,E.; Maher,B.; Bergin,C.; Tjia,J.; Hoggard,P.; Back,D.; Barry,M., Intracellular indinavir pharmacokinetics in HIV infected patients: comparison with plasma pharmacokinetics, Antiviral Therapy, 8, 2003, p191 - 198 Journal Article, 2003

M. Hennessy, S. Clarke, J. P. Spiers, F. Mulcahy, D. Kelleher, E. Meadon, B. Maher, C. Bergin, S. Khoo, J. Tjia, P. Hoggard, D. Back and M. Barry, Intracellular indinavir pharmacokinetics in HIV-infected patients: comparison with plasma pharmacokinetics, Antiviral therapy, 8, (3), 2003, p191-8 Journal Article, 2003 URL

Hennessy M., Clarke S., Spiers J.P., Kelleher D., Mulcahy F., Hoggard P., Back D., Barry M., Intracellular accumulation of Nelfinavir and its relationship to P-glycoprotein Expression and function in HIV infected patients, Antivir Ther., 8, (3), 2003, p191 - 198 Journal Article, 2003

M. Hennessy, D. Kelleher, J. P. Spiers, M. Barry, P. Kavanagh, D. Back, F. Mulcahy and J. Feely, St Johns wort increases expression of P-glycoprotein: implications for drug interactions, British Journal of Clinical Pharmacology, 53, (1), 2002, p75-82 Journal Article, 2002 TARA - Full Text DOI URL

Mahmud A, Hennessy M, Feely J, Effect of sildenafil on blood pressure and arterial wave reflection in treated hypertensive men., Journal of human hypertension, 15, (10), 2001, p707-13 Journal Article, 2001

A. Mahmud, M. Hennessy and J. Feely, Effect of sildenafil on blood pressure and arterial wave reflection in treated hypertensive men, Journal of Human Hypertension, 15, (10), 2001, p707-13 Journal Article, 2001 URL

A.Mahmud, M. Hennessy, J. Feely, Effect of sildenafil on blood pressure and arterial wave reflection in treated hypertensive men, Journal of Human Hypertension, 15, 2001, p707 - 713 Journal Article, 2001

Hennessy M, Merry C, Mahmud A, Ryan M, Feely J, Interaction Of Sildenafil And Indinavir When Co-Administered To HIV Positive Patients, European Association Of Clinical Pharmacology And Therapeutics, Jerusalem, 1999 Poster, 1999

Hennessy M, Barry M, Drug interactions of clinical significance. , Irish Medical Times , 1999 Journal Article, 1999

Merry C, Barry MG, Ryan M, Tjia JF, Hennessy M, Eagling VA, Mulcahy F, Back DJ, Interaction of sildenafil and indinavir when co-administered to HIV-positive patients., AIDS (London, England), 13, (15), 1999, pF101-7 Journal Article, 1999

Hennessy M, Feely J. , Understanding Drug Interactions. , Modern Medicine in Ireland , 1998 Journal Article, 1998

Non-Peer-Reviewed Publications

Martina Hennessy, Dawn Quinn , TIDI Impact report , Trinity College Dublin , July , 2014 Report, 2014

Martina Hennessy, Dawn Quinn, TIDI Impact Report , Trinity College Dublin , July , 2013 Report, 2013

Uduma, Hennessy , A Report on North South Experiences of Doctoral Training for Development in Africa, Trinity College dublin , November , 2012 Report, 2012 TARA - Full Text

Uduma, Hennessy , Building Research Capacity in Higher Education Institutes through Partnerships with African Universities, Trinity College Dublin , November , 2012 Report, 2012

Feely J, Hennessy M, Sheehan O, 'Hypertension and Health a Patient Guide. ', Dept of Clinical Pharmacology and therapeutics , 2000, - Protocol or guideline, 2000

Research Expertise

Projects

  • Title
    • NOURISH :development of an irish-Ugandan HIV/ Nutrition research cluster Irish Aid / HEA
  • Funding Agency
    • Irish Aid / Hea
  • Date From
    • 2012
  • Date To
    • 2016
  • Title
    • Doctoral training for Development in Africa
  • Funding Agency
    • irish Aid/ HEA
  • Date From
    • 2008
  • Date To
    • 2014
  • Title
    • Establishment of a Dublin HIV Cohort Database
  • Funding Agency
    • HRB
  • Date From
    • 2005
  • Date To
    • 2010
  • Title
    • Role of the nuclear receptors (PXR and CAR) and thymidine kinase polymorphisms on the pharmacodynamics and pharmacokinetics of antiretroviral therapy in HIV disease
  • Summary
  • Funding Agency
    • European Clinical Aids Society
  • Date From
    • 2006
  • Date To
    • 2010
  • Title
    • Proposal to Expand and consolidate the Development Studies Association of Ireland in collaboration with TIDI
  • Funding Agency
    • Irish Aid
  • Date From
    • 2012
  • Date To
    • 2016
  • Title
    • Medicine 2 Research - Led teaching in Medicine
  • Summary
    • Thematic priority Research Led Teaching
  • Funding Agency
    • MEDINE 2 Network for Medical Education in Europe
  • Date From
    • 2009
  • Date To
    • 2012
  • Title
    • Development of an e-repository of integrative case studies
  • Summary
  • Funding Agency
    • Trinity College Dublin
  • Date From
    • 2008
  • Date To
    • 2010
  • Title
    • Curricular Reform of Medical Education in ireland
  • Summary
    • Non Peer Reviewed HEA funding for curricular reform and development of Academic Clinician Posts
  • Funding Agency
    • HEA
  • Date From
    • 2007
  • Date To
    • 2014
  • Title
    • Proposal for the establishment of a Medication Safety Team for St James's Hospital, Dublin
  • Summary
  • Funding Agency
    • HSE
  • Date From
    • 2003
  • Date To
    • Ongoing
  • Title
    • Development of interactive web based Continual assessment for pharmacology
  • Funding Agency
    • Trinity College
  • Date From
    • 2005
  • Date To
    • 2007
  • Title
    • Effect of ß-Adrenoceptor Antagonism on Plasma Matrix Metalloproteinase Activity and Oxidative State in Stable Heart Failure.
  • Funding Agency
    • Baggot Street Fund
  • Date From
    • 2001
  • Date To
    • 2004
  • Title
    • Nourish extension project
  • Summary
    • to build on previous nourish work b supporting the PhD students in the early post doctoral phase
  • Funding Agency
    • HEA/ Irish AID
  • Date From
    • 2018
  • Date To
    • 2020

Recognition

Representations

Member,Education sub-committee Medical Council representing University 2009- present

Chair,Medication safety committee St James's Hospital 2011-present

Member. Patient Safety committee Tallaght Hospital 2013-present

Member Board of Governance of Clinical Research Facility ST James's Hospital 2013-present

Member European Academic alliance in Global Health 2010- present

Internship oversight committee - representing the Trinity Network of Interns (123) 2011 - present

member of Eurolife International health committee representing university 2008-present

HEA Clinical Skills development advisory group 2008-2009

Irish University Medical School Consortium 2011- present

Awards and Honours

UCL Teaching Award, Royal Free and University College Medical School Academic 2006

Glaxo-Wellcome CPS Oral Communications Prize British Pharmacological Society, 2001. The role of the multi-drug transporter P-glycoprotein in HIV disease 2001

Bristol Myers Squibb Travel Scholarship Award British HIV Association, April 2001 The Clinical Implications of P-glycoprotein Expression and Function in HIV Positive Patients. 2001

Royal Academy of Medicine in Ireland Registrars prize (2nd) April 2001 The Role of P-glycoprotein Expression and Function in HIV Positive Patients. 2001

Glaxo-Wellcome Oral communications Prize British Pharmacological Society, Jan 2000 The Pharmacokinetics of Nelfinavir Administered Twice Versus Three Times Daily in HIV positive Patients. 2000

The Irish Association of Pharmacologists Oral communications prize, Nov 2000 A Role for P glycoprotein Expression and Function in Drug Interactions with St John's Wort. 2000

Society for Sexually Transmitted Diseases in Ireland Oral communications Prize April 2000. The Clinical Implications of Intracellular Protease Inhibitor Concentrations in HIV Patients. 2000

Professors prize in Paediatrics 1994

1st honours Medical Jurisprudence 5th medical year. 1993

Overall honours 2nd and 3rd medical years combined 1992

Distinction in Pharmacology 3rd medical year. 1992

Memberships

Fellow Royal college of Physicians in Ireland 2006 – present

Fellow Royal college of Physicians London 2007 – present

British Hypertension society initially as a student 2000 – present

British Pharmacological Society 1998 – present

Eurolife Network of Universities 2008 – present

Development Studies Association of Ireland 2012 – present

London Clinical Pharmacology group 2004 – 2010

British HIV Association 2003 – 2008