Immune Sensing and Signalling
Professor Andrew Bowie
Professor of Innate Immunology
Andrew Bowie is Professor of Innate Immunology in the School of Biochemistry and Immunology. He obtained his PhD in Biochemistry from TCD in 1997, was elected a Fellow of TCD in 2008, and a member of the Royal Irish Academy in 2014. His research expertise is in the area of innate immunity, and work in his laboratory has shed light on how the innate immune system detects pathogens, how pathogens evade and subvert such detection, and also how innate immunity contributes to harmful inflammation.
Our research focuses on innate immune sensing and signalling mechanisms, and their modulation by viruses. We are examining how viruses and other pathogens are initially detected by the innate immune system, leading to the activation of transcription factors and altered gene expression.