Professor Martin Caffrey
Fellow Emeritus, Biochemistry
Fellow Emeritus, Clinical Medicine
Fellow Emeritus, School Office - Medicine
Publications and Further Research Outputs
Peer-Reviewed Publications
El Ghachi, M. and Howe, N. and Huang, C.-Y. and Olieric, V. and Warshamanage, R. and Touzé, T. and Weichert, D. and Stansfeld, P.J. and Wang, M. and Kerff, F. and Caffrey, M., Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis, Nature Communications, 9, (1), 2018
Yin, W. and Zhou, X.E. and Yang, D. and De Waal, P.W. and Wang, M. and Dai, A. and Cai, X. and Huang, C.-Y. and Liu, P. and Wang, X. and Yin, Y. and Liu, B. and Zhou, Y. and Wang, J. and Liu, H. and Caffrey, M. and Melcher, K. and Xu, Y. and Wang, M.-W. and Xu, H.E. and Jiang, Y., Crystal structure of the human 5-HT
Boland C, Olatunji S, Bailey J, Howe N, Weichert D, Fetics S.K, Yu X, Merino-Gracia J, Delsaut C, Caffrey M, Membrane (and Soluble) Protein Stability and Binding Measurements in the Lipid Cubic Phase Using Label-Free Differential Scanning Fluorimetry, Analytical Chemistry, 90, (20), 2018, p12152 - 12160
Wiktor, M. and Caffrey, M., Biophysical characterization and stabilization of detergent-solubilized lipoprotein N-acyl transferase from P. aeruginosa and E. coli, Biochimica et Biophysica Acta - Biomembranes, 1860, (6), 2018, p1384-1393
Parker, J.L. and Li, C. and Brinth, A. and Wang, Z. and Vogeley, L. and Solcan, N. and Ledderboge-Vucinic, G. and Swanson, J.M.J. and Caffrey, M. and Voth, G.A. and Newstead, S., Proton movement and coupling in the POT family of peptide transporters, Proceedings of the National Academy of Sciences of the United States of America, 114, (50), 2017, p13182-13187
Wiktor, M. and Weichert, D. and Howe, N. and Huang, C.-Y. and Olieric, V. and Boland, C. and Bailey, J. and Vogeley, L. and Stansfeld, P.J. and Buddelmeijer, N. and Wang, M. and Caffrey, M., Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis, Nature Communications, 8, 2017, p15952-
Ma, P. and Weichert, D. and Aleksandrov, L.A. and Jensen, T.J. and Riordan, J.R. and Liu, X. and Kobilka, B.K. and Caffrey, M., The cubicon method for concentrating membrane proteins in the cubic mesophase, Nature Protocols, 12, (9), 2017, p1745-1762
Ghachi M.E, Howe N, Auger R, Lambion A, Guiseppi A, Delbrassine F, Manat G, Roure S, Peslier S, Sauvage E, Vogeley L, Rengifo-Gonzalez J.-C, Charlier P, Mengin-Lecreulx D, Foglino M, Touzé T, Caffrey M, Kerff F, Crystal structure and biochemical characterization of the transmembrane PAP2 type phosphatidylglycerol phosphate phosphatase from Bacillus subtilis, Cellular and Molecular Life Sciences, 74, (12), 2017, p2319-2332
Caffrey, M. and Drew, D., Editorial overview: Membranes, Current Opinion in Structural Biology, 45, 2017, pvii-ix
Huang C.Y, Olieric V, Ma P, Howe N, Vogeley L, Liu X, Warshamanage R, Weinert T, Panepucci E, Kobilka B, Diederichs K, Wang M, Caffrey M, In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures, Acta crystallographica. Section D, Structural biology, 72, 2016, p93 - 112
Wojdyla J.A, Panepucci E, Martiel I, Ebner S, Huang C.-Y, Caffrey M, Bunk O, Wang M, Fast two-dimensional grid and transmission X-ray microscopy scanning methods for visualizing and characterizing protein crystals, Journal of Applied Crystallography, 49, 2016, p944 - 952
Rues R.-B, Henrich E, Boland C, Caffrey M, Bernhard F, Cell-free production of membrane proteins in escherichia coli lysates for functional and structural studies, Protocol Heterologous Expression of Membrane Proteins, 1432, 2016, p1-21
Vogeley L, El Arnaout T, Bailey J, Stansfeld P.J, Boland C, Caffrey M, Structural basis of lipoprotein signal peptidase II action and inhibition by the antibiotic globomycin, Science, 351, (6275), 2016, p876 - 880
Zhou X.E, Gao X, Barty A, Kang Y, He Y, Liu W, Ishchenko A, White T.A, Yefanov O, Han G.W, Xu Q, De Waal P.W, Suino-Powell K.M, Boutet S, Williams G.J, Wang M, Li D, Caffrey M, Chapman H.N, Spence J.C.H, Fromme P, Weierstall U, Stevens R.C, Cherezov V, Melcher K, Xu H.E, X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex, Scientific Data, 3, 2016, p21-
Olieric V, Weinert T, Finke A.D, Anders C, Li D, Olieric N, Borca C.N, Steinmetz M.O, Caffrey M, Jinek M, Wang M, Data-collection strategy for challenging native SAD phasing, Acta Crystallographica Section D: Structural Biology, 72, (3), 2016, p421 - 429
Huang C.-Y, Olieric V, Ma P, Panepucci E, Diederichs K, Wang M, Caffrey M, In meso in situ serial X-ray crystallography of soluble and membrane proteins, Acta Crystallographica Section D: Biological Crystallography, 71, 2015, p1238 - 1256
Li D, Stansfeld P.J, Sansom M.S.P, Keogh A, Vogeley L, Howe N, Lyons J.A, Aragao D, Fromme P, Fromme R, Basu S, Grotjohann I, Kupitz C, Rendek K, Weierstall U, Zatsepin N.A, Cherezov V, Liu W, Bandaru S, English N.J, Gati C, Barty A, Yefanov O, Chapman H.N, Diederichs K, Messerschmidt M, Boutet S, Williams G.J, Seibert M.M, Caffrey M, Ternary structure reveals mechanism of a membrane diacylglycerol kinase, Nature Communications, 6, 2015, p10140-
Li, D. Pye, V.E. Caffrey, M., Experimental phasing for structure determination using membrane-protein crystals grown by the lipid cubic phase method, Acta Crystallographica Section D Biological Crystallography, 71, 2015, p104 - 122
Fowler P.W, Orwick-Rydmark M, Radestock S, Solcan N, Dijkman P.M, Lyons J.A, Kwok J, Caffrey M, Watts A, Forrest L.R, Newstead S, Gating topology of the proton-coupled oligopeptide symporters, Structure, 23, (2), 2015, p290 - 301
Kang Y, Zhou X.E, Gao X, He Y, Liu W, Ishchenko A, Barty A, White T.A, Yefanov O, Han G.W, Xu Q, De Waal P.W, Ke J, Tan M.H.E, Zhang C, Moeller A, West G.M, Pascal B.D, Van Eps N, Caro L.N, Vishnivetskiy S.A, Lee R.J, Suino-Powell K.M, Gu X, Pal K, Ma J, Zhi X, Boutet S, Williams G.J, Messerschmidt M, Gati C, Zatsepin N.A, Wang D, James D, Basu S, Roy-Chowdhury S, Conrad C.E, Coe J, Liu H, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan M, Yang H, Li J, Wang M, Zheng Z, Li D, Howe N, Zhao Y, Standfuss J, Diederichs K, Dong Y, Potter C.S, Carragher B, Caffrey M, Jiang H, Chapman H.N, Spence J.C.H, Fromme P, Weierstall U, Ernst O.P, Katritch V, Gurevich V.V, Griffin P.R, Hubbell W.L, Stevens R.C, Cherezov V, Melcher K, Xu H.E, Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser, Nature, 523, (7562), 2015, p561 - 567
Stansfeld P.J, Goose J.E, Caffrey M, Carpenter E.P, Parker J.L, Newstead S, Sansom M.S.P, MemProtMD: Automated Insertion of Membrane Protein Structures into Explicit Lipid Membranes, Structure, 23, (7), 2015, p1350 - 1361
Weinert T, Olieric V, Waltersperger S, Panepucci E, Chen L, Zhang H, Zhou D, Rose J, Ebihara A, Kuramitsu S, Li D, Howe N, Schnapp G, Pautsch A, Bargsten K, Prota A.E, Surana P, Kottur J, Nair D.T, Basilico F, Cecatiello V, Pasqualato S, Boland A, Weichenrieder O, Wang B.-C, Steinmetz M.O, Caffrey M, Wang M, Fast native-SAD phasing for routine macromolecular structure determination, Nature Methods, 12, (2), 2015, p131 - 133
Weinert T, Olieric V, Waltersperger S, Panepucci E, Chen L, Zhang H, Zhou D, Rose J, Ebihara A, Kuramitsu S, Li D, Howe N, Schnapp G, Pautsch A, Bargsten K, Prota A.E, Surana P, Kottur J, Nair D.T, Basilico F, Cecatiello V, Pasqualato S, Boland A, Weichenrieder O, Wang B.-C, Steinmetz M.O, Caffrey M, Wang M, Erratum: Fast native-SAD phasing for routine macromolecular structure determination (Nature Methods (2015) 12 (131-133)), Nature Methods, 12, (7), 2015, p692-
Caffrey, M., A comprehensive review of the lipid cubic phase or in meso method for crystallizing membrane and soluble proteins and complexes, Acta Crystallographica Section F Structural Biology Communications, 71, 2015, p3 - 18
Johner, N, Mondal, S, Morra, G, Caffrey, M, Weinstein, H, Khelashvili, G, Protein and Lipid Interactions Driving Molecular Mechanisms of in meso Crystallization, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136, (8), 2014, p3271-3284
Takeda, H. Hattori, M. Nishizawa, T. Yamashita, K. Shah, S.T.A. Caffrey, M. Maturana, A.D. Ishitani, R. Nureki, O., Structural basis for ion selectivity revealed by high-resolution crystal structure of Mg2+ channel MgtE, Nature Communications, 5, 2014, p5374-
Lyons, J.A. Parker, J.L. Solcan, N. Brinth, A. Li, D. Shah, S.T. Caffrey, M. Newstead, S., Structural basis for polyspecificity in the POT family of proton-coupled oligopeptide transporters, EMBO Reports, 15, (8), 2014, p886 - 893
Caffrey, M., Li, D., Howe, N., Shah, S.T.A., Hit and run' serial femtosecond crystallography of a membrane kinase in the lipid cubic phase, Philosophical Transactions of the Royal Society B: Biological Sciences, 369, (1647), 2014, 20130621-
Caffrey M, Li D, Howe N, Shah S.T.A, 'Hit and run' serial femtosecond crystallography of a membrane kinase in the lipid cubic phase, Philosophical Transactions of the Royal Society B: Biological Sciences, 369, (1647), 2014
Li, DF, Howe, N, Dukkipati, A, Shah, STA, Bax, BD, Edge, C, Bridges, A, Hardwicke, P, Singh, OMP, Giblin, G, Pautsch, A, Pfau, R, Schnapp, G, Wang, MT, Olieric, V, Caffrey, M, Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy, CRYSTAL GROWTH & DESIGN, 14, (4), 2014, p2034-2047
Tan, J. Rouse, S.L. Li, D. Pye, V.E. Vogeley, L. Brinth, A.R. El Arnaout, T. Whitney, J.C. Howell, P.L. Sansom, M.S.P. Caffrey, M., A conformational landscape for alginate secretion across the outer membrane of Pseudomonas aeruginosa, Acta Crystallographica Section D Biological Crystallography, 70, (8), 2014, p2054 - 2068
Weierstall, U., James, D., Wang, C., (...), Caffrey, M., Cherezov, V., Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography, Nature Communications, 5, 2014, p3309-
Nji, E. Li, D. Doyle, D.A. Caffrey, M., Cloning, expression, purification, crystallization and preliminary X-ray diffraction of a lysine-specific permease from Pseudomonas aeruginosa, Acta Crystallographica Section F Structural Biology Communications, 70, 2014, p1362 - 1367
Boland, C. Li, D. Shah, S.T.A. Haberstock, S. Dötsch, V. Bernhard, F. Caffrey, M., Cell-free expression and in meso crystallisation of an integral membrane kinase for structure determination, Cellular and molecular life sciences : CMLS71, 24, 2014, p4895-4910
Caffrey, M. Eifert, R. Li, D. Howe, N., The lipid cubic phase or in meso method for crystallizing proteins. Bushings for better manual dispensing, Journal of Applied Crystallography, 47, (5), 2014, p1804 - 1806
Li, D. Caffrey, M., Renaturing membrane proteins in the lipid cubic phase, a nanoporous membrane mimetic, Scientific Reports, 4, 2014, p5806-
Hopper, JTS, Yu, YTC, Li, DF, Raymond, A, Bostock, M, Liko, I, Mikhailov, V, Laganowsky, A, Benesch, JLP, Caffrey, M, Nietlispach, D, Robinson, CV, Detergent-free mass spectrometry of membrane protein complexes, NATURE METHODS, 10, (12), 2013, p1206-+
Li, DF, Lyons, JA, Pye, VE, Vogeley, L, Aragao, D, Kenyon, CP, Shah, STA, Doherty, C, Aherne, M, Caffrey, M, Crystal structure of the integral membrane diacylglycerol kinase, Nature, 497, (7450), 2013, p521-524
Li, DF, Shah, STA, Caffrey, M, Host Lipid and Temperature as Important Screening Variables for Crystallizing Integral Membrane Proteins in Lipidic Mesophases. Trials with Diacylglycerol Kinase, CRYSTAL GROWTH & DESIGN, 13, (7), 2013, p2846-2857
Liu, W., Wacker, D., Gati, C., (...), Stevens, R.C., Cherezov, V., Serial femtosecond crystallography of G protein-coupled receptors, Science, 342, (6165), 2013, p1521-1524
Crystallizing membrane proteins for structure-function studies using lipidic mesophases in, editor(s)Randy,Urzhumtsev A.G.,Alexandre A.G.,Lunin V.Y. , NATO Science for Peace and Security Series A: Chemistry and Biology, 2013, pp33-46 , [Caffrey, M.]
Li, D., Boland, C., Walsh, K., Caffrey, M., Use of a Robot for High-throughput Crystallization of Membrane Proteins in Lipidic Mesophases, Journal of Visualised Experiments, 67, 2012, pe4000
Khelashvili, G, Albornoz, PBC, Johner, N, Mondal, S, Caffrey, M, Weinstein, H, Why GPCRs behave differently in cubic and lamellar lipidic mesophases, Journal of the American Chemical Society, 134, (38), 2012, p15858-15868
Li D, Boland C, Aragao D, Walsh K, Caffrey M, Harvesting and cryo-cooling crystals of membrane proteins grown in lipidic mesophases for structure determination by macromolecular crystallography., Journal of visualized experiments : JoVE, (67), 2012, pe4001
Aherne, M, Lyons, JA, Caffrey, M, A fast, simple and robust protocol for growing crystals in the lipidic cubic phase, Journal of Applied Crystallography , 45, (6), 2012, p1330-1333
Caffrey M, Li D, Dukkipati A, Membrane protein structure determination using crystallography and lipidic mesophases: recent advances and successes., Biochemistry, 51, (32), 2012, p6266-88
Lyons JA, Aragão D, Slattery O, Pisliakov AV, Soulimane T, Caffrey M, Structural insights into electron transfer in caa3-type cytochrome oxidase., Nature, 487, (7408), 2012, p514-8
Dianfan Li, Martin Caffrey, Lipid cubic phase as a membrane mimetic for integral membrane protein enzymes, PNAS, 108, (21), 2011, p8639-8644
Caffrey M, Crystallizing membrane proteins for structure-function studies using lipidic mesophases., Biochemical Society transactions, 39, (3), 2011, p725-32
Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah ST, Lyons JA, Caffrey M, Gellman SH, Steyaert J, Skiniotis G, Weis WI, Sunahara RK, Kobilka BK, Crystal structure of the ß2 adrenergic receptor-Gs protein complex., Nature, 477, (7366), 2011, p549-55
Höfer, N., Aragão, D., Caffrey, M. , The lipidic cubic phase as a membrane mimetic, Biophysical Journal , 100, (8), 2011, p2075 -
Li, DF, Lee, J, Caffrey, M, Crystallizing Membrane Proteins in Lipidic Mesophases. A Host Lipid Screen, CRYSTAL GROWTH & DESIGN, 11, (2), 2011, p530-537
Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, Rasmussen SG, Choi HJ, Devree BT, Sunahara RK, Chae PS, Gellman SH, Dror RO, Shaw DE, Weis WI, Caffrey M, Gmeiner P, Kobilka BK, Structure and function of an irreversible agonist-ß(2) adrenoceptor complex., Nature, 469, (7329), 2011, p236-40
Li D, Caffrey M, Lipid cubic phase as a membrane mimetic for integral membrane protein enzymes., Proceedings of the National Academy of Sciences of the United States of America, 108, (21), 2011, p8639-44
Höfer N, Aragão D, Lyons JA, Caffrey M., Membrane Protein Crystallization in Lipidic Mesophases. Hosting lipid affects on the crystallization and structure of a transmembrane peptide., Cryst Growth Design, 11, (4), 2011, p1182-1192
Höfer N, Aragão D, Caffrey M, Crystallizing membrane proteins for structure determination using lipidic mesophases. , Journal of Visualized Experiments, 45, 2010, p1712-
Höfer N, Aragão D, Caffrey M, Crystallizing Transmembrane Peptides in Lipidic Mesophases, Biophysical Journal, 99, (3), 2010, pL23-L25
Luan B, Carr R, Caffrey M, Aksimentiev A, The effect of calcium on the conformation of cobalamin transporter BtuB., Proteins, 78, (5), 2010, p1153-62
Monoacylglycerols: The Workhorse Lipids for Crystallizing Membrane Proteins in Mesophases in, editor(s)Dale J. Benos; Sidney A. Simon , Current Topics in Membranes, San Diego, Elsevier, 2009, pp83-108 , [M. Caffrey, J. Lyons, T. Smyth and D.J. Hart]
Caffrey M, Cherezov V, Crystallizing membrane proteins using lipidic mesophases., Nature Protocols, 4, (5), 2009, p706-31
Caffrey M, Crystallizing membrane proteins for structure determination: use of lipidic mesophases., Annual Review of Biophysics, 38, 2009, p29-51
Cherezov V, Höfer N, Szebenyi DM, Kolaj O, Wall JG, Gillilan R, Srinivasan V, Jaroniec CP, Caffrey M, Insights into the mode of action of a putative zinc transporter CzrB in Thermus thermophilus., Structure (London, England : 1993), 16, (9), 2008, p1378-88
Cherezov V, Liu W, Derrick JP, Luan B, Aksimentiev A, Katritch V, Caffrey M, In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin., Proteins, 71, (1), 2008, p24-34
Martin Caffrey, On the Mechanism of Membrane Protein Crystallization in Lipidic Mesophases, Crystal Growth and Design, 8, (12), 2008, p4244-4254
Luan, B., Caffrey, M., Aksimentiev, A., Structural Refinement of the OpcA Adhesin Using Molecular Dynamics., Biophysics Journal, 93, 2007, p3058-3069
Boyle-Roden, E., Hoefer, N., Dey, K. K., Grandinetti, P. J., Caffrey, M., High resolution 1H NMR of a lipid cubic phase using a solution NMR probe, Journal of Magnetic Resonance, 189, 2007, p13-19
A general robotic approach for high-throughput automation in the handling of biosamples. in, editor(s)Eds Zhang, M., Nelson, B., Felder, R., , Life Science Automation - Fundamental and Applications., Norwood, MA. , Artech House, 2007, pp395-409 , [Zheng, Y.F., Peddi, A. Muthusubramaniam, L., Cherezov, V., and Caffrey, M.]
Cherezov, V., Caffrey, M. , Membrane Protein Crystallization in Lipidic Mesophases. A Mechanism Study Using X-ray Microdiffraction. , Faraday Discussions, 136, 2007, p188-205
Höfer, N., Kolaj, O., Li, H., Cherezov, V., Gillilan, R., Wall, J., Caffrey, M., Crystallization and preliminary X-ray diffraction analysis of a soluble domain of the putative zinc transporter CzrB from Thermus thermophilus., Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 63, (8), 2007, p673-677
Yuan L., Zheng, Y.F., Chen. W., and Caffrey, M. , Automatic Mixing of Bio-Samples Using Micro-Channel and Centrifugation , Proc. IEEE Conference on Automation Science and Engineering,, IEEE Conference on Automation Science and Engineering,, Scottsdale, AZ, September 22-25, IEEE, 2007, pp634-639
Miniaturization and Automation for High-throughput Membrane Protein Crystallization in Lipidic Mesophases. in, editor(s)Chayen. N. , Crystallization Strategies for Structural Genomics, 2007, pp169-194 , [Cherezov, V., Caffrey, M.]
M. Peddi, A., Muthusubramaniam, L., Zheng, Y. F., Cherezov, V., Caffrey,, High-throughput Automated System for Crystallizing Membrane Proteins in Lipidic Mesophases., IEEE Transactions on Automation Science and Engineering, 4, (2), 2007, p129-140
Caffrey, M., Bernal and the genesis of structural biology. , Journal of Physics: Conference Series, 57, 2007, p17-28
Cherezov, V., Clogston, J., Papiz, M., Caffrey, M., Room to move. Crystallizing membrane proteins in swollen lipidic mesophases., Journal of Molecular Biology, 357, 2006, p1605-1618
Cherezov, V., Caffrey, M., Picoliter-scale Crystallization of Membrane Proteins., Journal of Applied Crystallography, 39, (4), 2006, p604-609
Liu, W., Caffrey, M. , Interactions of tryptophan, tryptophan peptides and tryptophan alkyl esters at curved membrane interfaces., Biochemistry , 45, (39), 2006, p11713-11726
Raman, P., Cherezov, V., Caffrey, M., The Membrane Protein Data Bank., Cellular and Molecular Life Sciences, 63, (1), 2006, p36-51.
Cherezov, V., Yamashita, E., Liu, W., Zhalnina, M., Cramer, W. A., Caffrey, M., In Meso Structure of the Cobalamin Transporter, BtuB, at 1.95 Å Resolution. , Journal of Molecular Biology, 364, (4), 2006, p716-734
Siegel, D. P., Cherezov, V., Greathouse, D. V., Koeppe II, R. E., Killian, J. A., Caffrey, M. , Transmembrane Peptides Stabilize Inverted Cubic Phases in a Biphasic Length-dependent Manner: Implications for Protein-induced Membrane Fusion., Biophysical Journal, 90, 2006, p200-211
Clogston, J., Graciun, G., Hart, D. J., Caffrey, M., Controlling Release from the Lipidic Cubic Phase by Selective Alkylation., Journal of Controlled Release, 102, (2), 2005, p441-461
Cherezov, M., Caffrey, M., A simple and inexpensive nanoliter volume dispenser for highly viscous materials used in membrane protein crystallization., Journal of Applied Crystallography, 38, 2005, p398-400
Caffrey, M., The Membrane Protein Data Bank. - An on-line, searchable, relational database with select structural and functional information on membrane proteins and peptides. , 2005, -
Liu, W., Caffrey, M, Gramicidin Structure and Disposition in Highly Curved Membranes. , Journal Structural Biology, 150, (1), 2005, p23-40
Misquitta, Y., Cherezov, V., Havas, F., Patterson, S., Mohan, J., Wells, A., Hart, D., Caffrey, M., Rational Design of Lipid for Membrane Protein Crystallization. , Journal of Structural Biology, 148, (2), 2004, p169-175
Misquitta, L.V., Misquitta, Y., Cherezov, V., Slattery, O., Mohan, J. M., Hart, D., Zhalnina, M., Cramer, W. A., Caffrey, M., Membrane protein crystallization in lipidic mesophases with tailored bilayers. , Structure, 12, (12), 2004, p2113-2124
*Cherezov, V., Peddi, A., Muthusubramaniam, L., Zheng, Y.F. M. Caffrey., A Robotic System For Crystallizing Membrane And Soluble Proteins In Lipidic Mesophases., Acta Crystallographica Section D, 60, (10), 2004, p1795-1807
Caffrey, M., Membrane Protein Crystallization, Journal of Structural Biology, 142, (1), 2003, p108-132
Cherezov, V., D. P. Siegel, W. Shaw, S. W. Burgess and M. Caffrey. , The kinetics of non-lamellar phase formation in dope-me: relevance to biomembrane fusion., Journal of Membrane, 195, (3), 2003, p165-182
Ravelli, R.B.G. and Leiros, H.-K.S. and Pan, B. and Caffrey, M. and McSweeney, S., Specific radiation damage can be used to solve macromolecular crystal structures, Structure, 11, (2), 2003, p217-224
Misquitta, Y., Caffrey, M., Detergents Destabilize the Cubic Phase of Monoolein. Implications for Membrane Protein Crystallization., Biophysical Journal, 85, (5), 2003, p3084-3096
Cherezov, V., Caffrey, M., Nano-volume Plates with Excellent Optical Properties for Fast, Inexpensive Crystallization Screening of Membrane Proteins., Journal of Applied Crystallography, 36, 2003, p1372-1377
Cherezov, V. and Clogston, J. and Misquitta, Y. and Abdel-Gawad, W. and Caffrey, M., Membrane protein crystallization in meso: Lipid type-tailoring of the cubic phase, Biophysical Journal, 83, (6), 2002, p3393-3407
Brzustowicz, M.R. and Cherezov, V. and Caffrey, M. and Stillwell, W. and Wassall, S.R., Molecular organization of cholesterol in polyunsaturated membranes: Microdomain formation, Biophysical Journal, 82, (1), 2002, p285-298
Cherezov, V. and Qiu, H. and Pector, V. and Vandenbranden, M. and Ruysschaert, J.-M. and Caffrey, M., Biophysical and transfection studies of the diC
Koynova, R. and Caffrey, M., Erratum: Phases and phase transitions of the phosphatidylcholines (Biochimica et Biophysica Acta (1998) 1376 (91-145) PII: S0304415798000069), Biochimica et Biophysica Acta - Biomembranes, 1513, (1), 2001, p82
Misquitta, Y. and Caffrey, M., Rational design of lipid molecular structure: A case study involving the C19:1c10 monoacylglycerol, Biophysical Journal, 81, (2), 2001, p1047-1058
Cherezov, V. and Fersi, H. and Caffrey, M., Crystallization screens: Compatibility with the lipidic cubic phase for in meso crystallization of membrane proteins, Biophysical Journal, 81, (1), 2001, p225-242
Ai, X. and Caffrey, M., Membrane protein crystallization in lipidic mesophases: Detergent effects, Biophysical Journal, 79, (1), 2000, p394-405
Caffrey, M, A lipid's eye view of membrane protein crystallization in mesophases., Current Opinion in Structural Biology, 10, (4), 2000, p486-497
Zhang, R. and Itri, R. and Caffrey, M., Membrane structure characterization using variable-period x-ray standing waves, Biophysical Journal, 74, (4), 1998, p1924-1936
Itri, R. and Zhang, R. and Caffrey, M., Spatial resolution of the variable-period x-ray standing-wave method as applied to model membranes, Biophysical Journal, 73, (3), 1997, p1506-1515
Cheng, A. and Caffrey, M., Free radical mediated x-ray damage of model membranes, Biophysical Journal, 70, (5), 1996, p2212-2222
Caffrey, M., Lipid Data Bank. - A relational database of thermodynamic data on lipid mesophase and crystal polymorphic transitions on the Web. , 1996, -
Chung, H. and Caffrey, M., Polymorphism, mesomorphism, and metastability of monoelaidin in excess water, Biophysical Journal, 69, (5), 1995, p1951-1963
Cheng, A. and Hummel, B. and Mencke, A. and Caffrey, M., Kinetics and mechanism of the barotropic lamellar gel/lamellar liquid crystal phase transition in fully hydrated dihexadecylphosphatidylethanolamine: a time-resolved x-ray diffraction study using pressure jump, Biophysical Journal, 67, (1), 1994, p293-303
Briggs, J. and Caffrey, M., The temperature-composition phase diagram of monomyristolein in water: equilibrium and metastability aspects, Biophysical Journal, 66, (3), 1994, p573-587
Wang, J., C. Wallace, I. Clark-Lewis, M. Caffrey , Structure characterization of membrane bound and surface adsrobed protein, Journal of Molecular Biology, 237, (1), 1994, p1-4
*Chung, H., M. Caffrey , Curvature elastic energy fn. of cubic mesophase, Nature, 368, (6468), 1994, p224-226.
Chung, H. and Caffrey, M., The neutral area surface of the cubic mesophase: location and properties, Biophysical Journal, 66, (2), 1994, p377-381
Briggs, J. and Caffrey, M., The temperature-composition phase diagram and mesophase structure characterization of monopentadecenoin in water, Biophysical Journal, 67, (4), 1994, p1594-1602
Caffrey, M., Lipid thermotropic phase transitions LIPIDAT. NIST Standard Reference Database 34. , 1993, -
Zhu, T. and Caffrey, M., Thermodynamic, thermomechanical, and structural properties of a hydrated asymmetric phosphatidylcholine, Biophysical Journal, 65, (2), 1993, p939-954
Mencke, A., Cheng, A-c. and Caffrey, M. , A simple apparatus for time-resolved x-ray diffraction studies utilizing static pressures and pressure-jumps up to 300 MPa, Review of Science Instruments, 64, 1993, p383-389
Koynova, R. and Caffrey, M., Mesophase transition temperatures as measured by fluorescence and calorimetry, Biophysical Journal, 65, (1), 1993, p550
Caffrey, M. , LIPIDAT A database of thermodynamic data and associated information on lipid mesomorphic and polymorphic transitions. , Boca Raton, FL., CRC Press, Inc, 1993, 1 - 305pp
Cheng, A., J. L. Hogan, M. Caffrey , X-Rays destroy membrane structure., Journal of Molecular Biology, 229, (2), 1993, p291-294
*Wang, J., M.Bedzyk, M. Caffrey , Resonance-Enhanced X-Rays, Science, 258, (5083), 1992, p775-778
Lynch DV, Caffrey M, Hogan J, Steponkus PL, Calorimetric and x-ray diffraction studies of rye glucocerebroside mesomorphism, Biophysical Journal, 61, (5), 1992, p1289-1300
Caffrey, M. and Hogan, J., LIPIDAT: A database of lipid phase transition temperatures and enthalpy changes. DMPC data subset analysis. , Chem. Phys. Lipids, 61, 1992, p1-109
Chung H, Caffrey M, Direct correlation of structure changes and thermal events in hydrated lipid established by simultaneous calorimetry and time-resolved x-ray diffraction., Biophysical journal, 63, (2), 1992, p438-47
Mencke AP, Caffrey M, Kinetics and mechanism of the pressure-induced lamellar order/disorder transition in phosphatidylethanolamine: a time-resolved X-ray diffraction study., Biochemistry, 30, (9), 1991, p2453-63
Wang, J., M. Bedzyk, T. Penner, M. Caffrey , Structural studies of membranes and surface layers up to 1,000 A thick using X-ray standing waves., Nature, 354, (6352), 1991, p377-380
Wang, J., M. Bedzyk, T. Penner, M. Caffrey , Structural studies of membranes and surface layers up to 1,000 A thick using X-ray standing waves., Nature, 354, (6352), 1991, p377-380
Martin Caffrey, Denis Moynihan, Jacqueline Hogan, A database of lipid phase transition temperatures and enthalpy changes., J. Chem. Inf. Comput. Sci., , 31, (2), 1991, p275-284
Caffrey M, Hogan J, Mencke A, Kinetics of the barotropic ripple (P beta')/lamellar liquid crystal (L alpha) phase transition in fully hydrated dimyristoylphosphatidylcholine (DMPC) monitored by time-resolved x-ray diffraction., Biophysical journal, 60, (2), 1991, p456-66
Wang, J., M. Bedzyk, T. Penner, M. Caffrey , Structural studies of membranes and surface layers up to 1,000 A thick using X-ray standing waves., Nature, 354, (6352), 1991, p377-380
Mencke, A. P., M. Caffrey, Kinetics and mechanism of the pressure-induced lamellar order/disorder transition in phosphatidylethanolamine, Biochemistry, 30, (9), 1991, p2453-2463
Caffrey, M., J. L. Hogan, A. S. Rudolph, Diacetylenic lipid microstructures: structural characterization by X-ray diffraction and comparison with the saturated phosphatidylcholine analogue., Biochemistry, 30, (8), 1991, p2134-2146
Caffrey M, Hogan J, Rudolph AS, Diacetylenic lipid microstructures: structural characterization by X-ray diffraction and comparison with the saturated phosphatidylcholine analogue., Biochemistry, 30, (8), 1991, p2134-46
*Bedzyk, M., M. Bommarito, M. Caffrey, T. Penner, Diffuse-Double Layer at a Membrane/Aqueous Interface Measured with X-ray Standing Waves, Science, 248, 1990, p52-56
Bedzyk MJ, Bommarito GM, Caffrey M, Penner TL, Diffuse-double layer at a membrane-aqueous interface measured with x-ray standing waves., Science (New York, N.Y.), 248, (4951), 1990, p52-56
Caffrey M, Magin RL, Hummel B, Zhang J, Kinetics of the lamellar and hexagonal phase transitions in phosphatidylethanolamine. Time-resolved x-ray diffraction study using a microwave-induced temperature jump., Biophysical journal, 58, (1), 1990, p21-9
H. C. Gerritsen, M. Caffrey, Water transport in lyotropic liquid crystals and lipid-water systems: mutual diffusion coefficient determination, Journal of Physical Chemistry, 94, (2), 1990, p944-948
Caffrey, M., Mynihan, D. and Hogan, J., A database of lipid phase transition temperatures and enthalpy changes., Chem Physics Lipids, 57, (2-3), 1990, p275-291
Caffrey M, Fanger G, Magin RL, Zhang J, Kinetics of the premelting (L beta'-P beta') and main transition (P beta'-L alpha) in hydrated dipalmitoylphosphatidylcholine. A time-resolved x-ray diffraction study using microwave-induced temperature-jumps., Biophysical journal, 58, (3), 1990, p677-86
Caffrey, M. , Lipid phase transition kinetics by time-resolved x-ray diffraction., Annual Review of Biophysics and Biophysical Chemistry , 18, 1989, p159-186
Caffrey M, A lyotrope gradient method for liquid crystal temperature-composition-mesomorph diagram construction using time-resolved x-ray diffraction., Biophysical Journal, 55, (1), 1989, p47-52
Caffrey, M. and Bywater, M, Two new and rapid approaches for studying the phase properties of cosmetic lipids and oils, Journal of the Society of Cosmetic Chemists, 39, (3), 1988, p159-167
Caffrey M, Fonseca V, Leopold AC., Lipid-sugar interaction: Relevance to anhydrous biology, Plant Physiology, 86, (3), 1988, p754-758
Bedzyk, M. D.H. Bilderback,, M. Bommarito, M. Caffrey, And J. Schildkraut , X-ray standing waves. A molecular yardstick for biomembranes, Science, 241, (4874), 1988, p1788-1791
Bedzyk MJ, Bilderback DH, Bommarito GM, Caffrey M, Schildkraut JS, X-ray standing waves: a molecular yardstick for biological membranes., Science (New York, N.Y.), 241, (4874), 1988, p1788-91
Caffrey M, The combined and separate effects of low temperature and freezing on membrane lipid mesomorphic phase behavior: relevance to cryobiology., Biochimica et biophysica acta, 896, (1), 1987, p123-127
Caffrey M, Werner BG, Priestley DA, A crystalline lipid phase in a dry biological system: evidence from X-ray diffraction analysis of Typha latifolia pollen., Biochimica et biophysica acta, 921, (1), 1987, p124-34
Caffrey M, Kinetics and mechanism of transitions involving the lamellar, cubic, inverted hexagonal, and fluid isotropic phases of hydrated monoacylglycerides monitored by time-resolved X-ray diffraction., Biochemistry, 26, (20), 1987, p6349-6363
Caffrey M, Hing FS, A temperature gradient method for lipid phase diagram construction using time-resolved x-ray diffraction., Biophysical journal, 51, (1), 1987, p37-46
Caffrey M, Morris SJ, Feigenson GW, Uranyl acetate induces gel phase formation in model lipid and biological membranes., Biophysical Journal, 52, (3), 1987, p501-505
Phoebe Dea, Laurence T. Pearson, Martin Caffrey and Sunney I. Chan, Effect of chlorophyll a on the phase behavior of hydrated monogalactosyl diacylglyceride, Biochimica et Biophysica Acta (BBA) - Biomembranes, 896, (1), 1987, p11-18
Caffrey, M. and Lew, R.R., The Ca2+ induced phase transformation in soybean root microsomal membranes is a consequence of phospholipase activity, Plant Cell Physiology, 27, 1986, p1091-1100
Caffrey M, Kinetics and mechanism of the lamellar gel/lamellar liquid-crystal and lamellar/inverted hexagonal phase transition in phosphatidylethanolamine: a real-time X-ray diffraction study using synchrotron radiation., Biochemistry, 24, (18), 1985, p4826-4844
Martin Caffrey, X-Radiation damage of hydrated lecithin membranes detected by real-time x-ray diffraction using wiggler-enchanced synchrotron radiation as the ionizing radiation source, Nuclear Instruments and Methods in Physics Research, 222, (1-2), 1984, p329-338
Caffrey M, Feigenson GW, Influence of metal ions on the phase properties of phosphatidic acid in combination with natural and synthetic phosphatidylcholines: an X-ray diffraction study using synchrotron radiation., Biochemistry, 23, (2), 1984, p323-31
Caffrey, M and Feigenson, G.W., The influence of metal ions on the phase properties of phosphatidic acid in combination with natural and synthetic phosphatidylcholines: An x-ray diffraction study using synchrotron radiation. , Biochemistry, 23, (2), 1984, p323-331
David T. Grubb, Jay J.-H. Liu, Martin Caffrey, Donald H. Bilderback, Real-time small-angle x-ray scattering during annealing of polymer single crystals. , Journal of Polymer Science: Polymer Physics Edition, 22, (3), 1984, p367-378
Caffrey M, Bilderback DH, Kinetics of the main phase transition of hydrated lecithin monitored by real-time X-ray diffraction., Biophysical journal, 45, (3), 1984, p627-631
Caffrey, M., Bilderback, D.H, Real-time X-ray diffraction using synchrotron radiation: System characterization and applications, Nuclear Instruments and Methods In Physics Research, 208, (1-3), 1983, p495-510
Caffrey, M and Feigenson, G.W., Fatty acyl chain characteristics of phosphatidylcholines affect Ca2+-ATPase enzymatic activity but not the affinity of the protein for these different lipid species., Biochemical Society Transactions, 9, 1981, p155-156
Caffrey M, Feigenson GW, Fluorescence quenching in model membranes. 3. Relationship between calcium adenosinetriphosphatase enzyme activity and the affinity of the protein for phosphatidylcholines with different acyl chain characteristics., Biochemistry, 20, (7), 1981, p1949-1961
Caffrey M, Kinsella JE, Properties of palmitoyl-CoA: monopalmitoyl-sn-glycerol 3-phosphate palmitoyltransferase from rabbit mammary gland., The International journal of biochemistry, 9, (4), 1978, p239-48
Caffrey MC, Kinsella JE, Solubilization of a micelle specific acyltransferase from rat mammary microsomes., The International journal of biochemistry, 9, (6), 1978, p381-384
Caffrey, M. & Kinsella, JE., Kinetics of a micelle specific palmitoyltransferase isoenzyme from rabbit mammary gland., Lipids, 12, 1977, p556-562
Caffrey, M. & Kinselaa, JE., Experimental difficulties in assaying a membrane-bound acyltransferase from rabbit mammary tissue, International Journal of Biochemistry, 8, 1977, p39-51
Caffrey M. & Kinsella, JE, Growth and acyltransferase activity of rabbit mammary gland during pregnancy and lactation, Journal of Lipid Research, 18, (1), 1977, p44-52.
Caffrey, M, Kinsella, JE, Isoenzymes of an acyltransferase from rabbit mammary gland: Solubilization of the micelle-specific species with Tritron X-100, Biochemical and Biophysical Research Communications, 71, 1976, p484-491
Caffrey, M., Infante, J. and Kinsella, J. E. , Isoenzymes of an acyltransferase from rabbit mammary gland: Evidence from biphasic substrate saturation kinetics., FEBS Letters, 52, (1), 1975, p116-120
Caffey M. & Kinsella, JE., Sensitivity of the molar absortivity value to sample and instrument characteristics, with reference to the Ellman Reagent (DTNB), International Journal of Biochemistry, 6, 1975, p877-883
Research Expertise
Projects
- Title
- Structure-Function Studies of Membrane Proteins Involved in Quorum Sensing and the Pathogenicity of Pseudomonas aeruginosa
- Summary
- SFI: Investigatorship Award. PI, M. Caffrey. Direct costs 2,521,216. The major goal of this project is to crystallize and to solve the X-ray structure of a select group of membrane proteins involved in quorum sensing and the pathogenicity of Pseudomonas aeruginosa. There is no overlap with the current proposal.
- Funding Agency
- SFI
- Date From
- 01/06/08
- Date To
- 31/05/13
- Title
- Membrane Proteins. Crystallogenesis and X-ray Structure
- Summary
- PI, M. Caffrey. Direct costs $187,500/year. Total costs $202,500/year. Instrumentation Supplement awarded 2008, 15,000 The purpose of this project is to develop and to implement the lipidic mesophase method for membrane protein crystallogenesis.
- Funding Agency
- NIH
- Date From
- 01/09/05
- Date To
- 31/08/10.
- Title
- Robotic Dispensing of Cubic Phase for Crystallizing Membrane Proteins
- Summary
- Co-PI with Y. Zheng, Electrical Engineering, OSU.
- Funding Agency
- NSF
- Date From
- 7/2003
- Date To
- 7/2007
- Title
- The Structural Biology of Membrane Proteins
- Summary
- PI, M. Caffrey. . Total Award, 2.45m. The purpose of this award was to enable the PI to establish a research program in the area of membrane structural and functional biology at The University of Limerick, Ireland. The bulk of the funding for this project was directed to equipping the lab at UL with X-ray and other biochemical/biophysical instrumentation, and to support a limited number of personnel. The University of Limerick does not have a strong tradition in fundamental research in the biosciences. The PI's charge is to contribute to getting such activity underway. His appointment at UL is strictly a research position and does not require teaching.
- Funding Agency
- SFI
- Date From
- 11/2003
- Date To
- 05/2008
- Title
- Marie Curie. Intra European Fellowship.
- Summary
- 133,440.77. Postdoc funding for Dr. D. Aragao. Commission Des Communautes
- Funding Agency
- Marie Curie
- Date From
- 01/05/09
- Date To
- 30/04/11
- Title
- Structure-Function Studies of Membrane Proteins Involved in Quorum Sensing and the Pathogenicity of Pseudomonas aeruginosa
- Summary
- PI, M. Caffrey. . Direct costs 2,521,216.
- Funding Agency
- SFI
- Date From
- 01/06/08
- Date To
- 31/05/13
- Title
- Membrane Proteins. Crystallogenesis and X-ray Structure
- Summary
- PI, M. Caffrey. Direct costs $187,500/year. Total costs $202,500/year.
- Funding Agency
- NIH
- Date From
- 01/09/05
- Date To
- 31/08/10.
- Title
- SFI. Strategic Research Cluster.
- Summary
- PI, K. Dawson (UCD). Total award, 7,241,740. Collaborator, M. Caffrey along with several others, 250,000. BioNanoInteractions: Interactions of engineered nanoparticles with biological systems - a rational basis for nanotoxicology and nanomedicine.
- Funding Agency
- SFI
- Title
- SFI. Equipment Supplement.
- Summary
- PI, M. Caffrey. 264,218, 1,500 Plate-capacity Automatic Crystallization Plate Imager
- Funding Agency
- SFI
- Date From
- 12/2007
- Date To
- 05/2008
- Title
- SFI. Undergraduate Research Experience and Knowledge Awards.
- Summary
- PI, M. Caffrey. 6,300, 02/in.1/B266ur7.2, Bishal Singh. 5,300, 02/in.1/B266ur7.1, Zuzanna Kurowska The structure and function of membrane proteins 05/08 - 09/08, 5,600, 02/IN1/B266 UR08, Rachel Tiedt. Synthesis of lipids for use in in meso crystallogenesis.
- Funding Agency
- SFI
- Date From
- 05/2007
- Date To
- 09/2008
- Title
- A Web-based Relational Database for Thermodynamic Data on Lipid Mesomorphase Transitions and Miscibility. Supplement to Support Workshop "Databases for Biophysicists" at Biophysical Society Meeting, Boston, MA.
- Summary
- NSF; DBI 9981990; PI, M. Caffrey; $21,597.
- Funding Agency
- NSF
- Date From
- 1/2000
- Date To
- 12/2002
- Title
- A Web-based Relational Database for Thermodynamic Data on Lipid Mesomorphase Transitions and Miscibility.
- Summary
- PI, M. Caffrey; $444,441.
- Funding Agency
- NSF
- Date From
- 01/2000
- Date To
- 12/2003
- Title
- Cooperative Science and Technology Sub-Programme COLLABORATIVE LINKAGE GRANT,
- Summary
- $9,500. A web-based database for thermodynamic and structure data on lipids.
Grant awarded but declined.
- $9,500. A web-based database for thermodynamic and structure data on lipids.
- Date From
- 03/2000
- Date To
- 02/2002
- Title
- Membrane Protein Structure. Use of lipidic mesophases,
- Summary
- $928,344. The major goals of this project weas to decipher the mechanism of membrane protein crystallization and to implement it in the crystallization of membrane proteins.
- Funding Agency
- NIH
- Date From
- 1/2001
- Date To
- 12/2005
- Title
- Membrane Protein Structure. Use of lipidic mesophases
- Summary
- $928,344. The major goals of this project weas to decipher the mechanism of membrane protein crystallization and to implement it in the crystallization of membrane proteins.
- Funding Agency
- NIH
- Date From
- 1/2001
- Date To
- 12/2005
- Title
- Short term proposal (1 quarter) proposal:Toward an understanding of the mechanism of x-radiation damage to lipids and membranes. Proposal written by MC.
- Summary
- ESRF, Grenoble, France. Co-PIs: O. Diat, J-M Petit. . 4 days of beamtime approved.
- Date From
- 9/1999
- Date To
- Active in 2000.
- Title
- Long Term (3 year) proposal: Toward an understanding of the mechanism of x-radiation damage to protein crystals. Proposal written by MC.
- Summary
- ESRF, Grenoble, France. Co-PIs: S. McSweeney, R. Ravelli, E. Garmon. 3 weeks of beamtime approved.
- Date From
- 2001
- Title
- Long Term (2 year) proposal: Toward an understanding of the mechanism of x-radiation damage to protein crystals. Proposal written by MC.
- Summary
- ESRF, Grenoble, France. Co-PIs: S. McSweeney, R. Ravelli, E. Garmon. 2 weeks of beamtime approved for use as short-term proposal. Beamtime used in Summer 2000.
- Date To
- Summer 2000
- Title
- A Relational Database for Thermodynamic and Structure Data on Lipids.
- Summary
- PI, M. Caffrey;. $241,562.
- Funding Agency
- NSF;
- Date From
- 9/1995
- Date To
- 08/2000
- Title
- Membrane Fusion. Intermediates and transbilayer peptides.
- Summary
- $1,031,267.
- Funding Agency
- NIH.
- Date From
- 12/01/97
- Date To
- 11/30/01
- Title
- Membrane disposition of cytochrome c.
- Summary
- Summer 99, $5,000.
- Funding Agency
- Faculty Summer Research Program. Petroleum Research Fund, American Chemical Society
- Date To
- 1999
- Title
- National Synchrotron Light Source, Beamtime Proposal
- Summary
- 70 days of beamtime approved on beam line X15A. .
- Date From
- 6/1995
- Date To
- 5/1997
- Title
- National Synchrotron Light Source
- Summary
- Beamtime Proposal, 2/95. 24 days of beamtime approved on beam line X9B.
- Date From
- 6/1995
- Date To
- 5/1997
- Title
- An environmentally sensitive method using biocmpatible absorbent materials for water treatemnet.
- Summary
- PI: Caffrey, Co-PIs: J. Rathman, D. Tomasko, H. Walker. $80,000.
- Funding Agency
- OSU Office of Research Seed Grant
- Date From
- 5/1997
- Date To
- 12/2001
- Title
- Research Experience for Undergraduate Students (REU Award)
- Summary
- $5,000, Summer internship support for Ms. Perryman from Spellman College, Atlanta, GA.
- Funding Agency
- NSF
- Date From
- 6/1996
- Date To
- 9/1996
- Title
- Membrane disposition of cytochrome c - An x-ray standing wave study.
- Summary
- Petroleum Research Fund, American Chemical Society, , $50,000.
- Funding Agency
- Petroleum Research Fund
- Date From
- 5/1996
- Date To
- 5/1998
- Title
- Postdoctoral Fellow
- Summary
- $20,500/annum from the Government of Brazil to support Dr. R. Itri from University of Sao Paolo, (M. Caffrey, Sponsor)
- Funding Agency
- Government of Brazil
- Date From
- 1995
- Date To
- 1997