Professor Dermot P Kelleher
Adjunct Professor, School Office - Medicine
Adjunct Professor, Clinical Medicine
Publications and Further Research Outputs
Peer-Reviewed Publications
Tambunting, L. and Kelleher, D. and Duggan, S.P., The Immune Underpinnings of Barrett's-Associated Adenocarcinogenesis: a Retrial of Nefarious Immunologic Co-Conspirators, Cellular and Molecular Gastroenterology and Hepatology, 13, (5), 2022, p1297-1315
Purification of Total RNA from Stomach Tissue Biopsies. in, Methods Mol Biol. 2283, 2021, pp51 - 59, [FitzGerald R, Devapal M, Hickey JJ, McNamara D, Kelleher D, Smith SM.]
Coleman C, Quinn E.M, Ryan A.W, Conroy J, Trimble V, Mahmud N, Kennedy N, Corvin A.P, Morris D.W, Donohoe G, O'Morain C, MacMathuna P, Byrnes V, Kiat C, Trynka G, Wijmenga C, Kelleher D, Ennis S, Anney R.J.L, McManus R, Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci, European Journal of Human Genetics, 24, 2016, p291 - 297
L.E. Collins, M Lynch, I Marszalowska, M. Kristek, K. Rochfort, M. O'Connell, H.J. Windle, D. Kelleher, C.E. Loscher, Surface layer proteins isolated from Clostridium difficile induce clearance responses in macrophages, Microbes and Infection, 2014
Májer F, Sharma R, Mullins C, Keogh L, Phipps S, Duggan S, Kelleher D, Keely S, Long A, Radics G, Wang J, Gilmer JF, New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid., Bioorganic & medicinal chemistry, 22, (1), 2014, p256-68
McCarthy, S.E., Gillis, J., Kramer, M., (...), McCombie, W.R., Corvin, A. , De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability, Molecular Psychiatry, 19, 2014, p652-658
Ruiz, JFM, Kedziora, K, Pigott, M, Keogh, B, Windle, H, Gavin, J, Kelleher, DP, Gilmer, JF, A nitrophenyl-based prodrug type for colorectal targeting of prednisolone, budesonide and celecoxib, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 23, (6), 2013, p1693-1698
Queiroz, D.M.M., Harris, P.R., Sanderson, I.R., Windle, H.J., Walker, M.M., Rocha, A.M.C., Rocha, G.A., (...), Crabtree, J.E, Iron Status and Helicobacter pylori Infection in Symptomatic Children: An International Multi-Centered Study, PLoS ONE , 8, (7), 2013, art. no. e68833
Grealy, R., White, M., Stordeur, P., Kelleher, D., Doherty, D.G., McManus, R., Ryan, T., Characterising cytokine gene expression signatures in patients with severe sepsis, Mediators of Inflammation, 2013, 2013, part. no. 164246
Gavin, J, Ruiz, JFM, Kedziora, K, Windle, H, Kelleher, DP, Gilmer, JF, Structure requirements for anaerobe processing of azo compounds: Implications for prodrug design, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 22, (24), 2012, p7647-7652
Ruiz, JFM, Kedziora, K, O'Reilly, M, Maguire, J, Keogh, B, Windle, H, Kelleher, DP, Gilmer, JF, Azo-reductase activated budesodine prodrugs for colon targeting, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 22, (24), 2012, p7573-7577
Verma NK, Dempsey E, Long A, Davies A, Barry SP, Fallon PG, Volkov Y, Kelleher D, Leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction induces a novel genetic signature resulting in T-cells refractory to transforming growth factor-ß signaling., The Journal of biological chemistry, 287, (32), 2012, p27204-16
Petrovic D, Dempsey E, Doherty DG, Kelleher D, Long A, Hepatitis C virus - T-cell responses and viral escape mutations., European journal of immunology, 42, (1), 2012, p17-26
Byrne AM, Sharma R, Duggan G, Kelleher D, Long A, Deoxycholic acid impairs glycosylation and fucosylation processes in esophageal epithelial cells., Glycobiology, 22, (5), 2012, p638-648
O'Riordan AA, Morales VA, Mulligan L, Faheem N, Windle HJ, Kelleher DP, Alkyl hydroperoxide reductase: a candidate Helicobacter pylori vaccine., Vaccine, 30, (26), 2012, p3876-84
Kelleher, D., Dendrimers branch out to support mucosal integrity, EMBO Molecular Medicine , 4, (9), 2012, p860-862
Verma, N.K., Conroy, J., Lyons, P.E., Coleman, J., O'Sullivan, M.P., Kornfeld, H., Kelleher, D., Volkov, Y., Autophagy induction by silver nanowires: A new aspect in the biocompatibility assessment of nanocomposite thin films, Toxicology and Applied Pharmacology, 164, (3), 2012, p451-461
Mohamed BM, Verma NK, Davies AM, McGowan A, Crosbie-Staunton K, Prina-Mello A, Kelleher D, Botting CH, Causey CP, Thompson PR, Pruijn GJ, Kisin ER, Tkach AV, Shvedova AA, Volkov Y, Citrullination of proteins: a common post-translational modification pathway induced by different nanoparticles in vitro and in vivo., Nanomedicine (London, England), 7, (8), 2012, p1181-1195
Su, Z, Gay, LJ, Strange, A, Palles, C, Band, G, Whiteman, DC, Lescai, F, Langford, C, Nanji, M, Edkins, S, van der Winkel, A, Levine, D, Sasieni, P, Bellenguez, C, Howarth, K, Freeman, C, Trudgill, N, Tucker, AT, Pirinen, M, Peppelenbosch, MP, van der Laan, LJW, Kuipers, EJ, Drenth, JPH, Peters, WH, Reynolds, JV, Kelleher, DP, McManus, R, Grabsch, H, Prenen, H, Bisschops, R, Krishnadath, K, Siersema, PD, van Baal, JWPM, Middleton, M, Petty, R, Gillies, R, Burch, N, Bhandari, P, Paterson, S, Edwards, C, Penman, I, Vaidya, K, Ang, Y, Murray, I, Patel, P, Ye, WM, Mullins, P, Wu, AH, Bird, NC, Dallal, H, Shaheen, NJ, Murray, LJ, Koss, K, Bernstein, L, Romero, Y, Hardie, LJ, Zhang, R, Winter, H, Corley, DA, Panter, S, Risch, HA, Reid, BJ, Sargeant, I, Gammon, MD, Smart, H, Dhar, A, McMurtry, H, Ali, H, Liu, G, Casson, AG, Chow, WH, Rutter, M, Tawil, A, Morris, D, Nwokolo, C, Isaacs, P, Rodgers, C, Ragunath, K, MacDonald, C, Haigh, C, Monk, D, Davies, G, Wajed, S, Johnston, D, Gibbons, M, Cullen, S, Church, N, Langley, R, Griffin, M, Alderson, D, Deloukas, P, Hunt, SE, Gray, E, Dronov, S, Potter, SC, Tashakkori-Ghanbaria, A, Anderson, M, Brooks, C, Blackwell, JM, Bramon, E, Brown, MA, Casas, JP, Corvin, A, Duncanson, A, Markus, HS, Mathew, CG, Palmer, CNA, Plomin, R, Rautanen, A, Sawcer, SJ, Trembath, RC, Viswanathan, AC, Wood, N, Trynka, G, Wijmenga, C, Cazier, JB, Atherfold, P, Nicholson, AM, Gellatly, NL, Glancy, D, Cooper, SC, Cunningham, D, Lind, T, Hapeshi, J, Ferry, D, Rathbone, B, Brown, J, Love, S, Attwood, S, MacGregor, S, Watson, P, Sanders, S, Ek, W, Harrison, RF, Moayyedi, P, de Caestecker, J, Barr, H, Stupka, E, Vaughan, TL, Peltonen, L, Spencer, CCA, Tomlinson, I, Donnelly, P, Jankowski, JAZ, Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus, NATURE GENETICS, 44, (10), 2012, p1131-+
Freeley M, O'Dowd F, Paul T, Kashanin D, Davies A, Kelleher D, Long A, L-plastin regulates polarization and migration in chemokine-stimulated human T lymphocytes., Journal of immunology (Baltimore, Md. : 1950), 188, (12), 2012, p6357-6370
Freeley, M., Kelleher, D. and Long, A. , Regulation of Protein Kinase C function by phosphorylation on conserved and non-conserved sites, Cellular Signalling, 23, (5), 2011, p753-762
White M, Mahon V, Grealy R, Doherty DG, Stordeur P, Kelleher DP, McManus R, Ryan T, Post-operative infection and sepsis in humans is associated with deficient gene expression of Yc cytokines and their apoptosis mediators., Critical Care (London, England), 15, (3), 2011, pR158
Marquez Ruiz JF, Kedziora K, Keogh B, Maguire J, Reilly M, Windle HJ, Kelleher D, Gilmer JF, A double prodrug system for colon targeting of benzenesulfonamide COX-2 inhibitors, Bioorganic & Medicinal Chemistry Letters, 21, (22), 2011, p6636-6640
Ruiz JF, Kedziora K, Keogh B, Maguire J, Reilly M, Windle H, Kelleher DP, Gilmer JF, A double prodrug system for colon targeting of benzenesulfonamide COX-2 inhibitors., Bioorganic & medicinal chemistry letters, 21, (22), 2011, p6636-40
di Iulio J, Ciuffi A, Fitzmaurice K, Kelleher D, Rotger M, Fellay J, Martinez R, Pulit S, Furrer H, Günthard HF, Battegay M, Bernasconi E, Schmid P, Hirschel B, Barnes E, Klenerman P, Telenti A, Rauch A, Estimating the net contribution of interleukin-28B variation to spontaneous hepatitis C virus clearance., Hepatology (Baltimore, Md.), 53, (5), 2011, p1446-1454
Petrovic D., Stamataki Z., Dempsey E., Golden-Mason L., Freeley M., Doherty D., Prichard D., Keogh C., Conroy J., Mitchell S., Volkov Y., McKeating J.A., O'Farrelly C., Kelleher D., Long A., Hepatitis C virus targets the Tcell secretory machinery as a mechanism of immune evasion, Hepatology, 53, (6), 2011, p1846 - 1853
Sharma R, Prichard D, Majer F, Byrne AM, Kelleher D, Long A, Gilmer JF, Ursodeoxycholic acid amides as novel glucocorticoid receptor modulators., Journal of medicinal chemistry, 54, (1), 2011, p122-130
Anthony Ryan, Mark Lynch, Sinead M. Smith, Sylvie Amu, Hendrik J. Nel, Claire E. McCoy, Jennifer K. Dowling, Eve Draper, Vincent O'Reilly, Ciara McCarthy, Julie O'Brien, Déirdre Ní Eidhin, Mary J. O'Connell, Brian Keogh, Charles O. Morton, Thomas R. Rogers, Padraic G. Fallon, Luke A. O'Neill, Dermot Kelleher, Christine E. Loscher , A Role for TLR4 in Clostridium difficile Infection and the Recognition of Surface Layer Proteins, PLoS Pathogens, 7, (6, e1002076), 2011
Mohamed BM, Verma NK, Prina-Mello A, Williams Y, Davies AM, Bakos G, Tormey L, Edwards C, Hanrahan J, Salvati A, Lynch I, Dawson K, Kelleher D, Volkov Y, Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity., Journal of nanobiotechnology, 9, 2011, p29
Fitzmaurice K, Petrovic D, Ramamurthy N, Simmons R, Merani S, Gaudieri S, Sims S, Dempsey E, Freitas E, Lea S, McKiernan S, Norris S, Long A, Kelleher D, Klenerman P, Molecular footprints reveal the impact of the protective HLA-A*03 allele in hepatitis C virus infection., Gut, 60, (11), 2011, p1563-71
Bashir Mustafa Mohamed, Navin Kumar Verma, Adriele Prina-Mello, Yvonne Williams, Anthony M Davies, Gabor Bakos, Laragh Tormey, Connla Edwards, John Hanrahan, Anna Salvati, Iseult Lynch, Kenneth Dawson, Dermot Kelleher, and Yuri Volkov, Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity, Journal of Nanobiotechnology, 9, 2011, p29-
Paszko E, Ehrhardt C, Senge MO, Kelleher DP, Reynolds JV, Nanodrug applications in photodynamic therapy., Photodiagnosis and photodynamic therapy, 8, (1), 2011, p14-29
Verma NK, Dempsey E, Freeley M, Botting CH, Long A, Kelleher D, Volkov Y, Analysis of dynamic tyrosine phosphoproteome in LFA-1 triggered migrating T-cells., Journal of Cellular Physiology, 226, (6), 2011, p1489-1498
Duggan S, Prichard D, Kirca M, Kelleher D, Inherited Syndromes Predisposing to Inflammation and GI Cancer., Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer, 185, 2011, p35-50
Merani S, Petrovic D, James I, Chopra A, Cooper D, Freitas E, Rauch A, di Iulio J, John M, Lucas M, Fitzmaurice K, McKiernan S, Norris S, Kelleher D, Klenerman P, Gaudieri S, Effect of immune pressure on hepatitis C virus evolution: insights from a single-source outbreak., Hepatology (Baltimore, Md.), 53, (2), 2011, p396-405
White M, Martin-Loeches I, Lawless MW, O'Dwyer MJ, Doherty DG, Young V, Kelleher D, McManus R, Ryan T, Hospital-acquired pneumonia after lung resection surgery is associated with characteristic cytokine gene expression., Chest, 139, (3), 2011, p626-32
Smith SM, Moran AP, Duggan SP, Ahmed SE, Mohamed AS, Windle HJ, O'Neill LA, Kelleher DP, Tribbles 3: a novel regulator of TLR2-mediated signaling in response to Helicobacter pylori lipopolysaccharide., Journal of immunology (Baltimore, Md. : 1950), 186, (4), 2011, p2462-2671
Carroll, TP, O'Connor, CA, Floyd, O, McPartlin, J, Kelleher, DP, O'Brien, G, Dimitrov, BD, Morris, VB, Taggart, CC, McElvaney, NG, The prevalence of alpha-1 antitrypsin deficiency in Ireland, RESPIRATORY RESEARCH, 12, (91), 2011
Ruiz JF, Kedziora K, Windle H, Kelleher DP, Gilmer JF, Investigation into drug release from colon-specific azoreductase-activated steroid prodrugs using in-vitro models., The Journal of pharmacy and pharmacology, 63, (6), 2011, p806-816
Freeley M, Bakos G, Davies A, Kelleher D, Long A, Dunican DJ, A high-content analysis toolbox permits dissection of diverse signaling pathways for T lymphocyte polarization., Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening, 15, (5), 2010, p541 - 555
Dubois PCA, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GA, Ádány R, Aromaa A, Bardella MT, van den Berg LH, Bockett NA, de la Concha EG, Dema B, Fehrmann RS, Fernández-Arquero M, Fiatal S, Grandone E, Green PM, Groen HJ, Gwilliam R, Houwen RH, Hunt SE, Kaukinen K, Kelleher D, Korponay-Szabo I, Kurppa K, MacMathuna P, Mäki M, Mazzilli MC, McCann OT, Mearin ML, Mein CA, Mirza MM, Mistry V, Mora B, Morley KI, Mulder CJ, Murray JA, Núñez C, Oosterom E, Ophoff RA, Polanco I, Peltonen L, Platteel M, Rybak A, Salomaa V, Schweizer JJ, Sperandeo MP, Tack GJ, Turner G, Veldink JH, Verbeek , Weersma RK, Wolters VM, Urcelay E, Cukrowska B, Greco L, Neuhausen SL, McManus R, Barisani D, Deloukas P, Barrett JC, Saavalainen P, Wijmenga C, van Heel DA, Multiple common variants for celiac disease influencing immune gene expression, Nature Genetics, 42, (4), 2010, p295 - 302
White M, Lawless MW, O'Dwyer MJ, Grealy R, O'Connell B, Stordeur P, Kelleher D, McManus R*, Ryan T*, Transforming Growth Factor beta-1 and Interleukin-17 gene transcription in peripheral blood mononuclear cells and the human response to infection, Cytokine, 50, 2010, p322 - 327
Brophy K*, Ryan AW*, Turner G, Trimble V, Patel KD, O'Morain C, Kennedy NP, Egan B, Close E, Lawlor G, MacMathuna P, Stevens FM, Abuzakouk M, Feighery C, Kelleher D, McManus R, Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study, BMC Medical Genetics, 11, (76), 2010
Duggan SP, Behan FM, Kirca M, Smith S, Reynolds JV, Long A, Kelleher D, An integrative genomic approach in oesophageal cells identifies TRB3 as a bile acid responsive gene, down regulated in Barrett's oesophagus, which regulates NF-kB activation and cytokine levels., Carcinogenesis, 5, 2010, p936 - 945
Ruchika Sharma, Ferenc Majer, Vijaya Kumar Peta, Jun Wang, Ray Keaveney, Dermot Kelleher, Aideen Long and John F. Gilmer, Bile acid toxicity structure activity relationships: Correlations between cell viability and lipophilicity in a panel of new and known bile acids using an esophageal cell line (HET-1A), Bioorganic & Medicinal Chemistry, 18, (18), 2010, p6886-6895
Byrne AM, Foran E, Sharma R, Davies A, Mahon C, O'Sullivan J, O'Donoghue D, Kelleher D, Long A, Bile acids modulate the Golgi membrane fission process via a protein kinase Ceta and protein kinase D-dependent pathway in colonic epithelial cells., Carcinogenesis, 31, (4), 2010, p737-744
Sharma R, Majer F, Peta VK, Wang J, Keaveney R, Kelleher D, Long A, Gilmer JF, Bile acid toxicity structure-activity relationships: correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A)., Bioorganic & medicinal chemistry, 18, (18), 2010, p6886-95
White M, Lawless MW, O'Dwyer MJ, Grealy R, Connell BO, Stordeur P, Kelleher D, McManus R, Ryan T, Transforming growth factor beta-1 and interleukin-17 gene transcription in peripheral blood mononuclear cells and the human response to infection., Cytokine, 50, (3), 2010, p322-7
Dubois PC, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GA, Adány R, Aromaa A, Bardella MT, van den Berg LH, Bockett NA, de la Concha EG, Dema B, Fehrmann RS, Fernández-Arquero M, Fiatal S, Grandone E, Green PM, Groen HJ, Gwilliam R, Houwen RH, Hunt SE, Kaukinen K, Kelleher D, Korponay-Szabo I, Kurppa K, MacMathuna P, Mäki M, Mazzilli MC, McCann OT, Mearin ML, Mein CA, Mirza MM, Mistry V, Mora B, Morley KI, Mulder CJ, Murray JA, Núñez C, Oosterom E, Ophoff RA, Polanco I, Peltonen L, Platteel M, Rybak A, Salomaa V, Schweizer JJ, Sperandeo MP, Tack GJ, Turner G, Veldink JH, Verbeek WH, Weersma RK, Wolters VM, Urcelay E, Cukrowska B, Greco L, Neuhausen SL, McManus R, Barisani D, Deloukas P, Barrett JC, Saavalainen P, Wijmenga C, van Heel DA, Multiple common variants for celiac disease influencing immune gene expression., Nature genetics, 42, (4), 2010, p295-302
Windle HJ, Brown PA, Kelleher DP, Proteomics of bacterial pathogenicity: therapeutic implications., Proteomics. Clinical applications, 4, (2), 2010, p215-27
Kozak K, Bakos G, Hoff A, Bennett E, Dunican D, Davies A, Kelleher D, Long A, Csucs G, Workflow-based software environment for large-scale biological experiments., Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening, 15, (7), 2010, p892-9
Patel KD, Murphy RT, White M, Gasparrow D, Kelleher DP, Ryan T, McManus R, Ryan AW., Interleukin 17: an unlikely marker of acute coronary syndrome?, Atherosclerosis, 205, (1), 2009, p33 - 34
Looby E, Abdel-Latif MM, Athié-Morales V, Duggan S, Long A, Kelleher D., Deoxycholate induces COX-2 expression via Erk1/2 - p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells, BMC Cancer, 9, (190), 2009
Williams Y., Sukhanova A., Nowostawska M., Davies A.M., Mitchell S., Oleinikov V., Gun'ko Y., Nabiev I., Kelleher D., Volkov Y., Probing cell-type-specific intracellular nanoscale carriers using size-tuned quantum dots, Small, 5, (22), 2009, p2581 - 2588
Patel KD, Duggan SP, Currid CA, Gallagher WM, McManus R, Kelleher D, Murphy RT, Ryan AW., High sensitivity cytokine detection in acute coronary syndrome reveals up-regulation of Interferon Gamma and Interleukin-10 post myocardial infarction., Clinical Immunology, 133, (2), 2009, p251 - 256
Ruiz JF, Radics G, Windle H, Serra HO, Simplicio AL, Kedziora K, Fallon PG, Kelleher DP, Gilmer JF., Design, synthesis and pharmacological effects of a cyclization-activated steroid prodrug for colon targeting in inflammatory bowel disease., J Med Chem, 52, (10), 2009, p3205 - 3211
Babar M, Abdel-Latif MM, Ravi N, Murphy A, Byrne PJ, Kelleher D, Reynolds JV., Pilot translational study of dietary vitamin C supplementation in Barrett's esophagus., Dis Esophagus, 23, (3), 2009
Birmingham A, Selfors LM, Forster T, Wrobel D, Kennedy CJ, Shanks E, Santoyo-Lopez J, Dunican DJ, Long A, Kelleher D, Smith Q, Beijersbergen RL, Ghazal P, Shamu CE, Statistical methods for analysis of high-throughput RNA interference screens, Nat Methods, 6, (8), 2009, p569 - 575
Williams Y, Sukhanova A, Nowostawska M, Davies AM, Mitchell S, Oleinikov V, Gun'ko Y, Nabiev I, Kelleher D, Volkov Y., Probing cell-type-specific intracellular nanoscale barriers using size-tuned quantum dots., Small, 5, (22), 2009, p2581 - 2588
Dazert E, Neumann-Haefelin C, Bressanelli S, Fitzmaurice K, Kort J, Timm J, McKiernan S, Kelleher D, Gruener N, Tavis JE, Rosen HR, Shaw J, Bowness P, Blum HE, Klenerman P, Bartenschlager R, Thimme R., Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response, The Journal of Clinical Investigation, 119, (2), 2009, p376 - 386
Ruiz Marquez JF, Radics G, Windle H, Serra HO, Simplicio AL, Kedziora K, Fallon PG, Kelleher DP, Gilmer GF, Design, Synthesis, and Pharmacological Effects of a Cyclization-activated Steroid Prodrug for Colon Targeting in Inflammatory Bowel Disease, Journal of Medicinal Chemistry, 52, (10), 2009, p3205 - 3211
Verma NK, Dourlat J, Davies AM, Long A, Liu WQ, Garbay C, Kelleher D, Volkov Y. , STAT3-stathmin interactions control microtubule dynamics in migrating T-cells., J Biol Chem, 284, (18), 2009, p12349 - 12362
Mankan, A.K., Lawless, M.W., Gray, S.G., Kelleher, D., McManus, R., NF-κB regulation: The nuclear response , Journal of Cellular and Molecular Medicine , 13, (4), 2009, p631-643
Abdel-Latif MM, Windle HJ, Davies A, Volkov Y, Kelleher D., Inflammation and esophageal carcinogenesis., Curr Opin Pharmacol, 9, (4), 2009, p396 - 404
Verma NK, Dempsey E, Conroy J, Olwell P, Mcelligott AM, Davies AM, Kelleher D, Butini S, Campiani G, Williams DC, Zisterer DM, Lawler M, Volkov Y., A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin., Journal of Molecular Medicine, 86, (4), 2008, p457-469
Conroy J, Byrne SJ, Gun'ko YK, Rakovich YP, Donegan JF, Davies A, Kelleher D, Volkov Y., CdTe Nanoparticles Display Tropism to Core Histones and Histone-Rich Cell Organelles, Small, 4, (11), 2008, 2006-2015
O'Dwyer MJ, Mankan AK, Stordeur P, White W, Lawless MW, O'Connell B, Kelleher D, McManus R*, Ryan T*. , The human response to infection is associated with distinct patterns of interleukin 23 and interleukin 27 expression, Intensive Care Medicine, 34, (4), 2008, p683-691
O'Dwyer MJ, Mankan AK, Stordeur P, White W, Lawless MW, O'Connell B, Kelleher D, McManus R*, Ryan T* , Variability in IL-23 and IL-27 gene expression may determine patient response to a septic insult, Intensive Care Medicine, 34, (4), 2008, p683 - 691
Hunt KA, Zhernakova A, Turner G, Heap GA, Franke L, Bruinenberg M, Romanos J, Dinesen LC, Ryan AW, Panesar D, Gwilliam R,Takeuchi F, McLaren WM, Holmes GK, Howdle PD, Walters JR, Sanders DS, Playford RJ, Trynka G, Mulder CJ, Mearin ML,Verbeek WH, Trimble V, Stevens FM, O'Morain C, Kennedy NP, Kelleher D, Pennington DJ, Strachan DP, McArdle WL, Mein CA,Wapenaar MC, Deloukas P, McGinnis R, McManus R*, Wijmenga C*, van Heel DA*., Newly identified genetic risk variants for celiac disease related to the immune response., Nature Genetics, 40, 2008, p395-402
Duggan E, O'Dwyer M, Caraher E, Diviney D, McGovern E, Kelleher D, McManus R, Ryan T, Coagulopathy After Cardiac Surgery May Be Influenced by a Functional Plasminogen Activator Inhibitor Polymorphism, Anesthesia & Analgesia , 104, (6), 2007, p1343 - 1347
Azim K, McManus R, Brophy K, Ryan A, Kelleher D, Reynolds JV, Genetic Polymorphisms and the Risk of Infection Following Esophagectomy , Annals of Surgery, 246, (1), 2007, p122 - 128
van Heel DA, Franke L, Hunt KA, Gwilliam R, Zhernakova A, Inouye M, Wapenaar MC, Barnardo MC, Bethel G, Holmes GK, Feighery C, Jewell D, Kelleher D, Kumar P, Travis S, Walters JR, Sanders DS, Howdle P, Swift J, Playford RJ, McLaren WM, Mearin ML, Mulder CJ, McManus R, McGinnis R, Cardon LR, , A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21., Nature Genetics, 39, (7), 2007, p827 - 829
Igor Nabiev, Siobhan Mitchell, Anthony Davies, Yvonne Williams, Dermot Kelleher, Richard Moore, Yurii K. Gun'ko, Stephen Byrne, Yury P. Rakovich, John F. Donegan, Alyona Sukhanova, Jennifer Conroy, David Cottell, Nikolai Gaponik, Andrey Rogach and Yuri Volkov, Non-Functionalized Nanocrystals Can Exploit a Cell's Active Transport Machinery Delivering Them to Specific Nuclear and Cytoplasmic Compartments, NanoLetters , 7, 2007, p3452-3461
Goulding C, O'Brien C, Egan H, Hegarty JE, McDonald G, O'Farrelly C, White B, Kelleher D, Norris S, The impact of inherited prothrombotic risk factors on individuals chronically infected with hepatitis C virus from a single source., Journal of Viral Hepatology, 14, (4), 2007, p255 - 259
Windle HJ, Kelleher D, Crabtree JE, Childhood Helicobacter pylori infection and growth impairment in developing countries: a vicious cycle?, Paediatrics, 119, (3), 2007, pe754 - e759
Nabiev, I, Mitchell, S, Davies, A, Williams, Y, Kelleher, D, Moore, R, Gun'ko, YK, Byrne, S, Rakovich, YP, Donegan, JF, Sukhanova, A, Conroy, J, Cottell, D, Gaponik, N, Rogach, A, Volkov, Y, Nonfunctionalized nanocrystals can exploit a cell's active transport machinery delivering them to specific nuclear and cytoplasmic compartments, Nano Letters, 7, (11), 2007, p3452-3461
Smyth CM, McKiernan SM, Hagan R, Pilkington R, O'Regan M, Lawlor E, Kelleher D., Chronic hepatitis C infection and sicca syndrome: a clear association with HLA DQB1*02, European Journal of Gastroenterology and Hepatology, 19, (6), 2007, p493 - 498
Ryan AW, Mapp J, Moyna S, Mattiangeli V, Kelleher D, Bradley DG, McManus R, Levels of inter-population differentiation among different functional classes of immunologically important genes, Genes and Immunity, 7, (2), 2006, p179 - 183
O'Dwyer MJ, Mankan AK, Stordeur P, O'Connell B, Duggan E, White M, Kelleher DP, McManus R, Ryan T., The occurrence of severe sepsis and septic shock are related to distinct patterns of cytokine gene expression., Shock, 26, (6), 2006, p544 - 550
Neumann-Haefelin C, McKiernan S, Ward S, Viazov S, Spangenberg HC, Killinger T, Baumert TF, Nazarova N, Sheridan I, Pybus O, von Weizsacker F, Roggendorf M, Kelleher D, Klenerman P, Blum HE, Thimme R, Dominant influence of an HLA-B27 restricted CD8+ T cell response in mediating HCV clearance and evolution, Hepatology, 22, (43(3)), 2006, p563 - 572
Duggan SP, Gallagher WM, Fox EJ, Abdel-Latif MM, Reynolds JV, Kelleher D., Low pH results in co-ordinate regulation of gene expression in oesophageal cells, Carcinogenesis, 27, (2), 2006, p319 - 327
Abdel-Latif MM, Windle H, Terres A, NiEidhin DN, Kelleher D, Reynolds JV, Helicobacter pylori extract induces nuclear factor-kappa B, activator protein-1, and cyclooxygenase-2 in esophageal epithelial cells, Journal of Gastrointestinal Surgery, 10, (4), 2006, p551 - 562
Duggan E, Caraher E, Gately C, O'Dwyer M, McGovern E, Kelleher D, McManus R, Ryan T, Tumour necrosis factor alpha and Interleukin10 gene expression after cardiac surgery: The protective role of Interleukin 10, Critical Care Medicine , 34, (8), 2006, p2134 - 2139
Duggan E, Caraher E, Gately K, O'Dwyer M, McGovern E, Kelleher D, McManus R, Ryan T., Tomour necrosis factor-alpha and interleukin-10 gene expression in peripheral blood mononuclear cells after cardiac surgery, Critical Care Medicine, 34, (8), 2006, p2134 - 2139
Mechanisms of steroid action and resistance in inflammatory bowel disease in, editor(s)DP Jewell, J-F Colombel, AS Pena, A Tromm, BF Warren , Colitis: Diagnosis and Therapeutic Strategies, Netherlands, Springer, 2006, pp87 - 97, [D Kelleher, R McManus]
Ryan R, Thornton J, Dugan E, McGovern E, O'Dwyer MJ, Ryan AW, Kelleher D, McManus R, Ryan T, Gene polymorphism and requirement for vasopressor infusion after cardiac surgery, Annals of Thoracic Surgery, 82, (3), 2006, p895 - 901
Deirdre Ni Eidhin, Anthony W Ryan, Rachael M Doyle, J Bernard Walsh, Dermot Kelleher, Sequence and phylogenetic analysis of the gene for surface layer protein, slpA, from 14 PCR ribotypes of Clostridium difficile, Journal of Medical Microbiology, 55, (1), 2006, p69 - 83
Shah SA, Volkov Y, Arfin Q, Abdel-Latif MM, Kelleher D, Ursodeoxycholic acid inhibits interleukin beta 1 and deoxycholic acid-induced activation of NF-kappaB and AP-1 in human colon cancer cells, International Journal of Cancer, 1, (118(3)), 2006, p532 - 539
Ryan R*, Thornton J*, Duggan E, McGovern E, O'Dwyer MJ, Ryan AW, Kelleher D, McManus R, Ryan T, Gene polymorphism and requirement for vasopressor infusion after cardiac surgery, Annals of Thoracic Surgery, 82, (3), 2006, p895 - 901
Mechanisms of steroid action and resistance in inflammatory bowel disease. in, editor(s)Jewell DP, Colombel, JF, Pena AS, Tromm A, Warren BS , Colitis: Diagnosis and Therapeutic Strategies, Falk Symposia, Kluwer Academic Publishers, 2006, pp87-97 , [Kelleher D, McManus R.]
El Din El Homasany B.S., Volkov Y., Takahashi M., Ono Y., Keryer G., Delouvée A., Looby E., Long A., Kelleher D., The scaffolding protein CG-NAP/AKAP450 is a critical integrating component of the LFA-1-induced signaling complex in migratory T cells, Journal of Immunology, 175, (12), 2006, p7811 - 7818
Brophy K, Ryan AW, Thornton JM, Daly JS, McLoughlin R, O' Morain C, Abuzakouk M, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R, Haplotypes in the CTLA4 region are associated with coeliac disease in the Irish population., Genes and Immunity, 7, (1), 2006, p19 - 26
Volkov Y, Long A, Freeley M, Golden-Mason L, O'Farrelly C, Murphy A, Kelleher D, The hepatitis C envelope 2 protein inhibits LFA-1 transduced protein kinase C signalling for T lymphocyte migration, Gastroenterology, 130, (2), 2006, p482 - 492
Levine RA, Sanderson SO, Ploutz-Snyder R, Murray F, Kay E, Hegarty J, Nolan N, Kelleher D, McDonald G, O'Keane JC, Drowe J, Assessment of fibrosis progression in untreated Irish women with chronic hepatitis C contracted from immunoglobulin anti-D, Clinical Gastroenterology and Hepatology, 4, (10), 2006, p1271 - 1277
Abuzakouk M, Fitzgerald AP, McLoughlin RM, O'Morain C, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R, Haplotypes in the CTLA4 region are associated with coeliac disease in the Irish population, Genes Immun, 7, (1), 2006, p19 - 26
O'Dwyer MJ, Mankan AK, Stordeur P, O'Connell B, Duggan E, White M, Kelleher DP, McManus R, Ryan T, The occurrence of severe sepsis is related to distinct patterns of cytokine gene expression, Shock, 26, (6), 2006, p544 - 550
Shah SA, Mahmud N, Mftah M, Roche HM, Kelleher D, Chronic but not acute conjugated linoleic acid treatment inhibits deoxycholic acid-induced protein kinase C and nuclear factor-kappaB activation in human colorectal cancer cells, European Journal of Cancer Prevention , 15, (2), 2006, p125 - 133
O'Dwyer MJ, Dempsey F, Crowley V, Kelleher DP, McManus R, Ryan T., Septic shock is correlated with asymmetrical dimethyl arginine levels, which may be influenced by a polymorphism in the dimethylarginine dimethylaminohydrolase II gene: a prospective observational study., Critical Care, 10, (5), 2006, pR139
Volkov Y, Long A, Freeley M, Golden-Mason L, O'Farrelly C, Murphy A, Kelleher D, The hepatitis C envelope 2 protein inhibits LFA-1-tranduced protein kinase C signalling for T lymphocyte migration, Gastroenterology, 130, (2), 2006, p482 - 492
Foran E, McWilliam P, Kelleher D, Croke DT, Long A, The leukocyte protein L-plastin induces proliferation, invasion and loss of E-cardherin expression in colon cancer cells, International Journal of Cancer, 118, (8), 2006, p2098 - 2104
O'Dwyer MJ, Dempsey F, Crowley V, Kelleher D, McManus R, Ryan T., Septic shock correlates with ADMA levels which may be influenced by a polymorphism in DDAH II: a prospective observational study, Critical Care, 10, (5), 2006, pR139 article number
Dring MM, Goulding CA, Trimble VI, Keegan D, Ryan AW, Brophy KM, Smyth CM, Keeling PWN, O'Donoghue D, O'Sullivan M, O'Morain C, Mahmud N, Wikström A-C, Kelleher D, McManus R., The Pregnane X Receptor Locus is Associated with susceptibility to inflammatory bowel disease., Gastroenterology, 130, (2), 2006, p341 - 348
K Brophy, AW Ryan, JM Thornton, M Abuzakouk, AP Fitzgerald, RM McLoughlin, C O'Morain, NP Kennedy, FM Stevens, C Feighery, D Kelleher, R McManus, Haplotypes in the CTLA4 region are associated with coeliac disease in the Irish population, Genes and Immunity, 7, (1), 2006, p19 - 26
Megan M Dring, Carol A Goulding, Valerie I Trimble, Denise Keegan, Anthony W Ryan, Karen M Brophy, Claire M Smyth, P. W. Napoleon Keeling, Diarmuid O'Donoghue, Maria O'Sullivan, Colm O'Morain, Nasir Mahmud, Ann-CharlotteWikström, Dermot Kelleher, Ross McManus , The Pregnane X Receptor Locus is Associated with susceptibility to inflammatory bowel disease, 2006, p341 - 348
J Cosgrave, JB Foley, R Kelly, E McGovern, K Bennett, V Young, M Tolan, P Crean, D Kelleher, MJ Walsh, Perioperative serum inflammatory response and the development of atrial fibrilation after coronary artery bypass surgery, Heart, 91, 2005, p1475 - 1476
Murphy AM, Sheils OM, McDonald GS, Kelleher DP., Detection of a Tyrosine Phosphatase LAR on Intestinal Epithelial Cells and Intraepithelial Lymphocytes in the Human Duodenum., Mediators of Inflammation, 1, 2005, p23 - 30
D O'Toole, MM Abdel-Latif, A Long, HJ Windle, AM Murphy, A Bowie, LA O'Neill, DG Weir, D Kelleher, Low pH and Helicobacter pylori increase nuclear factor kappa B binding in gastric epithelial cells: a common pathway for epithelial cell injury?, Journal of Cellular Biochemistry, 96, (3), 2005, p589 - 598
Ryan AW, Thornton JM, Brophy K, Daly JS, McLoughlin RM, O' Morain C, Abuzakouk M, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R., Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1., Tissue Antigens, 65, (2), 2005, p150 - 155
O'Toole D, Abde;-Latif AM, Long A, Windle HJ, Murphy AM, Bowie A, O'Neill LA, Weir DG, Kelleher D, Low pH and Helicobacter pylori increase nuclear factor kappa B binding in gastric epithelial cells: a common pathway for epithelial cell injury?, Journal of Cellular Biochemistry, 96, (3), 2005, p589 - 588
H. J. Windle, Y. S. Ang, V. A. Morales, R. McManus and D. Kelleher, Human peripheral and gastric lymphocyte responses to Helicobacter pylori NapA and AphC differ in infected and uninfected individuals, Gut, 54, (1), 2005, p25-32
Windle HJ*, Ang YS*, Athie Morales V, McManus R*, Kelleher DP , Human peripheral and gastric lymphocyte responses to Helicobacter pylori NapA and AphC differ in infected and uninfected individuals, Gut, 54, (1), 2005, p25 - 32
Christine E Loscher, Eve Draper, Olive Leavy, Dermot Kelleher, Kingston HG Mills, Helen M Roche, Conjugated linoleic acid suppresses NF-kappaB activation and IL-12 production in dendritic cells through ERK-Mediated IL-10 induction, The Journal of Immunology, 175, 2005, p4990 - 4998
Salah B., Homasany El. Din. El., Volkov Y., Takahashi M., Ono Y., Keryer G., Delouvee A., Looby E., Long A., Kelleher D., The scaffolding protein CG-NAP/AKAP450 is a critical integrating component of LFA-1 induced signaling complex in migratory T cells, The Journal of Immunology, 175, 2005, p7811 - 7818
Joseph F Murphy, Frances Lennon, Christopher Steele, Dermot Kelleher, Desmond Fitzgerald, Aideen Long, Engagement of CD44 Modulates cyclooxygenase induction, VEGF generation, and cell proliferation in human vascular endothelial cells, The FASEB Journal, 19, (3), 2005, p446-448
Syed Shah, Eileen Looby, Yuri Volkov, Aideen Long, Sermot Kelleher, Ursodeoxycholic acid inhibits translocation of protein kinase C in human colonic cancer cell lines, European Journal of Cancer, 41, (14), 2005, p2160 - 2169
B Mee, D Kelleher, J Frias, R Malone, KF Tipton, GT Henehan, HJ Windle, Characterization of cinnamyl alcohol dehydrogenase of Helicobacter pylori. An aldehyde dismutating enzyme, FEBS J, 272, (5), 2005, p1255 - 1264
M Freeley, Y Volkov, D Kelleher, A Long, Stimulus-induced phosphorylation of PKC theta at the C-terminal hydrophobic-motif in human T lymphocytes, Biochem Biophys Res Commun, 334, (2), 2005, p619 - 630
Elena Papinutto, Henry J Windle, Laura Centron, Roberto Battistutta, Dermot Kelleher, Giuseppe Zanotti, Crystal structure of alkyl hydroperoxide-reductase (AhpC) from Helicobacter pylori, Biochimica et Biophysica Acta, 1, (1753(2)), 2005, p240 - 246
C Goulding, A Murphy, G MacDonald, S Barrett, J Crowe, J Hegarty, S McKiernan, D Kelleher, The CCR5-delta32 mutation: impact on disease outcome in individuals with hepatitis C infection from a single source, Gut, 54, (8), 2005, p1157 - 1161
Mohamed MM Abdel-Latif, Henry J Windle, Basma S El Homasany, Kamal Sabra, Dermot Kelleher, Caffeic acid phenethyl ester modulates Helicobacter pylori-induced nuclear factor-kappa B and activator protein-1 expression in gastric epithelial cells, British Journal of Pharmacology, 146, (8), 2005, p1139 - 1147
Loscher CE, Draper E, Leavy O, Kelleher D, Mills KHG & Roche HM , Conjugated linoleic acid suppresses NF-kappa B activation and IL-12 production in dendritic cells through ERK-mediated IL-10 induction, Journal of Immunology, 175, (8), 2005, p4990 - 4998
Loscher, CL Leavy, O. Kelleher, D, *Mills, K.H.G and *Roche, H.M. *Equal contribution, Conjugated linoleic acid suppresses NFkB activation and IL-12 production in dendritic cells through ERK-mediated IL-10 induction., Journal of Immunology, 175, (8), 2005, p4990 - 4998
MMM Abdel-Latif, AA Raouf, K Sabra, D Kelleher, JV Reynolds, Vitamin C Enhances Chemosensitization of Esophageal Cancer Cells in Vitro, Journal of Chemotherapy, 17, (4), 2005, p52 - ??
JM O'Riordan, MM Abdel-Latif, N Ravi, D McNamara, PJ Byrne, G McDonald, PW Keeling, D Kelleher, JV Reynolds, Proinflammatory cytokine and nuclear factor kappa-B expression along the inflammation-metaplasia-dysplasia-adenocarcinoma sequence in the esophagus, American Journal of Gastroenterology, 100, (6), 2005, p1257 - 1264
AP Nugent, HM Roche, EJ Noone, A Long, DK Kelleher, MJ Gibney, The effects of conjugated linoleic acid supplementation on immune function in healthy volunteers, European Journal of Clinical Nutrition, 59, 2005, p742 - 750
AW Ryan, JM Thornton, K Brophy, JS Daly, RM McLoughlin, C O'Morain, M Abuzakouk, NP Kennedy, FM Stevens, C Feighery, D Kelleher, R McManus, Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1, Tissue Antigens, 65, (2), 2005, p150 - 155
Goulding C, McManus R, Murphy A, MacDonald GS, Barrett S, Crowe J, Hegarty J, McKiernan S, Kelleher D., The CCR5-delta32 Mutation- Impact on disease outcome in individuals with hepatitis C infection from a single source, Gut, 54, (8), 2005, p1157 - 1161
Fanning A., Volkov Y., Freeley M., Kelleher D., Long A., CD44 cross-linking induces protein kinase C-regulated migration of human T lymphocytes, Journal of International Immunology, 17, (4), 2005, p449 - 458
MMM Abdel-Latif, JM O'Riordan, N Ravi, D Kelleher, JV Reynolds, Activated nuclear factor-kappa B and cytokine profiles in the esophagus parallel tumor regression following neoadjuvant chemoradiotherapy, Diseases of the Esophagus, 18, 2005, p246 - 252
J Barry, M Bourke, M Buckley, B Coughlan, D Crowley, W Cullen, S Dooley, S Keating, D Kelleher, J Moloney, F Murray, PA McCormick, P MacMathuna, J O'Connor, J O'Grady, C O'Sullivan, P O'Sullivan, C Quinn, B Smyth, B Sweeney, Dublin Area Hepatitis C Initiative Group. Hepatitis C among drug users: consensus guidelines on management in general practice, Irish Journal of Medical Science, 173, (3), 2004, p145 - 150
S. Weldon, S. Mitchell, D. Kelleher, M. J. Gibney and H. M. Roche, Conjugated linoleic acid and atherosclerosis: no effect on molecular markers of cholesterol homeostasis in THP-1 macrophages, Atherosclerosis, 174, (2), 2004, p261-73
M. Hennessy, S. Clarke, J. P. Spiers, D. Kelleher, F. Mulcahy, P. Hoggard, D. Back and M. Barry, Intracellular accumulation of nelfinavir and its relationship to P-glycoprotein expression and function in HIV-infected patients, Antiviral therapy, 9, (1), 2004, p115-22
M. M. Abdel-Latif, H. J. Windle, K. A. Fitzgerald, Y. S. Ang, D. N. Eidhin, M. Li-Weber, K. Sabra and D. Kelleher, Helicobacter pylori activates the early growth response 1 protein in gastric epithelial cells, Infection and immunity, 72, (6), 2004, p3549-60
Ryan AW, Thornton JM, Brophy K, Daly JS, O' Morain C, McLoughlin RM, Kennedy NP, Abuzakouk M, Stevens FM, Feighery C, Kelleher D, McManus R. , Haplotype variation at the IBD5 locus (5q31) in coeliac disease in the Irish population. , Tissue Antigens, 64, (2), 2004, p195 - 198
Arnott IDR, Nimmo ER, Drummond HE, Fennell J, Smith BR, MacKinlay E, Morecroft J, Anderson N, O'Sullivan M, O'Morain C, Kelleher D, McManus R, Satsangi J., NOD2/CARD15, TLR4 and CD14 Mutations in Scottish and Irish Patients with Crohn's disease: Evidence for Genetic Heterogeneity within Europe., Genes and Immunity, 5, (5), 2004, p417 - 425
A. W. Ryan, J. M. Thornton, K. Brophy, J. S. Daly, C. O'Morain, R. M. McLoughlin, N. P. Kennedy, M. Abuzakouk, F. M. Stevens, C. Feighery, D. Kelleher and R. McManus, Haplotype variation at the IBD5/SLC22A4 locus (5q31) in coeliac disease in the Irish population, Tissue antigens, 64, (2), 2004, p195-8
I. D. Arnott, E. R. Nimmo, H. E. Drummond, J. Fennell, B. R. Smith, E. MacKinlay, J. Morecroft, N. Anderson, D. Kelleher, M. O'Sullivan, R. McManus and J. Satsangi, NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: evidence for genetic heterogeneity within Europe?, Genes and immunity, 5, (5), 2004, p417-25
Long, A., Mitchell, S., Kashanin, D., Williams, V., Mello, A.P., Shvets, I., Kelleher, D., Volkov, Y., A Multidisciplinary Approach to the Study of T Cell Migration, Annals of the New York Academy of Sciences, 1028, 2004, p313 - 319
M. M. Abdel-Latif, J. O'Riordan, H. J. Windle, E. Carton, N. Ravi, D. Kelleher and J. V. Reynolds, NF-kappaB Activation in Esophageal Adenocarcinoma: Relationship to Barrett's Metaplasia, Survival, and Response to Neoadjuvant Chemoradiotherapy, Annals of Surgery, 239, (4), 2004, p491-500
S. M. McKiernan, R. Hagan, M. Curry, G. S. McDonald, A. Kelly, N. Nolan, A. Walsh, J. Hegarty, E. Lawlor and D. Kelleher, Distinct MHC class I and II alleles are associated with hepatitis C viral clearance, originating from a single source, Hepatology (Baltimore, Md), 40, (1), 2004, p108-14
A. Long, S. Mitchell, D. Kashanin, V. Williams, A. Prina Mello, I. Shvets, D. Kelleher and Y. Volkov, A multidisciplinary approach to the study of T cell migration, Annals of the New York Academy of Sciences, 1028, 2004, p313-9
Kelleher D, Farrell R, McManus R., Pharmacogenetics of inflammatory bowel disease., Novartis Foundation Symposium - Inflammatory Bowel Disease: Crossroads of Microbes, Epithelium and Immune Systems, edited by Derek Chadwick, Jamie Goode , 263, Novartis Foundation, 2004, pp41-53
A. P. Mello, Y. Volkov, D. Kelleher and P. J. Prendergast, Comparative locomotory behavior of T lymphocytes versus T lymphoma cells on flat and grooved surfaces, Annals of biomedical engineering, 31, (9), 2003, p1106-13
McManus R, Kelleher D , Celiac disease - the villain unmasked? (Invited commentary)., New England Journal of Medicine , 348, (25), 2003, p2573-2574
R. McManus and D. Kelleher, Celiac disease--the villain unmasked?, The New England journal of medicine, 348, (25), 2003, p2573-4
A. M. Terres, H. J. Windle, E. Ardini and D. P. Kelleher, Soluble extracts from Helicobacter pylori induce dome formation in polarized intestinal epithelial monolayers in a laminin-dependent manner, Infection and immunity, 71, (7), 2003, p4067-78
Ryan BM, Lefort L, McManus R, Daly J, Keeling PW, Weir DG, Kelleher D, A prospective study of circulating mutant KRAS2 in the serum of patients with colorectal neoplasia: strong prognostic indicator in postoperative follow up, Gut, 52, (1), 2003, p101-108
R. J. Farrell and D. Kelleher, Glucocorticoid resistance in inflammatory bowel disease, The Journal of Endocrinology, 178, (3), 2003, p339-46
Prina-Mello A., Volkov Y., Kelleher D., Prendergast P.J., Comparative locomotory behaviour of T Lymphocytes versus T Lymphoma cells on flat and grooved surfaces., Annals of Biomedical Engineering. , 31, 2003, p1106 - 1113
F. Khosa, J. G. McNulty, N. Hickey, P. O'Brien, A. Tobin, N. Noonan, B. Ryan, P. W. Keeling, D. P. Kelleher and G. S. McDonald, Transvenous liver biopsy via the femoral vein, Clinical radiology, 58, (6), 2003, p487-91
M. Hennessy, S. Clarke, J. P. Spiers, F. Mulcahy, D. Kelleher, E. Meadon, B. Maher, C. Bergin, S. Khoo, J. Tjia, P. Hoggard, D. Back and M. Barry, Intracellular indinavir pharmacokinetics in HIV-infected patients: comparison with plasma pharmacokinetics, Antiviral therapy, 8, (3), 2003, p191-8
M. Hennessy, D. Kelleher, J. P. Spiers, M. Barry, P. Kavanagh, D. Back, F. Mulcahy and J. Feely, St Johns wort increases expression of P-glycoprotein: implications for drug interactions, British Journal of Clinical Pharmacology, 53, (1), 2002, p75-82
C. Smyth, D. Kelleher and P. W. Keeling, Hepatic manifestations of gastrointestinal diseases. Inflammatory bowel disease, celiac disease, and Whipple's disease, Clinics in liver disease, 6, (4), 2002, p1013-32
HENNESSY, M, KELLEHER, D, SPIERS, JP, BARRY, M, KAVANAGH, P, BACK, D, MULCAHY, F, FEELY, J, ST JOHN'S WORT INCREASES EXPRESSION OF P-GLYCOPROTEIN: IMPLICATIONS FOR DRUG INTERACTIONS, BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 53, 2002, p75 - 82
Y. S. Ang, N. Macaleenan, N. Mahmud, P. W. Keeling, D. P. Kelleher and D. G. Weir, The yield of colonoscopy in average-risk patients with non-specific colonic symptoms, European journal of gastroenterology & hepatology, 14, (10), 2002, p1073-7
DUFFY, M, SALEMI, M, SHEEHY, N, VANDAMME, AM, HEGARTY, J, CURRY, M, NOLAN, N, KELLEHER, D, MCKIERNAN, S, HALL, WW, COMPARATIVE RATES OF NUCLEOTIDE SEQUENCE VARIATION IN THE HYPERVARIABLE REGION OF E1/E2 AND THE NS5B REGION OF HEPATITIS C VIRUS IN PATIENTS WITH A SPECTRUM OF LIVER DISEASE RESULTING FROM A COMMON SOURCE OF INFECTION, VIROLOGY, 301, 2002, p354 - 364
M. Duffy, M. Salemi, N. Sheehy, A. M. Vandamme, J. Hegarty, M. Curry, N. Nolan, D. Kelleher, S. McKiernan and W. W. Hall, Comparative rates of nucleotide sequence variation in the hypervariable region of E1/E2 and the NS5b region of hepatitis C virus in patients with a spectrum of liver disease resulting from a common source of infection, Virology, 301, (2), 2002, p354-64
M. Chen, E. A. O'Toole, J. Sanghavi, N. Mahmud, D. Kelleher, D. Weir, J. A. Fairley and D. T. Woodley, The epidermolysis bullosa acquisita antigen (type VII collagen) is present in human colon and patients with crohn's disease have autoantibodies to type VII collagen, The Journal of investigative dermatology, 118, (6), 2002, p1059-1064
FARRELL, RJ, MAHMUD, N, NOONAN, N, KELLEHER, D, KEELING, PWN, DIAGNOSTIC AND THERAPEUTIC ERCP: A LARGE SINGLE CENTRE'S EXPERIENCE, IRISH JOURNAL OF MEDICAL SCIENCE, 170, 2001, p176 - 180
R. J. Farrell, N. Noonan, N. Mahmud, M. M. Morrin, D. Kelleher and P. W. Keeling, Potential impact of magnetic resonance cholangiopancreatography on endoscopic retrograde cholangiopancreatography workload and complication rate in patients referred because of abdominal pain, Endoscopy, 33, (8), 2001, p668-75
M. G. Goggins, J. Goh, M. A. O'Connell, D. G. Weir, D. Kelleher and N. Mahmud, Soluble adhesion molecules in inflammatory bowel disease, Irish journal of medical science, 170, (2), 2001, p107-11
R. J. Farrell, N. Mahmud, N. Noonan, D. Kelleher and P. W. Keeling, Diagnostic and therapeutic ERCP: a large single centre's experience, Irish journal of medical science, 170, (3), 2001, p176-80
B. M. Ryan, A. M. Molloy, R. McManus, Q. Arfin, D. Kelleher, J. M. Scott and D. G. Weir, The methylenetetrahydrofolate reductase (MTHFR) gene in colorectal cancer: role in tumor development and significance of allelic loss in tumor progression, International journal of gastrointestinal cancer, 30, (3), 2001, p105-11
B. M. Ryan, R. McManus, J. S. Daly, E. Carton, P. W. Keeling, J. V. Reynolds and D. Kelleher, A common p73 polymorphism is associated with a reduced incidence of oesophageal carcinoma, British journal of cancer, 85, (10), 2001, p1499-503
Long A., Kelleher D., Lynch S., Volkov Y., Cutting edge: protein kinase C beta expression is critical for export of Il-2 from T cells, Journal of Immunology, 167, (2), 2001, p636-640
N. Mahmud, M. A. Kamm, J. L. Dupas, D. P. Jewell, C. A. O'Morain, D. G. Weir and D. Kelleher, Olsalazine is not superior to placebo in maintaining remission of inactive Crohn's colitis and ileocolitis: a double blind, parallel, randomised, multicentre study, Gut, 49, (4), 2001, p552-6
FARRELL, RJ, NOONAN, N, MAHMUD, N, MORRIN, MM, KELLEHER, D, KEELING, PWN, POTENTIAL IMPACT OF MAGNETIC RESONANCE CHOLANGIOPANCREATOGRAPHY ON ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY WORKLOAD AND COMPLICATION RATE IN PATIENTS REFERRED BECAUSE OF ABDOMINAL PAIN, ENDOSCOPY, 33, 2001, p668 - 675
Y. Volkov, A. Long, S. McGrath, D. Ni Eidhin and D. Kelleher, Crucial importance of PKC-beta(I) in LFA-1-mediated locomotion of activated T cells, Nature immunology, 2, (6), 2001, p508-14
VOLKOV, Y, LONG, A, MCGRATH, S, EIDHIN, DN, KELLEHER, D, CRUCIAL IMPORTANCE OF PKC-BETA(I) IN LFA-I-MEDIATED LOCOMOTION OF ACTIVATED T CELLS, NATURE IMMUNOLOGY, 2, 2001, p508 - 514
B. M. Ryan, R. McManus, J. S. Daly, E. Carton, P. W. Keeling, J. V. Reynolds and D. Kelleher, A common p73 polymorphism is associated with a reduced incidence of oesophageal carcinoma, British Journal of Cancer, 85, (10), 2001, p1499-1503
M. G. Goggins, S. A. Shah, J. Goh, A. Cherukuri, D. G. Weir, D. Kelleher and N. Mahmud, Increased urinary nitrite, a marker of nitric oxide, in active inflammatory bowel disease, Mediators of Inflammation, 10, (2), 2001, p69-73
H. M. Roche, A. M. Terres, I. B. Black, M. J. Gibney and D. Kelleher, Fatty acids and epithelial permeability: effect of conjugated linoleic acid in Caco-2 cells, Gut, 48, (6), 2001, p797-802
Ryan BM, Molloy AM, McManus R, Arfin Q, Kelleher D, Scott JM, Weir DG. , The methylenetetrahydrofolate reductase (MTHFR) gene in colorectal cancer: Role in tumor development and significance of allelic loss in tumor progression , International Journal of Gastrointestinal Cancer , 30, (3), 2001, p105 - 111
MCMAHON, C, PILKINGTON, R, SHEA, EO, KELLEHER, D, SMITH, OP, LIVER BIOPSY IN IRISH HEPATITIS C-INFECTED PATIENTS WITH INHERITED BLEEDING DISORDERS, BRITISH JOURNAL OF HAEMATOLOGY, 109, 2000, p354 - 359
R. J. Farrell, A. Murphy, A. Long, S. Donnelly, A. Cherikuri, D. O'Toole, N. Mahmud, P. W. Keeling, D. G. Weir and D. Kelleher, High multidrug resistance (P-glycoprotein 170) expression in inflammatory bowel disease patients who fail medical therapy, Gastroenterology, 118, (2), 2000, p279-88
RYAN, BM, MCMANUS, RO, DALY, JS, KEELING, PWN, WEIR, DG, LEFORT, F, KELLEHER, D, SERUM MUTANT K-RAS IN THE COLORECTAL ADENOMA-TO-CARCINOMA SEQUENCE - IMPLICATIONS FOR DIAGNOSIS, POSTOPERATIVE FOLLOW-UP, AND EARLY DETECTION OF RECURRENT DISEASE, ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 906, 2000, p29 - 30
N. K. Ghaisas, J. B. Foley, D. S. O'Briain, P. Crean, D. Kelleher and M. Walsh, Adhesion molecules in nonrheumatic aortic valve disease: endothelial expression, serum levels and effects of valve replacement, Journal of the American College of Cardiology, 36, (7), 2000, p2257-62
S. Clarke, P. Harrington, C. Condon, D. Kelleher, O. P. Smith and F. Mulcahy, Late onset hepatitis and prolonged deterioration in hepatic function associated with nevirapine therapy, International journal of STD & AIDS, 11, (5), 2000, p336-7
RYAN, BM, KELLEHER, D, REFRACTORY CELIAC DISEASE, GASTROENTEROLOGY, 119, 2000, p243 - +
Madrigal-Estebas, L., McManus, R., Byrne, B., Lynch, S., Doherty, D.G., Kelleher, D., O'Donoghue, D.P., (...), O'Farrelly, C. , Erratum: Human small intestinal epithelial cells secrete interleukin-7 and differentially express two different interleukin-7 mRNA transcripts: Implications for extrathymic T-cell differentiation (Human Immunology (1997) 58 (83)) , 2000, - 719
B. M. Ryan and D. Kelleher, Refractory celiac disease, Gastroenterology, 119, (1), 2000, p243-51
A. Murphy, A. Long, Y. Volkov and D. Kelleher, Cross-linking of LFA-1 induces secretion of macrophage inflammatory protein (MIP)-lalpha and MIP-1beta with consequent directed migration of activated lymphocytes, European journal of immunology, 30, (10), 2000, p3006-11
GHAISAS, NK, FOLEY, JB, OBRIAIN, DS, CREAN, P, KELLEHER, D, WALSH, M, ADHESION MOLECULES IN NONRHEUMATIC AORTIC VALVE DISEASE: ENDOTHELIAL EXPRESSION, SERUM LEVELS AND EFFECTS OF VALVE REPLACEMENT, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 36, 2000, p2257 - 2262
MURPHY, A, LONG, A, VOLKOV, Y, KELLEHER, D, CROSS-LINKING OF LFA-1 INDUCES SECRETION OF MACROPHAGE INFLAMMATORY PROTEIN (MIP)-1 ALPHA AND MIP-1 BETA WITH CONSEQUENT DIRECTED MIGRATION OF ACTIVATED LYMPHOCYTES, EUROPEAN JOURNAL OF IMMUNOLOGY, 30, 2000, p3006 - 3011
CLARKE, S, HARRINGTON, P, CONDON, C, KELLEHER, D, SMITH, OP, MULCAHY, F, LATE ONSET HEPATITIS AND PROLONGED DETERIORATION IN HEPATIC FUNCTION ASSOCIATED WITH NEVIRAPINE THERAPY, INTERNATIONAL JOURNAL OF STD & AIDS, 11, 2000, p336 - 337
WHITE, B, SCHMIDT, M, MURPHY, C, LIVINGSTONE, W, OTOOLE, D, LAWLER, M, ONEILL, L, KELLEHER, D, SCHWARZ, HP, SMITH, OP, ACTIVATED PROTEIN C INHIBITS LIPOPOLYSACCHARIDE-INDUCED NUCLEAR TRANSLOCATION OF NUCLEAR FACTOR KAPPA B (NF-KAPPA B) AND TUMOUR NECROSIS FACTOR ALPHA (TNF-ALPHA) PRODUCTION IN THE THP-1 MONOCYTIC CELL LINE, BRITISH JOURNAL OF HAEMATOLOGY, 110, 2000, p130 - 134
R. J. Farrell, Y. Ang, P. Kileen, D. S. O'Briain, D. Kelleher, P. W. Keeling and D. G. Weir, Increased incidence of non-Hodgkin's lymphoma in inflammatory bowel disease patients on immunosuppressive therapy but overall risk is low, Gut, 47, (4), 2000, p514-9
S. M. McKiernan, R. Hagan, M. Curry, G. S. McDonald, N. Nolan, J. Crowley, J. Hegarty, E. Lawlor and D. Kelleher, The MHC is a major determinant of viral status, but not fibrotic stage, in individuals infected with hepatitis C, Gastroenterology, 118, (6), 2000, p1124-30
C. McMahon, R. Pilkington, E. O. Shea, D. Kelleher and O. P. Smith, Liver biopsy in Irish hepatitis C-infected patients with inherited bleeding disorders, British journal of haematology, 109, (2), 2000, p354-9
B. White, M. Schmidt, C. Murphy, W. Livingstone, D. O'Toole, M. Lawler, L. O'Neill, D. Kelleher, H. P. Schwarz and O. P. Smith, Activated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor kappaB (NF-kappaB) and tumour necrosis factor alpha (TNF-alpha) production in the THP-1 monocytic cell line, British Journal of Haematology, 110, (1), 2000, p130-134
H. J. Windle, A. Fox, D. Ni Eidhin and D. Kelleher, The thioredoxin system of Helicobacter pylori, The Journal of biological chemistry, 275, (7), 2000, p5081-9
B. White, M. Schmidt, C. Murphy, W. Livingstone, D. O'Toole, M. Lawler, L. O'Neill, D. Kelleher, H. P. Schwarz and O. P. Smith, Activated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor kappaB (NF-kappaB) and tumour necrosis factor alpha (TNF-alpha) production in the THP-1 monocytic cell line, British journal of haematology, 110, (1), 2000, p130-4
M. A. O'Sullivan, N. Mahmud, D. P. Kelleher, E. Lovett and C. A. O'Morain, Patient knowledge and educational needs in irritable bowel syndrome, European journal of gastroenterology & hepatology, 12, (1), 2000, p39-43
FARRELL, RJ, MURPHY, A, LONG, A, DONNELLY, S, CHERIKURI, A, OTOOLE, D, MAHMUD, N, KEELING, PWN, WEIR, DG, KELLEHER, D, HIGH MULTIDRUG RESISTANCE (P-GLYCOPROTEIN 170) EXPRESSION IN INFLAMMATORY BOWEL DISEASE PATIENTS WHO FAIL MEDICAL THERAPY, GASTROENTEROLOGY, 118, 2000, p279 - 288
S. McKiernan and D. Kelleher, Immunogenetics of hepatitis C virus, Journal of viral hepatitis, 7 Suppl 1, 2000, p13-Apr
B. M. Ryan, R. O. McManus, J. S. Daly, P. W. Keeling, D. G. Weir, F. Lefort and D. Kelleher, Serum mutant K-ras in the colorectal adenoma-to-carcinoma sequence. Implications for diagnosis, postoperative follow-up, and early detection of recurrent disease, Annals of the New York Academy of Sciences, 906, 2000, p29-30
GHAISAS, NK, EVIDENCE OF ONGOING INFLAMMATION IN CHRONIC RHEUMATIC MITRAL VALVE DISEASE, unknown, 2000, 35, ISI Web of Science, 2000, pp527A - 527A
FARRELL, RJ, SMIDDY, PF, PILKINGTON, RM, TOBIN, AA, MOONEY, EE, TEMPERLEY, IJ, MCDONALD, GS, BOWMER, HA, WILSON, GF, KELLEHER, D, GUIDED VERSUS BLIND LIVER BIOPSY FOR CHRONIC HEPATITIS C: CLINICAL BENEFITS AND COSTS, JOURNAL OF HEPATOLOGY, 30, 1999, p580 - 587
S. McKiernan, R. Pilkington, B. Ramsay, A. Walsh, E. Sweeney and D. Kelleher, Primary cutaneous B-cell lymphoma: an association of chronic hepatitis C infection, European journal of gastroenterology & hepatology, 11, (6), 1999, p669-72
ABUZAKOUK, M, FEIGHERY, C, KELLEHER, D, OBRIAIN, DS, JONES, E, WEIR, D, CASEY, E, OFARRELLY, C, INCREASED HLA-DR AND CD44 ANTIGEN EXPRESSION IN THE GUT: EVIDENCE OF EXTRAARTICULAR IMMUNOLOGICAL ACTIVITY IN RHEUMATOID ARTHRITIS, JOURNAL OF RHEUMATOLOGY, 26, 1999, p1869 - 1876
R. J. Farrell, P. F. Smiddy, R. M. Pilkington, A. A. Tobin, E. E. Mooney, I. J. Temperley, G. S. McDonald, H. A. Bowmer, G. F. Wilson and D. Kelleher, Guided versus blind liver biopsy for chronic hepatitis C: clinical benefits and costs, Journal of hepatology, 30, (4), 1999, p580-7
Abuzakouk, M, Feighery, C, Kelleher, D, O'Briain, DS, Jones, E, Weir, D, Casey, E, O'Farrelly, C, Increased HLA-DR and CD44 antigen expression in the gut: evidence of extraarticular immunological activity in rheumatoid arthritis., The Journal of Rheumatology, 26, (9), 1999, p1869-76
N. Mahmud, D. G. Weir and D. Kelleher, Systemic levels of free 5-aminosalicylic acid depend on the nature of the 5-aminosalicyclic acid derivative and not on disease activity or extent in patients with inflammatory bowel disease, Irish journal of medical science, 168, (4), 1999, p228-32
MCKIERNAN, S, PILKINGTON, R, RAMSAY, B, WALSH, A, SWEENEY, E, KELLEHER, D, PRIMARY CUTANEOUS B-CELL LYMPHOMA: AN ASSOCIATION OF CHRONIC HEPATITIS C INFECTION, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 11, 1999, p669 - 672
M. Abuzakouk, C. Feighery, D. Kelleher, D. S. O'Briain, E. Jones, D. Weir, E. Casey and C. O'Farrelly, Increased HLA-DR and CD44 antigen expression in the gut: evidence of extraarticular immunological activity in rheumatoid arthritis, The Journal of rheumatology, 26, (9), 1999, p1869-76
KEENAN, C, PROTEIN KINASE C AND THE CYTOSKELETON, by KELLEHER, D , CELLULAR SIGNALLING, 10, 1998, p225 - 232
A. M. Terres, J. M. Pajares, D. O'Toole, S. Ahern and D. Kelleher, H pylori infection is associated with downregulation of E-cadherin, a molecule involved in epithelial cell adhesion and proliferation control, Journal of Clinical Pathology, 51, (5), 1998, p410-412
C. Keenan and D. Kelleher, Protein kinase C and the cytoskeleton, Cellular signalling, 10, (4), 1998, p225-32
Volkov Y., Long A., Kelleher D., Inside the crawling T cell: leukocyte function-associated antigen-1 cross-linking is associated with microtubule-directed translocation of protein kinase C isoenzymes beta(I) and delta, Journal of Immunology , 161, (12), 1998, p6487-95
MADRIGAL-ESTEBAS, L, MCMANUS, R, BYRNE, B, LYNCH, S, DOHERTY, DG, KELLEHER, D, ODONOGHUE, DP, FEIGHERY, C, OFARRELLY, C, HUMAN SMALL INTESTINAL EPITHELIAL CELLS SECRETE INTERLEUKIN-7 AND DIFFERENTIALLY EXPRESS TWO DIFFERENT INTERLEUKIN-7 MRNA TRANSCRIPTS: IMPLICATIONS FOR EXTRATHYMIC T-CELL DIFFERENTIATION, HUMAN IMMUNOLOGY, 58, 1998, p83 - 90
DUFFY, M, LONG TERM GENETIC VARIATION OF HEPATITIS C VIRUS IN A COHORT OF PATIENTS INFECTED FROM A SINGLE SOURCE., unknown, 1998, 28, ISI Web of Science, 1998, pp683A - 683A
A. M. Terres, J. M. Pajares, A. M. Hopkins, A. Murphy, A. Moran, A. W. Baird and D. Kelleher, Helicobacter pylori disrupts epithelial barrier function in a process inhibited by protein kinase C activators, Infection and Immunity, 66, (6), 1998, p2943-2950
B. M. Ryan, G. S. McDonald, R. Pilkington and D. Kelleher, The development of hepatic granulomas following interferon-alpha2b therapy for chronic hepatitis C infection, European journal of gastroenterology & hepatology, 10, (4), 1998, p349-51
C. Keenan, Y. Volkov, D. Kelleher and A. Long, Subcellular localization and translocation of protein kinase C isoforms zeta and epsilon in human peripheral blood lymphocytes, International Immunology, 9, (10), 1997, p1431-1439
L. Madrigal-Estebas, R. McManus, B. Byrne, S. Lynch, D. G. Doherty, D. Kelleher, D. P. O'Donoghue, C. Feighery and C. O'Farrelly, Human small intestinal epithelial cells secrete interleukin-7 and differentially express two different interleukin-7 mRNA Transcripts: implications for extrathymic T-cell differentiation, Human immunology, 58, (2), 1997, p83-90
BUCKLEY, M, CULHANE, A, DRUMM, B, KEANE, C, MORAN, AP, OCONNOR, HJ, COLLINS, J, KELLEHER, D, MCAVINCHEY, D, SLOAN, J, OMORAIN, C, GUIDELINES FOR THE MANAGEMENT OF HELICOBACTER PYLORI-RELATED UPPER GASTROINTESTINAL DISEASES, IRISH JOURNAL OF MEDICAL SCIENCE, 165, 1997, p2 - 11
H. J. Windle and D. Kelleher, Identification and characterization of a metalloprotease activity from Helicobacter pylori, Infection and Immunity, 65, (8), 1997, p3132-3137
C. N. Shahi, N. K. Ghaisas, M. Goggins, B. Foley, P. Crean, D. Kelleher and M. Walsh, Elevated levels of circulating soluble adhesion molecules in patients with nonrheumatic aortic stenosis, The American journal of cardiology, 79, (7), 1997, p980-2
KEENAN, C, KELLEHER, D, PROTEIN KINASE C AND T CELL FUNCTION, by LONG, A , BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1358, 1997, p113 - 126
M. A. O'Connell, D. Kelleher, R. M. Liskamp, N. Hall, L. A. O'Neill and A. Long, TNF-mediated cytotoxicity of L929 cells: role of staurosporine in enhancement of cytotoxicity and translocation of protein kinase C isozymes, Cytokine, 9, (2), 1997, p83-92
TERRES, AM, H-PYLORI INDUCE INCREASED PERMEABILITY IN T84 EPITHELIAL MONOLAYERS, unknown, 1997, 41, ISI Web of Science, 1997, ppA23 - A23
C. Keenan, A. Long, Y. Volkov and D. Kelleher, Protein kinase C isotypes theta, delta and eta in human lymphocytes: differential responses to signalling through the T-cell receptor and phorbol esters, Immunology, 90, (4), 1997, p557-563
SHAHI, CN, GHAISAS, NK, GOGGINS, M, FOLEY, B, CREAN, P, KELLEHER, D, WALSH, M, ELEVATED LEVELS OF CIRCULATING SOLUBLE ADHESION MOLECULES IN PATIENTS WITH NONRHEUMATIC AORTIC STENOSIS, AMERICAN JOURNAL OF CARDIOLOGY, 79, 1997, p980 - &
L. Madrigal-Estebas, R. McManus, B. Byrne, S. Lynch, D. G. Doherty, D. Kelleher, D. P. O'Donoghue, C. Feighery and C. O'Farrelly, Human small intestinal epithelial cells secrete interleukin-7 and differentially express two different interleukin-7 mRNA Transcripts: implications for extrathymic T-cell differentiation, Human Immunology, 58, (2), 1997, p83-90
C. Keenan, A. Long and D. Kelleher, Protein kinase C and T cell function, Biochimica et biophysica acta, 1358, (2), 1997, p113-26
O'Connell MA, Kelleher D, Liskamp RM, Hall N, O'Neill LA, Long A., TNF-mediated cytotoxicity of L929 cells: role of staurosporine in enhancement of cytotoxicity and translocation of protein kinase C isozymes., Cytokine, 9, (2), 1997, p83 - 92
M. A. O'Connell, D. Kelleher, R. M. Liskamp, N. Hall, L. A. O'Neill and A. Long, TNF-mediated cytotoxicity of L929 cells: role of staurosporine in enhancement of cytotoxicity and translocation of protein kinase C isozymes, Cytokine, 9, (2), 1997, p83-92
C. T. Taylor, A. Murphy, D. Kelleher and A. W. Baird, Changes in barrier function of a model intestinal epithelium by intraepithelial lymphocytes require new protein synthesis by epithelial cells, Gut, 40, (5), 1997, p634-640
R. McManus, A. G. Wilson, J. Mansfield, D. G. Weir, G. W. Duff and D. Kelleher, TNF2, a polymorphism of the tumour necrosis-alpha gene promoter, is a component of the celiac disease major histocompatibility complex haplotype, European Journal of Immunology, 26, (9), 1996, p2113-2118
X. Fan, A. Long, M. Goggins, P. W. Keeling and D. Kelleher, Expression of CD44 and its variants on gastric epithelial cells of patients with Helicobacter pylori colonisation, Gut, 38, (4), 1996, p507-512
X. G. Fan, D. Kelleher, X. J. Fan, H. X. Xia and P. W. Keeling, Helicobacter pylori increases proliferation of gastric epithelial cells, Gut, 38, (1), 1996, p19-22
WINGETT, D, LONG, A, KELLEHER, D, MAGNUSON, NS, PIM-1 PROTO-ONCOGENE EXPRESSION IN ANTI-CD3-MEDIATED T CELL ACTIVATION IS ASSOCIATED WITH PROTEIN KINASE C ACTIVATION AND IS INDEPENDENT OF RAF-1, JOURNAL OF IMMUNOLOGY, 156, 1996, p549 - 557
R. McManus, M. Moloney, M. Borton, A. Finch, Y. T. Chuan, E. Lawlor, D. G. Weir and D. Kelleher, Association of celiac disease with microsatellite polymorphisms close to the tumor necrosis factor genes, Human immunology, 45, (1), 1996, p24-31
R. J. Farrell, N. Noonan, I. M. Khan, M. Goggins, D. P. Kelleher and P. W. Keeling, Carcinoma of the ampulla of Vater: a tumour with a poor prognosis?, European journal of gastroenterology & hepatology, 8, (2), 1996, p139-44
M. Goggins, A. Whelan and D. Kelleher, The immunology of coeliac disease, Annales de medecine interne, 147, (1), 1996, p40-8
MCMANUS, R, MOLONEY, M, BORTON, M, FINCH, A, CHUAN, YT, LAWLOR, E, WEIR, DG, KELLEHER, D, ASSOCIATION OF CELIAC DISEASE WITH MICROSATELLITE POLYMORPHISMS CLOSE TO THE TUMOR NECROSIS FACTOR GENES, HUMAN IMMUNOLOGY, 45, 1996, p24 - 31
Abuzakouk, M, Kelleher, D, Feighery, C, O'Farrelly, C, Increased HLA-DR and decreased CD3 on human intestinal intraepithelial lymphocytes: evidence of activation?, Gut, 39, (3), 1996, p396-400
M. Buckley, A. Culhane, B. Drumm, C. Keane, A. P. Moran, H. J. O'Connor, J. Collins, D. Kelleher, D. McAvinchey, J. Sloan and C. O'Morain, Guidelines for the management of Helicobacter pylori-related upper gastrointestinal diseases. Irish Helicobacter Pylori Study Group, Irish journal of medical science, 165 Suppl 5, 1996, p01-Nov
LANG, CC, BROWN, RM, KINIRONS, MT, DEATHRIDGE, MA, GUENGERICH, FP, KELLEHER, D, OBRIAIN, DS, GHISHAN, FK, WOOD, AJJ, DECREASED INTESTINAL CYP3A IN CELIAC DISEASE: REVERSAL AFTER SUCCESSFUL GLUTEN-FREE DIET: A POTENTIAL SOURCE OF INTERINDIVIDUAL VARIABILITY IN FIRST-PASS DRUG METABOLISM, CLINICAL PHARMACOLOGY & THERAPEUTICS, 59, 1996, p41 - 46
N. Mahmud, G. S. McDonald, D. Kelleher and D. G. Weir, Microalbuminuria correlates with intestinal histopathological grading in patients with inflammatory bowel disease, Gut, 38, (1), 1996, p99-103
D. Wingett, A. Long, D. Kelleher and N. S. Magnuson, pim-1 proto-oncogene expression in anti-CD3-mediated T cell activation is associated with protein kinase C activation and is independent of Raf-1, Journal of immunology (Baltimore, Md, 156, (2), 1996, p549-57
R. McManus, M. Moloney, M. Borton, A. Finch, Y. T. Chuan, E. Lawlor, D. G. Weir and D. Kelleher, Association of celiac disease with microsatellite polymorphisms close to the tumor necrosis factor genes, Human Immunology, 45, (1), 1996, p24-31
R. McManus, A. G. Wilson, J. Mansfield, D. G. Weir, G. W. Duff and D. Kelleher, TNF2, a polymorphism of the tumour necrosis-alpha gene promoter, is a component of the celiac disease major histocompatibility complex haplotype, European journal of immunology, 26, (9), 1996, p2113-8
E. Corrigan, D. Kelleher, C. Feighery and A. Long, Protein kinase C isoform expression in CD45RA+ and CD45RO+ T lymphocytes, Immunology, 85, (2), 1995, p299-303
KELLEHER, D, MURPHY, A, FEIGHERY, C, CASEY, EB, LEUKOCYTE-FUNCTION-ASSOCIATED-ANTIGEN-1 (LFA-1) AND CD44 ARE SIGNALING MOLECULES FOR CYTOSKELETON-DEPENDENT MORPHOLOGICAL-CHANGES IN ACTIVATED T-CELLS, JOURNAL OF LEUKOCYTE BIOLOGY, 58, 1995, p539 - 546
KEENAN, C, KELLEHER, D, LONG, A, REGULATION OF NONCLASSICAL PROTEIN-KINASE-C ISOENZYMES IN A HUMAN T-CELL LINE, EUROPEAN JOURNAL OF IMMUNOLOGY, 25, 1995, p13 - 17
MCDEVITT, J, FEIGHERY, C, OFARRELLY, C, MARTIN, G, WEIR, DG, KELLEHER, D, EFFECTS OF TUMOR-NECROSIS-FACTOR-ALPHA ON BRDU INCORPORATION IN CULTURED HUMAN ENTEROCYTES, MEDIATORS OF INFLAMMATION, 4, 1995, p31 - 37
D. Kelleher, A. Murphy, C. Feighery and E. B. Casey, Leukocyte function-associated antigen 1 (LFA-1) and CD44 are signalling molecules for cytoskeleton-dependent morphological changes in activated T cells, Journal of Leukocyte Biology, 58, (5), 1995, p539-546
J. McDevitt, C. Feighery, C. O'Farrelly, G. Martin, D.G. Weir, D.K. Kelleher. , Effects of tumour necrosis factor on BrdU incorporation in cultured human enterocytes., The Journal of Biological Chemistry, 4, 1995, p31-37
N. Mahmud, M. A. O'Connell, J. Stinson, M. G. Goggins, D. G. Weir and D. Kelleher, Tumour necrosis factor-alpha and microalbuminuria in patients with inflammatory bowel disease, European journal of gastroenterology & hepatology, 7, (3), 1995, p215-9
Cleere R, Long A, Kelleher D, O'Neill LA., Autocrine regulation of the transcription factor NF kappa B by TNF alpha in the human T cell lymphoma line Hut 78., Biochemical Society Transactions, 23, (1), 1995, pS113 - S113
LYNCH, S, KELLEHER, D, MCMANUS, R, OFARRELLY, C, RAG1 AND RAG2 EXPRESSION IN HUMAN INTESTINAL EPITHELIUM - EVIDENCE OF EXTRATHYMIC T-CELL DIFFERENTIATION, EUROPEAN JOURNAL OF IMMUNOLOGY, 25, 1995, p1143 - 1147
S. Lynch, D. Kelleher, R. McManus and C. O'Farrelly, RAG1 and RAG2 expression in human intestinal epithelium: evidence of extrathymic T cell differentiation, European journal of immunology, 25, (5), 1995, p1143-7
X. G. Fan, X. J. Fan, H. X. Xia, P. W. Keeling and D. Kelleher, Up-regulation of CD44 and ICAM-1 expression on gastric epithelial cells by H. pylori, APMIS, 103, (10), 1995, p744-8
Lynch, S, Kelleher, D, McManus, R, O'Farrelly, C, RAG1 and RAG2 expression in human intestinal epithelium: evidence of extrathymic T cell differentiation., European journal of immunology, 25, (5), 1995, p1143-7
S. Lynch, D. Kelleher, R. McManus and C. O'Farrelly, RAG1 and RAG2 expression in human intestinal epithelium: evidence of extrathymic T cell differentiation, European journal of immunology, 25, (5), 1995, p1143-1147
KELLEHER, D, MURPHY, A, HALL, N, OMARY, MB, KEARNS, G, LONG, A, CASEY, EB, EXPRESSION OF CD44 ON RHEUMATOID SYNOVIAL-FLUID LYMPHOCYTES, ANNALS OF THE RHEUMATIC DISEASES, 54, 1995, p566 - 570
OCONNELL, MA, CLEERE, R, LONG, A, ONEILL, LAJ, KELLEHER, D, CELLULAR PROLIFERATION AND ACTIVATION OF NF-KAPPA-B ARE INDUCED BY AUTOCRINE PRODUCTION OF TUMOR-NECROSIS-FACTOR-ALPHA IN THE HUMAN T-LYMPHOMA LINE HUT-78, JOURNAL OF BIOLOGICAL CHEMISTRY, 270, 1995, p7399 - 7404
D. Kelleher, A. Murphy, N. Hall, M. B. Omary, G. Kearns, A. Long and E. B. Casey, Expression of CD44 on rheumatoid synovial fluid lymphocytes, Annals of the Rheumatic Diseases, 54, (7), 1995, p566-570
FAN, XJ, LONG, A, FAN, XG, KEELING, PWN, KELLEHER, D, ADHESION MOLECULE EXPRESSION ON GASTRIC INTRAEPITHELIAL LYMPHOCYTES OF PATIENTS WITH HELICOBACTER-PYLORI INFECTION, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 7, 1995, p541 - 546
R. Cleere, A. Long, D. Kelleher and L. A. O'Neill, Autocrine regulation of the transcription factor NF kappa B by TNF alpha in the human T cell lymphoma line Hut 78, Biochemical Society transactions, 23, (1), 1995, p113S
Maria A. O'Connell, Roisin Cleere , Aideen Long , Luke A. J. O'Neill , Dermot Kelleher , Cellular Proliferation and Activation of NFB Are Induced by Autocrine Production of Tumor Necrosis Factor in the Human T Lymphoma Line HuT 78 , Journal of Biological Chemistry, 270, (13), 1995, p7399 - 7404
CORRIGAN, E, KELLEHER, D, FEIGHERY, C, LONG, A, PROTEIN-KINASE-C ISOFORM EXPRESSION IN CD45RA(+) AND CD45RO(+) T-LYMPHOCYTES, IMMUNOLOGY, 85, 1995, p299 - 303
CLEERE, R, LONG, A, KELLEHER, D, ONEILL, LAJ, AUTOCRINE REGULATION OF THE TRANSCRIPTION FACTOR NF-KAPPA-B BY TNF-ALPHA IN THE HUMAN T-CELL LYMPHOMA LINE HUT 78, BIOCHEMICAL SOCIETY TRANSACTIONS, 23, 1995, pS113 - S113
D. Kelleher, A. Murphy, O. Sheils, A. Long and J. McDevitt, Tyrosine phosphorylation in the human duodenum, Gut, 36, (1), 1995, p34-8
X. Fan, A. Long, P. W. Keeling and D. Kelleher, Adhesion molecule expression on gastric intra-epithelial lymphocytes of patients with Helicobacter pylori infection, European journal of gastroenterology & hepatology, 7, (6), 1995, p541-6
C. Keenan, D. Kelleher and A. Long, Regulation of non-classical protein kinase C isoenzymes in a human T cell line, European journal of immunology, 25, (1), 1995, p13-Jul
M. A. O'Connell, R. Cleere, A. Long, L. A. O'Neill and D. Kelleher, Cellular proliferation and activation of NF kappa B are induced by autocrine production of tumor necrosis factor alpha in the human T lymphoma line HuT 78, The Journal of Biological Chemistry, 270, (13), 1995, p7399-7404
Kelleher D, Murphy A, Sheils O, Long A, McDevitt J., Tyrosine phosphorylation in the human duodenum., Gut. , 36, (1), 1995, p34-38
Lawler M, Humphries P, O'Farrelly C, Hoey H, Sheils O, Jeffers M, O'Briain DS, Kelleher D., Adenovirus 12 E1A gene detection by polymerase chain reaction in both the normal and coeliac duodenum., Gut. , 35, (9), 1994, p1226-1232
LAWLER, M, HUMPHRIES, P, OFARRELLY, C, HOEY, H, SHEILS, O, JEFFERS, M, OBRIAIN, DS, KELLEHER, D, ADENOVIRUS-12 E1A GENE DETECTION BY POLYMERASE CHAIN-REACTION IN BOTH THE NORMAL AND CELIAC DUODENUM, GUT, 35, 1994, p1226 - 1232
K. J. O'Byrne, M. G. Goggins, G. S. McDonald, P. A. Daly, D. P. Kelleher and D. G. Weir, A metastatic neuroendocrine anaplastic small cell tumor in a patient with multiple endocrine neoplasia type 1 syndrome. Assessment of disease status and response to doxorubicin, cyclophosphamide, etoposide chemotherapy through scintigraphic imaging with 111In-pentetreotide, Cancer, 74, (8), 1994, p2374-8
J. McDevitt, C. O'Farrelly, D.G. Weir, M. Bishr Omary, C. Feighery, D. Kelleher, Proliferation-associated marker in the coeliac duodenum, Eur J Gastroenterol Hepatol, 6, (3), 1994, p223-228
N. Mahmud, J. Stinson, M. A. O'Connell, T. J. Mantle, P. W. Keeling, J. Feely, D. G. Weir and D. Kelleher, Microalbuminuria in inflammatory bowel disease, Gut, 35, (11), 1994, p1599-1604
X. J. Fan, A. Chua, C. N. Shahi, J. McDevitt, P. W. Keeling and D. Kelleher, Gastric T lymphocyte responses to Helicobacter pylori in patients with H pylori colonisation, Gut, 35, (10), 1994, p1379-1384
D. Kelleher, A. Murphy, S. Lynch and C. O'Farrelly, Adhesion molecules utilized in binding of intraepithelial lymphocytes to human enterocytes, European journal of immunology, 24, (4), 1994, p1013-6
M. Goggins and D. Kelleher, Celiac disease and other nutrient related injuries to the gastrointestinal tract, The American journal of gastroenterology, 89, (8 Suppl), 1994, pS2-17
KELLEHER, D, MURPHY, A, LYNCH, S, OFARRELLY, C, ADHESION MOLECULES UTILIZED IN BINDING OF INTRAEPITHELIAL LYMPHOCYTES TO HUMAN ENTEROCYTES, EUROPEAN JOURNAL OF IMMUNOLOGY, 24, 1994, 1013 - 1016
GOGGINS, M, KELLEHER, D, CELIAC-DISEASE AND OTHER NUTRIENT RELATED INJURIES TO THE GASTROINTESTINAL-TRACT, AMERICAN JOURNAL OF GASTROENTEROLOGY, 89, 1994, pS2 - S17
MAHMUD, N, STINSON, J, OCONNELL, MA, MANTLE, TJ, KEELING, PWN, FEELY, J, WEIR, DG, KELLEHER, D, MICROALBUMINURIA IN INFLAMMATORY BOWEL-DISEASE, GUT, 35, 1994, p1599 - 1604
MCDEVITT, J, OFARRELLY, C, WEIR, DG, OMARY, MB, FEIGHERY, C, KELLEHER, D, PROLIFERATION-ASSOCIATED MARKERS IN THE CELIAC DUODENUM, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 6, 1994, p223 - 228
FAN, XJ, CHUA, A, SHAHI, CN, MCDEVITT, J, KEELING, PWN, KELLEHER, D, GASTRIC T-LYMPHOCYTE RESPONSES TO HELICOBACTER-PYLORI IN PATIENTS WITH HELICOBACTER-PYLORI COLONIZATION, GUT, 35, 1994, p1379 - 1384
MADRIGAL, L, LYNCH, S, FEIGHERY, C, WEIR, D, KELLEHER, D, OFARRELLY, C, FLOW CYTOMETRIC ANALYSIS OF SURFACE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II EXPRESSION ON HUMAN EPITHELIAL-CELLS PREPARED FROM SMALL INTESTINAL BIOPSIES, JOURNAL OF IMMUNOLOGICAL METHODS, 158, 1993, p207 - 214
A. Murphy, K. C. Breen, A. Long, C. Feighery, E. B. Casey and D. Kelleher, Neurofilament expression in human T lymphocytes, Immunology, 79, (1), 1993, p167-170
FAN, XJ, CHUA, A, OCONNELL, MA, KELLEHER, D, KEELING, PWN, INTERFERON-GAMMA AND TUMOR-NECROSIS-FACTOR PRODUCTION IN PATIENTS WITH HELICOBACTER-PYLORI INFECTION, IRISH JOURNAL OF MEDICAL SCIENCE, 162, 1993, p408 - 411
L. Madrigal, S. Lynch, C. Feighery, D. Weir, D. Kelleher and C. O'Farrelly, Flow cytometric analysis of surface major histocompatibility complex class II expression on human epithelial cells prepared from small intestinal biopsies, Journal of immunological methods, 158, (2), 1993, p207-14
LYNCH, S, KELLEHER, D, FEIGHERY, C, WEIR, DG, OFARRELLY, C, FLOW CYTOMETRIC ANALYSIS OF INTRAEPITHELIAL LYMPHOCYTES FROM HUMAN SMALL-INTESTINAL BIOPSIES REVEALS POPULATIONS OF CD4+CD8+ AND CD8-ALPHA-ALPHA+ CELLS, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 5, 1993, p907 - 912
LONG, A, KELLEHER, D, CONVENTIONAL PROTEIN-KINASE-C ISOFORMS ARE NOT ESSENTIAL FOR CELLULAR PROLIFERATION OF A T-CELL LYMPHOMA LINE, FEBS LETTERS, 333, 1993, p243 - 247
MURPHY, A, BREEN, KC, LONG, A, FEIGHERY, C, CASEY, EB, KELLEHER, D, NEUROFILAMENT EXPRESSION IN HUMAN T-LYMPHOCYTES, IMMUNOLOGY, 79, 1993, 167 - 170
A. Long and D. Kelleher, Conventional protein kinase C isoforms are not essential for cellular proliferation of a T cell lymphoma line, FEBS letters, 333, (3), 1993, p243-7
LONG, A, OCONNELL, M, LISKAMP, RMJ, KELLEHER, D, REGULATION OF CD3 EXPRESSION IN A PROTEIN-KINASE-C ISOZYME-DEFICIENT T-CELL LINE, IMMUNOLOGY, 80, 1993, 654 - 657
X. J. Fan, A. Chua, M. A. O'Connell, D. Kelleher and P. W. Keeling, Interferon-gamma and tumour necrosis factor production in patients with Helicobacter pylori infection, Irish journal of medical science, 162, (10), 1993, p408-11
A. Long, M. O'Connell, R. M. Liskamp and D. Kelleher, Regulation of CD3 expression in a protein kinase C isozyme-deficient T-cell line, Immunology, 80, (4), 1993, p654-7
D. Kelleher and A. Long, Development and characterization of a protein kinase C beta-isozyme-deficient T-cell line, FEBS letters, 301, (3), 1992, p310-4
MAXWELL, WJ, KELLEHER, D, KEATING, JJ, HOGAN, FP, BLOOMFIELD, FJ, MACDONALD, GS, KEELING, PWN, ENHANCED SECRETION OF PROSTAGLANDIN-E2 BY TISSUE-FIXED MACROPHAGES IN COLONIC-CARCINOMA, DIGESTION, 47, 1991, p160 - 166
KELLEHER, D, FEIGHERY, C, WEIR, DG, CHEMILUMINESCENCE BY POLYMORPHONUCLEAR LEUKOCYTE SUBPOPULATIONS IN CHRONIC INFLAMMATORY BOWEL-DISEASE - INFLUENCE OF THE CELL-SEPARATION PROCEDURE, DIGESTION, 45, 1990, p158 - 165
D. Kelleher, A. Murphy and D. Cullen, Leukocyte function-associated antigen 1 (LFA-1) is a signaling molecule for cytoskeletal changes in a human T cell line, European journal of immunology, 20, (10), 1990, p2351-4
KELLEHER, D, MURPHY, A, CULLEN, D, LEUKOCYTE FUNCTION-ASSOCIATED ANTIGEN-1 (LFA-1) IS A SIGNALING MOLECULE FOR CYTOSKELETAL CHANGES IN A HUMAN T-CELL LINE, EUROPEAN JOURNAL OF IMMUNOLOGY, 20, 1990, 2351 - 2354
D. Kelleher, C. Feighery and D. G. Weir, Chemiluminescence by polymorphonuclear leucocyte subpopulations in chronic inflammatory bowel disease. Influence of the cell separation procedure, Digestion, 45, (3), 1990, p158-65
W. J. Maxwell, D. Kelleher, J. J. Keating, F. P. Hogan, F. J. Bloomfield, G. S. MacDonald and P. W. Keeling, Enhanced secretion of prostaglandin E2 by tissue-fixed macrophages in colonic carcinoma, Digestion, 47, (3), 1990, p160-6
Kelleher, D., Defective suppression in the autologous mixed lymphocyte reaction in patients with Crohn's disease, Gut, 30, (6), 1989, p839 - 844
ORIORDAN, JW, KELLEHER, D, WILLIAMS, Y, BLOOMFIELD, FJ, EFFECT OF LITHIUM-THERAPY ON INFLAMMATORY RESPONSE, INFLAMMATION, 10, 1986, p49 - 57
KELLEHER, D, JACKSON, J, WEIR, DG, FEIGHERY, C, PRIMARY BILIARY-CIRRHOSIS - AN UNDERESTIMATED DISORDER, IRISH JOURNAL OF MEDICAL SCIENCE, 155, 1986, p190 - 193
D. Kelleher, F. J. Bloomfield, T. Lenehan, M. Griffin, C. Feighery, and S. R. McCann, Chronic granulomatous disease presenting as an oculomucocutaneous syndrome mimicking Behçet's syndrome, Postgraduate Medical Journal, 62, (728), 1986, p489 - 491
KELLEHER, D, NEUTROPHIL LUMINESCENCE IN CHRONIC INFLAMMATORY BOWEL-DISEASE (CIBD), unknown, 1982, 23, ISI Web of Science, 1982, ppA895 - A896
Non-Peer-Reviewed Publications
Thomas Frodl, Yolande Ferguson, Andrew Fagan, Danusia Lisiecka, Angela Carballedo, Ian Daly, James Meaney & Dermot Kelleher, Microstructural Correlates of Resilience against Major Depressive Disorder: Epigenetic Mechanisms?, 2010
Research Expertise
Recognition
Awards and Honours
WG Smith Prize in Pharmacology
MB, BCh, BAO, BA (Hons)
Arthur Ball Prize for Second Place in Surgery at Final MB Examination
First Class Honours in Medicine at Final MB Examination
Trinity College Travelling Scholarship in Medicine
Wellcome Trust Senior Fellow in Clinical Science
St Luke's Medal, Royal Academy of Medicine in Ireland
Graves Medal, Royal Academy of Medicine