Caitríona Lally

Affiliation(s):
Trinity College Dublin

Department:
Dept. of Mechanical, Manufacturing & Biomedical Engineering, School of Engineering

Research interests:
Urological Tissue Biomechanics, Urological medical devices - male and female artificial urinary sphincters and mid urethral slings, computational and benchtop models of the male and female reproductive ssymtes,

PubMed Profile:
https://scholar.google.com/citations?user=nV42m5cAAAAJ&hl=en>

ORCID Profile
https://orcid.org/0000-0003-4141-1685

Biography

I am Professor in Biomedical Engineering in the Department of Mechanical, Manufacturing and Biomedical Engineering at Trinity College Dublin, Associate Dean of Innovation, and a Principal Investigator in the Trinity Centre for Biomedical Engineering and AMBER.

I am a biomedical engineer with extensive experience in biomechanics, biomaterials, medical-device development and translational research. My work combines experimental testing, computational modelling, advanced tissue characterisation and clinical collaboration to understand disease and develop improved diagnostic and therapeutic technologies. I have held senior academic leadership roles and have considerable experience in interdisciplinary research, research strategy, industry engagement, innovation and commercialisation.

My research includes the biomechanical characterisation of soft tissues and disease processes, alongside the design and evaluation of implantable and catheter-based medical devices. I collaborate extensively with clinicians, researchers and industry partners to progress technologies from early-stage concepts through validation, commercialisation and potential clinical application.
These capabilities are directly relevant to reproductive sciences and women’s health, including understanding the behaviour of reproductive and pelvic tissues; developing improved diagnostic, monitoring and therapeutic devices; evaluating biomaterials and implants; and creating patient-specific models to inform clinical decisions and device design.

Through the Centre, I would seek to connect clinical priorities in women’s health with Trinity’s strengths in biomedical engineering, innovation and medical-device development. I can contribute to interdisciplinary projects, external funding applications, industry partnerships and the translation of research into meaningful benefits for women across the life course.

Publications

1. Bose, S., Fereidoonnezhad, B., Akbarzadeh Khorshidi, M., Watschke, B., Mareena, E., Nolan, D., Cooney, S., Cullen, I.M. and Lally, C. (2023). “The role of tissue biomechanics in the implantation and performance of inflatable penile prostheses: current state of the art and future perspective.” Sexual Medicine Reviews, 11, 268–277. https://doi.org/10.1093/sxmrev/qead013 

2. Bose, S., Akbarzadeh Khorshidi, M., Johnston, R.D., Watschke, B., Mareena, E. and Lally, C. (2024). “Experimental testing combined with inverse-FE for mechanical characterisation of penile tissues.” Acta Biomaterialia, 179, 180–191. https://doi.org/10.1016/j.actbio.2024.03.013 

3. Akbarzadeh Khorshidi, M., Bose, S., Watschke, B., Mareena, E. and Lally, C. (2024). “Characterisation of human penile tissue properties using experimental testing combined with multi-target inverse finite element modelling.” Acta Biomaterialia, 184, 226–238. https://doi.org/10.1016/j.actbio.2024.06.035 

4. Akbarzadeh Khorshidi, M., Bose, S., Watschke, B., Mareena, E., Sinnott, T. and Lally, C. (2025). “Urological benchtop and in silico models validated by human penile tissue inflation tests.” Annals of Biomedical Engineering, 53(12), 3314–3328. https://doi.org/10.1007/s10439-025-03852-6 

5. Akbarzadeh Khorshidi, M., Bose, S., Cullen, I.M., Sullivan, J., Johnston, R., Patterson, K., Watschke, B., Sinnott, T., Mareena, E. and Lally, C. (2026). “Ex vivo testing of inflatable penile prosthesis in human cadaveric penis with paired in silico model offering surgical and biomechanical insights.” The Journal of Sexual Medicine, 23(5), qdag109. https://doi.org/10.1093/jsxmed/qdag109