How to create a difference in DNA without changing DNA sequence? Advice from bacteria
In Dr Carsten Kröger’s Lab, we study Acinetobacter baumannii, which can cause blood, urinary tract, lung (pneumonia), and wound infections.
These bacteria are constantly evolving to avoid the effects of antibiotics developed to kill them. Many strains are multidrug-resistant, which means that they can resist many antibiotics.
These bacteria are #1 in the WHO list of bacteria that require urgent development of new drugs.
Bacteria use DNA methylation to regulate many cellular processes and promote diversity in genetically similar populations.
Anna's research aims to understand the role of methylation in Acinetobacter baumannii life to find new ways to treat the infections caused by bacteria. This talk will cover bacterial antibiotic resistance and the role of methylation in bacterial regulation and show how scientists study the functions of bacterial genes in the lab.
Any questions are welcome!
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Dr Anna Ershova's project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 896441.