Skip to main content

Trinity College Dublin, The University of Dublin

Trinity Menu Trinity Search



Professor John Reynolds
Professor & Head of Department, Surgery

Publications and Further Research Outputs

Peer-Reviewed Publications

Griffiths, E.A. and Halle-Smith, J.M. and Kamarajah, S.K. and Evans, R.P.T. and Nepogodiev, D. and Hodson, J. and Bundred, J.R. and Gockel, I. and Gossage, J.A. and Isik, A. and Kauppila, J.H. and Kidane, B. and Mahendran, H.A. and Negoi, I. and Okonta, K.E. and Sayyed, R. and van Hillegersberg, R. and Vohra, R.S. and Wijnhoven, B.P.L. and Singh, P. and Griffiths, E.A. and Alderson, D. and Bundred, J. and Gossage, J. and Jefferies, B. and McKay, S. and Mohamed, I. and Siaw- Acheampong, K. and Vohra, R. and Wanigasooriya, K. and Whitehouse, T. and Gjata, A. and Moreno, J.I. and Takeda, F.R. and Guevara Castro, R. and Bekele, A. and Harustiak, T. and Kechagias, A. and Bagajevas, A. and Kennedy, A. and Da Roit, A. and Azagra, J.S. and Mejía-Fernández, L. and El Kafsi, J. and Sayyed, R.H. and Sousa, M. and Sampaio, A.S. and Blanco, R. and Wallner, B. and Schneider, P.M. and Hsu, P.K. and Gananadha, S. and Wills, V. and Devadas, M. and Duong, C. and Talbot, M. and Hii, M.W. and Jacobs, R. and Andreollo, N.A. and Johnston, B. and Darling, G. and Isaza-Restrepo, A. and Rosero, G. and Arias- Amézquita, F. and Raptis, D. and Gaedcke, J. and Reim, D. and Izbicki, J. and Egberts, J.H. and Dikinis, S. and Kjaer, D.W. and Larsen, M.H. and Achiam, M.P. and Saarnio, J. and Theodorou, D. and Liakakos, T. and Korkolis, D.P. and Robb, W.B. and Collins, C. and Murphy, T. and Reynolds, J. and Tonini, V. and Migliore, M. and Bonavina, L. and Valmasoni, M. and Bardini, R. and Weindelmayer, J. and Terashima, M. and White, R.E. and Alghunaim, E. and Elhadi, M. and Leon-Takahashi, A.M. and Medina-Franco, H. and Lau, P.C. and Heisterkamp, J. and Rosman, C. and Beban, G. and Babor, R. and Gordon, A. and Rossaak, J.I. and Pal, K.M.I. and Qureshi, A.U. and Naqi, S.A. and Syed, A.A. and Barbosa, J. and Vicente, C.S. and Leite, J. and Freire, J. and Casaca, R. and Costa, R.C.T. and Scurtu, R.R. and Mogoanta, S.S. and Bolca, C. and Constantinoiu, S. and Sekhniaidze, D. and BjeloviÄ , M. and So, J.B.Y. and GaÄ evski, G. and Loureiro, C. and Pera, M. and Bianchi, A. and Moreno Gijón, M. and Martín Fernández, J. and Trugeda Carrera, M.S. and Vallve-Bernal, M. and Cítores Pascual, M.A. and Elmahi, S. and Halldestam, I. and Hedberg, J. and Mönig, S. and Gutknecht, S. and Tez, M. and Guner, A. and Tirnaksiz, M.B. and Colak, E. and Sevinç, B. and Hindmarsh, A. and Khan, I. and Khoo, D. and Byrom, R. and Gokhale, J. and Wilkerson, P. and Jain, P. and Chan, D. and Robertson, K. and Iftikhar, S. and Skipworth, R. and Forshaw, M. and Higgs, S. and Nijjar, R. and Viswanath, Y.K.S. and Turner, P. and Dexter, S. and Boddy, A. and Allum, W.H. and Oglesby, S. and Cheong, E. and Beardsmore, D. and Maynard, N. and Berrisford, R. and Mercer, S. and Puig, S. and Melhado, R. and Kelty, C. and Underwood, T. and Dawas, K. and Lewis, W. and Al-Bahrani, A. and Bryce, G. and Thomas, M. and Arndt, A.T. and Palazzo, F. and Meguid, R.A. and Fergusson, J. and Beenen, E. and Mosse, C. and Salim, J. and Cheah, S. and Wright, T. and Cerdeira, M.P. and McQuillan, P. and Richardson, M. and Liem, H. and Spillane, J. and Yacob, M. and Albadawi, F. and Thorpe, T. and Dingle, A. and Cabalag, C. and Loi, K. and Fisher, O.M. and Ward, S. and Read, M. and Johnson, M. and Bassari, R. and Bui, H. and Cecco, Predictors of anastomotic leak and conduit necrosis after oesophagectomy: Results from the oesophago-gastric anastomosis audit (OGAA), European Journal of Surgical Oncology, 50, (6), 2024 Journal Article, 2024 DOI

Reynolds, J.V. and Donachie, V. and Marron, J. and Shevlin, A., Management of locally advanced adenocarcinoma of the oesophagus and oesophagogastric junction: the Neo-AEGIS trial â€" Authors' reply, The Lancet Gastroenterology and Hepatology, 9, (2), 2024, p104-105 Journal Article, 2024 DOI

O'Brien, R.M. and Meltzer, S. and Buckley, C.E. and Heeran, A.B. and Nugent, T.S. and Donlon, N.E. and Reynolds, J.V. and Ree, A.H. and Redalen, K.R. and Hafeez, A. and O'Ríordáin, D.S. and Hannon, R.A. and Neary, P. and Kalbassi, R. and Mehigan, B.J. and McCormick, P.H. and Dunne, C. and Kelly, M.E. and Larkin, J.O. and O'Sullivan, J. and Lysaght, J. and Lynam-Lennon, N., Complement is increased in treatment resistant rectal cancer and modulates radioresistance, Cancer Letters, 604, (217253), 2024 Journal Article, 2024 DOI

O'Sullivan, N.J. and Temperley, H.C. and Horan, M.T. and Curtain, B.M.M. and O'Neill, M. and Donohoe, C. and Ravi, N. and Corr, A. and Meaney, J.F.M. and Reynolds, J.V. and Kelly, M.E., Computed tomography (CT) derived radiomics to predict post-operative disease recurrence in gastric cancer; a systematic review and meta-analysis, Current Problems in Diagnostic Radiology, 53, (6), 2024, p717-722 Journal Article, 2024 DOI

Fanning M, Murphy CF, Elliott JA, Ravi N, Docherty NG, le Roux CW, Donohoe CL, Reynolds JV., Continuous glucose monitoring and low-glycaemic index diet in the management of postprandial hypoglycaemia after oesophagogastric cancer surgery., The British journal of surgery, 111, (1), 2024, pznad371 Journal Article, 2024 DOI

Mantziari, S. and Elliott, J.A. and Markar, S.R. and Klevebro, F. and Goense, L. and Johar, A. and Lagergren, P. and Zaninotto, G. and van Hillegersberg, R. and van Berge Henegouwen, M.I. and SchÀfer, M. and Nilsson, M. and Hanna, G.B. and Reynolds, J.V. and Van Veer, H. and Depypere, L. and Coosemans, W. and Nafteux, P. and Carroll, P. and Allison, F. and Darling, G. and Findlay, J.M. and Everden, S. and Maynard, N.D. and Ariyarathenam, A. and Sanders, G. and Jaunoo, S. and Singh, P. and Parsons, S. and Saunders, J. and Vohra, R. and Sinha, A. and Tan, B.H.L. and Whiting, J.G. and Boshier, P.R. and Markar, S.R. and Zaninotto, G. and Hanna, G.B. and Phillips, A.W. and Griffin, S.M. and Walker, R.C. and Underwood, T.J. and Piessen, G. and Theisen, J. and Friess, H. and Bruns, C.J. and Schröder, W. and Collins, C.G. and McAnena, O.J. and Rooney, S. and Quinn, A. and Toale, C. and Murphy, T.J. and Elliott, J.A. and Ravi, N. and Donohoe, C.L. and Reynolds, J.V. and Scarpa, M. and Bardini, R. and Degasperi, S. and Saadeh, L. and Castoro, C. and Alfieri, R. and Pinto, E. and Mattara, G. and Kalff, M.C. and Gisbertz, S.S. and van Hootegem, S.J.M. and Lagarde, S.M. and Kingma, B.F. and Goense, L. and Ruurda, J.P. and van Hillegersberg, R. and Kennedy, R. and Carey, P.D. and Prodehl, L. and Lamb, P.J. and Skipworth, R.J.E. and Dal Cero, M. and Pera, M. and Huang, B. and Klevebro, F. and Nilsson, M. and Johar, A. and Lagergren, P. and Linder, G. and Sundbom, M. and Mantziari, S. and SchÀfer, M. and Demartines, N., Sex-related differences in oncologic outcomes, operative complications and health-related quality of life after curative-intent oesophageal cancer treatment: multicentre retrospective analysis, BJS Open, 8, (2), 2024 Journal Article, 2024 DOI

Mylod E, O'Connell F, Donlon NE, Davern M, Marion C, Butler C, Reynolds JV, Lysaght J, Conroy MJ., Real-time ex vivo monitoring of NK cell migration toward obesity-associated oesophageal adenocarcinoma following modulation of CX3CR1., Scientific reports, 14, (1), 2024, p4017 Journal Article, 2024 DOI

Staunton, L.M. and Bolger, J.C. and Ahmed, R. and Butt, W.T. and Reynolds, J.V. and Ravi, N. and Donohoe, C.L., Reducing recurrence rates in hiatal hernia repair: Results of a quality improvement study, Irish Journal of Medical Science, 2024 Journal Article, 2024 DOI

Wirsik, N.M. and Kooij, C.D. and Dempster, N. and Crnovrsanin, N. and Donlon, N.E. and Uzun, E. and Bhanot, K. and NienhÌser, H. and Polette, D. and Kewani, K. and Grimminger, P. and Reim, D. and Seyfried, F. and Fuchs, H.F. and Gisbertz, S.S. and Germer, C.-T. and Ruurda, J.P. and Klevebro, F. and Schröder, W. and Nilsson, M. and Reynolds, J.V. and Van Berge Henegouwen, M.I. and Markar, S. and Van Hillegersberg, R. and Schmidt, T. and Bruns, C.J., Optimal treatment strategies for cT2 staged adenocarcinoma of the esophagus and the gastroesophageal junction: A multinational, high-volume center retrospective cohort analysis, Annals of Surgery, 2024 Journal Article, 2024 DOI

Gillman A, Kenny C, Hayes M, Walshe M, Reynolds JV, Regan J, Nature, severity, and impact of chronic oropharyngeal dysphagia following curative resection for esophageal cancer: a cross-sectional study., Diseases of the Esophagus., 2024 Journal Article, 2024

Elliott, J.A. and Reynolds, J.V., Insulin resistance, hyperinsulinemia, and cancer: pathogenic considerations and therapeutic opportunities, 2024, 285-314pp Book, 2024 DOI

Morgagni, P. and Bencivenga, M. and Carneiro, F. and Cascinu, S. and Derks, S. and Di Bartolomeo, M. and Donohoe, C. and Eveno, C. and Gisbertz, S. and Grimminger, P. and Gockel, I. and Grabsch, H. and Kassab, P. and Langer, R. and Lonardi, S. and Maltoni, M. and Markar, S. and Moehler, M. and Marrelli, D. and Mazzei, M.A. and Melisi, D. and Milandri, C. and Moenig, P.S. and Mostert, B. and Mura, G. and Polkowski, W. and Reynolds, J. and Saragoni, L. and Van Berge Henegouwen, M.I. and Van Hillegersberg, R. and Vieth, M. and Verlato, G. and Torroni, L. and Wijnhoven, B. and Tiberio, G.A.M. and Yang, H.-K. and Roviello, F. and de Manzoni, G., International consensus on the management of metastatic gastric cancer: step by step in the foggy landscape, Gastric Cancer, 27, (4), 2024, p649-671 Journal Article, 2024 DOI

Dal Cero, M. and Gibert, J. and Grande, L. and Gimeno, M. and Osorio, J. and Bencivenga, M. and Fumagalli Romario, U. and Rosati, R. and Morgagni, P. and Gisbertz, S. and Polkowski, W.P. and Lara Santos, L. and KoÅ'odziejczyk, P. and Kielan, W. and Reddavid, R. and van Sandick, J.W. and Baiocchi, G.L. and Gockel, I. and Davies, A. and Wijnhoven, B.P.L. and Reim, D. and Costa, P. and Allum, W.H. and Piessen, G. and Reynolds, J.V. and Mönig, S.P. and Schneider, P.M. and Garsot, E. and Eizaguirre, E. and Miró, M. and Castro, S. and Miranda, C. and Monzonis-Hernández, X. and Pera, M., International External Validation of Risk Prediction Model of 90-Day Mortality after Gastrectomy for Cancer Using Machine Learning, Cancers, 16, (13), 2024 Journal Article, 2024 DOI

Davern M, O" Donovan C, Donlon NE, Mylod E, Gaughan C, Bhardwaj A, Sheppard AD, Bracken-Clarke D, " Lysaght, J., Conroy, M.J., Analysing the Combined Effects of Radiotherapy and Chemokine Receptor 5 Antagonism: Complementary Approaches to Promote T Cell Function and Migration in Oesophageal Adenocarcinoma., Biomedicines, 2024 Journal Article, 2024 DOI TARA - Full Text

Morgagni, P. and Bencivenga, M. and Carneiro, F. and Cascinu, S. and Derks, S. and Di Bartolomeo, M. and Donohoe, C. and Eveno, C. and Gisbertz, S. and Grimminger, P. and Gockel, I. and Grabsch, H. and Kassab, P. and Langer, R. and Lonardi, S. and Maltoni, M. and Markar, S. and Moehler, M. and Marrelli, D. and Mazzei, M.A. and Melisi, D. and Milandri, C. and Moenig, P.S. and Mostert, B. and Mura, G. and Polkowski, W. and Reynolds, J. and Saragoni, L. and Van Berge Henegouwen, M.I. and Van Hillegersberg, R. and Vieth, M. and Verlato, G. and Torroni, L. and Wijnhoven, B. and Tiberio, G.A.M. and Yang, H.-K. and Roviello, F. and de Manzoni, G. and Allum, W. and Bagnacci, G. and Baiocchi, G.L. and Berlth, F. and Borgno, L. and Yan, J.S.B. and Caccialanza, R. and Casella, F. and Castelli, C. and Chevallay, M. and Corso, S. and Da Costa, P.M. and Dal Cero, M. and De Giuli, M. and De Pascale, S. and Donini, A. and D†Ugo, D. and Ercolani, G. and Filippini, F. and Framarini, M. and Frejlich, E. and Romario, U.F. and Giacopuzzi, S. and Giordano, S. and Graziosi, L. and Hartgrink, H. and Hölscher, A.H. and Kim, J. and Kroese, T. and Gomes, L.L. and Santos, L.L. and Liu, D. and Lordick, F. and Marano, L. and Marino, E. and Martinelli, G. and Meyer, H.-J. and Ministrini, S. and Mansfield, P.F. and Molinari, C. and Monti, M. and Moulla, Y. and Nilsson, M. and Patuzzo, S. and Pera, M. and Castro, O.A.P. and Quinzii, A. and Rapposelli, I.G. and Rausei, S. and Reddavid, R. and Rosa, F. and Rosati, R. and Rossi, R. and Roviello, G. and Rudno-Rudzinska, J. and Sacco, M. and Salati, M. and Schneider, P.M. and Solaini, L. and Terashima, M. and Tomezzoli, A. and Valgiusti, M. and Weston, A.C. and Wojciech, K. and Thortsen, G., Correction: International consensus on the management of metastatic gastric cancer: step by step in the foggy landscape: Bertinoro Workshop, November 2022 (Gastric Cancer, (2024), 27, 4, (649-671), 10.1007/s10120-024-01479-5), Gastric Cancer, 27, (4), 2024, p672-674 Journal Article, 2024 DOI

Henckens, S.P.G. and Schuring, N. and Elliott, J.A. and Johar, A. and Markar, S.R. and Gantxegi, A. and Lagergren, P. and Hanna, G.B. and Pera, M. and Reynolds, J.V. and Van Berge Henegouwen, M.I. and Gisbertz, S.S. and Van Veer, H. and Depypere, L. and Coosemans, W. and Nafteux, P. and Carroll, P. and Allison, F. and Darling, G. and Findlay, J.M. and Everden, S. and Maynard, N.D. and Ariyarathenam, A. and Sanders, G. and Jaunoo, S. and Singh, P. and Parsons, S. and Saunders, J. and Vohra, R. and Sinha, A. and Tan, B.H.L. and Whiting, J.G. and Boshier, P.R. and Markar, S.R. and Zaninotto, G. and Hanna, G.B. and Phillips, A.W. and Griffin, S.M. and Walker, R.C. and Underwood, T.J. and Piessen, G. and Theisen, J. and Friess, H. and Bruns, C.J. and Schröder, W. and Collins, C.G. and McAnena, O.J. and Rooney, S. and Quinn, A. and Toale, C. and Murphy, T.J. and Elliott, J.A. and Ravi, N. and Donohoe, C.L. and Reynolds, J.V. and Scarpa, M. and Bardini, R. and Degasperi, S. and Saadeh, L. and Castoro, C. and Alfieri, R. and Pinto, E. and Mattara, G. and Kalff, M.C. and Gisbertz, S.S. and Van Berge Henegouwen, M.I. and Van Hootegem, S.J.M. and Lagarde, S.M. and Kingma, B.F. and Goense, L. and Ruurda, J.P. and Van Hillegersberg, R. and Kennedy, R. and Carey, P.D. and Prodehl, L. and Lamb, P.J. and Skipworth, R.J.E. and Cero, M.D. and Pera, M. and Huang, B. and Klevebro, F. and Nilsson, M. and Johar, A. and Lagergren, P. and Linder, G. and Sundbom, M. and Mantziari, S. and SchÀfer, M. and Allemann, P. and Demartines, N., Recurrence and Survival after Minimally Invasive and Open Esophagectomy for Esophageal Cancer: A Post Hoc Analysis of the Ensure Study, Annals of Surgery, 280, (2), 2024, p267-273 Journal Article, 2024 DOI

Kroese, T.E. and Bronzwaer, S. and van Rossum, P.S.N. and Schoppman, S.F. and Deseyne, P.R.A.J. and van Cutsem, E. and Haustermans, K. and Nafteux, P. and Thomas, M. and Obermannova, R. and Mortensen, H.R. and Nordsmark, M. and Pfeiffer, P. and Elme, A. and Adenis, A. and Piessen, G. and Bruns, C.J. and Lordick, F. and Gockel, I. and Moehler, M. and Gani, C. and Liakakos, T. and Reynolds, J.V. and Morganti, A.G. and Rosati, R. and Castoro, C. and Cellini, F. and D'Ugo, D. and Roviello, F. and Bencivenga, M. and de Manzoni, G. and van Berge Henegouwen, M.I. and Hulshoff, M.C.C.M. and van Dieren, J. and Vollebergh, M. and van Sandick, J.W. and Jeene, P. and Muijs, C. and Slingerland, M. and Voncken, F.E.M. and Hartgrink, H. and Creemers, G.-J. and van der Sangen, M.J.C. and Nieuwenhuijzen, G.A.P. and Berbee, M. and Verheij, M. and Wijnhoven, B. and Beerepoot, L.V. and Mohammad, N.H. and Mook, S. and Ruurda, J.P. and Kolodziejczyk, P. and Polkowski, W.P. and Wyrwicz, L. and Alsina, M. and Tabernero, J. and Pera, M. and Kanonnikoff, T.F. and Cervantes, A. and Nilsson, M. and Monig, S. and Wagner, A.D. and Guckenberger, M. and Griffiths, E.A. and Smyth, E. and Hanna, G.B. and Markar, S. and Chaudry, M.A. and Hawkins, M.A. and Cheong, E. and van Laarhoven, H.W.M. and van Hillegersberg, R., European clinical practice guidelines for the definition, diagnosis, and treatment of oligometastatic esophagogastric cancer (OMEC-4), European Journal of Cancer, 204, (114062), 2024 Journal Article, 2024 DOI

A. Gillman , M. Hayes, I. Walsh , M. Walshe , J.V. Reynolds & J. Regan, Long-term impact of aerodigestive symptoms on adults with oesophageal cancer: A qualitative study, International Journal of Speech-Language Pathology, 2024 Journal Article, 2024 DOI

O'Neill, S. and Deegan, J. and Ramjit, S. and Reynolds, J.V. and Donohoe, C.L., â€~SurgTalk†: The Educational Outcomes Associated With Development of a Surgical Podcast for Undergraduate Medical Students, Journal of Surgical Education, 81, (2), 2024, p202-209 Journal Article, 2024 DOI

Bennett, A.E., O'Neill, L., Doyle, S.L., Guinan, E.M., O'Sullivan, J., Reynolds, J.V., Hussey, J., Nutrient Intakes and Gastrointestinal Symptoms Among Esophagogastric Cancer Survivors up to 5 Years Post-Surgery, Nutrition and Cancer, 2024, p1-10 Journal Article, 2024 DOI URL

Visser, M.R. and Voeten, D.M. and Gisbertz, S.S. and Ruurda, J.P. and Achiam, M.P. and Nilsson, M. and Markar, S.R. and Pera, M. and Rosati, R. and Piessen, G. and Nafteux, P. and Gutschow, C.A. and Grimminger, P.P. and RÀsÀnen, J.V. and Reynolds, J.V. and Johannessen, H.-O. and Vieira, P. and Weitzendorfer, M. and Kechagias, A. and van Berge Henegouwen, M.I. and van Hillegersberg, R., Western European Variation in the Organization of Esophageal Cancer Surgical Care, Diseases of the Esophagus, 37, (9), 2024 Journal Article, 2024 DOI

Kamaludin, A. and Donlon, N.E. and Kavanagh, M. and Reynolds, J.V. and Donohoe, C.L., Single-center experience in implementation of endoscopic surveillance protocol after esophagectomy, Diseases of the Esophagus, 36, (3), 2023 Journal Article, 2023 DOI

Singh, K. and Liptrot, S. and Tou, S. and Mehigan, B. and McCormick, P. and Ravi, N. and Reynolds, J. and Al Chalabi, H., A multicentre study assessing the role of routine colonoscopy after acute uncomplicated diverticulitis and the incidence of colorectal cancer diagnosis, International Journal of Colorectal Disease, 38, (1), 2023 Journal Article, 2023 DOI

Davern, M. and Bracken-Clarke, D. and Donlon, N.E. and Sheppard, A.D. and Connell, F.O. and Heeran, A.B. and Majcher, K. and Conroy, M.J. and Mylod, E. and Butler, C. and Donohoe, C. and Donnell, D.O. and Lowery, M. and Bhardwaj, A. and Ravi, N. and Melo, A.A. and Sullivan, J.O. and Reynolds, J.V. and Lysaght, J., Visceral adipose tissue secretome from early and late-stage oesophageal cancer patients differentially affects effector and regulatory T cells, Journal of Cancer Research and Clinical Oncology, 2023 Journal Article, 2023 DOI

Reynolds, J.V., Neoadjuvant chemoradiation versus perioperative chemotherapy for oeosphageal adenocarcinoma, British Journal of Surgery, 110, (12), 2023, p1681-1682 Journal Article, 2023 DOI

Temperley, H.C. and Phoenix, E. and Waters, C. and Hanna, J. and Fanning, M. and Donlon, N.E. and Reynolds, J.V. and Donohoe, C.L., Management Experiences of Post-Gastrectomy Severe Alkaline Reflux Esophagitis, American Surgeon, 89, (11), 2023, p5012-5016 Journal Article, 2023 DOI

Kampan, N.C. and Kartikasari, A.E.R. and Deceneux, C. and Madondo, M.T. and McNally, O.M. and Flanagan, K.L. and Aziz, N.A. and Stephens, A.N. and Reynolds, J. and Quinn, M.A. and Plebanski, M., Combining TNFR2-Expressing Tregs and IL-6 as Superior Diagnostic Biomarkers for High-Grade Serous Ovarian Cancer Masses, Cancers, 15, (3), 2023 Journal Article, 2023 DOI

Elliott J., Guinan E., Reynolds J.V, Measurement and optimization of perioperative risk among patients undergoing surgery for esophageal cancer, Diseases of the Esophagus, 2023 Journal Article, 2023

Donlon, N.E. and Davern, M. and Sheppard, A. and O'Connell, F. and Moran, B. and Nugent, T.S. and Heeran, A. and Phelan, J.J. and Bhardwaj, A. and Butler, C. and Ravi, N. and Donohoe, C.L. and Lynam-Lennon, N. and Maher, S. and Reynolds, J.V. and Lysaght, J., Potential of damage associated molecular patterns in synergising radiation and the immune response in oesophageal cancer, World Journal of Gastrointestinal Oncology, 15, (8), 2023, p1349-1365 Journal Article, 2023 DOI

Schuring, N. and Donlon, N.E. and Hagens, E.R.C. and Gootjes, D. and Donohoe, C.L. and van Berge Henegouwen, M.I. and Reynolds, J.V. and Gisbertz, S.S., External validation of a nomogram predicting conditional survival after tri-modality treatment of esophageal cancer, Surgery (United States), 174, (6), 2023, p1363-1370 Journal Article, 2023 DOI

Buckley, C.E. and O†Brien, R.M. and Nugent, T.S. and Donlon, N.E. and O†Connell, F. and Reynolds, J.V. and Hafeez, A. and O†Ríordáin, D.S. and Hannon, R.A. and Neary, P. and Kalbassi, R. and Mehigan, B.J. and McCormick, P.H. and Dunne, C. and Kelly, M.E. and Larkin, J.O. and O†Sullivan, J. and Lynam-Lennon, N., Metformin is a metabolic modulator and radiosensitiser in rectal cancer, Frontiers in Oncology, 13, (1216911), 2023 Journal Article, 2023 DOI

Davern M, Donlon NE, O'Connell F, Gaughan C, O'Donovan C, Habash M, Sheppard AD, MacLean M, Dunne MR, Moore J, Temperley H, Conroy MJ, Butler C, Bhardwaj A, Ravi N, Donohoe CL, Reynolds JV, Lysaght J., Acidosis significantly alters immune checkpoint expression profiles of T cells from oesophageal adenocarcinoma patients, Cancer Immunology Immunotherapy, 2023 Journal Article, 2023 TARA - Full Text DOI

Gujjuri RR, Clarke JM, Elliott JA, Rahman SA, Reynolds JV, Hanna GB, Markar SR, ENSURE Group Study., Predicting long-term survival and time-to-recurrence after esophagectomy in patients with esophageal cancer - Development and validation of a multivariate prediction model., Annals of surgery, 277, (6), 2023, p971-978 Journal Article, 2023 DOI

Moran B, Davern M, Reynolds JV, Donlon NE, Lysaght J., The impact of histone deacetylase inhibitors on immune cells and implications for cancer therapy, Cancer Letters, 2023 Journal Article, 2023 DOI

Davern, M. and Gaughan, C. and O†Connell, F. and Moran, B. and Mylod, E. and Sheppard, A.D. and Ramjit, S. and Yun-Tong Kung, J. and Phelan, J.J. and Davey, M.G. and Ryan, E.J. and Butler, C. and Quinn, L. and Howard, C. and Tone, E. and Phoenix, E. and Butt, W.T. and Lynam-Lennon, N. and Maher, S.G. and Ravi, N. and Donohoe, C.L. and Reynolds, J.V. and Lysaght, J. and Donlon, N.E., PD-1 blockade attenuates surgery-mediated immunosuppression and boosts Th1 immunity perioperatively in oesophagogastric junctional adenocarcinoma, Frontiers in Immunology, 14, (1150754), 2023 Journal Article, 2023 DOI

Elliott JA, Markar SR, Klevebro F, Johar A, Goense L, Lagergren P, Zaninotto G, van Hillegersberg R, van Berge Henegouwen MI, Nilsson M, Hanna GB, Reynolds JV, ENSURE Study Group., An International Multicenter Study Exploring Whether Surveillance After Esophageal Cancer Surgery Impacts Oncological and Quality of Life Outcomes (ENSURE)., Annals of surgery, 277, (5), 2023, pe1035-e1044 Journal Article, 2023 DOI

O'Carroll, J.E. and Zucco, L. and Warwick, E. and Arbane, G. and Moonesinghe, S.R. and El-Boghdadly, K. and Guo, N. and Carvalho, B. and Sultan, P. and Abayasinghe, C. and Abeywardana, C. and Adams, L. and Aduse-Poku, M. and Agarwal, M. and Ahmed, D. and Ahuja, P. and Ali, H. and Allen, G. and Aly, H. and Anderson, H. and Annamalai, P. and Appiah, S. and Arbane, G. and Arch, A. and Armstrong, S. and Ashraf, A. and Athorn-Wright, D. and Atkinson, R. and Austin, L. and Badal, B. and Bajaj, S. and Baker, M. and Balogun, O. and Bampoe, S. and Banni, D. and Barnes, H. and Barnes, L. and Barot, N. and Barr, R. and Bassi, R. and Baxendale, L. and Beadle, S. and Beard, H. and Beatty, F. and Beeby, S. and Bell, J. and Bell, S. and Benlloch, R. and Benn, T. and Bennett, H. and Beranova, E. and Berry, S. and Bethell, H. and Bhatia, K. and Bhattacharyya, S. and Bhattari, B. and Bhimanaboina, R. and Bigwood, M. and Bircham, S. and Biss, J. and Bland, J. and Blightman, O. and Botchway, P. and Bouras, L. and Bowditch, J. and Boyle, H. and Bradshaw, M. and Brady, L. and Brain, J. and Brathwaite-Shirley, C. and Brayshaw, S. and Bressington, C. and Brewer, F. and Bromley, D. and Brown, E. and Brown, J. and Brown, N. and Brown, B. and Bruynseels, D. and Buckley, R. and Bukowska, I. and Burnard, S. and Burnell, R. and Burnish, R. and Busby, C. and Butler, J. and Camburn, T. and Campbell, R. and Campbell, N. and Canclini, L. and Cannons, V. and Cantliffe, J. and Carey, A. and Carpenter, J. and Carpenter, J. and Carrington, R. and Carta, S. and Cassin, R. and Castle, G. and Chadderton, I. and Chadwick, K. and Challifour, C. and Cheong, K. and Cherian-McIvor, V. and Chirvasuta, R. and Christmas, T. and Christopolou, A. and Clarey, E. and Cochran, D. and Coker, N. and Colhoun, A. and Colling, K. and Collins, E. and Collins, J. and Collins, V. and Colville, G. and Connelly, S. and Connolly, A. and Conolloy, K. and Cooper, C. and Cope, S. and Coppel, J. and Cormack, C. and Cortaville, R. and Cottam, D. and Cotterell, S. and Cousins, S. and Coutts, P. and Cowan, A. and Craig, C. and Crail, C. and Critchley, J. and Crosby, R. and Cross, C. and Crossingham, G. and Crossland, C. and Cervera, T.C. and Cummin, O. and Curtis, S. and Cusick, S. and Das, A. and Davenport, G. and David, X. and Davies, R. and Davies, J. and Davies, H. and de la Iglesia, C. and Dean, T. and Dearden, J. and Death, K. and Deery, J. and Denford, C. and Derby, E. and Desai, J. and Diaz, C. and Dissanayake, M. and Dixon, C. and Doleman, B. and Donlon, S. and Dooks, E. and Downs, B. and Duckham, E. and Dudhill, H. and Dunning, J. and Eka, I. and Eke, Z. and Elam, L. and Elfaioumy, A. and Ellis, R. and Ellis, C. and Ellison, A. and Elton, C. and Endersby, D. and Essien, S. and Evans, K. and Evans, J. and Evans, L. and Finlay, E. and Finn, J. and Fishwick, R. and Fisk, S. and Flood, O. and Fludder, V. and Flynn-Batham, M. and Flynn-Batham, M. and Foreman, K. and Forsey, M. and Foulds, A. and Fox, C. and Freeman, N. and Fronda, R. and Froud, O. and Fulton, L. and Gaines, M. and Gallop, F. and Garden, L. and Garnder, A. and Garner, Z. and Garvey, G. and Gautam, N. and Gavin, J. and Gentle, L. and Gerth, A. and Goel, R. and Gohil, B. and Goodman, B. and Gosal, A. and Gott, E. and Gowans, S. and Graham, C., Quality of recovery following childbirth: a prospective, multicentre cohort study, Anaesthesia, 78, (9), 2023, p1071-1080 Journal Article, 2023 DOI

Temperley, H.C. and Davey, M.G. and O'Sullivan, N.J. and Ryan, Ã .J. and Donlon, N.E. and Donohoe, C.L. and Reynolds, J.V., What works best in hiatus hernia repair, sutures alone, absorbable mesh or non-absorbable mesh? A systematic review and network meta-analysis of randomized clinical trials, Diseases of the Esophagus, 36, (7), 2023 Journal Article, 2023 DOI

McDonnell, S. and Breslin, T. and Mascan, B. and Shahruddin, N.S. and Elnour, M. and Fanning, M. and Galvin, A. and Moore, J. and Ravi, N. and Reynolds, J.V. and Donohoe, C.L., Translating evidence in a priority setting partnership: knowledge gaps between healthcare providers and oesophageal cancer patients, Supportive Care in Cancer, 31, (2), 2023 Journal Article, 2023 DOI

Elliott JA, Klevebro F, Mantziari S, Markar SR, Goense L, Johar A, Lagergren P, Zaninotto G, van Hillegersberg R, van Berge Henegouwen MI, Schäfer M, Nilsson M, Hanna GB, Reynolds JV, ENSURE Study Group., Neoadjuvant Chemoradiotherapy Versus Chemotherapy for the Treatment of Locally Advanced Esophageal Adenocarcinoma in the European Multicenter ENSURE Study., Annals of surgery, 278, (5), 2023, p692-700 Journal Article, 2023 DOI

Wirsik, N.M. and Schmidt, T. and NienhÌser, H. and Donlon, N.E. and De Jongh, C. and Uzun, E. and Fuchs, H.F. and Brunner, S. and Alakus, H. and Hölscher, A.H. and Grimminger, P. and Schneider, M. and Reynolds, J.V. and Van Hillegersberg, R. and Bruns, C.J., Impact of the Surgical Approach for Neoadjuvantly Treated Gastroesophageal Junction Type II Tumors: A Multinational, High-volume Center Retrospective Cohort Analysis, Annals of Surgery, 278, (5), 2023, p683-691 Journal Article, 2023 DOI

Reynolds, J.V. and Preston, S.R. and O'Neill, B. and Lowery, M.A. and Baeksgaard, L. and Crosby, T. and Cunningham, M. and Cuffe, S. and Griffiths, G.O. and Parker, I. and Risumlund, S.L. and Roy, R. and Falk, S. and Hanna, G.B. and Bartlett, F.R. and Alvarez-Iglesias, A. and Achiam, M.P. and Nilsson, M. and Piessen, G. and Ravi, N. and O'Toole, D. and Johnston, C. and McDermott, R.S. and Turkington, R.C. and Wahed, S. and Sothi, S. and Ford, H. and Wadley, M.S. and Power, D. and Mukherjee, S. and Morgan, C. and Parsons, S.L. and Bhuva, N. and Campbell, S. and Grogan, L. and Leonard, G. and Bateman, A.R. and Mitchell, C. and O'Reilly, S. and Mulroe, E. and McLoughlin, O. and Shevlin, A. and Shannon, A.M. and Marron, J. and Nolan, M. and Burch, G. and Costello, M. and Griffiths, D. and Cozens, K. and Foley, E. and Donohoe, C.L. and O'Farrell, C. and Moore, J. and O'Sullivan, J., Trimodality therapy versus perioperative chemotherapy in the management of locally advanced adenocarcinoma of the oesophagus and oesophagogastric junction (Neo-AEGIS): an open-label, randomised, phase 3 trial, The Lancet Gastroenterology and Hepatology, 8, (11), 2023, p1015-1027 Journal Article, 2023 DOI

Kroese, T.E. and van Laarhoven, H.W.M. and Schoppman, S.F. and Deseyne, P.R.A.J. and van Cutsem, E. and Haustermans, K. and Nafteux, P. and Thomas, M. and Obermannova, R. and Mortensen, H.R. and Nordsmark, M. and Pfeiffer, P. and Elme, A. and Adenis, A. and Piessen, G. and Bruns, C.J. and Lordick, F. and Gockel, I. and Moehler, M. and Gani, C. and Liakakos, T. and Reynolds, J. and Morganti, A.G. and Rosati, R. and Castoro, C. and Cellini, F. and D'Ugo, D. and Roviello, F. and Bencivenga, M. and de Manzoni, G. and van Berge Henegouwen, M.I. and Hulshof, M.C.C.M. and van Dieren, J. and Vollebergh, M. and van Sandick, J.W. and Jeene, P. and Muijs, C.T. and Slingerland, M. and Voncken, F.E.M. and Hartgrink, H. and Creemers, G.-J. and van der Sangen, M.J.C. and Nieuwenhuijzen, G. and Berbee, M. and Verheij, M. and Wijnhoven, B. and Beerepoot, L.V. and Mohammad, N.H. and Mook, S. and Ruurda, J.P. and Kolodziejczyk, P. and Polkowski, W.P. and Wyrwicz, L. and Alsina, M. and Pera, M. and Kanonnikoff, T.F. and Cervantes, A. and Nilsson, M. and Monig, S. and Wagner, A.D. and Guckenberger, M. and Griffiths, E.A. and Smyth, E. and Hanna, G.B. and Markar, S. and Chaudry, M.A. and Hawkins, M.A. and Cheong, E. and van Hillegersberg, R. and van Rossum, P.S.N. and Rozema, T. and Heisterkamp, J. and Schaefer, M. and Ozsahin, E.-M. and de Haan, J. and Willem van den Berg, J. and Duprez, F. and Callebout, E. and van Daele, E. and Hacker, U. and Hoffmeister, A. and Kuhnt, T. and Denecke, T. and Kluge, R. and Prager, G. and Ilhan-Mutlu, A. and Cuicchi, D. and Ardizzoni, A. and Rosman, C. and Gootjes, E.C. and RÃŒtten, H. and Puccetti, F. and Cascinu, S. and Slim, N. and Barrios, M.E. and Fernandez, M.C. and Martí-Oriol, R. and Alvaro, M.H. and Vera, A. and Jordá, E. and Mozos, F.L. and Reig, A. and Visa, L. and CiseÅ', B. and Czechowska, J. and Kwietniewska, M. and PikuÅ'a, A. and Skórzewska, M. and KozÅ'owska, A. and Rawicz-PruszyÅ"ski, K., Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer: A Delphi consensus study in Europe, European Journal of Cancer, 185, 2023, p28-39 Journal Article, 2023 DOI

Ubels, S. and Matthée, E. and Verstegen, M. and Klarenbeek, B. and Bouwense, S. and van Berge Henegouwen, M.I. and Daams, F. and Dekker, J.W.T. and van Det, M.J. and van Esser, S. and Griffiths, E.A. and Haveman, J.W. and Nieuwenhuijzen, G. and Siersema, P.D. and Wijnhoven, B. and Hannink, G. and van Workum, F. and Rosman, C. and Heisterkamp, J. and Polat, F. and Schouten, J. and Singh, P. and Slootmans, C.A.M. and Ultee, G. and Gisbertz, S.S. and Eshuis, W.J. and Kalff, M.C. and Feenstra, M.L. and van der Peet, D.L. and Stam, W.T. and Van Etten, B. and Poelmann, F. and Vuurberg, N. and Willem van den Berg, J. and Martijnse, I.S. and Matthijsen, R.M. and Luyer, M. and Curvers, W. and Nieuwenhuijzen, T. and Taselaar, A.E. and Kouwenhoven, E.A. and Lubbers, M. and Sosef, M. and Lecot, F. and Geraedts, T.C.M. and van den Wildenberg, F. and Kelder, W. and Baas, P.C. and de Haas, J.W.A. and Hartgrink, H.H. and Bahadoer, R.R. and van Sandick, J.W. and Hartemink, K.J. and Veenhof, X. and Stockmann, H. and Gorgec, B. and Weeder, P. and Wiezer, M.J. and Genders, C.M.S. and Belt, E. and Blomberg, B. and van Duijvendijk, P. and Claassen, L. and Reetz, D. and Steenvoorde, P. and Mastboom, W. and Klein Ganseij, H.J. and van Dalsen, A.D. and Joldersma, A. and Zwakman, M. and Groenendijk, R.P.R. and Montazeri, M. and Mercer, S. and Knight, B. and van Boxel, G. and McGregor, R.J. and Skipworth, R.J.E. and Frattini, C. and Bradley, A. and Nilsson, M. and Hayami, M. and Huang, B. and Bundred, J. and Evans, R. and Grimminger, P.P. and van der Sluis, P.C. and Eren, U. and Saunders, J. and Theophilidou, E. and Khanzada, Z. and Elliott, J.A. and Ponten, J. and King, S. and Reynolds, J.V. and Sgromo, B. and Akbari, K. and Shalaby, S. and Gutschow, C.A. and Schmidt, H. and Vetter, D. and Moorthy, K. and Ibrahim, M.A.H. and Christodoulidis, G. and RÀsÀnen, J.V. and Kauppi, J. and Söderström, H. and Koshy, R. and Manatakis, D.K. and Korkolis, D.P. and Balalis, D. and Rompu, A. and Alkhaffaf, B. and Alasmar, M. and Arebi, M. and Piessen, G. and Nuytens, F. and Degisors, S. and Ahmed, A. and Boddy, A. and Gandhi, S. and Fashina, O. and Van Daele, E. and Pattyn, P. and Robb, W.B. and Arumugasamy, M. and Al Azzawi, M. and Whooley, J. and Colak, E. and Aybar, E. and Sari, A.C. and Uyanik, M.S. and Ciftci, A.B. and Sayyed, R. and Ayub, B. and Murtaza, G. and Saeed, A. and Ramesh, P. and Charalabopoulos, A. and Liakakos, T. and Schizas, D. and Baili, E. and Kapelouzou, A. and Valmasoni, M. and Pierobon, E.S. and Capovilla, G. and Merigliano, S. and Constantinoiu, S. and Birla, R. and Achim, F. and Rosianu, C.G. and Hoara, P. and Castro, R.G. and Salcedo, A.F. and Negoi, I. and Negoita, V.M. and Ciubotaru, C. and Stoica, B. and Hostiuc, S. and Colucci, N. and Mönig, S.P. and Wassmer, C.-H. and Meyer, J. and Takeda, F.R. and Aissar Sallum, R.A. and Ribeiro, U. and Cecconello, I. and Toledo, E. and Trugeda, M.S. and Fernández, M.J. and Gil, C. and Castanedo, S. and Isik, A. and Kurnaz, E. and Videira, J.F. and Peyroteo, M. and Canotilho, R. and Weindelmayer, J. and Giacopuzzi, S. and De Pasqual, C.A. and Bruna, M. and Mingol, F. and Vaque, J. and Pérez, C. and Phillips, A.W. and Chmelo, J. and Brown, J. and Han, L.E. and Gossage, J.A. and Davies, A.R. and Baker, C.R. , Erratum to †Practice variation in anastomotic leak after esophagectomy: Unravelling differences in failure to rescue†[Eur J Surg Oncol 49 (5) (May 2023) 974â€"982](S074879832300032X)(10.1016/j.ejso.2023.01.010), European Journal of Surgical Oncology, 49, (9), 2023 Journal Article, 2023 DOI

O'Brien, A., Brennan, L., O'Neill, L, Guinan, E., Connolly, D., Reynolds, JV., and Hussey, J., Patient Experiences of a Telehealth Multidisciplinary Cancer Rehabilitation Programme: Qualitative Findings from the ReStOre@Home Feasibility Study, 2023 Journal Article, 2023 DOI

Ubels S, Matthée E, Verstegen M, Klarenbeek B, Bouwense S, van Berge Henegouwen MI, Daams F, Dekker JWT, van Det MJ, van Esser S, Griffiths EA, Haveman JW, Nieuwenhuijzen G, Siersema PD, Wijnhoven B, Hannink G, van Workum F, Rosman C, TENTACLE " Esophagus collaborative group, Writing Committee, Heisterkamp J, Polat F, Schouten J, Singh P, Study collaborators., Practice variation in anastomotic leak after esophagectomy: Unravelling differences in failure to rescue., European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 49, (5), 2023, p974-982 Journal Article, 2023 DOI

Ubels S, Verstegen MHP, Klarenbeek BR, Bouwense S, van Berge Henegouwen MI, Daams F, van Det MJ, Griffiths EA, Haveman JW, Heisterkamp J, Nieuwenhuijzen G, Polat F, Schouten J, Siersema PD, Singh P, Wijnhoven B, Hannink G, van Workum F, Rosman C, TENTACLE"Esophagus Collaborative Group., Treatment of anastomotic leak after oesophagectomy for oesophageal cancer: large, collaborative, observational TENTACLE cohort study., The British journal of surgery, 110, (7), 2023, p852-863 Journal Article, 2023 DOI

Steering Committee and Alderson, D. and Bundred, J. and Rpt, E. and Gossage, J. and Griffiths, E.A. and Jefferies, B. and Kamarajah, S.K. and McKay, S. and Mohamed and Nepogodiev, D. and Siaw- Acheampong, K. and Singh, P. and Van Hillegersberg, R. and Vohra, R. and Wanigasooriya, K. and Whitehouse, T. and National Leads and Gjata, A. and Moreno, J.I. and Takeda, F.R. and Kidane, B. and Guevara Castro, R. and Harustiak, T. and Bekele, A. and Kechagias, A. and Gockel and Kennedy, A. and Da Roit, A. and Bagajevas, A. and Azagra, J.S. and Mahendran, H.A. and Mejía-Fernández, L. and Wijnhoven, B.P.L. and El Kafsi, J. and Sayyed, R.H. and Sousa, M. and Sampaio, A.S. and Negoi and Blanco, R. and Wallner, B. and Schneider, P.M. and Hsu, P.K. and Isik, A. and Leads, S. and Gananadha, S. and Wills and Devadas, M. and Duong, C. and Talbot, M. and Hii, M.W. and Jacobs, R. and Andreollo, N.A. and Johnston, B. and Darling, G. and Isaza-Restrepo, A. and Rosero, G. and Arias-Amézquita, F. and Raptis, D. and Gaedcke, J. and Reim, D. and Izbicki, J. and Egberts, J.H. and Dikinis, S. and Kjaer, D.W. and Larsen, M.H. and Achiam, M.P. and Saarnio, J. and Theodorou, D. and Liakakos, T. and Korkolis, D.P. and Robb, W.B. and Collins, C. and Murphy, T. and Reynolds, J. and Tonini and Migliore, M. and Bonavina, L. and Valmasoni, M. and Bardini, R. and Weindelmayer, J. and Terashima, M. and White, R.E. and Alghunaim, E. and Elhadi, M. and Leon-Takahashi, A.M. and Medina-Franco, H. and Lau, P.C. and Okonta, K.E. and Heisterkamp, J. and Rosman, C. and Van Hillegersberg, R. and Beban, G. and Babor, R. and Gordon, A. and Rossaak, J.I. and Pal, K.M.I. and Qureshi, A.U. and Naqi, S.A. and Syed, A.A. and Barbosa, J. and Vicente, C.S. and Leite, J. and Freire, J. and Casaca, R. and Costa, R.C.T. and Scurtu, R.R. and Mogoanta, S.S. and Bolca, C. and Constantinoiu, S. and Sekhniaidze, D. and BjeloviÄ , M. and So, J.B.Y. and GaÄ evski, G. and Loureiro, C. and Pera, M. and Bianchi, A. and Moreno Gijón, M. and Martín Fernández, J. and Trugeda Carrera, M.S. and Vallve-Bernal, M. and Cítores Pascual, M.A. and Elmahi, S. and Halldestam and Hedberg, J. and Mönig, S. and Gutknecht, S. and Tez, M. and Guner, A. and Tirnaksiz, M.B. and Colak, E. and Sevinç, B. and Hindmarsh, A. and Khan and Khoo, D. and Byrom, R. and Gokhale, J. and Wilkerson, P. and Jain, P. and Chan, D. and Robertson, K. and Iftikhar, S. and Skipworth, R. and Forshaw, M. and Higgs, S. and Gossage, J. and Nijjar, R. and Viswanath, Y.K.S. and Turner, P. and Dexter, S. and Boddy, A. and Allum, W.H. and Oglesby, S. and Cheong, E. and Beardsmore, D. and Vohra, R. and Maynard, N. and Berrisford, R. and Mercer, S. and Puig, S. and Melhado, R. and Kelty, C. and Underwood, T. and Dawas, K. and Lewis, W. and Al-Bahrani, A. and Bryce, G. and Thomas, M. and Arndt, A.T. and Palazzo, F. and Meguid, R.A. and Collaborators and Fergusson, J. and Beenen, E. and Mosse, C. and Salim, J. and Cheah, S. and Wright, T. and Cerdeira, M.P. and McQuillan, P. and Richardson, M. and Liem, H. and Spillane, J. and Yacob, M. and Albadawi, F. and Thorpe, T. and Dingle, A. and Cabalag, C. and Loi, K. and Fisher, O.M. and Ward, S. and Read, M. and Johnson, M. and Bassari, R. and Bui, H. and Cecconello and Raa, S. and Da Rocha, J.R.M. and Lopes, Postoperative and Pathological Outcomes of CROSS and FLOT as Neoadjuvant Therapy for Esophageal and Junctional Adenocarcinoma: An International Cohort Study From the Oesophagogastric Anastomosis Audit (OGAA), Annals of Surgery, 277, (5), 2023, pE1026-E1034 Journal Article, 2023 DOI

O†Connell, F. and Mylod, E. and Donlon, N.E. and Heeran, A.B. and Butler, C. and Bhardwaj, A. and Ramjit, S. and Durand, M. and Lambe, G. and Tansey, P. and Welartne, I. and Sheahan, K.P. and Yin, X. and Donohoe, C.L. and Ravi, N. and Dunne, M.R. and Brennan, L. and Reynolds, J.V. and Roche, H.M. and O†Sullivan, J., Energy Metabolism, Metabolite, and Inflammatory Profiles in Human Ex Vivo Adipose Tissue Are Influenced by Obesity Status, Metabolic Dysfunction, and Treatment Regimes in Patients with Oesophageal Adenocarcinoma, Cancers, 15, (6), 2023 Journal Article, 2023 DOI

Cools-Lartigue, J. and Markar, S. and Mueller, C. and Hofstetter, W. and Nilsson, M. and Ilonen, I. and Soderstrom, H. and Rasanen, J. and Gisbertz, S. and Hanna, G.B. and Elliott, J. and Reynolds, J. and Kisiel, A. and Griffiths, E. and Van Berge Henegouwen, M. and Ferri, L., An International Cohort Study of Prognosis Associated With Pathologically Complete Response Following Neoadjuvant Chemotherapy Versus Chemoradiotherapy of Surgical Treated Esophageal Adenocarcinoma, Annals of surgery, 276, (5), 2022, p799-805 Journal Article, 2022 DOI

Donlon, N.E. and Moran, B. and Kamilli, A. and Davern, M. and Sheppard, A. and King, S. and Donohoe, C.L. and Lowery, M. and Cunningham, M. and Ravi, N. and Mueller, C. and Cools-Lartigue, J. and Ferri, L. and Reynolds, J.V., CROSS Versus FLOT Regimens in Esophageal and Esophagogastric Junction Adenocarcinoma: A Propensity-Matched Comparison, Annals of surgery, 276, (5), 2022, p792-798 Journal Article, 2022 DOI

Davern, M. and O†Brien, R.M. and McGrath, J. and Donlon, N.E. and Melo, A.M. and Buckley, C.E. and Sheppard, A.D. and Reynolds, J.V. and Lynam-Lennon, N. and Maher, S.G. and Lysaght, J., PD-1 blockade enhances chemotherapy toxicity in oesophageal adenocarcinoma, Scientific Reports, 12, (1), 2022 Journal Article, 2022 DOI

Noel E. Donlon, Maria Davern, Andrew D. Sheppard, Fiona O'Connell, Margaret R. Dunne, Conall Hayes, Eimear Mylod, Sinead Ramjit, Hugo Temperley, Michael Mac Lean, Gillian Cotter, Anshul Bhardwaj, Christine Butler, Melissa J. Conroy, Jacintha O'Sullivan, Narayanasamy Ravi, Claire L. Donohoe, John V. Reynolds and Joanne Lysaght, The Impact of Esophageal Oncological Surgery on Perioperative Immune Function; Implications for Adjuvant Immune Checkpoint Inhibition, Frontiers in Immunology, 2022 Journal Article, 2022 URL

Davern, M. and Donlon, N.E. and O†Connell, F. and Sheppard, A.D. and Hayes, C. and King, R. and Temperley, H. and Butler, C. and Bhardwaj, A. and Moore, J. and Bracken-Clarke, D. and Donohoe, C. and Ravi, N. and Reynolds, J.V. and Maher, S.G. and Conroy, M.J. and Lysaght, J., Cooperation between chemotherapy and immune checkpoint blockade to enhance anti-tumour T cell immunity in oesophageal adenocarcinoma, Translational Oncology, 20, (101406), 2022 Journal Article, 2022 DOI

Gillman A, Hayes M; Sheaf G, Walshe M, Reynolds JV, Regan J, Exercise-Based Dysphagia Rehabilitation for Adults with Oesophageal Cancer: a Systematic Review, BMC Cancer, 2022 Journal Article, 2022 TARA - Full Text URL DOI

Mylod, E. and O†connell, F. and Donlon, N.E. and Butler, C. and Reynolds, J.V. and Lysaght, J. and Conroy, M.J., The omentum in obesity-associated cancer: A hindrance to effective natural killer cell migration towards tumour which can be overcome by cx3cr1 antagonism, Cancers, 14, (1), 2022 Journal Article, 2022 DOI

Cools-Lartigue, J. and Markar, S. and Mueller, C. and Hofstetter, W. and Nilsson, M. and Ilonen, I. and Soderstrom, H. and Rasanen, J. and Gisbertz, S. and Hanna, G.B. and Elliott, J. and Reynolds, J. and Kisiel, A. and Griffiths, E. and van Berge Henegouwen, M. and Ferri, L., An international cohort study of prognosis associated with pathologically complete response following neoadjuvant chemotherapy versus chemoradiotherapy of surgical treated esophageal adenocarcinoma, Annals of Surgery, 276, (5), 2022, p799-805 Journal Article, 2022 DOI

Ubels, S. and Lubbers, M. and Verstegen, M.H.P. and Bouwense, S.A.W. and van Daele, E. and Ferri, L. and Gisbertz, S.S. and Griffiths, E.A. and Grimminger, P. and Hanna, G. and Hubka, M. and Law, S. and Low, D. and Luyer, M. and Merritt, R.E. and Morse, C. and Mueller, C.L. and Nieuwenhuijzen, G.A.P. and Nilsson, M. and Reynolds, J.V. and Ribeiro, U. and Rosati, R. and Shen, Y. and Wijnhoven, B.P.L. and Klarenbeek, B.R. and van Workum, F. and Rosman, C., Treatment of anastomotic leak after esophagectomy: insights of an international case vignette survey and expert discussions, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 35, (12), 2022 Journal Article, 2022 DOI

Bolger, J.C. and Donohoe, C.L. and Lowery, M. and Reynolds, J.V., Advances in the curative management of oesophageal cancer, British Journal of Cancer, 126, (5), 2022, p706-717 Journal Article, 2022 DOI

Gillman A, Hayes M; Sheaf G, Walshe M, Reynolds JV, Regan J, Exercise-Based Dysphagia Rehabilitation for Adults with Oesophageal Cancer: a Systematic Review, Dysphagia, 10th ESSD Congress, 2020, 2022 Published Abstract, 2022 DOI

Bolger, J.C. and Donlon, N.E. and Butt, W. and Neary, C. and Al Azzawi, M. and Brett, O. and King, S. and Downey, E. and Arumugasamy, M. and Murphy, T. and Robb, W.B. and Collins, C.G. and Carroll, P.A. and Donohoe, C.L. and Ravi, N. and Reynolds, J.V., Successful maintenance of process and outcomes for oesophageal cancer surgery in Ireland during the first wave of the COVID-19 pandemic, Irish Journal of Medical Science, 191, (2), 2022, p831-837 Journal Article, 2022 DOI

Schuring, N. and Jezerskyte, E. and van Berge Henegouwen, M.I. and Sprangers, M.A.G. and Lagergren, P. and Johar, A. and Markar, S.R. and Gisbertz, S.S. and Markar, S.R. and Zaninotto, G. and Castoro, C. and Johar, A. and Lagergren, P. and Elliott, J.A. and Gisbertz, S.S. and Mariette, C. and Alfieri, R. and Huddy, J. and Sounderajah, V. and Pinto, E. and Scarpa, M. and Klevebro, F. and Sunde, B. and Murphy, C.F. and Greene, C. and Ravi, N. and Piessen, G. and Brenkman, H. and Ruurda, J.P. and Hillegersberg, R.V. and Lagarde, S. and Wijnhoven, B. and Pera, M. and Roig, J. and Castro, S. and Matthijsen, R. and Findlay, J. and Antonowicz, S. and Maynard, N. and McCormack, O. and Ariyarathenam, A. and Sanders, G. and Cheong, E. and Jaunoo, S. and Allum, W. and Lanschot, J.V. and Nilsson, M. and Reynolds, J.V. and van Berge Henegouwen, M.I. and Hanna, G.B., Influence of postoperative complications following esophagectomy for cancer on quality of life: A European multicenter study, European Journal of Surgical Oncology, 2022 Journal Article, 2022 DOI

Donlon, N.E. and Moran, B. and Kamilli, A. and Davern, M. and Sheppard, A. and King, S. and Donohoe, C.L. and Lowery, M. and Cunningham, M. and Ravi, N. and Mueller, C. and Cools-Lartigue, J. and Ferri, L. and Reynolds, J.V., Cross versus flot regimens in esophageal and esophagogastric junction adenocarcinoma a propensity-matched comparison, Annals of Surgery, 276, (5), 2022, p792-798 Journal Article, 2022 DOI

Kamarajah, S.K. and Evans, R.P.T. and Nepogodiev, D. and Hodson, J. and Bundred, J.R. and Gockel, I. and Gossage, J.A. and Isik, A. and Kidane, B. and Mahendran, H.A. and Negoi, I. and Okonta, K.E. and Sayyed, R. and van Hillegersberg, R. and Vohra, R.S. and Wijnhoven, B.P.L. and Singh, P. and Griffiths, E.A. and Kamarajah, S.K. and Hodson, J. and Griffiths, E.A. and Alderson, D. and Bundred, J. and Evans, R.P.T. and Gossage, J. and Griffiths, E.A. and Jefferies, B. and Kamarajah, S.K. and McKay, S. and Mohamed, I. and Nepogodiev, D. and Siaw-Acheampong, K. and Singh, P. and van Hillegersberg, R. and Vohra, R. and Wanigasooriya, K. and Whitehouse, T. and Gjata, A. and Moreno, J.I. and Takeda, F.R. and Kidane, B. and Guevara Castro, R. and Harustiak, T. and Bekele, A. and Kechagias, A. and Gockel, I. and Kennedy, A. and Da Roit, A. and Bagajevas, A. and Azagra, J.S. and Mahendran, H.A. and Mejía-Fernández, L. and Wijnhoven, B.P.L. and El Kafsi, J. and Sayyed, R.H. and Sousa, M. and Sampaio, A.S. and Negoi, I. and Blanco, R. and Wallner, B. and Schneider, P.M. and Hsu, P.K. and Isik, A. and Gananadha, S. and Wills, V. and Devadas, M. and Duong, C. and Talbot, M. and Hii, M.W. and Jacobs, R. and Andreollo, N.A. and Johnston, B. and Darling, G. and Isaza-Restrepo, A. and Rosero, G. and Arias-Amézquita, F. and Raptis, D. and Gaedcke, J. and Reim, D. and Izbicki, J. and Egberts, J.H. and Dikinis, S. and Kjaer, D.W. and Larsen, M.H. and Achiam, M.P. and Saarnio, J. and Theodorou, D. and Liakakos, T. and Korkolis, D.P. and Robb, W.B. and Collins, C. and Murphy, T. and Reynolds, J. and Tonini, V. and Migliore, M. and Bonavina, L. and Valmasoni, M. and Bardini, R. and Weindelmayer, J. and Terashima, M. and White, R.E. and Alghunaim, E. and Elhadi, M. and Leon-Takahashi, A.M. and Medina-Franco, H. and Lau, P.C. and Okonta, K.E. and Heisterkamp, J. and Rosman, C. and van Hillegersberg, R. and Beban, G. and Babor, R. and Gordon, A. and Rossaak, J.I. and Pal, K.M.I. and Qureshi, A.U. and Naqi, S.A. and Syed, A.A. and Barbosa, J. and Vicente, C.S. and Leite, J. and Freire, J. and Casaca, R. and Costa, R.C.T. and Scurtu, R.R. and Mogoanta, S.S. and Bolca, C. and Constantinoiu, S. and Sekhniaidze, D. and BjeloviÄ , M. and So, J.B.Y. and GaÄ evski, G. and Loureiro, C. and Pera, M. and Bianchi, A. and Moreno Gijón, M. and Martín Fernández, J. and Trugeda Carrera, M.S. and Vallve-Bernal, M. and Cítores Pascual, M.A. and Elmahi, S. and Halldestam, I. and Hedberg, J. and Mönig, S. and Gutknecht, S. and Tez, M. and Guner, A. and Tirnaksiz, M.B. and Colak, E. and Sevinç, B. and Hindmarsh, A. and Khan, I. and Khoo, D. and Byrom, R. and Gokhale, J. and Wilkerson, P. and Jain, P. and Chan, D. and Robertson, K. and Iftikhar, S. and Skipworth, R. and Forshaw, M. and Higgs, S. and Gossage, J. and Nijjar, R. and Viswanath, Y.K.S. and Turner, P. and Dexter, S. and Boddy, A. and Allum, W.H. and Oglesby, S. and Cheong, E. and Beardsmore, D. and Vohra, R. and Maynard, N. and Berrisford, R. and Mercer, S. and Puig, S. and Melhado, R. and Kelty, C. and Underwood, T. and Dawas, K. and Lewis, W. and Al-Bahrani, A. and Bryce, G. and Thomas, M. and Arndt, A.T. and Palazzo, F. and Meguid, R.A. and Fergusson, J. and Beenen, E. and Mosse, C. and Salim, J. and Cheah, S., The influence of anastomotic techniques on postoperative anastomotic complications: Results of the Oesophago-Gastric Anastomosis Audit, Journal of Thoracic and Cardiovascular Surgery, 164, (3), 2022, p674-684.e5 Journal Article, 2022 DOI

Raftery, N.B. and Murphy, C.F. and Donohoe, C.L. and O†Connell, B. and King, S. and Ravi, N. and Reynolds, J.V., The complexity of defining postoperative pneumonia after esophageal cancer surgery: A spectrum of lung injury rather than a simple infective complication?, Annals of Surgery, 276, (5), 2022, pE400-E406 Journal Article, 2022 DOI

Ubels, S. and Verstegen, M.H.P. and Klarenbeek, B.R. and Bouwense, S. and van Berge Henegouwen, M.I. and Daams, F. and van Det, M.J. and Griffiths, E.A. and Haveman, J.W. and Heisterkamp, J. and Nieuwenhuijzen, G. and Polat, F. and Schouten, J. and Siersema, P.D. and Singh, P. and Wijnhoven, B. and Hannink, G. and van Workum, F. and Rosman, C. and Matthée, E. and Slootmans, C.A.M. and Ultee, G. and Gisbertz, S.S. and Eshuis, W.J. and Kalff, M.C. and Feenstra, M.L. and van der Peet, D.L. and Stam, W.T. and Van Etten, B. and Poelmann, F. and Vuurberg, N. and van den Berg, J.W. and Martijnse, I.S. and Matthijsen, R.M. and Luyer, M. and Curvers, W. and Nieuwenhuijzen, T. and Taselaar, A.E. and Kouwenhoven, E.A. and Lubbers, M. and Sosef, M. and Lecot, F. and Geraedts, T.C.M. and van Esser, S. and Dekker, J.W.T. and van den Wildenberg, F. and Kelder, W. and Lubbers, M. and Baas, P.C. and de Haas, J.W.A. and Hartgrink, H.H. and Bahadoer, R.R. and van Sandick, J.W. and Hartemink, K.J. and Veenhof, X. and Stockmann, H. and Gorgec, B. and Weeder, P. and Wiezer, M.J. and Genders, C.M.S. and Belt, E. and Blomberg, B. and van Duijvendijk, P. and Claassen, L. and Reetz, D. and Steenvoorde, P. and Mastboom, W. and Ganseij, H.J.K. and van Dalsen, A.D. and Joldersma, A. and Zwakman, M. and Groenendijk, R.P.R. and Montazeri, M. and Mercer, S. and Knight, B. and van Boxel, G. and McGregor, R.J. and Skipworth, R.J.E. and Frattini, C. and Bradley, A. and Nilsson, M. and Hayami, M. and Huang, B. and Bundred, J. and Evans, R. and Grimminger, P.P. and van Der Sluis, P.C. and Eren, U. and Saunders, J. and Theophilidou, E. and Khanzada, Z. and Elliott, J.A. and Ponten, J.E.H. and King, S. and Reynolds, J.V. and Sgromo, B. and Akbari, K. and Shalaby, S. and Gutschow, C.A. and Schmidt, H. and Vetter, D. and Moorthy, K. and Ibrahim, M.A.H. and Christodoulidis, G. and RÀsÀnen, J.V. and Kauppi, J. and Söderström, H. and Koshy, R. and Manatakis, D.K. and Korkolis, D.P. and Balalis, D. and Rompu, A. and Alkhaffaf, B. and Alasmar, M. and Arebi, M. and Piessen, G. and Nuytens, F. and Degisors, S. and Ahmed, A. and Boddy, A. and Gandhi, S. and Fashina, O. and Van Daele, E. and Pattyn, P. and Robb, W.B. and Arumugasamy, M. and Al Azzawi, M. and Whooley, J. and Colak, E. and Aybar, E. and Sari, A.C. and Uyanik, M.S. and Ciftci, A.B. and Sayyed, R. and Ayub, B. and Murtaza, G. and Saeed, A. and Ramesh, P. and Charalabopoulos, A. and Liakakos, T. and Schizas, D. and Baili, E. and Kapelouzou, A. and Valmasoni, M. and Pierobon, E.S. and Capovilla, G. and Merigliano, S. and Constantinoiu, S. and Birla, R. and Achim, F. and Rosianu, C.G. and Hoara, P. and Castro, R.G. and Salcedo, A.F. and Negoi, I. and Negoita, V.M. and Ciubotaru, C. and Stoica, B. and Hostiuc, S. and Colucci, N. and Mönig, S.P. and Wassmer, C.-H. and Meyer, J. and Takeda, F.R. and Sallum, R.A.A. and Ribeiro, U. and Cecconello, I. and Toledo, E. and Trugeda, M.S. and Fernández, M.J. and Gil, C. and Castanedo, S. and Isik, A. and Kurnaz, E. and Videira, J.F. and Peyroteo, M. and Canotilho, R. and Weindelmayer, J. and Giacopuzzi, S. and De Pasqual, C.A. and Bruna, M. and Mingol, F. and Vaque, J. and Pérez, C. and Phillips, A.W. and Chmelo, J. and Brown, J. and Koshy, R. and Han, L.E. and Gossage, J.A. and Dav, Severity of oEsophageal Anastomotic Leak in patients after oesophagectomy: the SEAL score, British Journal of Surgery, 109, (9), 2022, p864-871 Journal Article, 2022 DOI

Bennett, S. and Murphy, C.F. and Fanning, M. and Reynolds, J.V. and Doyle, S.L. and Donohoe, C.L., The impact of Nutrition and Gastrointestinal Symptoms on Health-related Quality of Life in Survivorship after Oesophageal Cancer Surgery, Clinical Nutrition Open Science, 41, 2022, p44-61 Journal Article, 2022 DOI

Duff, A.-M. and Lambe, G. and Donlon, N.E. and Donohoe, C.L. and Brady, A.-M. and Reynolds, J.V., Interventions targeting postoperative pulmonary complications (PPCs) in patients undergoing esophageal cancer surgery: a systematic review of randomized clinical trials and narrative discussion, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 35, (10), 2022 Journal Article, 2022 DOI

Gillman A, Hayes M; Sheaf G, Walshe M, Reynolds JV, Regan J, Exercise-Based Dysphagia Rehabilitation for Adults with Oesophageal Cancer: a Systematic Review, BMC Cancer, 2022 Journal Article, 2022 DOI

Reynolds JV, Donlon NE, Elliott JA, Moran B, Temperley H, Nugent TS, Davern M, King S, Conroy M, Lysaght J, Ravi N, Ryan C, Finn S, Norris S, Donohoe CL., Incidence and Impact of Non-alcoholic Fatty Liver Disease (NAFLD) in Patients with Adenocarcinoma of the Esophagus Treated with Curative Intent., World Journal of Surgery, 2022 Journal Article, 2022 DOI

Davern M, Donlon NE, O'Connell F, Gaughan C, O'Donovan C, McGrath J, Sheppard AD, Hayes C, King R, Temperley H, MacLean M, Bulter C, Bhardwaj A, Moore J, Donohoe C, Ravi N, Conroy MJ, Reynolds JV, Lysaght J., Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for immunotherapy., Journal of Cancer Research and Clinical Oncology, 2022 Journal Article, 2022 DOI

Michelle Hayes; Anna Gillman; Brona Wright; Sean Dorgan; Ian Brennan; Margaret Walshe; Claire Donohoe; John V Reynolds; Julie Regan, Prevalence, nature and trajectory of dysphagia postoesophageal cancer surgery: a prospective longitudinal study protocol, BMJ Open, 2022 Journal Article, 2022 DOI

Davern M, Donlon NE, Sheppard AS, Majcher KD, Connell FO, Heeran AB, Grant M, Farrell RA, Hayes C, Bracken-Clarke D, Conroy MJ, Foley E, Toole DO, Bhardwaj A, Ravi N, Reynolds JV, Maher SG, Sullivan JO, Lysaght J., FLOT and CROSS chemotherapy regimens alter the frequency of CD27+ and CD69+ T cells in oesophagogastric adenocarcinomas: implications for combination with immunotherapy, Journal of Cancer Research and Clinical Oncology, 2022 Journal Article, 2022 URL

Mylod E, McKenna E, Davern M, Barr MP, Donlon NE, Bibby BA, Bhardwaj A, Reynolds JV, Lysaght J, Maher SG, Conroy MJ., Investigating the susceptibility of treatment-resistant oesophageal tumours to natural killer cell-mediated responses, Clinical and Experimental Medicine, 2022 Journal Article, 2022 DOI TARA - Full Text

Markar, S.R. and Zaninotto, G. and Castoro, C. and Johar, A. and Lagergren, P. and Elliott, J.A. and Gisbertz, S.S. and Mariette, C. and Alfieri, R. and Huddy, J. and Sounderajah, V. and Pinto, E. and Scarpa, M. and Klevebro, F. and Sunde, B. and Murphy, C.F. and Greene, C. and Ravi, N. and Piessen, G. and Brenkman, H. and Ruurda, J.P. and Van Hillegersberg, R. and Lagarde, S. and Wijnhoven, B. and Pera, M. and Roig, J. and Castro, S. and Matthijsen, R. and Findlay, J. and Antonowicz, S. and Maynard, N. and Mccormack, O. and Ariyarathenam, A. and Sanders, G. and Cheong, E. and Jaunoo, S. and Allum, W. and Van Lanschot, J. and Nilsson, M. and Reynolds, J.V. and Henegouwen, M.I.V.B. and Hanna, G.B., Lasting Symptoms After Esophageal Resection (LASER): European Multicenter Cross-sectional Study, Annals of Surgery, 275, (2), 2022, pE392-E400 Journal Article, 2022 DOI

Guo, N. and Minas, G. and Synowsky, S.A. and Dunne, M.R. and Ahmed, H. and McShane, R. and Bhardwaj, A. and Donlon, N.E. and Lorton, C. and O'Sullivan, J. and Reynolds, J.V. and Caie, P.D. and Shirran, S.L. and Lynch, A.G. and Stewart, A.J. and Arya, S., Identification of plasma proteins associated with oesophageal cancer chemotherapeutic treatment outcomes using SWATH-MS, Journal of Proteomics, 266, (104684), 2022 Journal Article, 2022 DOI

Brennan, L., Sadeghi, F., O'Neill, L., Guinan, E., Smyth, L. Sheill, G., Smyth, E., Doyle, S.L., Timon, C., Connolly, D., O'Sullivan, J., Reynolds, J.V., and Hussey, J., Telehealth Delivery of a Multi-Disciplinary Rehabilitation Programme for Upper Gastro-Intestinal Cancer: ReStOre@Home Feasibility Study, Cancers, 2022 Journal Article, 2022 DOI

Temperley, H.C. and Gaule, R. and Murray, C. and Carey, J. and O†Sullivan, N.J. and Davey, M.G. and Fanning, M. and Bolger, J.C. and Ravi, N. and Reynolds, J.V. and Donohoe, C.L., Vitamin B12 supplementation post-gastrectomy: a service closed-loop audit at St. James†s Hospital, Dublin, Irish Journal of Medical Science, 2022 Journal Article, 2022 DOI

Davern M, Fitzgerald MC, Buckley CE, Heeran AB, Donlon NE, McGrath J, O'Connell F, Deshpande MR, Hayes C, MacDonald J, Sheppard AD, Reynolds JV, Maher SG, Lynam-Lennon N, Murphy B, Lysaght J, PD-1 and TIGIT blockade differentially affect tumour cell survival under hypoxia and glucose deprived conditions in oesophageal adenocarcinoma; implications for overcoming resistance to PD-1 blockade in hypoxic tumours, Cancer Letters, 2022 Journal Article, 2022

Nilsson, M. and Olafsdottir, H. and Alexandersson von Döbeln, G. and Villegas, F. and Gagliardi, G. and Hellström, M. and Wang, Q.-L. and Johansson, H. and Gebski, V. and Hedberg, J. and Klevebro, F. and Markar, S. and Smyth, E. and Lagergren, P. and Al-Haidari, G. and Rekstad, L.C. and Aahlin, E.K. and Wallner, B. and Edholm, D. and Johansson, J. and Szabo, E. and Reynolds, J.V. and Pramesh, C.S. and Mummudi, N. and Joshi, A. and Ferri, L. and Wong, R.K.S. and O†Callaghan, C. and Lukovic, J. and Chan, K.K.W. and Leong, T. and Barbour, A. and Smithers, M. and Li, Y. and Kang, X. and Kong, F.-M. and Chao, Y.-K. and Crosby, T. and Bruns, C. and van Laarhoven, H. and van Berge Henegouwen, M. and van Hillegersberg, R. and Rosati, R. and Piessen, G. and de Manzoni, G. and Lordick, F., Neoadjuvant Chemoradiotherapy and Surgery for Esophageal Squamous Cell Carcinoma Versus Definitive Chemoradiotherapy With Salvage Surgery as Needed: The Study Protocol for the Randomized Controlled NEEDS Trial, Frontiers in Oncology, 12, (917961), 2022 Journal Article, 2022 DOI

Elliott, J.A. and Donlon, N.E. and Beddy, P. and Donohoe, C.L. and Doyle, S.L. and King, S. and Ravi, N. and Reynolds, J.V., Visceral obesity with and without metabolic syndrome: incidence and clinical impact in esophageal adenocarcinoma treated with curative intent, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 35, (9), 2022 Journal Article, 2022 DOI

Kroese, T.E. and van Hillegersberg, R. and Schoppmann, S. and Deseyne, P.R.A.J. and Nafteux, P. and Obermannova, R. and Nordsmark, M. and Pfeiffer, P. and Hawkings, M.A. and Smyth, E. and Markar, S. and Hanna, G.B. and Cheong, E. and Chaudry, A. and Elme, A. and Adenis, A. and Piessen, G. and Gani, C. and Bruns, C.J. and Moehler, M. and Liakakos, T. and Reynolds, J. and Morganti, A. and Rosati, R. and Castoro, C. and D'Ugo, D. and Roviello, F. and Bencivenga, M. and de Manzoni, G. and Jeene, P. and van Sandick, J.W. and Muijs, C. and Slingerland, M. and Nieuwenhuijzen, G. and Wijnhoven, B. and Beerepoot, L.V. and Kolodziejczyk, P. and Polkowski, W.P. and Alsina, M. and Pera, M. and Kanonnikoff, T.F. and Nilsson, M. and Guckenberger, M. and Monig, S. and Wagner, D. and Wyrwicz, L. and Berbee, M. and Gockel, I. and Lordick, F. and Griffiths, E.A. and Verheij, M. and van Rossum, P.S.N. and van Laarhoven, H.W.M. and Rosman, C. and RÃŒtten, H. and Gootjes, E.C. and Vonken, F.E.M. and van Dieren, J.M. and Vollebergh, M.A. and van der Sangen, M. and Creemers, G.-J. and Zander, T. and Schlöà er, H. and Cascinu, S. and Mazza, E. and Nicoletti, R. and Damascelli, A. and Slim, N. and Passoni, P. and Cossu, A. and Puccetti, F. and Barbieri, L. and Fanti, L. and Azzolini, F. and Ventoruzzo, F. and Szczepanik, A. and Visa, L. and Reig, A. and Roques, T. and Harrison, M. and CiseÅ', B. and PikuÅ'a, A. and Skórzewska, M. and Vanommeslaeghe, H. and Van Daele, E. and Pattyn, P. and Geboes, K. and Callebout, E. and Ribeiro, S. and van Duijvendijk, P. and Tromp, C. and Sosef, M. and Warmerdam, F. and Heisterkamp, J. and Vera, A. and Jordá, E. and López-Mozos, F. and Fernandez-Moreno, M.C. and Barrios-Carvajal, M. and Huerta, M. and de Steur, W. and Lips, I. and Diez, M. and Castro, S. and O'Neill, R. and Holyoake, D. and Hacker, U. and Denecke, T. and Kuhnt, T. and Hoffmeister, A. and Kluge, R. and Bostel, T. and Grimminger, P. and JedliÄ ka, V. and KŠístek, J. and Pospíšil, P. and Mourregot, A. and Maurin, C. and Starling, N. and Chong, I., Definitions and treatment of oligometastatic oesophagogastric cancer according to multidisciplinary tumour boards in Europe, European Journal of Cancer, 164, 2022, p18-29 Journal Article, 2022 DOI

Raftery, N.B. and Murphy, C.F. and Donohoe, C.L. and O'Connell, B. and King, S. and Ravi, N. and Reynolds, J.V., The Complexity of Defining Postoperative Pneumonia After Esophageal Cancer Surgery: A Spectrum of Lung Injury Rather Than a Simple Infective Complication?, Annals of surgery, 276, (5), 2022, pe400-e406 Journal Article, 2022 DOI

Kamarajah, S.K. and Nepogodiev, D. and Bekele, A. and Cecconello, I. and Evans, R.P.T. and Guner, A. and Gossage, J.A. and Harustiak, T. and Hodson, J. and Isik, A. and Kidane, B. and Leon-Takahashi, A.M. and Mahendran, H.A. and Negoi, I. and Okonta, K.E. and Rosero, G. and Sayyed, R.H. and Singh, P. and Takeda, F.R. and van Hillegersberg, R. and Vohra, R.S. and White, R.E. and Griffiths, E.A. and Alderson, D. and Bundred, J. and Gossage, J. and Jefferies, B. and McKay, S. and Mohamed, I. and Siaw- Acheampong, K. and Vohra, R. and Wanigasooriya, K. and Whitehouse, T. and Gjata, A. and Moreno, J.I. and Guevara, C.R. and Kechagias, A. and Gockel, I. and Kennedy, A. and Da Roit, A. and Bagajevas, A. and Azagra, J.S. and Mejía-Fernández, L. and Wijnhoven, B.P.L. and El Kafsi, J. and Sousa, M. and Sampaio, A.S. and Blanco, R. and Wallner, B. and Schneider, P.M. and Hsu, P.K. and Gananadha, S. and Wills, V. and Devadas, M. and Duong, C. and Talbot, M. and Hii, M.W. and Jacobs, R. and Andreollo, N.A. and Johnston, B. and Darling, G. and Isaza-Restrepo, A. and Arias- Amézquita, F. and Raptis, D. and Gaedcke, J. and Reim, D. and Izbicki, J. and Egberts, J.H. and Dikinis, S. and Kjaer, D.W. and Larsen, M.H. and Achiam, M.P. and Saarnio, J. and Theodorou, D. and Liakakos, T. and Korkolis, D.P. and Robb, W.B. and Collins, C. and Murphy, T. and Reynolds, J. and Tonini, V. and Migliore, M. and Bonavina, L. and Valmasoni, M. and Bardini, R. and Weindelmayer, J. and Terashima, M. and Alghunaim, E. and Elhadi, M. and Medina-Franco, H. and Lau, P.C. and Heisterkamp, J. and Rosman, C. and Beban, G. and Babor, R. and Gordon, A. and Rossaak, J.I. and Pal, K.M.I. and Qureshi, A.U. and Naqi, S.A. and Syed, A.A. and Barbosa, J. and Vicente, C.S. and Leite, J. and Freire, J. and Casaca, R. and Costa, R.C.T. and Scurtu, R.R. and Mogoanta, S.S. and Bolca, C. and Constantinoiu, S. and Sekhniaidze, D. and BjeloviÄ , M. and So, J.B.Y. and GaÄ evski, G. and Loureiro, C. and Pera, M. and Bianchi, A. and Moreno, G.M. and Martín Fernández, J. and Trugeda Carrera, M.S. and Vallve-Bernal, M. and Cítores Pascual, M.A. and Elmahi, S. and Halldestam, I. and Hedberg, J. and Mönig, S. and Gutknecht, S. and Tez, M. and Tirnaksiz, M.B. and Colak, E. and Sevinç, B. and Hindmarsh, A. and Khan, I. and Khoo, D. and Byrom, R. and Gokhale, J. and Wilkerson, P. and Jain, P. and Chan, D. and Robertson, K. and Iftikhar, S. and Skipworth, R. and Forshaw, M. and Higgs, S. and Nijjar, R. and Viswanath, Y.K.S. and Turner, P. and Dexter, S. and Boddy, A. and Allum, W.H. and Oglesby, S. and Cheong, E. and Beardsmore, D. and Maynard, N. and Berrisford, R. and Mercer, S. and Puig, S. and Melhado, R. and Kelty, C. and Underwood, T. and Dawas, K. and Lewis, W. and Al-Bahrani, A. and Bryce, G. and Thomas, M. and Arndt, A.T. and Palazzo, F. and Meguid, R.A. and Fergusson, J. and Beenen, E. and Mosse, C. and Salim, J. and Cheah, S. and Wright, T. and Cerdeira, M.P. and McQuillan, P. and Richardson, M. and Liem, H. and Spillane, J. and Yacob, M. and Albadawi, F. and Thorpe, T. and Dingle, A. and Cabalag, C. and Loi, K. and Fisher, O.M. and Ward, S. and Read, M. and Johnson, M. and Bassari, R. and Bui, H. and Sallum, R.A.A. and da Rocha, J.R.M. and Lopes, L.R. and Tercioti, V. and Coelho, J.D. and Ferrer, J.A.P., Mortality from esophagectomy for esophageal cancer across low, middle, and high-income countries: An international cohort study, European Journal of Surgical Oncology, 2021 Journal Article, 2021 DOI TARA - Full Text

Ashanty M.Melo, Eimear Mylod, Vivienne Fitzgerald, Noel E.Donlon, Dearbhla M. Murphy, Emma K.Foley, Anshul Bhardwaj, John V.Reynolds, Derek G.Doherty, Joanne Lysaght, Margaret R. Dunne, Melissa J. Conroy, Tissue distribution of γδ T cell subsets in oesophageal adenocarcinoma, Clinical Immunology, 229, 2021 Journal Article, 2021 DOI TARA - Full Text

Lorton, Cliona M., Higgins, Larissa, O'Donoghue, Niamh, Donohoe, Claire, O'Connell, Jim, Mockler, David, Reynolds, John V., Walsh, Declan, Lysaght, Joanne, C-Reactive Protein and C-Reactive Protein-Based Scores to Predict Survival in Esophageal and Junctional Adenocarcinoma: Systematic Review and Meta-Analysis, Annals of Surgical Oncology, 2021 Journal Article, 2021 DOI

Murphy, C.F. and Elliott, J.A. and Docherty, N.G. and Mohamed, A.A. and Vincent, R.P. and Ravi, N. and Reynolds, J.V. and Le Roux, C.W., Exaggerated postprandial GLP-1 secretion following esophagectomy is not associated with gastric emptying and intestinal transit, Diseases of the Esophagus, 34, (7), 2021 Journal Article, 2021 DOI

Bennett, A.E., O'Neill, L., Connolly, D., Guinan, E., Boland, L., Doyle, S., O'Sullivan, J., Reynolds, J.V., Hussey, J., Perspectives of Esophageal Cancer Survivors on Diagnosis, Treatment, and Recovery., Cancers, 13, (1), 2021, p1-12 Journal Article, 2021 URL DOI

Heeran AB, McCready J, Dunne MR, Donlon NE, Nugent TS, Bhardwaj A, Mitchelson KAJ, Buckley AM, Ravi N, Roche HM, Reynolds JV, Lynam-Lennon N, O'Sullivan J., Opposing Immune-Metabolic Signature in Visceral Versus Subcutaneous Adipose Tissue in Patients with Adenocarcinoma of the Oesophagus and the Oesophagogastric Junction., Metabolites, 11, (11), 2021 Journal Article, 2021 DOI

Lugaresi, M. and Nafteux, P. and Nilsson, M. and Reynolds, J.V. and Rosati, R. and Schoppmann, S.F. and Targarona, E.M. and Mattioli, S., Exploring the concept of centralization of surgery for benign esophageal diseases: A Delphi based consensus from the European Society for Diseases of the Esophagus, Diseases of the Esophagus, 34, (9), 2021 Journal Article, 2021 DOI

Kennedy, S.A., Annett, S.L., Dunne, M.R., Boland, F., O'Neill, L.M., Guinan, E.M., Doyle, S.L., Foley, E.K., Elliott, J.A., Murphy, C.F., Bennett, A.E., Carey, M., Hillary, D., Robson, T., Reynolds, J.V., Hussey, J., O'Sullivan, J.N., Effect of the Rehabilitation Program, ReStOre, on Serum Biomarkers in a Randomized Control Trial of Esophagogastric Cancer Survivors, Frontiers in Oncology, 11, (669078), 2021, p1-11 Journal Article, 2021 DOI

Donlon, N.E. and Power, R. and Hayes, C. and Davern, M. and Reynolds, J.V. and Lysaght, J., Radiation and immunotherapy in upper gastrointestinal cancers: The current state of play, International Journal of Molecular Sciences, 22, (3), 2021, p1-15 Journal Article, 2021 DOI TARA - Full Text

Murphy, C.F. and Dunne, T. and Elliott, J.A. and Kamarajah, S.K. and Leighton, J. and Evans, R.P.T. and Bundred, J. and King, S. and Ravi, N. and Donohoe, C.L. and Griffin, S.M. and Griffiths, E.A. and Phillips, A.W. and Reynolds, J.V., Response to the Comment on "acute Kidney Injury after Esophageal Cancer Surgery: Incidence, Risk Factors, and Impact on Oncologic Outcomes", Annals of Surgery, 274, (6), 2021, pE850-E851 Journal Article, 2021 DOI

Raftery, N.B. and Murphy, C.F. and Donohoe, C.L. and O'Connell, B. and King, S. and Ravi, N. and Reynolds, J.V., Response to Comment on "the Complexity of Defining Postoperative Pneumonia following Esophageal Cancer Surgery: A Spectrum of Lung Injury Rather Than a Simple Infective Complication? (ANNSURG-D21-00007)", Annals of Surgery, 274, (6), 2021, pE896-E897 Journal Article, 2021 DOI

Elliott, J.A. and Reynolds, J.V., Visceral Obesity, Metabolic Syndrome, and Esophageal Adenocarcinoma, Frontiers in Oncology, 11, (627270), 2021 Journal Article, 2021 DOI

Donlon, N.E. and Ravi, N. and King, S. and Cunninhgam, M. and Cuffe, S. and Lowery, M. and Wall, C. and Hughes, N. and Muldoon, C. and Ryan, C. and Moore, J. and O†Farrell, C. and Gorry, C. and Duff, A.-M. and Enright, C. and Nugent, T.S. and Elliot, J.A. and Donohoe, C.L. and Reynolds, J.V., Modern oncological and operative outcomes in oesophageal cancer: the St. James†s hospital experience, Irish Journal of Medical Science, 190, (1), 2021, p297-305 Journal Article, 2021 DOI

Emily Smyth, Louise O'Connor, David Mockler, John V. Reynolds, Juliette Hussey, Emer Guinan, Preoperative high intensity interval training for oncological resections: A systematic review and meta-analysis, Surgical Oncology, 38, 2021, p101620 Journal Article, 2021

Alhusaini A, Cannon A, Maher SG, Reynolds JV, Lynam-Lennon N., Therapeutic Potential of PARP Inhibitors in the Treatment of Gastrointestinal Cancers., Biomedicines, 9, (8), 2021 Journal Article, 2021 DOI

Donlon, N.E. and Kammili, A. and Roopnarinesingh, R. and Davern, M. and Power, R. and King, S. and Chmelo, J. and Phillips, A.W. and Donohoe, C.L. and Ravi, N. and Lowery, M. and Mueller, C.L. and Cools-Lartigue, J. and Ferri, L.E. and Reynolds, J.V., FLOT-regimen Chemotherapy and Transthoracic en bloc Resection for Esophageal and Junctional Adenocarcinoma, Annals of Surgery, 274, (5), 2021, p814-820 Journal Article, 2021 DOI

Bolger, J.C. and Reynolds, J.V., Organ preservation in the multimodality approach to locally advanced oesophageal cancer: festina lente, The British journal of surgery, 108, (10), 2021, p1142-1144 Journal Article, 2021 DOI

Donlon, N.E. and Davern, M. and Sheppard, A. and Power, R. and O†connell, F. and Heeran, A.B. and King, R. and Hayes, C. and Bhardwaj, A. and Phelan, J.J. and Dunne, M.R. and Ravi, N. and Donohoe, C.L. and O†sullivan, J. and Reynolds, J.V. and Lysaght, J., The prognostic value of the lymph node in oesophageal adenocarcinoma; incorporating clinicopathological and immunological profiling, Cancers, 13, (16), 2021 Journal Article, 2021 DOI

Pucher, P.H. and Wijnhoven, B.P.L. and Underwood, T.J. and Reynolds, J.V. and Davies, A.R., Thinking through the multimodal treatment of localized oesophageal cancer: the point of view of the surgeon, Current opinion in oncology, 33, (4), 2021, p353-361 Journal Article, 2021 DOI

Rice, D. and Fearon, N. and Reynolds, J.V. and Ravi, N., Descending necrotising mediastinitis: How a sore throat can result in purulent peritonitis, BMJ Case Reports, 14, (5), 2021 Journal Article, 2021 DOI

Davern M, Donlon NE, Power R, Hayes C, King R, Dunne MR, Reynolds JV., The tumour immune microenvironment in oesophageal cancer., British journal of cancer, 2021 Journal Article, 2021 DOI

D'Journo, X.B. and Boulate, D. and Fourdrain, A. and Loundou, A. and Van Berge Henegouwen, M.I. and Gisbertz, S.S. and O'Neill, J.R. and Hoelscher, A. and Piessen, G. and Van Lanschot, J. and Wijnhoven, B. and Jobe, B. and Davies, A. and Schneider, P.M. and Pera, M. and Nilsson, M. and Nafteux, P. and Kitagawa, Y. and Morse, C.R. and Hofstetter, W. and Molena, D. and So, J.B.-Y. and Immanuel, A. and Parsons, S.L. and Larsen, M.H. and Dolan, J.P. and Wood, S.G. and Maynard, N. and Smithers, M. and Puig, S. and Law, S. and Wong, I. and Kennedy, A. and Kangning, W. and Reynolds, J.V. and Pramesh, C.S. and Ferguson, M. and Darling, G. and Schröder, W. and Bludau, M. and Underwood, T. and Van Hillegersberg, R. and Chang, A. and Cecconello, I. and Ribeiro, U. and De Manzoni, G. and Rosati, R. and Kuppusamy, M. and Thomas, P.A. and Low, D.E., Risk Prediction Model of 90-Day Mortality after Esophagectomy for Cancer, JAMA Surgery, 156, (9), 2021, p836-845 Journal Article, 2021 DOI

Markar, S.R. and Sounderajah, V. and Johar, A. and Zaninotto, G. and Castoro, C. and Lagergren, P. and Elliott, J.A. and Gisbertz, S.S. and Mariette, C. and Alfieri, R. and Huddy, J. and Pinto, E. and Scarpa, M. and Klevebro, F. and Sunde, B. and Murphy, C.F. and Greene, C. and Ravi, N. and Piessen, G. and Brenkman, H. and Ruurda, J. and van Hillegersberg, R. and Lagarde, S.M. and Wijnhoven, B.P. and Pera, M. and Roigg, J. and Castro, S. and Matthijsen, R. and Findlay, J. and Antonowicz, S. and Maynard, N. and McCormack, O. and Ariyarathenam, A. and Sanders, G. and Cheong, E. and Jaunoo, S. and Allum, W. and van Lanschot, J. and Nilsson, M. and Reynolds, J.V. and van Berge Henegouwen, M.I. and Hanna, G.B., Patient-reported outcomes after oesophagectomy in the multicentre LASER study, The British journal of surgery, 108, (9), 2021, p1090-1096 Journal Article, 2021 DOI

Donlon, N.E. and Power, R. and Hayes, C. and Reynolds, J.V. and Lysaght, J., Radiotherapy, immunotherapy, and the tumour microenvironment: Turning an immunosuppressive milieu into a therapeutic opportunity, Cancer Letters, 502, 2021, p84-96 Journal Article, 2021 DOI TARA - Full Text

Lugaresi, M. and Nafteux, P. and Nilsson, M. and Reynolds, J.V. and Rosati, R. and Schoppmann, S.F. and Targarona, E.M. and Mattioli, S., Erratum: Exploring the concept of centralization of surgery for benign esophageal diseases: A Delphi based consensus from the European Society for Diseases of the Esophagus (Diseases of the Esophagus (doab013) DOI: 10.1093/dote/doab013), Diseases of the Esophagus, 34, (8), 2021 Journal Article, 2021 DOI

Labgaa, I. and Mantziari, S. and Genety, M. and Elliott, J.A. and Kamiya, S. and Kalff, M.C. and Winiker, M. and Pasquier, J. and Allemann, P. and Messier, M. and van Berge Henegouwen, M.I. and Nilsson, M. and Reynolds, J.V. and Piessen, G. and HÌbner, M. and Demartines, N. and SchÀfer, M., Early postoperative decrease of albumin is an independent predictor of major complications after oncological esophagectomy: A multicenter study, Journal of Surgical Oncology, 123, (2), 2021, p462-469 Journal Article, 2021 DOI

O'Connor, L., Smyth, E., Bennett, A.E.. Smith, V., O'Neill, L., Reynolds, J.V.,. Hussey, J., Guinan, E.M., Identifying outcomes reported in exercise interventions in oesophagogastric cancer survivors: a systematic review, BMC Cancer, 21, (586), 2021, p1-9 Journal Article, 2021 DOI URL

O'Brien RM, Cannon A, Reynolds JV, Lysaght J, Lynam-Lennon N., Complement in Tumourigenesis and the Response to Cancer Therapy., Cancers, 13, (6), 2021 Journal Article, 2021 DOI

Roopnarinesingh, R.C. and Donlon, N.E. and Reynolds, J.V., Alkaptonuria: clinical manifestations and an updated approach to treatment of a rare disease, BMJ Case Reports, 14, (12), 2021 Journal Article, 2021 DOI

Sullivan, E.S. and Rice, N. and Kingston, E. and Kelly, A. and Reynolds, J.V. and Feighan, J. and Power, D.G. and Ryan, A.M., A national survey of oncology survivors examining nutrition attitudes, problems and behaviours, and access to dietetic care throughout the cancer journey, Clinical Nutrition ESPEN, 41, 2021, p331-339 Journal Article, 2021 DOI

Morgan, E. and Soerjomataram, I. and Gavin, A.T. and Rutherford, M.J. and Gatenby, P. and Bardot, A. and Ferlay, J. and Bucher, O. and De, P. and Engholm, G. and Jackson, C. and Kozie, S. and Little, A. and MÞller, B. and Shack, L. and Tervonen, H. and Thursfield, V. and Vernon, S. and Walsh, P.M. and Woods, R.R. and Finley, C. and Merrett, N. and O'Connell, D.L. and Reynolds, J.V. and Bray, F. and Arnold, M., International trends in oesophageal cancer survival by histological subtype between 1995 and 2014, Gut, 70, (2), 2021, p234-242 Journal Article, 2021 DOI

Davern M, Donlon NE, Sheppard A, Connell FO, Hayes C, Bhardwaj A, Foley E, Toole DO, Lynam-Lennon N, Ravi N, Reynolds JV, Maher SG, Lysaght J., Chemotherapy regimens induce inhibitory immune checkpoint protein expression on stem-like and senescent-like oesophageal adenocarcinoma cells., Translational oncology, 14, (6), 2021, p101062 Journal Article, 2021 DOI

Chin, J.L. and O'Connell, J. and Muldoon, C. and Swan, N. and Reynolds, J.V. and Ravi, N. and Geoghegan, J. and Conlon, K.C. and O'Shea, D. and O'Toole, D., Selective Resection of Type 1 Gastric Neuroendocrine Neoplasms and the Risk of Progression in an Endoscopic Surveillance Programme, Digestive Surgery, 38, (1), 2021, p38-45 Journal Article, 2021 DOI

ALKHAFFAF B., BLAZEBY JM, ET AL AND ON BEHALF OF THE GASTROS INTERNATIONAL WORKING GROUP, Methods for conducting international Delphi surveys to optimise global participation in core outcome set development: a case study in gastric cancer informed by a comprehensive literature review, Trials, 2021, phttps://doi.org/10.1186/s13063 Journal Article, 2021 DOI

Power, R. and Smyth, P. and Donlon, N.E. and Nugent, T. and Donohoe, C.L. and Reynolds, J.V., Management of chyle leaks following esophageal resection: a systematic review, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 34, (11), 2021 Journal Article, 2021 DOI

Ubels, S. and Verstegen, M.H.P. and Rosman, C. and Reynolds, J.V., Anastomotic leakage after esophagectomy for esophageal cancer: Risk factors and operative treatment, Annals of Esophagus, 3, (8), 2021 Journal Article, 2021 DOI

Conroy MJ, Kennedy SA, Doyle SL, Hayes B, Kavanagh M, van der Stok EP, O'Sullivan K, Cathcart MC, Reynolds JV, Lysaght J., A study of the immune infiltrate and patient outcomes in esophageal cancer., Carcinogenesis, 42, (3), 2021, p395-404 Journal Article, 2021 DOI

Raftery, N.B. and Murphy, C.F. and Donlon, N.E. and Heneghan, H. and Donohoe, C.L. and King, S. and O'Connell, B. and Ravi, N. and Reynolds, J.V., Prospective study of surgical site infections post-open esophageal cancer surgery, and the impact of care bundles, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 34, (12), 2021 Journal Article, 2021 DOI

Mylod, E. and Melo, A.M. and Donlon, N.E. and Davern, M. and Bhardwaj, A. and Reynolds, J.V. and Lysaght, J. and Conroy, M.J., Fractalkine elicits chemotactic, phenotypic, and functional effects on cx3cr1+cd272 nk cells in obesity-associated cancer, Journal of Immunology, 207, (4), 2021, p1200-1210 Journal Article, 2021 DOI

Stratford, N.R.S. and Murphy, C.F. and Elliott, J.A. and Reynolds, J.V. and le Roux, C.W., Pharmacologic gut hormone modulation and eating behavior after esophagogastric cancer surgery: a narrative review, Annals of Esophagus, 4, (42), 2021 Journal Article, 2021 DOI

Butt, W.T. and Reynolds, J.V., Isolated oesophageal adenocarcinoma metastasis at percutaneous endoscopic gastrostomy (PEG) site, BMJ case reports, 13, (6), 2020 Journal Article, 2020 DOI

Morrissey ME, Byrne R, Nulty C, McCabe NH, Lynam-Lennon N, Butler CT, Kennedy S, O'Toole D, Larkin J, McCormick P, Mehigan B, Cathcart MC, Lysaght J, Reynolds JV, Ryan EJ, Dunne MR, O'Sullivan J., The tumour microenvironment of the upper and lower gastrointestinal tract differentially influences dendritic cell maturation., BMC Cancer, 20, (1), 2020, p566 Journal Article, 2020 TARA - Full Text DOI

Baiocchi, G.L. and Giacopuzzi, S. and Reim, D. and Piessen, G. and Da Costa, P.M. and Reynolds, J.V. and Meyer, H.-J. and Morgagni, P. and Gockel, I. and Santos, L.L. and Jensen, L.S. and Murphy, T. and D'Ugo, D. and Rosati, R. and Romario, U.F. and Degiuli, M. and Kielan, W. and Monig, S. and KoÅ'odziejczyk, P. and Polkowski, W. and Pera, M. and Schneider, P.M. and Wijnhoven, B. and De Steur, W.O. and Gisbertz, S.S. and Hartgrink, H. and Van Sandick, J.W. and Botticini, M. and Holscher, A.H. and Allum, W. and De Manzoni, G., Incidence and grading of complications after gastrectomy for cancer using the GASTRODATA registry a european retrospective observational study, Annals of Surgery, 272, (5), 2020, p807-813 Journal Article, 2020 DOI

Sheill G., Reynolds S., O'Neill L., Mockler D., Reynolds JV., Hussey J., Guinan E.,, Cardiopulmonary Exercise Testing in Oesophagogastric Surgery: a Systematic Review, Cardiopulmonary Exercise Testing in Oesophagogastric Surgery: a Systematic Review, 2020, p12 Journal Article, 2020 DOI

Donlon, N.E. and Elliott, J.A. and Donohoe, C.L. and Murphy, C.F. and Nugent, T. and Moran, B. and King, S. and Ravi, N. and Reynolds, J.V., Adverse Biology in Adenocarcinoma of the Esophagus and Esophagogastric Junction Impacts Survival and Response to Neoadjuvant Therapy Independent of Anatomic Subtype, Annals of surgery, 272, (5), 2020, p814-819 Journal Article, 2020 DOI

Power R, Lowery MA, Reynolds JV, Dunne MR., The Cancer-Immune Set Point in Oesophageal Cancer., Frontiers in oncology, 10, 2020, p891 Journal Article, 2020 DOI

Sheill G., Guinan E., O'Neill L., Normand C., Doyle SL., Moore S., Newell J., McDermott G., Ryan R., Reynolds JV., Hussey J., Preoperative exercise to improve fitness in patients undergoing complex surgery for cancer of the lung or oesophagus (PREHIIT): protocol for a randomized controlled trial, BMC Cancer, 2020 Journal Article, 2020 DOI

Butterworth, J.W. and Boshier, P.R. and Mavroveli, S. and Van Lanschot, J.B. and Sasako, M. and Reynolds, J.V. and Hanna, G.B., Challenges to quality assurance of surgical interventions in clinical oncology trials: A systematic review, European Journal of Surgical Oncology, 2020 Journal Article, 2020 DOI

Melo A.M., Conroy M.J., Foley E.K., Dockry E., Breen E.P., Reynolds J.V., Lysaght J., Doherty D.G., CD1d expression and invariant natural killer T-cell numbers are reduced in patients with upper gastrointestinal cancers and are further impaired by commonly used chemotherapies, Cancer Immunology, Immunotherapy, 69, (6), 2020, p969 - 982, p969-982 Journal Article, 2020 DOI TARA - Full Text

O'Neill L., Reynolds S., Sheill G., Guinan E., Mockler D., Geoghegan J., Conlon K., Reynolds, J.V., Hussey J., Physical function in patients with resectable cancer of the pancreas and liver-a systematic review, Journal of Cancer Survivorship, 2020 Journal Article, 2020 DOI

Donlon, N.E. and Nugent, T.S. and Power, R. and Butt, W. and Kamaludin, A. and Dolan, S. and Guiney, M. and Mc Eniff, N. and Ravi, N. and Reynolds, J.V., Embolization or disruption of thoracic duct and cisterna chyli leaks post oesophageal cancer surgery should be first line management for ECCG-defined type III chyle fistulae, Irish Journal of Medical Science, 2020 Journal Article, 2020 DOI

O'Neill L., Guinan E., Doyle S., O'Connor L., Sheill G., Smyth E., Fairman C., Segurado R., Connolly D., O'Sullivan J., Reynolds JV., Hussey J, ReStOre@Home: Feasibility study of a virtually delivered 12-week multidisciplinary rehabilitation programme for survivors of upper gastrointestinal (UGI) cancer - study protocol, HRB Open Research, 2020 Journal Article, 2020 DOI

G. Barber, A. Anand, K. Oficjalska, J.J. Phelan, A. B. Heeran, E. Flis, N. E. Clarke, J. A. Watson, J. Strangmann, B. Flood, H. O'Neill, D. O'Toole, F. MacCarthy, N. Ravi, J. V. Reynolds, E.W. Kay, M. Quante, J. O'Sullivan, E.M. Creagh., Characterizing caspase-1 involvement during esophageal disease progression. , Cancer Immunology Immunotherapy, 69, (12), 2020, p2635 - 2649 Journal Article, 2020 DOI TARA - Full Text

Noel E. Donlon and Andrew Sheppard and Maria Davern and Fiona O'Connell and James J. Phelan and Robert Power and Timothy Nugent and Kate Dinneen and John Aird and John Greene and Paul Nevins Selvadurai and Anshul Bhardwaj and Emma K. Foley and Narayanasamy Ravi and Claire L. Donohoe and John V. Reynolds and Joanne Lysaght and Jacintha O'Sullivan and Margaret R. Dunne, Linking Circulating Serum Proteins with Clinical Outcomes in Esophageal Adenocarcinoma"An Emerging Role for Chemokines, Cancers, 12, (11), 2020, p3356 Journal Article, 2020 TARA - Full Text

Boland, P.A. and Donlon, N.E. and Kelly, M.E. and Nugent, T. and Free, R. and Waters, P. and Neary, P. and Rausa, E. and Proud, D. and Donohoe, C.L. and Barry, K.M. and Reynolds, J.V., Current opinions and practices for the management of acute appendicitis: an international survey, Irish Journal of Medical Science, 2020 Journal Article, 2020 DOI

O'NEILL L., GUINAN E., DOYLE S., CONNOLLY D., O'SULLIVAN J., BENNETT A., SHEILL G., SEGURADO R., KNAPP P., FAIRMAN C., NORMAND C., GEOGHEGAN J., CONLON K., REYNOLDS JV., HUSSEY J., Rehabilitation strategies following oesophagogastric and hepatopancreaticobiliary cancer (ReStOre II): a protocol for a randomised controlled trial, BMC Cancer, 20, 2020, p1 - 20 Journal Article, 2020 DOI

C.O'Rourke, I. Welaratneb, S.Cournanec, L.C. McLoughlin, J.V. Reynolds, C. Johnstone, N. Sheehy, Diagnostic accuracy of SUVmax in predicting malignancy of supraclavicular lymph nodes from primary oesophageal cancer., European Radiology, 125, 2020 Journal Article, 2020

Buckley AM, Dunne MR, Morrissey ME, Kennedy SA, Nolan A, Davern M, Foley EK, Clarke N, Lysaght J, Ravi N, O'Toole D, MacCarthy F, Reynolds JV, Kennedy BN, O'Sullivan J., Real-time metabolic profiling of oesophageal tumours reveals an altered metabolic phenotype to different oxygen tensions and to treatment with Pyrazinib., Scientific reports, 10, (1), 2020, p12105 Journal Article, 2020 TARA - Full Text DOI

O†Byrne, L.M. and Witherspoon, J. and Verhage, R.J.J. and O†Brien, M. and Muldoon, C. and Ryan, C. and Buckley, M. and Murphy, T. and Reynolds, R. and Patchett, S. and Kay, E. and Azam, H. and Robb, W. and Arumugasamy, M. and Mathuna, P.M. and Leyden, J. and Gargan, S. and Doherty, G. and Sheahan, K. and Collins, C. and Nath, A. and O†Sullivan, J. and Donohoe, C.L. and Ravi, N. and O†Toole, D. and Reynolds, J.V., Barrett†s Registry Collaboration of academic centers in Ireland reveals high progression rate of low-grade dysplasia and low risk from nondysplastic Barrett†s esophagus: report of the RIBBON network, Diseases of the Esophagus, 33, (10), 2020 Journal Article, 2020 DOI

Barbieri, L. and Urquijo, E.T. and Parise, P. and Nilsson, M. and Reynolds, J.V. and Rosati, R., Esophageal oncologic surgery in SARS-CoV-2 (COVID-19) emergency, Diseases of the Esophagus, 33, (5), 2020, p1-5 Journal Article, 2020 DOI

Khan, N. and Donohoe, C.L. and Phillips, A.W. and Griffin, S.M. and Reynolds, J.V., Signet ring gastric and esophageal adenocarcinomas: characteristics and prognostic implications, Diseases of the Esophagus, 33, (11), 2020, p1-7 Journal Article, 2020 DOI

Butler, J. and Finley, C. and Norell, C.H. and Harrison, S. and Bryant, H. and Achiam, M.P. and Altman, A.D. and Baxter, N. and Bentley, J. and Cohen, P.A. and Chaudry, M.A. and Dixon, E. and Farrell, R. and Fegan, S. and Hashmi, S. and Hogdall, C. and Jenkins, J.T. and Kwon, J. and Mala, T. and McNally, O. and Merrett, N. and Nelson, G. and Nordin, A. and Park, J. and Porter, G. and Reynolds, J. and Schieman, C. and Schnack, T. and Spigelman, A. and Svendsen, L.B. and Sykes, P. and Thomas, R., New approaches to cancer care in a COVID-19 world, The Lancet Oncology, 21, (7), 2020, pe339-e340 Journal Article, 2020 DOI

Martin, D. and Mantziari, S. and Demartines, N. and HÌbner, M. and Bismuth, H. and Sarr, M.G. and Strasberg, S.M. and Wexner, S.D. and Adham, M. and Altomare, D.F. and Andersson, R. and Bechstein, W. and Biondo, S. and Bockhorn, M. and Bonavina, L. and Rituerto, D.C. and Clavien, P.-A. and De Manzini, N. and Decker, G. and Dejong, C.H. and Dervenis, C. and Farges, O. and Figueras, J. and Fingerhut, A.L. and Friess, H. and Glehen, O. and Gnant, M. and Gutschow, C. and Hahnloser, D. and Hamberger, B. and Hamming, J.F. and Hölscher, A.H. and Izbicki, J.R. and Jonas, S. and Karamarkovic, A. and Kehlet, H. and LeppÀniemi, A.K. and Lerut, J. and Line, P.-D. and Lodge, J.P.A. and Meakins, J.L. and Montorsi, M. and Nafteux, P. and Naredi, P. and Oláh, A. and Panis, Y. and Pardo, F. and Parks, R.W. and Pedrazzoli, S. and Pessaux, P. and Marques, H.P. and Poggioli, G. and Popescu, I. and Puolakkainen, P.A. and Ramia Angel, J.M. and Rasanen, J. and Reynolds, J.V. and Rosati, R. and Saeger, H.-D. and Schneeberger, S. and Schneider, P.M. and SÞreide, K. and Stippel, D. and Toso, C. and Tuech, J.-J. and Tukiainen, E.J. and Van Hillegersberg, R. and Wijnhoven, B. and Winter, D.C. and Zaninotto, G., Defining Major Surgery: A Delphi Consensus Among European Surgical Association (ESA) Members, World Journal of Surgery, 44, (7), 2020, p2211-2219 Journal Article, 2020 DOI

Fearon, N.M. and Mohan, H.M. and Fanning, M. and Ravi, N. and Reynolds, J.V., Colonic interposition, a contemporary experience: technical aspects and outcomes, Updates in Surgery, 2020 Journal Article, 2020 DOI

Melo, Ashanty M., O'Brien, Aisling M., Phelan, James J., Kennedy, Susan A., Wood, Nicole A. W., Veerapen, Natacha, Besra, Gurdyal S., Clarke, Niamh E., Foley, Emma K., Ravi, Akshaya, MacCarthy, Finbar, O'Toole, Dermot, Ravi, Narayamasami, Reynolds, John V., Conroy, Melissa J., Hogan, Andrew E., O'Sullivan, Jacintha, Dunne, Margaret R., Mucosal-Associated Invariant T Cells Display Diminished Effector Capacity in Oesophageal Adenocarcinoma, Frontiers in Immunology, 10, 2019 Journal Article, 2019 DOI TARA - Full Text

Bibby BA, Miranda CS, Reynolds JV, Cawthorne CJ, Maher SG, Silencing microRNA-330-5p increases MMP1 expression and promotes an invasive phenotype in oesophageal adenocarcinoma, BMC Cancer, 19, 2019, p784- Journal Article, 2019

El-Mashed, S. and O'Donovan, T.R. and Kay, E.W. and Abdallah, A.R. and Cathcart, M.-C. and O'Sullivan, J. and O'Grady, A. and Reynolds, J. and O'Reilly, S. and O'Sullivan, G.C. and McKenna, S.L., Correction to: LC3B globular structures correlate with survival in esophageal adenocarcinoma (BMC Cancer (2015) 15:582 DOI: 10.1186/s12885-015-1574-5), BMC Cancer, 19, (1), 2019 Journal Article, 2019 DOI

Elliott, J.A. and Docherty, N.G. and Haag, J. and Eckhardt, H.-G. and Ravi, N. and Reynolds, J.V. and Le Roux, C.W., Attenuation of satiety gut hormones increases appetitive behavior after curative esophagectomy for esophageal cancer, American Journal of Clinical Nutrition, 109, (2), 2019, p335-344 Journal Article, 2019 DOI

O†Neill, H. and Malik, V. and Johnston, C. and Reynolds, J.V. and O†sullivan, J., Can the efficacy of [ 18 f]fdg-pet/ct in clinical oncology be enhanced by screening biomolecular profiles?, Pharmaceuticals, 12, (1), 2019 Journal Article, 2019 DOI

Bundred, J.R. and Kamarajah, S.K. and Siaw-Acheampong, K. and Nepogodiev, D. and Jefferies, B. and Singh, P. and Evans, R. and Griffiths, E.A. and Alderson, D. and Gossage, J. and McKay, S. and Mohamed, I. and van Hillegersberg, R. and Vohra, R. and Wanigsooriya, K. and Whitehouse, T. and Bagajevas, A. and Bekele, A. and Blanco-Colino, R. and Da Roit, A. and El Kafsi-Mawley, J. and Gjata, A. and Gockel, I. and Castro, R.G. and Harustiak, T. and Hsu, P.-K. and Isik, A. and Kechagias, A. and Kennedy, A. and Kidane, B. and Mahendran, H.A. and Mejia, L. and Moreno, J.I. and Negoi, I. and Santiago, A.J. and Sayyed, R. and Schneider, P. and Soares, A.S. and Sousa, M. and Takeda, F.R. and Vanstraten, S. and Wallner, B. and Wijnhoven, B. and Achiam, M. and Agustin, T. and Akbar, A. and Al-Bahrani, A. and Al-Khyatt, W. and Albertsmeier, M. and Alghunaim, E. and Alkhaffaf, B. and Allum, W. and Am, F. and Andreollo, N. and Arndt, A. and Babor, R. and Barbosa, J. and Bardini, R. and Beardsmore, D. and Beban, G. and Bernardes, A. and Berrisford, R. and Bianchi, A. and Bjelovic, M. and Boddy, A. and Bolca, C. and Bonavina, L. and Bryce, G. and Byrom, R. and Casaca, R. and Chan, D. and Charalabopoulos, A. and Cheong, E. and Ciotola, F. and Colak, E. and Collins, C. and Constantinoiu, S. and Costa, R. and Dahlke, M. and Darling, G. and Dawas, K. and de Manzoni, G. and Denewer, A. and Devadas, M. and Dexter, S. and Dikinis, S. and Dimitrios, T. and Dolan, J. and Duong, C. and Egberts, J.-H. and Elgharably, Y. and Elhadi, M. and Elmahi, S. and Farias, F.A. and Fekaj, E. and Fernández, J. and Forshaw, M. and Freire, J. and French, D. and Gacevski, G. and Gaedcke, J. and Gananadha, S. and Gijon, M.M. and Gokhale, J. and Gordon, A. and Grimminger, P. and Guevara, R. and Guner, A. and Gutknecht, S. and Mahmoodzadeh, H. and Halldestam, I. and Hedberg, J. and Heisterkamp, J. and Higgs, S. and Hii, M. and Hindmarsh, A. and Hoppner, J. and Isaza, A. and Izbicki, J. and Jacobs, R. and Jain, P. and Johansson, J. and Johnston, B. and Kafsi, J. and Kassa, S. and Kelty, C. and Khan, I. and Khoo, D. and Khyatt, S. and Kjaer, D. and Korkolis, D. and Kreuser, N. and Larsen, M. and Lau, P. and Leite, J. and Lewis, W. and Liakakos, T. and Loureiro, C. and Mahendran, A. and Maynard, N. and Mcgregor, R. and Mcnally, S. and Medina-Franco, H. and Meguid, R. and Melhado, R. and Mercer, S. and Migliore, M. and Mingol, F. and Mogoanta, S. and Mohri, Y. and Mönig, S. and Moreno, J. and Motas, N. and Murphy, T. and Naqi, S. and Ni, R. and Niazi, S. and Oglesby, S. and Okonta, K. and Ortiz, S.R. and Pal, K. and Palazzo, F. and Pascher, A. and Pascual, M. and Pata, G. and Pera, M. and Puig, S. and Ramirez, J. and Raptis, D. and RÀsÀnen, J. and Reim, D. and Reynolds, J. and Robb, W. and Robertson, K. and Rosero, G. and Rosman, C. and Rossaak, J. and Saarnio, J. and Santiago, A. and Schiesser, M. and Scurtu, R.-R. and Sekhniaidze, D. and Sevinç, B. and Skipworth, R. and So, J. and Trugeda, M.S. and Syed, A. and Takahashi, A.M.L. and Takeda, F. and Talbot, M. and Tareen, M. and Terashima, M. and Testini, M. and Tewari, N. and Tez, M. and Thomas, M. and Tirnaksiz, M. and Tonini, V. and Tu, C.-C. and Turner, P. and Underwood, T. and Uzair, A. and Vallve-Bernal, M. and Valmasoni, M. and Vicente, C. and Videira, J.F. and Viswanath, Y. and Weindelmayer, J. and White, R. and Wigle, D. and Wilkerson, P. and Wills, V. and Zacharakis, E. and Zuluaga, M., International Variation in Surgical Practices in Units Performing Oesophagectomy for Oesophageal Cancer: A Unit Survey from the Oesophago-Gastric Anastomosis Audit (OGAA), World Journal of Surgery, 2019 Journal Article, 2019 DOI

Elliott, J.A. and Casey, S. and Murphy, C.F. and Docherty, N.G. and Ravi, N. and Beddy, P. and Reynolds, J.V. and le Roux, C.W., Risk factors for loss of bone mineral density after curative esophagectomy, Archives of Osteoporosis, 14, (1), 2019 Journal Article, 2019 DOI

Hussey J,Yang T, Dowds J, O'Connor L, Reynolds JV, Guinan EM, Quantifying postoperative mobilisation following oesphagectomy, Physiotherapy, 105, (1), 2019, p126 - 133 Journal Article, 2019

Guinan, E.M., Bennett, A.E., Doyle, S.L., O'Neill, L, Gannon, J., Foley, G., Elliott, J.A., O'Sullivan, J., Reynolds, J.V., & Hussey, J., Measuring the impact of oesophagectomy on physical functioning and physical activity participation: a prospective study, BMC Cancer, 19, (682), 2019 Journal Article, 2019 DOI URL TARA - Full Text

O'Neill, L.M., Bennett, A.E., Guinan, E., Reynolds, J.V., Hussey, J., Physical recovery in the first six months following oesophago-gastric cancer surgery. Identifying rehabilitative needs: a qualitative interview study, Disability and Rehabilitation, 2019, p1-8 Journal Article, 2019 DOI URL

Elliott J.A., Docherty N., Murphy C., Eckhardt H., Doyle S.L., Guinan E., Ravi N., Reynolds J.V., Le Roux C, Changes in gut hormones, glycaemic response and symptoms after oesophagectomy, British Journal of Surgery, 106, (6), 2019, p735 - 746 Journal Article, 2019 DOI

O'Neill L., Knapp P., Doyle SL., Guinan E., Parker A.,Segurado R., Connolly D., O'Sullivan J., Reynolds JV., Hussey J, 'Patient and family co-developed participant information to improve recruitment rates, retention, and patient understanding in the Rehabilitation Strategies Following Oesophago-gastric and Hepatopancreaticobiliary Cancer (ReStOre II) trial: Protocol for a study within a trial (SWAT) [version 1; peer review: awaiting peer review]', 2019, - Protocol or guideline, 2019 DOI

Toxopeus, E.L.A. and Lynam-Lennon, N. and Biermann, K. and Dickens, G. and de Ruiter, P.E. and van Lanschot, J.J.B. and Reynolds, J.V. and Wijnhoven, B.P.L. and O†Sullivan, J. and van der Laan, L.J.W., Tumor microRNA-126 controls cell viability and associates with poor survival in patients with esophageal adenocarcinoma, Experimental Biology and Medicine, 244, (14), 2019, p1210-1219 Journal Article, 2019 DOI

Hagens, E.R.C. and Van Berge Henegouwen, M.I. and Van Sandick, J.W. and Cuesta, M.A. and Van Der Peet, D.L. and Heisterkamp, J. and Nieuwenhuijzen, G.A.P. and Rosman, C. and Scheepers, J.J.G. and Sosef, M.N. and Van Hillegersberg, R. and Lagarde, S.M. and Nilsson, M. and RÀsÀnen, J. and Nafteux, P. and Pattyn, P. and Hölscher, A.H. and Schröder, W. and Schneider, P.M. and Mariette, C. and Castoro, C. and Bonavina, L. and Rosati, R. and De Manzoni, G. and Mattioli, S. and Garcia, J.R. and Pera, M. and Griffin, M. and Wilkerson, P. and Chaudry, M.A. and Sgromo, B. and Tucker, O. and Cheong, E. and Moorthy, K. and Walsh, T.N. and Reynolds, J. and Tachimori, Y. and Inoue, H. and Matsubara, H. and Kosugi, S.-I. and Chen, H. and Law, S.Y.K. and Pramesh, C.S. and Puntambekar, S.P. and Murthy, S. and Linden, P. and Hofstetter, W.L. and Kuppusamy, M.K. and Shen, K.R. and Darling, G.E. and Sabino, F.D. and Grimminger, P.P. and Meijer, S.L. and Bergman, J.J.G.H.M. and Hulshof, M.C.C.M. and Van Laarhoven, H.W.M. and Mearadji, B. and Bennink, R.J. and Annema, J.T. and Dijkgraaf, M.G.W. and Gisbertz, S.S., Distribution of lymph node metastases in esophageal carcinoma [TIGER study]: Study protocol of a multinational observational study, BMC Cancer, 19, (1), 2019 Journal Article, 2019 DOI

Elliott, J.A. and O'Byrne, L. and Foley, G. and Murphy, C.F. and Doyle, S.L. and King, S. and Guinan, E.M. and Ravi, N. and Reynolds, J.V., Effect of neoadjuvant chemoradiation on preoperative pulmonary physiology, postoperative respiratory complications and quality of life in patients with oesophageal cancer, British Journal of Surgery, 2019 Journal Article, 2019 DOI

Naoimh J. O'Farrell, James J. Phelan, Ronan Feighery, Brendan Doyle, Sarah L. Picardo, Ravi Narayanasamy, Dermot O'Toole, John V. Reynolds, Jacintha O'Sullivan, Differential expression profiles of oxidative stress levels, 8-oxo-dG and 4-HNE, in Barrett's esophagus compared to esophageal adenocarcinoma, International Journal of Molecular Sciences, 2019 Journal Article, 2019 DOI TARA - Full Text URL

Abdel-Latif, M. and Babar, M. and Kelleher, D. and Reynolds, J., A pilot study of the impact of Vitamin C supplementation with neoadjuvant chemoradiation on regulators of inflammation and carcinogenesis in esophageal cancer patients, Journal of Cancer Research and Therapeutics, 15, (1), 2019, p185-191 Journal Article, 2019 DOI

Kavanagh, M.E. and Conroy, M.J. and Clarke, N.E. and Gilmartin, N.T. and Feighery, R. and MacCarthy, F. and O†Toole, D. and Ravi, N. and Reynolds, J.V. and O†Sullivan, J. and Lysaght, J., Altered T Cell Migratory Capacity in the Progression from Barrett Oesophagus to Oesophageal Adenocarcinoma, Cancer Microenvironment, 2019 Journal Article, 2019 DOI

Mongan AM, Lynam-Lennon N, Doyle SL, Casey R, Carr E, Cannon A, Conroy MJ, Pidgeon GP, Brennan L, Lysaght J, Reynolds JV, O'Sullivan J., Visceral Adipose Tissue Modulates Radiosensitivity in Oesophageal Adenocarcinoma., International journal of medical sciences, 16, (4), 2019, p519-528 Journal Article, 2019 DOI TARA - Full Text

Buckley AM, Dunne MR, Lynam-Lennon N, Kennedy SA, Cannon A, Reynolds AL, Maher SG, Reynolds JV, Kennedy BN, O'Sullivan J., Pyrazinib (P3), [(E)-2-(2-Pyrazin-2-yl-vinyl)-phenol], a small molecule pyrazine compound enhances radiosensitivity in oesophageal adenocarcinoma., Cancer letters, 447, 2019, p115-129 Journal Article, 2019 DOI

Low, D.E. and Kuppusamy, M.K. and Alderson, D. and Cecconello, I. and Chang, A.C. and Darling, G. and Davies, A. and D'Journo, X.B. and Gisbertz, S.S. and Griffin, S.M. and Hardwick, R. and Hoelscher, A. and Hofstetter, W. and Jobe, B. and Kitagawa, Y. and Law, S. and Mariette, C. and Maynard, N. and Morse, C.R. and Nafteux, P. and Pera, M. and Pramesh, C.S. and Puig, S. and Reynolds, J.V. and Schroeder, W. and Smithers, M. and Wijnhoven, B.P.L., Benchmarking complications associated with esophagectomy, Annals of Surgery, 269, (2), 2019, p291-298 Journal Article, 2019 DOI

Donlon, N.E. and Boland, P.A. and Kelly, M.E. and Schmidt, K. and Cooke, F. and Neary, P.M. and Barry, K.M. and Reynolds, J.V., Prophylactic negative wound therapy in laparotomy wounds (PROPEL trial): randomized controlled trial, International Journal of Colorectal Disease, 34, (11), 2019, p2003-2010 Journal Article, 2019 DOI

Klevebro, F. and Elliott, J.A. and Slaman, A. and Vermeulen, B.D. and Kamiya, S. and Rosman, C. and Gisbertz, S.S. and Boshier, P.R. and Reynolds, J.V. and Rouvelas, I. and Hanna, G.B. and van Berge Henegouwen, M.I. and Markar, S.R., Cardiorespiratory Comorbidity and Postoperative Complications following Esophagectomy: a European Multicenter Cohort Study, Annals of Surgical Oncology, 26, (9), 2019, p2864-2873 Journal Article, 2019 DOI

O'Neill, L. and Moran, J. and Guinan, E.M. and Reynolds, J.V. and Hussey, J., Physical decline and its implications in the management of oesophageal and gastric cancer: a systematic review, Journal of Cancer Survivorship, 12, (4), 2018, p601 - 618 Journal Article, 2018 DOI

Baiocchi, G.L. and Giacopuzzi, S. and Marrelli, D. and Reim, D. and Piessen, G. and Matos da Costa, P. and Reynolds, J.V. and Meyer, H.-J. and Morgagni, P. and Gockel, I. and Lara Santos, L. and Jensen, L.S. and Murphy, T. and Preston, S.R. and Ter-Ovanesov, M. and Fumagalli Romario, U. and Degiuli, M. and Kielan, W. and Mönig, S. and KoÅ'odziejczyk, P. and Polkowski, W. and Hardwick, R. and Pera, M. and Johansson, J. and Schneider, P.M. and de Steur, W.O. and Gisbertz, S.S. and Hartgrink, H. and van Sandick, J.W. and Portolani, N. and Hölscher, A.H. and Botticini, M. and Roviello, F. and Mariette, C. and Allum, W. and de Manzoni, G., International consensus on a complications list after gastrectomy for cancer, Gastric Cancer, 2018, p1-18 Journal Article, 2018 DOI

Brookes, S.T. and Chalmers, K.A. and Avery, K.N.L. and Coulman, K. and Blazeby, J.M. and Alderson, D. and Whiting, J. and Alkhaffaf, B. and Allum, W. and Attwood, S. and Barr, H. and Hewin, D. and Higgs, S. and Vipond, M. and Batiwalla, I. and Blackshaw, G. and Bolter, M. and Goulding, C. and Berrisford, R. and Sanders, G. and Wheatley, T. and Botha, A. and Mason, R. and Byrne, J. and Kelly, J. and Callan, J. and Couper, G. and Deans, C. and Paterson-Brown, S. and Dawas, K. and Mughal, M. and Galloway, S. and George, M. and Gokhale, J. and Goodman, M. and Hardwick, R. and Hassn, A. and Henwood, M. and Kryzstopik, R. and Lewis, M. and Tallett, J. and MacKay, C. and Manson, J. and Moxon, R. and Osborne, S. and Page, R. and Shackcloth, M. and Parameswaran, R. and Parsons, S. and Welch, N. and Phillips, A. and Sgromo, B. and Preston, S. and Pursnani, K. and Ward, J. and Reynolds, J. and Titcomb, D. and Barham, C.P. and Falk, S. and Hollowood, A. and Tucker, O. and Underwood, T. and Vickers, J. and Walker, L. and Price, J. and Sedman, P. and Walsh, T. and Donovan, J. and Noble, S. and Elliott, J. and Goldin, R. and Hanna, G., Impact of question order on prioritisation of outcomes in the development of a core outcome set: A randomised controlled trial, Trials, 19, (1), 2018 Journal Article, 2018 DOI

Galvin KC, Conroy MJ, Doyle SL, Dunne MR, Fahey R, Foley E, O'Sullivan KE, Doherty DG, Geoghegan JG, Ravi N, O'Farrelly C, Reynolds JV, Lysaght J, Extratumoral PD-1 blockade does not perpetuate obesity-associated inflammation in esophageal adenocarcinoma, Cancer Letters, 418, 2018, 230 - 238 Journal Article, 2018 URL

Hussey JM, Yang T, Dowds J, O'Connor L, Reynolds JV, Guinan EM., Quantifying postoperative mobilisation following oesophagectomy., Physiotherapy, 105, (1), 2018, p126 - 133 Journal Article, 2018 DOI

O'Neill, L.M., Guinan, E., Doyle, S.L., Bennett, A.E., Murphy, C., Elliott, J.A., O'Sullivan, J., Reynolds, J.V., Hussey, J., The RESTORE Randomized Controlled Trial: Impact of a multidisciplinary rehabilitative program on cardiorespiratory fitness in esophagogastric cancer survivorship, Annals of Surgery, 268, (5), 2018, p747 - 755 Journal Article, 2018 DOI URL

O†sullivan, K.E. and Michielsen, A.J. and O†regan, E. and Cathcart, M.C. and Moore, G. and Breen, E. and Segurado, R. and Reynolds, J.V. and Lysaght, J. and O†sullivan, J., pSTAT3 levels have divergent expression patterns and associations with survival in squamous cell carcinoma and adenocarcinoma of the oesophagus, International Journal of Molecular Sciences, 19, (6), 2018, p1720- Journal Article, 2018 DOI TARA - Full Text

Bennett, A.E., O'Neill, L., Connolly, D., Guinan, E.M., Boland, L., Doyle, S.L., O'Sullivan, J., Reynolds, J.V., & Hussey, J., Patient experiences of a physiotherapy-led multidisciplinary rehabilitative intervention after successful treatment for oesophago-gastric cancer, Supportive Care in Cancer, 26, (8), 2018, p2615 - 2623 Journal Article, 2018 URL DOI

Sheil, F. and Donohoe, C.L. and King, S. and O†Toole, D. and Cunningham, M. and Cuffe, S. and Ravi, N. and Reynolds, J.V., Outcomes for Esophageal Squamous Cell Carcinoma Treated with Curative Intent in a Western Cohort: Should Multimodal Therapy Be the Gold Standard?, World Journal of Surgery, 2018, p1485-1495 Journal Article, 2018 DOI

Bell, A. and Conway, N. and Courtney, J. and Kennedy, K. and Raubenheimer, Z. and Rice, N. and Kevans, D. and Donohoe, C.L. and Reynolds, J.V., Point prevalence of adult intestinal failure in Republic of Ireland, Irish Medical Journal, 111, (2), 2018, p688 Journal Article, 2018

Guinan EM, Forde C, O'Neill L, Gannon J, Doyle SL, Valkenet K, Trappenburg JCA, van Hillegersberg R, Ravi N, Hussey JM, Reynolds JV., Effect of preoperative inspiratory muscle training on physical functioning following esophagectomy., Diseases of the Esphagus, 32, (32), 2018, pdoy091- Journal Article, 2018 DOI

Valkenet, K. and Trappenburg, J.C.A. and Ruurda, J.P. and Guinan, E.M. and Reynolds, J.V. and Nafteux, P. and Fontaine, M. and Rodrigo, H.E. and van der Peet, D.L. and Hania, S.W. and Sosef, M.N. and Willms, J. and Rosman, C. and Pieters, H. and Scheepers, J.J.G. and Faber, T. and Kouwenhoven, E.A. and Tinselboer, M. and RÃ"sÃ"nen, J. and RyynÃ"nen, H. and Gosselink, R. and van Hillegersberg, R. and Backx, F.J.G., Multicentre randomized clinical trial of inspiratory muscle training versus usual care before surgery for oesophageal cancer, British Journal of Surgery, 105, (5), 2018, p502-511 Journal Article, 2018 DOI

Guinan, E.M., Doyle, S.L., Bennett, A.E., O'Neill, L, Gannon, J., Elliott, J.A., O'Sullivan, J., Reynolds, J.V., & Hussey, J., Sarcopenia during neoadjuvant therapy for oesophageal cancer: characterising the impact on muscle strength and physical performance, Supportive Care in Cancer, 26, (5), 2018, p1569 - 1576 Journal Article, 2018 DOI URL

Duggan, S.P. and Garry, C. and Behan, F.M. and Phipps, S. and Kudo, H. and Kirca, M. and Zaheer, A. and McGarrigle, S. and Reynolds, J.V. and Goldin, R. and Kalloger, S.E. and Schaeffer, D.F. and Long, A. and Strid, J. and Kelleher, D., siRNA Library Screening Identifies a Druggable Immune-Signature Driving Esophageal Adenocarcinoma Cell Growth, Cellular and Molecular Gastroenterology and Hepatology, 5, (4), 2018, p569-590 Journal Article, 2018 DOI TARA - Full Text

Reynolds, J.V. and Preston, S.R. and O'Neill, B. and Baeksgaard, L. and Griffin, S.M. and Mariette, C. and Cuffe, S. and Cunningham, M. and Crosby, T. and Parker, I. and Hofland, K. and Hanna, G. and Svendsen, L.B. and Donohoe, C.L. and Muldoon, C. and O'Toole, D. and Johnson, C. and Ravi, N. and Jones, G. and Corkhill, A.K. and Illsley, M. and Mellor, J. and Lee, K. and Dib, M. and Marchesin, V. and Cunnane, M. and Scott, K. and Lawner, P. and Warren, S. and O'Reilly, S. and O'Dowd, G. and Leonard, G. and Hennessy, B. and Dermott, R.M., ICORG 10-14: NEOadjuvant trial in Adenocarcinoma of the oEsophagus and oesophagoGastric junction International Study (Neo-AEGIS), BMC Cancer, 17, (1), 2017 Journal Article, 2017 DOI TARA - Full Text

Ahmed Z, Elliott J.A, King S, Donohoe C.L, Ravi N, Reynolds J.V, Risk Factors for Anastomotic Stricture Post-esophagectomy with a Standardized Sutured Anastomosis, World Journal of Surgery, 41, (2), 2017, p487 - 497 Journal Article, 2017 URL DOI

Guinan, E.M., Dowds, J., Donohoe, C., Reynolds, J.V., Hussey, J., The physiotherapist and the esophageal cancer patient: From prehabilitation to rehabilitation, Diseases of the Esophagus, 30, (1), 2017, p1-12 Journal Article, 2017 DOI

Dunne M., Michielsen A., O"Sullivan K., Cathcart M., Feighery R., Doyle B., Doyle B., Watson J., O"Farrell N., Ravi N., Kay E., Reynolds J., Ryan E., O"Sullivan J., HLA-DR expression in tumor epithelium is an independent prognostic indicator in esophageal adenocarcinoma patients, Cancer Immunology, Immunotherapy, 66, (7), 2017, p841-850 Journal Article, 2017 TARA - Full Text DOI

O'Neill L, Gannon J, Guinan E, Reynolds JV, Hussey J. , Multidisciplinary rehabilitation across the esophageal cancer journey, Journal of Thoracic Diseases, 9, (12), 2017, pE1140 - E1142 Journal Article, 2017 TARA - Full Text DOI

Gannon JA, Guinan EM, Doyle SL, Beddy P, Reynolds JV, Hussey J, Reduced fitness and physical functioning are long-term sequelae after curative treatment for esophageal cancer: a matched control study, Diseases of the Esophagus, 30, (8), 2017, p1 - 7 Journal Article, 2017

Healy, L.A. and Ryan, A. and Doyle, S.L. and Ní Bhuachalla, à .B. and Cushen, S. and Segurado, R. and Murphy, T. and Ravi, N. and Donohoe, C.L. and Reynolds, J.V., Does Prolonged Enteral Feeding with Supplemental Omega-3 Fatty Acids Impact on Recovery Post-esophagectomy, Annals of Surgery, 266, (5), 2017, p720-728 Journal Article, 2017 DOI

O†Brien H, Mohan H, Hare C.O, Reynolds J.V, Kenny R.A, Mind Over Matter? The Hidden Epidemic of Cognitive Dysfunction in the Older Surgical Patient, Annals of Surgery, 265, (4), 2017, p677-691 Journal Article, 2017 URL DOI

Brennan, M. and Fanning, M. and Granahan, A. and Doyle, S.L. and Donohoe, C.L. and Lawlor, P. and Ravi, N. and Reynolds, J.V., Small intestinal bacterial overgrowth in patients post major upper gastrointestinal cancer surgery, Diseases of the Esophagus, 30, (5), 2017 Journal Article, 2017 DOI

Linda O'Neill, Emer Guinan, Suzanne L Doyle, Jessie A. Elliott, Jacintha O'Sullivan, John V. Reynolds, Juliette Hussey, Rehabilitation Strategies following esophageal cancer (the ReStOre trial): a feasibility study, Diseases of the Esophagus, 30, (5), 2017, p1 - 8 Journal Article, 2017 DOI

Prichard David O, Byrne Anne Marie, Murphy James O, Reynolds John V, O'Sullivan Jacintha, Feighery Ronan, Doyle Brendan, Eldin Osama Sharaf, Finn Stephen P, Maguire Aoife, Duff Deirdre, Kelleher Dermot P, Long Aideen, Deoxycholic acid promotes development of gastroesophageal reflux disease and Barrett's oesophagus by modulating integrin-αv trafficking , Journal of cellular and molecular medicine , 21 , (12 ), 2017, p3612 - 3625 Journal Article, 2017 DOI TARA - Full Text URL

Donohoe C.L, Lysaght J, O'Sullivan J, Reynolds J.V, Emerging Concepts Linking Obesity with the Hallmarks of Cancer, Trends in Endocrinology and Metabolism, 28, (1), 2017, p46 - 62 Journal Article, 2017 URL DOI

Donohoe, C.L. and Reynolds, J.V., Neoadjuvant treatment of locally advanced esophageal and junctional cancer: The evidence-base, current key questions and clinical trials, Journal of Thoracic Disease, 9, 2017, pS697-S704 Journal Article, 2017 DOI

Widdowson W.M, McGowan A, Phelan J, Boran G, Reynolds J, Gibney J, Vascular disease is associated with the expression of genes for intestinal cholesterol transport and metabolism, Journal of Clinical Endocrinology and Metabolism, 102, (1), 2017, p326 - 335 Journal Article, 2017 DOI URL

Lynam-Lennon N, Heavey S, Sommerville G, Bibby BA, Ffrench B, Quinn J, Gasch C, O'Leary JJ, Gallagher MF, Reynolds JV, Maher SG, MicroRNA-17 is downregulated in esophageal adenocarcinoma cancer stem-like cells and promotes a radioresistant phenotype, Oncotarget, 8, (7), 2017, p11400 - 11413 Journal Article, 2017 DOI TARA - Full Text

Donohoe, C.L. and Healy, L.A. and Fanning, M. and Doyle, S.L. and Mc Hugh, A. and Moore, J. and Ravi, N. and Reynolds, J.V., Impact of supplemental home enteral feeding postesophagectomy on nutrition, body composition, quality of life, and patient satisfaction, Diseases of the Esophagus, 30, (9), 2017, p1-9 Journal Article, 2017 DOI

Elliott J.A., Doyle, S.L., Murphy C.F., King S., Guinan E.M., Beddy, P., Narayanasamy, R. (, Sarcopenia: Prevalence, and Impact on Operative and Oncologic Outcomes in the Multimodal Management of Locally Advanced Esophageal Cancer , Annals of Surgery, 266, (5), 2017, p822 - 830 Journal Article, 2017 DOI

Markar, S.R. and Noordman, B.J. and Mackenzie, H. and Findlay, J.M. and Boshier, P.R. and Ni, M. and Steyerberg, E.W. and van der Gaast, A. and Hulshof, M.C.C.M. and Maynard, N. and van Berge Henegouwen, M.I. and Wijnhoven, B.P.L. and Reynolds, J.V. and Van Lanschot, J.J.B. and Hanna, G.B., Multimodality treatment for esophageal adenocarcinoma: Multi-center propensity-score matched study, Annals of Oncology, 28, (3), 2017, p519-527 Journal Article, 2017 DOI

Elliott, J.A., Docherty, N.G., Eckhardt, H.-G., Doyle, S.L., Guinan, E.M., Ravi, N., Reynolds, J.V., Roux, C.W.L., Weight Loss, Satiety, and the Postprandial Gut Hormone Response After Esophagectomy: A Prospective Study, Annals of Surgery, 266, (1), 2016, p82 - 90 Journal Article, 2016 TARA - Full Text DOI

Messager M, de Steur W, Boelens P.G, Jensen L.S, Mariette C, Reynolds J.V, Osorio J, Pera M, Johansson J, KoÅ'odziejczyk P, Roviello F, De Manzoni G, Mönig S.P, Allum W.H, Description and analysis of clinical pathways for oesophago-gastric adenocarcinoma, in 10 European countries (the EURECCA upper gastro intestinal group â€" European Registration of Cancer Care), European Journal of Surgical Oncology, 42, (9), 2016, p1432 - 1447 Journal Article, 2016 DOI URL

Walsh S.M, Casey S, Kennedy R, Ravi N, Reynolds J.V, Does the modified Glasgow Prognostic Score (mGPS) have a prognostic role in esophageal cancer?, Journal of Surgical Oncology, 113, (7), 2016, p732 - 737 Journal Article, 2016 DOI URL

Donohoe C.L, Reynolds J.V, Letter to the Co-Editors-in-Chief, Radiotherapy and Oncology, Radiotherapy and Oncology, 118, (1), 2016, p215- Journal Article, 2016 URL DOI

Phelan JJ, Feighery R, Eldin OS, Meachair SÓ, Cannon A, Byrne R, MacCarthy F, O'Toole D, Reynolds JV, O'Sullivan J, Examining the connectivity between different cellular processes in the Barrett tissue microenvironment., Cancer letters, 371, (2), 2016, p334-46 Journal Article, 2016 DOI

Messager M, De Steur W.O, Van Sandick J.W, Reynolds J, Pera M, Mariette C, Hardwick R.H, Bastiaannet E, Boelens P.G, Van Develde C.J.H, Allum W.H, Variations among 5 European countries for curative treatment of resectable oesophageal and gastric cancer: A survey from the EURECCA Upper GI Group (EUropean REgistration of Cancer CAre), European Journal of Surgical Oncology, 42, (1), 2016, p116 - 122 Journal Article, 2016 DOI URL

Abdel-Latif M.M, Inoue H, Kelleher D, Reynolds J.V, Factors regulating nuclear factor-kappa B activation in esophageal cancer cells: Role of bile acids and acid, Journal of Cancer Research and Therapeutics, 12, (1), 2016, p364 - 373 Journal Article, 2016 DOI URL

Malik V, Johnston C, O'Toole D, Lucey J, O'Farrell N, Claxton Z, Reynolds J.V, Metabolic tumor volume provides complementary prognostic information to EUS staging in esophageal and junctional cancer, Dis Esophagus., 2016, p1= Journal Article, 2016 DOI URL

O'Farrell N.J, Feighery R, Picardo S.L, Lynam-Lennon N, Biniecka M, McGarrigle S.A, Phelan J.J, MacCarthy F, O'Toole D, Fox E.J, Ravi N, Reynolds J.V, O'Sullivan J, Changes in mitochondrial stability during the progression of the Barrett's esophagus disease sequence, BMC Cancer, 16, (1), 2016, p497- Journal Article, 2016 DOI URL TARA - Full Text

Lynam-Lennon N., Bibby B., Mongan A., Marignol L., Paxton C., Geiersbach K., Geiersbach K., Bronner M., Bronner M., O"Sullivan J., Reynolds J., Maher S., Maher S., Low MiR-187 expression promotes resistance to chemoradiation therapy in vitro and correlates with treatment failure in patients with esophageal adenocarcinoma, Molecular Medicine, 22, 2016, p388-397 Journal Article, 2016 DOI

Conroy M.J, Galvin K.C, Kavanagh M.E, Mongan A.M, Doyle S.L, Gilmartin N, O'Farrelly C, Reynolds J.V, Lysaght J, CCR1 antagonism attenuates T cell trafficking to omentum and liver in obesity-associated cancer, Immunology and Cell Biology, 94, (6), 2016, p531 - 537 Journal Article, 2016 URL DOI

Conroy M.J, Fitzgerald V, Doyle S.L, Channon S, Useckaite Z, Gilmartin N, O†Farrelly C, Ravi N, Reynolds J.V, Lysaght J, The microenvironment of visceral adipose tissue and liver alter natural killer cell viability and function, Journal of Leukocyte Biology, 100, (6), 2016, p1435 - 1442 Journal Article, 2016 DOI URL

Mongan A.M, Lynam-Lennon N, Casey R, Maher S, Pidgeon G, Reynolds J.V, O†Sullivan J, Erratum to: Visceral obesity stimulates anaphase bridge formation and spindle assembly checkpoint dysregulation in radioresistant oesophageal adenocarcinoma (Clin Transl Oncol, 10.1007/s12094-015-1411-y), Clinical and Translational Oncology, 18, (6), 2016, p651- Journal Article, 2016 DOI URL

Heneghan H.M, Donohoe C, Elliot J, Ahmed Z, Malik V, Ravi N, Reynolds J.V, Can CT-PET and endoscopic assessment PostNeoadjuvant Chemoradiotherapy predict residual disease in esophageal cancer?, Annals of Surgery, 264, (5), 2016, p831 - 838 Journal Article, 2016 DOI URL

Conroy M.J, Galvin K.C, Doyle S.L, Kavanagh M.E, Mongan A.-M, Cannon A, Moore G.Y, Reynolds J.V, Lysaght J, Parallel Profiles of Inflammatory and Effector Memory T Cells in Visceral Fat and Liver of Obesity-Associated Cancer Patients, Inflammation, 39, (5), 2016, p1729 - 1736 Journal Article, 2016 DOI URL

Guinan, E.M., Doyle, S.L., O'Neill, L., Dunne, M.R., Foley, E.K., O'Sullivan, J., Reynolds, J.V., Hussey, J., Effects of a multimodal rehabilitation programme on inflammation and oxidative stress in oesophageal cancer survivors: the ReStOre feasibility study, Supportive Care in Cancer, 25, (3), 2016, p749 - 756 Journal Article, 2016 DOI

Kavanagh ME, Conroy MJ, Clarke NE, Gilmartin NT, O'Sullivan KE, Feighery R, MacCarthy F, O'Toole D, Ravi N, Reynolds JV, O'Sullivan J, Lysaght J, Impact of the inflammatory microenvironment on T-cell phenotype in the progression from reflux oesophagitis to Barrett oesophagus and oesophageal adenocarcinoma., Cancer letters, 370, (1), 2016, p117-24 Journal Article, 2016 DOI

Duggan S.P, Behan F.M, Kirca M, Zaheer A, McGarrigle S.A, Reynolds J.V, Vaz G.M.F, Senge M.O, Kelleher D, The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival, Scientific Reports, 6, 2016, p32638 - Journal Article, 2016 TARA - Full Text DOI URL

Elliott J.A, Reynolds J.V, le Roux C.W, Docherty N.G, Physiology, pathophysiology and therapeutic implications of enteroendocrine control of food intake, Expert Review of Endocrinology and Metabolism, 11, (6), 2016, p475 - 499 Journal Article, 2016 DOI URL

Mongan AM, Kalachand R, King S, O'Farrell NJ, Power D, Ravi N, Muldoon C, O'Byrne K, Reynolds JV, Outcomes in gastric and junctional cancer using neoadjuvant and adjuvant chemotherapy (epirubicin, oxaliplatin, and capecitabine) and radical surgery., Irish journal of medical science, 184, (2), 2015, p417-423 Journal Article, 2015 DOI

Elliott J.A, Jackson S, King S, Mchugh R, Docherty N.G, Reynolds J.V, Le Roux C.W, Gut hormone suppression increases food intake after esophagectomy with gastric conduit reconstruction, Annals of Surgery, 262, (5), 2015, p824 - 830 Journal Article, 2015 URL DOI

Low DE, Alderson D, Cecconello I, Chang AC, Darling GE, D"Journo XB, Griffin SM, Hölscher AH, Hofstetter WL, Jobe BA, Kitagawa Y, Kucharczuk JC, Law SY, Lerut TE, Maynard N, Pera M, Peters JH, Pramesh CS, Reynolds JV, Smithers BM, van Lanschot JJ, International Consensus on Standardization of Data Collection for Complications Associated With Esophagectomy: Esophagectomy Complications Consensus Group (ECCG)., Annals of surgery, 262, (2), 2015, p286-94 Journal Article, 2015 DOI

Abdel-Latif MM, Kelleher D, Reynolds JV, Molecular mechanisms of constitutive and inducible NF-kappaB activation in oesophageal adenocarcinoma., European journal of cancer (Oxford, England : 1990), 51, (4), 2015, 464-472 Journal Article, 2015 DOI

Anne-Marie Byrne , Spiros Bekiaris, Gina Duggan, David Prichard, Murat Kirca, Stephen Finn, John V Reynolds, Dermot Kelleher and Aideen Long, Golgi phosphoprotein 2 (GOLPH2) is a novel bile acid-responsive modulator of oesophageal cell migration and invasion, British Journal of Cancer, 113, 2015, p1332-1342 Journal Article, 2015 DOI TARA - Full Text

Palles C, Chegwidden L, Li X, Findlay JM, Farnham G, Castro Giner F, Peppelenbosch MP, Kovac M, Adams CL, Prenen H, Briggs S, Harrison R, Sanders S, MacDonald D, Haigh C, Tucker A, Love S, Nanji M, deCaestecker J, Ferry D, Rathbone B, Hapeshi J, Barr H, Moayyedi P, Watson P, Zietek B, Maroo N, Gay L, Underwood T, Boulter L, McMurtry H, Monk D, Patel P, Ragunath K, Al Dulaimi D, Murray I, Koss K, Veitch A, Trudgill N, Nwokolo C, Rembacken B, Atherfold P, Green E, Ang Y, Kuipers EJ, Chow W, Paterson S, Kadri S, Beales I, Grimley C, Mullins P, Beckett C, Farrant M, Dixon A, Kelly S, Johnson M, Wajed S, Dhar A, Sawyer E, Roylance R, Onstad L, Gammon MD, Corley DA, Shaheen NJ, Bird NC, Hardie LJ, Reid BJ, Ye W, Liu G, Romero Y, Bernstein L, Wu AH, Casson AG, Fitzgerald R, Whiteman DC, Risch HA, Levine DM, Vaughan TL, Verhaar AP, van den Brande J, Toxopeus EL, Spaander MC, Wijnhoven BP, van der Laan LJ, Krishnadath K, Wijmenga C, Trynka G, McManus R, Reynolds JV, O'Sullivan J, MacMathuna P, McGarrigle SA, Kelleher D, Vermeire S, Cleynen I, Bisschops R, Tomlinson I, Jankowski J, Polymorphisms Near TBX5 and GDF7 Are Associated With Increased Risk for Barrett's Esophagus., Gastroenterology, 148, (2), 2015, p367-78 Journal Article, 2015 DOI TARA - Full Text

Donohoe C.L, Conneely J.B, Zilbert N, Hennessy M, Schofield S, Reynolds J.V, Docemur Docemus: Peer-Assisted Learning Improves the Knowledge Gain of Tutors in the Highest Quartile of Achievement but Not Those in the Lowest Quartile, Journal of Surgical Education, 72, (6), 2015, p1139 - 1144 Journal Article, 2015 DOI URL

Heckel L, Fennell K.M, Reynolds J, Osborne R.H, Chirgwin J, Botti M, Ashley D.M, Livingston P.M, Unmet needs and depression among carers of people newly diagnosed with cancer, European Journal of Cancer, 51, (14), 2015, p2049 - 2057 Journal Article, 2015 URL DOI

Croghan, S., McCormack, O., Muldoon, C., Ravi, N., Reynolds, J.V., Metachronous adenocarcinoma of the remnant oesophagus 15 years following multimodal therapy, Irish Medical Journal, 108, (1), 2015, p22-3 Journal Article, 2015

Walsh S.M, Maphango N, Egan J.J, Reynolds J.V, Successful surgical management of early esophageal cancer in a patient with cystic fibrosis post-bilateral lung transplantation, BMJ case reports, 2015, 2015, p210342- Journal Article, 2015 URL DOI

Malik V, Harmon M, Johnston C, Fagan A.J, Claxton Z, Ravi N, O''Toole D, Muldoon C, Keogan M, Reynolds J.V, Meaney J.F.M, Whole Body MRI in the Staging of Esophageal Cancer-A Prospective Comparison with Whole Body <sup>18</sup>F-FDG PET-CT, Digestive Surgery, 32, (5), 2015, p397 - 408 Journal Article, 2015 URL DOI

Picardo SL, O'Brien MP, Feighery R, O'Toole D, Ravi N, O'Farrell NJ, O'Sullivan JN, Reynolds JV, A Barrett's esophagus registry of over 1000 patients from a specialist center highlights greater risk of progression than population-based registries and high risk of low grade dysplasia., Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E, 28, (2), 2015, p121-126 Journal Article, 2015 DOI TARA - Full Text

Elliott J.A, Donohoe C.L, Reynolds J.V, Obesity and increased risk of esophageal adenocarcinoma, Expert Review of Endocrinology and Metabolism, 10, (5), 2015, p511 - 523 Journal Article, 2015 DOI URL

El-Mashed S., O'Donovan T., Kay E., Abdallah A., Cathcart M., O'Sullivan J., O'Grady A., Reynolds J., O'Reilly S., O'Sullivan G., McKenna S., LC3B globular structures correlate with survival in esophageal adenocarcinoma, BMC Cancer, 15, (1), 2015, p582- Journal Article, 2015 DOI TARA - Full Text

Bibby B.A.S, Reynolds J.V, Maher S.G, MicroRNA-330-5p as a putative modulator of neoadjuvant chemoradiotherapy sensitivity in oesophageal adenocarcinoma, PLoS ONE, 10, (7), 2015, p013418- Journal Article, 2015 TARA - Full Text URL DOI

Conroy MJ, Dunne MR, Donohoe CL, Reynolds JV, Obesity-associated cancer: an immunological perspective, Proceedings of the Nutrition Society, 2015, p1-14 Journal Article, 2015 URL Other

Heneghan H.M, Zaborowski A, Fanning M, Mchugh A, Doyle S, Moore J, Ravi N, Reynolds J.V, Prospective study of malabsorption and malnutrition after esophageal and gastric cancer surgery, Annals of Surgery, 262, (5), 2015, p803 - 808 Journal Article, 2015 URL DOI

O'Sullivan KE, Phelan JJ, O'Hanlon C, Lysaght J, O'Sullivan JN, Reynolds JV., The role of inflammation in cancer of the esophagus., Expert Reviews Gastroenterology Hepatology, 8, (7), 2014, p749 - 760 Journal Article, 2014 DOI TARA - Full Text

Kavanagh ME, O'Sullivan KE, O'Hanlon C, O'Sullivan JN, Lysaght J, Reynolds JV, The esophagitis to adenocarcinoma sequence; the role of inflammation., Cancer letters, 345, (2), 2014, p182-9 Journal Article, 2014 DOI TARA - Full Text

Lynam-Lennon, N., Maher, S.G., Maguire, A., (...), Reynolds, J.V., O'Sullivan, J., Altered mitochondrial function and energy metabolism is associated with a radioresistant phenotype in oesophageal adenocarcinoma, PLoS ONE , 9, (6), 2014, pe100738- Journal Article, 2014 DOI TARA - Full Text

Horan M, Weitz A, Mc Cormack O, Muldoon C, Ravi N, Reynolds JV, Severe dysphagia, candidiasis, and an oesophageal mass, but over 50 biopsies negative for malignancy., Dysphagia, 29, (1), 2014, p109-12 Journal Article, 2014 DOI

de Steur, W. O. Henneman, D. Allum, W. H. Dikken, J. L. van Sandick, J. W. Reynolds, J. Mariette, C. Jensen, L. Johansson, J. Kolodziejczyk, P. Hardwick, R. H. van de Velde, C. J. H., Common data items in seven European oesophagogastric cancer surgery registries: Towards a European Upper GI Cancer Audit (EURECCA Upper GI), European Journal of Surgical Oncology (EJSO), 40, (3), 2014, p325 - 329 Journal Article, 2014 TARA - Full Text

Valkenet K., Trappenburg J.C., Gosselink R., Sosef M.N., Willms J., Rosman C., Pieters H., Scheepers J.J., de Heus S.T., Reynolds J.V., Guinan EM., Ruurda J.P., Rodrigo E.H., Nafteux P., Fontaine M., Kouwenhoven E.A., Kerkemeyer M., van der Peet D.L., Hania S.W., van Hillegersberg R., Backx F.J. , Preoperative inspiratory muscle training to prevent postoperative pulmonary complications in patients undergoing esophageal resection (the PREPARE study): study protocol for a randomized controlled trial, Trials, 15, (1), 2014, p144- Journal Article, 2014 TARA - Full Text

Mc Cormack O, Reynolds J.V, Intermittent facial flushing and diarrhea, New England Journal of Medicine, 371, (3), 2014, p260- Journal Article, 2014 DOI URL

Lynam-Lennon N, Connaughton R, Carr E, Mongan AM, O'Farrell NJ, Porter RK, Brennan L, Pidgeon GP, Lysaght J, Reynolds JV, O'Sullivan J, Excess visceral adiposity induces alterations in mitochondrial function and energy metabolism in esophageal adenocarcinoma., BMC cancer, 14, 2014, p907 Journal Article, 2014 DOI TARA - Full Text

Moran T, Lawlor P, Brennan M, Ravi N, Reynolds JV, Oesophageal manometry: 10-year audit from a specialist centre, and early experience with high-resolution manometry., Irish journal of medical science, 184, (2), 2014, p379-87 Journal Article, 2014 DOI TARA - Full Text

Mc Cormack O, Zaborowski A, King S, Healy L, Daly C, O"Farrell N, Donohoe CL, Ravi N, Reynolds JV, New-onset atrial fibrillation post-surgery for esophageal and junctional cancer: incidence, management, and impact on short- and long-term outcomes., Annals of surgery, 260, (5), 2014, p772-8; discussion 778 Journal Article, 2014 DOI

Mc Cormack O, Reynolds JV, Images in clinical medicine. Intermittent facial flushing and diarrhea., The New England journal of medicine, 371, (3), 2014, p260 Journal Article, 2014 TARA - Full Text DOI

Kavanagh, M.E., O'Sullivan, K.E., O'Hanlon, C., (...), Lysaght, J., Reynolds, J.V., The esophagitis to adenocarcinoma sequence; the role of inflammation, Cancer Letters, 345, (2), 2014, p182-189 Journal Article, 2014 DOI

Donohoe CL, Reynolds JV, Defining a successful esophagectomy., Annals of surgery, 259, (5), 2014, pe82 Journal Article, 2014 TARA - Full Text DOI

Howard JM, Cathcart MC, Healy L, Beddy P, Muldoon C, Pidgeon GP, Reynolds JV, Leptin and adiponectin receptor expression in oesophageal cancer., The British journal of surgery, 101, (6), 2014, p643-52 Journal Article, 2014 DOI TARA - Full Text

Lahiff C, Schilling C, Cathcart MC, Mulligan N, Doran P, Muldoon C, Murray D, Pidgeon GP, Reynolds JV, Macmathuna P, Prognostic significance of neuroepithelial transforming gene 1 in adenocarcinoma of the oesophagogastric junction., The British journal of surgery, 101, (2), 2014, p55-62 Journal Article, 2014 DOI TARA - Full Text

Lynam-Lennon N, Maher SG, Maguire A, Phelan J, Muldoon C, Reynolds JV, O'Sullivan J, Altered mitochondrial function and energy metabolism is associated with a radioresistant phenotype in oesophageal adenocarcinoma., PloS one, 9, (6), 2014, pe100738 Journal Article, 2014 TARA - Full Text DOI

Elliott JA, McCormack O, Tchrakian N, Conlon N, Ryan CE, Lim KT, Ullah N, Mahmud N, Ravi N, McKiernan S, Feighery C, Reynolds JV, Eosinophilic ascites with marked peripheral eosinophilia: a diagnostic challenge., European journal of gastroenterology & hepatology, 26, (4), 2014, p478-84 Journal Article, 2014 TARA - Full Text DOI

Elliott J.A, O'Farrell N.J, King S, Halpenny D, Malik V, Muldoon C, Johnston C, Reynolds J.V, Value of CT-PET after neoadjuvant chemoradiation in the prediction of histological tumour regression, nodal status and survival in oesophageal adenocarcinoma, British Journal of Surgery, 101, (13), 2014, p1702 - 1711 Journal Article, 2014 DOI URL

Valkenet K, Trappenburg JC, Gosselink R, Sosef MN, Willms J, Rosman C, Pieters H, Scheepers JJ, de Heus SC, Reynolds JV, Guinan E, Ruurda JP, Rodrigo EH, Nafteux P, Fontaine M, Kouwenhoven EA, Kerkemeyer M, van der Peet DL, Hania SW, van Hillegersberg R, Backx FJ, Preoperative inspiratory muscle training to prevent postoperative pulmonary complications in patients undergoing esophageal resection (PREPARE study): study protocol for a randomized controlled trial., Trials, 15, (1), 2014, p144 Journal Article, 2014 DOI TARA - Full Text

Nur MM, Finn S, Reynolds JV, Identification of potential therapeutic molecular targets preferentially expressed by esophageal cancer cells., Expert review of anticancer therapy, 14, (3), 2014, p267-9 Journal Article, 2014 DOI

. Donohoe CL, O'Farrell NJ, Doyle SL, Reynolds JV., The role of obesity in gastrointestinal cancer: evidence and opinion, Therap Adv Gastroenterol, 7, (1), 2014, p38-50 Journal Article, 2014 DOI TARA - Full Text

Phelan JJ, MacCarthy F, Feighery R, O'Farrell NJ, Lynam-Lennon N, Doyle B, O'Toole D, Ravi N, Reynolds JV, O'Sullivan J, Differential expression of mitochondrial energy metabolism profiles across the metaplasia-dysplasia-adenocarcinoma disease sequence in Barrett's oesophagus., Cancer letters, 354, (1), 2014, p122-31 Journal Article, 2014 TARA - Full Text DOI

Mongan, A.M., Kalachand, R., King, S., (...), O'Byrne, K., Reynolds, J.V. , Outcomes in gastric and junctional cancer using neoadjuvant and adjuvant chemotherapy (epirubicin, oxaliplatin, and capecitabine) and radical surgery, Irish Journal of Medical Science, 184, (2), 2014, p417-423 Journal Article, 2014 DOI

Da Mota, Benoit Fritsch, Virgile Varoquaux, Gaël Banaschewski, Tobias Barker, Gareth J. Bokde, Arun L. W. Bromberg, Uli Conrod, Patricia Gallinat, Jürgen Garavan, Hugh Martinot, Jean-Luc Nees, Frauke Paus, Tomas Pausova, Zdenka Rietschel, Marcella Smolka, Michael N. Ströhle, Andreas Frouin, Vincent Poline, Jean-Baptiste Thirion, Bertrand, Randomized parcellation based inference, NeuroImage, 2014 Journal Article, 2014

O'Sullivan KE, Reynolds JV, O'Hanlon C, O'Sullivan JN, Lysaght J, Could signal transducer and activator of transcription 3 be a therapeutic target in obesity-related gastrointestinal malignancy?, Journal of gastrointestinal cancer, 45, (1), 2014, p1-11 Journal Article, 2014 DOI

Fang Y, Chen X, Bajpai M, Verma A, Das KM, Souza RF, Garman KS, Donohoe CL, O'Farrell NJ, Reynolds JV, Dvorak K, Cellular origins and molecular mechanisms of Barrett's esophagus and esophageal adenocarcinoma., Annals of the New York Academy of Sciences, 1300, 2013, p187-99 Journal Article, 2013 DOI

Moriarity AR, Larkin JO, O'Sullivan KE, Ravi N, Reynolds JV, Spontaneous perforation of the esophagus in a patient with achalasia., The Annals of thoracic surgery, 96, (4), 2013, p1456-7 Journal Article, 2013 DOI

Allott EH, Lysaght J, Cathcart MC, Donohoe CL, Cummins R, McGarrigle SA, Kay E, Reynolds JV, Pidgeon GP, MMP9 expression in oesophageal adenocarcinoma is upregulated with visceral obesity and is associated with poor tumour differentiation., Molecular carcinogenesis, 52, (2), 2013, p144-54 Journal Article, 2013 DOI

O'Farrell NJ, Donohoe CL, Muldoon C, Costelloe JM, King S, Ravi N, Reynolds JV, Lack of Independent Significance of a Close (<1 mm) Circumferential Resection Margin Involvement in Esophageal and Junctional Cancer., Annals of surgical oncology, 20, (8), 2013, p2727-33 Journal Article, 2013 DOI

Mc Cormack O, Cooney JM, Doherty CP, Muldoon C, Reynolds JV, Paraneoplastic limbic encephalitis from esophagogastric squamous cell carcinoma successfully managed by radical gastrectomy., Surgery, 154, (3), 2013, p638-40 Journal Article, 2013 DOI

O'Sullivan KE, Moriarty AR, Larkin JO, Reynolds JV, Curative surgical management of isolated adrenal recurrence of oesophageal adenocarcinoma., BMJ case reports, 2013, 2013, p00-0 Journal Article, 2013 DOI

Costelloe J, Mc Cormack O, Reynolds JV, Dissecting intramural hematoma of the esophagus., Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E, 26, (3), 2013, p346 Journal Article, 2013 DOI TARA - Full Text

O'Farrell NJ, Malik V, Donohoe CL, Johnston C, Muldoon C, Reynolds JV, O'Toole D, Appraisal of staging endoscopic ultrasonography in a modern high-volume esophageal program., World journal of surgery, 37, (7), 2013, p1666-72 Journal Article, 2013 DOI

Martin-Smith JD, Larkin JO, Ravi N, Reynolds JV, Severe epigastric pain following a birthday party., Irish medical journal, 106, (1), 2013, p23 Journal Article, 2013 TARA - Full Text

McCarron E, McCormack O, Cronin T, McGowan A, Healy ML, O'Rourke D, Crushell E, Ravi N, Reynolds JV, Management of maple syrup urine disease in the peri-operative period., Irish medical journal, 106, (9), 2013, p277-8 Journal Article, 2013 TARA - Full Text

Mc Cormack O, Meaney JF, Reynolds JV, Resolving sclerosing mesenteritis., Surgery, 153, (6), 2013, p879-80 Journal Article, 2013 DOI

Doyle SL, Bennett AM, Donohoe CL, Mongan AM, Howard JM, Lithander FE, Pidgeon GP, Reynolds JV, Lysaght J, Establishing computed tomography-defined visceral fat area thresholds for use in obesity-related cancer research., Nutrition research (New York, N.Y.), 33, (3), 2013, p171-9 Journal Article, 2013 DOI

Fitzgerald C, Mc Cormack O, Reynolds JV, Severe intractable postprandial chest pain., JAMA : the journal of the American Medical Association, 310, (4), 2013, p424-7 Journal Article, 2013 DOI

Fitzgerald C, Mc Cormack O, Awan F, Elliott J, Ravi N, Reynolds JV, Incarcerated thoracic gastric herniation after nephrectomy: a report of two cases., Case reports in surgery, 2013, 2013, p896452 Journal Article, 2013 DOI TARA - Full Text

Awan FN, Zulkifli MS, McCormack O, Manzoor T, Ravi N, Mehigan B, Reynolds JV, Factors involved in unplanned admissions from general surgical day-care in a modern protected facility., Irish medical journal, 106, (5), 2013, p153-4 Journal Article, 2013 TARA - Full Text

Donohoe CL, O'Farrell NJ, Grant T, King S, Clarke L, Muldoon C, Reynolds JV, Classification of pathologic response to neoadjuvant therapy in esophageal and junctional cancer: assessment of existing measures and proposal of a novel 3-point standard., Annals of surgery, 258, (5), 2013, p784-92; discussion 792 Journal Article, 2013 DOI

O'Farrell NJ, Reynolds JV, Ravi N, Larkin JO, Malik V, Wilson GF, Muldoon C, O'Toole D, Evolving changes in the management of early oesophageal adenocarcinoma in a tertiary centre., Irish journal of medical science, 182, (3), 2013, p363-9 Journal Article, 2013 DOI

Donohoe CL, Reynolds JV, Oesophageal Perforations Commentary., Digestive surgery, 30, (1), 2013, p26-27 Journal Article, 2013 DOI

Guevara G, O'Connor E, McCormack O, Harmon M, Finn S, Muldoon C, Ravi N, Reynolds JV, Diffuse oesophageal leiomyomatosis., ANZ journal of surgery, 2013 Journal Article, 2013 TARA - Full Text DOI

DeVault K, McMahon BP, Celebi A, Costamagna G, Marchese M, Clarke JO, Hejazi RA, McCallum RW, Savarino V, Zentilin P, Savarino E, Thomson M, Souza RF, Donohoe CL, O'Farrell NJ, Reynolds JV, Defining esophageal landmarks, gastroesophageal reflux disease, and Barrett's esophagus., Annals of the New York Academy of Sciences, 1300, 2013, p278-95 Review Article, 2013 DOI

O'Sullivan KE, Larkin JO, Guiney M, Reynolds JV, Necrotising pancreatitis presenting as a painful mass in the groin and sepsis., BMJ case reports, 2013, 2013 Journal Article, 2013 DOI

Mongan AM, Malik V, Rowley S, Claxton Z, Muldoon C, O'Toole D, Ravi N, Reynolds JV, Presentation and management of gastrointestinal stromal tumours., Irish medical journal, 106, (6), 2013, p176-9 Journal Article, 2013 TARA - Full Text

Costelloe J, O'Connell C, Mc Cormack O, Maccarthy F, Halpenny DF, Shatwan R, Muldoon C, Ravi N, Reynolds JV, Malignant Gastrocolic Fistula as a Late Complication of Radiation Therapy., Journal of gastrointestinal cancer, 43, (SUPPL. 1), 2012, pS269-S272 Journal Article, 2012 DOI

Mc Cormack O, Timlin M, Mc Gowan A, Healy ML, Ravi N, Reynolds JV, Management of squamous cell cancer of the oesophagus in a patient with a polyglandular endocrinopathy (APECED) and achalasia., Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 16, (10), 2012, p1963-6 Journal Article, 2012 DOI

Picardo SL, Maher SG, O'Sullivan JN, Reynolds JV, Barrett's to oesophageal cancer sequence: a model of inflammatory-driven upper gastrointestinal cancer., Digestive surgery, 29, (3), 2012, p251-60 Journal Article, 2012 DOI

Mary-Clare Cathcart, Kenneth J. O'Byrne, John V. Reynolds, Jacintha O' Sullivan, Graham P. Pidgeon, COX-Derived prostanoid pathways in gastrointestinal cancer development and progression: Novel targets for prevention and intervention, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1825, (1), 2012, p49-63 Journal Article, 2012 TARA - Full Text

Allott EH, Oliver E, Lysaght J, Gray SG, Reynolds JV, Roche HM, Pidgeon GP, The SGBS cell strain as a model for the in vitro study of obesity and cancer., Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 14, (10), 2012, p774-82 Journal Article, 2012 DOI

Donohoe CL, Doyle SL, McGarrigle S, Cathcart MC, Daly E, O'Grady A, Lysaght J, Pidgeon GP, Reynolds JV., Role of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma, British Journal of Surgery, 99, (3), 2012, p387-96 Journal Article, 2012 DOI

Lahiff C, Shields W, Cretu I, Mahmud N, McKiernan S, Norris S, Silke B, Reynolds JV, O'Toole D., Upper gastrointestinal bleeding: predictors of risk in a mixed patient group including variceal and nonvariceal haemorrhage, European Journal of Gastroenterology & Hepatology, 24, (2), 2012, p149-54 Journal Article, 2012 DOI

Reynolds JV, Donohore CL, McGillycuddy E, Ravi N, O'Toole D, O'Byrne K, Hollwyood D. , Evolving progress in oncologic and operative outcomes for esophageal and junctional cancer: Lessons from the experience of a high-volume esophageal center, The Journal of Thoracic and Cardiovascular Surgery, 145, (3), 2012, p1130-1137 Journal Article, 2012 DOI

Su Z, Gay LJ, Strange A, Palles C, Band G, Whiteman DC, Lescai F, Langford C, Nanji M, Edkins S, van der Winkel A, Levine D, Sasieni P, Bellenguez C, Howarth K, Freeman C, Trudgill N, Tucker AT, Pirinen M, Peppelenbosch MP, van der Laan LJ, Kuipers EJ, Drenth JP, Peters WH, Reynolds JV, Kelleher DP, McManus R, Grabsch H, Prenen H, Bisschops R, Krishnadath K, Siersema PD, van Baal JW, Middleton M, Petty R, Gillies R, Burch N, Bhandari P, Paterson S, Edwards C, Penman I, Vaidya K, Ang Y, Murray I, Patel P, Ye W, Mullins P, Wu AH, Bird NC, Dallal H, Shaheen NJ, Murray LJ, Koss K, Bernstein L, Romero Y, Hardie LJ, Zhang R, Winter H, Corley DA, Panter S, Risch HA, Reid BJ, Sargeant I, Gammon MD, Smart H, Dhar A, McMurtry H, Ali H, Liu G, Casson AG, Chow WH, Rutter M, Tawil A, Morris D, Nwokolo C, Isaacs P, Rodgers C, Ragunath K, MacDonald C, Haigh C, Monk D, Davies G, Wajed S, Johnston D, Gibbons M, Cullen S, Church N, Langley R, Griffin M, Alderson D, Deloukas P, Hunt SE, Gray E, Dronov S, Potter SC, Tashakkori-Ghanbaria A, Anderson M, Brooks C, Blackwell JM, Bramon E, Brown MA, Casas JP, Corvin A, Duncanson A, Markus HS, Mathew CG, Palmer CN, Plomin R, Rautanen A, Sawcer SJ, Trembath RC, Viswanathan AC, Wood N, Trynka G, Wijmenga C, Cazier JB, Atherfold P, Nicholson AM, Gellatly NL, Glancy D, Cooper SC, Cunningham D, Lind T, Hapeshi J, Ferry D, Rathbone B, Brown J, Love S, Attwood S, MacGregor S, Watson P, Sanders S, Ek W, Harrison RF, Moayyedi P, de Caestecker J, Barr H, Stupka E, Vaughan TL, Peltonen L, Spencer CC, Tomlinson I, Donnelly P, Jankowski JA, Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus., Nature genetics, 44, (10), 2012, p1131-6 Journal Article, 2012 DOI

Malik V, Johnston C, Donohoe C, Claxton Z, Lucey J, Ravi N, Reynolds JV, (18)F-FDG PET-detected synchronous primary neoplasms in the staging of esophageal cancer: incidence, cost, and impact on management., Clinical nuclear medicine, 37, (12), 2012, p1152-8 Journal Article, 2012 DOI

Babar M, Ryan AW, Anderson LA, Segurado R, Turner G, Murray LJ, Murphy SJ, Johnston BT, Comber H, Reynolds JV, McManus R, Genes of the Interleukin-18 pathway are associated with susceptibility to Barrett's Esophagus and Esophageal Adenocarcinoma, American Journal of Gastroenterology, 107, (9), 2012, p1331-1341 Journal Article, 2012 DOI

Crosby DA, Donohoe CL, Fitzgerald L, Muldoon C, Hayes B, O'Toole D, Reynolds JV, Gastric neuroendocrine tumours., Digestive surgery, 29, (4), 2012, p331-48 Journal Article, 2012 DOI

O'Flaherty JD, Barr M, Fennell D, Richard D, Reynolds J, O'Leary J, O'Byrne K, The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy., Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 7, (12), 2012, p1880-90 Journal Article, 2012 DOI

Donohoe CL, O'Farrell NJ, Ravi N, Reynolds JV, Evidence-based selective application of transhiatal esophagectomy in a high-volume esophageal center., World journal of surgery, 36, (1), 2012, p98-103 Journal Article, 2012 DOI

Donohoe CL, Feeney C, Carey MF, Reynolds JV., Perioperative evaluation of the obese patient, Journal of Clinical Anesthesia, 2012 Review Article, 2012

Ryan, A.M. , Healy, L.A., Reynolds, J.V. , Reply to letter, questions about the evidence regarding the benefits of enteral nutrition enriched with eicosapentaenoic acid in esophageal cancer surgery, 2012, - e16 Miscellaneous, 2012 DOI

SL Doyle, C Donohoe, S Finn, J Howard, FE Lithander, JV Reynolds, G Pidgeon, J Lysaght , IGF-1 and its Receptor in Esophageal Cancer: Association with Adenocarcinoma and Visceral Obesity, American Journal of Gastroenterology, 107, 2012, p196 - 204 Journal Article, 2012 URL DOI

O'Kelly F, Lim KT, Hayes B, Shields W, Ravi N, Reynolds JV, The Houdini effect--an unusual case of blunt abdominal trauma resulting in perforative appendicitis., Irish medical journal, 105, (3), 2012, p86-7 Journal Article, 2012

Geoghegan AR, Donohoe CL, Reynolds JV, Acute intestinal failure in surgical patients: an audit of incidence, management, and outcomes in an Irish hospital, and compliance with ASGBI guidelines, 181, 4, 2012, p467-71 Journal Article, 2012 DOI

Iland HJ, Bradstock K, Supple SG, Catalano A, Collins M, Hertzberg M, Browett P, Grigg A, Firkin F, Hugman A, Reynolds J, Di Iulio J, Tiley C, Taylor K, Filshie R, Seldon M, Taper J, Szer J, Moore J, Bashford J, Seymour JF, All-trans-retinoic acid, idarubicin, and IV arsenic trioxide as initial therapy in acute promyelocytic leukemia (APML4)., Blood, 120, (8), 2012, p1570-80; quiz 1752 Journal Article, 2012 DOI

Allott EH, Morine MJ, Lysaght J, McGarrigle SA, Donohoe CL, Reynolds JV, Roche HM, Pidgeon GP, Elevated Tumor Expression of PAI-1 and SNAI2 in Obese Esophageal Adenocarcinoma Patients and Impact on Prognosis., Clinical and translational gastroenterology, 3, 2012, pe12 Journal Article, 2012 TARA - Full Text DOI

Healy LA, Howard JM, Ryan AM, Beddy P, Mehigan B, Stephens R, Reynolds JV, Metabolic syndrome and leptin are associated with adverse pathological features in male colorectal cancer patients., Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 14, (2), 2012, p157-65 Journal Article, 2012 DOI

Naidoo J, O'Toole T, Kennedy MJ, Reynolds JV, A single institution experience of streptozotocin/fluorouracil combination chemotherapy: a case series, Irish Journal of Medical Science, 181, (2), 2012, p211-4 Journal Article, 2012 DOI

Hötte GJ, Linam-Lennon N, Reynolds JV, Maher SG, Radiation sensitivity of esophageal adenocarcinoma: the contribution of the RNA-binding protein RNPC1 and p21-mediated cell cycle arrest to radioresistance., Radiation research, 177, (3), 2012, p272-9 Journal Article, 2012 DOI

Doyle SL, Donohoe CL, Lysaght J, Reynolds JV, Viseral obesity, metabolic syndrome, insulin resistance and cancer, Proceedings of the Nutrition Society, 71, (1), 2012, p181-9 Journal Article, 2012 DOI

Maher SG, Reynolds JV, Basic concepts of inflammation and its role in carcinogenesis., Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer, 185, 2011, p1-34 Journal Article, 2011 DOI

Claire L. Donohoe, Aoife M. Ryan, and John V. Reynolds, Cancer Cachexia:Mechanisms and Clinical Implications, Gastroenterology Research and Practice, 2011, (601434), 2011, p13 Review Article, 2011 TARA - Full Text

Reynolds JV, Donohoe CL, Ravin N, O'Byrne K, Hollywood D., Modern operative and oncological outcome in oesophagel cancer, Irish Medical Journal, 104, 2011, p235-9 Journal Article, 2011 TARA - Full Text

Donohoe CL, Nguyen M, Cook J, Murray SG, Chen N, Zaki F, Mehigan BJ, McCormick PH, Reynolds JV, Fast-track protocols in colorectal surgery., The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland, 9, (2), 2011, p95-103 Journal Article, 2011 DOI

Larkin JO, Cooke F, Ravi N, Reynolds JV, Internal hernia following total gastrectomy with Roux-en-Y reconstruction., Annals of the Royal College of Surgeons of England, 93, (6), 2011, pe71-3 Journal Article, 2011 DOI TARA - Full Text

Reynolds JV, Donohoe CL, Doyle SL, Diet, obesity and cancer., Irish journal of medical science, 180, (2), 2011, p521-7 Journal Article, 2011 DOI

Mc Ardle A, Conneely JB, Ravi N, Reynolds JV, Duodenal duplication cyst presenting with gastric outlet obstruction in an adult male, Endoscopy, 43, 2011, pe352-3 Journal Article, 2011

Donohoe Cl, O'Farrell NJ, Ravi N, Reynolds JV, Evidence-based selective application of transhiatal esophagectomy in a high-volume esophageal center, World Journal of Surgery, 36, (1), 2011, p98-103 Journal Article, 2011 DOI

Paszko E, Ehrhardt C, Senge MO, Kelleher DP, Reynolds JV, Nanodrug applications in photodynamic therapy., Photodiagnosis and photodynamic therapy, 8, (1), 2011, p14-29 Journal Article, 2011 DOI TARA - Full Text

Donohoe CL, Doyle SL, Reynolds JV, Visceral adiposity, insulin resistance and cancer risk, Diabetology & Metabolic Syndrome , 3, (12), 2011 Journal Article, 2011 TARA - Full Text URL DOI

Philbin DM, Larkin JO, Ravi N, Wilson G, Reynolds JV, Recurrent melaena in a 21-year-old female., ANZ journal of surgery, 81, (3), 2011, p181-2 Journal Article, 2011 DOI

Howard JM, Ryan L, Lim KT, Reynolds JV, Oesophagectomy in the management of end-stage achalasia - case reports and a review of the literature., International journal of surgery (London, England), 9, (3), 2011, p204-8 Journal Article, 2011 DOI

Feeney C, Reynolds JV, Hussey J, Preoperative physical activity levels and postoperative pulmonary complications post-esphagectomy, Diseases of the Esophagus, 24, 2011, p489 - 494 Journal Article, 2011

Ryan AM, Duong M, Healy L, Ryan SA, Parekh N, Reynolds JV, Power DG, Obesity, metabolic syndrome and esophageal adenocarcinoma: epidemiology, etiology and new targets., Cancer epidemiology, 35, (4), 2011, p309-19 Journal Article, 2011 DOI

Stephen G. Maher, Dermot T. McDowell, Ben C. Collins, Cian Muldoon, William M. Gallagher, John V. Reynolds, Serum proteomic profiling reveals that pre-treatment complement protein levels are predictive of esophageal cancer patient response to neo-adjuvant chemoradiation, Annals of Surgery, 254, (5), 2011, p809 - 817 Journal Article, 2011

Donohoe CL, McGillycuddy E, Reynolds JV, Long-term health-related quality of life for disease-free esophageal cancer patients., World journal of surgery, 35, (8), 2011, p1853-60 Journal Article, 2011 DOI

Loh JK, O'Kelly F, Lim KT, Shields W, Ravi N, Keeling NP, Reynolds JV, Triple-vessel mesenteric ischaemia presenting with gastric ulceration., Irish journal of medical science, 180, (2), 2011, p537-40 Journal Article, 2011 DOI

J. Lysaght, E.P. van der Stok, E.H. Allott, R. Casey, C.L. Donohoe, J.M. Howard, S.A. McGarrigle, N. Ravi, J.V. Reynolds, G.P. Pidgeon, Pro-inflammatory and tumour proliferative properties of excess visceral adipose tissue, Cancer Letters, 312, (1), 2011, p62-72 Journal Article, 2011 TARA - Full Text

Mulholland HG, Murray LJ, Anderson LA, Cantwell MM, Vitamin D, calcium and dairy intake, and risk of oesophageal adenocarcinoma and its precursor conditions., The British journal of nutrition, 106, (5), 2011, p732-41 Journal Article, 2011 DOI TARA - Full Text

Lysaght J, Allott EH, Donohoe CL, Howard JM, Pidgeon GP, Reynolds JV., T lymphocyte activation in visceral adipose tissue of patients with oesophageal adenocarcinoma., British Journal of Surgery, 98, (7), 2011, p964 - 974 Journal Article, 2011 DOI

Donohoe CL, Macgillicuddy E, Reynolds JV, The impact of young age on outcomes in esophageal and junctional cancer, Diseases of the Esophagus, 24, (8), 2011, p560-568 Journal Article, 2011 DOI

Larkin JO, Moriarity AR, O'Mahony D, Meaney J, Ravi N, Reynolds JV, Gallstone ileus in evolution., ANZ journal of surgery, 81, (4), 2011, p287-8 Journal Article, 2011 DOI

Carroll PA, Healy L, Lysaght J, Boyle T, Reynolds JV, Kennedy MJ, Pidgeon G, Connolly EM., Influence of the metabolic syndrome on leptin and leptin receptor in breast cancer., Molecular Carcinogenesis, 50, (8), 2011, p643 - 651 Journal Article, 2011 DOI

O'Kelly F, Lim KT, Ravi N, Mahmud N, Reynolds JV, The value of double balloon enteroscopy in diagnosing blue rubber bleb naevus syndrome: a case report., Cases Journal, 3, (29), 2010 Journal Article, 2010 URL TARA - Full Text DOI

Healy LA, Ryan AM, Sutton E, Younger K, Mehigan B, Stephens R, Reynolds JV, Impact of obesity on surgical and oncological outcomes in the management of colorectal cancer., International journal of colorectal disease, 25, (11), 2010, p1293-9 Journal Article, 2010

Reynolds JV, Murphy TJ, Ravi N, Multimodality therapy for adenocarcinoma of the esophagus, gastric cardia, and upper gastric third., Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer, 182, 2010, p155-66 Journal Article, 2010

Murphy SJ, Anderson LA, Ferguson HR, Johnston BT, Watson PR, McGuigan J, Comber H, Reynolds JV, Murray LJ, Cantwell MM, Dietary antioxidant and mineral intake in humans is associated with reduced risk of esophageal adenocarcinoma but not reflux esophagitis or Barrett's esophagus., The Journal of nutrition, 140, (10), 2010, p1757-63 Journal Article, 2010

Power DG, Reynolds JV, Localized adenocarcinoma of the esophagogastric junction--is there a standard of care?, Cancer treatment reviews, 36, (5), 2010, p400-9 Journal Article, 2010

Beddy P, Howard J, McMahon C, Knox M, de Blacam C, Ravi N, Reynolds JV, Keogan MT, Association of visceral adiposity with oesophageal and junctional adenocarcinomas., The British journal of surgery, 97, (7), 2010, p1028-34 Journal Article, 2010

Howard JM, Beddy P, Ennis D, Keogan M, Pidgeon GP, Reynolds JV, Associations between leptin and adiponectin receptor upregulation, visceral obesity and tumour stage in oesophageal and junctional adenocarcinoma., The British journal of surgery, 97, (7), 2010, p1020-7 Journal Article, 2010

Donohoe CL, Reynolds JV, Short bowel syndrome , Surgeon, 8, 2010, p270-9 Journal Article, 2010

Duggan SP, Behan FM, Kirca M, Smith S, Reynolds JV, Long A, Kelleher D, An integrative genomic approach in oesophageal cells identifies TRB3 as a bile acid responsive gene, down regulated in Barrett's oesophagus, which regulates NF-kB activation and cytokine levels., Carcinogenesis, 5, 2010, p936 - 945 Journal Article, 2010 DOI URL

Reynolds JV, Ravi N, Muldoon C, Larkin JO, Rowley S, O'Byrne K, Hollywood D, O'Toole D, Differential pathologic variables and outcomes across the spectrum of adenocarcinoma of the esophagogastric junction., World journal of surgery, 34, (12), 2010, p2821-9 Journal Article, 2010 DOI

Byrne M, Reynolds JV, O'Donnell JS, Keogan M, White B, Byrne M, Murphy S, Maher SG, Pidgeon GP, Long-term activation of the pro-coagulant response after neoadjuvant chemoradiation and major cancer surgery., British Journal of Cancer, 102, (1), 2010, p73-9 Journal Article, 2010 DOI TARA - Full Text

Mary-Clare Cathcart, John V. Reynolds, Kenneth J. O'Byrne, Graham P. Pidgeon, The role of prostacyclin synthase and thromboxane synthase signaling in the development and progression of cancer , Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1805, (2), 2010, p153-166 Journal Article, 2010 TARA - Full Text

Healy LA, Ryan AM, Carroll P, Ennis D, Crowley V, Boyle T, Kennedy MJ, Connolly E, Reynolds JV., Metabolic syndrome, central obesity and insulin resistance are associated with adverse pathological features in postmenopausal breast cancer, Clinical Oncology, 22, (4), 2010, p281-288 Journal Article, 2010

Malik V, Lucey JA, Duffy GJ, Wilson L, McNamara L, Keogan M, Gillham C, Reynolds JV, Early repeated 18F-FDG PET scans during neoadjuvant chemoradiation fail to predict histopathologic response or survival benefit in adenocarcinoma of the esophagus., Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 51, (12), 2010, p1863-9 Journal Article, 2010

Howard JM, Pidgeon GP, Reynolds JV, Leptin and gastrointestinal malignancies , Obesity Reviews, 11, (12), 2010, p863-874 Journal Article, 2010

Lynam-Lennon N, Reynolds JV, Pidgeon GP, Lysaght J, Marignol L, Maher SG, Alterations in DNA repair efficiency are involved in the radioresistance of esophageal adenocarcinoma., Radiation research, 174, (6), 2010, p703 - 711 Journal Article, 2010 DOI

Doyle SL, Lysaght J, Reynolds JV, Obesity and post-operative complications in patients undergoing non-bariatric surgery., Obesity reviews : an official journal of the International Association for the Study of Obesity, 11, (12), 2010, p875-86 Journal Article, 2010 URL

O'Kelly F, Lim KT, Cooke F, Ravi N, Reynolds JV., An unusual presentation of Boerhaave Syndrome: a case report, Cases Journal, 2, (8000), 2009 Journal Article, 2009 DOI TARA - Full Text

Babar M, Abdel-Latif MM, Ravi N, Murphy A, Byrne PJ, Kelleher D, Reynolds JV., Pilot translational study of dietary vitamin C supplementation in Barrett's esophagus., Dis Esophagus, 23, (3), 2009 Journal Article, 2009

Martin-Smith JD, Larkin JO, O'Connell F, Ravi N, Reynolds JV , Management of gastro-bronchial fistula complicating a subtotal esophagectomy: a case report, BMC Surgery, 9, (20), 2009 Journal Article, 2009 DOI TARA - Full Text

Jayaprakash N, O'Kelly F, Lim KT, Reynolds JV., Management of synchronous adenocarcinoma of the esophago-gastric junction and ampulla of Vater: case report of a surgically challenging condition, Patient Safety in Surgery, 3, (23), 2009 Journal Article, 2009 TARA - Full Text DOI

Stephen G. Maher, Charles M. Gillham, Shane P. Duggan, Paul C. Smyth, Nicola Miller, Cian Muldoon, Kenneth J. O'Byrne, Orla M. Sheils, Donal Hollywood, John V. Reynolds, Gene expression analysis of diagnostic biopsies predicts pathological response to neoadjuvant chemoradiotherapy of esophageal cancer., Annals of surgery, 250, (5), 2009, p729-37 Journal Article, 2009 DOI

Smith FM, Gallagher WM, Fox E, Stephens RB, Rexhepaj E, Petricoin EF 3rd, Liotta L, Kennedy MJ, Reynolds JV, Combination of SELDI-TOF-MS and data mining provides early-stage response prediction for rectal tumors undergoing multimodal neoadjuvant therapy, Annals of Surgery, 245, (2), 2007, p259 - 266 Journal Article, 2007 URL

O'Riordan JM, Rowley S, Murphy JO, Ravi N, Byrne PJ, Reynolds JV, Impact of Solitary Involved Lymph Node on Outcome in Localized Cancer of the Esophagus and Esophagogastric Junction , Journal of Gastrointestinal Surgery, 11, (4), 2007, p493 - 499 Journal Article, 2007 URL

Smith FM, Reynolds JV, Miller N, Stephens RB, Kennedy MJ, Pathological and molecular predictors of the response of rectal cancer to neoadjuvant radiochemotherapy., European Journal of Surgical Oncology, 32, (1), 2006, p55 - 64 Journal Article, 2006 URL

Reynolds JV, McLaughlin R, Moore J, Rowley S, Ravi N, Byrne PJ. , Prospective evaluation of quality of life in patients with localized oesophageal cancer treated by multimodality therapy or surgery alone., The British Journal of Surgery, 93, (9), 2006, p1084 - 1090 Journal Article, 2006 URL

Mahmood Z, Byrne PJ, McMahon BP, Murphy EM, Arfin Q, Ravi N, Weir DG, Reynolds JV. , Comparison of transesophageal endoscopic plication (TEP) with laparoscopic Nissen fundoplication (LNF) in the treatment of uncomplicated reflux disease., The American Journal of Gastroenterology, 101, (3), 2006, p431 - 436 Journal Article, 2006 URL

Duggan SP, Gallagher WM, Fox EJ, Abdel-Latif MM, Reynolds JV, Kelleher D., Low pH results in co-ordinate regulation of gene expression in oesophageal cells, Carcinogenesis, 27, (2), 2006, p319 - 327 Journal Article, 2006 DOI TARA - Full Text

Gillham CM, Lucey JA, Keogan M, Duffy GJ, Malik V, Raouf AA, O'Byrne K, Hollywood D, Muldoon C, Reynolds JV, (18)FDG uptake during induction chemoradiation for oesophageal cancer fails to predict histomorphological tumour response., British Journal of Cancer, 95, (9), 2006, p1174 - 1179 Journal Article, 2006 URL

Ryan AM, Rowley SP, Healy LA, Flood PM, Ravi N, Reynolds JV. , Post-oesophagectomy early enteral nutrition via a needle catheter jejunostomy: 8-year experience at a specialist unit., Clinical Nutrition, 25, (3), 2006, p386 - 393 Journal Article, 2006 URL

Byrne PJ, Power C, Lawlor P, Ravi N, Reynolds JV, Laryngopharyngeal reflux in patients with symptoms of gastroesophageal reflux disease., Diseases of the Esophagus, 19, (5), 2006, p377 - 381 Journal Article, 2006 URL

Reynolds JV, Ravi N, Hollywood D, Kennedy Mj, Rowley S, Ryan A, Hughes N, Carey M, Byrne P, Neoadjuvant chemoradiation may increase the risk of respiratory complications and sepsis after transthoracic esophagectomy, Journal of Thoracic and Cardiovascular Surgery, 132, (3), 2006, p549 - 555 Journal Article, 2006 URL

MacGuill M, Mulligan E, Ravi N, Rowley S, Byrne PJ, Hollywood D, Kennedy J, Keeling PN, Reynolds JV. , Clinicopathologic factors predicting complete pathological response to neoadjuvant chemoradiotherapy in esophageal cancer., Diseases of the Esophagus, 19, (4), 2006, p273 - 276 Journal Article, 2006 URL

Ryan AM, Rowley SP, Fitzgerald AP, Ravi N, Reynolds JV. , Adenocarcinoma of the oesophagus and gastric cardia: male preponderance in association with obesity., European Journal of Cancer, 42, (8), 2006, p1151 - 1158 Journal Article, 2006 URL

Malik V, Keogan M, Gilham C, Duffy G, Ravi N, Reynolds JV, FDG-PET scanning in teh management of cancer of the oesophagus and oesophagogastric junction: early experience with 100 consecutive cases, Irish Journal of Medical Science, 175, (4), 2006, p48 - 54 Journal Article, 2006 URL

Anderson LA, Johnston BT, Watson RG, Murphy SJ, Ferguson HR, Comber H, McGuigan J, Reynolds JV, Murray LJ. , Nonsteroidal anti-inflammatory drugs and the esophageal inflammation-metaplasia-adenocarcinoma sequence., Cancer Research, 66, (9), 2006, p4975 - 4982 Journal Article, 2006 URL

Prichard R, Butt J, Al-Sariff N, Frohlich S, Murphy S, Manning B, Ravi N, Reynolds JV, Management of spontaneous rupture of the oesophagus (Boerhaave's syndrome): single centre experience of 18 cases, Irish Journal of Medical Science, 175, (4), 2006, p66 - 70 Journal Article, 2006 URL

Abdel-Latif MM, Windle H, Terres A, Eidhin DN, Kelleher D, Reynolds JV, Helicobacter pylori extract induces nuclear factor-kappa B, activator protein-1, and cyclooxygenase-2 in esophageal epithelial cells, Journal of Gastrointestinal Surgery, 10, (4), 2006, p551 - 562 Journal Article, 2006 URL

Ravi N, Stuart RC, Byrne PJ, Reynolds JV. , Effect of physical exercise on esophageal motility in patients with esophageal disease., Diseases of the Esophagus, 18, (6), 2005, p374 - 377 Journal Article, 2005 URL

Jabbar A, Reynolds JV, Plunkett PK, Stab to second intercostal space: a bubbling extrapleural wound., Èmergency Medicine Journal, 22, (12), 2005, p916 - 918 Journal Article, 2005 URL

Abdel-Latif MM, Raouf AA, Sabra K, Kelleher D, Reynolds JV, Vitamin C enhances chemosensitization of esophageal cancer cells in vitro, Journal of Chemotherapy, 17, (5), 2005, p539 - 549 Journal Article, 2005 URL

P. M. Lawlor, J. A. McCullough, P. J. Byrne and J. V. Reynolds, Gastric myoelectrical activity post-chemoradiotherapy and esophagectomy: a prospective study using subscapular surface recording, Diseases of the esophagus, 17, (1), 2004, p76-80 Journal Article, 2004 URL

J. M. O'Riordan, P. J. Byrne, N. Ravi, P. W. Keeling and J. V. Reynolds, Long-term clinical and pathologic response of Barrett's esophagus after antireflux surgery, American journal of surgery, 188, (1), 2004, p27-33 Journal Article, 2004 URL

J. M. O'Riordan, O. N. Tucker, P. J. Byrne, G. S. McDonald, N. Ravi, P. W. Keeling and J. V. Reynolds, Factors influencing the development of Barrett's epithelium in the esophageal remnant postesophagectomy, The American journal of gastroenterology, 99, (2), 2004, p205-11 Journal Article, 2004 URL

M. M. Abdel-Latif, J. O'Riordan, H. J. Windle, E. Carton, N. Ravi, D. Kelleher and J. V. Reynolds, NF-kappaB Activation in Esophageal Adenocarcinoma: Relationship to Barrett's Metaplasia, Survival, and Response to Neoadjuvant Chemoradiotherapy, Annals of surgery, 239, (4), 2004, p491-500 Journal Article, 2004 URL

E. D. Mulligan, B. Dunne, M. Griffin, N. Keeling and J. V. Reynolds, Margin involvement and outcome in oesophageal carcinoma: a 10-year experience in a specialist unit, European journal of surgical oncology, 30, (3), 2004, p313-7 Journal Article, 2004 URL

J. A. McCullough, D. Evoy, K. J. Sweeney, C. Meyers, N. Ravi, N. Keeling, P. J. Byrne and J. V. Reynolds, D2 lymphadenectomy in the management of gastric cancer, Irish journal of medical science, 172, (3), 2003, p132-5 Journal Article, 2003 URL

K. J. Sweeney, M. R. Kell, C. Coates, T. Murphy and J. V. Reynolds, Serum antigen(s) drive the proinflammatory T cell response in acute pancreatitis, The British journal of surgery, 90, (3), 2003, p313-9 Journal Article, 2003 URL

P. J. Byrne, E. D. Mulligan, J. O'Riordan, P. W. Keeling and J. V. Reynolds, Impaired visceral sensitivity to acid reflux in patients with Barrett's esophagus. The role of esophageal motility*, Diseases of the esophagus, 16, (3), 2003, p199-203 Journal Article, 2003 URL

A. A. Raouf, D. A. Evoy, E. Carton, E. Mulligan, M. M. Griffin and J. V. Reynolds, Loss of Bcl-2 expression in Barrett's dysplasia and adenocarcinoma is associated with tumor progression and worse survival but not with response to neoadjuvant chemoradiation, Diseases of the esophagus, 16, (1), 2003, p17-23 Journal Article, 2003 URL

Z. Mahmood, B. P. McMahon, Q. Arfin, P. J. Byrne, J. V. Reynolds, E. M. Murphy and D. G. Weir, Endocinch therapy for gastro-oesophageal reflux disease: a one year prospective follow up, Gut, 52, (1), 2003, p34-9 Journal Article, 2003 URL

E. M. Connolly, E. Gaffney and J. V. Reynolds, Gastrointestinal stromal tumours, The British journal of surgery, 90, (10), 2003, p1178-86 Journal Article, 2003 URL

K. J. Sweeney, D. Evoy, S. Sultan, C. Coates, D. J. Moore, D. G. Shanik, M. R. Kell and J. V. Reynolds, Endovascular approach to abdominal aortic aneurysms limits the postoperative systemic immune response, European journal of vascular and endovascular surgery, 23, (4), 2002, p303-8 Journal Article, 2002 URL

B. M. Ryan, R. McManus, J. S. Daly, E. Carton, P. W. Keeling, J. V. Reynolds and D. Kelleher, A common p73 polymorphism is associated with a reduced incidence of oesophageal carcinoma, British journal of cancer, 85, (10), 2001, p1499-503 Journal Article, 2001 URL

P. M. Lawlor, J. A. McCullough, P. J. Byrne and J. V. Reynolds, Electrogastrography: a non-invasive measurement of gastric function, Irish journal of medical science, 170, (2), 2001, p126-31 Journal Article, 2001 URL

J. P. McGrath, M. Browne, C. Riordan, N. Ravi and J. V. Reynolds, Expandable metal stents in the palliation of malignant dysphagia and oesophageal-respiratory fistulae, Irish medical journal, 94, (9), 2001, p270-2 Journal Article, 2001 URL

A. Raouf, D. Evoy, E. Carton, E. Mulligan, M. Griffin, E. Sweeney and J. V. Reynolds, Spontaneous and inducible apoptosis in oesophageal adenocarcinoma, British journal of cancer, 85, (11), 2001, p1781-6 Journal Article, 2001 URL

S. Kanwar, A. C. Windsor, F. Welsh, G. R. Barclay, P. J. Guillou and J. V. Reynolds, Lack of correlation between failure of gut barrier function and septic complications after major upper gastrointestinal surgery, Annals of surgery, 231, (1), 2000, p88-95 Journal Article, 2000 URL

E. D. Mulligan, T. Purcell, P. Lawlor, J. V. Reynolds and P. J. Byrne, Symptoms are a poor indication of severity of reflux in Barrett's oesophagus, The British journal of surgery, 87, (3), 2000, p362-73 Journal Article, 2000 URL

E. Carton, E. D. Mulligan, P. W. Keeling, A. Tanner, G. McDonald and J. V. Reynolds, Specialized intestinal metaplasia: analysis of prevalence, risk factors and association with gastro-oesophageal reflux disease, The British journal of surgery, 87, (3), 2000, p362-73 Journal Article, 2000 URL

K. J. Sweeney, I. Rowe, P. Lawlor, P. Byrne and J. V. Reynolds, The isolated hypertensive lower oesophageal sphincter: audit in a specialist unit, Irish medical journal, 93, (8), 2000, p232-4 Journal Article, 2000 URL

E. Carton, M. T. Caldwell, G. McDonald, D. Rama, W. A. Tanner and J. V. Reynolds, Specialized intestinal metaplasia in patients with gastro-oesophageal reflux disease, The British journal of surgery, 87, (1), 2000, p116-21 Journal Article, 2000 URL

S. Kanwar, A. Windsor and J. V. Reynolds, Early enteral nutrition in acute pancreatitis, Nutrition (Burbank, Los Angeles County, Calif), 15, (11-Dec), 1999, p951-2 Journal Article, 1999 URL

F. K. Welsh, C. W. Ramsden, K. MacLennan, M. B. Sheridan, G. R. Barclay, P. J. Guillou and J. V. Reynolds, Increased intestinal permeability and altered mucosal immunity in cholestatic jaundice, Annals of surgery, 227, (2), 1998, p205-12 Journal Article, 1998 URL

A. C. Windsor, S. Kanwar, A. G. Li, E. Barnes, J. A. Guthrie, J. I. Spark, F. Welsh, P. J. Guillou and J. V. Reynolds, Compared with parenteral nutrition, enteral feeding attenuates the acute phase response and improves disease severity in acute pancreatitis, Gut, 42, (3), 1998, p431-5 Journal Article, 1998 URL

F. K. Welsh, S. M. Farmery, K. MacLennan, M. B. Sheridan, G. R. Barclay, P. J. Guillou and J. V. Reynolds, Gut barrier function in malnourished patients, Gut, 42, (3), 1998, p396-401 Journal Article, 1998 URL

A. Klava, A. C. Windsor, S. M. Farmery, L. F. Woodhouse, J. V. Reynolds, C. W. Ramsden, A. W. Boylston and P. J. Guillou, Interleukin-10. A role in the development of postoperative immunosuppression, Archives of surgery (Chicago, Ill, 132, (4), 1997, p425-9 Journal Article, 1997 URL

J. Harbison, J. V. Reynolds, K. Sheahan, R. G. Gibney and J. M. Hyland, Evidence for the polyp-cancer sequence in gallbladder cancer, Irish medical journal, 90, (3), 1997, p98 Journal Article, 1997 URL

A. Blakeborough, R. G. McWilliams, U. Raja, P. J. Robinson, J. V. Reynolds and A. H. Chapman, Pseudolipoma of inverted Meckel's diverticulum: clinical, radiological and pathological correlation, European radiology, 7, (6), 1997, p900-4 Journal Article, 1997 URL

J. V. Reynolds, S. Kanwar, F. K. Welsh, A. C. Windsor, P. Murchan, G. R. Barclay and P. J. Guillou, 1997 Harry M. Vars Research Award. Does the route of feeding modify gut barrier function and clinical outcome in patients after major upper gastrointestinal surgery?, JPEN Journal of parenteral and enteral nutrition, 21, (4), 1997, p196-201 Journal Article, 1997 URL

A. Klava, A. Windsor, A. W. Boylston, J. V. Reynolds, C. W. Ramsden and P. J. Guillou, Monocyte activation after open and laparoscopic surgery, The British journal of surgery, 84, (8), 1997, p1152-6 Journal Article, 1997 URL

J. V. Reynolds, P. Murchan, N. Leonard, P. Clarke, F. B. Keane and W. A. Tanner, Gut barrier failure in experimental obstructive jaundice, The Journal of surgical research, 62, (1), 1996, p11-Jun Journal Article, 1996 URL

J. V. Reynolds, Gut barrier function in the surgical patient, The British journal of surgery, 83, (12), 1996, p1668-9 Journal Article, 1996 URL

J. V. Reynolds, C. O'Farrelly, C. Feighery, P. Murchan, N. Leonard, G. Fulton, C. O'Morain, F. B. Keane and W. A. Tanner, Impaired gut barrier function in malnourished patients, The British journal of surgery, 83, (9), 1996, p1288-91 Journal Article, 1996 URL

J. V. Reynolds, W. P. Joyce, J. Dolan, K. Sheahan and J. M. Hyland, Pathological evidence in support of total mesorectal excision in the management of rectal cancer, The British journal of surgery, 83, (8), 1996, p1112-5 Journal Article, 1996 URL

F. K. Welsh, S. M. Farmery, C. Ramsden, P. J. Guillou and J. V. Reynolds, Reversible impairment in monocyte major histocompatibility complex class II expression in malnourished surgical patients, JPEN Journal of parenteral and enteral nutrition, 20, (5), 1996, p344-8 Journal Article, 1996 URL

J. V. Reynolds, P. Murchan, N. Leonard, D. B. Gough, P. Clarke, F. B. Keane and W. A. Tanner, High-dose interleukin 2 promotes bacterial translocation from the gut, British journal of cancer, 72, (3), 1995, p634-6 Journal Article, 1995 URL

J. V. Reynolds and W. E. Enker, A simple, safe technique for stapled reconstruction after right hemicolectomy, Journal of the American College of Surgeons, 181, (2), 1995, p178-81 Journal Article, 1995 URL

J. V. Reynolds, K. Walsh, J. Ruigrok and J. M. Hyland, Randomised comparison of silicone versus Teflon cannulas for peripheral intravenous nutrition, Annals of the Royal College of Surgeons of England, 77, (6), 1995, p447-9 Journal Article, 1995 URL

J. V. Reynolds, P. Murchan, H. P. Redmond, R. W. Watson, N. Leonard, A. Hill, P. Clarke, P. Marks, F. B. Keane and W. A. Tanner, Failure of macrophage activation in experimental obstructive jaundice: association with bacterial translocation, The British journal of surgery, 82, (4), 1995, p534-8 Journal Article, 1995 URL

A. C. Windsor, S. S. Somers, A. Crellin, S. Hassan, R. Macadam, S. A. Sadek, P. J. Guillou and J. V. Reynolds, Paradoxical clinical deterioration despite near-complete pathological response to neoadjuvant chemotherapy for locally advanced gastro-oesophageal adenocarcinoma, Surgical oncology, 4, (5), 1995, p277-9 Journal Article, 1995 URL

A. C. Windsor, A. Klava, S. S. Somers, P. J. Guillou and J. V. Reynolds, Manipulation of local and systemic host defence in the prevention of perioperative sepsis, The British journal of surgery, 82, (11), 1995, p1460-7 Journal Article, 1995 URL

J. V. Reynolds, P. Mercer, E. W. McDermott, S. Cross, M. Stokes, D. Murphy and N. J. O'Higgins, Audit of complete axillary dissection in early breast cancer, European journal of cancer (Oxford, England, 30A, (2), 1994, p148-9 Journal Article, 1994 URL

G. J. Fulton, M. K. O'Donohoe, J. V. Reynolds, F. B. Keane and W. A. Tanner, Wedge resection alone or combined with segmental phenolization for the treatment of ingrowing toenail, The British journal of surgery, 81, (7), 1994, p1074-5 Journal Article, 1994 URL

J. V. Reynolds, J. P. Sweeney, N. Nolan, A. Korebrits, M. J. Duffy, E. W. McDermott and N. J. O'Higgins, Management of ductal carcinoma in situ of the breast, Irish journal of medical science, 162, (2), 1993, p45-8 Journal Article, 1993 URL

J. V. Reynolds, S. S. Somers and P. J. Guillou, Inhibition of interleukin-2 dependent immune responses by serum from patients with advanced gastrointestinal cancer, Surgical oncology, 2, (4), 1993, p227-34 Journal Article, 1993 URL

S. S. Somers, J. V. Reynolds and P. J. Guillou, Multifocal neurotoxicity during interleukin-2 therapy for malignant melanoma, Clinical oncology (Royal College of Radiologists (Great Britain)), 4, (2), 1992, p135-6 Journal Article, 1992 URL

J. V. Reynolds, H. P. Redmond, N. Ueno, C. Steigman, M. M. Ziegler, J. M. Daly and R. B. Johnston, Jr., Impairment of macrophage activation and granuloma formation by protein deprivation in mice, Cellular immunology, 139, (2), 1992, p493-504 Journal Article, 1992 URL

J. V. Reynolds and J. M. Galloway, Primary aortoduodenal fistula: a case report and review of the literature, Irish journal of medical science, 160, (12), 1991, p381-4 Journal Article, 1991 URL

R. K. Sigal, M. D. Lieberman, J. V. Reynolds, J. Shou, M. M. Ziegler and J. M. Daly, Low-dose interferon gamma renders neuroblastoma more susceptible to interleukin-2 immunotherapy, Journal of pediatric surgery, 26, (4), 1991, p389-95; discussion 395-6 Journal Article, 1991 URL

H. P. Redmond, P. Leon, M. D. Lieberman, K. Hofmann, J. Shou, J. V. Reynolds, J. Goldfine, R. B. Johnston, Jr. and J. M. Daly, Impaired macrophage function in severe protein-energy malnutrition, Archives of surgery (Chicago, Ill, 126, (2), 1991, p192-6 Journal Article, 1991 URL

Cambieri A, Muzii M, Catananti C, Candia L, [Hospitals and immigration: analysis of a case series]., Recenti progressi in medicina, 81, (7-8), 1991, p461-73 Journal Article, 1991

R. K. Sigal, M. D. Lieberman, J. V. Reynolds, N. Williams, M. M. Ziegler and J. M. Daly, Tumor immunization. Improved results after vaccine modified with recombinant interferon gamma, Archives of surgery (Chicago, Ill, 125, (3), 1990, p308-12 Journal Article, 1990 URL

J. V. Reynolds, J. M. Daly, J. Shou, R. Sigal, M. M. Ziegler and A. Naji, Immunologic effects of arginine supplementation in tumor-bearing and non-tumor-bearing hosts, Annals of surgery, 211, (2), 1990, p202-10 Journal Article, 1990 URL

J. V. Reynolds, J. A. Shou, R. Sigal, M. Ziegler and J. M. Daly, The influence of protein malnutrition on T cell, natural killer cell, and lymphokine-activated killer cell function, and on biological responsiveness to high-dose interleukin-2, Cellular immunology, 128, (2), 1990, p569-77 Journal Article, 1990 URL

J. V. Reynolds, J. Shou, H. Choi, R. Sigal, M. M. Ziegler and J. M. Daly, The influence of natural killer cells in neuroblastoma, Archives of surgery (Chicago, Ill, 124, (2), 1989, p235-9 Journal Article, 1989 URL

S. H. Choi, J. V. Reynolds and M. M. Ziegler, Systematic analysis of the immunoregulation of murine neuroblastoma, Journal of pediatric surgery, 24, (1), 1989, p15-9; Discussion 19-20 Journal Article, 1989 URL

J. V. Reynolds, A. K. Thom, S. M. Zhang, M. M. Ziegler, A. Naji and J. M. Daly, Arginine, protein malnutrition, and cancer, The Journal of surgical research, 45, (6), 1988, p513-22 Journal Article, 1988 URL

J. V. Reynolds, J. M. Daly, S. Zhang, E. Evantash, J. Shou, R. Sigal and M. M. Ziegler, Immunomodulatory mechanisms of arginine, Surgery, 104, (2), 1988, p142-51 Journal Article, 1988 URL

J. V. Reynolds, W. F. Kealy and G. C. O'Sullivan, Multiple pulmonary leiomyomatous hamartomas, Irish medical journal, 77, (4), 1984, p106-7 Journal Article, 1984 URL

Non-Peer-Reviewed Publications

Cliona M Lorton, John V Reynolds, Joanne Lysaght, ASO Author Reflections: Can CRP and CRP-Based Scores Predict Survival in Operable Adenocarcinomas of the Esophagus and Esophago-Gastric Junction?, Annals of Surgical Oncology, 2021 Journal Article, 2021

Research Expertise

Description

Anti-oxidants in inflammatory disease. Genetic polymorphisms in upper gastrointestinal cancer and Barrett's oesophagus. Liver and gut immune function in patients undergoing complex major surgery. Molecular predictors of response and resistance to chemotherapy and radiation therapy. Transcription factors in inflammation and neoplasia of the oesophagus. Upper gastrointestinal physiology.

Keywords

Anti-oxidants in inflammatory disease; Genetic polymorphisms in upper gastrointestinal cancer and Barrett's oesophagus; Liver and gut immune function in patients undergoing complex major surgery; Molecular predictors of response and resistance to chemotherapy and radiation therapy; Transcription factors in inflammation and neoplasia of the oesophagus; Upper gastrointestinal physiology

Recognition

Representations

Member, DMMC Inflammation, Immunity & Infection Principal Investigators, DMMC Principal Investigators leading research in inflammation, immunit and infection.

Member, Centre for Molecular Research in Cancer (Proposed), This consortium combines researchers with common interest in understanding cell cycle signaling and regulation with specific focus on two key cancer-related processes (cell cycle control, apoptosis) and/or three specific malignancy types (oesophageal, prostate and haematological).

Member, Colorectal & GI Cancer Research Group (Proposed), Speculative idea to cluster PI's around collaborative study on Upper GI and Colon Cancers.Deliberately wide selection of surgeons, pathologists and academic researchers based on stated interest or publication in fields of oesophageal or colorectal cancer.

Member, PHG Funded PI's and Researchers, All Researchers funded under Cycle 3 PRTLI - Programme for Human Genomics