Dr. Christian Kerskens
Lead Physicist, Trinity Inst. of Neurosciences (TCIN)
Associate Research Lecturer, Clinical Medicine
Publications and Further Research Outputs
Peer-Reviewed Publications
Brooke Tornifoglio, Alan J. Stone, Pattie Mathieu, Emma Fitzpatrick, Christian Kerskens, Caitriona Lally, Measuring Vascular Graft Cellularity Non-Destructively: Merging Magnetic Resonance Imaging and Tissue Engineering, Advanced Materials Technologies, 2023
David López Pérez, Arun L.W. Bokde, Christian Kerskens, Complexity analysis of heartbeat-related signals in Brain MRI time series as a potential biomarker for ageing and cognitive performance, The European Physical Journal - Special Topics, 232, (1), 2023, p123 - 133
Tornifoglio B., Johnston R.D., Stone A.J., Kerskens C., Lally C., Microstructural and mechanical insight into atherosclerotic plaques: an ex vivo DTI study to better assess plaque vulnerability, Biomechanics and Modeling in Mechanobiology, 2023
Christian Kerskens, David López Pérez, Reply to Comment on: `Experimental indications of non-classical brain function" (2022 Journal of Physics Communications 6 105001), Journal of Physics Communications, 7, (3), 2023, p038002
Grandjean J, Desrosiers-Gregoire G, Anckaerts C, Angeles-Valdez D, Ayad F, Barrière DA, Blockx I, Bortel A, Broadwater M, Cardoso BM, Célestine M, Hess A, A consensus protocol for functional connectivity analysis in the rat brain., Nature neuroscience, 2023
Grandjean J, Desrosiers-Gregoire G, Anckaerts C, Angeles-Valdez D, Ayad F, Barrière DA, Blockx I, Bortel A, Broadwater M, Cardoso BM, Célestine M, Hess A, Author Correction: A consensus protocol for functional connectivity analysis in the rat brain., Nature neuroscience, 2023
Kerskens CM, Perez DL, Experimental evidence of non-classical brain functions, 2022
Christian Matthias Kerskens, David López Pérez, Experimental indications of non-classical brain functions, Journal of Physics Communications, 6, (10), 2022, p105001
Tornifoglio B., Stone A.J., Kerskens C., Lally C., Ex Vivo Study Using Diffusion Tensor Imaging to Identify Biomarkers of Atherosclerotic Disease in Human Cadaveric Carotid Arteries, Arteriosclerosis, Thrombosis, and Vascular Biology, 42, (11), 2022, p1398 - 1412, p1398-1412
Alan J. Stone, Brooke Tornifoglio, Robert D. Johnston, Karin Shmueli, Christian Kerskens, Caitríona Lally, Quantitative susceptibility mapping of carotid arterial tissue ex vivo: assessing sensitivity to vessel microstructural composition, Magnetic Resonance in Medicine, 86, 2021, p2512 - 2527
Shahid SS, Johnston RD, Smekens C, Kerskens C, Gaul R, Tornifoglio B, Stone AJ, Lally C, Exploring arterial tissue microstructural organization using non-Gaussian diffusion magnetic resonance schemes., Scientific reports, 2021
Syed Salman Shahid, Christian M. Kerskens, Malcolm Burrows, Alice G.Witney, Elucidating the complex organization of neural micro-domains in the locust Schistocerca gregaria using dMRI, Scientific Reports, 11, (3418), 2021, p1 - 12
Kerskens CM, Are Qualia Reducible, Physical Entities?, 2020
McIntosh A, Mela V, Harty C, Minogue AM, Costello DA, Kerskens C, Lynch MA., Iron accumulation in microglia triggers a cascade of events that leads to altered metabolism and compromised function in APP/PS1 mice., Brain Pathology, 2019, p10.1111/bpa.12704.
Christian Kerskens and David Lopez, Evidence of quantum consciousness in evoked zero-spin echoes, ArXiv e-prints, 2018
Kerskens C, Pérez DL, Experimental evidence of non-classical brain functions, 2017
Syed salman Shahid, Christian Kerskens, Robert Gaul, Caitriona Lally, Quantification of extracellular matrix components in arterial tissue using high-resolution micro diffusion tensor imaging, European Molecular Imaging Meeting, Germany, 5-04-2017, 2017
Francesca Sibilia, Elisabeth Kehoe, Dervla Farrell, Christian Kerskens, Desmond O'Neill, Jonathan McNulty, Paul G. Mullins, Arun L.W. Bokde, AGING-RELATED MICROSTRUCTURAL ALTERATIONS ALONG THE LENGTH OF THE CINGULUM BUNDLE, Alzheimer's & Dementia, 13, (7), 2017, pP1087
Syed Salman Shahid, Robert Gaul, Christian Kerskens, Vittoria Flamini, Caitriona Lally, Quantifying the ultrastructure of carotid artery using high-resolution micro-diffusion tensor imaging - Comparison of intact vs. open cut tissue , Physics in Medicine and Biology, 62, (23), 2017, p8850 - 8868
Gormley, S., Rouine, J., McIntosh, A., Kerskens, C., Harkin, A., Glial fibrillary acidic protein (GFAP) immunoreactivity correlates with cortical perfusion parameters determined by bolus tracking arterial spin labelling (bt-ASL) magnetic resonance (MR) imaging in the Wistar Kyoto rat, Physiology and Behavior, 160, 2016, p66-79
Rahman M.M, Callaghan C.K, Kerskens C.M, Chattarji S, O'Mara S.M, Early hippocampal volume loss as a marker of eventual memory deficits caused by repeated stress, Scientific Reports, 6, 2016, p29127
Rouine J, Kelly ME, Jennings-Murphy C, Duffy P, Gorman I, Gormley S, Kerskens CM, Harkin A, Investigation of the mechanisms mediating MDMA "Ecstasy"-induced increases in cerebro-cortical perfusion determined by btASL MRI., Psychopharmacology, 232, (9), 2015, p1501-1513
Flamini V, Creane A.P, Kerskens C.M, Lally C, Imaging and finite element analysis: A methodology for non-invasive characterization of aortic tissue, Medical Engineering and Physics, 37, (1), 2015, p48 - 54
O'Neill A, D'Souza A, Samson A.C, Carballedo A, Kerskens C, Frodl T, Dysregulation between emotion and theory of mind networks in borderline personality disorder, Psychiatry Research - Neuroimaging, 231, (1), 2015, p25 - 32
S. Gormley, C. Kerskens, A. Harkin, 106. Reduced cortical astroglial cell numbers coupled to reduced cortical cerebral blood perfusion in a genetically predisposed model of depression as assessed by magnetic resonance bolus tracking arterial spin labelling (MR-btASL), Brain, Behavior, and Immunity, 40, 2014, pe31
Rahman MM, Kerskens CM, Chattarji S, O'Mara SM, Chronic immobilization stress occludes in vivo cortical activation in an animal model of panic induced by carbon dioxide inhalation., Frontiers in behavioral neuroscience, 8, 2014, p311
Gigliucci V, Gormley S, Gibney S, Rouine J, Kerskens C, Connor TJ, Harkin A, Characterisation of the antidepressant properties of nitric oxide synthase inhibitors in the olfactory bulcectomised rat model of depression, European Neuropsychopharmacology, 24, (8), 2014, p1349 - 1361
Borase T, Ninjbadgar T, Kapetanakis A, Roche S, O'Connor R, Kerskens C, Heise A, Brougham D.F, Stable aqueous dispersions of glycopeptide-grafted selectably functionalized magnetic nanoparticles, Angewandte Chemie - International Edition, 52, (11), 2013, p3164 - 3167
O'Neill A, D'Souza A, Carballedo A, Joseph S, Kerskens C, Frodl T, Magnetic resonance imaging in patients with borderline personality disorder: a study of volumetric abnormalities., Psychiatry research, 213, (1), 2013, p1-10
Flamini V, Kerskens C, Moerman K, Simms CK and Lally C, Fibre orientation of fresh and frozen porcine aorta determined non-invasively, Medical Engineering and Physics, 35, (6), 2013, 765-776
, Fibre orientation of fresh and frozen porcine aorta determined non-invasively using diffusion tensor imaging, Med Eng Phys, 2013
Rouine, J, Gobbo, OL, Campbell, M, Gigliucci, V, Ogden, I, Smith, KM, Duffy, P, Behan, B, Byrne, D, Kelly, ME, Blau, CW, Kerskens, CM, Harkin, A, MDMA "ecstasy' increases cerebral cortical perfusion determined by bolus-tracking arterial spin labelling (btASL) MRI, BRITISH JOURNAL OF PHARMACOLOGY, 169, (5), 2013, p974-987
J Rouine, O L Gobbo, M Campbell, V Gigliucci, I Ogden, K McHugh Smith, P Duffy, B Behan, D Byrne, M E Kelly, C W Blau, C M Kerskens, A Harkin,
Cowley TR, O'Sullivan J, Blau C, Deighan BF, Jones R, Kerskens C, Richardson JC, Virley D, Upton N, Lynch MA, Rosiglitazone attenuates the age-related changes in astrocytosis and the deficit in LTP., Neurobiology of aging, 33, (1), 2012, p162-75
Blau CW, Cowley TR, O'Sullivan J, Grehan B, Browne TC, Kelly L, Birch A, Murphy N, Kelly ÁM, Kerskens CM, Lynch MA, The age-related deficit in LTP is associated with changes in perfusion and blood-brain barrier permeability., Neurobiology of aging, 33, (5), 2012, p1005.e23-35
Michael E Kelly, Christoph W Blau, Karen M Griffin, Oliviero L Gobbo, James FX Jones and Christian M Kerskens, Quantitative functional magnetic resonance imaging of brain activity using bolus-tracking arterial spin labeling , Journal of Cerebral Blood Flow & Metabolism, 2010
Cowley RT, O'Sullivan J, Blau C; Deighan BF; Jones R; Kerskens C; Richardson JC; Virley D; Upton N; Lynch ML , Rosiglitazone attenuates the age-related changes in astrocytosis and the deficit in LTP, Neurobiology of Aging, 2010
Moerman, KM ; Kerskens, CM ; Lally, C ; Flamini, V ; Simms, CK , Evaluation of a Validation Method for MR Imaging-Based Motion Tracking Using Image Simulation, EURASIP Journal on Advances in Signal Processing, 2010, 2010, p942131
Dunleavy M, Shinoda S, Schindler C, Ewart C, Dolan R, Gobbo OL, Kerskens CM, Henshall DC, Experimental neonatal status epilepticus and the development of temporal lobe epilepsy with unilateral hippocampal sclerosis., The American journal of pathology, 176, (1), 2010, p330-42
Vittoria Flamini, Christian Kerskens, Kevin Mattheus Moerman, Ciaran Simms and Caitríona Lally , Imaging Arterial Fibres Using Diffusion Tensor Imaging-Feasibility Study and Preliminary Results, EURASIP Journal on Advances in Signal Processing, 2010, (904091), 2010
C. M. P. O'Tuathaigh, M. Harte, C. O'Leary, G. J. O'Sullivan, C. Blau, D. Lai, R. P. Harvey, O. Tighe, A. J. Fagan, C. Kerskens, G. Reynolds and J. L. Waddington, Schizophrenia-related endophenotypes in heterozygous neuregulin-1 'knockout' mice , European Journal of Neuroscience, 2010
Griffin KM, Blau CW, Kelly ME, O'Herlihy C, O'Connell PR, Jones JFX, Kerskens CM, Propofol allows precise quantitative arterial spin labelling functional magnetic resonance imaging in the rat, NeuroImage, 51, (4), 2010, p1395-1404
R. E. Gonzalez-Reyes, K. Murphy, R. Bechara, C. Blau, C. Kerskens, M. Lynch, Evidence of an inverse correlation between T2 relaxation time and microglial activation in the cortex of aged rats, Proc Physiol Soc 15, C10, 2009
R. Kelly, C. Blau, E. O'Hanlon, C.G. Connolly, C. Kerskens, M.A. Lynch, OPTIMIZED VOXEL-BASED MORPHOMETRY AND T2 RELAXOMETRY REVEAL SIGNIFICNT AGE-RELATED DECREASES IN AREAS OF THE RAT BRAIN, MRI Satellite Symposium, 2009
C.W. Blau, R.J. Kelly, C.M. Kerskens, M.A. Lynch, AGE-RELATED MAGNETIC RESONANCE RELAXOMETRY CHANGES IN RAT BRAIN CANNOT BE ACCOUNTED FOR BY CHANGES IN GREY MATTER VOLUME AS MEASURED BY VOXEL-BASED MORPHOMETRY (VBM)., MRI Satellite Symposium Presentations, 2009
J.J. Gallagher, R. Kelly, C.M. Kerskens, M.A. Lynch, THE AGE-RELATED DECREASE IN T2 RELAXATION TIME IS NOT EXACERBATED IN MALE APP/PS1 AT 8-9 MONTHS OF AGE., MRI Satellite Symposium, 2009
Kelly, ME, Blau, CW, Kerskens, CM, Bolus-tracking arterial spin labelling: theoretical and experimental results, PHYSICS IN MEDICINE AND BIOLOGY, 54, 2009
J. J. Gallagher, C. M. Kerskens, M. A. Lynch, Spatial learning in middle-aged APP/PS1 mice, but not T2 relaxation time, is associated with amyloid-plaque deposition, Irish Journal of Medical Science, ROYAL ACADEMY OF MEDICINE IN IRELAND, SECTION OF BIOMEDICAL SCIENCES Annual Meeting 2009, 18th-19th June 2009, 178, (Supplement 12), 2009
O. Gobbo, M. Campbell, A.Kiang, P. Kenna, C. Kerskens, G. J. Farrar, P. Humphries, RNAi-MEDIATED REVERSIBLE OPENING OF THE BLOOD-BRAIN AND BLOODRETINA BARRIER, MRI Satellite Symposium, 2009
Christoph W. Blau, Thelma R. Cowley, Joan B. O'Sullivan, Raasay S. Jones, Christian M. Kerskens, Marina A. Lynch, The effect of the PPAR gamma agonist rosiglitazone on age-related changes in grey matter magnetic resonance relaxometry in the rat , Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 5, (4, Supplement), 2009, pp7 - 8
C. W. Blau, K. M. Griffin, O. L. Gobbo, J. F. Jones, and C. M. Kerskens, Fast bolus-tracking fMRI in medetomidine-sedated rats using intravascular tracer: towards quantitative fMRI, International Society for Magnetic Resonance in Medicine, 17th scientific meeting and exhibition, 2009
Blau, CW (Blau, C. W.);Kelly, M; Griffin, KM; Jones, JFX); Kerskens, CM, Fast bolus-tracking function magnetic resonance imaging (fMRI) in medetomidine-sedated rats using intravascular tracer, JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 24th International Symposium on Cerebral Blood Flow and Metabolism/9th International Conference on Quantification of Brain Function with PET, JUN 29-JUL 03, 2009, 29, (S1), NATURE PUBLISHING GROUP, 2009
R. J. Kelly, C. Blau, E. O' Hanlon, C. G. Connolly, C. Kerskens, M. Lynch, Optimized voxel-based morphometry of the rat brain reveals cortical and hippocampal volume decline with age, Proc Physiol Soc 15, PC208 , 2009
J. Rouine, O. Gobbo, C. Kerskens, A. Harkin, Acute and persistent effects of 3,4- methylenedioxymethamphetamine (MDMA; ''ECSTASY'') on magnetic resonance contrast enhanced imaging of perfusion in the rat brain, Irish Journal of Medical Science, ROYAL ACADEMY OF MEDICINE IN IRELAND, SECTION OF BIOMEDICAL SCIENCES Annual Meeting 2009, 18th-19th June 2009, 178, (Supplement 12), 2009
Kelly, M; Blau, C; Gobbo, O; Griffin, K; Jones, J; Kerskens, C , Functional bolus-tracking arterial spin labeling: a new approach to quantitative fMRI, JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 24th International Symposium on Cerebral Blood Flow and Metabolism/9th International Conference on Quantification of Brain Function with PET, JUN 29-JUL 03, 2009, 29, (S1), NATURE PUBLISHING GROUP, 2009
Matthew Campbell, Anh T. H. Nguyen, Anna-Sophia Kiang, Lawrence C. S. Tam, Oliviero L. Gobbo, Christian Kerskens, Sorcha Ni Dhubhghaill, Marian M. Humphries, G.-Jane Farrar, Paul F. Kenna and Peter Humphries, An experimental platform for systemic drug delivery to the retina, Proceedings of the National Academy of Sciences of the United States, 106, (42), 2009, p17817 - 17822
Cooke JM, Kalmykov YP, Coffey WT, and Kerskens, CM, Langevin equation approach to diffusion magnetic resonance imaging, Virtual Journal of Biological Physics Research, 18, (12), 2009
Vittoria Flamini, Christian Kerskens, Caitríona Lally, AN ANISOTROPIC STRUCTURAL MODEL OF THE AORTIC WALL BASED ON TENSILE TESTS AND NON-INVASIVE 3D FIBRE ANALYSIS USING DIFFUSION TENSOR IMAGING, Proceedings of the ASME 2009 Summer Bioengineering Conference (SBC2009), Lake Tahoe, CA, USA, 2009
Cooke JM, Kalmykov YP, Coffey WT, and Kerskens, CM, Langevin equation approach to diffusion magnetic resonance imaging, Physical Review E , 80, (061102), 2009
M.E. Kelly, C.W. Blau, O.L. Gobbo, K.M. Griffin, J.FX. Jones, C.M. Kerskens, QUANTITATIVE FUNCTIONAL MAGNETIC RESONANCE IMAGING WITH BOLUSTRACKING ARTERIAL SPIN LABELLING, MRI Satellite Symposium, 2009
M. E. Kelly, C. W. Blau, R. Bechara, M. A. Lynch, and C. M. Kerskens, Bolus-tracking arterial spin labeling; A new marker for age and age related neurological diseases, International Society for Magnetic Resonance in Medicine, 17th scientific meeting and exhibition, 2009
Campbell, M, Nguyen, ATH, Kiang, AS, Tam, LCS, Gobbo, OL, Kerskens, C, Dhubhghaill, SN, Humphries, MM, Farrar, GJ, Kenna, PF, Humphries, P, An experimental platform for systemic drug delivery to the retina, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106, 2009
Kelly, M; Blau, C; Bechara, R; Lynch, M; Kerskens, C , Bolus-tracking arterial spin labeling: a new marker for aging and age related neurological diseases, JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 24th International Symposium on Cerebral Blood Flow and Metabolism/9th International Conference on Quantification of Brain Function with PET, JUN 29-JUL 03, 2009, 29, (S1), 2009, pp87 - 87
Gallagher, JJ, Tekoriute, R, O'Reilly, JA, Kerskens, C, Gun'ko, YK, Lynch, M, Bimodal magnetic-fluorescent nanostructures for biomedical applications, Journal of Materials Chemistry, 19, 2009, p4081 - 4084
Christoph W. Blau, Thelma R. Cowley, Joan B. O'Sullivan, Raasay S. Jones, Christian M. Kerskens, Marina A. Lynch, The effect of the PPAR gamma agonist rosiglitazone on age-related changes in grey matter magnetic resonance relaxometry in the rat , Alzheimer's & Dementia: The Journal of the Alzheimer's Association , 5, (4, Supplement), 2009, pp207 - 208
M. E. Kelly, C. W. Blau, O. L. Gobbo, K. M. Griffin, J. F. Jones, and C. M. Kerskens, Functional bolus-tracking arterial spin labeling; a new approach to quantitative fMRI , International Society for Magnetic Resonance in Medicine, 17th scientific meeting and exhibition, 2009
Vittoria Flamini, Christian Kerskens, Caitríona Lally, An Anisotropic Structural Model of the Aortic Wall Based on Tensile Tests and Non-Invasive 3D Fibre Analysis Using Diffusion Tensor Imaging, ASME 2009 Summer Bioengineering Conference, Parts A and B, 2009
J. Rouine, B. Behan, M. Kelly, C. Blau, O. Gobbo, C. Kerskens, A. Harkin, PERFUSION MAGNETIC RESONANCE IMAGING USING SPIN LABELLING OF ARTERIAL WATER SHOWS INCREASED CORTICAL BLOOD FLOW FOLLOWING METHYLENEDIOXYMETHAMPHETAMINE (MDMA; "ECSTASY") ADMINISTRATION TO RATS., 2009
Arun Bokde, Michael Ewers, Yetunde Faluyi, Catherine Delaney, Abid Khattack, Ronan Collins, Christian Kerskens, Tara Coughlan, Siobhain Nibrihain, Ian Daly, Greg Swanwick, Desmond O'Neill, Harald Hampel, Alterations in activation between mild cognitive impaired subjects during a working memory task and resting coherent network , Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 5, (4, Supplement), 2009, pp23-
R. Kelly, L. O' Dwyer, E. O' Hanlon, C. Connolly, M. Lynch, and C. Kerskens, An Investigation into Young and Aged Rat Brain Volume Differences by Optimized Voxel-Based Morphometry , International Society for Magnetic Resonance in Medicine, 17th scientific meeting and exhibition, 2009
C. Blau, R. Bechara, C. M. Kerskens, and M. A. Lynch, T2 relaxation time is decreased in hippocampus of aged rats: analysis of the effect of the peroxisome proliferator-activated , International Society for Magnetic Resonance in Medicine, 17th scientific meeting and exhibition, 2009
Campbell M, Kiang AS, Kenna P, Kerskens C, Blau C, O'Dwyer L, Farrar J and Humphries P, Transient blood brain barrier breakage by RNA interference of Claudin-5, Human Molecular Genetics, 2008
Flamini V,Kerskens C, Lally C, Characterization of the 3D Fibre Distribution in a Porcine Aoarta using diffusion tensor imaging, Journal of Biomechanics , European Society of Biomechanics, Lucerne Switzerland, 41, 2008, ppS69-
Campbell, M, Kiang, AS, Kenna, PF, Kerskens, C, Blau, C, O'Dwyer, L, Tivnan, A, Kelly, JA, Brankin, B, Farrar, GJ, Humphries, P, RNAi-mediated reversible opening of the blood-brain barrier, JOURNAL OF GENE MEDICINE, 10, 2008
Brunecker, P, Endres, M, Nolte, CH, Schultze, J, Wegener, S, Jungehulsing, GJ, Muller, B, Kerskens, CM, Fiebach, JB, Villringer, A, Steinbrink, J, Evaluation of an AIF correction algorithm for dynamic susceptibility contrast-enhanced perfusion MR1, MAGNETIC RESONANCE IN MEDICINE, 60, 2008
Cooke J, Kerskens CM, Enhancement of the detection of white matter anisotropy using time-varying diffusion gradients, 25th Annual Meeting of ESMRMB,, Valencia, Spain, October 2-4 2008, 2008
J Gallagher, S. Lalor, R. Tekoriute, Y. Gun'ko, K.H. Mills, C. Kerskens, T2 and T2* measurements of a fluorescent magnetic contrast agent transfected to murine , 25th Annual Meeting of ESMRMB,, Valencia, Spain, October 2-4 2008, 2008
Vittoria Flamini, Christian Kerskens, Caitríona Lally, CHARACTERIZATION OF THE 3D FIBRE DISTRIBUTION IN A PORCINE AORTA USING DIFFUSION TENSOR IMAGING, Journal of Biomechanics, 41, 2008, pS69
Flamini V,Kerskens C, Lally C, Study of the 3D fibre distribution through a Porcine Aorta using diffusion tensor imaging, Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland, Sligo, 2008
Kelly ME, Blau CW, Kerskens CM, Bolus-tracking arterial spin labelling - theoretical and experimental results, 25th Annual Meeting of ESMRMB,, Valencia, Spain, October 2-4 2008, 2008
Corr, SA, Byrne, SJ, Tekoriute, R, Meledandri, CJ, Brougham, DF, Lynch, M, Kerskens, C, O'Dwyer, L, Gun'ko, YK, Linear assemblies of magnetic nanoparticles as MRI contrast agents, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130, 2008
Parkes, LM, Schwarzbach, JV, Bouts, AA, Deckers, RHR, Pullens, P, Kerskens, CM, Norris, DG, Quantifying the spatial resolution of the gradient echo and spin echo BOLD response at 3 Tesla, MAGNETIC RESONANCE IN MEDICINE, 54, 2005
Parkes, LM, Fries, P, Kerskens, CM, Norris, DG, Reduced BOLD response to periodic visual stimulation, NEUROIMAGE, 21, 2004
Parkes LM,Bouts A, Deckers R, Pullens P, Kerskens CM, Norris DG, Schwarzbach JV, Determining the spatial resolution of the gradient echo and, European Society for Magnetic Resonance in Medicine (ESMRMB, 2004
Schmierer, K, Altmann, DR, Kassim, N, Kitzler, H, Kerskens, CM, Doege, CA, Aktas, O, Lunemann, JD, Miller, DH, Zipp, F, Villringer, A, Progressive change in primary progressive multiple sclerosis normal-appearing white matter: a serial diffusion magnetic resonance imaging study, MULTIPLE SCLEROSIS, 10, 2004
Parkes LM, Kerskens CM, Norris DG, The BOLD Signal Amplitude is larger for Aperiodic Stimuli Compared to periodic stimuli, International Society for Magnetic Resonance in Medicine, 11th scientific meeting and exhibition, Toronto, Canada, 2003
Krep, H, Bottiger, BW, Bock, C, Kerskens, CM, Radermacher, B, Fischer, M, Hoehn, M, Hossmann, KA, Time course of circulatory and metabolic recovery of cat brain after cardiac arrest assessed by perfusion- and diffusion-weighted imaging and MR-spectroscopy, RESUSCITATION, 58, 2003
Doege, CA, Kerskens, CM, Romero, BI, Brunecker, P, Junge-Hulsing, J, von Pannwitz, W, Muller, B, Villringer, A, Assessment of diffusion and perfusion deficits in patients with small subcortical ischemia, AMERICAN JOURNAL OF NEURORADIOLOGY, 24, 2003
Parkes LM, Kerskens CM, Norris DG., Characterisation of diffusion-weighted spin echo BOLD signal at 3T, International Society for Magnetic Resonance in Medicine, 11th scientific meeting and exhibition, Toronto, Canada, 2003
Parkes LM, Kerskens CM, Norris DG, Characterisation of diffusion-weighted spin echo BOLD signal at 3T, International Society for Magnetic Resonance in Medicine, 11th scientific meeting and exhibition, Toronto, Canada, 2003
Parkes LM, Kerskens CM, Norris DG, The BOLD Signal Amplitude is larger for Aperiodic Stimuli Compared to periodic stimuli, International Society for Magnetic Resonance in Medicine, 11th scientific meeting and exhibition, 2003
Doege, CA, Tavakolian, R, Kerskens, CM, Romero, BI, Lehmann, R, Einhaupl, KM, Villringer, A, Perfusion and diffusion magnetic resonance imaging in human cerebral venous thrombosis, JOURNAL OF NEUROLOGY, 248, 2001
Brunecker P, Kerskens CM, Endres M, Schultze J, Doege CA, Mueller B, Dirnagl U, Villringer A, High precision measurement of mean transit time for pharmacological MRI, STROKE, 32, (1), 2001, p36
Cerebral blood flow, hemoglobin oxygenation, and water diffusion changes during stroke: fingerprinting with near-infrared spectroscopy and MRI in, Ischemic Blood Flow in the Brain, Tokyo, Springer-Verlag , 2001, [5. Dirnagl U, Obrig H, v. Pannwitz W, Kohl M, Kerskens C, Döge C, Lindauer U, Wolf T, Villringer A]
Kerskens CM, Doege CA, Romero B, Brunecker P, Villringer A, Perfusion and diffusion weighted MRI in human anterior choroidal artery infarction, International Society for Magnetic Resonance in Medicine, 9th scientific meeting and exhibition, Glasgow, Scotland, April 21-27, 2001
Doege, CA, Kerskens, CM, Romero, B, Brunecker, P, von Pannwitz, W, Junge-Hulsing, J, Muller, B, Villringer, A, Diffusion and perfusion imaging in acute diagnostics of cerebral ischaemia, KLINISCHE NEUROPHYSIOLOGIE, 31, 2000
Doege, CA, Kerskens, CM, Romero, BI, Brunecker, P, von Pannwitz, W, Junge-Hulsing, J, Muller, B, Villringer, A, MRI of small human stroke shows reversible diffusion changes in subcortical gray matter, NEUROREPORT, 11, 2000
C. Doege, C. Kerskens, B. Romero, P. Brunecker, W. v. Pannwitz, J. Junge-Hülsing, B. Müller, A. Villringer, Diffusions- und Perfusionsbildgebung in der Akutdiagnostik der zerebralen Ischämie, Klinische Neurophysiologie, 31, (S 1), 2000, pS23--S28
Doege, C.A., Kerskens, C.M., Romero, B., Brunecker, P., Pannwitz, W.V., Junge-Hülsing, J., Müller, B., Villringer, A., Diffusion and perfusion imaging in acute diagnostics of cerebral ischaemia,Diffusions- und Perfusionsbildgebung in der akutdiagnostik der zerebralen ischamie, Klinische Neurophysiologie, 31, (SUPPL. 1), 2000
Busch, E, Kruger, K, Allegrini, PR, Kerskens, CM, Gyngell, ML, Hoehn-Berlage, M, Hossmann, KA, Reperfusion after thrombolytic therapy of embolic stroke in the rat: Magnetic resonance and biochemical imaging, JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 18, 1998
Schmitz, B., Bock, C., Hoehn-Berlage, M., Kerskens, C.M., Bottiger, B.W., Hossman, K.-A., Erratum: Recovery of the rodent brain after cardiac arrest: A functional MRI study (Magnetic Resonance in Medicine (1998) 39 (783-788)), Magnetic Resonance in Medicine, 40, (2), 1998
Kerskens CM, Entwicklung theoretischer und experimenteller Methoden zur Messung der Hirndurchblutung mit Hilfe der Kernspintomographie, Berlin, LogosVerlag, 1998
Bock, C, Schmitz, B, Kerskens, CM, Gyngell, ML, Hossmann, KA, Hoehn-Berlage, M, Functional MRI of somatosensory activation in rat: Effect of hypercapnic up-regulation on perfusion- and BOLD-imaging, MAGNETIC RESONANCE IN MEDICINE, 39, 1998
Kerskens CM, Tavakolian R, Villringer A, A new mathematical description of the NMR signal of Brain perfusion in bolus track: determination of mean transit time in different brain regions in human, International Society for Magnetic Resonance in Medicine, 6th scientific meeting and exhibition, Sydney, April 18-24, 1998, 1998, pp46
Schmitz B, Bock C, Hoehn-Berlage M, Kerskens CM, Bottiger BW, Hossmann KA, Recovery of the rodent brain after cardiac arrest: a functional MRI study, Magnetic Resonance in Medicine, 39, (5), 1998, p783 - 788
Krep H, Böttiger BW, Bock C, Schmitz B, Kerskens CM, Hoehn-Berlage M und Hossmann K-A, Monitoring of brain recovery after cardiac arrest by combined perfusion- and diffusion-weighted imaging and MR-spectroscopy, International Society for Magnetic Resonance in Medicine, 5th scientific meeting and exhibition, Vancouver, April 12-18, 1997, 1997
Busch E, Kerskens CM und Hoehn-Berlage M, Hyper- and hypointense areas observed concurrently on diffusion-weighted images in rats after 1 week of permanent focal cerebral ischemia, International Society for Magnetic Resonance in Medicine, 5th scientific meeting and exhibition, Vancouver, April 12-18, 1997, 1997
Bock C, Busch G, Brinker G, Krep H, Kerskens CM, Hossmann K-A, Hoehn-Berlage M, Simultaneous recordings of f-MRI and evoked cortical potentials during somatosensory stimulation in a alpha-chloralose anesthetized rats, International Society for Magnetic Resonance in Medicine, 5th scientific meeting and exhibition, April 12-18, 1997, 1997
Functional magnetic resonance imaging after cardiac arrest in rat in, editor(s)Krieglstein J and Oberpichler-Schwenk H , Pharmacology of Cerebral Ischemia , Stuttgart, Medpharm Scientific Publishers, 1996, [Hossmann K-A, Schmitz B, Bock C, Kerskens CM, Hoehn-Berlage M]
Allegrini PR, Hoehn-Berlage M, Busch E, Krueger K, Kerskens CM, NMR imaging observation of rat brain perfusion changes during stroke: interpretation based on combination with physiological parameters, International Society for Magnetic Resonance in Medicine, 4th scientific meeting and exhibition, New York, April 27-May 3, 1996
Schmitz B, Bock C, Kerskens CM, Hoehn-Berlage M, Boettiger BW, Hossmann K-A, Recovery of the coupling of cerebral blood flow to neuronal activation following cardiac arrest in rats: a functional MRI study, International Society for Magnetic Resonance in Medicine, 4th scientific meeting and exhibition, April 27-May 3, 1996, 1996
Busch E, Krueger K, Allegrini PR, Kerskens CM, Hoehn-Berlage M, Hossmann K-A, Rt-pa treatment of thromboembolic stroke in rat: assessment by repeated ultrafast arterial spin tagging perfusion., International Society for Magnetic Resonance in Medicine, 4th scientific meeting and exhibition, April 27-May 3, 1996, 1996
Stroke treatment with a new nonselective cation channel blocker extends the therapeutical window: A longitudinal diffusion nmr imaging study in, editor(s)Krieglstein J and Oberpichler-Schwenk H , Pharmacology of Cerebral Ischemia , Stuttgart, Medpharm Scientific Publishers, 1996, [Hoehn-Berlage M, Busch E, Eis M, Schmitz B, Kerskens CM, Uhlenkueken U, Gyngell ML, K-A Hossmann]
Bock C, Schmitz B, Kerskens CM, Gyngell ML, Hoehn-Berlage M, Hossmann K-A, Perfusion- und T2*-weighted imaging of functional activation in rat: Upregulation by transient hypercapnia, International Society for Magnetic Resonance in Medicine, 4th scientific meeting and exhibition, April 27-May 3, 1996, 1996
Hoehn-Berlage M, Eis M, Busch E, Schmitz B, Gyngell ML, Kerskens CM, Hossmann K-A, Stroke therapy with a new non-selective cation channel blocker: diffusion NMR imaging and metabolite mapping, International Society for Magnetic Resonance in Medicine, 4th scientific meeting and exhibition, April 27-May 3, 1996, 1996
Kerskens, CM, HoehnBerlage, M, Schmitz, B, Busch, E, Bock, C, Gyngell, ML, AlexanderHossmann, K, Ultrafast perfusion-weighted MRI of functional brain activation in rats during forepaw stimulation: Comparison with T*(2)-weighted MRI, NMR IN BIOMEDICINE, 9, 1996
Kerskens CM, Hoehn-Berlage M, Schmitz B, Busch E, Bock C, Gyngell ML, Hossmann K-A, Fast perfusion measurement of functional activation of rat brain during forepaw stimulation: comparison with T2*-fMRI, laser-doppler flow measurement and 14C-iodoantipyrine autoradiography, International Society for Magnetic Resonance in Medicine, 4th scientific meeting and exhibition, April 27-May 3, 1996, 1996
Kerskens CM, Hoehn-Berlage M, Schmitz B, Busch E, Bock C, Gyngell ML, Hossmann K-A, Ultrafast perfusion-weighted MRI of functional brain activation in rats during forepaw stimulation: comparison with T2*-weighted MRI, NMR in Biomedicine, 8, 1996, p20-23
Wiedenhover I, Kerskens C, Eschenauer M, Albers S, v. Brentano P, Analogous negative-parity spectra of Xe-125 and Xe-127, Zeitschrift fuer Physik A-Hadrons and Nuclei, 350, (4), 1995, p287 - 288
Wiedenhover I, Neuneyer U, Kerskens C, Altmann J, Stuch O, Theuerkauf J, Siems G, Wirowski R, Eschenauer M, v. Brentano P, Schubart R, Kluge H, Maier KH., High-spin structure in Xe-127 and Xe-125, Zeitschrift fuer Physik A-Hadrons and Nuclei, 347 (1), 1993, p71 - 72
Non-Peer-Reviewed Publications
Flamini V,Kerskens C, Lally C, Study of the 3D fibre distribution through A Porcine Aorta using diffusion tensor imaging, Sir Barnard Crossland symposium, 2008, 2008
Kelly ME, Blau CW, Kerskens CM, Bolus-tracking arterial spin labelling - theoretical and experimental results, 17th Annual NMR Symposium, Sheffield, UK, March 31st 2008, 2008
Blau C, Kelly L, Kerskens C, Lynch M, The age-related increase in microglial activation in rat brain is coupled with a decrease in blood flow as measured by MRI, MNIEST conference, UCD Dublin, march 2008, 2008
Döge C, Kerskens CM, Romero BI, Brunecker P, v. Pannwitz W, Junge-Hülsing J, Müller B, Villringer A, . Infarct evolution differs between gray and white matter: a MRI study, 9th European Stroke Conference, Vienna, Austria, May 24-27, 2000, 2000
Schmitz B, Bock C, Kerskens CM, Hoehn-Berlage M, Boettiger BW, Hossmann K-A, Nicht-invasives Monitoring der funktionellen Erholung des Gehirns nach Herz-Kreislaufstillstand mittels funktioneller NMR-Bildgebung, Wissenschaftliche Arbeitstage der deutschen Gesellschaft der Anaesthesisten, Wuerzburg, Germany, 23. -24. Februar, 1996, 1996
Schmitz B, Bock C, Kerskens CM, Hoehn-Berlage M, Boettiger BW, Hossmann K-A, Funktionelle NMR-Bildgebung zur Untersuchung der Erholung des Gehirns nach Herz-Kreislaufstillstand und Reanimation im Tiermodell, Deutscher Anaesthesiekongreß (DAK), Nuernberg, Germany, 19. - 22. Juni, 1996, 1996
Research Expertise
Description
Non-classical brain mechanisms, Extra vascular transport mechanisms, Quantification of cerebral blood flow, Neurovascular coupling, Physiological noise in the brain, Time series analysis of MRI data,Direct detection of cell activation with NMR, NMR relaxation mechanisms in biological tissue, Intra and extra cellular diffusion, Technical development for living science researchProjects
- Title
- Development of new cerebral perfusion biomarkers
- Funding Agency
- SFI
- Date From
- 09-2011
- Date To
- 09-2015