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Professor Patrick Forde
Patrick Prendergast Professor of Immuno-, Surgery

Biography

Prof. Patrick Forde is Prendergast Professor of Immuno-Oncology at Trinity College Dublin and Consultant Medical Oncologist at St. James Hospital Dublin as well as a professor at Johns Hopkins University. He has led the development of immunotherapy for surgically resectable lung cancer from initial concept to worldwide use, initially exploring the role of single agent anti-PD-1 as neoadjuvant therapy and later as principal investigator of the CheckMate 816 trial which led to the approval internationally of neoadjuvant chemo-immunotherapy for stage II-III lung cancer. Long term follow up from this study showed that just 3 doses of immunotherapy before surgery significantly improved long term survival for patients with lung cancer. He leads several translational efforts to optimize the treatment of lung cancer including the global platform neoadjuvant immunotherapy trial, NeoCOAST-2, exploring novel immunotherapy combinations prior to surgery for lung cancer.

Publications and Further Research Outputs

Peer-Reviewed Publications

Forde PM, Spicer JD, Provencio M, Mitsudomi T, Awad MM, Wang C, Lu S, Felip E, Swanson SJ, Brahmer JR, Kerr K, Taube JM, Ciuleanu TE, Tanaka F, Saylors GB, Chen KN, Ito H, Liberman M, Martin C, Broderick S, Wang L, Cai J, Duong Q, Meadows-Shropshire S, Fiore J, Bhatia S, Girard N;, Overall Survival with Neoadjuvant Nivolumab plus Chemotherapy in Lung Cancer, New England Journal of Medicine, 2025 Journal Article, 2025 DOI

Huang, P., Illei, P.B., Franklin, W., Wu, P.-H., Forde, P.M., Ashrafinia, S., Hu, C., Khan, H., Vadvala, H.V., Shih, I.-M., Battafarano, R.J., Jacobs, M.A., Kong, X., Lewis, J., Yan, R., Chen, Y., Housseau, F., Rahmim, A., Fishman, E.K., Ettinger, D.S., Pienta, K.J., Wirtz, D., Brock, M.V., Lam, S., Gabrielson, E., Lung Cancer Recurrence Risk Prediction through Integrated Deep Learning Evaluation, Cancers, 14, (17), 2022 Journal Article, 2022 DOI

Friedlaender, A., Naidoo, J., Luigi Banna, G., Metro, G., Forde, P., Addeo, A., Corrigendum to "Role and impact of immune checkpoint inhibitors in neoadjuvant treatment for NSCLC" [Cancer Treat. Rev. 104 (2022) 102350] (Cancer Treatment Reviews (2022) 104, (S0305737222000135), (10.1016/j.ctrv.2022.102350)), Cancer Treatment Reviews, 104, 2022 Journal Article, 2022 DOI

Ricciuti, B., Wang, X., Alessi, J.V., Rizvi, H., Mahadevan, N.R., Li, Y.Y., Polio, A., Lindsay, J., Umeton, R., Sinha, R., Vokes, N.I., Recondo, G., Lamberti, G., Lawrence, M., Vaz, V.R., Leonardi, G.C., Plodkowski, A.J., Gupta, H., Cherniack, A.D., Tolstorukov, M.Y., Sharma, B., Felt, K.D., Gainor, J.F., Ravi, A., Getz, G., Schalper, K.A., Henick, B., Forde, P., Anagnostou, V., Jänne, P.A., Van Allen, E.M., Nishino, M., Sholl, L.M., Christiani, D.C., Lin, X., Rodig, S.J., Hellmann, M.D., Awad, M.M., Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers with Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels, JAMA Oncology, 8, (8), 2022, p1160-1168 Journal Article, 2022 DOI

Rosner, S., Forde, P.M., Chemotherapy + PD-1/PD-L1 Blockade Should Be the Preferred Option in the Neoadjuvant Therapy of NSCLC, Journal of Thoracic Oncology, 17, (4), 2022, p503-509 Journal Article, 2022 DOI

Cappelli, L.C., Bingham, C.O., Forde, P.M., Anagnostou, V., Brahmer, J., Lipson, E.J., Mammen, J., Schollenberger, M., Shah, A.A., Darrah, E., Anti-RA33 antibodies are present in a subset of patients with immune checkpoint inhibitor-induced inflammatory arthritis, RMD Open, 8, (2), 2022 Journal Article, 2022 DOI

Valsamo Anagnostou, Blair V. Landon, Jamie E. Medina, Patrick Forde, Victor E. Velculescu, Translating the evolving molecular landscape of tumors to biomarkers of response for cancer immunotherapy, Science Translational Medicine, 2022 Journal Article, 2022 DOI

Guo, M.Z., Murray, J.C., Ghanem, P., Voong, K.R., Hales, R.K., Ettinger, D., Lam, V.K., Hann, C.L., Forde, P.M., Brahmer, J.R., Levy, B.P., Feliciano, J.L., Marrone, K.A., Definitive Chemoradiation and Durvalumab Consolidation for Locally Advanced, Unresectable KRAS-mutated Non-Small Cell Lung Cancer, Clinical Lung Cancer, 23, (7), 2022, p620-629 Journal Article, 2022 DOI

Hsu, M.L., Murray, J.C., Psoter, K.J., Zhang, J., Barasa, D., Brahmer, J.R., Ettinger, D.S., Forde, P.M., Hann, C.L., Lam, V.K., Levy, B., Marrone, K.A., Patel, T., Peterson, V., Sagorsky, S., Turner, M., Anagnostou, V., Naidoo, J., Feliciano, J.L., Clinical Features, Survival, and Burden of Toxicities in Survivors More Than One Year After Lung Cancer Immunotherapy, Oncologist, 27, (11), 2022, p971-981 Journal Article, 2022 DOI

Forde, P.M., Spicer, J., Girard, N., Neoadjuvant Nivolumab plus Chemotherapy in Lung Cancer. Reply, The New England journal of medicine, 387, (6), 2022, p572-573 Journal Article, 2022 DOI

Schad, S.E., Chow, A., Mangarin, L., Pan, H., Zhang, J., Ceglia, N., Caushi, J.X., Malandro, N., Zappasodi, R., Gigoux, M., Hirschhorn, D., Budhu, S., Amisaki, M., Arniella, M., Redmond, D., Chaft, J., Forde, P.M., Gainor, J.F., Hellmann, M.D., Balachandran, V., Shah, S., Smith, K.N., Pardoll, D., Elemento, O., Wolchok, J.D., Merghoub, T., Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions, Journal of Experimental Medicine, 219, (6), 2022 Journal Article, 2022 DOI

Shah, P.P., Franke, J.L., Medikonda, R., Jackson, C.M., Srivastava, S., Choi, J., Forde, P.M., Brahmer, J.R., Ettinger, D.S., Feliciano, J.L., Levy, B.P., Marrone, K.A., Naidoo, J., Redmond, K.J., Kleinberg, L.R., Lim, M., Mutation status and postresection survival of patients with non-small cell lung cancer brain metastasis: implications of biomarker-driven therapy, Journal of Neurosurgery, 136, (1), 2022, p56-66 Journal Article, 2022 DOI

Hong, D.S., Rixe, O., Chiu, V.K., Forde, P.M., Dragovich, T., Lou, Y., Nayak-Kapoor, A., Leidner, R., Atkins, J.N., Collaku, A., Fox, F.E., Marshall, M.A., Olszanski, A.J., Mogamulizumab in Combination with Nivolumab in a Phase I/II Study of Patients with Locally Advanced or Metastatic Solid Tumors, Clinical Cancer Research, 28, (3), 2022, p479-488 Journal Article, 2022 DOI

Liang, W., Cai, K., Cao, Q., Chen, C., Chen, H., Chen, J., Chen, K.-N., Chen, Q., Chu, T., Dong, Y., Fan, J., Fang, W., Fu, J., Fu, X., Gao, S., Ge, D., Geng, G., Geng, Q., He, J., Hu, J., Hu, J., Hu, W.-D., Jiang, F., Jiang, T., Jiao, W., Li, H.-C., Li, Q., Li, S., Li, S., Li, X., Liao, Y.-D., Liu, C., Liu, H., Liu, Y., Lu, Z., Luo, Q., Ma, H., Pan, X., Qiao, G., Ren, S., Shen, W., Song, Y., Sun, D., Wang, G., Wang, J., Wang, M., Wang, Q., Wang, W.-X., Wei, L., Wu, M., Wu, N., Xia, H., Xu, S.-D., Yang, F., Yang, K., Yang, Y., Yu, F., Yu, Z.-T., Yue, D.-S., Zhang, L., Zhang, W., Zhang, Z., Zhao, G., Zhao, J., Zhao, X., Zhou, C., Zhou, Q., Zhu, K., Zhu, Y., Hida, T., Dempke, W.C.M., Rossi, A., de Perrot, M., Ramirez, R.A., Provencio, M., Lee, J.M., Passaro, A., Spaggiari, L., Spicer, J., Girard, N., Forde, P.M., Mok, T.S.K., Cascone, T., He, J., International expert consensus on immunotherapy for early-stage non-small cell lung cancer, Translational Lung Cancer Research, 11, (9), 2022, p1742-1762 Journal Article, 2022 DOI

Govindan, R., Aggarwal, C., Antonia, S.J., Davies, M., Dubinett, S.M., Ferris, A., Forde, P.M., Garon, E.B., Goldberg, S.B., Hassan, R., Hellmann, M.D., Hirsch, F.R., Johnson, M.L., Malik, S., Morgensztern, D., Neal, J.W., Patel, J.D., Rimm, D.L., Sagorsky, S., Schwartz, L.H., Sepesi, B., Herbst, R.S., Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of lung cancer and mesothelioma, Journal for ImmunoTherapy of Cancer, 10, (5), 2022 Journal Article, 2022 DOI

Kok, P.S., Forde, P.M., Hughes, B., Sun, Z., Brown, C., Ramalingam, S., Cook, A., Lesterhuis, W.J., Yip, S., O'Byrne, K., Pavlakis, N., Brahmer, J., Anagnostou, V., Ford, K., Fitzpatrick, K., Bricker, A., Cummins, M.M., Stockler, M., Nowak, A.K., Protocol of DREAM3R: DuRvalumab with chEmotherapy as first-line treAtment in advanced pleural Mesothelioma-a phase 3 randomised trial, BMJ Open, 12, (1), 2022 Journal Article, 2022 DOI

Scott, S.C., Shao, X.M., Niknafs, N., Balan, A., Pereira, G., Marrone, K.A., Lam, V.K., Murray, J.C., Feliciano, J.L., Levy, B.P., Ettinger, D.S., Hann, C.L., Brahmer, J.R., Forde, P.M., Karchin, R., Naidoo, J., Anagnostou, V., Sex-specific differences in immunogenomic features of response to immune checkpoint blockade, Frontiers in Oncology, 12, 2022 Journal Article, 2022 DOI

Rosner, S., Liu, C., Forde, P.M., Hu, C., Association of Pathologic Complete Response and Long-Term Survival Outcomes Among Patients Treated With Neoadjuvant Chemotherapy or Chemoradiotherapy for NSCLC: A Meta-Analysis, JTO Clinical and Research Reports, 3, (9), 2022 Journal Article, 2022 DOI

Friedlaender, A., Naidoo, J., Banna, G.L., Metro, G., Forde, P., Addeo, A., Role and impact of immune checkpoint inhibitors in neoadjuvant treatment for NSCLC, Cancer Treatment Reviews, 104, 2022 Journal Article, 2022 DOI

Forde, P.M., Spicer, J., Lu, S., Provencio, M., Mitsudomi, T., Awad, M.M., Felip, E., Broderick, S.R., Brahmer, J.R., Swanson, S.J., Kerr, K., Wang, C., Ciuleanu, T.-E., Saylors, G.B., Tanaka, F., Ito, H., Chen, K.-N., Liberman, M., Vokes, E.E., Taube, J.M., Dorange, C., Cai, J., Fiore, J., Jarkowski, A., Balli, D., Sausen, M., Pandya, D., Calvet, C.Y., Girard, N., Neoadjuvant Nivolumab plus Chemotherapy in Resectable Lung Cancer, New England Journal of Medicine, 386, (21), 2022, p1973-1985 Journal Article, 2022 DOI

Tarhini, A.A., Eads, J.R., Moore, K.N., Tatard-Leitman, V., Wright, J., Forde, P.M., Ferris, R.L., Neoadjuvant immunotherapy of locoregionally advanced solid tumors, Journal for ImmunoTherapy of Cancer, 10, (8), 2022 Journal Article, 2022 DOI

Liang, K.-L., Tackett, S., Myers, S., Brahmer, J.R., Browner, I.S., Ettinger, D.S., Forde, P.M., Hales, R.K., Hann, C.L., Lam, V.K., Marrone, K.A., Patel, T., Peterson, V., Sagorsky, S., Turner, M., Voong, K.R., Naidoo, J., Feliciano, J.L., An Oncology Urgent Care Clinic for the Management of Immune-Related Adverse Events: A Descriptive Analysis, Current Oncology, 29, (6), 2022, p4342-4353 Journal Article, 2022 DOI

Gerber, D.E., Singh, H., Larkins, E., Ferris, A., Forde, P.M., Selig, W., Basu Roy, U., A New Approach to Simplifying and Harmonizing Cancer Clinical Trials - Standardizing Eligibility Criteria, JAMA Oncology, 8, (9), 2022, p1333-1339 Journal Article, 2022 DOI

A. S. Mansfield, Z. Wei, R. Mehra, A. T. Shaw, C. H. Lieu, P. M. Forde, A. E. Drilon, E. P. Mitchell, J. J. Wright, N. Takebe, E. Sharon, D. Hovelson, S. Tomlins, J. Zeng, K. Poorman, N. Malik, R. J. Gray, S. Li, L. M. McShane, L. V. Rubinstein, D. Patton, P. M. Williams, S. R. Hamilton, B. A. Conley, C. L. Arteaga, L. N. Harris, P. J. O"Dwyer, A. P. Chen, K. T. Flaherty, Crizotinib in patients with tumors harboring ALK or ROS1 rearrangements in the NCI-MATCH trial, npj Precision Oncology, 2022 Journal Article, 2022 DOI

Shaikh, F.Y., Gills, J.J., Mohammad, F., White, J.R., Stevens, C.M., Ding, H., Fu, J., Tam, A., Blosser, R.L., Domingue, J.C., Larman, T.C., Chaft, J.E., Spicer, J.D., Reuss, J.E., Naidoo, J., Forde, P.M., Ganguly, S., Housseau, F., Pardoll, D.M., Sears, C.L., Murine fecal microbiota transfer models selectively colonize human microbes and reveal transcriptional programs associated with response to neoadjuvant checkpoint inhibitors, Cancer Immunology, Immunotherapy, 71, (10), 2022, p2405-2420 Journal Article, 2022 DOI

Gridelli, C., Peters, S., Mok, T., Forde, P.M., Reck, M., Attili, I., de Marinis, F., First-line immunotherapy in advanced non-small-cell lung cancer patients with ECOG performance status 2: results of an International Expert Panel Meeting by the Italian Association of Thoracic Oncology, ESMO Open, 7, (1), 2022 Journal Article, 2022 DOI

Chaft, J.E., Shyr, Y., Sepesi, B., Forde, P.M., Preoperative and Postoperative Systemic Therapy for Operable Non"Small-Cell Lung Cancer, Journal of Clinical Oncology, 40, (6), 2022, p546-555 Journal Article, 2022 DOI

Hwang, M., Canzoniero, J.V., Rosner, S., Zhang, G., White, J.R., Belcaid, Z., Cherry, C., Balan, A., Pereira, G., Curry, A., Niknafs, N., Zhang, J., Smith, K.N., Sivapalan, L., Chaft, J.E., Reuss, J.E., Marrone, K., Murray, J.C., Li, Q.K., Lam, V., Levy, B.P., Hann, C., Velculescu, V.E., Brahmer, J.R., Forde, P.M., Seiwert, T., Anagnostou, V., Peripheral blood immune cell dynamics reflect antitumor immune responses and predict clinical response to immunotherapy, Journal for ImmunoTherapy of Cancer, 10, (6), 2022 Journal Article, 2022 DOI

Mansfield, A.S., Brown, R.J., Sammon, C., Daumont, M.J., McKenna, M., Sanzari, J.K., Forde, P.M., The Predictive and Prognostic Nature of Programmed Death-Ligand 1 in Malignant Pleural Mesothelioma: A Systematic Literature Review, JTO Clinical and Research Reports, 3, (5), 2022 Journal Article, 2022 DOI

Patrick M. Forde, Valsamo Anagnostou, Zhuoxin Sun, Suzanne E. Dahlberg, Hedy L. Kindler, Noushin Niknafs, Thomas Purcell, Rafael Santana-Davila, Arkadiusz Z. Dudek, Hossein Borghaei, Mara Lanis, Zineb Belcaid, Kellie N. Smith, Archana Balan, James R. White, Christopher Cherry, I. K. Ashok Sivakumar, Xiaoshan M. Shao, Hok Yee Chan, Dipika Singh, Sampriti Thapa, Peter B. Illei, Drew M. Pardoll, Rachel Karchin, Victor E. Velculescu, Julie R. Brahmer, Suresh S. Ramalingam, Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and immunologic analyses from the phase 2 PrE0505 trial, Nature Medicine, 27, (11), 2021, p1910--1920 Journal Article, 2021 DOI

Chen, X., Sheikh, K., Nakajima, E., Lin, C.T., Lee, J., Hu, C., Hales, R.K., Forde, P.M., Naidoo, J., Voong, K.R., Radiation Versus Immune Checkpoint Inhibitor Associated Pneumonitis: Distinct Radiologic Morphologies, Oncologist, 26, (10), 2021, pe1822-e1832 Journal Article, 2021 DOI

Reuss, J.E., Brigham, E., Psoter, K.J., Voong, K.R., Shankar, B., Ettinger, D.S., Marrone, K.A., Hann, C.L., Levy, B., Feliciano, J.L., Brahmer, J.R., Feller-Kopman, D., Lerner, A.D., Lee, H., Yarmus, L., Hales, R.K., D'Alessio, F., Danoff, S.K., Forde, P.M., Suresh, K., Naidoo, J., Pretreatment Lung Function and Checkpoint Inhibitor Pneumonitis in NSCLC, JTO Clinical and Research Reports, 2, (10), 2021 Journal Article, 2021 DOI

Curigliano, G., Gelderblom, H., Mach, N., Doi, T., Tai, D., Forde, P.M., Sarantopoulos, J., Bedard, P.L., Lin, C.-C., Stephen Hodi, F., Wilgenhof, S., Santoro, A., Sabatos-Peyton, C.A., Longmire, T.A., Xyrafas, A., Sun, H., Gutzwiller, S., Manenti, L., Naing, A., Phase I/Ib clinical trial of sabatolimab, an anti"TIM-3 antibody, alone and in combination with spartalizumab, an anti"PD-1 antibody, in advanced solid tumors, Clinical Cancer Research, 27, (13), 2021, p3620-3629 Journal Article, 2021 DOI

Mathios, D., Johansen, J.S., Cristiano, S., Medina, J.E., Phallen, J., Larsen, K.R., Bruhm, D.C., Niknafs, N., Ferreira, L., Adleff, V., Chiao, J.Y., Leal, A., Noe, M., White, J.R., Arun, A.S., Hruban, C., Annapragada, A.V., Jensen, S.Ø., Ørntoft, M.-B.W., Madsen, A.H., Carvalho, B., de Wit, M., Carey, J., Dracopoli, N.C., Maddala, T., Fang, K.C., Hartman, A.-R., Forde, P.M., Anagnostou, V., Brahmer, J.R., Fijneman, R.J.A., Nielsen, H.J., Meijer, G.A., Andersen, C.L., Mellemgaard, A., Bojesen, S.E., Scharpf, R.B., Velculescu, V.E., Detection and characterization of lung cancer using cell-free DNA fragmentomes, Nature Communications, 12, (1), 2021 Journal Article, 2021 DOI

Friedes, C., Chakrabarti, T., Olson, S., Prichett, L., Brahmer, J.R., Forde, P.J., Voong, R.K., Marrone, K.A., Lam, V.K., Hann, C.L., Broderick, S.R., Battafarano, R.J., Ha, J.S., Bush, E.L., Yang, S.C., Hales, R.K., Feliciano, J.L., Association of severe lymphopenia and disease progression in unresectable locally advanced non-small cell lung cancer treated with definitive chemoradiation and immunotherapy, Lung Cancer, 154, 2021, p36-43 Journal Article, 2021 DOI

Caushi, J.X., Zhang, J., Ji, Z., Vaghasia, A., Zhang, B., Hsiue, E.H.-C., Mog, B.J., Hou, W., Justesen, S., Blosser, R., Tam, A., Anagnostou, V., Cottrell, T.R., Guo, H., Chan, H.Y., Singh, D., Thapa, S., Dykema, A.G., Burman, P., Choudhury, B., Aparicio, L., Cheung, L.S., Lanis, M., Belcaid, Z., El Asmar, M., Illei, P.B., Wang, R., Meyers, J., Schuebel, K., Gupta, A., Skaist, A., Wheelan, S., Naidoo, J., Marrone, K.A., Brock, M., Ha, J., Bush, E.L., Park, B.J., Bott, M., Jones, D.R., Reuss, J.E., Velculescu, V.E., Chaft, J.E., Kinzler, K.W., Zhou, S., Vogelstein, B., Taube, J.M., Hellmann, M.D., Brahmer, J.R., Merghoub, T., Forde, P.M., Yegnasubramanian, S., Ji, H., Pardoll, D.M., Smith, K.N., Author Correction: Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers (Nature, (2021), 596, 7870, (126-132), 10.1038/s41586-021-03752-4), Nature, 598, (7881), 2021, pE1 Journal Article, 2021 DOI

Balaji, A., Hsu, M., Lin, C.T., Feliciano, J., Marrone, K., Brahmer, J.R., Forde, P.M., Hann, C., Zheng, L., Lee, V., Illei, P.B., Danoff, S.K., Suresh, K., Naidoo, J., Steroid-refractory PD-(L)1 pneumonitis: Incidence, clinical features, treatment, and outcomes, Journal for ImmunoTherapy of Cancer, 9, (1), 2021 Journal Article, 2021 DOI

Kumar, D., Mishra, A., Lisok, A., Kureshi, R., Shelake, S., Plyku, D., Sen, R., Doucet, M., De Silva, R.A., Mease, R.C., Forde, P.M., Jaffee, E.M., Desai, P., Ganguly, S., Gabrielson, E., Vaidya, D., Spangler, J.B., Nimmagadda, S., Pharmacodynamic measures within tumors expose differential activity of PD(L)-1 antibody therapeutics, Proceedings of the National Academy of Sciences of the United States of America, 118, (37), 2021 Journal Article, 2021 DOI

Anagnostou, V., Niknafs, N., Marrone, K., Bruhm, D.C., White, J.R., Naidoo, J., Hummelink, K., Monkhorst, K., Lalezari, F., Lanis, M., Rosner, S., Reuss, J.E., Smith, K.N., Adleff, V., Rodgers, K., Belcaid, Z., Rhymee, L., Levy, B., Feliciano, J., Hann, C.L., Ettinger, D.S., Georgiades, C., Verde, F., Illei, P., Li, Q.K., Baras, A.S., Gabrielson, E., Brock, M.V., Karchin, R., Pardoll, D.M., Baylin, S.B., Brahmer, J.R., Scharpf, R.B., Forde, P.M., Velculescu, V.E., Multimodal genomic features predict outcome of immune checkpoint blockade in non-small-cell lung cancer, Nature cancer, 1, (1), 2020, p99-111 Journal Article, 2020 DOI

Naidoo, J., Reuss, J.E., Suresh, K., Feller-Kopman, D., Forde, P.M., Mehta Steinke, S., Rock, C., Johnson, D.B., Nishino, M., Brahmer, J.R., Immune-related (IR)-pneumonitis during the COVID-19 pandemic: Multidisciplinary recommendations for diagnosis and management, Journal for ImmunoTherapy of Cancer, 8, (1), 2020 Journal Article, 2020 DOI

Naing, A., Gainor, J.F., Gelderblom, H., Forde, P.M., Butler, M.O., Lin, C.-C., Sharma, S., Ochoa De Olza, M., Varga, A., Taylor, M., Schellens, J.H.M., Wu, H., Sun, H., Silva, A.P., Faris, J., Mataraza, J., Cameron, S., Bauer, T.M., A first-in-human phase 1 dose escalation study of spartalizumab (PDR001), an anti-PD-1 antibody, in patients with advanced solid tumors, Journal for ImmunoTherapy of Cancer, 8, (1), 2020 Journal Article, 2020 DOI

Linehan, A., Forde, P.M., Moving Immunotherapy into Early-Stage Lung Cancer, Cancer Journal (United States), 26, (6), 2020, p543-547 Journal Article, 2020 DOI

Shankar, B., Zhang, J., Naqash, A.R., Forde, P.M., Feliciano, J.L., Marrone, K.A., Ettinger, D.S., Hann, C.L., Brahmer, J.R., Ricciuti, B., Owen, D., Toi, Y., Walker, P., Otterson, G.A., Patel, S.H., Sugawara, S., Naidoo, J., Multisystem Immune-Related Adverse Events Associated with Immune Checkpoint Inhibitors for Treatment of Non-Small Cell Lung Cancer, JAMA Oncology, 6, (12), 2020, p1952-1956 Journal Article, 2020 DOI

Friedes, C., Mai, N., Fu, W., Hu, C., Hazell, S.Z., Han, P., McNutt, T.R., Forde, P.M., Redmond, K.J., Voong, K.R., Hales, R.K., Isolated progression of metastatic lung cancer: Clinical outcomes associated with definitive radiotherapy, Cancer, 126, (20), 2020, p4572-4583 Journal Article, 2020 DOI

Lam, V.K., Forde, P.M., Another Brick in the Wall: Sintilimab Plus Chemotherapy in Advanced Lung Cancer, Journal of Thoracic Oncology, 15, (10), 2020, p1556-1558 Journal Article, 2020 DOI

Naidoo, J., Cottrell, T.R., Lipson, E.J., Forde, P.M., Illei, P.B., Yarmus, L.B., Voong, K.R., Feller-Kopman, D., Lee, H., Riemer, J., Wang, D., Taube, J.M., Brahmer, J.R., Lin, C.T., Danoff, S.K., D'Alessio, F.R., Suresh, K., Chronic immune checkpoint inhibitor pneumonitis, Journal for ImmunoTherapy of Cancer, 8, (1), 2020 Journal Article, 2020 DOI

Reuss, J.E., Forde, P.M., Immunotherapy for mesothelioma: Rationale and new approaches, Clinical Advances in Hematology and Oncology, 18, (9), 2020, p562-572 Journal Article, 2020

Reuss, J.E., Anagnostou, V., Cottrell, T.R., Smith, K.N., Verde, F., Zahurak, M., Lanis, M., Murray, J.C., Chan, H.Y., McCarthy, C., Wang, D., White, J.R., Yang, S., Battafarano, R., Broderick, S., Bush, E., Brock, M., Ha, J., Jones, D., Merghoub, T., Taube, J., Velculescu, V.E., Rosner, G., Illei, P., Pardoll, D.M., Topalian, S., Naidoo, J., Levy, B., Hellmann, M.D., Brahmer, J.R., Chaft, J.E., Forde, P.M., Neoadjuvant nivolumab plus ipilimumab in resectable non-small cell lung cancer, Journal for ImmunoTherapy of Cancer, 8, (2), 2020 Journal Article, 2020 DOI

Forde, P.M., Scherpereel, A., Tsao, A.S., Use of Immune Checkpoint Inhibitors in Mesothelioma, Current Treatment Options in Oncology, 20, (2), 2019 Journal Article, 2019 DOI

Danilova, L., Anagnostou, V., Caushi, J.X., Sidhom, J.-W., Guo, H., Chan, H.Y., Suri, P., Tam, A., Zhang, J., Asmar, M.E., Marrone, K.A., Naidoo, J., Brahmer, J.R., Forde, P.M., Baras, A.S., Cope, L., Velculescu, V.E., Pardoll, D.M., Housseau, F., Smith, K.N., The mutation-associated neoantigen functional expansion of specific T cells (MANAFEST) assay: A sensitive platform for monitoring antitumor immunity, Cancer Immunology Research, 6, (8), 2018, p888-899 Journal Article, 2018 DOI

Marrone, K.A., Zhou, X., Forde, P.M., Purtell, M., Brahmer, J.R., Hann, C.L., Kelly, R.J., Coleman, B., Gabrielson, E., Rosner, G.L., Ettinger, D.S., A Randomized Phase II Study of Metformin plus Paclitaxel/Carboplatin/Bevacizumab in Patients with Chemotherapy-Naïve Advanced or Metastatic Nonsquamous Non-Small Cell Lung Cancer, Oncologist, 23, (7), 2018, p859-865 Journal Article, 2018 DOI

Marrone, K.A., Forde, P.M., Cancer immunotherapy in older patients, Cancer Journal (United States), 23, (4), 2017, p219-222 Journal Article, 2017 DOI

Baik, C.S., Rubin, E.H., Forde, P.M., Mehnert, J.M., Collyar, D., Butler, M.O., Dixon, E.L., Chow, L.Q.M., Immuno-oncology clinical trial design: Limitations, challenges, and opportunities, Clinical Cancer Research, 23, (17), 2017, p4992-5002 Journal Article, 2017 DOI

Naidoo, J., Cappelli, L.C., Forde, P.M., Marrone, K.A., Lipson, E.J., Hammers, H.J., Sharfman, W.H., Le, D.T., Baer, A.N., Shah, A.A., Albayda, J., Manno, R.L., Haque, U., Gutierrez, A.K., Bingham, C.O., Brahmer, J.R., Inflammatory arthritis: A newly recognized adverse event of immune checkpoint blockade, Oncologist, 22, (6), 2017, p627-630 Journal Article, 2017 DOI

Anagnostou, V., Yarchoan, M., Hansen, A.R., Wang, H., Verde, F., Sharon, E., Collyar, D., Chow, L.Q.M., Forde, P.M., Immuno-oncology trial endpoints: Capturing clinically meaningful activity, Clinical Cancer Research, 23, (17), 2017, p4959-4969 Journal Article, 2017 DOI

Illei, P.B., Belchis, D., Tseng, L.-H., Nguyen, D., De Marchi, F., Haley, L., Riel, S., Beierl, K., Zheng, G., Brahmer, J.R., Askin, F.B., Gocke, C.D., Eshleman, J.R., Forde, P.M., Lin, M.-T., Clinical mutational profiling of 1006 lung cancers by next generation sequencing, Oncotarget, 8, (57), 2017, p96684-96696 Journal Article, 2017 DOI

Anagnostou, V., Smith, K.N., Forde, P.M., Niknafs, N., Bhattacharya, R., White, J., Zhang, T., Adleff, V., Phallen, J., Wali, N., Hruban, C., Guthrie, V.B., Rodgers, K., Naidoo, J., Kang, H., Sharfman, W., Georgiades, C., Verde, F., Illei, P., Li, Q.K., Gabrielson, E., Brock, M.V., Zahnow, C.A., Baylin, S.B., Scharpf, R.B., Brahmer, J.R., Karchin, R., Pardoll, D.M., Velculescu, V.E., Evolution of neoantigen landscape during immune checkpoint blockade in non-small cell lung cancer, Cancer Discovery, 7, (3), 2017, p264-276 Journal Article, 2017 DOI

Zeidan, A., Faltas, B., Forde, P., Subhawong, A., Bello, C., Bolaños-Meade, J., Sequential occurrence of a splenic marginal zone lymphoma, extranodal MALT lymphoma, and hodgkin lymphoma, Clinical Lymphoma, Myeloma and Leukemia, 13, (4), 2013, p496-498 Journal Article, 2013 DOI

Zeidan, A.M., Forde, P.M., Streiff, M.B., Diagnosis, Treatment, and Prevention of Cancer-Associated Venous Thromboembolism, Abeloff's Clinical Oncology: Fifth Edition, 2013, p542-561 Book Chapter, 2013

Forde, P.M., Ettinger, D.S., Targeted therapy for non-small-cell lung cancer: Past, present and future, Expert Review of Anticancer Therapy, 13, (6), 2013, p745-758 Journal Article, 2013 DOI

Boikos, S.A., Forde, P.M., Chatterjee, S., Hann, C.L., Tumor lysis syndrome in limited-stage small-cell lung cancer, Journal of Thoracic Oncology, 8, (7), 2013 Journal Article, 2013 DOI

Forde, P.M., Kelly, R.J., Genomic alterations in advanced esophageal cancer may lead to subtype-specific therapies, Oncologist, 18, (7), 2013, p823-832 Journal Article, 2013 DOI

Forde, P.M., Reiss, K.A., Zeidan, A.M., Brahmer, J.R., What lies within: Novel strategies in immunotherapy for non-small cell lung cancer, Oncologist, 18, (11), 2013, p1203-1213 Journal Article, 2013 DOI

Forde, P.M., Kelly, R.J., Chemotherapeutic and targeted strategies for locally advanced and metastatic esophageal cancer, Journal of Thoracic Oncology, 8, (6), 2013, p673-684 Journal Article, 2013 DOI

Forde, PM, Rock, K, Wilson, G, O'Byrne, KJ, Ipilimumab-induced Immune-related Renal Failure - A Case Report, ANTICANCER RESEARCH, 32, (10), 2012, p4607-4608 Journal Article, 2012

Forde, P.M., Rudin, C.M., Crizotinib in the treatment of non-small-cell lung cancer, Expert Opinion on Pharmacotherapy, 13, (8), 2012, p1195-1201 Journal Article, 2012 DOI

Lefter, S., Forde, P., Nashat, H., Moylan, E., Yacoob, Y., A 27-year-old man with diplopia, fatiguable ptosis and rash: A rare presentation of angiocentric T cell lymphoma with lymphomatoid vasculitis, BMJ Case Reports, 2011 Journal Article, 2011 DOI

Forde, P., Murphy, C., O'Sullivan, C., Carney, D., Triad of trichomegaly, alopecia and male-pattern hair growth during treatment with erlotinib in non-small-cell lung cancer, Irish Journal of Medical Science, 180, (1), 2011, p283-284 Journal Article, 2011 DOI

Rock, C., Brady, D., Forde, P., Lucey, P., Horgan, M., Leptospirosis: a globally increasing zoonotic disease., BMJ case reports, 2010, 2010 Journal Article, 2010 DOI

Recognition

Awards and Honours

ECOG-ACRIN Young Investigator Award 2023

Daniel C. Ihde Award for Medical Oncology, International Association for the Study of Lung Cancer 2022

Memberships

Member of European Society of Medical Oncology, American Association for Cancer Research, American Society of Clinical Oncology