Professor Seamas Donnelly
Professor of Medicine, Discipline Head, Clinical Medicine
Publications and Further Research Outputs
Peer-Reviewed Publications
Donnelly S.C., Coronavirus disease 2019-lessons learnt, QJM, 115, (3), 2022, p129-
Donnelly S.C., COVID-19 vaccine hesitancy after side effects to the first vaccine: What are our options?, QJM, 115, (5), 2022, p267-
Donnelly S.C., Why do vaccinated people get re-infected with COVID-19 infection?, QJM, 115, (2), 2022, p65-
Kelly M.J., Breathnach C., Tracey K.J., Donnelly S.C., Manipulation of the inflammatory reflex as a therapeutic strategy, Cell Reports Medicine, 3, (7), 2022
Donnelly S.C., Long-COVID syndrome and the lung, QJM, 115, (6), 2022, p347-
Donnelly S.C., After acute there is the long-COVID syndrome: What's the plan?, QJM, 115, (1), 2022, p1 - 2, p1-2
Mitchell PD, Olaniyi J, Buckley C, Donnelly SC., Long COVID syndrome and the lung-How long will it last?, QJM : monthly journal of the Association of Physicians, 2022
Donnelly S.C., Association of Physicians of Great Britain and Ireland (www.aopgbi.org)-why not become a member?, QJM, 115, (4), 2022, p199-
Ralph Panstruga, Seamas C. Donnelly, Jürgen Bernhagen, A cross"kingdom view on the immunomodulatory role of MIF / D"DT proteins in mammalian and plant Pseudomonas infections, Immunology, 2022
Thiele M., Donnelly S.C., Mitchell R.A., OxMIF: a druggable isoform of macrophage migration inhibitory factor in cancer and inflammatory diseases, Journal for ImmunoTherapy of Cancer, 10, (9), 2022
Donnelly S.C., Community-Acquired pneumonia and non-invasive ventilation-a valid ICU avoidance strategy?, QJM, 115, (7), 2022, p427-
McElroy AN, Invernizzi R, Laskowska JW, O'Neill A, Doroudian M, Moghoofei M, Mostafaei S, Li F, Przybylski AA, O'Dwyer DN, Bowie AG, Fallon PG, Maher TM, Hogaboam CM, Molyneaux PL, Hirani N, Armstrong ME, Donnelly SC., Candidate Role for Toll-like Receptor 3 L412F Polymorphism and Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis., American journal of respiratory and critical care medicine, 2022
Mitchell P.D., Buckley C., Subramaniam A., Crowther S., Donnelly S.C., Elevated serum ACE levels in patients with post-acute COVID-19 syndrome, QJM : monthly journal of the Association of Physicians, 115, (10), 2022, p651 - 652, p651-652
Anne Trappe, Seamas C Donnelly, Paul McNally, Judith A Coppinger, Role of extracellular vesicles in chronic lung disease, Thorax, 76, (10), 2021, p1047--1056
Mohammad Doroudian, Ronan MacLoughlin, Fergus Poynton, Adriele Prina-Mello, Seamas C Donnelly, Nanotechnology based therapeutics for lung disease, Thorax, 74, (10), 2019, p965--976
Fischer A, Strek ME, Cottin V, Dellaripa PF, Bernstein EJ, Brown KK, Danoff SK, Distler O, Hirani N, Jones KD, Khanna D, Lee JS, Lynch DA, Maher TM, Donnelly SC, Proceedings of the American College of Rheumatology/Association of Physicians of Great Britain and Ireland Connective Tissue Disease-Associated Interstitial Lung Disease Summit: A Multidisciplinary Approach to Address Challenges and Opportunities., QJM : monthly journal of the Association of Physicians, 2019
Gray RD, Hardisty G, Regan KH, Smith M, Robb CT, Duffin R, Mackellar A, Felton JM, Paemka L, McCullagh BN, Lucas CD, Dorward DA, McKone EF, Cooke G, Donnelly SC, Singh PK, Stoltz DA, Haslett C, McCray PB, Whyte MKB, Rossi AG, Davidson DJ., Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis., Thorax, 73, (2), 2018, p134-144
Grainger JT, Maeda Y, Donnelly SC, Vaizey CJ, Assessment and management of patients with intestinal failure: a multidisciplinary approach., Clinical and experimental gastroenterology, 2018
Smyth H, Flood R, Kane D, Donnelly S, Mullan RH, Shrinking lung syndrome and systemic lupus erythematosus: a case series and literature review., QJM : monthly journal of the Association of Physicians, 2018
Mostafaei S, Kazemnejad A, Azimzadeh Jamalkandi S, Amirhashchi S, Donnelly SC, Armstrong ME, Doroudian M, Identification of Novel Genes in Human Airway Epithelial Cells associated with Chronic Obstructive Pulmonary Disease (COPD) using Machine-Based Learning Algorithms., Scientific reports, 2018
Donnelly SC, Breakfast-the most important meal of the day!!, QJM : monthly journal of the Association of Physicians, 2018
Donnelly SC, 18F-FDG-PET/CT scanning-clinical usefulness beyond cancer., QJM : monthly journal of the Association of Physicians, 2018
Schupp JC, Freitag-Wolf S, Bargagli E, Mihailovi"-Vu"ini" V, Rottoli P, Grubanovic A, Müller A, Jochens A, Tittmann L, Schnerch J, Olivieri C, Fischer A, Jovanovic D, Filipovic S, Videnovic-Ivanovic J, Bresser P, Jonkers R, O'Reilly K, Ho LP, Gaede KI, Zabel P, Dubaniewicz A, Marshall B, Kieszko R, Milanowski J, Günther A, Weihrich A, Petrek M, Kolek V, Keane MP, O'Beirne S, Donnelly S, Haraldsdottir SO, Jorundsdottir KB, Costabel U, Bonella F, Wallaert B, Grah C, Peroš-Golubi"i" T, Luisetti M, Kadija Z, Pabst S, Grohé C, Strausz J, Vašáková M, Sterclova M, Millar A, Homolka J, Slováková A, Kendrick Y, Crawshaw A, Wuyts W, Spencer L, Pfeifer M, Valeyre D, Poletti V, Wirtz H, Prasse A, Schreiber S, Krawczak M, Müller-Quernheim J., Phenotypes of organ involvement in sarcoidosis., The European respiratory journal, 51, (1), 2018
Fischer, A., Donnelly, S.C., Pulmonary fibrosis in connective tissue disease (CTD): Urgent challenges and opportunities, QJM, 110, (8), 2017, p475-476
Cooke G, Kamal I, Strengert M, Hams E, Mawhinney L, Tynan A, O' Reilly C, O' Dwyer DN, Kunkel SL, Knaus UG, Shields DC, Moller DR, Bowie AG, Fallon PG, Hogaboam CM, Armstrong ME, Donnelly SC., Title: Toll-like receptor 3 L412F polymorphism promotes a persistent clinical phenotype in pulmonary sarcoidosis., QJM : monthly journal of the Association of Physicians, 2017
Donnelly, S.C., How do doctors define death?, QJM, 110, (3), 2017, p119-119
O"Beirne, S.L., O"Dwyer, D.N., Walsh, S.M., Dodd, J.D., Crotty, T.B., Donnelly, S.C., The lady with the dragon tattoo, Irish Journal of Medical Science, 186, (1), 2017, p157-160
Donnelly SC, After the Fukushima nuclear disaster of 2011-is Japan better prepared-perhaps not., QJM : monthly journal of the Association of Physicians, 2017
Tynan A, Mawhinney L, Armstrong ME, O'Reilly C, Kennedy S, Caraher E, Jülicher K, O'Dwyer D, Maher L, Schaffer K, Fabre A, McKone EF, Leng L, Bucala R, Bernhagen J, Cooke G, Donnelly SC., Macrophage migration inhibitory factor enhances Pseudomonas aeruginosa biofilm formation, potentially contributing to cystic fibrosis pathogenesis., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31, (11), 2017, p5102-5110
Chong Sy Giin, Herron Malcolm, Dorman Anthony, Little Mark, Donnelly Seamas C, Keane Joseph, McLaughlin Anne Marie, Renal amyloidosis complicating multidrug-resistant tuberculosis , The International Journal of Tuberculosis and Lung Disease , 21 , (4 ), 2017, p476 - 477
Donnelly, S.C., Acromegaly-the importance of early diagnosis, QJM, 110, (7), 2017
Donnelly, S.C., Redefining health for the 21st century: Investing in well-being-the proper meaning of 'health-care', QJM, 110, (4), 2017
Donnelly, S.C., Redefining Health for the 21st. Century-Investing in well-being-the proper meaning of "health-care", QJM, 110, (5), 2017
Donnelly, S.C., Why is the United States a sick country?, QJM, 110, (2), 2017, p57-58
Donnelly, S.C., Building a culture of health in society, QJM, 110, (6), 2017
Hisert, K.B., Heltshe, S.L., Pope, C., Jorth, P., Wu, X., Edwards, R.M., Radey, M., Accurso, F.J., Wolter, D.J., Cooke, G., Adam, R.J., Carter, S., Grogan, B., Launspach, J.L., Donnelly, S.C., Gallagher, C.G., Bruce, J.E., Stoltz, D.A., Welsh, M.J., Hoffman, L.R., McKone, E.F., Singh, P.K., Restoring cystic fibrosis transmembrane conductance regulator function reduces airway bacteria and inflammation in people with cystic fibrosis and chronic lung infections, American Journal of Respiratory and Critical Care Medicine, 195, (12), 2017, p1617-1628
Donnelly, S.C., Fog in the channel: European science cut-off?, QJM, 109, (10), 2016
Donnelly, S.C., Management of vasovagal syncope-Where are we today?, QJM, 109, (12), 2016, p765-766
Donnelly, S.C., World pulmonary fibrosis conference-ICLAF 2016, QJM, 109, (9), 2016
Donnelly, S.C., Chronic disease and assessing quality of life?, QJM, 109, (11), 2016
Donnelly, S.C., How do we define when we die?, QJM, 109, (4), 2016
O'Reilly C, Doroudian M, Mawhinney L, Donnelly SC, Targeting MIF in Cancer: Therapeutic Strategies, Current Developments, and Future Opportunities., 2016
Hisert, K.B., Schoenfelt, K.Q., Cooke, G., Grogan, B., Launspach, J.L., Gallagher, C.G., Donnelly, S.C., Welsh, M.J., Singh, P.K., McKone, E.F., Becker, L., Ivacaftor-induced proteomic changes suggest monocyte defects may contribute to the pathogenesis of cystic fibrosis, American Journal of Respiratory Cell and Molecular Biology, 54, (4), 2016, p594-599
Minnis PA, Poland M, Keane MP, Donnelly SC, Adalimumab for refractory pulmonary sarcoidosis., 2015
Kelly D, Donnelly S, Caulfield B, Smartphone derived movement profiles to detect changes in health status in COPD patients - A preliminary investigation., 2015
Donnelly SC, Elements: in this month's issue., 2015
Donnelly SC, Elements: in this month's issue., 2015
Donnelly SC, Elements: in this month's issue., 2015
Mitchell PD, Das JP, Murphy DJ, Keane MP, Donnelly SC, Dodd JD, Butler MW, Idiopathic pulmonary fibrosis with emphysema: evidence of synergy among emphysema and idiopathic pulmonary fibrosis in smokers., 2015
O'Beirne SL, Walsh SM, Fabre A, Reviriego C, Worrell JC, Counihan IP, Lumsden RV, Cramton-Barnes J, Belperio JA, Donnelly SC, Boylan D, Marchal-Sommé J, Kane R, Keane MP, CXCL9 Regulates TGF-ß1-Induced Epithelial to Mesenchymal Transition in Human Alveolar Epithelial Cells., 2015
O'Dwyer DN, Armstrong ME, Kooblall M, Donnelly SC, Targeting defective Toll-like receptor-3 function and idiopathic pulmonary fibrosis., Expert Opin Ther Targets ., 2015
Donnelly SC, Elements: in this month's issue., 2015
Barnes JC, Lumsden RV, Worrell J, Counihan IP, O'Beirne SL, Belperio JA, Fabre A, Donnelly SC, Boylan D, Kane R, Keane MP, CXCR3 Requirement for the Interleukin-13-Mediated Up-Regulation of Interleukin-13R"2 in Pulmonary Fibroblasts., 2015
Donohoe, G., Rose, E., Morris, D., Authors' reply, The British Journal of Psychiatry, 206, (4), 2015, p344-
Lumsden RV, Worrell JC, Boylan D, Walsh SM, Cramton J, Counihan I, O'Beirne S, Medina MF, Gauldie J, Fabre A, Donnelly SC, Kane R, Keane MP, Modulation of pulmonary fibrosis by IL-13R"2., 2015
Brady D, Lavelle LP, McEvoy SH, Murphy DJ, Gallagher A, Gibney B, Butler MW, Shortt F, McMullan M, Fabry A, Lynch DA, Abbara S, Donnelly SC, Dodd JD, Assessing fibrosis in pulmonary sarcoidosis: late-enhanced MRI compared to anatomic HRCT imaging., 2015
Donnelly SC, Elements: in this month's issue., 2015
Caulfield B, Kaljo I, Donnelly S, Use of a consumer market activity monitoring and feedback device improves exercise capacity and activity levels in COPD., 2014
Hams E, Armstrong ME, Barlow JL, Saunders SP, Schwartz C, Cooke G, Fahy RJ, Crotty TB, Hirani N, Flynn RJ, Voehringer D, McKenzie AN, Donnelly SC, Fallon PG, IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis., Proceedings of the National Academy of Sciences of the United States of America, 111, (1), 2014, p367-72
El Ridi R, Tallima H, Dalton JP, Donnelly S, Induction of protective immune responses against schistosomiasis using functionally active cysteine peptidases., 2014
Ballal T, Heneghan C, Zaffaroni A, Boyle P, de Chazal P, Shouldice R, McNicholas WT, Donnelly SC, A pilot study of the nocturnal respiration rates in COPD patients in the home environment using a non-contact biomotion sensor., 2014
Mawhinney L, Armstrong ME, O' Reilly C, Bucala R, Leng L, Fingerle-Rowson G, Fayne D, Keane MP, Tynan A, Maher L, Cooke G, Lloyd D, Conroy H, Donnelly SC, Macrophage migration inhibitory factor (MIF) enzymatic activity and lung cancer., Molecular medicine, 20, (1), 2014, p729 - 735
Donnelly, S.C., The festive season, compassionate communities and society's responsibilities, QJM, 106, (12), 2013
Caulfield BM, Donnelly SC, What is Connected Health and why will it change your practice?, 2013
Donnelly S, Introduction: review series--palliative medicine., 2013
Cooke G, Govender P, Watson CJ, Armstrong ME, O'Dwyer DN, Keane MP, King R, Tynan A, Dunn M, Donnelly SC, Sarcoidosis, alveolar ß-actin and pulmonary fibrosis., QJM, 2013
O'Dwyer DN, Armstrong ME, Cooke G, Dodd JD, Veale DJ, Donnelly SC, Rheumatoid Arthritis (RA) associated interstitial lung disease (ILD)., Eur J Intern Med., 2013
O'Connell C, Hensey M, Mongey AB, Veale DJ, Donnelly SC, A series of patients on anti-TNF therapy referred to a multidisciplinary lung cancer service., 2013
Donnelly SC, Walters M, Reply to: Increased prevalence of sarcoidosis in Ireland., 2013
O'Dwyer D., O'Dwyer D., Armstrong M., Trujillo G., Cooke G., Keane M., Keane M., Fallon P., Simpson A., Millar A., McGrath E., Whyte M., Hirani N., Hogaboam C., Donnelly S., Donnelly S., The toll-like receptor 3 L412F polymorphism and disease progression in idiopathic pulmonary fibrosis, American Journal of Respiratory and Critical Care Medicine, 188, (12), 2013, p1442-1450
O'Dwyer DN, Armstrong ME, Trujillo G, Cooke G, Keane MP, Fallon PG, Simpson AJ, Millar AB, McGrath EE, Whyte MK, Hirani N, Hogaboam CM, Donnelly SC., The Toll-like receptor 3 L412F polymorphism and disease progression in idiopathic pulmonary fibrosis., Am J Respir Crit Care Med., 188, 2013, p1442 - 1450
Cooke, G., Armstrong, M.E., Conroy, H., Donnelly, S.C., MIF and pulmonary disease, The MIF Handbook, 2012, p231-239
Adamali H, Armstrong ME, McLaughlin AM, Cooke G, McKone E, Costello CM, Gallagher CG, Leng L, Baugh JA, Fingerle-Rowson G, Bucala RJ, McLoughlin P, Donnelly SC, Macrophage migration inhibitory factor enzymatic activity, lung inflammation, and cystic fibrosis., Am J Respir Crit Care Med., 186, (2), 2012, p162 - 169
Phelan, D., Watson, C., Martos, R., Collier, P., Patle, A., Donnelly, S., Ledwidge, M., Baugh, J., McDonald, K., Modest Elevation in BNP in Asymptomatic Hypertensive Patients Reflects Sub-Clinical Cardiac Remodeling, Inflammation and Extracellular Matrix Changes, PLoS ONE, 7, (11), 2012
Robinson MW, Hutchinson AT, Donnelly S, Antimicrobial peptides: utility players in innate immunity., 2012
Donnelly SC, Review Series--Inflammation & Fibrosis. Introduction., 2012
Chappell SL, Daly L, Lotya J, Alsaegh A, Guetta-Baranes T, Roca J, Rabinovich R, Morgan K, Millar AB, Donnelly SC, Keatings V, MacNee W, Stolk J, Hiemstra PS, Miniati M, Monti S, O'Connor CM, Kalsheker N, The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study., 2011
Haq, I., Chappell, S., Johnson, S.R., Lotya, J., Daly, L., Morgan, K., Guetta-Baranes, T., Roca, J., Rabinovich, R., Millar, A.B., Donnelly, S.C., Keatings, V., MacNee, W., Stolk, J., Hiemstra, P.S., Miniati, M., Monti, S., O'Connor, C.M., Kalsheker, N., Association of MMP - 12 polymorphisms with severe and very severe COPD: A case control study of MMPs - 1, 9 and 12 in a European population, BMC Medical Genetics, 11, (1), 2010
Conroy H, Mawhinney L, Donnelly SC, Inflammation and cancer: macrophage migration inhibitory factor (MIF)--the potential missing link., 2010
Johnson SR, Cordier JF, Lazor R, Cottin V, Costabel U, Harari S, Reynaud-Gaubert M, Boehler A, Brauner M, Popper H, Bonetti F, Kingswood C, Review Panel of the ERS LAM Task Force, European Respiratory Society guidelines for the diagnosis and management of lymphangioleiomyomatosis., 2010
Govender P, Dunn MJ, Donnelly SC, Proteomics and the lung: Analysis of bronchoalveolar lavage fluid., 2009
Martos, R., Baugh, J., Ledwidge, M., O'Loughlin, C., Murphy, N.F., Conlon, C., Patle, A., Donnelly, S.C., McDonald, K., Diagnosis of heart failure with preserved ejection fraction: Improved accuracy with the use of markers of collagen turnover, European Journal of Heart Failure, 11, (2), 2009, p191-197
Cooke G, Armstrong ME, Donnelly SC, Macrophage migration inhibitory factor (MIF), enzymatic activity and the inflammatory response., BIOFACTORS, 2009
Chappell, S., Daly, L., Morgan, K., Guetta-Baranes, T., Roca, J., Rabinovich, R., Lotya, J., Millar, A.B., Donnelly, S.C., Keatings, V., MacNee, W., Stolk, J., Hiemstra, P.S., Miniati, M., Monti, S., O'Connor, C.M., Kalsheker, N., Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD, European Respiratory Journal, 32, (4), 2008, p931-937
Harte S, McNicholas WT, Donnelly SC, Dodd JD, Honeycomb cysts in idiopathic pulmonary haemosiderosis: high-resolution CT appearances in two adults., 2008
Kevill KA, Bhandari V, Kettunen M, Leng L, Fan J, Mizue Y, Dzuira JD, Reyes-Mugica M, McDonald CL, Baugh JA, O'Connor CL, Aghai ZH, Donnelly SC, Bazzy-Asaad A, Bucala RJ, A role for macrophage migration inhibitory factor in the neonatal respiratory distress syndrome., 2008
Armstrong ME, Gantier M, Li L, Chung WY, McCann A, Baugh JA, Donnelly SC, Small interfering RNAs induce macrophage migration inhibitory factor production and proliferation in breast cancer cells via a double-stranded RNA-dependent protein kinase-dependent mechanism., J Immunol., 2008
Laughlin, A.M., O'Brien, R., Donnelly, S.C., Familial idiopathic pulmonary fibrosis occurring in four members of a family, Respiratory Medicine Extra, 3, (1), 2007, p23-25
Plant, B.J., Ghani, S., O'Mahony, M.J., Morgan, L., O'Connor, C.M., Morgan, K., Baugh, J.A., Donnelly, S.C., Erratum: "Sarcoidosis and MIF gene polymorphism: A case-control study in an Irish population" (European Respiratory Journal (2007) vol. 29 (325-329)), European Respiratory Journal, 30, (2), 2007
Martos R, Baugh J, Ledwidge M, O'Loughlin C, Conlon C, Patle A, Donnelly SC, McDonald K, Diastolic heart failure: evidence of increased myocardial collagen turnover linked to diastolic dysfunction., 2007
Plant BJ, Ghani S, O'Mahony MJ, Morgan L, O'Connor CM, Morgan K, Baugh JA, Donnelly SC, Sarcoidosis and MIF gene polymorphism: a case-control study in an Irish population., 2007
Gantier MP, Baugh JA, Donnelly SC, Nuclear transcription of long hairpin RNA triggers innate immune responses., 2007
Govender P, Baugh JA, Pennington SR, Dunn MJ, Donnelly SC, Role of proteomics in the investigation of pulmonary fibrosis., 2007
Chappell S, Daly L, Morgan K, Baranes TG, Roca J, Rabinovich R, Millar A, Donnelly SC, Keatings V, Macnee W, Stolk J, Hiemstra PS, Miniati M, Monti S, O'Connor CM, Kalsheker N, Variation in the tumour necrosis factor gene is not associated with susceptibility to COPD., 2007
Foley SC, Hopkins NO, Fitzgerald MX, Donnelly SC, McLoughlin P, Airway nitric oxide output is reduced in bronchiectasis., 2007
Cedervall T, Lynch I, Foy M, Berggård T, Donnelly SC, Cagney G, Linse S, Dawson KA, Detailed identification of plasma proteins adsorbed on copolymer nanoparticles., 2007
Bucala R, Donnelly SC, Macrophage migration inhibitory factor: a probable link between inflammation and cancer., 2007
Chappell S, Daly L, Morgan K, Guetta Baranes T, Roca J, Rabinovich R, Millar A, Donnelly SC, Keatings V, MacNee W, Stolk J, Hiemstra P, Miniati M, Monti S, O'Connor CM, Kalsheker N, Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease., 2006
Naji NA, Connor MC, Donnelly SC, McDonnell TJ, Effectiveness of pulmonary rehabilitation in restrictive lung disease., 2006
Chappell S, Daly L, Morgan K, Baranes TG, Roca J, Rabinovich R, Millar A, Donnelly SC, Keatings V, MacNee W, Stolk J, Hiemstra PS, Miniati M, Monti S, O'Connor CM, Kalsheker N, The SERPINE2 gene and chronic obstructive pulmonary disease., 2006
Baugh JA, Gantier M, Li L, Byrne A, Buckley A, Donnelly SC, Dual regulation of macrophage migration inhibitory factor (MIF) expression in hypoxia by CREB and HIF-1., 2006
Mizue Y, Ghani S, Leng L, McDonald C, Kong P, Baugh J, Lane SJ, Craft J, Nishihira J, Donnelly SC, Zhu Z, Bucala R, Role for macrophage migration inhibitory factor in asthma., 2005
Plant BJ, Gallagher CG, Bucala R, Baugh JA, Chappell S, Morgan L, O'Connor CM, Morgan K, Donnelly SC, Cystic fibrosis, disease severity, and a macrophage migration inhibitory factor polymorphism., 2005
Butler MW, O'Mahony MJ, Donnelly SC, McDonnell TJ, Managing exacerbations of COPD: room for improvement., 2004
Fisher AJ, Donnelly SC, Pritchard G, Dark JH, Corris PA, Objective assessment of criteria for selection of donor lungs suitable for transplantation., 2004
Pan JH, Lindholt JS, Sukhova GK, Baugh JA, Henneberg EW, Bucala R, Donnelly SC, Libby P, Metz C, Shi GP, Macrophage migration inhibitory factor is associated with aneurysmal expansion., 2003
Baugh JA, Donnelly SC, Macrophage migration inhibitory factor: a neuroendocrine modulator of chronic inflammation., 2003
Leng L, Metz CN, Fang Y, Xu J, Donnelly S, Baugh J, Delohery T, Chen Y, Mitchell RA, Bucala R, MIF signal transduction initiated by binding to CD74., 2003
Butler MW, Mullan RH, Schaffer KE, Crotty TB, Luke DA, Donnelly SC, Pulmonary cystic hydatid disease in Ireland., 2003
Kurdowska A, Noble JM, Grant IS, Robertson CR, Haslett C, Donnelly SC, Anti-interleukin-8 autoantibodies in patients at risk for acute respiratory distress syndrome., 2002
Atsumi T, Chesney J, Metz C, Leng L, Donnelly S, Makita Z, Mitchell R, Bucala R, High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers., 2002
Baugh JA, Chitnis S, Donnelly SC, Monteiro J, Lin X, Plant BJ, Wolfe F, Gregersen PK, Bucala R, A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis., 2002
Keane MP, Donnelly SC, Belperio JA, Goodman RB, Dy M, Burdick MD, Fishbein MC, Strieter RM, Imbalance in the expression of CXC chemokines correlates with bronchoalveolar lavage fluid angiogenic activity and procollagen levels in acute respiratory distress syndrome., 2002
Hirani N, Antonicelli F, Strieter RM, Wiesener MS, Ratcliffe PJ, Haslett C, Donnelly SC, The regulation of interleukin-8 by hypoxia in human macrophages--a potential role in the pathogenesis of the acute respiratory distress syndrome (ARDS)., 2001
Fisher AJ, Donnelly SC, Hirani N, Haslett C, Strieter RM, Dark JH, Corris PA, Elevated levels of interleukin-8 in donor lungs is associated with early graft failure after lung transplantation., 2001
Abe R, Donnelly SC, Peng T, Bucala R, Metz CN, Peripheral blood fibrocytes: differentiation pathway and migration to wound sites., 2001
Reid PT, Donnelly SC, MacGregor IR, Grant IS, Cameron E, Walker W, Merrick MV, Haslett C, Pulmonary endothelial permeability and circulating neutrophil-endothelial markers in patients undergoing esophagogastrectomy., 2000
Sethi T, Rintoul RC, Moore SM, MacKinnon AC, Salter D, Choo C, Chilvers ER, Dransfield I, Donnelly SC, Strieter R, Haslett C, Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo., 1999
Hirani, N., Antonicelli, F., Haslett, C., Donnelly, S.C., The selective upregulation of Interleukin 8 (IL-8) from hypoxic human macrophages - A potential role in the Acute Respiratory Distress Syndrome (ARDS), Thorax, 54, (SUPPL. 3), 1999
Fisher AJ, Donnelly SC, Hirani N, Burdick MD, Strieter RM, Dark JH, Corris PA, Enhanced pulmonary inflammation in organ donors following fatal non-traumatic brain injury., 1999
Donnelly SC, Bucala R, Metz CN, Grant IS, Robertson CR, Haslett C, Macrophage migration inhibitory factor and acute lung injury., 1999
Strieter, R.M., Miller, E.J., Kurdowska, A.K., Reid, P.T., Donnelly, S.C., Measurement of cytokines in bronchoalveolar lavage fluid, European Respiratory Review, 9, (66), 1999, p106-112
Hirani, N., Clay, M., Sri-Pathmanathan, R., Sharkey, R., Haslett, C., Donnelly, S.C., A role for acute Hypoxia/Hyperoxia in the pathogenesis of the Acute Respiratory Distress Syndrome (ARDS) - An in vivo model, Thorax, 54, (SUPPL. 3), 1999
Fisher, A.J., Donnelly, S.C., Hirani, N., Haslett, C., Strieter, R.M., Dark, J.H., Corris, P.A., The effect of donor lung inflammation on outcome following human lung transplantation, Thorax, 54, (SUPPL. 3), 1999
Sharkey RA, Donnelly SC, Connelly KG, Robertson CE, Haslett C, Repine JE, Initial serum ferritin levels in patients with multiple trauma and the subsequent development of acute respiratory distress syndrome., 1999
Sallenave JM, Donnelly SC, Grant IS, Robertson C, Gauldie J, Haslett C, Secretory leukocyte proteinase inhibitor is preferentially increased in patients with acute respiratory distress syndrome., 1999
Hennessy, T.G., Codd, M.B., Donnelly, S., Hartigan, C., McCann, H.A., McCarthy, C., Neligan, M., Wood, A.E., Luke, D., McGovern, E., Aherne, T., Sugrue, D.D., Long-term clinical outcome following coronary artery bypass grafting for isolated stenosis of the left anterior descending coronary artery, European Heart Journal, 19, (3), 1998, p447-457
Sharkey, R.A., Kalsheker, N., Morgan, K., Cave, S., Grant, I.S., Haslett, C., Donnelly, S.C., Association between polymorphism in gene for microsomal epoxide hydrolase and the Acute Respiratory Distress Syndrome (ARDS), Thorax, 53, (SUPPL. 4), 1998
Ruchaud-Sparagano MH, Drost EM, Donnelly SC, Bird MI, Haslett C, Dransfield I, Potential pro-inflammatory effects of soluble E-selectin upon neutrophil function., 1998
Rossi AG, Haslett C, Hirani N, Greening AP, Rahman I, Metz CN, Bucala R, Donnelly SC, Human circulating eosinophils secrete macrophage migration inhibitory factor (MIF). Potential role in asthma., 1998
Hirani, N., Haslett, C., Donnelly, S.C., Hypoxic upregulation of IL8 in human macrophages - The role of transcription factors AP-1 and C/EBP, Thorax, 53, (SUPPL. 4), 1998
Morrison D, Strieter RM, Donnelly SC, Burdick MD, Kunkel SL, MacNee W, Neutrophil chemokines in bronchoalveolar lavage fluid and leukocyte-conditioned medium from nonsmokers and smokers., 1998
Donnelly SC, Bucala R, Macrophage migration inhibitory factor: a regulator of glucocorticoid activity with a critical role in inflammatory disease., 1997
Hirani, N., Haslett, C., Donnelly, S.C., Influence of hypoxia in augmenting IL-8 generation from human monocytes and macropghages - Potential role in the acute respiratory distress syndrome, Thorax, 52, (SUPPL. 6), 1997
Donnelly SC, Haslett C, Reid PT, Grant IS, Wallace WA, Metz CN, Bruce LJ, Bucala R, Regulatory role for macrophage migration inhibitory factor in acute respiratory distress syndrome., 1997
MacGregor IR, Perrie AM, Donnelly SC, Haslett C, Modulation of human endothelial thrombomodulin by neutrophils and their release products., 1997
Donnelly SC, Strieter RM, Reid PT, Kunkel SL, Burdick MD, Armstrong I, Mackenzie A, Haslett C, The association between mortality rates and decreased concentrations of interleukin-10 and interleukin-1 receptor antagonist in the lung fluids of patients with the adult respiratory distress syndrome., 1996
Reid PT, Donnelly SC, Predicting acute respiratory distress syndrome and intrapulmonary inflammation., 1996
Rahman, I., Haslett, C., Rossi, A., Reid, P.T., Wallace, W., Bucala, R., Metz, C., Donnelly, S.C., Epithelial cells are a source for macrophage Migration Inhibitory Factor (MIF) - Potential role in Acute Respiratory Distress Syndrome (ARDS), Thorax, 51, (SUPPL. 3), 1996
Morrison, D., Strieter, R.M., Donnelly, S., Burdick, M.D., Kunkel, S.L., Macnee, W., Epithelial permeability in vivo and in vitro and TNF" in non-smokers and smokers, Thorax, 51, (SUPPL. 3), 1996
Donnelly, S.C., Strieter, R.M., Reid, P.T., Kunkel, S.L., Burdick, M.D., Armstrong, I., Mackenzie, A., Haslett, C., The Association between Mortality Rates and Decreased Concentrations of Interleukin-10 and Interleukin-1 Receptor Antagonist in the Lung Fluids of Patients with the Adult Respiratory Distress Syndrome, Annals of Internal Medicine, 125, (3), 1996, p191-196
Reid PT, Donnelly SC, Haslett C, Inflammatory predictors for the development of the adult respiratory distress syndrome., 1995
Donnelly SC, MacGregor I, Zamani A, Gordon MW, Robertson CE, Steedman DJ, Little K, Haslett C, Plasma elastase levels and the development of the adult respiratory distress syndrome., 1995
Donnelly SC, Corticosteroids and "chronic" ARDS., 1995
Donnelly SC, Strieter RM, Kunkel SL, Walz A, Steedman D, Grant IS, Pollok AJ, Carter DC, Haslett C, Chemotactic cytokines in the established adult respiratory distress syndrome and at-risk patients., 1994
Donnelly SC, Haslett C, Dransfield I, Robertson CE, Carter DC, Ross JA, Grant IS, Tedder TF, Role of selectins in development of adult respiratory distress syndrome., 1994
Shelly, M.P., Kelly, K., Grant, I., Donnelly, S., Fearon, K., Kinsella, J., Nightingale, P., Howie, J.C., Masterton, R., Nimmo, G.R., Grand Round in intensive care, Clinical Intensive Care, 5, (5), 1994, p248-254
Donnelly SC, Robertson C, Mediators, mechanisms and mortality in major trauma., 1994
Mulherin, D., FitzGerald, O., Bresnihan, B., Bruce, I.N., McNally, J.A., Bell, A.L., Yanni, G., Cauli, A., Challacombe, S., Panayi, G.S., Foley-Nolan, D., Akil, M., Anthony, M., Cundall, D., Bourne, J., Arthur, R., Chamberlain, M.A., Byrne, P., Mahon, N., Robinson, H., Sant, S.M., Donnelly, S., Barnes, L., Watson, R., Casey, E.B., Donnelly, S., Casey, E.B., Bruce, I.N., Edgar, D.E., McMillan, S.A., Conlan, S.K., McNeill, T.A., Bell, A.L., Robinson, H., Byrne, P., Mahon, N., Sant, S.M., Abuzakouk, M., Feighery, C., Jones, E., O"Briain, S., Goggins, M., Weir, D.G., Casey, E., O"Farrelly, C., Kelleher, D., Murphy, A., Casey, E.B., Veale, D.J., Kirk, G., McLaren, M., Belch, J.J.F., Byrne, P., Mahon, N., Robinson, H., Sant, S.M., Foley-Nolan, D., Daly, M.J., Mahon, N., Robinson, H., Byrne, P., Sant, S.M., Donnelly, S., Murphy, J., Lynch, M., Casey, E.B., McKernan, S., Donnelly, S., Casey, E.B., Sothinathan, R., Donnelly, S., Casey, E.B., Blake, C., Garrett, M., Robinson, H., Byrne, P., Mahon, N., Sant, S.M., Gourley, I.S., Bell, A.L., Bresnihan, B., FitzGerald, O., Cunnane, G., Abuzakouk, M., Feighery, C., Bergin, C., Cherukuri, A., Weir, D.G., Casey, E., O"Farrelly, C., Mulherin, D., Kirk, G., Veale, D.J., Belch, J.J.F., Bresnihan, B., FitzGerald, O., Kelleher, D., Hall, N., Murphy, A., Casey, E.B., Mulcahy, B., Molloy, M., Phelan, M., O"Gara, F., McConnell, F., Shanahan, F., FitzGerald, O., Heffernan, M., Mulcahy, B., Neary, P., Molloy, M., Irish society for rheumatology: Proceedings of annual general meeting held in Beaumont Hospital on Friday 22nd October, 1993, Irish Journal of Medical Science, 163, (4), 1994, p188-195
Chan, K.H., Singh, H.P., Aherne, T., Carabine, U., Gilliland, H., Johnston, J.R., Lowry, K.G., McGuigan, J., Cosgrove, J., Veerasingham, D., McCarthy, J., Hurley, J., Wood, A.E., Gilliland, R., McGuigan, J.A., McManus, K.G., Wilkinson, P., Johnston, L.C., MacMahon, J., Wilson, D., Austin, C., Anikin, V., McManus, K., McGuigan, J., McManus, K., Anikin, V., Gibbons, J.R.P., McGuigan, J., Sharkey, R., Long, M., Maree, A., O"Neill, S., Maguire, C.P., Hayes, J.P., Masterson, J., Fitzgerald, M.X., Hayes, M., Maguire, C.P., Hayes, J.P., Masterson, J., Fitzgerald, M.X., Quigley, C., Mofidi, A., Mofidi, R., Fitzgerald, M.X., O"Neill, M., Watson, J.B.G., O"Halloran, E.T., Shortt, C., Taylor, M., Holland, C., O"Lorcain, P., Taylor, M., Holland, C., O"Lorcain, P., Pathmakanthan, S., Sreenan, S., Power, C.K., Poulter, L.W., Burke, C.M., Reilly, D., Pathmakanthan, S., Sreenan, S., Doyle, S., Burke, C.M., Sreenan, S., Power, C., Pathmakanthan, S., Goggin, A., Burke, C.M., Poulter, L.W., Sreenan, S., Doyle, S., Pathmakanthan, S., Poulter, L.W., Burke, C.M., Sreenan, S., Debenham, P., Pathmakanthan, S., Burke, C.M., Poulter, L.W., Southey, A., O"Connor, C.M., Fitzgerald, M.X., Bourke, W.J., McDonnell, T.J., Buck, J.B., Magee, T.R.A., Lowry, R.C., Graham, A.N.J., Owens, W.A., Kelly, S.B., McGuigan, J.A., Costelloe, R.W., Ryan, J., Collins, J., Guerin, D., Rooney, D., Long, E., O"Donnell, M., O"Neill, S., Cotter, T.P., Bredin, C.P., Buick, J.B., Lowry, R.C., MacMahon, J.J., Finlay, G., Concannon, D., McDonnell, T.J., Reid, P.T., Alderdice, J., Carson, J., Sinnamon, D.G., Murphy, S., Scott, T., Keane, C.T., Walsh, J.B., Coakley, D., McKeown, D., Kelly, P., Clancy, L., Kiely, J.L., Cryan, B., Bredin, C.P., Killeen, P., Farrell, S., Kelly, P., Clancy, L., Kiely, J.L., O"Riordan, D.M., Sheehan, S., Curtain, J., Hogan, J., Bredin, C.P., Malone, A., Ahmed, S., Watson, J.B.G., Murphy, M., Fennell, W., Ahmed, S., Watson, J.B.G., Aherne, T., Keohane, C., O"Neill, M., Gleeson, C.M., McGuigan, J., Ritchie, A.J., Russell, S.E.H., Molloy, E., Keane, M., Coakley, R., Costello, R., Condron, C., Watson, R.G.W., O"Neill, S., Kelly, C., Redmond, H., Watson, W., Burke, P., Bouchier-Hayes, D., Donnelly, S.C., Haslett, C., Dransfield, I., Robertson, C.E., Carter, D.C., Ross, J.A., Grant, I.S., Tedder, T.F., Doyle, S., Sreenan, S., Pathmakanthan, S., Burke, C.M., Heaney, L.G., Cross, L.J.M., Stanford, C.F., Ennis, M., Sreenan, S., Pathmakanthan, S., Power, C., Goggin, A., Poulter, L.W., Burke, C.M., Murphy, S., Scott, T., Keane, C.T., Walsh, J.B., Coakley, D., O"Riordan, D.M., Gergely, L., Deng, N., Rose, R.M., Hennessy, T., Hickey, L., Thornton, L., Collum, C., Durity, M., Power, J., Johnson, H., Lee, B., Doherty, E., Kelly, E., McDonnell, T., McKeown, D., Kelly, P., Clancy, L., Wilkinson, P., Varghese, G., Anikin, V., Gibbons, J., McManus, K., McGuigan, J., Reid, P.T., Gower, N.H., Rudd, R.M., Irish thoracic society: Proceedings of annual scientific meeting held in Cork on 5th & 6th November, 1993, Irish Journal of Medical Science, 163, (4), 1994, p196-211
Cullen, C., MacKenzie, G., Adgey, J., Lavin, F., Keane, M., Forde, A., Shah, P., Gannon, F., Daly, K., McClements, B.M., McNeil, A.J., Wilson, C.M., Webb, S.W., Campbell, N.P.S., Khan, M.M., O'Murchu, B., Gersh, B.J., Bailey, K.R., Holmes, D.R., Foley, D.P., Hermans, W.R., Rensing, B.J., Vos, J., Herman, J.-P., Serruys, P.W., Mannion, A., Finn, J., Grimes, H., Lonergan, M., O'Donnell, Daly, L., McGovern, E., Graham, I., Joseph, P.A., Robinson, K., Kinsella, T., Crean, P., Gearty, G., Walsh, M., Ryan, M., Clarke, R., Refsum, R., Ueland, P., Coehrane, D.J., Stewart, A.J., McEneaney, D.J., Allen, J.D., Anderson, J., Dempsey, G., Adgey, A.A.J., Casey, F.A., Mulholland, H.C., Craig, B.G., Power, R., Rooney, N., O'Keeffe, D.B., McComb, J., Wilson, C., Tan, K.S., Pye, C., McCabe, N., Hickey, N., McEneaney, D., Cochrane, D., Oslizlok, P.C., Case, C.L., Gillette, P.C., Knick, B.J., Henry, L.P.N., Blair, L., Gumbrielle, T., Bourke, J.P., Hilton, C.J., Campbell, R.W.F., Kearney, P.P., Fennell, F., McKiernan, S., Fennell, W., Escaned, J., Hermans, W.R., Umans, V.A., de Jaegere, P.P., de Feyter, P.J., Galvin, J., Leavey, S., Sugrue, D., Vallely, S.R., Campbell, N.P.S., Laird, J.D., Ferguson, R., Duff, S., Bridges, A.B., Pringle, T.H., McNeill, G.P., McLaren, M., Belch, J.J.F., O'Sullivan, L., Bain, H., Hunter, S., Wren, C., Hennesy, A., Codd, M., Daly, C., McCarthy, C., Carroll, K., Coakley, F., O'Mahony, S., Sullivan, P.A., Kearney, P., Higgins, T., Crowey, J.J., Donnelly, S.M., Tobin, M., FitzGerald, O., Bresnihan, B., Maurer, B.J., Quigley, P.J., Shelley, E., Collins, C., Hickey, N., ulcahy, R., Johnston, P.W., Gibson, J., Crowe, P., King, G., Freyne, P.J., Geary, G., McAdam, B., Sheahan, R., Gaylani, N.E., Simpson, A., Temperley, I., Mulcahy, F., McGee, H.M., Graham, T., Crowe, B., Horgan, J.H., McGinley, J., Hurley, J., Neligan, M., Austin, C., Cleland, J., Gladstone, D., O'Kane, H., O'Sullivan, J., Hasan, A., Hamilton, J.R.L., Hunter, S., Dark, J.H., McDaid, C.M., Phillips, A.S., Lewis, S.A., McMurray, T.J., Walsh, K.P., Abrams, S.E., Diamond, M., Clarkson, M.J., Rutsch, W., Emanuelsson, H., Danchin, N., Wijns, W., Chappuis, F., Irish cardiac society - Proceedings of annual general meeting held 20th & 21st November 1992 in Dublin Castle, Irish Journal of Medical Science, 162, (5), 1993, p195-207
Carey FA, Donnelly SC, Walker WS, Cameron EW, Lamb D, Synchronous primary lung cancers: prevalence in surgical material and clinical implications., 1993
Donnelly SC, Robertson C, Trauma, inflammatory cells and ARDS., 1993
Donnelly SC, Strieter RM, Kunkel SL, Walz A, Robertson CR, Carter DC, Grant IS, Pollok AJ, Haslett C, Interleukin-8 and development of adult respiratory distress syndrome in at-risk patient groups., 1993
Haslett C, Donnelly SC, AUTHORS' REPLY., 1992
Donnelly SC, Haslett C, Cellular mechanisms of acute lung injury: implications for future treatment in the adult respiratory distress syndrome., 1992
Donnelly SC, Hogan JM, Bredin CP, Sudden death from primary B-cell non-Hodgkin's lymphoma of the larynx., 1991
Donnelly SC, McLaughlin H, Bredin CP, Period prevalence of allergic bronchopulmonary mycosis in a regional hospital outpatient population in Ireland 1985-88., 1991
Donnelly S, Ward K, FitzGerald MX, Analysis of patients lost to follow up at a sarcoid clinic., 1991
Donnelly S, Callaghan N, Subacute combined degeneration of the spinal cord due to folate deficiency in association with a psychotic illness., 1990
Donnelly SC, FitzGerald MX, Reactive airways dysfunction syndrome (RADS) due to chlorine gas exposure., 1990
Breen, E.G., Donnelly, S., Alopecia associated with sulphasalazine (Salazopyrine), British Medical Journal, 292, (6523), 1986
Non-Peer-Reviewed Publications
Dr Jane Humphries, Elements, Irish Art Review, 29, (4), 2012, p76 - 77