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Professor Owen Corrigan
Fellow Emeritus, Pharmacy

Biography

Professor of Pharmaceutics. Have acted as consultant on occasion to Leo Laboratories Ltd., Mycopharm Ltd., Tanabe Ltd., Newport Pharmaceuticals Ltd., ICP Ltd., Revlon Healthcare Ltd., Sandoz AG, The Cross Chemical Group, Hill & Knowlton Ltd., and The Health Education Bureau. . EXTERNAL EXAMINER FOR PH.D. THESIS FOR: University of Bradford, University of London, University of Manchester, University of Strathclyde, The Queens University Belfast, University of Uppsala, Sweden and John Mores University Liverpool .

. ACTED AS REVIEWER/ REFEREE FOR THE FOLLOWING JOURNALS: Journal of Pharmaceutical Sciences Pharmaceutical Research International Journal of Pharmaceutics Journal of Controlled Release Journal of Pharmacy and Pharmacology European Journal of Pharmaceutical Sciences Biopharmaceutics and Drug Disposition. Thermochemica Acta Biomacromolicules

Publications and Further Research Outputs

Peer-Reviewed Publications

Deirdre M D'Arcy, Owen I Corrigan, Evelyn Deasy, Caitríona M Gowing, Maria B Donnelly, Gentamicin pharmacokinetics in critically ill patients during treatment with continuous venovenous haemodiafiltration (CVVHDF), European Journal of Clinical Pharmacology, 71, (3), 2015, p377 - 378 Journal Article, 2015

Umerska A, Corrigan OI, Tajber L, Intermolecular interactions between salmon calcitonin, hyaluronate, and chitosan and their impact on the process of formation and properties of peptide-loaded nanoparticles., International Journal of Pharmaceutics, 477, (1-2), 2014, p102 - 112 Journal Article, 2014 TARA - Full Text DOI

Umerska A, Paluch KJ, Santos-Martinez MJ, Corrigan OI, Medina C, Tajber L, Self-assembled hyaluronate/protamine polyelectrolyte nanoplexes: synthesis, stability, biocompatibility and potential use as peptide carriers, Journal of Biomedical Nanotechnology, 10, (12), 2014, p3658 - 3673 Journal Article, 2014 DOI TARA - Full Text

Ryan, S.M., McMorrow, J., Umerska, A., Patel, H.B., Kornerup, K.N., Tajber, L., Murphy, E.P., Perretti, M., Corrigan, O.I., Brayden, D.J., An intra-articular salmon calcitonin-based nanocomplex reduces experimental inflammatory arthritis, Journal of Controlled Release, 167, (2), 2013, p120-129 Journal Article, 2013 DOI

Paluch, K.J., Tajber, L., Corrigan, O.I., Healy, A.M., Impact of alternative solid state forms and specific surface area of high-dose, hydrophilic active pharmaceutical ingredients on tabletability, Molecular Pharmaceutics, 10, (10), 2013, p3628-3639 Journal Article, 2013 DOI

Caron, V., Hu, Y., Tajber, L., Erxleben, A., Corrigan, O.I., McArdle, P., Healy, A.M., Amorphous solid dispersions of sulfonamide/soluplus® and sulfonamide/PVP prepared by ball milling, AAPS PharmSciTech, 14, (1), 2013, p464-474 Journal Article, 2013 DOI

Paluch, K.J., McCabe, T., MÃ"ller-Bunz, H., Corrigan, O.I., Healy, A.M., Tajber, L., Formation and physicochemical properties of crystalline and amorphous salts with different stoichiometries formed between ciprofloxacin and succinic acid, Molecular Pharmaceutics, 10, (10), 2013, p3640-3654 Journal Article, 2013 DOI

Curtin, V., Amharar, Y., Gallagher, K.H., Corcoran, S., Tajber, L., Corrigan, O.I., Healy, A.M., Reducing mechanical activation-induced amorphisation of salbutamol sulphate by co-processing with selected carboxylic acids, International Journal of Pharmaceutics, 456, (2), 2013, p508-516 Journal Article, 2013 DOI

Curtin, V., Amharar, Y., Hu, Y., Erxleben, A., McArdle, P., Caron, V., Tajber, L., Corrigan, O.I., Healy, A.M., Investigation of the capacity of low glass transition temperature excipients to minimize amorphization of sulfadimidine on comilling, Molecular Pharmaceutics, 10, (1), 2013, p386-396 Journal Article, 2013 DOI

Malone, M.E., Corrigan, O.I., Kavanagh, P.V., Gowing, C., Donnelly, M., D'Arcy, D.M., Pharmacokinetics of amphotericin B lipid complex in critically ill patients undergoing continuous venovenous haemodiafiltration, International Journal of Antimicrobial Agents, 42, (4), 2013, p335-342 Journal Article, 2013 DOI

Bianco S, Caron V, Tajber L, Corrigan OI, Nolan LM, Hu Y, Healy AM, Modification of the solid state nature of sulfathiazole and sulfathiazole sodium by spray drying, AAPS PharmSciTech, 13, (2), 2012, p647 - 660 Journal Article, 2012 DOI

Gad S, Tajber L, Corrigan OI Healy AM, Preparation and characterisation of novel spray dried nano-structured para-aminosalicylic acid particulates for pulmonary delivery: impact of ammonium carbonate on morphology, chemical composition and solid state, Journal of Pharmacy and Pharmacology, 64, (9), 2012, p1264 - 1274 Journal Article, 2012 DOI TARA - Full Text

Ní Ógáin O, Tajber L, Corrigan OI, Healy AM, Spray drying from organic solvents to prepare nanoporous/nanoparticulate microparticles (NPMPs) of protein:excipient composites designed for oral inhalation, Journal of Pharmacy and Pharmacology, 64, (9), 2012, p1275 - 1290 Journal Article, 2012 DOI TARA - Full Text

Paluch KJ, Tajber L, Corrigan OI, Healy AM, Impact of process variables on the micromeritic and physicochemical properties of spray dried porous microparticles - Part I. Introduction of a new Morphology Classification System, Journal of Pharmacy and Pharmacology, 64, (11), 2012, p1570 - 1582 Journal Article, 2012 DOI TARA - Full Text

Paluch KJ, Tajber L, Adamczyk B, Corrigan OI, Healy AM, A novel approach to crystallisation of nanodispersible microparticles by spray drying for improved tabletability, International Journal of Pharmaceutics, 436, (1-2), 2012, p873 - 876 Journal Article, 2012 URL DOI

M.E. Malone, C. Gowing, M. Barry, E. Deasy, P. Kavanagh, O.I. Corrigan, D.M. D'Arcy, M. Donnelly, CAN ROUTINE CLINICAL CHEMISTRY RESULTS BE RELATED TO THE VOLUME OF DISTRIBUTION OF AMPHOTERICIN B LIPID COMPLEX IN CRITICALLY ILL PATIENTS?, Intensive Care Medicine, European Society of Intensive Care Medicine, 25th Annual Congress, Lisbon, Portugal, October 13-17 2012, 38, (Supplement 1), 2012, pp0548- Meeting Abstract, 2012

Mori, A., Oleszycka, E., Sharp, F.A., Coleman, M., Ozasa, Y., Singh, M., O'Hagan, D.T., Tajber, L., Corrigan, O.I., McNeela, E.A., Lavelle, E.C., The vaccine adjuvant alum inhibits IL-12 by promoting PI3 kinase signaling while chitosan does not inhibit IL-12 and enhances Th1 and Th17 responses, European Journal of Immunology, 42, (10), 2012, p2709-2719 Journal Article, 2012 DOI

Paluch KJ, Amaro MI, Tajber L, Corrigan OI, Healy AM, Impact of process variables on the micromeritic and physicochemical properties of spray dried microparticles - Part II. Physicochemical characterisation of spray dried materials, Journal of Pharmacy and Pharmacology, 64, (11), 2012, p1583 - 1591 Journal Article, 2012 TARA - Full Text DOI

D'Arcy, D.M., Casey, E., Gowing, C.M., Donnelly, M.B., Corrigan, O.I., An open prospective study of amikacin pharmacokinetics in critically ill patients during treatment with continuous venovenous haemodiafiltration, BMC Pharmacology and Toxicology, 13, 2012 Journal Article, 2012 DOI

Grossjohann C, Eccles KS, Maguire AR, Lawrence SE, Tajber L, Corrigan OI, Healy AM, Characterisation, solubility and intrinsic dissolution behaviour of benzamide:dibenzyl sulfoxide cocrystal, International Journal of Pharmaceutics, 422, (1-2), 2012, p24-32 Journal Article, 2012 TARA - Full Text DOI

Umerska A, Paluch KJ, Inkielewicz-Stępniak I, Santos-Martinez MJ, Corrigan OI, Medina C, Tajber L., Exploring the assembly process and properties of novel crosslinker-free hyaluronate-based polyelectrolyte complex nanocarriers, International Journal of Pharmaceutics, 436, (1-2), 2012, p75 - 87 Journal Article, 2012 TARA - Full Text DOI URL

Tewes F, Gobbo OL, Amaro MI, Tajber L, Corrigan OI, Ehrhardt C, Healy AM, Evaluation of HPβCD-PEG microparticles for salmon calcitonin administration via pulmonary delivery, Molecular Pharmaceutics, 8, (5), 2011, p1887 - 1898 Journal Article, 2011 DOI

Paluch K, Tajber L, Elcoate CJ, Corrigan OI, Lawrence SE, Healy AM, Solid state characterisation of novel active pharmaceutical ingredients: co-crystal of a salbutamol hemiadipate salt with adipic acid (2:1:1) and salbutamol hemisuccinate salt, Journal of Pharmaceutical Sciences, 100, (8), 2011, p3268 - 3283 Journal Article, 2011 TARA - Full Text DOI

Ní Ógáin O, Li J, Tajber L, Corrigan OI, Healy AM, Particle engineering of materials for oral inhalation by dry powder inhalers. I - Particles of sugar excipients (trehalose and raffinose) for protein delivery, International Journal of Pharmaceutics, 405, (1-2), 2011, p23 - 35 Journal Article, 2011 DOI TARA - Full Text

Deirdre M. D'Arcy, Bo Liu, Owen I. Corrigan, Investigating the effect of solubility and density gradients on local hydrodynamics and drug dissolution in the USP 4 dissolution apparatus, International Journal of Pharmaceutics, 419, (1-2), 2011, p175-185 Journal Article, 2011 TARA - Full Text

Nolan LM, Li J, Tajber L, Corrigan OI, Healy AM, Particle engineering of materials for oral inhalation by dry powder inhalers. II - Sodium cromoglicate, International Journal of Pharmaceutics, 405, (1-2), 2011, p36 - 46 Journal Article, 2011 DOI TARA - Full Text

Spooner AM, Deegan C, D'Arcy DM, Gowing CM, Donnelly MB, Corrigan OI, An evaluation of ciprofloxacin pharmacokinetics in critically ill patients undergoing continuous veno-venous haemodiafiltration., BMC Clinical Pharmacology, 11, (1), 2011, p11 Journal Article, 2011 TARA - Full Text DOI URL

Amaro MI, Tajber L, Corrigan OI, Healy AM, Optimisation of spray drying process conditions for sugar nanoporous microparticles (NPMPs) intended for inhalation, International Journal of Pharmaceutics, 421, (1), 2011, p99 - 109 Journal Article, 2011 DOI TARA - Full Text

Parojcic, J, Stojkovic, A, Tajber, L, Grbic, S, Paluch, KJ, Djuric, Z, Corrigan, OI, Biopharmaceutical Characterization of Ciprofloxacin HCl-Ferrous Sulfate Interaction, JOURNAL OF PHARMACEUTICAL SCIENCES, 100, 2011 Journal Article, 2011

Caron V, Tajber L, Corrigan OI, Healy AM, A comparison of spray drying and milling in the production of amorphous dispersions of sulfathiazole/polyvinylpyrrolidone and sulfadimidine/polyvinylpyrrolidone, Molecular Pharmaceutics, 8, (2), 2011, p532 - 542 Journal Article, 2011 DOI

Paluch KJ, Tajber L, McCabe T, O'Brien JE, Corrigan O, Healy AM, Preparation and characterisation of novel chlorothiazide potassium solid-state salt forms: intermolecular self assembly suprastructures, European Journal of Pharmaceutical Sciences, 42, (3), 2011, p220 - 229 Journal Article, 2011 TARA - Full Text DOI

Paluch, K.J., Tajber, L., McCabe, T., O'Brien, J.E., Corrigan, O.I., Healy, A.M., Salt or intermolecular self-assembly - physicochemical analysis of crystalline chlorothiazide and chlorothiazide sodium, All Ireland Schools of Pharmacy 32nd Research Seminar, Belfast, 2010, 2010 Poster, 2010

Paluch, K.J., Tajber, L., Corrigan, O.I., Healy, A.M., Investigation of physicochemical interactions of spray dried composites comprising polymer and chlorothiazide, chlorothiazide sodium or chlorothiazide potassium, APS Amorphous III proceedings, Nottingham, 2010, 2010 Poster, 2010

Tewes F, Tajber L, Corrigan OI, Ehrhardt C, Healy AM, Development and characterisation of soluble polymeric particles for pulmonary peptide delivery, European Journal of Pharmaceutical Sciences, 41, (2), 2010, p337 - 352 Journal Article, 2010 DOI TARA - Full Text

D'Arcy DM, Liu B, Bradley G, Healy AM, Corrigan OI, Hydrodynamic and species transfer simulations in the USP 4 dissolution apparatus: considerations for dissolution in a low velocity pulsing flow, Pharmaceutical Research, 27, (2), 2010, p246-58 Journal Article, 2010 DOI

Paluch KJ, Tajber L, McCabe T, O'Brien JE, Corrigan OI, Healy AM, Preparation and solid state characterisation of chlorothiazide sodium intermolecular self assembly suprastructure, European Journal of Pharmaceutical Sciences, 41, (5), 2010, p603 - 611 Journal Article, 2010 TARA - Full Text DOI

Tajber L, Corrigan DO, Corrigan OI, Healy AM, Spray drying of budesonide, formoterol fumarate and their composites-I. Physicochemical characterisation, International Journal of Pharmaceutics, 367, (1-2), 2009, p79 - 85 Journal Article, 2009 DOI

Dunne, MM, Ramtoola, Z, Corrigan, OI, Fluphenazine release from biodegradable microparticles: Characterization and modelling of release, JOURNAL OF MICROENCAPSULATION, 26, (5), 2009, p403 - 410 Journal Article, 2009

Corrigan OI, Li X, Quantifying drug release from PLGA nanoparticulates., European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 37, (3-4), 2009, p477-85 Journal Article, 2009 DOI

Paluch KJ, Tajber L, Corrigan OI, Healy AM, An investigation of the effect of spray drying from different solvents on the physicochemical properties of chlorothiazide and chlorothiazide sodium, AAPS Annual Meeting and Exposition, Los Angeles, USA, 8-12 November, 2009, 2009 Meeting Abstract, 2009

D'Arcy DM, Healy AM, Corrigan OI, Towards determining appropriate hydrodynamic conditions for in vitro in vivo correlations using computational fluid dynamics., European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 37, (3-4), 2009, p291-9 Journal Article, 2009 DOI

Tajber L, Corrigan OI, Healy AM, Spray drying of budesonide, formoterol fumarate and their composites-II. Statistical factorial design and in vitro deposition properties, International Journal of Pharmaceutics, 367, (1-2), 2009, p86 - 96 Journal Article, 2009 DOI

Ni Chearuil, Fiona, Corrigan, Owen I., Thermosensitivity and release from poly N-isopropylacrylamide-polylactide copolymers , International Journal of Pharmaceutics, 366, 2009, p21 - 30 Journal Article, 2009

Nolan LM, Tajber L, McDonald BF, Barham AS, Corrigan OI, Healy AM, Excipient-free nanoporous microparticles of budesonide for pulmonary delivery., European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 37, (5), 2009, p593-602 Journal Article, 2009 DOI

Li X, Radomski A, Corrigan OI, Tajber L, De Sousa Menezes F, Endter S, Medina C, Radomski MW, Platelet compatibility of PLGA, chitosan and PLGA-chitosan nanoparticles., Nanomedicine (London, England), 4, (7), 2009, p735-46 Journal Article, 2009 DOI

Paluch K, Tajber L, Healy AM, Corrigan OI, Comparison of the physico-chemical properties of spray dried chlorothiazide, chlorothiazide sodium and their PVP composite systems, 6th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Barcelona, Spain, 1-10, April 2008, 2008 Meeting Abstract, 2008

Coughlan, D.C., Corrigan, O.I.,, Release kinetics of benzoic acid and its sodium salt from a series of poly(N-isopropylacrylamide) matrices with various percentage crosslinking, Journal of Pharmaceutical Sciences, 97, (1), 2008, p318 - 330 Journal Article, 2008

Healy AM, McDonald BF, Tajber L, Corrigan OI, Characterisation of excipient-free nanoporous microparticles (NPMPs) of bendroflumethiazide , European Journal of Pharmaceutics and Biopharmaceutics , 69, (3), 2008, p1182 - 1186 Journal Article, 2008 DOI

Perez, P., Gallardo, A., Corrigan, O.I., Romaìn, J.S. , Thermosensitivity of N-isopropylacrylamide hydrogels cross-linked with degradable cross-linker , Journal of Biomaterials Science, Polymer Edition , 19, (6), 2008, p769 - 783 Journal Article, 2008

Katheri AK, Tajber L, Corrigan OI, Healy AM, Spray dried nanoporous microparticles of corticosteroids for dry powder oral inhalation, 6th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Barcelona, Spain, 1-10, April 2008, 2008 Meeting Abstract, 2008

Parojcic, J, Corrigan, O. I, Rationale for ibuprofen co-administration with antacids: Potential interaction mechanisms affecting drug absorption , European Journal of Pharmaceutics and Biopharmaceutics , 69, (2), 2008, p640 - 647 Journal Article, 2008

Tajber L, Crean B, Roberts CJ, Nolan L, Corrigan OI, Healy AM, Budesonide Nanoporous Microparticles (NPMPs) - in vitro Aerosolisation Properties and Atomic Force Microscopy (AFM), 35th Controlled Release Society Annual Meeting & Exposition, New York, USA, 12-16, July 2008, 2008 Meeting Abstract, 2008

Nolan, L.M.A., Corish, J., Corrigan, O.I., Fitzpatrick, D., Combined effect of iontophoretic and chemical enhancement on drug delivery - II. Transport accross human and murine skin , International Journal of Pharmaceutics, 341, (1-2), 2007, p114 - 124 Journal Article, 2007

C. Medina, MJ Santos-Martinez, A. Radomski, OI Corrigan and MW Radomski, Nanoparticles: pharmacological and toxicological significance, British Journal of Pharmacology, 150, (5), 2007, p552 - 558 Journal Article, 2007

D'Arcy, D.M., Corrigan, O.I., Healy, A.M., Use of Computational Fluid Dynamics (CFD) to investigate hydrodynamics involved in in vitro in vivo correlations (IVIVC) , EUFEPS/COST B 25 conference on Bioavailability (BA) and Bioequivalence (BE): Focus on physiological factors and variability., Athens, Greece, October, 2007 Poster, 2007

Parojcic J, Ibric S, Djuric Z, Jovanovic M, Corrigan OI, An investigation into the usefulness of generalised regression neural network analysis in the development of level A in vitro - in vivo correlation, European Journal of Pharmaceutical Sciences, 30, (3-4), 2007, p264 - 272 Journal Article, 2007

D'Arcy D.M., Corrigan, O.I., Healy, A.M., Investigating the hydrodynamics involved in early in vito in vivo correlations - computational fluid dynamics (CFD) simulations of hydrodynamics in the Levy beaker apparatus., PSWC 3rd World congress of the Board of Pharmaceutical Sciences of the FIP., Amsterdam, The Netherlands, April, 2007 Poster, 2007

Medina, C., Santos-Martinez, M.J., Radomski, A., Corrigan, O.I., Radomski, M.W., Nanoparticles: pharmacological and toxicological significance, British Journal of Pharmacology, 150, 2007 Review Article, 2007 DOI TARA - Full Text URL

Corrigan, D.O., Corrigan, O.I. and Healy, A.M, Physicochemical and in vitro deposition properties of salbutamol sulphate/ipratropium bromide and salbutamol sulphate/excipient spray dried mixtures for use in dry powder inhalers, International Journal of Pharmaceutics, 322, (1-2), 2006, p22 - 30 Journal Article, 2006

D'Arcy DM, Corrigan OI, Healy AM, Evaluation of hydrodynamics in the basket dissolution apparatus using computational fluid dynamics - Dissolution rate implications, European Journal of Pharmaceutical Sciences, 27, (2-3), 2006, p259 - 267 Journal Article, 2006

Lane ME, Brennan FS, Corrigan OI, Influence of post-emulsification drying processes on the microencapsulation of Human Serum Albumin, International Journal of Pharmaceutics, 307, (1), 2006, p16 - 22 Journal Article, 2006

Lewis G, Coughlan DC, Lane ME, Corrigan OI, Preparation and release of model drugs from thermally sensitive poly(N-isopropylacrylamide) based macrospheres, Journal of Microencapsulation, 23, (6), 2006, p677 - 685 Journal Article, 2006

Lane , M.E., Levis, K.A., Corrigan, O.I., Effect of intestinal fluid flux on ibuprofen absorption in the rat intestine, International Journal of Pharmaceutics, 309, (1-2), 2006, p60 - 66 Journal Article, 2006

Lane, M.L., Levis, K,A., McDonald, G.S.A., Corrigan, O.I., Comparative assessment of two indices of drug induced permeability changes in the perfused rat intestine, International Journal of Pharmaceutics, 312, (1-2), 2006, p196 - 199 Journal Article, 2006

Coughlan DC, Corrigan OI, Drug-polymer interactions and their effect on thermoresponsive poly(N-isopropylacrylamide) drug delivery systems, International Journal of Pharmaceutics, 313, 2006, p163 - 174 Journal Article, 2006

Killen BU, Corrigan OI, Effect of soluble filler on drug release from stearic acid based compacts, International Journal of Pharmaceutics, (316), 2006, p47 - 51 Journal Article, 2006

Lane ME, Corrigan OI, Paracellular and transcellular pathways facilitate insulin permeability in rat gut, Journal of Pharmacy and Pharmacology, 58, (2), 2006, p271 - 275 Journal Article, 2006

M.E. Lane, C. M. O'Driscoll,. and O. I. Corrigan, Quantitative estimation of the effects of bile salt surfactant systems on insulin stability and permeability in the rat intestine using a mass balance model, Journal of Pharmacy and Pharmacology, 57, 2005, p169 - 175 Journal Article, 2005

D'Arcy DM, Corrigan OI, Healy AM, Hydrodynamic simulation (computational fluid dynamics) of asymmetrically positioned tablets in the paddle dissolution apparatus: impact on dissolution rate and variability, Journal of Pharmacy and Pharmacology, 57, (10), 2005, p1243 - 1250 Journal Article, 2005

Lane ME, Brennan FS, Corrigan OI, Comparison of post-emulsion freeze drying or spray drying processes for the microencapsulation of plasmid DNA, Journal of Pharmacy and Pharmacology, 57, (7), 2005, p831 - 838 Journal Article, 2005

N. M. Prendeville M. E. Lane, C. Duffy, C. F. Murphy,, A. Flynn, O. I. Corrigan, Analysis of medicines returned by the general public to the Western Area Health Services Executive in 2004, Irish Pharmacy Journal, 83, (3), 2005, p101 - 104 Journal Article, 2005

Lidia Tajber, Owen I. Corrigan and Anne Marie Healy, Physicochemical evaluation of PVP-thiazide diuretic interactions in co-spray-dried composites-analysis of glass transition composition relationships, European Journal of Pharmaceutical Sciences, 24, (5), 2005, p553 - 563 Journal Article, 2005

Corrigan DO, Healy AM, Corrigan OI, Preparation and release of salbutamol from chitosan and chitosan co-spray dried compacts and multiparticulates, European Journal of Pharmaceutics and Biopharmaceutics, 62, (3), 2005, p295 - 395 Journal Article, 2005

DC Coughlan, FP Quilty, OI Corrigan, Effect of drug physicochemical properties on swelling/deswelling kinetics and pulsatile drug release from thermoresponsive poly(N-isopropylacrylamide) hydrogels, JOURNAL OF CONTROLLED RELEASE, 98, (1), 2004, p97 - 114 Journal Article, 2004

M.E. Lane, K. A. Levis, and O. I. Corrigan, Effect of ibuprofen on the rat intestinal permeability of GlySar' European Journal of Pharmaceutical Sciences, 23S, 2004, pS75 - S75 Journal Article, 2004

Crane M, Crane L, Healy AM, Corrigan OI, Gallagher KM, McCarthy LG, A Pohlhausen solution for the mass flux from a multi-layered compact in the USP drug dissolution apparatus, SIMULATION MODELLING PRACTICE AND THEORY, 12, (6), 2004, p397 - 411 Journal Article, 2004

M. E. Lane, K. A. Levis, O. I. Corrigan, Ketoprofen-induced permeability changes in the perfused rat intestine, AAPS Journal, S1:W4282, 2004 Journal Article, 2004

M. E. Lane, C. P. Landowski, P. B. Deasy, J. M. Quigley, G. L. Amidon, O. I. Corrigan, Synthesis and characterization of arginine derivatives of ibuprofen, AAPS Journal, 6, (S1:T2290), 2004 Journal Article, 2004

M. E. Lane, K. A. Levis, and O. I. Corrigan, Pharmacokinetics of amino acid derivatives of ibuprofen in the rat, European Journal of Pharmaceutical Sciences, 23S, 2004, pS70 - S71 Journal Article, 2004

M. Crane, N. Hurley, L. Crane, A.M. Healy, O.I. Corrigan, K.M. Gallagher and L.G. McCarthy, Simulation of the USP drug delivery problem using CFD: experimental, numerical and mathematical aspects, Simulation Modelling Practice and Theory, 12, 2, 2004, p147 - 158 Journal Article, 2004

Corrigan DO, Corrigan OI, Healy AM, Predicting the physical state of spray dried composites: salbutamol sulphate/lactose and salbutamol sulphate/polyethylene glycol co-spray dried systems, International Journal of Pharmaceutics, 273, (1-2), 2004, p171 - 182 Journal Article, 2004 DOI

McCarthy LG, Bradley G, Sexton JC, Corrigan OI, Healy AM., Computational Fluid Dynamics Modeling of the Paddle Dissolution Apparatus: Agitation Rate, Mixing Patterns, and Fluid Velocities, AAPS PharmSciTech., 5, (2), 2004 Journal Article, 2004

N. Kavanagh, OI Corrigan, Swelling and erosion properties of hydroxypropylmethylcellulose (Hypromellos) matrices - influence of agitation rate and dissolution medium composition, INTERNATIONAL JOURNAL OF PHARMACEUTICS, 279, (1-2), 2004, p141 - 152 Journal Article, 2004

M.E. Lane, N. Keating, and O.I. Corrigan, Patient satisfaction with pharmaceutical services at independent and chain pharmacies in the Republic of Ireland, Irish Pharmacy Journal, 82, (11), 2004, p486 - 492 Journal Article, 2004

M.E. Lane. K. A. Levis, K.A., O. I. Corrigan, Comparison of two methods for assessment of drug-induced intestinal permeability changes, European Journal of Pharmaceutical Sciences, 23S, 2004, pS52 - S52 Journal Article, 2004

DO Corrigan, AM Healy and OI Corrigan, The effect of spray drying solutions of bendroflumethiazide/polyethylene glycol on the physicochemical properties of the resultant materials, International Journal of Pharmaceutics, 262, (1-2), 2003, p125 - 137 Journal Article, 2003

McCarthy LG, Kosiol C, Healy AM, Bradley G, Sexton JC, Corrigan OI., Simulating the hydrodynamic conditions in the United States Pharmacopoeia paddle dissolution apparatus, AAPS PharmSciTech, 4, (2), 2003, pE22 Journal Article, 2003 URL

Owen I. Corrigan, Yvonne Devlin and Jackie Butler, Influence of dissolution medium buffer composition on ketoprofen release from ER products and in vitro-in vivo correlation, International Journal of Pharmaceutics, 254, (2), 2003, p147 - 154 Journal Article, 2003

Owen I. Corrigan and Majella E. Lane, An analysis of the use of the non-dispensing fee procedure by pharmacists in the General Medical Services (GMS) Scheme, Irish Pharmacy Journal, 81, 2003, p483 - 487 Journal Article, 2003

L. Weekes and O. I. Corrigan, Medication errors: A Hospital Pharmacy Survey, Irish Pharmacy Journal, 81, 2003, p284 - 288 Journal Article, 2003

OI Corrigan, RH Gubbins, CM O'Driscoll, Estimation of absorption parameters from the non-steady-state phase in the rat gut perfusion model, Journal of Pharmacy & Pharmacology, 55, (4), 2003, p487 - 493 Journal Article, 2003

Gubbins RH, O'Driscoll CM, Corrigan OI., The effects of casein on diclofenac release from hydroxypropylmethylcellulose (HPMC) compacts, International Journal of Pharmaceutics, 260, (1), 2003, p69 - 76 Journal Article, 2003

Karl A. Levis, Majella E. Lane and Owen I. Corrigan, Effect of buffer media composition on the solubility and effective permeability coefficient of ibuprofen, International Journal of Pharmaceutics, 253, (1-2), 2003, p49 - 59 Journal Article, 2003

R. Conroy and O. I. Corrigan, Community Pharmacists' Attitudes to ADR reporting, Irish Pharmacy Journal, 81, 2003, p354 - 363 Journal Article, 2003

Nolan LMA, Corish J, Corrigan OI., Iontophoretic and chemical enhancement of drug delivery - Part 1: Across artificial membranes, International Journal of Pharmaceutics, 257, (1-2), 2003, p41 - 55 Journal Article, 2003

A.Rosario Mollo and Owen I. Corrigan, Effect of poly-hydroxy aliphatic ester polymer type on amoxycillin release from cylindrical compacts, International Journal of Pharmaceutics, 268, (1-2), 2003, p71 - 79 Journal Article, 2003

Leane MM, Cumming I, Corrigan OI., The use of artificial neural networks for the selection of the most appropriate formulation and processing variables in order to predict the in vitro dissolution of sustained release minitablets, AAPS PharmSciTech, 4, (2), 2003, pE26 Journal Article, 2003 URL

J.A. Marley and O.I. Corrigan, Pharmacy students' views of Community Pharmacy in the aftermath of deregulation, Irish Pharmaceutical Union Review, 28, (3), 2003, p111 - 117 Journal Article, 2003

Corrigan D.O , Healy A. M, Corrigan O.I., The effect of spray drying solutions of polyethylene glycol (PEG) and lactose/PEG on their physicochemical properties, INT J PHARM, 235, (1-2), 2002, p193 - 205 Journal Article, 2002

Owen I. Corrigan, Abina M. Crean, Comparative physicochemical properties of hydrocortisone-PVP composites prepared using super critical carbon dioxide by the GAS anti-solvent recrystallization process, by coprecipitation and by spray drying, International Journal of Pharmaceutics, 245, (1-2), 2002, p75 - 82 Journal Article, 2002

Healy, A.M., McCarthy, L.G., Gallagher, K.M. and Corrigan, O.I., Sensitivity of dissolution rate to location in the paddle dissolution apparatus, J. Pharm. Pharmacology, 54, (3), 2002, p441 - 444 Journal Article, 2002

Mollo R & Corrigan O.I., An Investigation of the Mechanism of Release of the Amphoteric Drug Amoxycillin from Poly(d,l-Lactide-co-glycolide) Matrices, Pharmaceutical Development and Technology, 7, 2002, p333 - 343 Journal Article, 2002

Karen M. O'Connor and Owen I. Corrigan, The Effect Of A Basic Organic Excipient On The Dissolution Of Diclofenac Salts, Journal of Pharmaceutical Science, 91, (10), 2002, p2271 - 2281 Journal Article, 2002

A. Howlett, N. Arthur and Owen I. Corrigan, An Analysis of ADR Reporting by Pharmacists in Ireland, Irish Pharmacy Journal, 80, 2002, p519 - 527 Journal Article, 2002

MacNamee, B., Cunningham, P., Byrne, S., and Corrigan, O.I., The problem of bias in training data in regression problems in medical decision support, Artifficial Intelligence in Medicine, 24, 2002, p51 - 70 Journal Article, 2002

L. O'Dwyer, N. O'Brien and O.I. Corrigan, Changing patterns in Community Pharmacy employment in the Republic of Ireland, Irish Pharmacy Journal, 80, 2002, p371 - 379 Journal Article, 2002

Bronagh U. Killen and Owen I. Corrigan, Factors influencing drug release from stearic acid based compacts, International Journal of Pharmaceutics, 228, 2001, p189 - 198 Journal Article, 2001

O.I. Corrigan & B.A Heelan, Characterisation of drug release from diltiazem loaded polylactide microspheres prepared using sodium caseinate and whey protein as emulsifying agents, Journal of Microencapsulation, 18, (3), 2001, p335 - 345 Journal Article, 2001

Karen M. O'Connor and Owen I. Corrigan, Preparation and characterization of a range of diclofenac salts, International Journal of Pharmaceutics, 226, 2001, p163 - 179 Journal Article, 2001

Karen M. O'Connor and Owen I. Corrigan, Comparison of the physicochemical properties of the N-(2-hydroxyethyl) pyrrolidine, diethylamine and sodium salt forms of diclofenac, International Journal of Pharmaceutics, 222, 2001, p281 - 293 Journal Article, 2001

K.M. Gallagher & O.I. Corrigan, Mechanistic aspects of the release of levamisole hydrochloride from biodegradable polymers, Journal of Controlled Release, 69, 2000, p261 - 272 Journal Article, 2000

M. Dunne, O.I. Corrigan & Z. Ramtoola, Influence of dissolution conditions on the degradation properties of polylactide-co-glycolide particles, Biomaterials, 21, 2000, p1659 - 1668 Journal Article, 2000

O.I. Corrigan, The latent pharmacy manpower crisis, Irish Pharmacy Journal, 78, (1), 2000 Journal Article, 2000

F.O'Nia and O.I.Corrigan, Community Pharmacy Openings: Initial Impact of the new pharmacy contract, Irish Pharmacy Journal, 78, (10), 2000, p394 - 401 Journal Article, 2000

P.J. O'Dowd & O.I. Corrigan, Dissolution kinetics of three component non-disintegrating compacts: Theophylline, benzoic acid and salicylamide, International Journal of Pharmaceutics, 176, (2), 1999, p231 - 240 Journal Article, 1999

S. Byrne and O.I. Corrigan, An overview of pharmaceutical manpower and services in hospitals situated in the Republic of Ireland during 1998, Irish Pharmacy Journal, 77, (7), 1999, p220 - 215 Journal Article, 1999

O.M. Conaghey, J. Corish & O.I. Corrigan, Iontophoretically assisted in-vitro membrane transport of nicotine from a hydrogel containing ion exchange resins, International Journal of Pharmaceutics, 170, (2), 1998, p225 - 237 Journal Article, 1998

O. I. Corrigan, Preparation and evaluation of microspheres prepared from whey protein isolate, Journal of Microencapsulation, 15, (1), 1998, p93 - 105 Journal Article, 1998

O.I. Corrigan, Preparation and evaluation of microspheres prepared from whey protein isolate, Journal of Microencapsulation, 15, (1), 1998, p93 - 105 Journal Article, 1998

O.M. Conaghey, J. Corish & O.I. Corrigan, The release of nicotine from a hydrogel containing ion exchange resins, International Journal of Pharmaceutics, 170, (2), 1998, p215 - 224 Journal Article, 1998

M.T. Ledwidge & O.I. Corrigan, Effects of surface active characteristics and solid state forms on the pH solubility profiles of drug-salt systems, International Journal of Pharmaceutics, 174, (1-2), 1998, p187 - 200 Journal Article, 1998

A. Raoof, O.I. Corrigan, I. Cumming, J. Butler, J. Devane, Comparison of methodologies for evaluating regional intestinal permeability, Advances in Experimental Medicine & Biology, 423, 1997, p181 - 189 Journal Article, 1997

M.E. Lane, O.I. Corrigan and C.M. O'Driscoll, Absorption Enhancement Effects of Micellar Systems on a Range of Polyethylene glycols in the Rat Intestine, Journal of Controlled Release, 46, (1,2), 1997, p180 - 180 Journal Article, 1997

M.T. Ledwidge and O.I. Corrigan, Effects of environmental factors on the dehydration of diclofenac HEP dihydrate and theophylline monohydrate, International Journal of Pharmaceutics, 147, 1997, p41 - 49 Journal Article, 1997

M.G. Carr, J. Corish & O.I. Corrigan, Drug delivery from a liquid crystalline base across visking and human stratum corneum, International Journal of Pharmaceutics, 157, (1), 1997, p35 - 42 Journal Article, 1997

B.A. Heelan & O.I. Corrigan, In vitro analysis of the release of incorporated agents from sodium caseinate microspheres, J. Microencapsulation, 14, (1), 1997, p63 - 78 Journal Article, 1997

Corrigan, O.I., The Biopharmaceutic drug classification and drugs administered in extended release (ER) formulations, Advances in Experimental Medicine & Biology, 423, 1997, p111 - 128 Journal Article, 1997

A.M. Healy and O.I. Corrigan, The influence of excipient particle size, solubility and acid strength on the dissolution of an acidic drug from two-component compacts, International Journal of Pharmaceutics, 143, 1996, p211 - 221 Journal Article, 1996

M.T. Ledwidge, S.M. Draper, D.J. Wilcock and O.I. Corrigan, Physicochemical characterization of diclofenac N-(2-hydroxyethyl) pyrrolidine: anhydrate and dihydrate crystalline forms, Journal of Pharmaceutical Sciences, 85, 1996, p16 - 21 Journal Article, 1996

J. Corish and O.I. Corrigan, Passive Transdermal Device with Controlled Drug Delivery, 1996, United States Patent number 5,533,995 Patent, 1996

J.F. Fitzgerald, O.I. Corrigan, Investigation of the mechanisms governing the release of levamisole from poly-lactide-co-glycolide delivery systems, Journal of Controlled Release, 42, 1996, p125 - 132 Journal Article, 1996

M.E. Lane, C.M. O'Driscoll and O.I. Corrigan, The relationship between rat intestinal permeability and hydrophilic probe size, Pharmaceutical Research, 13, (10), 1996, p1554 - 1558 Journal Article, 1996

O.I. Corrigan, Thermal-Analysis of spray-dried products, Thermochim Acta, 248, 1995, p245 - 258 Journal Article, 1995

A.M. Healy, O.I. Corrigan and J.E.M. Allan, The effect of dissolution on the surface texture of model solid dosage forms as assessed by non-contact laser profilometry, Pharmaceutical Technology Europe, 7, (9), 1995, p14 - 22 Journal Article, 1995

M. Ring, P. Kennelly and O.I. Corrigan, An investigation of the cholelitholytic potential of N-alkyl pyrrolidone derivatives, Pharmacology (Life Science Advances), 14, 1995, p11 - 17 Journal Article, 1995

E.B. O'Reilly, O.I. Corrigan, Dissolution Rate of Cholesterol and Palmitic Acid Mixtures in Cholelitholytic Cosolvent Systems, Journal of Pharmaceutical Sciences, 84, (2), 1995, p203 - 207 Journal Article, 1995

M.J. Clancy, J. Corish and O.I. Corrigan, A Comparison of the Effects of Electrical Current and Penetration Enhancers on the Properties of Human Skin using Spectroscopic (FTIR) and Calorimetric (DSC) methods, International Journal of Pharmaceutics, 105, (1), 1994, p47 - 56 Journal Article, 1994

O.I. Corrigan, M.L. Wilkinson, J. Ryan, K. Harte and O.I. Corrrigan, The use of microtracers in a medicated premix to determine the presence of Tiamulin in final feed, Drug Devel. and Industrial Pharmacy, 20, 1994, p1503 - 1509 Journal Article, 1994

J.R. O'Reilly, O.I. Corrigan & C.M. O'Driscoll, The effect of simple micellar systems on the solubility and intestinal absorption of clofazimine (B663) in the anaethetised rat, International Journal of Pharmaceutics, 105, 1994, p137 - 146 Journal Article, 1994

L. M. A. Nolan, J. Corish and O.I. Corrigan, Electrical Properties of Human Stratum Corneum and Transdermal Drug Transport, J. Chem. Soc. Faraday Trans., 89, (15), 1993, p2839 - 2845 Journal Article, 1993

B.A. Heelan and O.I. Corrigan, A comparison of the use of dairy proteins and synthetic polymers as emulsifying agents in the production of pharmaceutical systems, Irish J. of Agriculture & Food Research, 32, 1993, p57 - 66 Journal Article, 1993

C.M. Fisher and O.I. Corrigan, Pharmacy Manpower 1991: An Analysis of Demographic Characteristics and Emigration Patterns, Irish Pharmacy Journal, 71, (1), 1993, p25 - 33 Journal Article, 1993

A.M. Rodriguez Bayon, J. Corish and O.I. Corrigan, In-vitro Passive and Iontophoretically Assisted Transport of Salbutamol Sulphate across Synthetic Membranes, Drug Development and Industrial Pharmacy, 19, (10), 1993, p1169 - 1181 Journal Article, 1993

K.M.S. Fahelelbom, R.F. Timoney and O.I. Corrigan, Micellar solubilization of clofazimine analogues in aqueous solutions of ionic and non-ionic surfactants, Pharmaceutical Research, 10, (4), 1993, p631 - 634 Journal Article, 1993

F.C. Millar and O.I. Corrigan, Dissolution mechanism of ibuprofen-casein compacts, Int. J. Pharm., 92, 1993, p97 - 104 Journal Article, 1993

A.M. Healy and O.I. Corrigan, Predicting the dissolution rate of ibuprofen-acidic excipient compressed mixtures in reactive media, International Journal of Pharmaceutics, 84, 1992, p164 - 173 Journal Article, 1992

D. Foley, J. Corish, and O.I. Corrigan, Iontophoretic delivery of drugs through membranes including human stratum corneum, Solid State Ionics, 53-56, 1992, p184 - 196 Journal Article, 1992

Y.B. Bannon, J. Corish, O.I. Corrigan and J.G. Masterson, Transdermal Drug Delivery Device, 1992, United States patent number 5,135,480 Patent, 1992

R. M. R. McGloughlin and O.I. Corrigan, Dissolution characteristics of benzoic acid-Tris mixtures, International Journal of Pharmaceutics, 82, 1992, p135 - 143 Journal Article, 1992

Z. Ramtoola, O.I. Corrigan and C.J. Barrett, Release kinetics of fluphenazine from biodegradable microspheres, J. Microencapsulation, 9, (4), 1992, p415 - 423 Journal Article, 1992

Fisher CM, Henman MC, Corrigan OI, A study of community pharmacy practice 1, Journal of Social and Administrative Pharmacy, 8, (1), 1991, p15 - 24 Journal Article, 1991 TARA - Full Text

O.I. Corrigan, Co-solvent systems in Dissolution Testing: Theoretical considerations, Drug Devel. Ind. Pharm., 18, (5), 1991, p695 - 708 Journal Article, 1991

C.M. Fisher, M.C. Henman and O.I. Corrigan, A study of community pharmacy practice, 1: Pharmacists work patterns, J. Social and Admin. Pharm., 8, 1991, p15 - 24 Journal Article, 1991 TARA - Full Text

Z. Ramtoola, O.I. Corrigan, and E. Bourke, Characterization of biodegradable microspheres containing dehydro-iso-androsterone, Drug Devel. Ind. Pharm., 17, (13), 1991, p1857 - 1873 Journal Article, 1991

C.M. Fisher, M.C. Henman and O.I. Corrigan, A study of community pharmacy practice, 2: Prescription Dispensing, Journal of Social and Administrative Pharmacy, 8, (2), 1991, p65 - 68 Journal Article, 1991 TARA - Full Text

C.M. Fisher, M.C. Henman and O.I. Corrigan, A study of pharmacy practice. Non-prescribed medicines sales and counselling 3, Journal of Social and Administrative Pharmacy, 8, (2), 1991, p69 - 75 Journal Article, 1991 TARA - Full Text

F.C. Millar and O.I. Corrigan, Influence of casein on the dissolution rate of hydrochlorothiazide and chlorothiazide, Drug Devel. Ind. Pharm., 17, (12), 1991, p1593 - 1607 Journal Article, 1991

C.M. Fisher, O.I. Corrigan and M.C. Henman, The Quality of Pharmaceutical Service in Community Pharmacies, J. Soc. and Admin., 8, 1991, p175 - 179 Journal Article, 1991

J. Corish and O.I. Corrigan, Transdermal Diffusion of Drug Molecules, J. Chem. Soc. Faraday Trans., 86, (8), 1990, p1317 - 1321 Journal Article, 1990

O.I. Corrigan, Temperature dependence and thermodynamics of partitioning of clofazimine analogues in the n-octanol/water system, International Journal of Pharmaceutics, 58, 1990, p107 - 113 Journal Article, 1990

J. Corish, O.I. Corrigan and D. Foley, Iontophoretic Transport of Analgesics, Chemica Oggi, 6, 1989, p17 - 22 Journal Article, 1989

Y.B. Bannon, J. Corish, O.I. Corrigan, J. Devane, M. Kavanagh and S. Mulligan, Transdermal Delivery of Nicotine in Normal Human Volunteers: A Single Dose and Multiple Dose Study, European Journal Clinical Pharmacology, 37, 1989, p285 - 290 Journal Article, 1989

Z. Ramtoola and O.I. Corrigan, Influence of the Buffering Capacity of the Medium on the Dissolution of Drug-Excipient Mixtures, Drug Devel. Ind. Pharm., 15, (14-16), 1989, p2359 - 2374 Journal Article, 1989

Y.B. Bannon, J. Corish, O.I. Corrigan and J.G. Masterson, Iontophoretically Induced Transdermal Delivery of Salbutamol, Drug Devel. Ind. Pharm., 14, 1988, p2151 - 2166 Journal Article, 1988

Z. Ramtoola and O.I. Corrigan, Effect of Agitation Intensity on the Dissolution Rate of Indomethacin and Indomethacin-Citric Acid Compressed Discs, Drug Devel. Ind. Pharm., 14, 1988, p2241 - 2254 Journal Article, 1988

Z. Ramtoola and O.I. Corrigan, Dissolution Characteristics of Benzoic Acid and Salicylic Acid Mixtures in Reactive Media, Drug Devel. Ind. Pharm., I3, 1987, p1703 - 1720 Journal Article, 1987

Y.B. Bannon, J. Corish, O.I. Corrigan, E. Geoghegan and J.G. Masterson, Method for the treatment of withdrawal symptoms associated with smoking cessation and preparations for use in said method, 1987, United States Patent number : 4,946,853 Patent, 1987

Y.B. Bannon, J. Corish and O.I. Corrigan, Iontophoretic transport of model compounds from a gel matrix across a cellophane membrane, Drug Devel. Ind. Pharm., 13, (14), 1987, p2617 - 2630 Journal Article, 1987

C.M. Fisher, M.C. Henman and O.I. Corrigan, Employment patterns of male and female pharmacy graduates, J. Social and Admin. Pharm., 5, 1987, p1 - 11 Journal Article, 1987

M.C. Ferrando, M.C. Henman and O.I. Corrigan, Impact of a nationwide limited prescribing list, Drug Intell. & Clin. Pharm., 21, 1987, p653 - 657 Journal Article, 1987

O.I. Corrigan, Retardation of polymeric carrier dissolution by dispersed drugs: factors influencing the dissolution of solid dispersions containing polyethylene glycols, Drug Devel. Ind. Pharm., 12, 1986, p1777 - 1793 Journal Article, 1986

D.H. Doff, F.L. Brownen and O.I. Corrigan, Determination of alpha impurities in the beta polymorph of inosine using infra-red spectroscopy and x-ray powder diffraction, The Analyst, 111, 1986, p179 - 182 Journal Article, 1986

S.C. Mulligan and O.I. Corrigan, Mechanism of dissolution of cholesterol-calcium bilirubinate compressed discs in mono-octanoin, J. Pharm. Pharmacol, 38, 1986, p638 - 642 Journal Article, 1986

O.I. Corrigan, Mechanisms of dissolution of fast release solid dispersions, Drug Devel. Ind. Pharm., 11, 1985, p697 - 724 Journal Article, 1985

O.I. Corrigan, E.M. Holohan and M.R. Reilly, Physicochemical properties of indomethacin and related compounds co-spray dried with polyvinylpyrrolidone, Drug Devel. Ind. Pharm., ll, 1985, p677 - 696 Journal Article, 1985

O.I. Corrigan and E.M. Holohan, Amorphous spray-dried hydroflumethiazide polyvinylpyrrolidone systems:physicochemical properties, J. Pharm. Pharmac., 36, 1984, p217 - 221 Journal Article, 1984

O.I. Corrigan, E.M. Holohan and K. Sabra, Amorphous forms of thiazide diuretics prepared by spray-drying, International Journal of Pharmaceutics, 18, 1984, p195 - 200 Journal Article, 1984

S.C. Mulligan, P. Kennelly and O.I. Corrigan, The composition of gallstones from Irish patients, I. J. Med. Sci., 153, 1984, p106 - 111 Journal Article, 1984

P.B. Bottini, J.G. Devane and O.I. Corrigan, Sustained absorption does not necessarily reduce the systemic availability of propanolol, Drug Devel. Ind. Pharm, 10, 1984, p1757 - 1775 Journal Article, 1984

O.I. Corrigan, Drug prescribing in an orthopaedic hospital with particular reference to night sedative consumption, I. Med., J., 76, 1983, p21 - 24 Journal Article, 1983

K.M. O'Driscoll and O.I. Corrigan, The influence of perfusion rate on salicylate absorption in the rat, J. Pharm. Pharmac., 35, 1983, p814 - 815 Journal Article, 1983

O.I. Corrigan, K. Sabra and E.M. Holohan, Physicochemical properties of spray-dried drugs: phenobarbitone and hydroflumethiazide, Devel. Ind. Pharm., 9, (1&2), 1983, p1 - 20 Journal Article, 1983

K.M. O'Driscoll and O.I. Corrigan, Chlorothiazide - polyvinylpyrrolidone (PVP) interactions: influence on membrane permeation (everted rat intestine) and dissolution, Drug Devel. Ind. Pharm., 8, (4), 1982, p547 - 564 Journal Article, 1982

O.I. Corrigan and C.T. Stanley, Mechanism of drug dissolution rate enhancement from betacyclodextrin-drug systems, J. Pharm. Pharmac., 34, (2), 1982, p621 - 626 Journal Article, 1982

D.E. Panoz and O.I. Corrigan, Medicaments with a high degree of solubility and method for their production, 1982, US Patent No. 4,610,875 Patent, 1982

O.I. Corrigan and C.T. Stanley, Dissolution properties of phenobarbitone - beta-cyclodextrin systems, Pharm. Acta Helvetiae, 56, 1981, p204 - 208 Journal Article, 1981

C.C. Su, M.H. Alkan, J.Y. Park, O.I. Corrigan, W.I. Higuchi, A.F. Hofmann and R.G. Danzinger, Mesophase formation during in vitro cholesterol gallstone dissolution : A specific effect of ursodeoxycholic acid, J. Pharm. Sci., 70, 1981, p713 - 715 Journal Article, 1981

O.I. Corrigan, M.A. Farvar and W.I. Higuchi, Drug membrane transport enhancement using high energy drug polyvinylpyrrolidone (PVP) coprecipitates, International Journal of Pharmaceutics, 5, 1980, p229 - 238 Journal Article, 1980

O.I. Corrigan and Katherine M. O'Driscoll, The effect of dosage on the bioavailability of chlorothiazide administered in solution, J. Pharm. Pharmac., 32, 1980, p547 - 549 Journal Article, 1980

O.I. Corrigan, C.C. Su, W.I. Higuchi and A.F. Hofmann, Mesophase formation during cholesterol dissolution in ursodeoxychholate-lecithin solutions: New mechanism for gallstone dissolution in humans, J. Pharm. Sci., 69, 1980, p869 - 871 Journal Article, 1980

O.I. Corrigan, I. Med. J., An analysis of the prescribing of certain hypnotics, sedatives and minor tranquillizers among General Medical Services patients, 72, 1980, p295 - 299 Journal Article, 1980

O.I. Corrigan, Employment Trends in Community Pharmacy in the Republic of Ireland, IPU Review, 1980, p266 - 268 Journal Article, 1980

O.I. Corrigan, C.A. Murphy and R.F. Timoney, Dissolution properties of polyethylene glycols and polyethylene glycol-drug systems, International Journal of Pharmaceutics, 4, 1979, p67 - 74 Journal Article, 1979

O.I. Corrigan and R.F. Timoney, Towards standardizing agitation conditions in the beaker dissolution method, International Journal of Pharmaceutics, 1, 1978, p299 - 302 Journal Article, 1978

O.I. Corrigan, Some aspects of Pharmaceutical Manpower in the Republic of Ireland, IPU Review, 3, 1978, p4 - 7 Journal Article, 1978

O.I. Corrigan, R.F. Timoney and M.J. Whelan, The influence of polyvinylpyrrolidone on the dissolution and bioavailability of hydrochlorothiazide, J. Pharm. Pharmac., 28, 1976, p703 - 706 Journal Article, 1976

O.I. Corrigan and R.F. Timoney, The influence of polyethylene glycols on the dissolution properties of hydroflumethiazide, Pharm. Acta Helvetiae, 51, 1976, p268 - 271 Journal Article, 1976

O.I. Corrigan and R.F. Timoney, The influence of polyvinylpyrrolidone on the dissolution properties of hydroflumethiazide, J. Pharm. Pharmac., 27, 1975, p759 - 764 Journal Article, 1975

O.I. Corrigan and R.F. Timoney., Some aspects of the influence of formulation on the bioavailability of drugs from solid dosage forms, I.J. Med. Sc., 143, (4), 1974, p197 - 207 Journal Article, 1974

O.I. Corrigan and R.F. Timoney, Anomalous behaviour of some hydroflumethiazide crystal samples, J. Pharm. Pharmac., 26, 1974, p838 - 840 Journal Article, 1974

O.I. Corrigan and R.F. Timoney, In vitro evaluation of the physiological availability of aspirin tablets, I.J. Med. Sc., Eighth series, 3, (1), 1970, p15 - 21 Journal Article, 1970

O.I. Corrigan and R.F. Timoney, Dissolution properties of digoxin tablets marketed in the Republic of Ireland, I. Med. J., 69, (3), 1970, p60 Journal Article, 1970

Non-Peer-Reviewed Publications

M.E. Malone, C. Gowing, M. Barry, E. Deasy, P.V. Kavanagh, O.I. Corrigan, D.M. D'Arcy, M. Donnelly, Do plasma protein levels influence the volume of distribution of Amphotericin B Lipid Complex?, Intensive Care Society of Ireland Annual Scientific Meeting, Dublin, Ireland, June 2012, 2012 Poster, 2012

Malone M.E., Gowing C., Barry M., Deasy E., Kavanagh P.V., Corrigan O.I., D'Arcy D.M., Donnelly M. Clinical pharmacokinetics research group, Pharmacokinetics of amphotericin B lipid complex in critically ill patients on and off continuous venovenous heeamodiafiltration, All Ireland Schools of Pharmacy and Pharmaceutical Sciences Conference, Cork, 2012, 2012 Poster, 2012

M.E. Malone, C. Gowing, M. Barry, E. Deasy, P.V. Kavanagh, O.I. Corrigan, D.M. D'Arcy, M. Donnelly, Determination of pharmacokinetic parameters of amphotericin B in critically ill patients during continuous venovenous haemodiafiltration-analytical methodology and clinical trial design, All Ireland Schools of Pharmacy and Pharmaceutical Sciences Conference, Belfast, Northern Ireland, April 2010, 2010 Oral Presentation, 2010

Paluch, K.J., Tajber, L., Corrigan, O.I., Healy, A.M., Solid state characterisation of novel active pharmaceutical ingredients: co-crystal of (R,S) salbutamol mono-adipate and (R,S) salbutamol hemisuccinate, Solid State Pharmaceutical Cluster Meeting, Limerick, 2010, 2010 Poster, 2010

Paluch K, Tajber L, Corrigan OI, Healy AM, An investigation of the effect of spray drying from different solvents on the physicochemical properties of chlorothiazide and chlorothiazide sodium, IRCSET Symposium Innovation fuelling the Smart Society, Dublin, 2009, 2009 Poster, 2009

Paluch K., Tajber L., Healy A.M., Corrigan O. , Impact of solvent variable on chlorothiazide and chlorothiazide sodium physico-chemical properties, processed by spray drying, All Ireland Schools of Pharmacy 31st Research Seminar, Dublin, 2009, 2009 Meeting Abstract, 2009

Paluch, K., Tajber, L., Healy, A.M. and Corrigan, O.I., Solid-state characteristics of spray dried chlorothiazide, chlorothiazide-PVP composites, sodium chlorothiazide and sodium chlorothiazide-PVP composites, All Ireland Schools of Pharmacy 30th Research Seminar, Cork, 2008, 2008 Meeting Abstract, 2008

"Salt Forms: Pharmaceutical Aspects" , James Swarbrick, James C. Boylan (Eds.), , Encyclopaedia of Pharmaceutical Technology , 2, New York, Marcel Dekker, Inc., 2004, [O.I. Corrigan] Item in dictionary or encyclopaedia, etc, 2004

Salt Forms: Pharmaceutical Aspects 1-13, James Swarbrick, James C. Boylan, Encyclopaedia of Pharmaceutical Technology, New York, Marcel Dekker Inc., 2004, [OI Corrigan] Item in dictionary or encyclopaedia, etc, 2004

Surfactants in pharmaceutical products and systems, James Swarbrick, James C. Boylan, Encyclopaedia of Pharmaceutical Technology, 2nd Ed, New York, Marcel Dekker, Inc., 2002, pp2639 - 2653, [O.I. Corrigan, A.M. Healy] Item in dictionary or encyclopaedia, etc, 2002

Surfactants in pharmaceutical products and systems, Swarbrick, J. and Boylan, J.C., Encyclopedia of Pharmaceutical Technology, 2nd Edition, Marcel Dekker, 2002, pp2639 - 2653, [O.I. Corrigan and A.M. Healy] Item in dictionary or encyclopaedia, etc, 2002

N.J.Hurley, L. Crane, A.M.Healy, O.I.Corrigan, K.M.Gallagher and L.G.McCarthy, Modelling drug delivery systems using finite element analysis, The 2nd Conference on Modelling and Simulation in Biology, Medicine and Biomedical Engineering , incorporated in the 4th International EUROSIM Congress, Aula Conference Centre, Delft, The Netherlands, June 26-29, 2001 Conference Paper, 2001

S.Byrne, P. Cunningham, A. Barry, I. Graham, T. Delaney and O.I. Corrigan, Using Neural Nets for Decision Support in Prescription and outcome Prediction in Anticoagulation Drug Therapy, Proceedings of 5th International Workshop on Intelligent Data Analysis in Medicine and Pharmacology at 14th European Conference on Artificial Intelligence, Berlin, Germany, August, edited by N. Lavrac, S. Miksch and B. Kavsek , 2000, pp9 - 12 Conference Paper, 2000

S.Byrne, , A. Barry , P. Cunningham, I. Graham, T. Delaney and O.I. Corrigan, Do Artificial Neural Networks have a place in Warfarin Therapy?, Pharmacy World Congress 2000, 60th International Congress of FIP Abstracts, Vienna, Austria, August, 2000 Meeting Abstract, 2000

Carbenoxolone Sodium in, editor(s)H.G. Brittain , Analytical profiles of drug substances and excipients, 1996, pp1 - 44, [S. Pindado, O.I. Corrigan and C.M. O'Driscoll] Book Chapter, 1996

Surfactants in pharmaceutical products and systems, James Swarbrick, James C. Boylan, Encyclopaedia of Pharmaceutical Technology, New York, Marcel Dekker, Inc., 1996, [O.I. Corrigan, A.M. Healy] Item in dictionary or encyclopaedia, etc, 1996

Drug-polyvinylpyrrolidone coprecipitates in, editor(s)E.W.Smith and H.I. Maibach , Percutaneous penetration enhancers, CRC Press, 1995, [O. I. Corrigan] Book Chapter, 1995

Drug-polyvinylpyrrolidone coprecipitates in, editor(s)E.W.Smith and H.I. Maibach , Percutaneous penetration enhancers, CRC Press, 1995, pp221 - 242, [O. I. Corrigan] Book Chapter, 1995

V. Freeman, O.I. Corrigan & Z. Ramtoola, Poly-DL-Lactide Microspheres containing Diltiazem Base: Morphology and Release Properties, Proceedings of World Congress of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan, September, 1993 Conference Paper, 1993

L.M. Clarke & O.I. Corrigan, Dissolution Studies of Vaterite in Aqueous Media containing Complexing Agents, Proceedings of World Congress of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan, September, 1993, pp78 - 78 Conference Paper, 1993

O.I. Corrigan, Solid Dispersed System for Drug Delivery, Proceedings of Pharmaceutical Product Development Symposium, Gifu, Japan, 1993, pp27 - 35 Conference Paper, 1993

O.I. Corrigan and J.F. Fitzgerald, The Mechanisms of drug release from poly-D, L-lactide-co-glycolide co-evaporate discs containing levamisole base and levamisole hydrochloride, Proceedings of the Monte Verita Conference on Biocompatible Material Systems, Switzerland, 1993, ppII-2 Conference Paper, 1993

Mechanisms governing drug release from poly-alpha-hydroxy aliphatic esters. Diltiazem base release from poly-lactide-co-glycolide delivery systems in, "Polymeric Delivery Systems - Properties and Applications" , ACS Symposium Series 520, American Chemical Society, 1993, pp313 , [J.F. Fitzgerald and O.I. Corrigan] Book Chapter, 1993

A.B. Brady, J. Corish and O.I. Corrigan, Passive and electrically assisted transdermal delivery of Nicotine - in vitro studies using hairless mouse skin and human stratum corneum, Proceedings of 19th International Symposium on Controlled Release of Bioactive Materials, USA, July, 1992, pp489 - 490 Conference Paper, 1992

The in vivo modification of the transdermal transport of nicotine using iontophoresis in, Prediction of Percutaneous Penetration, vol. 2, 1992, pp410 - 419, [Y.B. Bannon, A.B. Brady J. Corish, O.I. Corrigan, D. Foley, M. Martin] Book Chapter, 1992

Clofazimine in, editor(s)Florey, K. , 'Analytical Profiles of Drug Substances and Excipients. Vol 21, Academic Press, 1992, pp75 - 108, [K.M. O'Driscoll and O.I. Corrigan] Book Chapter, 1992

V. Hester, O.I. Corrigan, Z. Ramtoola, Characterization of Biodegradable Microspheres of Reducing Size Containing Diltiazem Hydrochloride, Proceedings 6th International Pharmaceutical Technology Symposium, Turkey, September, 1992, pp54 Conference Paper, 1992

C.M. Fisher and O.I. Corrigan, Pharmacy Manpower 1991: An analysis of Demographic Characteristics and Emigration Patterns, The College of Pharmacy Practice, 37 Northumberland Road, Dublin 2, October 1992, 1992 Report, 1992

O.I. Corrigan, R. Gubbins, and C.M. O'Driscoll, Estimation of absorption parameters from the non-steady-state phase of a rat gut perfusion model, Proceedings of 19th International Symposium on Controlled Release of Bioactive Materials, USA, July, 1992, pp279 - 280 Conference Paper, 1992

B.A. Heelan and O.I. Corrigan, The Use of Turbidity Measurements for In-Process Control in Polylactide Microsphere Manufacture, Proceedings of 8th International Symposium on Microencapsulation, Dublin, September, 1992, pp39 Conference Paper, 1992

Owen I. Corrigan and J.P. O'Leary, Release of Benzoic Acid and its salts from Polyethylene gelled paraffin bases, Proceedings of 19th International Symposium on Controlled Release of Bioactive Materials, USA, July, 1992, pp429 - 430 Conference Paper, 1992

M. O'Sullivan, J.M. Clancy, J. Roche and O.I. Corrigan, Controlled Delivery of Oestradiol from silastic implants: in vitro and in vivo evaluation, European Journal of Metabolism and Pharmacokinetics, Proceedings of the 4th European congress of biopharmaceutics and pharmacokinetics, (III), 1991, pp478 - 482 Conference Paper, 1991

The in-vivo modification of the transdermal transport of nicotine using iontophoresis in, Prediction of Percutaneous Penetration, Methods Measurements Modelling, 1991, pp410 - 419, [Y.B. Bannon, A. B. Brady, J.Corish, O.I. Corrigan, D. Foley and M. Martin] Book Chapter, 1991

Passive and electrically assisted transdermal delivery of es-amino-8-D-argininevasopressin in vitro from a gel matrix in, Prediction of Percutaneous Penetration, Methods Measurements Modelling, 1991, pp401 - 409, [A.B. Brady, J.Corish and O.I. Corrigan] Book Chapter, 1991

The effect of iontophoresis on the electrical and transport properties of human epidermal tissue in, Prediction of Percutaneous Penetration, Methods Measurement Modelling, Volume 2, 1991, pp420 - 431, [D. Foley, J. Corish and O.I. Corrigan] Book Chapter, 1991

K.M. O'Driscoll, J.R. O'Reilly, and O.I. Corrigan, A comparison of the effects of synthetic and naturally occuring surfactants on the solubility and absorption of clofazimine (B 663), European Journal of Drug Metabolism and Pharmacokinetics, Proceedings of the 4th European congress of biopharmaceutics and pharmacokinetics, (III), 1991, pp116 - 119 Conference Paper, 1991

K.M. O'Driscoll, C. Osbourne and O.I. Corrigan, Effect of beta-Cyclodextrin on the membrane transport of benzoic acid and phenobarbitone through silastic membrane, Minutes of the Fifth International Symposium on Cyclodextrins, edited by D. Duchene , 1990, pp431 - 433 Conference Paper, 1990

O.I. Corrigan, Temperature dependence and thermodynamics of partitioning of clofazimine analogues in the n-octanol/water system, International Journal of Pharmaceutics, 58, 1990, p107 - 113 Journal Article, 1990

D. Foley, J. Corish & O.I. Corrigan, The use of complex impedance to examine the effect of passive and iontophoretic transdermal drug transport through excised human epidermal tissue, Proceedings of the 17th International Symposium on Controlled Release of Bioactive Materials, 1990, pp427 - 428 Conference Paper, 1990

Z. Ramtoola, O.I. Corrigan, and E. Bourke, Sustained release of fluphenazine from biodegradable microspheres, Proceedings of the 17th International Symposium on Controlled Release of Bioactive Materials, 1990, pp287 - 288 Conference Paper, 1990

The effect of glycerol on the transdermal delivery of nicotine in, editor(s)R.C.Scott, R.H. Guy and J. Hadgraft , Prediction of Percutaneous Penetration, London, IBC Tech. Services, 1990, pp290 - 298, [Y.B. Bannon, J. Corish, O.I. Corrigan and J.Devane] Book Chapter, 1990

The iontophoretic transdermal delivery of morphine hydrochloride and other salts across exised human stratum corneum in, editor(s)R.C. Scott, R.H. Guy and J. Hadgraft , Prediction of Percutaneous Penetration, London, IBC Tech. Services, 1990, pp302 - 307, [ J. Corish, O.I. Corrigan and D. Foley] Book Chapter, 1990

K.M.S. Fahelelbom, R.F. Timoney, J.M. Quigley and O.I. Corrigan, Thermodynamics of the distribution and interfacial transfer kinetics of antimicrobial iminophenazones in a two-phase system of n-octanol /aqueous buffer, Proc. Royal Irish Academy, 89b, 1989, pp287 - 298 Conference Paper, 1989

Y.B. Bannon, J. Corish and O.I. Corrigan, Iontophoretically enhanced drug absorption across human stratum corneum from a gel matrix, Biopharmaceutics, Proceedings of the Third European Congress of Biopharmaceutics and Pharmacokinetics, L'Universite de Clermont Ferrand, France, edited by J.M. Aiche and J. Hirtz , 1, 1987, pp301 - 309 Conference Paper, 1987

Retardation of polymeric carrier dissolution by dispersed drugs in, editor(s)M.H. Rubenstein , Pharmaceutical Technology: Controlled Drug Release, Vol.1, Ellis Harwood Ltd, 1987, pp88 - 98, [O.I. Corrigan] Book Chapter, 1987

Corrigan OI, Henman MC, Hurley L. , Corrigan OI, Henman MC, Hurley L. Computers in Community Pharmacy: a survey., Irish Pharmaceutical Union Review, 11, 1986, p244 - 245 Journal Article, 1986

A. Dunne, O.I. Corrigan, P.B. Bottini and E.J. Geoghegan, Bioavailability considerations in the design of controlled absorption ibuprofen formulations: an absorption window model, Biopharmaceutics, Proceedings of Second European Congress of Biopharmaceutics and Pharmacokinetics, 1, 1984, pp421 - 427 Conference Paper, 1984

Development of a Controlled Absorption Quinidine Drug Delivery System in, editor(s)T.J. Roseman and S.Z. Mansdorf , Controlled Release Delivery Systems, New York and Basle, Marcel Dekker, Inc., 1983, pp163 - 167, [O.I. Corrigan, A. Dunne, H. Mc Laughlin, E. Geoghegan, C.A. Killian and D.E. Panoz] Book Chapter, 1983

K.M. O'Driscoll and O.I. Corrigan, Influence of polyvinylpyrrolidone (PVP) on the membrane (everted rat intestine) transport of chlorothiazide, Proceedings of the First European Congress of Biopharmaceutics and Pharmacokinetics, Paris, 1, Biopharmaceutics, Technique et Documentation, 1981, pp71 - 79 Conference Paper, 1981

Research Expertise

Description

Pharmaceutics and Pharmaceutical Technology.

Projects

  • Title
    • Novel microparticles for drug delivery
  • Title
    • 'Smart' polymers for drug delivery
  • Title
    • - Clinical pharmacokinetics of drugs in ICU patients
  • Title
    • Modelling mass transfer in pharmaceutical systems using HPC

Keywords

Antiinflammatory drugs; Biopharmaceutical aspects of drug delivery systems; Composite materials; Computer modelling of pharmaceutical systems; Crystal engineering; Drug delivery technology, gene delivery; Drug release mechanisms; Drug transport mechanisms; Drug utilisation and epidemiology; Formulation and evaluation of vaccines; Matrix tabletts, sustained drug delivery; Mechanisms of dissolution; Mechanisms of drug release from solid dosage forms; Nanotechnology; Pharmaceutical care; Pharmaceutical products; Physiological and physiochemical barriers to drug absorption; Polymer technology, biopolymers; Polymers; Quality, regulatory and GMP areas of pharmaceutical chemistry; Transdermal products

Recognition

Representations

Examiner in Forensic Pharmacy for the Pharmaceutical . Society of Ireland under the Pharmacy Acts Ireland 1975 - 1985

Appointed by the Minister for Health to the Human Medicines Advisory Committee of the Irish Medicines Board 1996-2002

Appointed by the Minister for Health to the Health Research Board 2004-Present

Consultant in Biopharmaceutics and Member of Research and Development Committee, Elan Corporation Ltd., Athlone, Ireland. 1977 - 1984

Founder editor of monthly "Journal of Irish Pharmaceutical Union". (I.P.U. Review). 1977 -1979

Member of Scientific Research Committee, Elan Pharmaceutical Research Corporation, Georgia, U.S.A. 1981 - 1984

Member of Scientific Committee, Elan Corporation plc, Athlone, Ireland. 1984 - 1988

Consultant in Biopharmaceutics to Elan Corporation plc. 1988 - 2000

Consultant in Transdermal Drug Delivery to Elan Corporation plc. 1991 - 1994

Member of the Editorial Advisory Board of 'Pharmaceutical Technology Europe', Astra Publishing Corp. 1989-2003

Member of International Editorial Advisory Board of The Encyclopaedia of Pharmaceutical Technology. 2003-Present

Consultant to Antigen Pharmaceuticals Ltd. 1990 -2000

Consultant to Elan Pharmaceutical Technologies 1994 - Present

Awards and Honours

Elected a Fellow of the Royal Academy of Medicine in Ireland. 1982

Elected a Fellow of Trinity College 1988

Elected Fellow of the Pharmaceutical Society of Ireland 1993

Memberships

European Federation for Pharmaceutical Sciences(EUFEPS), American Association of Pharmaceutical Scientists (AAPS), The Controlled Release Society(CRS), Royal Academy of Medicine in Ireland(RAMI), Pharmaceutical Society of Ireland(PSI), Irish Pharmaceutical Union(IPU).