Dr. Cormac Kennedy
Senior Lecturer Consultant, School Office - Medicine
Senior Lecturer Consultant, Pharmacology & Therapeutics
Biography
Dr Cormac Kennedy is currently a Consultant Clinical Pharmacologist and Physician at St James Hospital as well as a Clinical Senior Lecturer at Trinity College Dublin. His experience gives him a perspective of the journey of medicines from the bench to the bedside including the pharmaceutical, regulatory, economic, policy and clinical contexts.
Cormac is a graduate of UCD Medical School and the School of Pharmacy Trinity College. He completed a PhD at the Royal College of Surgeons in Ireland, the product of which was subsequently patented.
He received a HSE-NDTP Management and Leadership Scholarship to undertake a Masters in Health Economics, Outcomes and Management at the London School of Economics and was awarded a Distinction. He is undertaking a Masters in Clinical Trials at Oxford University.
He chaired the Trainee Committee of the Royal College of Physicians in Ireland. He was a member of the RCPI Council, its highest body, representing nearly 2,000 Irish medical trainees.
His clinical interests include the specialist treatment of hypertension and lipid disorders and he has presented internationally and published in these areas. His other research interests are across a spectrum of areas related to medicines including pharmacoepidemiology, pharmacoeconomics and appropriate drug usage.
Publications and Further Research Outputs
Peer-Reviewed Publications
Harbison J, McCormack J, Brych O, Collins R, O'Connell N, Randles M, Kennedy C, Kelly PJ, Cassidy T., Changes in Anticoagulation Practice in Subjects Admitted with Stroke Associated with Atrial Fibrillation, following introduction of Direct Oral Anticoagulants over 2013-2021. , International journal of stroke : official journal of the International Stroke Society, 2023, p17474930231206680
R Malone, C Kennedy, Restarting statins in a specialist lipid clinic setting, European Journal of Preventive Cardiology, 30, (Supplement{\_), 2023
H Mays, R Malone, A Nasa, S Salama, M Hennessy, P O'connor, C Kennedy, Including coronary artery calcium scores to guide treatment in a specialist lipid clinic setting, European Journal of Preventive Cardiology, 30, (Supplement{\_), 2023
Cormac Kennedy, Peter Hayes, Sulafa Salama, Martina Hennessy, Federica Fogacci, THE EFFECT OF SEMAGLUTIDE ON BLOOD PRESSURE IN PATIENTS WITHOUT DIABETES: A SYSTEMATIC REVIEW AND META-ANALYSIS, Journal of Hypertension, 41, (Suppl 3), 2023, pe11
R. Malone, P. O'Connor, M. Hennessy, V. Crowley, C. Kennedy, Cardiovascular disease risk modifiers in patients with heterozygous familial hypercholesteremia, Atherosclerosis, 379, 2023, pS119
Kennedy, Cormac, Hayes, Peter, Salama, Sulafa, Hennessy, Martina, Fogacci, Federica, The Effect of Semaglutide on Blood Pressure in Patients without Diabetes: A Systematic Review and Meta-Analysis, Journal of Clinical Medicine, 12, (3), 2023, p772
McErlean S, Mbakaya B, Kennedy C, Familial hypercholesterolaemia., BMJ (Clinical research ed.), 2023
Craig, Hilary C., Alsaeed, Dalal, Norris, Suzanne, Holian, John, Kennedy, Cormac, Feldman, Alix, Le Roux, Carel, Patient perspectives about treatment preferences for obesity with complications, Obesity Science & Practice, 2023
Arrigo Cicero, Giuliano Tocci, Cormac Kennedy, Davide Grassi, Federica Fogacci, CLINICAL EFFICACY AND SAFETY OF TREATMENT WITH BISOPROLOL AND HYDROCHLOROTHIAZIDE: A SYSTEMATIC REVIEW AND META-ANALYSIS, Journal of Hypertension, 41, (Suppl 3), 2023, pe311--e312
C. Kennedy, R. Malone, V. Crowley, M. Barry, M. Hennessy, P. O'Connor, Comparing heterozygous familial hypercholesterolemia phenotype to genotype in an Irish cohort, Atherosclerosis, 379, 2023, pS51
Kennedy, C., Hall, M., O'Connor, P., The patient will see you now: Patient preferences for lipid clinic reviews in a COVID era, Atherosclerosis, 355, 2022, p261
Kennedy, Cormac, Ali, Osama, Farnan, Richard, Stinson, John, Gabr, Ahmed, Hall, Mary, O"Connor, Patricia, Hennessy, Martina, Barry, Michael, Clinical characteristics of two groups commonly referred to an Irish hypertension service"patients with resistant hypertension and young adults with hypertension, Irish Journal of Medical Science (1971 -), 191, (6), 2022, p2549-2557
Emma Prescott, A. Reynolds, Cormac Kennedy, B. Kennedy, S. O'Callagan, U. Geary, Professor Declan Byrne, E. Flynn, Ó. Galvin, H. Kielty, Gerry Hughes, Marie Elizabeth Ward, Ward rounds " A socio-technical system informed analysis of the perceptions of intern and senior house office doctors, Human Factors in Healthcare, 2, 2022, p100027
Offiah, Gregory, O"Connor, Cormac, Kennedy, Cormac, Gallagher, Joe, O"Connor, Patricia, McAdam, Brendan, Ray, Kausik K., Schoonen, Marieke, Maher, Vincent, The DA VINCI study: is Ireland achieving ESC/EAS guideline"directed LDL-C goals?, Irish Journal of Medical Science (1971 -), 2022
Prescott, E., Reynolds, A., Kennedy, C., Kennedy, B., O'Callagan, S., Geary, U., Byrne, D., Flynn, E., Galvin, Ó., Kielty, H., Hughes, G., Ward, M.E., Ward rounds " A socio-technical system informed analysis of the perceptions of intern and senior house office doctors, Human Factors in Healthcare, 2, 2022, p100027
Cormac Kennedy and Osama Ali and Richard Farnan and John Stinson and Ahmed Gabr and Mary Hall and Patricia O'Connor and Martina Hennessy and Michael Barry, Clinical characteristics of two groups commonly referred to an Irish hypertension service"patients with resistant hypertension and young adults with hypertension, Irish Journal of Medical Science (1971 -), 2022
O'Shea M, Kennedy C, Relihan E, Harkin K, Hennessy M, Barry M, Assessment of an Electronic Patient Record System on Discharge Prescribing Errors in a Tertiary University Hospital, 2021
Lincoln, Marc, Gabr, Ahmed, Kennedy, Cormac, Murphy, Catherine, Patterson, Aileen, O"Connor, Enda, Hennessy, Martina, Collaboration, supervision and patient safety in the era of COVID-19: an analysis of medical wards and ICU, Irish Journal of Medical Science (1971 -), 2021
Kennedy C., O'Dea E., Reidy D., Towns J., Pigott M., Kevans D., O'Rourke D., Hennessy M., Challenging times: Delivering gene therapies and an opportunity for shared learning, British Journal of Clinical Pharmacology, 2021
Cormac Kennedy and Amelia Smith and Eoin O'Brien and Jamie Rice and Michael Barry, Prescribers knowledge of drug costs: a contemporary Irish study, Drugs & Therapy Perspectives, 2021
Kennedy C., Ali O., Farnan R., Hall M., Stinson J., O'Connor P., Hennessy M., Barry M., Is it time to reconsider the treatment paradigm for obese patients with hypertension?, Journal of Human Hypertension, 2021
Kennedy, Cormac, Farnan, Richard, Aftal, Zainab, Hall, Mary, Hemyrck, Linda, Stinson, John, O"Connor, Patricia, Hennessy, Martina, Barry, Michael, CLINICAL CHARACTERISTICS OF YOUNG ADULTS WITH HYPERTENSION REFERRED TO A SPECIALIST HYPERTENSION CLINIC, Journal of Hypertension, 39, (Supplement 1), 2021, pe383-e384
Michael Patrick O'Shea and Cormac Kennedy and Eileen Relihan and Kieran Harkin and Martina Hennessy and Michael Barry, Assessment of an electronic patient record system on discharge prescribing errors in a Tertiary University Hospital, BMC Medical Informatics and Decision Making, 21, (1), 2021
Offiah, G, O"Connor, C, Kennedy, C, Gallagher, J, O"Connor, P, McAdam, BF, Ray, KK, Schoonen, M, Maher, V, 14"The DA VINCI study: dyslipidaemia management in Ireland and Europe, BMJ Publishing Group Ltd and British Cardiovascular Society, 2021
Cicero AFG, Kennedy C, Kneževi" T, Bove M, Georges CMG, Šatrauskien" A, Toth PP, Fogacci F., Efficacy and Safety of Armolipid Plus®: An Updated PRISMA Compliant Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials., Nutrients, 13, (2), 2021
Cormac Kennedy, Ahmed Gabr, Joan McCormack, Rónán Collins, Michael Barry & Joe Harbison, The association between increasing oral anticoagulant prescribing and atrial fibrillation related stroke in Ireland , British Journal of Clinical Pharmacology, 2021
Cormac Kennedy and Richard Farnan and John Stinson and Mary Hall and Linda Hemeryck and Patricia O'Connor and Martina Hennessy and Michael Barry, Referrals to, and characteristics of patients attending a specialist hypertension clinic, Journal of Human Hypertension, 2021
Cormac Kennedy and Laura McCullagh and Roisin Adams and Lea Trela-Larsen and Lesley Tilson and Michael Barry, Estimating the Theoretical Cost Implications of Funding New Drugs Considered Not to Be Cost-Effective, Value in Health, 2021
Murray, S., Oderoha, E., O'Shea, M., Chew, B., Kim, S., Geoghegan, L., Kennedy, C., PSY28 The Effect of Medicinal Cannabis on Quality of Life in the Management of NON-Cancer Chronic PAIN: A Systematic Review, Value in Health, 23, 2020, pS747-S748
Kennedy, C., Smith, A., Doran, S., Barry, M., Sacubitril/valsartan (Entresto) utilisation and prescribing patterns in the context of a reimbursement application system, British Journal of Clinical Pharmacology, 2020
Kennedy, C., Ni Choitir, C., Clarke, S., Bennett, K., Barry, M., Direct oral anticoagulants uptake and an oral anticoagulation paradox, British Journal of Clinical Pharmacology, 86, (2), 2020, p392-397
Fogacci F, Rizzo M, Krogager C, Kennedy C, Georges CMG, Kne"evi" T, Liberopoulos E, Vallée A, Pérez-Martínez P, Wenstedt EFE, "atrauskien" A, Vrablík M, Cicero AFG., Safety Evaluation of Alpha-Lipoic Acid Supplementation: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Studies., Antioxidants (Basel, Switzerland), 9, (10), 2020, pdoi.org/10.3390/antiox9101011
Kennedy, C. Brewer, L. Williams, D., Drug interactions, Drug Metabolism Reviews, 48, (7), 2020, p450 - 455
Kennedy, C., Köller, Y., Surkova, E., Effect of Coenzyme Q10 on statin-associated myalgia and adherence to statin therapy: A systematic review and meta-analysis, Atherosclerosis, 299, 2020, p1-8
Smith, A., Doran, S., Daly, M., Kennedy, C., Barry, M., Effect of an Online Reimbursement Application System on Prescribing of Lidocaine 5% Medicated Plaster in the Republic of Ireland, Applied Health Economics and Health Policy, 2020
Kennedy, C., Duggan, E., Bennett, K., Williams, D.J., Rates of reported codeine-related poisonings and codeine prescribing following new national guidance in Ireland, Pharmacoepidemiology and Drug Safety, 28, (1), 2019, p106-111
Kennedy, C., Gullo, G., An elderly patient with a diaphragmatic hernia presenting as decompensated heart failure, Irish Medical Journal, 112, (1), 2019
, Selected Abstracts from Pharmacology 2018, British Journal of Clinical Pharmacology, 85, (7), 2019, p1619-1656
Cormac Kennedy, A review of oral anticoagulant prescribing in the Ireland, British Journal of Clinical Pharmacology, Pharmacology 18, 85, (7), 2019, pp1619-1656
Kennedy, Cormac, OP152 Pharmacoeconomic Assessment And Drug Expenditure Reduction In Ireland, International Journal of Technology Assessment in Health Care, 35, (S1), 2019, p34-34
Cormac Kennedy, Laura McCullagh, Roisin Adams, Lea Trela-Larsen, Lesley Tilson, Michael Barry, Pharmacoeconomic Assessment And Drug Expenditure Reduction In Ireland, 2019, ppdoi.org/10.1017/S0266462319001
Kennedy C, Gullo G., An Elderly Patient with a Diaphragmatic Hernia Presenting as Decompensated Heart Failure, Irish medical journal, 112, (1), 2019, p861
Kennedy, C., Janwar, J., McBride, M., Connolly, E., Tilson, L., Barry, M., PNS164 PHARMACOECONOMIC ASSESSMENT AND DRUG COSTS OF TREATMENTS FOR CANCER AND RARE DISEASES IN IRELAND, Value in Health, 22, 2019, pS788-S789
O"Shea MP, Harkin K, Sulaiman HM, Hennessy M, Barry M, Kennedy C., More Teaching Not More Exams: Interns Views in Improving Prescribing Safety, Irish medical journal, 112, (5), 2019, p943
Kennedy, C., Duggan, E., Bennett, K., Williams, D., Barry, M., Reader response to IMJ article: "codeine usage in ireland " a timely discussion on an imminent epidemic" by E. Mcdonnell, Irish Medical Journal, 112, (4), 2019, p926
Jennifer Mannion, Rebecca Geary, Cormac Kennedy, Katherine O"Reilly, AB149. 57. Proton pump inhibitor prescribing: an audit of a colorectal ward in the Mater Misericordiae University Hospital in 2017, Mesentery and Peritoneum, 2, 2018, pAB149--AB149
Kennedy, Carmel, McDonnell, Tara, Cormac, Kennedy, Bholah, Salmaan, Julius, Valerie, Pazderska, Agnieszka, Louise, Healy Marie, Phelan, Niamh, Knowledge and Attitudes of Trainee Doctors in the Management of DKA and Compliance with current Protocol in a large University Teaching Hospital, 2018
Jennifer Mannion, Rebecca Geary, Cormac Kennedy, Katherine O"Reilly, Proton pump inhibitor prescribing: an audit of a colorectal ward in the Mater Misericordiae University Hospital in 2017, 2, 2018, ppAB149--AB149
Kennedy, Cormac, Ow, Gavin, Bourke, Robert, Fallon, Muireann, Fitzpatrick, Fidelma, Martin, Alan, 078A Study of the Prevalence and Appropriateness of Proton Pump Inhibitor Prescriptions in an Irish Nursing Home Cohort, 46, (Suppl_3), 2017, ppiii13-iii59
Bourke, Robert, Gibbons, Eimear, Murphy, James, Donegan, Ciaran, Williams, David, Kennedy, Cormac, 182An Audit of Appropriate Proton Pump Inhibitor Prescribing in an Older Inpatient Cohort, 46, (Suppl_3), 2017, ppiii13-iii59
Farah, N., Kennedy, C., Turner, C., O'Dwyer, V., Kennelly, M.M., Turner, M.J., Maternal obesity and pre-pregnancy folic acid supplementation, Obesity Facts, 6, (2), 2013, p211-215
Kennedy, C and Robinson, D and Romero-Ortuno, R and O'Shea, D and Kenny, R and Oâ Connell, J, Metabolically healthy obese older adults and functional capacity, European Geriatric Medicine, (4), 2013, pS21
McDonald, C., Pearce, M. S., Newton, J. L., Kerr, S. R. J., Witham, M. D., Price, R. J. G., Struthers, A. D., Donnan, P. T., Ford, I., McMurdo, M. E. T., Romero-Ortuno, R., Finucane, C., O'Connell, M., Kenny, R. A., Kennedy, C., Robinson, D., Romero-Ortuno, R., Savva, G., O'Shea, D., Kenny, R., O'Shea, D., O'Connell, J., Robinson, D. J., O'Donnell, K., Bennett, K., McMahon, G., King-Kallimanis, B. L., Romero-Ortuno, R., O'Shea, D., Kenny, R. A., Peklar, J., Richardson, K., Henman, M. C., Kos, M., Kenny, R. A., Mello, S., O'Connor, K. A., Conroy, S. P., Ewan, V., Sails, A., Walls, A. W. G., Rushton, S., Newton, J. L., Morrison, S., Machniewski, S., Purdy, J., Carlisle, K., Coleman, D., Rea, I. M., O'Donnell, C., Other medical conditions, Age and Ageing, 42, (suppl 3), 2013, piii22-iii24
Cormac Kennedy, Cognitive Outcomes of Metabolically Healthy Obese (MHO) Older Persons, 182, (S6), 2013, pp179-296
Kennedy, C., O'Dwyer, V., O'Kelly, S., Farah, N., Kennelly, M., Turner, M., Thromboprophylaxis for women undergoing caesarean section, Irish Medical Journal, 105, (2), 2012
Kennedy C, Farah N, O'Dwyer V, Hogan J, Kennelly M, Turner MJ., Maternal obesity and inpatient medication usage., Clinical obesity, 1, (4-6), 2011, p147-152
Byrne, C., Kennedy, C., O'Dwyer, V., Farah, N., Kennelly, M., Turner, M.J., What models of maternity care do pregnant women in Ireland want?, Irish Medical Journal, 104, (6), 2011
Chan, F.C., Kennedy, C., Hanson, R.P., O'Sullivan, B., Kelly, J., Bouchier-Hayes, D., Topical diphenylhydantoin sodium can improve healing in a diabetic incisional animal wound model., Journal of wound care, 16, (8), 2007, p359-363
Kennedy, C.A., Chan, F.C., DeVocelle, M., Meaney, C., Bouchier-Hayes, D.J., Kelly, J.G., Synthesis and assessment of a novel peptide conjugate to deliver phenytoin for wound repair, Journal of Drug Delivery Science and Technology, 17, (5), 2007, p309-314
Cormac Kennedy, Claire Meaney, John Kelly, 'Phenytoin Formulations, and Uses Thereof in Wound Healing', World Intellectual Property Organization, WO/2006/013084, 2006, 18 May 2006
Non-Peer-Reviewed Publications
John Kelly, Cormac Kennedy, Clare Meaney, 'Phenytoin formulation and uses thereof in wound healing', WO, 2006, 17 November 2023
Research Expertise
Projects
- Title
- Semaglutide for people with obesity and resistant hypertension trial (SUPPORT): a pilot randomised, double blind, parallel group, integrated, multicentre trial
- Summary
- This study asks the question "does lowering weight using a drug called semaglutide given by injection reduce high blood pressure (BP) in patients with poorly controlled BP and excess body weight (obesity)". This is important because although we know high BP can lead to serious health problems such as a heart failure, we have not considered BP treatment from the viewpoint of weight reduction with a drug before. The risk of heart disease from high BP is reduced by medicines, but they don't work for everyone and multiple drugs may be needed. This is called resistant hypertension and it is associated with excess weight. By reducing weight we expect a lower BP. This should mean the risk of an unhealthy heart is also lower. To test this idea, suitable people with high BP and weight are invited into the study. If they agree, their weight, height and BP are measured and volunteers are trained to inject the study medicine themselves. To test the medicine, every second person involved will get the active medicine, while the others will continue with their current treatment plan. The medicine is considered safe and may help the person lose weight. Advice about a healthy lifestyle is provided. At the beginning and end of the study, blood tests are taken, BP and weight are measured and participants are asked to answer questionnaires. Weight and BP will be measured every 12 weeks thereafter for 36 weeks. First, a small study will inform how a larger study can be best planned and delivered as part of routine hospital or GP care. We expect the larger study to bring about an important breakthrough in how patients with obesity and hypertension are treated. Ultimately, this will help us to understand whether weight lowering medicines can be used to improve difficult to control blood pressure, health and well-being.
- Funding Agency
- Health Research Board
- Date From
- October 2023