Professor Daniel Bradley
Professor, Genetics
Biography
Dan Bradley was brought up on a Northern Irish farm and after a degree in Genetics from Cambridge University and PhD in medical genetics from Trinity College Dublin he started to work on the genetics of each species present on that farm, including Irish humans, and has done for over 30 years. With his colleagues he has combined analysis of ancient and modern cattle to inform on the origins of these and other domesticates and pioneered the molecular genetic analysis of Irish populations. He holds a Personal Chair in Population Genetics in Trinity and was awarded the 2020 Royal Irish Academy Gold Medal in the Life Sciences
Publications and Further Research Outputs
Peer-Reviewed Publications
Ring, S.C. and Purfield, D.C. and Good, M. and Breslin, P. and Ryan, E. and Blom, A. and Evans, R.D. and Doherty, M.L. and Bradley, D.G. and Berry, D.P., Variance components for bovine tuberculosis infection and multi-breed genome-wide association analysis using imputed whole genome sequence data, PLoS ONE, 14, (2), 2019
Verdugo, M.P. and Mullin, V.E. and Scheu, A. and Mattiangeli, V. and Daly, K.G. and Maisano Delser, P. and Hare, A.J. and Burger, J. and Collins, M.J. and Kehati, R. and Hesse, P. and Fulton, D. and Sauer, E.W. and Mohaseb, F.A. and Davoudi, H. and Khazaeli, R. and Lhuillier, J. and Rapin, C. and Ebrahimi, S. and Khasanov, M. and Vahidi, S.M.F. and MacHugh, D.E. and ErtuÄ rul, O. and Koukouli-Chrysanthaki, C. and Sampson, A. and Kazantzis, G. and Kontopoulos, I. and Bulatovic, J. and StojanoviÄ , I. and Mikdad, A. and Benecke, N. and LinstÀdter, J. and Sablin, M. and Bendrey, R. and Gourichon, L. and Arbuckle, B.S. and Mashkour, M. and Orton, D. and Horwitz, L.K. and Teasdale, M.D. and Bradley, D.G., Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent, Science (New York, N.Y.), 365, (6449), 2019, p173-176
Frantz, L.A.F. and Haile, J. and Lin, A.T. and Scheu, A. and Geörg, C. and Benecke, N. and Alexander, M. and Linderholm, A. and Mullin, V.E. and Daly, K.G. and Battista, V.M. and Price, M. and Gron, K.J. and Alexandri, P. and Arbogast, R.-M. and Arbuckle, B. and BÇ lÇ Å escu, A. and Barnett, R. and Bartosiewicz, L. and Baryshnikov, G. and Bonsall, C. and BoriÄ , D. and BoroneanÅ£, A. and BulatoviÄ , J. and à akirlar, C. and Carretero, J.-M. and Chapman, J. and Church, M. and Crooijmans, R. and De Cupere, B. and Detry, C. and Dimitrijevic, V. and DumitraÅ cu, V. and Du Plessis, L. and Edwards, C.J. and Erek, C.M. and Erim-Ã-zdoǧan, A. and Ervynck, A. and Fulgione, D. and Gligor, M. and Götherström, A. and Gourichon, L. and Groenen, M.A.M. and Helmer, D. and Hongo, H. and Horwitz, L.K. and Irving-Pease, E.K. and Lebrasseur, O. and Lesur, J. and Malone, C. and Manaseryan, N. and Marciniak, A. and Martlew, H. and Mashkour, M. and Matthews, R. and Matuzeviciute, G.M. and Maziar, S. and Meijaard, E. and McGovern, T. and Megens, H.-J. and Miller, R. and Mohaseb, A.F. and Orschiedt, J. and Orton, D. and Papathanasiou, A. and Pearson, M.P. and Pinhasi, R. and RadmanoviÄ , D. and Ricaut, F.-X. and Richards, M. and Sabin, R. and Sarti, L. and Schier, W. and Sheikhi, S. and Stephan, E. and Stewart, J.R. and Stoddart, S. and Tagliacozzo, A. and TasiÄ , N. and Trantalidou, K. and Tresset, A. and Valdiosera, C. and Van Den Hurk, Y. and Van Poucke, S. and Vigne, J.-D. and Yanevich, A. and Zeeb-Lanz, A. and Triantafyllidis, A. and Gilbert, M.T.P. and Schibler, J. and Rowley-Conwy, P. and Zeder, M. and Peters, J. and Cucchi, T. and Bradley, D.G. and Dobney, K. and Burger, J. and Evin, A. and Girdland-Flink, L. and Larson, G., Ancient pigs reveal a near-complete genomic turnover following their introduction to Europe, Proceedings of the National Academy of Sciences of the United States of America, 116, (35), 2019, p17231-17238
Daly, K.G. and Delser, P.M. and Mullin, V.E. and Scheu, A. and Mattiangeli, V. and Teasdale, M.D. and Hare, A.J. and Burger, J. and Verdugo, M.P. and Collins, M.J. and Kehati, R. and Erek, C.M. and Bar-Oz, G. and Pompanon, F. and Cumer, T. and à akırlar, C. and Mohaseb, A.F. and Decruyenaere, D. and Davoudi, H. and à evik, Ã-. and Rollefson, G. and Vigne, J.-D. and Khazaeli, R. and Fathi, H. and Doost, S.B. and Sorkhani, R.R. and Vahdati, A.A. and Sauer, E.W. and Kharanaghi, H.A. and Maziar, S. and Gasparian, B. and Pinhasi, R. and Martin, L. and Orton, D. and Arbuckle, B.S. and Benecke, N. and Manica, A. and Horwitz, L.K. and Mashkour, M. and Bradley, D.G., Ancient goat genomes reveal mosaic domestication in the Fertile Crescent, Science, 361, (6397), 2018, p85-88
Cahill, J.A. and Heintzman, P.D. and Harris, K. and Teasdale, M.D. and Kapp, J. and Soares, A.E.R. and Stirling, I. and Bradley, D. and Edwards, C.J. and Graim, K. and Kisleika, A.A. and Malev, A.V. and Monaghan, N. and Green, R.E. and Shapiro, B., Genomic Evidence of Widespread Admixture from Polar Bears into Brown Bears during the Last Ice Age, Molecular biology and evolution, 35, (5), 2018, p1120-1129
Chen, N. and Cai, Y. and Chen, Q. and Li, R. and Wang, K. and Huang, Y. and Hu, S. and Huang, S. and Zhang, H. and Zheng, Z. and Song, W. and Ma, Z. and Ma, Y. and Dang, R. and Zhang, Z. and Xu, L. and Jia, Y. and Liu, S. and Yue, X. and Deng, W. and Zhang, X. and Sun, Z. and Lan, X. and Han, J. and Chen, H. and Bradley, D.G. and Jiang, Y. and Lei, C., Whole-genome resequencing reveals world-wide ancestry and adaptive introgression events of domesticated cattle in East Asia, Nature Communications, 9, (1), 2018
Byrne RP, Martiniano R, Cassidy LM, Carrigan M, Hellenthal G, Hardiman O, Bradley DG, McLaughlin RL, Insular Celtic population structure and genomic footprints of migration, PLOS Genetics, 14, 2018, pe1007152
Maixner, F. and Turaev, D. and Cazenave-Gassiot, A. and Janko, M. and Krause-Kyora, B. and Hoopmann, M.R. and Kusebauch, U. and Sartain, M. and Guerriero, G. and O'Sullivan, N. and Teasdale, M. and Cipollini, G. and Paladin, A. and Mattiangeli, V. and Samadelli, M. and Tecchiati, U. and Putzer, A. and Palazoglu, M. and Meissen, J. and Lösch, S. and Rausch, P. and Baines, J.F. and Kim, B.J. and An, H.-J. and Gostner, P. and Egarter-Vigl, E. and Malfertheiner, P. and Keller, A. and Stark, R.W. and Wenk, M. and Bishop, D. and Bradley, D.G. and Fiehn, O. and Engstrand, L. and Moritz, R.L. and Doble, P. and Franke, A. and Nebel, A. and Oeggl, K. and Rattei, T. and Grimm, R. and Zink, A., The Iceman's Last Meal Consisted of Fat, Wild Meat, and Cereals, Current Biology, 2018, p2348-2355
Stella, A. and Nicolazzi, E.L. and Van Tassell, C.P. and Rothschild, M.F. and Colli, L. and Rosen, B.D. and Sonstegard, T.S. and Crepaldi, P. and Tosser-Klopp, G. and Joost, S. and Amills, M. and Ajmone-Marsan, P. and Bertolini, F. and Boettcher, P. and Boyle Onzima, R. and Bradley, D. and Buja, D. and Cano Pereira, M.E. and Carta, A. and Catillo, G. and Crisà , A. and Del Corvo, M. and Daly, K. and Droegemueller, C. and Duruz, S. and Elbeltagi, A. and Esmailizadeh, A. and Faco, O. and Figueiredo Cardoso, T. and Flury, C. and Garcia, J.F. and Guldbrandtsen, B. and Haile, A. and Hallsteinn Hallsson, J. and Heaton, M. and Hunnicke Nielsen, V. and Huson, H. and Kijas, J. and Lenstra, J.A. and Marras, G. and Milanesi, M. and Minhui, C. and Moaeen-Ud-Din, M. and Morry O'Donnell, R. and Moses Danlami, O. and Mwacharo, J. and PalhiÚre, I. and Pilla, F. and Poli, M. and Reecy, J. and Rischkowsky, B.A. and Rochat, E. and Rupp, R. and Sayre, B. and Servin, B. and Silva, K. and Spangler, G. and Steri, R. and Talenti, A. and Tortereau, F. and Vajana, E. and Zhang, W., AdaptMap: Exploring goat diversity and adaptation, Genetics Selection Evolution, 50, (1), 2018
Schroeder, H. and Sikora, M. and Gopalakrishnan, S. and Cassidy, L.M. and Delser, P.M. and Velasco, M.S. and Schraiber, J.G. and Rasmussen, S. and Homburger, J.R. and à vila-Arcos, M.C. and Allentoft, M.E. and VÃctor Moreno-Mayar, J. and Renaud, G. and Gómez-Carballa, A. and Laffoon, J.E. and Hopkins, R.J.A. and Higham, T.F.G. and Carr, R.S. and Schaffer, W.C. and Day, J.S. and Hoogland, M. and Salas, A. and Bustamante, C.D. and Nielsen, R. and Bradley, D.G. and Hofman, C.L. and Willerslev, E., Origins and genetic legacies of the Caribbean Taino, Proceedings of the National Academy of Sciences of the United States of America, 115, (10), 2018, p2341-2346
CookeN., Bradley D.G., Nakagome S., A simulation study on the origin of natural selection in an admixed population, Irish Society of Human Genetics 2018, Dublin, Ireland, September 21st, 2018
Lara M. Cassidy, Matthew D. Teasdale, Sean Carolan, Ruth Enright, Raymond Werner, Daniel G. Bradley, Emma K. Finlay, Valeria Mattiangeli, Capturing goats: Documenting two hundred years of mitochondrial DNA diversity among goat populations from Britain and Ireland, Biology Letters, Volume 13, (Issue 3), 2017
Martiniano R, Cassidy LM, Ó'Maoldúin R, McLaughlin R, Silva NM, Manco L, Fidalgo D, Pereira T, Coelho MJ, Serra M, Burger J, Parreira R, Moran E, Valera AC, Porfirio E, Boaventura R, Silva AM, Bradley DG., The population genomics of archaeological transition in west Iberia: Investigation of ancient substructure using imputation and haplotype-based methods, PLoS Genetics, 13, 2017, pe1006852
Siska, V. and Jones, E.R. and Jeon, S. and Bhak, Y. and Kim, H.-M. and Cho, Y.S. and Kim, H. and Lee, K. and Veselovskaya, E. and Balueva, T. and Gallego-Llorente, M. and Hofreiter, M. and Bradley, D.G. and Eriksson, A. and Pinhasi, R. and Bhak, J. and Manica, A., Genome-wide data from two early Neolithic East Asian individuals dating to 7700 years ago, Science Advances, 3, (2), 2017, pe1601877. -
Jones, E.R. and Zarina, G. and Moiseyev, V. and Lightfoot, E. and Nigst, P.R. and Manica, A. and Pinhasi, R. and Bradley, D.G., The Neolithic Transition in the Baltic Was Not Driven by Admixture with Early European Farmers, Current Biology, 27, (4), 2017, p576-582
Hollund H.I, Teasdale M.D, Mattiangeli V, Sverrisdóttir O.O, Bradley D.G, O'Connor T, Pick the Right Pocket. Sub-sampling of Bone Sections to Investigate Diagenesis and DNA Preservation, International Journal of Osteoachaeology, 27, (3), 2017, p365-374
Teasdale, M.D. and Fiddyment, S. and VnouÄ ek, J. and Mattiangeli, V. and Speller, C. and Binois, A. and Carver, M. and Dand, C. and Newfield, T.P. and Webb, C.C. and Bradley, D.G. and Collins, M.J., The york gospels: A 1000-year biological palimpsest, Royal Society Open Science, 4, (10), 2017
McLaughlin RL, Schijven D, van Rheenen W, van Eijk KR, O'Brien M, Kahn RS, Ophoff RA, Goris A, Bradley DG, Al-Chalabi A, van den Berg LH, Luykx JJ, Hardiman O, Veldink JH, Project MinE GWAS Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Genetic correlation between amyotrophic lateral sclerosis and schizophrenia., Nature Communications, 2017, p14774
Llorente, M.G. and Jones, E.R. and Eriksson, A. and Siska, V. and Arthur, K.W. and Arthur, J.W. and Curtis, M.C. and Stock, J.T. and Coltorti, M. and Pieruccini, P. and Stretton, S. and Brock, F. and Higham, T. and Park, Y. and Hofreiter, M. and Bradley, D.G. and Bhak, J. and Pinhasi, R. and Manica, A., Erratum: Ancient Ethiopian genome reveals extensive Eurasian admixture in Eastern Africa (Science (2016) 351:6275)), Science, 351, (6275), 2016
Richardson I.W, Berry D.P, Wiencko H.L, Higgins I.M, More S.J, McClure J, Lynn D.J, Bradley D.G, A genome-wide association study for genetic susceptibility to Mycobacterium bovis infection in dairy cattle identifies a susceptibility QTL on chromosome 23, Genetics Selection Evolution, 48, (1), 2016, p19-
Cassidy L.M, Martiniano R, Murphy E.M, Teasdale M.D, Mallory J, Hartwell B, Bradley D.G, Neolithic and Bronze Age migration to Ireland and establishment of the insular atlantic genome, Proceedings of the National Academy of Sciences of the United States of America, 113, (2), 2016, p368 - 373
O'Sullivan N.J, Teasdale M.D, Mattiangeli V, Maixner F, Pinhasi R, Bradley D.G, Zink A, A whole mitochondria analysis of the Tyrolean Iceman's leather provides insights into the animal sources of Copper Age clothing, Scientific Reports, 6, 2016, p31279 -
Iyer P.M, Fagan A.J, Meaney J.F, Colgan N.C, Meredith S.D, Driscoll D.O, Curran K.M, Bradley D, Redmond J, Horizontal nystagmus and multiple sclerosis using 3-Tesla magnetic resonance imaging, Irish Journal of Medical Science, 185, (4), 2016, p881-886
Frantz L.A, Mullin V.E, Pionnier-Capitan M, Lebrasseur O, Ollivier M, Perri A, Linderholm A, Mattiangeli V, Teasdale M.D, Dimopoulos E.A, Tresset A, Duffraisse M, McCormick F, Bartosiewicz L, Gál E, Nyerges à A, Sablin M.V, Bréhard S, Mashkour M, BÄ lÄ Å escu A, Gillet B, Hughes S, Chassaing O, Hitte C, Vigne J.-D, Dobney K, HÀnni C, Bradley D.G, Larson G, Genomic and archaeological evidence suggest a dual origin of domestic dogs, Science (New York, N.Y.), 352, (6290), 2016, p1228 - 1231
Broushaki F, Thomas M.G, Link I, López S, Van Dorp L, Kirsanow K, Hofmanová Z, Diekmann Y, Cassidy L.M, DÃez-Del-Molino D, Kousathanas A, Sell C, Robson H.K, Martiniano R, Blöcher J, Scheu A, Kreutzer S, Bollongino R, Bobo D, Davoudi H, Munoz O, Currat M, Abdi K, Biglari F, Craig O.E, Bradley D.G, Shennan S, Veeramah K.R, Mashkour M, Wegmann D, Hellentha G, Burger J, Early Neolithic genomes from the eastern Fertile Crescent, Science, 353, (6298), 2016, p499 - 503
Gamba, C. and HanghÞj, K. and Gaunitz, C. and Alfarhan, A.H. and Alquraishi, S.A. and Al-Rasheid, K.A.S. and Bradley, D.G. and Orlando, L., Comparing the performance of three ancient DNA extraction methods for high-throughput sequencing, Molecular Ecology Resources, 16, (2), 2016, p459-469
Hofmanová Z, Kreutzer S, Hellenthal G, Sell C, Diekmann Y, DÃez-Del-Molino D, Van Dorp L, López S, Kousathanas A, Link V, Kirsanow K, Cassidy L.M, Martiniano R, Strobel M, Scheu A, Kotsakis K, Halstead P, Triantaphyllou S, Kyparissi-Apostolika N, Urem-Kotsou D, Ziota C, Adaktylou F, Gopalan S, Bobo D.M, Winkelbach L, Blöcher J, UnterlÀnder M, Leuenberger C, à ilingiroǧlu C, Horejs B, Gerritsen F, Shennan S.J, Bradley D.G, Currat M, Veeramah K.R, Wegmann D, Thomas M.G, Papageorgopoulou C, Burger J, Early farmers from across Europe directly descended from Neolithic Aegeans, Proceedings of the National Academy of Sciences of the United States of America, 113, (25), 2016, p6886 - 6891
Martiniano R, Caffell A, Holst M, Hunter-Mann K, Montgomery J, MÃ"ldner G, McLaughlin R.L, Teasdale M.D, Van Rheenen W, Veldink J.H, Van Den Berg L.H, Hardiman O, Carroll M, Roskams S, Oxley J, Morgan C, Thomas M.G, Barnes I, McDonnell C, Collins M.J, Bradley D.G, Genomic signals of migration and continuity in Britain before the Anglo-Saxons, Nature Communications, 7, 2016, 10326-
Jones ER, Gonzalez-Fortes G, Connell S, Siska V, Eriksson A, Martiniano R, McLaughlin RL, Gallego Llorente M, Cassidy LM, Gamba C, Meshveliani T, Bar-Yosef O, Müller W, Belfer-Cohen A, Matskevich Z, Jakeli N, Higham TF, Currat M, Lordkipanidze D, Hofreiter M, Manica A, Pinhasi R, Bradley DG, Upper Palaeolithic genomes reveal deep roots of modern Eurasians., Nature communications, 6, 2015, p8912
Russell Lewis McLaughlin, Kevin P Kenna, Alice Vajda, Peter Bede, Marwa Elamin, Simon Cronin, Colette G Donaghy, Daniel G Bradley, Orla Hardiman, A second-generation Irish genome-wide association study for amyotrophic lateral sclerosis, Neurobiology of Aging , 36, (2), 2015, p1221.e7-1221.e13
Teasdale, M.D. van Doorn, N.L. Fiddyment, S. Webb, C.C. O-Connor, T. Hofreiter, M. Collins, M.J. Bradley, D.G., Paging through history: Parchment as a reservoir of ancient DNA for next generation sequencing, Philosophical Transactions B, 370, (1660), 2015, p1-7
Gargani, M. Pariset, L. Lenstra, J.A. De Minicis, E. Moazami-Goudarzi, K. Laloë, D. Williams, J.L. Wiener, P. Bradley, D.G. Erhardt, G. Harlizius, B. Medugorac, I. Looft, M.C. Kalm, E. Cañón, J. Dunner, S. Rodellar, C. Martín-Burriel, I. Sanchez, A. Martínez, A.M. Ginja, C. Ajmone-Marsan, P. Pilla, F. Bruzzone, A. Marletta, D. Holm, L.E. Dolf, G. Valentini, A., Microsatellite genotyping of medieval cattle from central Italy suggests an old origin of Chianina and Romagnola cattle, Frontiers of Genetics, 5, (FEB), 2015, p68-
Bede P, Elamin M, Byrne S, McLaughlin RL, Kenna K, Vajda A, Fagan A, Bradley DG, Hardiman O., Patterns of cerebral and cerebellar white matter degeneration in ALS., J Neurol Neurosurg Psychiatry, 86, (4), 2015, p468-470
McLaughlin RL, Kenna KP, Vajda A, Bede P, Elamin M, Cronin S, Donaghy CG, Bradley DG, Hardiman O, Second-generation Irish genome-wide association study for amyotrophic lateral sclerosis., Neurobiology of aging, 36, (2), 2015, p1221.e7-13
Aloraifi F, McDevitt T, Martiniano R, McGreevy J, McLaughlin R, Egan CM, Cody N, Meany M, Kenny E, Green AJ, Bradley DG, Geraghty JG, Bracken AP., Detection of novel germline mutations for breast cancer in non-BRCA1/2 families., FEBS J., 282, (17), 2015, p3424 - 3437
Purfield D.C, Bradley D.G, Evans R.D, Kearney F.J, Berry D.P, Genome-wide association study for calving performance using high-density genotypes in dairy and beef cattle, Genetics Selection Evolution, 47, (1), 2015
Kassahun Y, Mattiangeli V, Ameni G, Hailu E, Aseffa A, Young D.B, Hewinson R.G, Vordermeier H.M, Bradley D.G, Admixture mapping of tuberculosis and pigmentation-related traits in an African-European hybrid cattle population, Frontiers in Genetics, 6, (JUN), 2015
McLaughlin RL, Kenna KP, Vajda A, Heverin M, Byrne S, Donaghy CG, Cronin S, Bradley DG, Hardiman O, Homozygosity mapping in an Irish ALS case-control cohort describes local demographic phenomena and points towards potential recessive risk loci., Genomics, 105, (4), 2015, p237-41
McLaughlin RL, Kenna KP, Vajda A, Heverin M, Byrne S, Donaghy CG, Cronin S, Bradley DG, Hardiman O., Homozygosity mapping in an Irish ALS case-control cohort describes local demographic phenomena and points towards potential recessive risk loci, Genomics , 105, (4), 2015, p237-241
Vegh, P. Magee, D.A. Nalpas, N.C. Bryan, K. McCabe, M.S. Browne, J.A. Conlon, K.M. Gordon, S.V. Bradley, D.G. Machugh, D.E. Lynn, D.J., MicroRNA profiling of the bovine alveolar macrophage response to Mycobacterium bovis infection suggests pathogen survival is enhanced by microRNA regulation of endocytosis and lysosome trafficking, Tuberculosis, 95, (1), 2015, p60 - 67
Fiddyment S, Holsinger B, Ruzzier C, Devine A, Binois A, Albarella U, Fischer R, Nichols E, Curtis A, Cheese E, Teasdale M.D, Checkley-Scott C, Milner S.J, Rudy K.M, Johnson E.J, Vnoucek J, Garrison M, McGrory S, Bradley D.G, Collins M.J, Animal origin of 13th-century uterine vellum revealed using noninvasive peptide fingerprinting, Proceedings of the National Academy of Sciences of the United States of America, 112, (49), 2015, p15066 - 15071
Sanderson, N.D. Norman, P.J. Guethlein, L.A. Ellis, S.A. Williams, C. Breen, M. Park, S.D.E. Magee, D.A. Babrzadeh, F. Warry, A. Watson, M. Bradley, D.G. MacHugh, D.E. Parham, P. Hammond, J.A., Definition of the cattle killer cell Ig-like receptor gene family: Comparison with aurochs and human counterparts, Journal of Immunology, 193, (12), 2014, p6016 - 6030
Fahey C, Byrne S, McLaughlin R, Kenna K, Shatunov A, Donohoe G, Gill M, Al-Chalabi A, Bradley DG, Hardiman O, Corvin AP, Morris DW, Analysis of the hexanucleotide repeat expansion and founder haplotype at C9ORF72 in an Irish psychosis case-control sample., Neurobiology of aging, 35, (6), 2014, p1510.e1-1510.e5
Authors of Document Lenstra, J.A., Ajmone-Marsan, P., Beja-Pereira, A., (...), Negrini, R., Radoslavov, G.A. , Meta-Analysis of mitochondrial DNA reveals several population bottlenecks during worldwide migrations of cattle , Diversity, 6, (1), 2014, p178-187
McLaughlin RL, Kenna KP, Vajda A, Byrne S, Bradley DG, Hardiman O, UBQLN2 mutations are not a frequent cause of amyotrophic lateral sclerosis in Ireland., Neurobiology of aging, 35, (1), 2014, p267.e9-11
Utsunomiya, YT, Bomba, L, Lucente, G, Colli, L, Negrini, R, Lenstra, JA, Erhardt, G, Garcia, JF, Ajmone-Marsan, P, European Cattle Genetic Diversity, Revisiting AFLP fingerprinting for an unbiased assessment of genetic structure and differentiation of taurine and zebu cattle, BMC GENETICS, 15, 2014, p47-
Purfield, DC, Bradley, DG, Kearney, JF, Berry, DP, Genome-wide association study for calving traits in Holstein-Friesian dairy cattle, ANIMAL, 8, (2), 2014, p224-235
Gerbault, P, Allaby, RG, Boivin, N, Rudzinski, A, Grimaldi, IM, Pires, JC, Vigueira, CC, Dobney, K, Gremillion, KJ, Barton, L, Arroyo-Kalin, M, Purugganan, MD, de Casas, RR, Bollongino, R, Burger, J, Fuller, DQ, Bradley, DG, Balding, DJ, Richerson, PJ, Gilbert, MTP, Larson, G, Thomas, MG, Storytelling and story testing in domestication, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111, (17), 2014, p6159-6164
Larson, G., Bradley, D.G., How Much Is That in Dog Years? The Advent of Canine Population Genomics, PLoS Genetics, 10, (1), 2014, pe1004093-
P. Bede, M. Elamin, S. Byrne, R.L. McLaughlin, K.Kenna, A. Vajda, A.J. Fagan, D.G. Bradley, Patterns of cerebral and cerebellar white matter degeneration in ALS, Journal of neurology, neurosurgery, and psychiatry, 2014
Richardson, I.W. Bradley, D.G. Higgins, I.M. More, S.J. Mcclure, J. Berry, D.P., Variance components for susceptibility to Mycobacterium bovis infection in dairy and beef cattle, Genetics Selection Evolution, 46, 2014, p77 -
Martiniano, R. Coelho, C. Ferreira, M.T. Neves, M.J. Pinhasi, R. Bradley, D.G., Genetic evidence of African slavery at the beginning of the Trans-Atlantic slave trade, Scientific Reports, 4, 2014, p5994-
Connell, S, Meade, KG, Allan, B, Lloyd, AT, Downing, T, O'Farrelly, C, Bradley, DG, Genome-Wide Association Analysis of Avian Resistance to Campylobacter jejuni Colonization Identifies Risk Locus Spanning the CDH13 Gene, G3-GENES GENOMES GENETICS, 3, (5), 2013, p881-890
Meredith, B.K. Berry, D.P. Kearney, F. Finlay, E.K. Fahey, A.G. Bradley, D.G. Lynn, D.J., A genome-wide association study for somatic cell score using the Illumina high-density bovine beadchip identifies several novel QTL potentially related to mastitis susceptibility, Frontiers in Genetics, 4, (NOV), 2013, p229-
Vegh, P, Foroushani, ABK, Magee, DA, McCabe, MS, Browne, JA, Nalpas, NC, Conlon, KM, Gordon, SV, Bradley, DG, MacHugh, DE, Lynn, DJ, Profiling microRNA expression in bovine alveolar macrophages using RNA-seq, VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 155, (4), 2013, p238-244
Bede, P, Elamin, M, Byrne, S, McLaughlin, RL, Kenna, K, Vajda, A, Pender, N, Bradley, DG, Hardiman, O, Basal ganglia involvement in amyotrophic lateral sclerosis, NEUROLOGY, 81, (24), 2013, p2107-2115
Kenna, K.P., Mclaughlin, R.L., Hardiman, O., Bradley, D.G., Using Reference Databases of Genetic Variation to Evaluate the Potential Pathogenicity of Candidate Disease Variants, Human Mutation, 34, (6), 2013, p836-841
Kenna, KP, McLaughlin, RL, Hardiman, O, Bradley, DG, Using Reference Databases of Genetic Variation to Evaluate the Potential Pathogenicity of Candidate Disease Variants, HUMAN MUTATION, 34, (6), 2013, p836-841
Zhang, HC, Paijmans, JLA, Chang, FQ, Wu, XH, Chen, GJ, Lei, CZ, Yang, XJ, Wei, ZY, Bradley, DG, Orlando, L, O'Connor, T, Hofreiter, M, Morphological and genetic evidence for early Holocene cattle management in northeastern China, NATURE COMMUNICATIONS, 4, 2013
Finlay EK, Berry DP, Wickham B, Gormley EP, Bradley DG, A Genome Wide Association Scan of Bovine Tuberculosis Susceptibility in Holstein-Friesian Dairy Cattle, PLoS ONE, 7 , (2, e30545), 2012
Bower, M.A., McGivney, B.A., Campana, M.G., Gu, J., Andersson, L.S., Barrett, E., Davis, C.R., (...), Hill, E.W.., The genetic origin and history of speed in the Thoroughbred racehorse, Nature Communications , 3, 2012, part. no. 643
Edwards, C.J., Soulsbury, C.D., Statham, M.J., Ho, S.Y.W., Wall, D., Dolf, G., Iossa, G., (...), Bradley, D.G., Temporal genetic variation of the red fox, Vulpes vulpes, across western Europe and the British Isles, Quaternary Science Reviews, 57, (4), 2012, 95-104
Carden, R.F., McDevitt, A.D., Zachos, F.E., Woodman, P.C., O'Toole, P., Rose, H., Monaghan, N.T., (...), Edwards, C.J., Phylogeographic, ancient DNA, fossil and morphometric analyses reveal ancient and modern introductions of a large mammal: The complex case of red deer (Cervus elaphus) in Ireland, Quaternary Science Reviews, 42, 2012, p74-84
Busby, G.B.J., Brisighelli, F., Sánchez-Diz, P., Ramos-Luis, E., Martinez-Cadenas, C., Thomas, M.G., Bradley, D.G., (...), Capelli, C., The peopling of Europe and the cautionary tale of Y chromosome lineage R-M269, Proceedings of the Royal Society B: Biological Sciences, 279, (1730), 2012, p884-892
Meredith, B.K., Kearney, F.J., Finlay, E.K., Bradley, D.G., Fahey, A.G., Berry, D.P., Lynn, D.J., Genome-wide associations for milk production and somatic cell score in Holstein-Friesian cattle in Ireland, BMC Genetics, 13, 2012, part. no. 21
Purfield, D.C., Berry, D.P., McParland, S., Bradley, D.G., Runs of homozygosity and population history in cattle, BMC Genetics, 13, 2012, part. no. 70
Byrne S, Elamin M, Bede P, Shatunov A, Walsh C, Corr B, Heverin M, Jordan N, Kenna K, Lynch C, McLaughlin RL, Iyer PM, O'Brien C, Phukan J, Wynne B, Bokde AL, Bradley DG, Pender N, Al-Chalabi A, Hardiman O, Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study., Lancet neurology, 11, (3), 2012, p232-40
Connell S, Meade KG, Allan B, Lloyd AT, Kenny E, Cormican P, Morris DW, Bradley DG, O'Farrelly C, Avian resistance to Campylobacter jejuni colonization is associated with an intestinal immunogene expression signature identified by mRNA sequencing., PloS one, 7, (8), 2012, pe40409
le Roex, N., Noyes, H., Brass, A., Bradley, D.G., Kemp, S.J., Kay, S., van Helden, P.D., Hoal, E.G., Novel SNP Discovery in African Buffalo, Syncerus caffer, Using High-Throughput Sequencing, PLoS ONE, 7, (11), 2012, part. no. e48792
O'Meara, D.B., Edwards, C.J., Sleeman, D.P., Cross, T.F., Statham, M.J., McDowell, J.R., Dillane, E., (...), Carlsson, J.., Genetic structure of Eurasian badgers Meles meles (Carnivora: Mustelidae) and the colonization history of Ireland, Biological Journal of the Linnean Society, 106, (4), 2012, p893-909
Ceiridwen J. Edwards, Catarina Ginja, Juha Kantanen, Lucía Pérez-Pardal, Anne Tresset, Frauke Stock, European Cattle Genetic Diversity Consortium Luis T. Gama, M. Cecilia T. Penedo, Daniel G. Bradley,Johannes A. Lenstra, Isaäc J. Nijman, Dual Origins of Dairy Cattle Farming - Evidence from a Comprehensive Survey of European Y-Chromosomal Variation, PLoS ONE, 6, (1, e15922), 2011
Noyes H, Brass A, Obara I, Anderson S, Archibald AL, Bradley DG, Fisher P, Freeman A, Gibson J, Gicheru M, Hall L, Hanotte O, Hulme H, McKeever D, Murray C, Oh SJ, Tate C, Smith K, Tapio M, Wambugu J, Williams DJ, Agaba M, Kemp SJ, Genetic and expression analysis of cattle identifies candidate genes in pathways responding to Trypanosoma congolense infection., Proceedings of the National Academy of Sciences of the United States of America, 108, (22), 2011, p9304-9
Ceiridwen J. Edwards, Marc A. Suchard, Philippe Lemey, John J. Welch, Ian Barnes, Tara L. Fulton, Ross Barnett, Tamsin C. O'Connell, Peter Coxon, Nigel Monaghan, Cristina E. Valdiosera, Eline D. Lorenzen, Eske Willerslev, Gennady F. Baryshnikov, Andrew Rambaut, Mark G. Thomas, Daniel G. Bradley and Beth Shapiro, Ancient Hybridization and an Irish Origin for the Modern Polar Bear Matriline, Current Biology, 21, (15), 2011, p1251 - 1258
Downing, T., O'Farrelly, C., Bhuiyan, A.K., Silva, P., Naqvi, A.N., Sanfo, R., Sow, R.-S., (...), Bradley, D.G.., Variation in chicken populations may affect the enzymatic activity of lysozyme, Animal Genetics, 41, (2), 2010, p213-217
Chen, S., Lin, B.-Z., Baig, M., Mitra, B., Lopes, R.J., Santos, A.M., Magee, D.A., (...), Beja-Pereira, A., Zebu cattle are an exclusive legacy of the South Asia neolithic, Molecular Biology and Evolution, 27, (1), 2010, p1-6
Russell Lewis McLaughlin, Julie Phukan, William McCormack, David S. Lynch, Matthew Greenway, Simon Cronin, Jean Saunders, Agnieska Slowik, Barbara Tomik, Peter M. Andersen, Daniel G. Bradley, Phil Jakeman, Orla Hardiman, Angiogenin Levels and ANG Genotypes: Dysregulation in Amyotrophic Lateral Sclerosis, PloS ONE, 5, (11), 2010, pe15402
Magee, D.A., Berkowicz, E.W., Sikora, K.M., Sweeney, T., Kenny, D.A., Kelly, A.K., Evans, R.D., (...), MacHugh, D.E., High concordance of bovine single nucleotide polymorphism genotypes generated using two independent genotyping strategies, Animal Biotechnology , 21, (4), 2010, 257-262
Tong P, Prendergast JG, Lohan AJ, Farrington SM, Cronin S, Friel N, Bradley DG, Hardiman O, Evans A, Wilson JF, Loftus B, Sequencing and analysis of an Irish human genome., Genome Biology, 11, (9), 2010, pR91
Edwards, C.J., Magee, D.A., Park, S.D.E., McGettigan, P.A., Lohan, A.J., Murphy, A., Finlay, E.K., (...), MacHugh, D.E., A complete mitochondrial genome sequence from a mesolithic wild aurochs (Bos primigenius), PLoS ONE, 5, (2), 2010, part. no. e9255
Downing T, Lloyd AT, O'Farrelly C, Bradley DG, The differential evolutionary dynamics of avian cytokine and TLR gene classes., Journal of immunology (Baltimore, Md. : 1950), 184, (12), 2010, p6993-7000
Laloë, D., Moazami-Goudarzi, K., Lenstra, J.A., Ajmone Marsan, P., Azor, P., Baumung, R., Bradley, D.G., (...), Wiener, P., Spatial trends of genetic variation of domestic ruminants in Europe, Diversity, 2, (6), 2010, p932-945
Murray, C., Huerta-Sanchez, E., Casey, F., Bradley, D.G., Cattle demographic history modelled from autosomal sequence variation, Philosophical Transactions of the Royal Society B: Biological Sciences, 365, (1552), 2010, p2531-2539
Downing, T, Lynn, DJ, Connell, S, Lloyd, AT, Bhuiyan, AF, Silva, P, Naqvi, AN, Sanfo, R, Sow, RS, Podisi, B, O'Farrelly, C, Hanotte, O, Bradley, DG, Contrasting evolution of diversity at two disease-associated chicken genes., Immunogenetics, 61, (1), 2009, p303 - 314
Kantanen J, Edwards CJ, Bradley DG, Viinalass H, Thessler S, Ivanova Z, Kiselyova T, Cinkulov M, Popov R, Stojanovi" S, Ammosov I, Vilkki J, Maternal and paternal genealogy of Eurasian taurine cattle (Bos taurus)., Heredity, 103, (5), 2009, p404-15
Downing, T., Lynn, D.J., Connell, S., Lloyd, A.T., Bhuiyan, A.K.F.H., Silva, P., Naqvi, A.N., (...), Bradley, D.G. , Erratum: Contrasting evolution of diversity at two disease-associated chicken genes (Immunogenetics DOI: 10.1007/s00251-009-0359-x), 2009, - 421-422
Stock, F., Edwards, C.J., Bollongino, R., Finlay, E.K., Burger, J., Bradley, D.G., Cytochrome b sequences of ancient cattle and wild ox support phylogenetic complexity in the ancient and modern bovine populations., Animal Genetics , 40, (5), 2009, p694-700
Cormican P, Lloyd AT, Downing T, Connell SJ, Bradley D, O'Farrelly C, The avian Toll-Like receptor pathway--subtle differences amidst general conformity., Developmental and comparative immunology, 33, (9), 2009, p967-73
Elsik CG, Tellam RL, Worley KC, Gibbs RA, Muzny DM, Weinstock GM, Adelson DL, Eichler EE, Elnitski L, Guigó R, Hamernik DL, Kappes SM, Lewin HA, Lynn DJ, Nicholas FW, Reymond A, Rijnkels M, Skow LC, Zdobnov EM, Schook L, Womack J, Alioto T, Antonarakis SE, Astashyn A, Chapple CE, Chen HC, Chrast J, Câmara F, Ermolaeva O, Henrichsen CN, Hlavina W, Kapustin Y, Kiryutin B, Kitts P, Kokocinski F, Landrum M, Maglott D, Pruitt K, Sapojnikov V, Searle SM, Solovyev V, Souvorov A, Ucla C, Wyss C, Anzola JM, Gerlach D, Elhaik E, Graur D, Reese JT, Edgar RC, McEwan JC, Payne GM, Raison JM, Junier T, Kriventseva EV, Eyras E, Plass M, Donthu R, Larkin DM, Reecy J, Yang MQ, Chen L, Cheng Z, Chitko-McKown CG, Liu GE, Matukumalli LK, Song J, Zhu B, Bradley DG, Brinkman FS, Lau LP, Whiteside MD, Walker A, Wheeler TT, Casey T, German JB, Lemay DG, Maqbool NJ, Molenaar AJ, Seo S, Stothard P, Baldwin CL, Baxter R, Brinkmeyer-Langford CL, Brown WC, Childers CP, Connelley T, Ellis SA, Fritz K, Glass EJ, Herzig CT, Iivanainen A, Lahmers KK, Bennett AK, Dickens CM, Gilbert JG, Hagen DE, Salih H, Aerts J, Caetano AR, Dalrymple B, Garcia JF, Gill CA, Hiendleder SG, Memili E, Spurlock D, Williams JL, Alexander L, Brownstein MJ, Guan L, Holt RA, Jones SJ, Marra MA, Moore R, Moore SS, Roberts A, Taniguchi M, Waterman RC, Chacko J, Chandrabose MM, Cree A, Dao MD, Dinh HH, Gabisi RA, Hines S, Hume J, Jhangiani SN, Joshi V, Kovar CL, Lewis LR, Liu YS, Lopez J, Morgan MB, Nguyen NB, Okwuonu GO, Ruiz SJ, Santibanez J, Wright RA, Buhay C, Ding Y, Dugan-Rocha S, Herdandez J, Holder M, Sabo A, Egan A, Goodell J, Wilczek-Boney K, Fowler GR, Hitchens ME, Lozado RJ, Moen C, Steffen D, Warren JT, Zhang J, Chiu R, Schein JE, Durbin KJ, Havlak P, Jiang H, Liu Y, Qin X, Ren Y, Shen Y, Song H, Bell SN, Davis C, Johnson AJ, Lee S, Nazareth LV, Patel BM, Pu LL, Vattathil S, Williams RL, Curry S, Hamilton C, Sodergren E, Wheeler DA, Barris W, Bennett GL, Eggen A, Green RD, Harhay GP, Hobbs M, Jann O, Keele JW, Kent MP, Lien S, McKay SD, McWilliam S, Ratnakumar A, Schnabel RD, Smith T, Snelling WM, Sonstegard TS, Stone RT, Sugimoto Y, Takasuga A, Taylor JF, Van Tassell CP, Macneil MD, Abatepaulo AR, Abbey CA, Ahola V, Almeida IG, Amadio AF, Anatriello E, Bahadue SM, Biase FH, Boldt CR, Carroll JA, Carvalho WA, Cervelatti EP, Chacko E, Chapin JE, Cheng Y, Choi J, Colley AJ, de Campos TA, De Donato M, Santos IK, de Oliveira CJ, Deobald H, Devinoy E, Donohue KE, Dovc P, Eberlein A, Fitzsimmons CJ, Franzin AM, Garcia GR, Genini S, Gladney CJ, Grant JR, Greaser ML, Green JA, Hadsell DL, Hakimov HA, Halgren R, Harrow JL, Hart EA, Hastings N, Hernandez M, Hu ZL, Ingham A, Iso-Touru T, Jamis C, Jensen K, Kapetis D, Kerr T, Khalil SS, Khatib H, Kolbehdari D, Kumar CG, Kumar D, Leach R, Lee JC, Li C, Logan KM, Malinverni R, Marques E, Martin WF, Martins NF, Maruyama SR, Mazza R, McLean KL, Medrano JF, Moreno BT, Moré DD, Muntean CT, Nandakumar HP, Nogueira MF, Olsaker I, Pant SD, Panzitta F, Pastor RC, Poli MA, Poslusny N, Rachagani S, Ranganathan S, Razpet A, Riggs PK, Rincon G, Rodriguez-Osorio N, Rodriguez-Zas SL, Romero NE, Rosenwald A, Sando L, Schmutz SM, Shen L, Sherman L, Southey BR, Lutzow YS, Sweedler JV, Tammen I, Telugu BP, Urbanski JM, Utsunomiya YT, Verschoor CP, Waardenberg AJ, Wang Z, Ward R, Weikard R, Welsh TH, White SN, Wilming LG, Wunderlich KR, Yang J, Zhao FQ, The genome sequence of taurine cattle: a window to ruminant biology and evolution., Science (New York, N.Y.), 324, (5926), 2009, p522-8
Cronin, S, Tomik, B, Bradley, DG, Slowik, A, Hardiman, O, Screening for replication of genome-wide SNP associations in sporadic ALS., European journal of human genetics : EJHG, 17, (2), 2009, p213 - 218
Gibbs RA, Taylor JF, Van Tassell CP, Barendse W, Eversole KA, Gill CA, Green RD, Hamernik DL, Kappes SM, Lien S, Matukumalli LK, McEwan JC, Nazareth LV, Schnabel RD, Weinstock GM, Wheeler DA, Ajmone-Marsan P, Boettcher PJ, Caetano AR, Garcia JF, Hanotte O, Mariani P, Skow LC, Sonstegard TS, Williams JL, Diallo B, Hailemariam L, Martinez ML, Morris CA, Silva LO, Spelman RJ, Mulatu W, Zhao K, Abbey CA, Agaba M, Araujo FR, Bunch RJ, Burton J, Gorni C, Olivier H, Harrison BE, Luff B, Machado MA, Mwakaya J, Plastow G, Sim W, Smith T, Thomas MB, Valentini A, Williams P, Womack J, Woolliams JA, Liu Y, Qin X, Worley KC, Gao C, Jiang H, Moore SS, Ren Y, Song XZ, Bustamante CD, Hernandez RD, Muzny DM, Patil S, San Lucas A, Fu Q, Kent MP, Vega R, Matukumalli A, McWilliam S, Sclep G, Bryc K, Choi J, Gao H, Grefenstette JJ, Murdoch B, Stella A, Villa-Angulo R, Wright M, Aerts J, Jann O, Negrini R, Goddard ME, Hayes BJ, Bradley DG, Barbosa da Silva M, Lau LP, Liu GE, Lynn DJ, Panzitta F, Dodds KG, Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds., Science (New York, N.Y.), 324, (5926), 2009, p528-32
Downing T, Cormican P, O'Farrelly C, Bradley DG, Lloyd AT, Evidence of the adaptive evolution of immune genes in chicken, BMC Research Notes, 2, (254), 2009, part. no. 254
Downing T, Lynn DJ, Connell S, Lloyd AT, Bhuiyan AK, Silva P, Naqvi AN, Sanfo R, Sow RS, Podisi B, Hanotte O, O'Farrelly C, Bradley DG, Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus., BMC Evolutionary Biology, 9, 2009, part. no. 136
Cronin, S, Berger, S, Ding, J, Schymick, JC, Washecka, N, Hernandez, DG, Greenway, MJ, Bradley, DG, Traynor, BJ, Hardiman, O, A genome-wide association study of sporadic ALS in a homogenous Irish population., Human molecular genetics, 17, (5), 2008, p768-74
McEvoy, B, Simms, K, Bradley, DG, Genetic investigation of the patrilineal kinship structure of early medieval Ireland., American journal of physical anthropology, 136, (4), 2008, p415-22
Cronin, S, Blauw, HM, Veldink, JH, van Es, MA, Ophoff, RA, Bradley, DG, van den Berg, LH, Hardiman, O, Analysis of genome-wide copy number variation in Irish and Dutch ALS populations., Human molecular genetics, 17, (21), 2008, p392-8
Freeman, AR, Lynn, DJ, Murray, C, Bradley, DG, Detecting the effects of selection at the population level in six bovine immune genes., BMC genetics, 9, 2008, p62
Sandilands, A, Terron-Kwiatkowski, A, Hull, PR, O'Regan, GM, Clayton, TH, Watson, RM, Carrick, T, Evans, AT, Liao, H, Zhao, Y, Campbell, LE, Schmuth, M, Gruber, R, Janecke, AR, Elias, PM, van Steensel, MA, Nagtzaam, I, van Geel, M, Steijlen, PM, Munro, CS, Bradley, DG, Palmer, CN, Smith, FJ, McLean, WH, Irvine, AD, Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema., Nature genetics, 39, (5), 2007, p650-4
Larson, G, Albarella, U, Dobney, K, Rowley-Conwy, P, Schibler, J, Tresset, A, Vigne, JD, Edwards, CJ, Schlumbaum, A, Dinu, A, Balaçsescu, A, Dolman, G, Tagliacozzo, A, Manaseryan, N, Miracle, P, Van Wijngaarden-Bakker, L, Masseti, M, Bradley, DG, Cooper, A, Ancient DNA, pig domestication, and the spread of the Neolithic into Europe., Proceedings of the National Academy of Sciences of the United States of America, 104, (39), 2007, p15276-81
Ancient DNA analysis of aurochsen in, editor(s)Alisdair Whittle , The early neolithic on the great Hungarian plain, Budapest, Instituti Archaeologici Academiae Scientairum Hungaricae, 2007, pp327 - 331, [Edwards CJ, Bradley DG]
Finlay, EK, Gaillard, C, Vahidi, SM, Mirhoseini, SZ, Jianlin, H, Qi, XB, El-Barody, MA, Baird, JF, Healy, BC, Bradley, DG, Bayesian inference of population expansions in domestic bovines., Biology letters, 3, (4), 2007, p449-52
Norton, HL, Kittles, RA, Parra, E, McKeigue, P, Mao, X, Cheng, K, Canfield, VA, Bradley, DG, McEvoy, B, Shriver, MD, Genetic evidence for the convergent evolution of light skin in Europeans and East Asians., Molecular biology and evolution, 24, (3), 2007, p710-22
Negrini, R, Nijman, IJ, Milanesi, E, Moazami-Goudarzi, K, Williams, JL, Erhardt, G, Dunner, S, Rodellar, C, Valentini, A, Bradley, DG, Olsaker, I, Kantanen, J, Ajmone-Marsan, P, Lenstra, JA, Differentiation of European cattle by AFLP fingerprinting., Animal genetics, 38, (1), 2007, p60-6
Cruz, F, Bradley, DG, Lynn, DJ, Evidence of positive selection on the Atlantic salmon CD3gammadelta gene., Immunogenetics, 59, (3), 2007, p225-32
Edwards, CJ, Bollongino, R, Scheu, A, Chamberlain, A, Tresset, A, Vigne, JD, Baird, JF, Larson, G, Ho, SY, Heupink, TH, Shapiro, B, Freeman, AR, Thomas, MG, Arbogast, RM, Arndt, B, Bartosiewicz, L, Benecke, N, Budja, M, Chaix, L, Choyke, AM, Coqueugniot, E, Döhle, HJ, Göldner, H, Hartz, S, Helmer, D, Herzig, B, Hongo, H, Mashkour, M, Ozdogan, M, Pucher, E, Roth, G, Schade-Lindig, S, Schmölcke, U, Schulting, RJ, Stephan, E, Uerpmann, HP, Vörös, I, Voytek, B, Bradley, DG, Burger, J, Mitochondrial DNA analysis shows a Near Eastern Neolithic origin for domestic cattle and no indication of domestication of European aurochs., Proceedings. Biological sciences / The Royal Society, 274, (1616), 2007, p1377-85
Bauchet, M, McEvoy, B, Pearson, LN, Quillen, EE, Sarkisian, T, Hovhannesyan, K, Deka, R, Bradley, DG, Shriver, MD, Measuring European population stratification with microarray genotype data., American journal of human genetics, 80, (5), 2007, p948-56
Lynn, DJ, Bradley, DG, Discovery of alpha-defensins in basal mammals., Developmental and comparative immunology, 31, (10), 2007, p963-7
Freeman AR, Hoggart CJ, Hanotte O, Bradley DG, Assessing the relative ages of admixture in the bovine hybrid zones of Africa and the Near East using X chromosome haplotype mosaicism., Genetics, 173, 2006, p1503-10
Freeman AR, Bradley DG, Nagda S, Gibson JP, Hanotte O, Combination of multiple microsatellite data sets to investigate genetic diversity and admixture of domestic cattle. Combination of multiple microsatellite data sets to investigate genetic diversity and admixture of domestic cattle. , Animal Genetics, 37, 2006, p1 - 9
Zeder MA, Bradley DG, Emshwiller E, Smith BD, Documenting Domestication: New Genetic and Archaeological Paradigms, Berkeley and Los Angeles, California, University of California Press, 2006
Documenting domestication: reading animal genetic texts in, editor(s)Zeder MA, Bradley DG, Emshwiller E and Smith BD , Documenting Domestication: New Genetic and Archaeological Paradigms, Berkeley and Los Angeles, California, University of California Press, 2006, pp273-278 , [Bradley DG]
Documenting domesitcation: bringing together plants, animals, archaeology and genetics. in, editor(s)Zeder MA, Bradley DG, Emshwiller E and Smith BD , Documenting Domestication: New Genetic and Archaeological Paradigms, Berkeley and Los Angeles, California, University of California Press, 2006, pp1-14 , [Zeder MA, Bradley DG, Emshwiller E and Smith BD]
Zeder MA, Emshwiller E, Smith BD, Bradley DG. , Documenting domestication: the intersection of genetics and archaeology., Trends in Genetics, 22, 2006, p139-55
Pereira F, Davis SJ, Pereira L, McEvoy B, Bradley DG, Amorim A. , Genetic signatures of a Mediterranean influence in Iberian Peninsula sheep husbandry., Molecular Biology and Evolution, 23, 2006, p1420-6
Bollongino R, Edwards CJ, Alt KW, Burger J, Bradley DG, Early history of European domestic cattle as revealed by ancient DNA, Biology Letters, 283, 2006, p155-159
McEvoy B, Brady C, Moore LT, Bradley DG, The scale and nature of Viking settlement in Ireland from Y-chromosome admixture analysis., European Journal of Human Genetics, 14, 2006, p1288-1294
McGahern AM, Edwards CJ, Bower MA, Heffernan A, Park SD, Brophy PO, Bradley DG, MacHugh DE, Hill EW, Mitochondrial DNA sequence diversity in extant Irish horse populations and in ancient horses, Animal Genetics, 37, 2006, p498-502
Moore LT, McEvoy B, Cape E, Simms K, Bradley DG., A Y-chromosome signature of hegemony in gaelic Ireland., American Journal of Human Genetics, 78, 2006, p334 - 338
Ryan AW, Mapp J, Moyna S, Mattiangeli V, Kelleher D, Bradley DG, McManus R, Levels of inter-population differentiation among different functional classes of immunologically important genes, Genes and Immunity, 7, (2), 2006, p179 - 183
McEvoy B, Bradley DG, Y-chromosomes and the extent of patrilineal ancestry in Irish surnames., Human Genetics, 119, 2006, p212-9
Genetics and origins of domestic cattle in, editor(s)Zeder MA, Bradley DG, Emshwiller E and Smith BD , Documenting Domestication: New Genetic and Archaeological Paradigms, Berkeley and Los Angeles, California, University of California Press, 2006, pp317-328 , [Bradley DG and Magee DA]
Ryan AW, Mapp J, Moyna S, Mattiangeli V, Kelleher D, Bradley DG, McManus R., Levels of interpopulation differentiation among different functional classes of immunologically important genes., Genes and Immunology, 7, 2006, p179 - 183
Mattiangeli V, Ryan AW, McManus R, Bradley DG. , A genome-wide approach to identify genetic loci with a signature of natural selection in the Irish population., Genome Biology, 11, 2006, pR74
Mattiangeli V, Ryan AW, McManus R, Bradley DG, A genome-wide approach to identify genetic loci with a signature of natural selection in the Irish population, Genome Biology, 7, (8), 2006, pR74-
Lynn DJ, Freeman AR, Murray C, Bradley DG., A genomics approach to the detection of positive selection in cattle: adaptive evolution of the T-cell and natural killer cell-surface protein CD2, Genetics, 170, 2005, p1189-96
Pereira F, Pereira L, Van Asch B, Bradley DG, Amorim A., The mtDNA catalogue of all Portuguese autochthonous goat (Capra hircus) breeds: high diversity of female lineages at the western fringe of European distribution., Molecular Ecology, 14, 2005, p2313-8
Gotherstrom A, Anderung C, Hellborg L, Elburg R, Smith C, Bradley DG, Ellegren H., Cattle domestication in the Near East was followed by hybridization with aurochs bulls in Europe., Proceedings of the Royal Society Series B, 22, 2005, p2337-44
Lister AM, Edwards CJ, Nock DA, Bunce M, van Pijlen IA, Bradley DG, Thomas MG, Barnes I., The phylogenetic position of the 'giant deer' Megaloceros giganteus., Nature, 438, 2005, p850 - 853
Pereira L, Richards M, Goios A, Alonso A, Albarran C, Garcia O, Behar DM, Golge M, Hatina J, Al-Gazali L, Bradley DG, Macaulay V, Amorim A., High-resolution mtDNA evidence for the late-glacial resettlement of Europe from an Iberian refugium., Genome Research, 15, 2005, p19 - 24
Götherström, A, Anderung, C, Hellborg, L, Elburg, R, Smith, C, Bradley, DG, Ellegren, H, Cattle domestication in the Near East was followed by hybridization with aurochs bulls in Europe., Proceedings. Biological sciences / The Royal Society, 272, (1579), 2005
Cymbron T, Freeman AR, Isabel Malheiro M, Vigne JD, Bradley DG., Microsatellite diversity suggests different histories for Mediterranean and Northern European cattle populations., Proceedings of the Royal Society Series B, 7, 2005, p1837-43
Pereira L, Richards M, Goios A, Alonso A, Albarran C, Garcia O, Behar DM, Golge M, Hatina J, Al-Gazali L, Bradley DG, Macaulay V, Amorim A., Evaluating the forensic informativeness of mtDNA haplogroup H sub-typing on a Eurasian scale., Forensic Science International, 159, 2005, p43 - 50
Dolan C, O'Halloran A, Bradley DG, Croke DT, Evans A, O'Brien JK, Dicker P, Shields DC., Genetic stratification of pathogen-response-related and other variants within a homogeneous Caucasian Irish population., European Journal of Human Genetics, 13, (7), 2005, p798 - 806
B. McEvoy, M. Richards, P. Forster and D. G. Bradley, The longue duree of genetic ancestry: multiple genetic marker systems and celtic origins on the atlantic facade of europe, American journal of human genetics, 75, (4), 2004, p693-702
Edwards C.J. MacHugh D.E., Dobney K.M., Martin L., Russell N., Horwitz L.K., McIntosh S.K., MacDonald K.C., Helmer D., Tresset A., Vigne J.-D. & Bradley D.G, Ancient DNA analysis of 101 cattle remains: limits and prospects, Journal of Archaeological Science, 31 (6) , (JUN), 2004, p695 - 710
Mannen H, Kohno, M., Nagata, Y., Tsuji, S., Bradley, D. G., Yeo, J. S., Nyamsamba, D., Zagdsuren, Y., Yokohama, M., Nomura, K. and Amano, T. , Independent Mitochondrial Origin and Historical Genetic Differentiation of North Eastern Asian Cattle, Molecular Phylogenetics and Evolution , 32 (2), (AUG), 2004, p539 - 544
O'Mahony EM, Bradley DG, Kennedy CR, Holland CV, Evidence for the hypothesis of strain formation in Pomphorhynchus laevis (Acanthocephala): an investigation using mitochondrial DNA sequences, PARASITOLOGY, 129: Part 3, (SEP), 2004, p341 - 347
Freeman AR, Meghen CM, Machugh DE, Loftus RT, Achukwi MD, Bado A, Sauveroche B, Bradley DG., Admixture and diversity in West African cattle populations., Molecular Ecology, 13, 2004, p3477-87
P. Kumar, A. R. Freeman, R. T. Loftus, C. Gaillard, D. Q. Fuller and D. G. Bradley, Admixture analysis of South Asian cattle, Heredity, 91, (1), 2003, p43-50
Bradley DG , Genetic hoofprints, Natural History , 112, 2003, p36 - 41
C. J. Edwards, J. Connellan, P. F. Wallace, S. D. Park, F. M. McCormick, I. Olsaker, E. Eythorsdottir, D. E. MacHugh, J. F. Bailey and D. G. Bradley, Feasibility and utility of microsatellite markers in archaeological cattle remains from a Viking Age settlement in Dublin, Animal genetics, 34, (6), 2003, p410-6
Bruford MW, Bradley DG and Luikart G, DNA markers reveal the complexity of livestock domestication, Nature Reviews Genetics , 4, 2003, p900 - 910
Beja-Pereira A, Luikart G, England PR, Bradley DG, Jann OC, Bertorelle G, Chamberlain AT, Nunes TP, Metodiev S, Ferrand N, Erhardt G., Gene-culture coevolution between cattle milk protein genes and human lactase genes, Nature Genetics, 35, 2003, p311 - 313
HANOTTE, O, AFRICAN PASTORALISM: GENETIC IMPRINTS OF ORIGINS AND MIGRATIONS, SCIENCE, 296, 2002, p336 - 339
HILL, EW, BRADLEY, DG, AL-BARODY, M, ERTUGRUL, O, SPLAN, RK, ZAKHAROV, I, CUNNINGHAM, EP, HISTORY AND INTEGRITY OF THOROUGHBRED DAM LINES REVEALED IN EQUINE MTDNA VARIATION, ANIMAL GENETICS, 33, 2002, p287 - 294
Genetic variation of mitochondrial DNA variation within domestic yak populations. in, editor(s)H Jianlin, C Richard, O. Hanotte, C McVeigh and JEO Rege. , Yak production in central Asian highlands, Nairobi, ILRI, 2002, pp181 - 189, [Bailey JF, Healy B, Jianlin H, Serchand L, Pradhan SL, Tsendsuren T, Foggin JM, Gaillard G, Steane D, Zakharov and Bradley DG]
Magee DA, Meghen C, Harrison S, Troy CS, Cymbron T, Gaillard C, Morrow A, Maillard JC and Bradley DG, A partial African ancestry for the Creole cattle populations of the Caribbean, Journal of Heredity , 93, 2002, p429 - 432
A. R. Freeman, D. E. MacHugh, S. McKeown, C. Walzer, D. J. McConnell and D. G. Bradley, Sequence variation in the mitochondrial DNA control region of wild African cheetahs (Acinonyx jubatus), Heredity, 86, (Pt 3), 2001, p355-62
C. S. Troy, D. E. MacHugh, J. F. Bailey, D. A. Magee, R. T. Loftus, P. Cunningham, A. T. Chamberlain, B. C. Sykes and D. G. Bradley, Genetic evidence for Near-Eastern origins of European cattle, Nature, 410, (6832), 2001, p1088-91
MacHugh DE, Bradley DG., Livestock genetic origins: goats buck the trend., Proceedings of the National Academy of Sciences, USA, 98, 2001, p5382-4
E. P. Cunningham, J. J. Dooley, R. K. Splan and D. G. Bradley, Microsatellite diversity, pedigree relatedness and the contributions of founder lineages to thoroughbred horses, Animal genetics, 32, (6), 2001, p360-4
LOFTUS, RT, ERTUGRUL, O, HARBA, AH, EL-BARODY, MAA, MACHUGH, DE, PARK, SDE, BRADLEY, DG, A MICROSATELLITE SURVEY OF CATTLE FROM A CENTRE OF ORIGIN: THE NEAR EAST, MOLECULAR ECOLOGY, 8, 2000, p2015 - 2022
Y chromosomes and Irish origins in, editor(s)Renfrew, C.A. & Boyle, K , Archaeogenetics: DNA and the population prehistory of Europe, Cambridge, UK, McDonald Institute Monographs, 2000, ppChapter 22 , [Hill EW, Jobling MA & Bradley DG]
E. W. Hill, M. A. Jobling and D. G. Bradley, Y-chromosome variation and Irish origins, Nature, 404, (6776), 2000, p351-2
C. J. Edwards, C. Gaillard, D. G. Bradley and D. E. MacHugh, Y-specific microsatellite polymorphisms in a range of bovid species, Animal genetics, 31, (2), 2000, p127-30
HANOTTE, O, TAWAH, CL, BRADLEY, DG, OKOMO, M, VERJEE, Y, OCHIENG, J, REGE, JEO, GEOGRAPHIC DISTRIBUTION AND FREQUENCY OF A TAURINE BOS TAURUS AND AN INDICINE BOS INDICUS Y SPECIFIC ALLELE AMONGST SUB-SAHARAN AFRICAN CATTLE BREEDS, MOLECULAR ECOLOGY, 9, 2000, p387 - 396
NORRIS, AT, BRADLEY, DG, CUNNINGHAM, EP, PARENTAGE AND RELATEDNESS DETERMINATION IN FARMED ATLANTIC SALMON (SALMO SALAR) USING MICROSATELLITE MARKERS, AQUACULTURE, 182, 2000, p73 - 83
C. J. Edwards, G. Dolf, C. Looft, R. T. Loftus and D. G. Bradley, Relationships between the endangered Pustertaler-Sprinzen and three related European cattle breeds as analysed with 20 microsatellite loci, Animal genetics, 31, (5), 2000, p329-32
HELGASON, A, SIGUROARDOTTIR, S, NICHOLSON, J, SYKES, B, HILL, EW, BRADLEY, DG, BOSNES, V, GULCHER, JR, WARD, R, STEFANSSON, K, ESTIMATING SCANDINAVIAN AND GAELIC ANCESTRY IN THE MALE SETTLERS OF ICELAND, AMERICAN JOURNAL OF HUMAN GENETICS, 67, 2000, p697 - 717
ROSSER, ZH, ZERJAL, T, HURLES, ME, ADOJAAN, M, ALAVANTIC, D, AMORIM, A, AMOS, W, ARMENTEROS, M, ARROYO, E, BARBUJANI, G, BECKMAN, G, BECKMAN, L, BERTRANPETIT, J, BOSCH, E, BRADLEY, DG, BREDE, G, COOPER, G, CORTE-REAL, HBSM, DE KNIJFF, P, DECORTE, R, DUBROVA, YE, EVGRAFOV, O, GILISSEN, A, GLISIC, S, GOLGE, M, HILL, EW, JEZIOROWSKA, A, KALAYDJIEVA, L, KAYSER, M, KIVISILD, T, KRAVCHENKO, SA, KRUMINA, A, KUCINSKAS, V, LAVINHA, J, LIVSHITS, LA, MALASPINA, P, MARIA, S, MCELREAVEY, K, MEITINGER, TA, MIKELSAAR, AV, MITCHELL, RJ, NAFA, K, NICHOLSON, J, NORBY, S, PANDYA, A, PARIK, J, PATSALIS, PC, PEREIRA, L, PETERLIN, B, PIELBERG, G, PRATA, ML, PREVIDERE, C, ROEWER, L, ROOTSI, S, RUBINSZTEIN, DC, SAILLARD, J, SANTOS, FR, STEFANESCU, G, SYKES, BC, TOLUN, A, VILLEMS, R, TYLER-SMITH, C, JOBLING, MA, Y-CHROMOSOMAL DIVERSITY IN EUROPE IS CLINAL AND INFLUENCED PRIMARILY BY GEOGRAPHY, RATHER THAN BY LANGUAGE, AMERICAN JOURNAL OF HUMAN GENETICS, 67, 2000, p1526 - 1543
Richards M, Macaulay V, Hickey E, Vega E, Sykes B, Guida V, Rengo C, Sellitto D, Cruciani F, Kivisild T, Villems R, Thomas M, Rychkov S, Rychkov O, Rychkov Y, Golge M, Dimitrov D, Hill E, Bradley D, Romano V, Cali F, Vona G, Demaine A, Papiha S, Triantaphyllidis C & Stefanescu G. , Tracing European founder lineages in the Near Eastern mtDNA pool, American Journal of Human Genetics, 67, (5), 2000, p125 - 1276
Mitochondrial DNA diversity and the origins of domestic livestock in Archaeogenetics: DNA and the population history of Europe. in, editor(s)C. Renfrew and K Boyle , McDonald Institute Monographs., 2000, [Bradley DG ]
Systematics and phylogeny of cattle in, editor(s)R Fries and A Ruvinsky , The genetics of cattle, Wallingford, UK., CAB International, 1999, [Lenstra, J. A. and Bradley, D. G.]
Characterisation of the Kuri cattle of Lake Chad using molecular genetic techniques in, editor(s).M. Blench and K.C. MacDonald , Origin and Development of African livestock, UCL Press, 1999, [Meghen, C, MacHugh DE, Sauveroche B, Kana G, Bradley DG]
NORRIS, AT, BRADLEY, DG, CUNNINGHAM, EP, MICROSATELLITE GENETIC VARIATION BETWEEN AND WITHIN FARMED AND WILD ATLANTIC SALMON (SALMO SALAR) POPULATIONS, AQUACULTURE, 180, 1999, p247 - 264
CYMBRON, T, LOFTUS, RT, MALHEIRO, MI, BRADLEY, DG, MITOCHONDRIAL SEQUENCE VARIATION SUGGESTS AN AFRICAN INFLUENCE IN PORTUGUESE CATTLE, PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, 266, 1999, p597 - 603
R. T. Loftus, O. Ertugrul, A. H. Harba, M. A. El-Barody, D. E. MacHugh, S. D. Park and D. G. Bradley, A microsatellite survey of cattle from a centre of origin: the Near East, Molecular ecology, 8, (12), 1999, p2015-22
MACHUGH, DE, TROY, CS, MCCORMICK, F, OLSAKER, I, EYTHORSDOTTIR, E, BRADLEY, DG, EARLY MEDIEVAL CATTLE REMAINS FROM A SCANDINAVIAN SETTLEMENT IN DUBLIN: GENETIC ANALYSIS AND COMPARISON WITH EXTANT BREEDS, PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, 354, 1999, p99 - 108
D. E. MacHugh, C. S. Troy, F. McCormick, I. Olsaker, E. Eythorsdottir and D. G. Bradley, Early medieval cattle remains from a Scandinavian settlement in Dublin: genetic analysis and comparison with extant breeds, Philosophical transactions of the Royal Society of London Series B, Biological sciences, 354, (1379), 1999, p99-108; discussion 108-9
PARK, SDE, ADOMEFA, K, DAO, B, HANOTTE, O, KEMP, SJ, SOW, R, TEALE, AJ, BRADLEY, DG, APPLICATION OF POPULATION GENETIC ANALYSIS OF LINKED, MAPPED MICROSATELLITES TO THE IDENTIFICATION OF LOCI UNDER SELECTION FOR DISEASE RESISTANCE, ARCHIV FUR TIERZUCHT-ARCHIVES OF ANIMAL BREEDING, 42, 1999, p97 - 99
NIJMAN, IJ, BRADLEY, DG, HANOTTE, O, OTSEN, M, LENSTRA, JA, SATELLITE DNA POLYMORPHISMS AND AFLP CORRELATE WITH BOS INDICUS-TAURUS HYBRIDIZATION, ANIMAL GENETICS, 30, 1999, p265 - 273
Genetic aspects of domestication, common breeds and their origins in, editor(s)R Fries and A Ruvinsky , The genetics of cattle, Wallingford, UK, CAB International, 1999, [Bradley, DG and Cunningham P]
BRADLEY, DG, LOFTUS, RT, CUNNINGHAM, P, MACHUGH, DE, GENETICS AND DOMESTIC CATTLE ORIGINS, EVOLUTIONARY ANTHROPOLOGY, 6, 1998, p79 - 86
ACHUKWI, MD, TANYA, VN, HILL, EW, BRADLEY, DG, MEGHEN, C, SAUVEROCHE, B, BANSER, JT, NDOKI, JN, SUSCEPTIBILITY OF THE NAMCHI AND KAPSIKI CATTLE OF CAMEROON TO TRYPANOSOME INFECTION, TROPICAL ANIMAL HEALTH AND PRODUCTION, 29, 1998, p219 - 226
MANNEN, H, TSUJI, S, LOFTUS, RT, BRADLEY, DG, MITOCHONDRIAL DNA VARIATION AND EVOLUTION OF JAPANESE BLACK CATTLE (BOS TAURUS), GENETICS, 150, 1998, p1169 - 1175
D. E. MacHugh, R. T. Loftus, P. Cunningham and D. G. Bradley, Genetic structure of seven European cattle breeds assessed using 20 microsatellite markers, Animal genetics, 29, (5), 1998, p333-40
D. E. MacHugh, M. D. Shriver, R. T. Loftus, P. Cunningham and D. G. Bradley, Microsatellite DNA variation and the evolution, domestication and phylogeography of taurine and zebu cattle (Bos taurus and Bos indicus), Genetics, 146, (3), 1997, p1071-86
D. G. Bradley, D. E. MacHugh, P. Cunningham and R. T. Loftus, Mitochondrial diversity and the origins of African and European cattle, Proceedings of the National Academy of Sciences of the United States of America, 93, (10), 1996, p5131-5
BAILEY, JF, RICHARDS, MB, MACAULAY, VA, COLSON, IB, JAMES, IT, BRADLEY, DG, HEDGES, REM, SYKES, BC, ANCIENT DNA SUGGESTS A RECENT EXPANSION OF EUROPEAN CATTLE FROM A DIVERSE WILD PROGENITOR SPECIES, PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, 263, 1996, p1467 - 1473
HALL, SJG, BRADLEY, DG, CONSERVING LIVESTOCK BREED BIODIVERSITY, TRENDS IN ECOLOGY & EVOLUTION, 10, 1995
Meghen, C., MacHugh, D.E. and Bradley, D.G. , Genetic Chracterisation and West African Cattle, World Animal Review., 78, 1994, p59 - 66
R. T. Loftus, D. E. MacHugh, D. G. Bradley, P. M. Sharp and P. Cunningham, Evidence for two independent domestications of cattle, Proceedings of the National Academy of Sciences of the United States of America, 91, (7), 1994, p2757-61
D. G. Bradley, D. E. MacHugh, R. T. Loftus, R. S. Sow, C. H. Hoste and E. P. Cunningham, Zebu-taurine variation in Y chromosomal DNA: a sensitive assay for genetic introgression in west African trypanotolerant cattle populations, Animal genetics, 25, (1), 1994, p07-Dec
D. E. Machugh, R. T. Loftus, D. G. Bradley, P. M. Sharp and P. Cunningham, Microsatellite DNA variation within and among European cattle breeds, Proceedings of the Royal Society of London Series B Biological sciences, 256, (1345), 1994, p25-31
R. T. Loftus, D. E. MacHugh, L. O. Ngere, D. S. Balain, A. M. Badi, D. G. Bradley and E. P. Cunningham, Mitochondrial genetic variation in European, African and Indian cattle populations, Animal genetics, 25, (4), 1994, p265-71
HEALY, JMS, HEFFRON, JJA, LEHANE, M, BRADLEY, DG, JOHNSON, K, MCCARTHY, TV, DIAGNOSIS OF SUSCEPTIBILITY TO MALIGNANT HYPERTHERMIA WITH FLANKING DNA MARKERS, BRITISH MEDICAL JOURNAL, 303, 1991, p1225 - 1228
R. Kumar-Singh, D. G. Bradley, G. J. Farrar, M. Lawler, S. A. Jordan and P. Humphries, Autosomal dominant retinitis pigmentosa: a new multi-allelic marker (D3S621) genetically linked to the disease locus (RP4), Human genetics, 86, (5), 1991, p502-4
M. M. Humphries, D. Sheils, M. Lawler, G. J. Farrar, P. McWilliam, P. Kenna, D. G. Bradley, E. M. Sharp, E. F. Gaffney, M. Young and et al., Epidermolysis bullosa: evidence for linkage to genetic markers on chromosome 1 in a family with the autosomal dominant simplex form, Genomics, 7, (3), 1990, p377-81
G. J. Farrar, P. McWilliam, D. G. Bradley, P. Kenna, M. Lawler, E. M. Sharp, M. M. Humphries, H. Eiberg, P. M. Conneally, J. A. Trofatter and et al., Autosomal dominant retinitis pigmentosa: linkage to rhodopsin and evidence for genetic heterogeneity, Genomics, 8, (1), 1990, p35-40
G. J. Farrar, P. Kenna, R. Redmond, P. McWilliam, D. G. Bradley, M. M. Humphries, E. M. Sharp, C. F. Inglehearn, R. Bashir, M. Jay and et al., Autosomal dominant retinitis pigmentosa: absence of the rhodopsin proline----histidine substitution (codon 23) in pedigrees from Europe, American journal of human genetics, 47, (6), 1990, p941-5
D. G. Bradley, G. J. Farrar, E. M. Sharp, P. Kenna, M. M. Humphries, D. J. McConnell, S. P. Daiger, P. McWilliam and P. Humphries, Autosomal dominant retinitis pigmentosa: exclusion of the gene from the short arm of chromosome 1 including the region surrounding the rhesus locus, American journal of human genetics, 44, (4), 1989, p570-6
G. J. Farrar, P. McWilliam, E. M. Sharp, P. Kenna, D. G. Bradley, M. M. Humphries, D. J. McConnell and P. Humphries, Autosomal dominant retinitis pigmentosa: exclusion of a gene from extensive regions of chromosomes 6, 13, 20, and 21, Genomics, 5, (3), 1989, p612-8
Daiger S P, Humphries M M, Giesenschlag N, Sharp E M, McWilliam P, Farrar G J, Bradley D G, McConnell D J, Kenna P, Sparkes R S, Spence M A, Heckenlively J R and Humphries P , Linkage analysis of human chromosome 4: exclusion of autosomal dominant retinitis pigmentosa and detection of new linkage groups, Cytogenetics. and Cell Genetics, 50, 1989, p181 - 187
P. McWilliam, G. J. Farrar, P. Kenna, D. G. Bradley, M. M. Humphries, E. M. Sharp, D. J. McConnell, M. Lawler, D. Sheils, C. Ryan and et al., Autosomal dominant retinitis pigmentosa (ADRP): localization of an ADRP gene to the long arm of chromosome 3, Genomics, 5, (3), 1989, p619-22
Non-Peer-Reviewed Publications
Oxen, Grolier Encyclopedia New Book of Knowledge, 2003, [Bradley DG ]
Bradley DG and Hill EW, Whats in a surname, Archaeology Ireland , 14, 2000, p22 - 23
Designing life: the role of inheritance in, editor(s)M. Jumker-Kenny , Designing life? Genetics, procreation and ethics, Aldershot, Ashgate Publishing Ltd, 1999, [Bradley DG]
Loftus R.T., D.E. MacHugh, P. Cunningham and D.G. Bradley, Animal domestication [letter], Science, 283, 1999, p329-30
Loftus RT, D.G. Bradley, D.E. MacHugh, C.S. Troy, C.N. Meghen and E.P. Cunningham , Molecular genetics and the evolution of domesticated cattle, 8th World Conference on Animal Production, 1, 1998, pp144 - 145
Meghen, C. N., Scott, C. S., Bradley, D. G., MacHugh, D. E., Loftus, R. T. and Cunningham, E. P. , DNA based traceability for the meat industry, 8th World Conference on Animal Production, 1998, pp774 - 775
Bradley, DG and O'Sullivan, M., Tracing our ancient ancestors., Archaeology Ireland , 39, 1997, p18 - 20
McHugh, D. E., Loftus, R. T., Troy, C. S. and Bradley, D. G. , DNA Analysis and the origins and history of domesticated cattle, Archaeology of Southwest Asia (ASWA) conference, Budapest, 1996
Bradley, D. G., Loftus, R. T., MacHugh, D. E. and Cunningham, P., The Molecular Evolution of Domestic cattle, Symposium on Mediterranean Animal Germplasm and Future Human Challenges, Salerno, 1996
Cunningham, E. P., Loftus, R. T., MacHugh, D. E., Bradley, D. G., Molecular evolution of African, European and Asian Cattle, 21, 5th World Congress on Genetics Applied to Livestock Production, 1994, pp86 - 89
An integrated global programme to establish the genetic relationships among the breeds of each domestic animal species in, Report of a working group, Rome, FAO , 1993, [Barker JSF, Bradley DG, Fries R, Hill WG, Nei M, and Wayne RK]
Bradley, DG, MacHugh, DE, Loftus, RT, Meghen, C, Sharp, PM, Cunningham, EP, ) Genetic Characterisation of Indigenous Cattle Breeds: First Results and Implications for Genetic Improvement, FAO Animal Production and Health Paper , 110, 1993, p37 - 45
Bradley, D. G, Genetic characterisation of cattle breeds in West and Central Africa, Trypanotolerant Livestock Newsletter , 5, 1992, p3 - 8
Research Expertise
Description
I have active research in: ancient genomic analysis of western European humans, particularly Irish archaeological remains; ancient genomes of cattle sheep and goat.Projects
- Title
- AncestralWeave: 1000 ancient genomes: gene-economy innovation in cattle, sheep and goat
- Summary
- The genetic threads of goat, cattle and sheep ancestry have been woven by human breeding, environmental pressures, hybridisation and the chance effects of genetic drift. The ancestral weaves of these key animals intertwine with human creativity in the most profoundly innovative episodes of the human past. Three broad episodes of particular import were: initial domestications circa 11 kya in Southwest Asia; the intensification circa 6 kya of use of those animal products which are harvested without killing such as wool, milk and traction; and the development of exceptionally productive landraces, later formalized into breeds, in recent millennia. However, each of these is loosely defined in time and space, the key traits are often osteologically invisible, and the vectors of causality in their virtuous cycles of gene-economy innovation are completely unknown. A combination of high coverage ancient whole genome data coupled with new analysis methods that allow efficient computation of genomewide locus genealogies will be used to untangle the threads of ancestry in sheep, cattle and goat across the whole genome in these transformative phases. Combining these with additional low coverage genomes generated from less preserved samples will generate a total set of 1,000 ancient animal genomes. These data will be unprecedented and will allow tracking of selection at trait genes, in order to detect human agency in breeding and, in collaboration with archaeologist partners, asking are there periods and places where threads of innovation coalesce. The project will also use ancient epigenetics to explore archaeological variation in gene activation patterns and will seek to understand the problematic build up of harmful mutations that threaten livestock today. With cognate disciplines, it will compare signals of animal mobility identifying distinct genetic strata correlating with archaeological horizons and affording the prospect of DNA-dating in future excavation.
- Funding Agency
- European Research Council
- Date From
- December 2020
- Date To
- November 2025
Recognition
Representations
Member of a Wellcome Trust Panel responsible for the disbursement of research funds in Bioarchaeology
Appointed to Editorial Board of the international journal, Animal Genetics
Five times juror in the European Contest for Young Scientists
Member of the Royal Irish Academy Advisory Committee on Genetic Anthropology
Served as an expert consultant on genetic distance and biodiversity to the Food and Agriculture Organisation of the United Nations
Member, PHG Funded PI's and Researchers, All Researchers funded under Cycle 3 PRTLI - Programme for Human Genomics
Awards and Honours
TCD Fellowship
CGIAR award for outstanding scientific article
Member of the Royal Irish Academy
Royal Irish Academy Gold Medal in the Life Sciences
Memberships
Member of International Society of Animal Genetics
former President of Irish Society of Human Genetics