Professor Conleth Feighery
Fellow Emeritus, Fellows Emeritii
Publications and Further Research Outputs
Peer-Reviewed Publications
Hogan PC, O'Connell RM, Scollard S, Browne E, Hackett EE, Feighery C, Biomarkers Predict Relapse in Granulomatosis with Polyangiitis., Journal of biomarkers, 2014, 2014, p596503
Cooper,Suzanne E J S.E.J., Kennedy,Nicholas P. N.P., Mohamed,Bashir Mustafa B.M., Abuzakouk,Mohamed M., Dunne,Jean J., Byrne,Greg G., McDonald,George S A G.S.A., Davies,Anthony Mitchell A.M., Edwards,Connla C., Kelly,Jacinta D. J.D., Feighery,Conleth F. C.F., Immunological indicators of coeliac disease activity are not altered by long-term oats challenge, Clinical and Experimental Immunology, 171, (3), 2013, p313-318
O'Reilly V, Zeng SG, Bricard G, Atzberger A, Hogan AE, Jackson J, Feighery C, Porcelli SA, Doherty DG, Distinct and Overlapping Effector Functions of Expanded Human CD4, CD8α and CD4CD8α Invariant Natural Killer T Cells, PloS one, 6, (12, e28648), 2011
Brophy K*, Ryan AW*, Turner G, Trimble V, Patel KD, O'Morain C, Kennedy NP, Egan B, Close E, Lawlor G, MacMathuna P, Stevens FM, Abuzakouk M, Feighery C, Kelleher D, McManus R, Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study, BMC Medical Genetics, 11, (76), 2010
Feighery CF, McManus R., Symposium on 'The challenge of translating nutrition research into public health nutrition'. Session 3: Joint Nutrition Society and Irish Nutrition and Dietetic Institute Symposium on 'Nutrition and autoimmune disease'. Recent advances in genetic understanding of coeliac disease. , Proceedings of the Nutrition Society, 68, (2), 2009, p122-126
Bracken S, Bryne G, Kelly J, Jackson J, Feighery C , Altered gene expression in highly purified enterocytes from patients with active coeliac disease , BMC Genomics, 8, (9), 2008, p377-
Mohamed BM, Feighery C, Coates C, O'Shea U, Delaney D, O'Briain S, Kelly J, Abuzakouk M. , The absence of a mucosal lesion on standard histological examination does not exclude diagnosis of celiac disease , Digestive Disease Science , 52, (1), 2008, p52 - 61
Healy C, Abuzakouk M, Feighery C, Flint S, Acquired angioedema in non-Hodgkin's lymphoma, Oral Surgery Oral Medicine Oral Pathology Oral Radiology Endodontics, 103, 2007, p29 - 32
Doyle SL, Jefferies CA, Feighery C, O'Neill LA., Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase., Journal of Biological Chemistry, 282, (51), 2007, p36953-36960.
van Heel DA, Franke L, Hunt KA, Gwilliam R, Zhernakova A, Inouye M, Wapenaar MC, Barnardo MC, Bethel G, Holmes G, FEIGHERY C, et al. , A genome-wide association study of celiac disease identifies risk variants in the region harboring IL2 and IL21 , Nature Genetics , 39, (7), 2007, p827 - 829
van Heel DA, Franke L, Hunt KA, Gwilliam R, Zhernakova A, Inouye M, Wapenaar MC, Barnardo MC, Bethel G, Holmes GK, Feighery C, Jewell D, Kelleher D, Kumar P, Travis S, Walters JR, Sanders DS, Howdle P, Swift J, Playford RJ, McLaren WM, Mearin ML, Mulder CJ, McManus R, McGinnis R, Cardon LR, , A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21., Nature Genetics, 39, (7), 2007, p827 - 829
Oral Surg Oral Med Oral Pathol Oral Radiol Endo, 103, 5, (2007), 29 - 32p, Healy C, Abuzakouk M, Feighery C, Flint S, [eds.]
Doyle SL, Jefferies CA, Feighery C, O'Neill LA , Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosne kinase , Journal of Biological Chemistry, 282, (51), 2007, p36953 - 36960
Feighery LM, Smith P, O'Mahony L, Fallon PG, Brayden DJ., Effects of Lactobacillus salivarius 433118 on intestinal inflammation, immunity status and in vitro colon function in two mouse models of inflammatory bowel disease., Digestive Diseases and Sciences, 53, (9), 2007, p2495 - 2506
Abuzakouk M, Barnes L, O'Gorman N, O'Grady A, Mohamed B, McKenna MJ, Freaney R, Feighery C, Dermatitis Herpetiformis: No Evidence of Bone Disease Despite Evidence of Enteropathy, Digestive Disease Science, 52, (3), 2007, p659 - 664
Williams Y, Byrne G, Lynch S, Feighery C, Abuzakouk M, Type II Hereditary Angioedema-Presenting as Food Allergy , Digestive Disease Science, 52, (2), 2007, p353 - 356
Feighery C, Conlon N, Jackson J, Adult population screening for coeliac disease: comparison of tissue-transglutaminase antibody and anti-endomysial antibody tests, European Journal of Gastroenterology & Hepatology , 18, (11), 2006, p1173 - 1175
Daly A, Walsh C, Feighery C, O'Shea U, Jackson J, Whelan A, Serum levels of soluble CD163 correlate with the inflammatory process in coeliac disease, Aliment Pharmacol Ther , 24, (3), 2006, p553 - 559
Daly A, Walsh C, Feighery C, O'Shea U, Jackson J, Whelan A, Serum levels of soluble CD163 correlate with the inflammatory process in coeliac disease, Aliment Pharmacol Ther , 24, (3), 2006, p553 - 559
Eidenschenk C, Dunne J, Jouanguy E, Fourlinnie C, Gineau L, Bacq D, McMahon C, Smith O, Casanova JL, Abel L, Feighery C, A novel primary immunodeficiency with specific natural-killer cell deficiency maps to the centromeric region of chromosome 8, American Journal Human Genet, 78, (4), 2006, p721 - 727
Brophy K, Ryan AW, Thornton JM, Daly JS, McLoughlin R, O' Morain C, Abuzakouk M, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R, Haplotypes in the CTLA4 region are associated with coeliac disease in the Irish population., Genes and Immunity, 7, (1), 2006, p19 - 26
Kilmartin C, Wieser H, Abuzakouk M, Kelly J, Jackson J, Feighery C, Intestinal T cell responses to cereal proteins in celiac disease, Digestive Disease Science , 51, (1), 2006, p202 - 209
Brophy K, Ryan AW, Thornton JM, Abuzakouk M, Fitzgerald AP, McLoughlin RM, O'Morain C, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R., Haplotypes in the CTLA4 region are associated with coeliac disease in the Irish population, Genes Immunol, 7, (1), 2006, p19 - 26
Lin F, Murphy R, White B, Kelly J, Feighery C, Doyle R, Pittock S, Moroney J, Smith O, Livingstone W, Keenan C, Jackson J, Circulating levels of beta2-glycoprotein I in thrombotic disorders and in inflammation, LUPUS, 15, (2), 2006, p87 - 93
Mohamed BM, Feighery C, Kelly J, Coates C, O'Shea U, Barnes L, Abuzakouk M, Increased protein expression of matrix metalloproteinases -1, -3, and -9 and TIMP-1 in patients with gluten-sensitive enteropathy, Digestive Disease Science , 51, (10), 2006, p1862 - 1868
Bracken SC, Kilmartin C, Wieser H, Jackson J, Feighery C, Barley and rye prolamins induce an mRNA interferon-gamma response in coeliac mucosa, Aliment Pharmacol Ther , 23, (9), 2006, p1307 - 1314
Byrne G, Ryan F, Jackson J, Feighery C, Kelly J, Mutagenesis of the catalytic triad of tissue transglutaminase abrogates coeliac disease serum IgA autoantibody binding, GUT , 53, 2006, p336 - 341
Srinivasan U, Jones E, Carolan J, Feighery C, Immunohistochemical analysis of coeliac mucosa following ingestion of oats, Clinical Experimental Immunology , 144, (2), 2006, p197 - 203
Ryan AW, Thornton JM, Brophy K, Daly JS, McLoughlin RM, O'Morain C, Abuzakouk M, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R, Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1, Tissue Antigens, 65, (2), 2005, p150 - 155
De Groot K, Rasmussen N, Bacon PA, Tervaert JW, Feighery C, Gregorini G, Gross WL, Luqmani R, Jayne DR, Randomized trial of cyclophosphamide versus methotrexate for induction of remission in early systemic antineutrophil cytoplasmic antibody-associated vasculitis, Arthritis Rheumatology , 52, (8), 2005, p2461 - 2469
Ryan AW, Thornton JM, Brophy K, Daly JS, McLoughlin RM, O'Morain C, Abuzakouk M, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R, Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1, Tissue Antigens, 65, (2), 2005, p150 - 155
Ryan AW, Thornton JM, Brophy K, Daly JS, McLoughlin RM, O' Morain C, Abuzakouk M, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R., Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1., Tissue Antigens, 65, (2), 2005, p150 - 155
Abuzakouk M, Feighery C, Primary immunodeficiency disorders in the Republic of Ireland: first report of the national registry in children and adults, Journal of Clinical Immunology , 25, (1), 2005, p73 - 77
A. W. Ryan, J. M. Thornton, K. Brophy, J. S. Daly, C. O'Morain, R. M. McLoughlin, N. P. Kennedy, M. Abuzakouk, F. M. Stevens, C. Feighery, D. Kelleher and R. McManus, Haplotype variation at the IBD5/SLC22A4 locus (5q31) in coeliac disease in the Irish population, Tissue antigens, 64, (2), 2004, p195-8
Ryan AW, Thornton JM, Brophy K, Daly JS, O' Morain C, McLoughlin RM, Kennedy NP, Abuzakouk M, Stevens FM, Feighery C, Kelleher D, McManus R. , Haplotype variation at the IBD5 locus (5q31) in coeliac disease in the Irish population. , Tissue Antigens, 64, (2), 2004, p195 - 198
Feighery L, Collins C, Feighery C, Mahmud N, Coughlan G, Willoughby R, Jackson J, Anti-transglutaminase antibodies and the serological diagnosis of coeliac disease, British Journal of Biomedical Science, 60, 2003, p14 - 18
Feighery C, O'Keefe J, TNF-alpha production by intraepithelial T cells in celiac disease, Gastroenterology, 125, 2003, p1560 - 1561
F. Lin, C. Feighery, J. Guerin, H. O'Byrne and J. Jackson, Enzyme-linked immunosorbent assay for beta2-glycoprotein I quantitation: the importance of variability in the plastic support, British journal of biomedical science, 60, (3), 2003, p165-8
Williams Y, Feighery C, Abuzakouk M, C1q autoantibodies: cause or effect of recurrent infection, LUPUS, 12, 2003, p795 - 797
Abuzakouk M, Feighery C, Jackson J, Tumour necrosis factor blocking agents: a new therapeutic modality for inflammatory disorders, British Journal of Biomedical Science , 59, 2002, p173 - 179
Aganna E, Martinon F, Hawkins PN, Ross JB, Swan DC, Booth DR, Lachmann HJ, Bybee A, Gaudet R, Woo P, Feighery C, Cotter FE, Thome M, Hitman GA, Tschopp J, McDermott MF, Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis, Arthritis Rheumatology , 46, 2002, p2445 - 2452
O'Leary C, Feighery C, Feighery A, Quane K, Shanahan F, Molloy M, Cronin CC. , The prevalence of coeliac disease among female subjects having bone densitometry , Irish Journal of Medical Science , 171, (3), 2002, p145 - 147
B. Byrne, L. Madrigal-Estebas, A. McEvoy, J. Carton, D. G. Doherty, A. Whelan, C. Feighery, D. P. O'Donoghue and C. O'Farrelly, Human duodenal epithelial cells constitutively express molecular components of antigen presentation but not costimulatory molecules, Human immunology, 63, (11), 2002, p977-86
L. Madrigal-Estebas, D. G. Doherty, D. P. O'Donoghue, C. Feighery and C. O'Farrelly, Differential expression and upregulation of interleukin-1alpha, interleukin-1beta and interleukin-6 by freshly isolated human small intestinal epithelial cells, Mediators of inflammation, 11, (5), 2002, p313-9
J. Dunne, S. Lynch, C. O'Farrelly, S. Todryk, J. E. Hegarty, C. Feighery and D. G. Doherty, Selective expansion and partial activation of human NK cells and NK receptor-positive T cells by IL-2 and IL-15, Journal of immunology (Baltimore, Md, 167, (6), 2001, p3129-38
J. O'Keeffe, S. Lynch, A. Whelan, J. Jackson, N. P. Kennedy, D. G. Weir and C. Feighery, Flow cytometric measurement of intracellular migration inhibition factor and tumour necrosis factor alpha in the mucosa of patients with coeliac disease, Clinical and experimental immunology, 125, (3), 2001, p376-82
M. Abuzakouk, C. Feighery, D. Kelleher, D. S. O'Briain, E. Jones, D. Weir, E. Casey and C. O'Farrelly, Increased HLA-DR and CD44 antigen expression in the gut: evidence of extraarticular immunological activity in rheumatoid arthritis, The Journal of rheumatology, 26, (9), 1999, p1869-76
U. Srinivasan, D. G. Weir, C. Feighery and C. O'Farrelly, Emergence of classic enteropathy after longstanding gluten sensitive oral ulceration, BMJ (Clinical research ed), 316, (7126), 1998, p206-7
C. Feighery, M. Abuzakouk, C. Liddy, J. Jackson, A. Whelan, R. Willougby, C. Cronin and D. S. Kumararatne, Endomysial antibody detection using human umbilical cord tissue as substrate: reactivity of cells in Wharton's jelly, British journal of biomedical science, 55, (2), 1998, p107-10
C. Feighery, D. G. Weir, A. Whelan, R. Willoughby, S. Youngprapakorn, S. Lynch, C. O'Morain, P. McEneany and C. O'Farrelly, Diagnosis of gluten-sensitive enteropathy: is exclusive reliance on histology appropriate?, European journal of gastroenterology & hepatology, 10, (11), 1998, p919-25
M. Abuzakouk, J. Carton, C. Feighery, D. P. O'Donoghue, D. G. Weir and C. O'Farrelly, CD4+ CD8+ and CD8alpha+ beta- T lymphocytes in human small intestinal lamina propria, European journal of gastroenterology & hepatology, 10, (4), 1998, p325-9
J. Guerin, O. Smith, B. White, G. Sweetman, C. Feighery and J. Jackson, Antibodies to prothrombin in antiphospholipid syndrome and inflammatory disorders, British journal of haematology, 102, (4), 1998, p896-902
C. Feighery, A. Whelan and D. G. Weir, Endomysium: autoantigen in coeliac disease, European journal of gastroenterology & hepatology, 9, (7), 1997, p655-6
L. Madrigal-Estebas, R. McManus, B. Byrne, S. Lynch, D. G. Doherty, D. Kelleher, D. P. O'Donoghue, C. Feighery and C. O'Farrelly, Human small intestinal epithelial cells secrete interleukin-7 and differentially express two different interleukin-7 mRNA Transcripts: implications for extrathymic T-cell differentiation, Human immunology, 58, (2), 1997, p83-90
L. Madrigal-Estebas, R. McManus, B. Byrne, S. Lynch, D. G. Doherty, D. Kelleher, D. P. O'Donoghue, C. Feighery and C. O'Farrelly, Human small intestinal epithelial cells secrete interleukin-7 and differentially express two different interleukin-7 mRNA Transcripts: implications for extrathymic T-cell differentiation, Human Immunology, 58, (2), 1997, p83-90
J. Hassan, G. Yanni, V. Hegarty, C. Feighery, B. Bresnihan and A. Whelan, Increased numbers of CD5+ B cells and T cell receptor (TCR) gamma delta+ T cells are associated with younger age of onset in rheumatoid arthritis (RA), Clinical and experimental immunology, 103, (3), 1996, p353-6
U. Srinivasan, N. Leonard, E. Jones, D. D. Kasarda, D. G. Weir, C. O'Farrelly and C. Feighery, Absence of oats toxicity in adult coeliac disease, BMJ (Clinical research ed), 313, (7068), 1996, p1300-1
M. Abuzakouk, C. Feighery and C. O'Farrelly, Collagenase and Dispase enzymes disrupt lymphocyte surface molecules, Journal of immunological methods, 194, (2), 1996, p211-6
M. Abuzakouk, D. Kelleher, C. Feighery and C. O'Farrelly, Increased HLA-DR and decreased CD3 on human intestinal intraepithelial lymphocytes: evidence of activation?, Gut, 39, (3), 1996, p396-400
J. V. Reynolds, C. O'Farrelly, C. Feighery, P. Murchan, N. Leonard, G. Fulton, C. O'Morain, F. B. Keane and W. A. Tanner, Impaired gut barrier function in malnourished patients, The British journal of surgery, 83, (9), 1996, p1288-91
E. Corrigan, D. Kelleher, C. Feighery and A. Long, Protein kinase C isoform expression in CD45RA+ and CD45RO+ T lymphocytes, Immunology, 85, (2), 1995, p299-303
D. Kelleher, A. Murphy, C. Feighery and E. B. Casey, Leukocyte function-associated antigen 1 (LFA-1) and CD44 are signalling molecules for cytoskeleton-dependent morphological changes in activated T cells, Journal of leukocyte biology, 58, (5), 1995, p539-46
G. Yanni, A. Whelan, C. Feighery and B. Bresnihan, Synovial tissue macrophages and joint erosion in rheumatoid arthritis, Annals of the rheumatic diseases, 53, (1), 1994, p39-44
J. Hassan, C. Feighery, B. Bresnihan, M. Keogan, M. X. Fitzgerald and A. Whelan, Serum IgA and IgG subclasses during treatment for acute respiratory exacerbation in cystic fibrosis: analysis of patients colonised with mucoid or non-mucoid strains of pseudomonas aeruginosa, Immunological investigations, 23, (1), 1994, pJan-13
M. Callaghan, A. Whelan, C. Feighery and B. Bresnihan, IL-2 enhances polyclonal IgM but not IgM-rheumatoid factor synthesis by activated human peripheral blood B cells, Clinical and experimental immunology, 93, (2), 1993, p212-7
G. Yanni, A. Whelan, C. Feighery, O. Fitzgerald and B. Bresnihan, Morphometric analysis of synovial membrane blood vessels in rheumatoid arthritis: associations with the immunohistologic features, synovial fluid cytokine levels and the clinical course, The Journal of rheumatology, 20, (4), 1993, p634-8
A. Murphy, K. C. Breen, A. Long, C. Feighery, E. B. Casey and D. Kelleher, Neurofilament expression in human T lymphocytes, Immunology, 79, (1), 1993, p167-170
L. Madrigal, S. Lynch, C. Feighery, D. Weir, D. Kelleher and C. O'Farrelly, Flow cytometric analysis of surface major histocompatibility complex class II expression on human epithelial cells prepared from small intestinal biopsies, Journal of immunological methods, 158, (2), 1993, p207-14
A. Murphy, K. C. Breen, A. Long, C. Feighery, E. B. Casey and D. Kelleher, Neurofilament expression in human T lymphocytes, Immunology, 79, (1), 1993, p167-70
G. Yanni, A. Whelan, C. Feighery, W. Quinlan, J. Symons, G. Duff and B. Bresnihan, Contrasting levels of in vitro cytokine production by rheumatoid synovial tissues demonstrating different patterns of mononuclear cell infiltration, Clinical and experimental immunology, 93, (3), 1993, p387-95
M. T. Keogan, M. Callaghan, G. Yanni, D. Mulherin, C. Feighery, D. L. Brown, M. X. Fitzgerald and B. Bresnihan, Spontaneous in vitro production of rheumatoid factor during infectious exacerbations of cystic fibrosis: correlation with circulating immune complex levels, Clinical and experimental immunology, 91, (3), 1993, p462-6
J. Hassan, C. Feighery, B. Bresnihan and A. Whelan, Prevalence of anti-Fab antibodies in patients with autoimmune and infectious diseases, Clinical and experimental immunology, 89, (3), 1992, p423-6
G. Yanni, A. Whelan, C. Feighery and B. Bresnihan, Analysis of cell populations in rheumatoid arthritis synovial tissues, Seminars in arthritis and rheumatism, 21, (6), 1992, p393-9
D. G. Quinn, J. S. Fennell, O. Sheils, E. F. Gaffney and C. F. Feighery, Effect of cyclosporin on immune complex deposition in murine glomerulonephritis, Immunology, 72, (4), 1991, p550-4
J. Hassan, A. Whelan, B. Bresnihan and C. Feighery, Induction of IgM and IgM-rheumatoid factor synthesis in vitro by indomethacin, Rheumatology international, 10, (6), 1991, p235-9
J. Hassan, C. Feighery, B. Bresnihan and A. Whelan, Effect of gold therapy on CD5+ B-cells and TCR gamma delta+ T-cells in patients with rheumatoid arthritis, Rheumatology international, 11, (04-May), 1991, p175-8
C. O'Farrelly, C. O'Mahony, F. Graeme-Cook, C. Feighery, B. E. McCartan and D. G. Weir, Gliadin antibodies identify gluten-sensitive oral ulceration in the absence of villous atrophy, Journal of oral pathology & medicine, 20, (10), 1991, p476-8
M. Soden, M. Rooney, A. Whelan, C. Feighery and B. Bresnihan, Immunohistological analysis of the synovial membrane: search for predictors of the clinical course in rheumatoid arthritis, Annals of the rheumatic diseases, 50, (10), 1991, p673-6
J. Hassan, C. Feighery, B. Bresnihan and A. Whelan, Elevated T cell receptor gamma delta + T cells in patients with infectious mononucleosis, British journal of haematology, 77, (2), 1991, p255-6
D. Kelleher, C. Feighery and D. G. Weir, Chemiluminescence by polymorphonuclear leucocyte subpopulations in chronic inflammatory bowel disease. Influence of the cell separation procedure, Digestion, 45, (3), 1990, p158-65
J. Hassan, C. Feighery, B. Bresnihan and A. Whelan, Increased CD5+ B cells in infectious mononucleosis, British journal of haematology, 74, (3), 1990, p375-6
M. Soden, A. Whelan, C. Feighery and B. Bresnihan, Lymphocyte infiltration and the synthesis of IgM and IgA rheumatoid factors by rheumatoid synovial membrane, Rheumatology international, 10, (4), 1990, p149-52
M. Rooney, A. Whelan, C. Feighery and B. Bresnihan, Changes in lymphocyte infiltration of the synovial membrane and the clinical course of rheumatoid arthritis, Arthritis and rheumatism, 32, (4), 1989, p361-9
J. Hassan, C. Feighery, B. Bresnihan and A. Whelan, Expression and regulation of the HLA-DR antigen on circulating monocytes isolated from patients with rheumatoid arthritis, Arthritis and rheumatism, 32, (6), 1989, p682-90
M. Soden, J. Hassan, D. L. Scott, J. G. Hanly, M. Moriarty, A. Whelan, C. Feighery and B. Bresnihan, Lymphoid irradiation in intractable rheumatoid arthritis. Long-term followup of patients treated with 750 rads or 2,000 rads, Arthritis and rheumatism, 32, (5), 1989, p523-30
M. Coffey, J. Hassan, C. Feighery, M. Fitzgerald and B. Bresnihan, Rheumatoid factors in cystic fibrosis: associations with disease manifestations and recurrent bacterial infections, Clinical and experimental immunology, 77, (1), 1989, p52-7
M. Soden, M. Rooney, A. Cullen, A. Whelan, C. Feighery and B. Bresnihan, Immunohistological features in the synovium obtained from clinically uninvolved knee joints of patients with rheumatoid arthritis, British journal of rheumatology, 28, (4), 1989, p287-92
M. Rooney, A. Whelan, C. Feighery and B. Bresnihan, The immunohistologic features of synovitis, disease activity and in vitro IgM rheumatoid factor synthesis by blood mononuclear cells in rheumatoid arthritis, The Journal of rheumatology, 16, (4), 1989, p459-67
P. A. McCormick, C. Feighery, C. Dolan, C. O'Farrelly, P. Kelliher, F. Graeme-Cook, A. Finch, K. Ward, M. X. Fitzgerald, D. P. O'Donoghue and et al., Altered gastrointestinal immune response in sarcoidosis, Gut, 29, (12), 1988, p1628-31
P. Rogers, J. Hassan, B. Bresnihan, C. Feighery and A. Whelan, Antibodies to Proteus in rheumatoid arthritis, British journal of rheumatology, 27 Suppl 2, 1988, p90-4
M. Rooney, D. Condell, W. Quinlan, L. Daly, A. Whelan, C. Feighery and B. Bresnihan, Analysis of the histologic variation of synovitis in rheumatoid arthritis, Arthritis and rheumatism, 31, (8), 1988, p956-63
C. O'Farrelly, F. Graeme-Cook, D. O. Hourihane, C. Feighery and D. G. Weir, Histological changes associated with wheat protein antibodies in the absence of villous atrophy, Journal of clinical pathology, 40, (10), 1987, p1228-30
J. Kelly, C. O'Farrelly, C. O'Mahony, D. G. Weir and C. Feighery, Immunoperoxidase demonstration of the cellular composition of the normal and coeliac small bowel, Clinical and experimental immunology, 68, (1), 1987, p177-88
K. Mealy, C. O'Farrelly, R. Stephens and C. Feighery, Impaired neutrophil function during anesthesia and surgery is due to serum factors, The Journal of surgical research, 43, (5), 1987, p393-7
J. Hassan, C. Feighery, B. Bresnihan and A. Whelan, Characterization and quantification of solubilised HLA-DR antigens from circulating human monocytes using an immunoblotting procedure, Tissue antigens, 30, (4), 1987, p167-75
J. Kelly, C. O'Farrelly, J. P. Rees, C. Feighery and D. G. Weir, Humoral response to alpha gliadin as serological screening test for coeliac disease, Archives of disease in childhood, 62, (5), 1987, p469-73
J. G. Hanly, J. Hassan, A. Whelan, C. Feighery and B. Bresnihan, Effects of gold therapy on the synthesis and quantity of serum and synovial fluid IgM, IgG, and IgA rheumatoid factors in rheumatoid arthritis patients, Arthritis and rheumatism, 29, (4), 1986, p480-7
J. Hassan, J. Hanly, B. Bresnihan, C. Feighery and C. A. Whelan, The immunological consequences of gold therapy: a prospective study in patients with rheumatoid arthritis, Clinical and experimental immunology, 63, (3), 1986, p614-20
J. G. Hanly, J. Hassan, M. Moriarty, C. Barry, J. Molony, E. Casey, A. Whelan, C. Feighery and B. Bresnihan, Lymphoid irradiation in intractable rheumatoid arthritis. A double-blind, randomized study comparing 750-rad treatment with 2,000-rad treatment, Arthritis and rheumatism, 29, (1), 1986, p16-25
C. O'Farrelly, C. Feighery, D. S. O'Briain, F. Stevens, C. E. Connolly, C. McCarthy and D. G. Weir, Humoral response to wheat protein in patients with coeliac disease and enteropathy associated T cell lymphoma, British medical journal (Clinical research ed), 293, (6552), 1986, p908-10
D. Kelleher, F. J. Bloomfield, T. Lenehan, M. Griffin, C. Feighery, and S. R. McCann, Chronic granulomatous disease presenting as an oculomucocutaneous syndrome mimicking Behçet's syndrome, Postgraduate Medical Journal, 62, (728), 1986, p489 - 491
J. Kelly, C. O'Farrelly, J. P. Rees, C. F. Feighery and D. G. Weir, Alpha-gliadin antibodies in childhood coeliac disease, Lancet, 2, (8454), 1985, p558-9
J. G. Hanly, J. Hassan, M. Moriarty, A. Whelan, C. Feighery and B. Bresnihan, Lymphoid irradiation in intractable rheumatoid arthritis: effects on the production of immunoglobulins and rheumatoid factors, Clinical and experimental immunology, 62, (3), 1985, p647-56
C. O'Farrelly, J. Kelly, C. Feighery, J. P. Rees, H. Monaghan, E. Tempany and D. G. Weir, Coeliac disease, Irish medical journal, 78, (10), 1985, p299
C. O'Farrelly, C. A. Whelan, C. F. Feighery and D. G. Weir, Suppressor-cell activity in coeliac disease induced by alpha-gliadin, a dietary antigen, Lancet, 2, (8415), 1984, p1305-7
C. O'Farrelly, U. McKeever, C. Feighery and D. G. Weir, Increased concanavalin A induced suppression in treated and untreated coeliac disease, Gut, 25, (6), 1984, p644-8
C. O'Farrelly, J. Kelly, W. Hekkens, B. Bradley, A. Thompson, C. Feighery and D. G. Weir, Alpha gliadin antibody levels: a serological test for coeliac disease, British medical journal (Clinical research ed), 286, (6383), 1983, p2007-10
C. O'Farrelly, W. T. Hekkens, C. Feighery and D. G. Weir, The specificity of wheat protein reactivity in coeliac disease, Scandinavian journal of gastroenterology, 18, (5), 1983, p603-7
C. O'Farrelly, C. Feighery, J. F. Greally and D. G. Weir, Cellular response to alpha-gliadin in untreated coeliac disease, Gut, 23, (1), 1982, p83-7
Research Expertise
Description
Since my appointment as Consultant Immunologist to St. James's Hospital and the former Federated Dublin Voluntary Hospitals (now Tallaght or AMNiCH hospital), I developed clinical and research interests in the following areas: . PRIMARY IMMUNODEFICIENCY DISORDERS . AUTOIMMUNE DISORDERS, IN PARTICULAR CONNECTIVE TISSUE DISEASES . WEGENER'S GRANULOMATOSIS . COELIAC DISEASE. Since 1982, a busy clinical and laboratory Immunology service has evolved. The laboratory currently performs investigations on some 80,000 specimens per annum. A busy outpatient and daycare facility was established. In excess of 60 patients with primary immunodeficiency states attend the clinic and a home based therapy has been developed for patients with immunoglobulin deficiency states. Research has focused in particular on auto-immune disorders, with coeliac disease as the principal interest. However, research into other disorders including primary immunodeficiency states also continues.Recognition
Representations
Copy, Inflammatory Lung Disease, Proposed workshop on inflammatory diseases of the lung.Includes clinicians presenting on their specific disease type to fundamental scientists.Objectives :To build links between fundamental and clinican scientistsTo look for opportunities for trans-institutional collaborationTo connect senior post-docs (emerging PI's) with clinician counterpart