Skip to main content

Trinity College Dublin, The University of Dublin

Trinity Menu Trinity Search

You are here People

Dr. Michelle Armstrong
Assistant Professor, Clinical Medicine

Publications and Further Research Outputs

Peer-Reviewed Publications

Dunbar H, Hawthorne IJ, Tunstead C, Armstrong ME, Donnelly SC, English K., Blockade of MIF biological activity ameliorates house dust mite-induced allergic airway inflammation in humanized MIF mice., The FASEB Journal , 37, 2023, pe23072- Journal Article, 2023

Shin JJ, Fan W, Par-Young J, Piecychna M, Leng L, Israni-Winger K, Qing H, Gu J, Zhao H, Schulz WL, Unlu S, Kuster J, Young G, Liu J, Ko AI, Baeza Garcia A, Sauler M, Wisnewski AV, Young L, Orduña A, Wang A, Klementina O, Garcia AB, Hegyi P, Armstrong ME, Mitchell P, Ordiz DB, Garami A, Kang I, Bucala R., MIF is a Common Genetic Determinant of COVID-19 Symptomatic Infection and Severity., QJM the Quarterly Journal of Medicine, 116, (3), 2023, p205 - 212 Journal Article, 2023 URL

Nano-Based Therapies for Acute and Chronic Lung Diseases in, editor(s)Ribeiro de Araujo, D., Carneiro-Ramos, M. , Biotechnology Applied to Inflammatory Diseases - Cellular Mechanisms and Nanomedicine,, Springer, Singapore, 2023, [Doroudian M, Armstrong ME, Donnelly SC.] Book Chapter, 2023

McElroy AN, Invernizzi R, Laskowska JW, O'Neill A, Doroudian M, Moghoofei M, Mostafaei S, Li F, Przybylski AA, O'Dwyer DN, Bowie AG, Fallon PG, Maher TM, Hogaboam CM, Molyneaux PL, Hirani N, Armstrong ME, Donnelly SC., Candidate Role for Toll-like Receptor 3 L412F Polymorphism and Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis., American journal of respiratory and critical care medicine, 2022 Journal Article, 2022 DOI

Vancheri C, Luppi F. , Editorial: Identifying the Risk of Acute Exacerbation in Idiopathic Pulmonary Fibrosis: A Step Forward., American Journal of Respiratory and Critical Care Medicine, 205, (5), 2022, p489 - 491. Journal Article, 2022 URL

Moghoofei M, Mostafaei S, Kondori N, Armstrong ME, Babaei F., Bacterial and viral coinfection in idiopathic pulmonary fibrosis patients: the prevalence and possible role in disease progression, BMC Pulm Med ., 22, (1), 2022, p60 - 67 Journal Article, 2022 URL

Doroudian M and O'Neill A, O'Reilly C, Tynan A, Mawhinney, L, McElroy AN, Webster SS, Macloughlin R, Volkov Y, Armstrong ME, O'Toole GA, Prina-Mello A, Donnelly SC., Aerosolized drug-loaded nanoparticles targeting migration inhibitory factors inhibit Pseudomonas aeruginosa induced inflammation and biofilm formation, Nanomedicine, 15, (30), 2020, p2933-2953 Journal Article, 2020 DOI

Mostafaei S, Vahidi Manesh P, Sadri Nahand J, Nesaei A, Sorayyayi S, Abasabadi F, Mirzaei H, Etemadi A, O' Neill A, Donnelly SC, Doroudian M, Armstrong ME, Moghoofei M., The role of Epstein-Barr virus-expressed genes in breast cancer development, The breast journal, 26, (11), 2020, p2323 - 2326 Journal Article, 2020 URL

Moore C, Blumhagen RZ, Yang IV, Walts A. et al., Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis., American Journal of Respiratory and Critical Care Medicine, 200, (2), 2019, p199 - 208 Journal Article, 2019

Cooke G, Kamal I, Strengert M, Hams E, Mawhinney L, Tynan A, O' Reilly C, O' Dwyer DN, Kunkel SL, Knaus UG, Shields DC, Moller DR, Bowie AG, Fallon PG, Hogaboam CM, Armstrong ME, Donnelly SC., Toll-like receptor 3 L412F polymorphism promotes a persistent clinical phenotype in pulmonary sarcoidosis., QJM, 2018, p217-224 Journal Article, 2018 TARA - Full Text URL

Mostafaei S, Kazemnejad A, Azimzadeh Jamalkandi S, Amirhashchi S, Donnelly SC, Armstrong ME, Doroudian M., Identification of Novel Genes in Human Airway Epithelial Cells associated with Chronic Obstructive Pulmonary Disease (COPD) using Machine-Based Learning Algorithms., Sci. Rep., 8, (1), 2018, p15775- Journal Article, 2018 URL

Tynan A, Mawhinney L, Armstrong ME, O'Reilly C, Kennedy S, Caraher E, Jülicher K, O'Dwyer D, Maher L, Schaffer K, Fabre A, McKone EF, Leng L, Bucala R, Bernhagen J, Cooke G, Donnelly SC., Macrophage migration inhibitory factor enhances Pseudomonas aeruginosa biofilm formation, potentially contributing to cystic fibrosis pathogenesis., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31, (11), 2017, p5102-5110 Journal Article, 2017 DOI

O'Dwyer DN, Armstrong ME, Kooblall M, Donnelly SC, Targeting defective Toll-like receptor-3 function and idiopathic pulmonary fibrosis., Expert Opin Ther Targets ., 2015 Journal Article, 2015

Mawhinney L, Armstrong ME, O' Reilly C, Bucala R, Leng L, Fingerle-Rowson G, Fayne D, Keane MP, Tynan A, Maher L, Cooke G, Lloyd D, Conroy H, Donnelly SC, Macrophage migration inhibitory factor (MIF) enzymatic activity and lung cancer., Molecular medicine, 20, (1), 2014, p729 - 735 Journal Article, 2014

Hams E, Armstrong ME, Barlow JL, Saunders SP, Schwartz C, Cooke G, Fahy RJ, Crotty TB, Hirani N, Flynn RJ, Voehringer D, McKenzie AN, Donnelly SC, Fallon PG, IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis., Proceedings of the National Academy of Sciences of the United States of America, 111, (1), 2014, p367-72 Journal Article, 2014 TARA - Full Text DOI

Rea IM, McNerlan SE, Alexander DH, Armstrong ME., Blood pressure and TNF-" act synergistically to increase leucocyte CD11b adhesion molecule expression in the BELFAST study: implications for better blood pressure control in ageing., Age (Dordrecht, Netherlands), 35, (1), 2013, p197-205 Journal Article, 2013 DOI

O'Dwyer DN, Armstrong ME, Trujillo G, Cooke G, Keane MP, Fallon PG, Simpson AJ, Millar AB, McGrath EE, Whyte MK, Hirani N, Hogaboam CM, Donnelly SC., The Toll-like receptor 3 L412F polymorphism and disease progression in idiopathic pulmonary fibrosis., Am J Respir Crit Care Med., 188, 2013, p1442 - 1450 Journal Article, 2013 DOI

Cooke G, Govender P, Watson CJ, Armstrong ME, O'Dwyer DN, Keane MP, King R, Tynan A, Dunn M, Donnelly SC, Sarcoidosis, alveolar ß-actin and pulmonary fibrosis., QJM, 2013 Journal Article, 2013

O'Dwyer DN, Armstrong ME, Cooke G, Dodd JD, Veale DJ, Donnelly SC, Rheumatoid Arthritis (RA) associated interstitial lung disease (ILD)., Eur J Intern Med., 2013 Journal Article, 2013

MIF and Pulmonary Disease in, The MIF Handbook (1st Edition; Editor: Richard Bucala), World Scientific Publishing Company., 2012, [Cooke G, Armstrong ME, Conroy H and Donnelly SC] Book Chapter, 2012

Adamali H, Armstrong ME, McLaughlin AM, Cooke G, McKone E, Costello CM, Gallagher CG, Leng L, Baugh JA, Fingerle-Rowson G, Bucala RJ, McLoughlin P, Donnelly SC, Macrophage migration inhibitory factor enzymatic activity, lung inflammation, and cystic fibrosis., Am J Respir Crit Care Med., 186, (2), 2012, p162 - 169 Journal Article, 2012

Cooke G, Armstrong ME, Donnelly SC, Macrophage migration inhibitory factor (MIF), enzymatic activity and the inflammatory response., BIOFACTORS, 2009 Journal Article, 2009

Costelloe C, Watson M, Murphy A, McQuillan K, Loscher C, Armstrong ME,, IL-1F5 mediates anti-inflammatory activity in the brain through induction, J Neurochem, 105, (5), 2008, p1960-1969 Journal Article, 2008 DOI URL

Armstrong ME, Gantier M, Li L, Chung WY, McCann A, Baugh JA, Donnelly SC, Small interfering RNAs induce macrophage migration inhibitory factor production and proliferation in breast cancer cells via a double-stranded RNA-dependent protein kinase-dependent mechanism., J Immunol., 2008 Journal Article, 2008

Armstrong ME, Lavelle EC, Loscher CE, Lynch MA, Mills KHG, Proinflammatory Responses in the Murine Brain after Intranasal Delivery of Cholera Toxin: Implications for the Use of AB Toxins as Adjuvants in Intranasal Vaccines, Journal of Infectious Diseases, 192, (9), 2005, p1628 - 1633 Journal Article, 2005 TARA - Full Text

Lavelle EC, Jarnicki A, McNeela E, Armstrong ME, Higgins SC, Leavy O, Mills KHG, Effects of cholera toxin on innate and adaptive immunity and its application as an immunomodulatory agent, Journal of Leukocyte Biology, 75, (5), 2004, p756 - 763 Journal Article, 2004 TARA - Full Text DOI

Lavelle EC, McNeela E, Armstrong ME, Leavy O, Higgins SC, Mills KH., Cholera toxin promotes the induction of regulatory T cells specific for bystander antigens by modulating dendritic cell activation., Journal of immunology (Baltimore, Md. : 1950), 171, (5), 2003, p2384-2392 Journal Article, 2003 DOI

Armstrong, M.E., Loscher, C.E., Lynch, M.A. and Mills, K.H.G., IL-1beta-dependent neurological effects of the whole cell pertussis vaccine: a role for IL-1-associated signalling components in vaccine reactogenicity, J. Neuroimmunol., 136, (1-2), 2003, p25 - 33 Journal Article, 2003 DOI URL

Armstrong ME, Alexander HD, Ritchie JL, McMillan SA, Rea IM., Age-related alterations in basal expression and in vitro, tumour necrosis factor alpha mediated, upregulation of CD11b., Gerontology, 47, (4), 2001, p180-185 Journal Article, 2001 DOI