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Dr. Oliviero Gobbo
Assistant Professor, Pharmacy

Biography

Dr Oliviero Gobbo is a pharmaceutical scientist at Trinity College Dublin, where he also completed his PhD. He has over 25 years of experience in academic research, as well as experience in the pharmaceutical industry, where he was involved in the development of novel therapeutics for traumatic brain injury (TBI) and eating disorders. This combination of academic and industry experience provides him with a strong translational perspective on drug discovery, development and delivery. His research focuses on nanomedicine and innovative drug delivery approaches, with particular interests in brain and lung cancer, neuropharmacology, obesity and the development of therapies for challenging diseases. His work integrates pharmaceutical sciences, nanotechnology, pharmacology, imaging and preclinical research, using models including rodents and zebrafish to investigate disease mechanisms, drug efficacy, safety and delivery. In 2023-2024, Dr Gobbo was a Visiting Academic at NYU Abu Dhabi, where he contributed to research and international academic collaboration. Since January 2026, Dr Gobbo has served as Director of Equality, Equity, Diversity and Inclusion within the School of Pharmacy and Pharmaceutical Sciences, supporting the development of an inclusive and equitable environment for staff and students. Dr Gobbo is also committed to advancing neuro-oncology in Ireland. He co-founded the Irish Neuro-Oncology Society (INOS) and currently serves as its President, promoting collaboration, education and advocacy across the Irish neuro-oncology community.

Publications and Further Research Outputs

Peer-Reviewed Publications

Selo M.A., Gobbo O.L., Obaidi I., O'Connor C., Fayne D., Armstrong M.E., Donnelly S.C., Bridging Inflammation and Oncology: The Role and Therapeutic Potential of Macrophage Migration Inhibitory Factor in Lung Cancer, International Journal of Molecular Sciences, 27, (6), 2026 Review, 2026 TARA - Full Text DOI

Anna Laurenzana, Martin Albino, Giorgia Papini, Cecilia Anceschi, Elena Balica, Alessio Gabbani, Claudia Innocenti, Francesca Scavone, Francesca Margheri, Lisa Giovanelli, Danièle Bani, Oliviero L. Gobbo, Mario Del Rosso, Claudio Sangregorio, Magneto-Mechanical Nanotherapy for Adiposopathy: Targeting Lipid Metabolism and Inflammation, 2025 Preprint, 2025 DOI

Alanazi A., Craven A., Spirou S.V., Santos-Martinez M.J., Medina C., Gobbo O.L., Nanomedicine as a Promising Treatment Approach for Obesity, Journal of Nanotheranostics, 6, (3), 2025 Review, 2025 DOI

Mundzic M., Ultimo A., Mladenovic M., Pavlovic A., Gobbo O.L., Ruiz-Hernandez E., Santos-Martinez M.J., Knezevic N.Z., Chlorotoxin-functionalized mesoporous silica nanoparticles for pH-responsive paclitaxel delivery to Glioblastoma multiforme, Heliyon, 11, (1), 2025 Journal Article, 2025 DOI

Abughalia A., Flynn M., Clarke P.F.A., Fayne D., Gobbo O.L., The Use of Computational Approaches to Design Nanodelivery Systems, Nanomaterials, 15, (17), 2025 Review, 2025 DOI

Gobbo O.L., Tackling obesity from a nanomedicine perspective, Review of Clinical Pharmacology and Pharmacokinetics, International Edition, 38, 2024, p15 - 17, p15-17 Journal Article, 2024 DOI

Mundzic M., Lazovic J., Mladenovic M., Pavlovic A., Ultimo A., Gobbo O.L., Ruiz-Hernandez E., Santos-Martinez M.J., Knezevic N.Z., MRI-based sensing of pH-responsive content release from mesoporous silica nanoparticles, Journal of Sol-Gel Science and Technology, 111, (1), 2024, p95 - 105, p95-105 Journal Article, 2024 DOI

Alanezi, S.T. and Almutairi, W.M. and Cronin, M. and Gobbo, O. and O'Mara, S.M. and Sheppard, D. and O'Connor, W.T. and Gilchrist, M.D. and Kleefeld, C. and Colgan, N., Whole-brain traumatic controlled cortical impact to the left frontal lobe: Magnetic resonance image-based texture analysis, Journal of Neuropathology and Experimental Neurology, 83, (2), 2024, p94-106 Journal Article, 2024 DOI

LCS Erthal, Y Shi, KJ Sweeney, OL Gobbo, E Ruiz-Hernandez, Nanocomposite formulation for a sustained release of free drug and drug-loaded responsive nanoparticles: an approach for a local therapy of glioblastoma multiforme, Scientific Reports, 13, (1), 2023, p5094- Journal Article, 2023 DOI

Hannon, G. and Bogdanska, A. and Keogh, A. and Finn, S.P. and Gobbo, O.L. and Prina-Mello, A., Biodistribution and histological analysis of iron oxide-dextran nanoparticles in wistar rats, Nanotoxicology, 17, (8-9), 2023, p562-580 Journal Article, 2023 DOI

Fernandez, Y. and Movellan, J. and Foradada, L. and Gimenez, V. and Garcia-Aranda, N. and Mancilla, S. and Arminan, A. and Borgos, S.E. and Hyldbakk, A. and Bogdanska, A. and Gobbo, O.L. and Prina-Mello, A. and Ponti, J. and Calzolai, L. and Zagorodko, O. and Gallon, E. and Nino-Pariente, A. and Paul, A. and Schwartz Jr, S. and Abasolo, I. and Vicent, M.J., In Vivo Antitumor and Antimetastatic Efficacy of a Polyacetal-Based Paclitaxel Conjugate for Prostate Cancer Therapy, Advanced Healthcare Materials, 11, (7), 2022 Journal Article, 2022 DOI

Stavropoulou A.P., Theodosiou M., Sakellis E., Boukos N., Papanastasiou G., Wang C., Tavares A., Corral C.A., Gournis D., Chalmpes N., Gobbo O.L., Efthimiadou E.K., Bimetallic gold-platinum nanoparticles as a drug delivery system coated with a new drug to target glioblastoma, Colloids and Surfaces B: Biointerfaces, 214, 2022 Journal Article, 2022 DOI

Lynch M.J., Gobbo O.L., Advances in non-animal testing approaches towards accelerated clinical translation of novel nanotheranostic therapeutics for central nervous system disorders, Nanomaterials, 11, (10), 2021 Review, 2021 DOI

Erthal LCS, Gobbo OL, Ruiz-Hernandez E, Biocompatible copolymer formulations to treat glioblastoma multiforme., Acta Biomaterialia, 121, (February 2021), 2021, p89 - 102 Journal Article, 2021 TARA - Full Text

Bogdanska, A. and Gobbo, O.L. and Volkov, Y. and Prina-Mello, A., 3D volume segmentation and reconstruction. Supervised image classification and automated quantification of superparamagnetic iron oxide nanoparticles in histology slides for safety assessment, Nanotoxicology, 15, (9), 2021, p1151-1167 Journal Article, 2021 DOI

GA Oluniran, M Cronin, O Gobbo, S O'mara, W O'Connor, N Colgan, M Gilchrist. Apparent diffusion changes in traumatic brain injury model following controlled cortical impact(ed.), European Society of Radiology, Insights into Imaging, Vienna, 10, 27 Feb-3 Mar 2019, 2019 Proceedings of a Conference, 2019

Gobbo OL, Mc Phillips A, Hamilton T, Hayes J and Davey G, Assessment of Intravenous Immunoglobulin treatment on BBB function following inflammation, ISMRM, 2018, 2018 Poster, 2018

Spirou SV, Costa Lima SA, Bouziotis P, Vranje -Djurić S, Efthimiadou EΚ, Laurenzana A, Barbosa A, Garcia-Alonso I, Jones C, Jankovic D, Gobbo OL., Recommendations for In Vitro and In Vivo Testing of Magnetic Nanoparticle Hyperthermia Combined with Radiation Therapy., Nanomaterials (Basel). , 8(5), 2018, p10.3390/nano8050306 Journal Article, 2018 TARA - Full Text

Oliviero L Gobbo, Aislinn Mc Phillips, Tara Hamilton, Jerrard Hayes, Gavin Davey, Assessment of Intravenous Immunoglobulin treatment on BBB function following inflammation, ISMRM, Paris, 2018, edited by ISMRM , 2018 Meeting Abstract, 2018

Edge, D., Shortt, C.M., Johns, E.J., Gobbo, O.L., Markos, F., Abdulla, M.H., Barry, E.F., Assessment of renal function in the anaesthetised rat following injection of superparamagnetic iron oxide nanoparticles, Canadian Journal of Physiology and Pharmacology, 95, (4), 2017, p443-446 Journal Article, 2017 TARA - Full Text DOI

Bianchi, A., Gobbo, O.L., Dufort, S., Sancey, L., Lux, F., Tillement, O., Coll, J.-L., Crémillieux, Y., Orotracheal manganese-enhanced MRI (MEMRI): An effective approach for lung tumor detection, NMR in Biomedicine, 2017 Journal Article, 2017 DOI

Tewes, F, Gobbo, OL, Ehrhardt, C, Healy, AM, Amorphous calcium carbonate based-microparticles for peptide pulmonary delivery, ACS Applied materials and interfaces, 8, (2), 2016, p1164-1175 Journal Article, 2016 TARA - Full Text DOI

Edge D, Shortt CM, Gobbo OL, Teughels S, Prina-Mello A, Volkov Y, MacEneaney P, Radomski MW, Markos F, Pharmacokinetics and bio-distribution of novel super paramagnetic iron oxide nanoparticles (SPIONs) in the anaesthetized pig., Clinical and experimental pharmacology & physiology, 43, (3), 2016, p319-326 Journal Article, 2016 DOI

Kelly JA, Boyle NT, Cole N, Slator GR, Colivicchi MA, Stefanini C, Gobbo OL, Scalabrino GA, Ryan SM, Elamin M, Walsh C, Vajda A, Goggin MM, Campbell M, Mash DC, O'Mara SM, Brayden DJ, Callanan JJ, Tipton KF, Della Corte L, Hunter J, O'Boyle KM, Williams CH, Hardiman O, First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models., Neuropharmacology, 89C, 2015, p193-203 Journal Article, 2015 TARA - Full Text DOI

Gobbo OL, Sjaastad K, Radomski MW, Volkov Y, Prina-Mello A, Magnetic Nanoparticles in Cancer Theranostics., Theranostics, 5, (11), 2015, p1249-63 Review, 2015 DOI URL TARA - Full Text

Gobbo, O.L., Wetterling, F., Vaes, P., Teughels, S., Markos, F., Edge, D., Shortt, C. M., Crosbie-Staunton, K., Radomski, M.W., Volkov, Y., Prina-Mello, A, Biodistribution and pharmacokinetic studies of SPION using particle Electron Paramagnetic Resonance, MRI and ICP-MS, Nanomedicine (Lond.), 10, 2015, p1751 - 1760 Journal Article, 2015 URL DOI

Amaro MI, Tewes F, Gobbo O, Tajber L, Corrigan OI, Ehrhardt C, Healy AM, Formulation, stability and pharmacokinetics of sugar-based salmon calcitonin-loaded nanoporous/nanoparticulate microparticles (NPMPs) for inhalation, International Journal of Pharmaceutics, 483, (1-2), 2015, p6-18 Journal Article, 2015 DOI TARA - Full Text

Oliviero L Gobbo, Andrew J Fagan, Colin Ryan, Deirdre Edge, Christine Shortt, Marek Radomski, Adriele Prina-Mello, Farouk Markos, Yuri Volkov, Quantification of Iron Oxide Nanoparticles in a large animal model using MRI, Proc. Intl. Soc. Mag. Reson. Med, ISMRM, Milan, 2014, 22, 2014, pp2214- Conference Paper, 2014

Mansergh FC, Chadderton N, Kenna PF, Gobbo OL, Farrar GJ, Cell therapy using retinal progenitor cells shows therapeutic effect in a chemically-induced rotenone mouse model of Leber hereditary optic neuropathy, European Journal of Human Genetics, 22, (11), 2014, p1314-20 Journal Article, 2014 DOI TARA - Full Text DOI

Gobbo OL, Fagan J, Ryan C, Edge D, Shortt C, Markos F, Radomski MW, Prina-Mello A and Y Volkov, Quantification of Iron Oxide Nanoparticles in a large animal model using MRI, ISMRM, 2014 Poster, 2014

Shortt, Christine, Edge, Deirdre, Teughels, Stephanie, Roskin, Eric, Verbiest, Joeri, Gobbo, Oliviero, Prina"Mello, Adriele, Volkov, Yuri, Markos, Farouk, Bio"distribution of superparagmetic iron oxide nanoparticles (SPION"s) in the pig (LB578), The FASEB Journal, 28, (S1), 2014 Journal Article, 2014 DOI

Bianchi A, Gobbo OL, Dufort S, Sancey L, Lux F, Tillement O, Coll JL and Crémillieux Y, Intratracheal manganese-enhanced MRI (MEMRI) at very low dose: An effective approach for lung tumor detection, ISMRM, 2014 Poster, 2014

Wetterling F, Fox EK, Brougham DF and Gobbo OL (, Earth-field magnetic resonance imaging- investigating magnetic nanoparticle contrast in ex-vivo liver, ISMRM, 2014 Poster, 2014

Swaminathan J, Gobbo OL, Tewes F, Healy AM, Ehrhardt C, Encapsulation into PEG-liposomes does not improve the bioavailability of pulmonary delivered salmon calcitonin, Journal of Aerosol Medicine and Pulmonary Drug Delivery, 27, (1), 2014, p1-11 Journal Article, 2014 DOI

Rouine, J, Gobbo, OL, Campbell, M, Gigliucci, V, Ogden, I, Smith, KM, Duffy, P, Behan, B, Byrne, D, Kelly, ME, Blau, CW, Kerskens, CM, Harkin, A, MDMA "ecstasy' increases cerebral cortical perfusion determined by bolus-tracking arterial spin labelling (btASL) MRI, BRITISH JOURNAL OF PHARMACOLOGY, 169, (5), 2013, p974-987 Journal Article, 2013 TARA - Full Text DOI

N Chadderton, A Palfi, S Millington-Ward, O Gobbo, N Overlack, M Carrigan, M O'Reilly, M Campbell, C Ehrhardt, U Wolfrum, P Humphries, PF Kenna, GJ Farrar, Intravitreal delivery of AAV-NDI1 provides functional benefit in a murine model of Leber hereditary optic neuropathy, Eur J Hum Genet, 21, (1), 2013, p62-68 Journal Article, 2013 DOI

Gobbo OL, Wetterling F, Crosbie-Staunton K, Vaes P, Teughels S, Markos F, Radomski MW, Prina-Mello A and Volkov Y, Pharmacokinetics and biodistribution of superparamagnetic nanoparticles using pEPR in the mouse: an in vivo, in vitro and ex vivo validation, ISMRM, 2013 Poster, 2013

MM Gaspar, A Radomska, OL Gobbo, MW Radomski, C Ehrhardt, Targeted delivery of transferrin-conjugated liposomes to an orthotopic model of lung cancer in nude rats, J Aerosol Med Pulm Drug Deliv, 25, (6), 2012, p310-318 Journal Article, 2012 DOI

Hanrahan F, Campbell M, Nguyen AT, Suzuki M, Kiang AS, Tam LC, Gobbo OL, Dhubhghaill SN, Humphries MM, Kenna PF, Humphries P, On further development of barrier modulation as a technique for systemic ocular drug delivery., Advances in experimental medicine and biology, 723, 2012, p155-9 Journal Article, 2012

OL Gobbo, M Zurek, F Tewes, C Ehrhardt, Y Crémillieux, Manganese: a new contrast agent for lung imaging?, Contrast Media Mol I, 7, (6), 2012, p542-546 Journal Article, 2012 DOI TARA - Full Text

Gobbo, O.L., Petit, F., Gurden, H., Dhenain, M., In vivo detection of excitotoxicity by manganese- enhanced MRI: Comparison with physiological stimulation, Magnetic Resonance in Medicine, 68, (1), 2012, p234-240 Journal Article, 2012 DOI

Campbell M, Hanrahan F, Gobbo OL, Kelly ME, Kiang AS, Humphries MM, Nguyen AT, Ozaki E, Keaney J, Blau CW, Kerskens CM, Cahalan SD, Callanan JJ, Wallace E, Grant GA, Doherty CP, Humphries P, Targeted suppression of claudin-5 decreases cerebral oedema and improves cognitive outcome following traumatic brain injury., Nature communications, 3, 2012, p849 Journal Article, 2012 DOI

Baginski L, Gobbo OL, Tewes F, Salomon JJ, Healy AM, Bakowsky U, Ehrhardt C, In vitro and in vivo characterisation of PEG-lipid based micellar complexes of salmon calcitonin for pulmonary delivery, Pharm Res, 29, (6), 2012, p1425-1434 Journal Article, 2012 DOI

Gobbo OL, Zurek M, Tewes F, Ehrhardt C and Crémillieux Y., Manganese: a new contrast agent for lung imaging?, International Society of Magnetic Resonance in Medicine (ISMRM), 2011 Poster, 2011

Lesburguères, E., Gobbo, O.L., Alaux-Cantin, S., Hambucken, A., Trifilieff, P., Bontempi, B., Early tagging of cortical networks is required for the formation of enduring associative memory, Science, 331, (6019), 2011, p924-928 Journal Article, 2011

Campbell M, Humphries MM, Nguyen ATH, Gobbo OL, Tam LCS, Suzuki M, Hanrahan F, Ozaki E, Farrar G-J, Kiang A-S, Kenna PF, Humphries P. , Systemic low-molecular weight drug delivery to pre-selected neuronal regions, EMBO Molecular Medicine, 3, (4), 2011, p235-245 Journal Article, 2011 TARA - Full Text

Tewes F, Gobbo OL, Amaro MI, Tajber L, Corrigan OI, Ehrhardt C, Healy AM, Evaluation of HPβCD-PEG microparticles for salmon calcitonin administration via pulmonary delivery, Molecular Pharmaceutics, 8, (5), 2011, p1887 - 1898 Journal Article, 2011 DOI

Dunleavy M, Shinoda S, Schindler C, Ewart C, Dolan R, Gobbo OL, Kerskens CM, Henshall DC, Experimental neonatal status epilepticus and the development of temporal lobe epilepsy with unilateral hippocampal sclerosis., The American journal of pathology, 176, (1), 2010, p330-42 Journal Article, 2010 DOI

Michael E Kelly, Christoph W Blau, Karen M Griffin, Oliviero L Gobbo, James FX Jones and Christian M Kerskens, Quantitative functional magnetic resonance imaging of brain activity using bolus-tracking arterial spin labeling , Journal of Cerebral Blood Flow & Metabolism, 2010 Journal Article, 2010 DOI

MM Gaspar, O Gobbo, C Ehrhardt, Generation of liposome aerosols with the Aeroneb Pro and the AeroProbe nebulisers, J Liposome Res, 20, (1), 2010, p55-61 Journal Article, 2010 DOI

Gobbo, Oliviero L., Models of neurodegeneration in the hippocampus., Saarbrucken, Germany, LAP Lambert Academic Publishing, 2010 Book, 2010

Colgan NC, Cronin MM, Gobbo OL, O'Mara SM, O'Connor WT, Gilchrist MD. , Quantitative MRI analysis of brain volume changes due to controlled cortical impact. , Journal of Neurotrauma, 27, (7), 2010, p1265-1274 Journal Article, 2010 TARA - Full Text

Friedrich Wetterling, Oliviero Gobbo, Martin Tabbert, Sven Junge, Andrew J Fagan Sodium MRI Using a Two-Element Phased Array Coil: A Quantification Accuracy Study(ed.), ISMRM, Proc. Intl. Soc. Mag. Reson. Med, Honolulu, 17, (3281), 2009, 2009 Proceedings of a Conference, 2009

O. Gobbo, M. Campbell, A.Kiang, P. Kenna, C. Kerskens, G. J. Farrar, P. Humphries, RNAi-MEDIATED REVERSIBLE OPENING OF THE BLOOD-BRAIN AND BLOODRETINA BARRIER, MRI Satellite Symposium, 2009 Meeting Abstract, 2009

M. E. Kelly, C. W. Blau, O. L. Gobbo, K. M. Griffin, J. F. Jones, and C. M. Kerskens, Functional bolus-tracking arterial spin labeling; a new approach to quantitative fMRI , International Society for Magnetic Resonance in Medicine, 17th scientific meeting and exhibition, 2009 Conference Paper, 2009

Blau C.W, Griffin K. M., Gobbo O. L., Jones J. F., and Kerskens C. M, Fast bolus-tracking fMRI in medetomidine-sedated rats using intravascular tracer: towards quantitative fMRI, International Society Magnetic Resonance in Medecine, 2009 Poster, 2009

Matthew Campbell, Anh T. H. Nguyen, Anna-Sophia Kiang, Lawrence C. S. Tam, Oliviero L. Gobbo, Christian Kerskens, Sorcha Ni Dhubhghaill, Marian M. Humphries, G.-Jane Farrar, Paul F. Kenna and Peter Humphries, An experimental platform for systemic drug delivery to the retina, Proceedings of the National Academy of Sciences of the United States, 106, (42), 2009, p17817 - 17822 Journal Article, 2009 DOI TARA - Full Text

Kelly M. E.,Blau C.W, Gobbo O. L., Griffin K. M., Jones J. F., and Kerskens C. M., Functional bolus-tracking arterial spin labeling; a new approach to quantitative fMRI., International Society Magnetic Resonance in Medecine, 2009 Oral Presentation, 2009

M.E. Kelly, C.W. Blau, O.L. Gobbo, K.M. Griffin, J.FX. Jones, C.M. Kerskens, QUANTITATIVE FUNCTIONAL MAGNETIC RESONANCE IMAGING WITH BOLUSTRACKING ARTERIAL SPIN LABELLING, MRI Satellite Symposium, 2009 Meeting Abstract, 2009

Gobbo O.L., Gurden H and Dhenain M., Excitotoxic event and physiological stimulation provide similar signal enhancement on manganese-enhanced MRI., International Society Magnetic Resonance in Medecine, 2008 Oral Presentation, 2008

Wetterling, Friedrich; Gobbo, Oliviero; Tabbert, Martin; Junge, Sven; Fagan, Andrew, A Variable Inductively Coupled Two-Element Phased Array Coil for Rat Brain Na-MRI at 7T., MAGMA Magnetic Resonance Materials in Physics Biology and Medicine., 21.30, 2008 Journal Article, 2008

Wetterling F., Gobbo O.L., Tabbert M., Junge S., Fagan A.J., A variable inductively coupled two-element phased array coil for rat brain Na-MRI at 7T., European Society for Magnetic Resonance in Medecine and Biology, 2008 Oral Presentation, 2008

Larkin AE, Fahey B, Gobbo O, Callaghan CK, Cahill E, O'Mara SM, Kelly ÁM., Blockade of NMDA receptors pre-training, but not post-training, impairs object displacement learning in the rat, Brain Research, 1199, 2008, p126 - 132 Journal Article, 2008 URL DOI

F. Wetterling, O. Gobbo, M. Tabbert, S. Junge, A.J. Fagan., Sodium MRI using a two-element phased array coil: A quantification accuracy study, Annual Scientific Meeting, ESMRMB, Valencia, Spain, 2-4th Oct, 2008 Poster, 2008

Gobbo, O.L. & O'Mara, S.M., Combining exercise and cyclooxygenase-2 inhibition does not ameliorate learning deficits after brain insult, despite an increase in BDNF levels, Brain Research, 1046, 2005, p224 - 229 Journal Article, 2005 DOI

Gobbo OL, O'Mara SM., Exercise, but not environmental enrichment, improves learning after kainic acid-induced hippocampal neurodegeneration in association with an increase in brain-derived neurotrophic factor., Behav Brain Res, 159, (1), 2005, p21 - 26 Journal Article, 2005 DOI

Gobbo OL, O'Mara SM, Post-treatment, but not pre-treatment, with the selective cyclooxygenase-2 inhibitor celecoxib markedly enhances functional recovery from kainic acid-induced neurodegeneration, NEUROSCIENCE, 125 , (2), 2004, p317 - 327 Journal Article, 2004 DOI

Gobbo OL, O'Mara SM, Impact of enriched-environment housing on brain-derived neurotrophic factor and on cognitive performance after a transient global ischemia, BEHAVIOURAL BRAIN RESEARCH, 152, 2, (JUL 9), 2004, p231 - 241 Journal Article, 2004 DOI

O Piot-Grosjean, F Wahl, OGobbo, J Stutzmann, Assessment of sensorimotor and cognitive deficits induced by a moderate traumatic injury in the right parietal cortex of the rat., Neurobiology of disease, 8, (6), 2001, p1082 - 1093 Journal Article, 2001

Non-Peer-Reviewed Publications

Almudena Moreno-Borrallo, Friedrich Wetterling, Binh T. Mai, Eduardo Ruiz-Hernandez and Oliviero Gobbo, Preclinical evaluation of a pH-responsive nanocomposite in a refined GL261 Glioblastoma resection model, INOS meeting 2026, 2026 Oral Presentation, 2026

Abeer Alanazi, Maria Santos-Martinez, Carlos Medina, Oliviero Gobbo, Magneto-Mechanical Stress Enhances Nanoparticle-Induced Cytotoxicity in Adipocytes, All-Ireland Schools of Pharmacy Conference, 2026 Poster, 2026

Almudena Moreno-Borrallo, Binh T. Mai, Eduardo Ruiz-Hernandez, Friedrich Wetterling, Oliviero Gobbo, Preclinical evaluation of a pH-responsive nanocomposite in a refined GL261 Glioblastoma resection model, European Association of Neuro-Oncology (EANO) 2026, 2026 Poster, 2026

Ritajaa Manna, Friedrich Wetterling, Maria Jose Santos-Martinez, and Oliviero L. Gobbo, A NEW MAGNETO-MECHANICAL APPARATUS FOR THE TREATMENT OF GLIOBLASTOMA, INOS meeting 2026, 2026 Poster, 2026

Almudena Moreno-Borrallo, Binh T. Mai, Eduardo Ruiz-Hernandez and Oliviero Gobbo, Stimuli-responsive biomaterials for Glioblastoma treatment, All Ireland Schools of Pharmacy Conference, 2025 Poster, 2025

Emke Bootsma, Almudena Moreno-Borrello, Eduardo Ruiz-HernandezOliviero Gobbo, Immunology Matters: Advancing GBM Models in Immunocompetent Mice, INOS meeting 2025, 2025 Poster, 2025

S. Silva Saucedo and O. Gobbo, Magneto-Mechanical Treatment of Glioblastoma Cells Using Iron Oxide Nanoparticles, INOS meeting 2025, 2025 Poster, 2025

Abeer Alanazi, Maria Santos-Martinez, Carlos Medina , Oliviero Gobbo, The Use of Magnetic Nanoparticles and Mechanical Stress to Treat Obesity, British Pharmacological Society Annual Conference, 2025 Poster, 2025

Abeer Alanazi, Maria Santos-Martinez , Carlos Medina , Oliviero Gobbo, The use of magnetic nanoparticles and mechanical stress to treat obesity: effect on macrophages, All Ireland Schools of Pharmacy conference, 2024 Poster, 2024

Anna Bogdanska, Oliviero L. Gobbo, Yuri Volkov and Adriele Prina-Mello, Adapting histology methods to nanoparticle research; from detection to 3D histology volumes, NanoTox2021 virtual conference, 2021 Oral Presentation, 2021

Anna Bogdanska, Oliviero GobboA and Adriele Prina-Mello, 3D histology volumes; an innovative tool for assessment of biodistribution and aggregation of SPIONs in vivo, NanoTech Poland meeting, 2021 Oral Presentation, 2021

Cardoso dos Santos LE, Rakovets, Y, Harkin, A, and Gobbo, OL and Ruiz-Hernandez E , In vivo evaluation of a hydrogel-nanoparticles formulation to treat glioblastoma multiforme, Controlled Research Society , Vitrual Annual Meeting, June 2020, 2020 Poster, 2020

Erthal LCS, Gobbo OL, Ruiz-Hernandez E, Development of injectable hydrogels combined with stimulus-responsive nanocarriers for the treatment of Glioblastoma Multiforme, All Ireland Schools of Pharmacy conference, 2019 Poster, 2019

Erthal LCS, Gobbo OL, Ruiz-Hernandez E, Controlled release of a chemotherapeutic drug from a stimuli responsive nanoparticle incorporated in an injectable hydrogel for the treatment of solid tumours, Controlled Release Society Annual Meeting, 2019 Oral Presentation, 2019

Salerno K, Pescina S, Sala M, Scala MC, Gobbo OL, Santos-Martinez MJ, Padula C, Santi P, Ostacolo C, Nicoli S, Ex vivo study of penetratin-derived decapeptides for trans-corneal delivery, All Ireland Schools of Pharmacy conference, 2019 Poster, 2019

Boumhaouad S, Mamad O, Holmes S, Mawhinney L, Bouhaddou N, Fayne D, Crémillieux Y, Gobbo OL, Detection of lung cancer using MEMRI, 5ème Forum Africain de la Santé, 2019 Poster, 2019

Boumhaouad S, Mamad O, Holmes S, Mawhinney L, Fayne D, Crémillieux Y, Gobbo OL, In vivo detection of metastases using Manganese-Enhanced MRI in an animal model of lung cancer, All Ireland Schools of Pharmacy conference, 2019 Poster, 2019

Villella E, Bogdanska A, Sasse A, Prina-Mello A, Gobbo OL, Superparamagnetic Iron Oxide Nanoparticles for Cancer Hyperthermia Treatment Histological Assessment of Biodistribution and Clearance, All Ireland Schools of Pharmacy conference,, 2019 Poster, 2019

Shortt CM, Edge D, Teughels S, Roskin E, Verbiest J, Gobbo OL, Prina-Mello A, Volkov Y, Markos F (, Bio-distribution of superparamagnetic iron oxide nanoparticles (SPION"s) in the pig" Experimental Biology, FASEB, 2014 Poster, 2014

N Chadderton, A Palfi, S Millington-Ward, O Gobbo, N Overlack, M Carrigan, M O'Reilly, M Campbell, C Ehrhardt, U Wolfrum, P Humphries, PF Kenna, GJ Farrar, Intravitreal delivery of AAV-NDI1 for the treatment of Leber Hereditary Optic Neuropathy, Hum Gene Ther, Retina 2011 - Fighting Blindness, Dublin, Ireland, 11-12/11/2011, 23, (10), 2012, ppA55-A56 Meeting Abstract, 2012

F Tewes, M Zurek, C Ehrhardt, Y Crémillieux, OL Gobbo, Manganese: A new contrast agent for lung imaging?, AAPS J, 25th Annual Meeting of the AAPS, Washington, DC, 23-27/10/2011, 13, (S2), 2011, ppT2069 Meeting Abstract, 2011

Gobbo OL, Tewes F, Swaminathan J, Baginski L, Amaro MI, Umerska A, Tajber L, Corrigan OI, Healy AM and Ehrhardt C, Comparative in vivo evaluation of different delivery systems for the pulmonary administration of salmon calcitonin., Annual Meeting of the AAPS, 2010 Poster, 2010

J Rouine, B Behan, M Kelly, C Blau, O Gobbo, C Kerskens, A Harkin, PERFUSION MAGNETIC RESONANCE IMAGING USING SPIN LABELLING OF ARTERIAL WATER SHOWS INCREASED CORTICAL BLOOD FLOW FOLLOWING METHYLENEDIOXY-METHAMPHETAMINE, 179, 2010, pS108 - S109 Journal Article, 2010

Tewes F, Gobbo OL, Tajber L, Corrigan OI, Ehrhardt C and Healy, sCT loaded HPbCD"PEG particles: Physicochemical properties and sCT pharmacokinetics after pulmonary delivery, Annual Meeting of the AAPS, 2010 Poster, 2010

Gaspar M.M., Radomska A., Gobbo O.L., Radomski M.W., Ehrhardt C., Effect of inhaled anti-cancer liposomes in an orthotopic lung cancer model in the nude rat, 17th Congress of the International Society for Aerosols in Medicine, 2009 Poster, 2009

Gobbo O.L., Gaspar M.M., Radomska A., Radomski M.W., Ehrhardt C., Treatment of an orthotopic lung cancer model in the nude rat with liposome, 23rd Annual Meeting of the AAPS, 2009 Poster, 2009

Gobbo O.L.,Campbell M., Kiang A-S., Kenna P., Kerskens C., Farrar G.J., Humphries M., Humphries P., RNAi-mediated reversible opening of the blood-brain barrier and blood-retina barrier, Annual Neuroscience Ireland Conference, 2009 Oral Presentation, 2009

Cronin M., Callanan S., Worrell S., Gilchrist M.D., Gobbo O. and O"Connor W.T, A Study of The Temporal Sequellae Following Controlled Cortical Impact to Rat Frontal Cortex Using Magnetic Resonance Image Analysis., Annual UCD Conway Festival of Research, UCD, 2008 Poster, 2008

Cronin M., Colgan N.C., Gilchrist M.D., Gobbo O.L., O'Mara S.M., O'Connor W.T., A magnetic resonance image analysis of the temporal sequellae following controlled cortical impact to rat frontal cortex, Annual Society for Neuroscience Meeting, 2008 Poster, 2008

Hennigan A., Larkin A., Gobbo O., Fahej B., O'Mara S. M., Kelly A. M., Spatial learning in the rat is NMDA-receptor dependent: evidence from an object displacement task, Acta Neurobiologiae Experimentalis, 65, (5), 2005, p52- Journal Article, 2005

Fahey B, Cowley TR, Gobbo OL, Mullally S, O"Dwyer AM, and OMara SM, Interferon-alpha-induced deficits in hippocampal-dependent tasks., FENS, A150.10, 2004 Poster, 2004

Brotons JR, Gobbo OL, Sanchez-Vives MV and OMara SM, Subiculum place cells properties in multiple open field environments: environmental manipulations could imply contextual coding., FENS abstracts, A112.8, 2004 Poster, 2004

O"Mara SM, Fahey B, Hickey B, Gobbo OL, Mullally S and O"Dwyer AM, Anxiogenic and depressive-like effects of interferon-alpha treatment., FENS abstracts, A217.7, 2004 Poster, 2004

Cowley TR, Gobbo OL, Brotons J, Fahey B, Pittenger C, Kandel ER and OMara SM, Disruption of Presynaptic CREB impairs LTP induction via a BDNF dependent mechanism, FENS abstract, A015.15, 2004 Poster, 2004

Gobbo OL and OMara SM, Physical exercise provides functional protection from kainic acid-induced neurodegeneration., FENS abstract, A112.27, 2004 Poster, 2004

Gobbo OL and O"Mara SM, Enriched-environment housing enhances performance on odor discrimination, object exploration and spatial learning tasks independently of transient global ischemia., FENS abstracts, A224.14, 2002 Poster, 2002

Mullally SL, Brotons JR, Cowley TR, Gobbo OL, Shaw KN and O"Mara SM, Exercise and antidepressant treatment diminishes the behavioural effects of repeated moderate stress on spatial learning., FENS abstracts, A174.20, 2002 Poster, 2002

O'Mara SM, Anderson M and Gobbo OL, Single-unit Recordings in the subiculum of the freely-moving rat in the open field and radial arm maze., Society For Neuroscience Abstracts, 26, 2000, pp360Meeting Abstract, 2000, 2000 Poster, 2000

Assunta Imperato, Saliha Moussaoui, Carmen Obinu, Oliviero Gobbo, 'NEW THERAPEUTIC APPLICATION OF P SUBSTANCE ANTAGONISTS', Aventis Pharma SA, 1996, 22 November 2024, Aventis Pharma SA Patent, 1996 URL

Research Expertise

Projects

  • Title
    • Zebrafish Research Programme and Facility Development
  • Summary
    • This project will establish a dedicated zebrafish research facility within Trinity College Dublin"s School of Pharmacy and Pharmaceutical Sciences, creating a shared research infrastructure to support interdisciplinary biomedical and pharmaceutical research. The facility will provide researchers with access to a versatile and cost-effective vertebrate model that offers significant advantages for investigating human health and disease. Zebrafish are increasingly important in biomedical research because of their genetic similarity to humans, rapid development, external fertilisation, optical transparency and high genetic tractability. Their transparent embryos allow developmental processes to be observed in real time, providing an exceptional model for studying embryogenesis, organogenesis, tissue regeneration and other fundamental biological processes. Advances in genome-editing technologies further enable precise investigation of gene function and molecular pathways relevant to human disease.
  • Funding Agency
    • Research Boost Programme 2024, TCD- HEA
  • Date From
    • 2025

Keywords

Anticancer Drug Design; CANCER; Cancer drug discovery; Drug Delivery Systems; Drug discovery; Drug discovery, profiling, targeting; Imaging Techniques; In vitro testing, trial methods; Nanomedicine; nanotoxicology; Neuroimaging; Neuropharmacology; PHARMACOLOGY; Pharmacy; pulmonary drug delivery

Recognition

Representations

I co-founded the Irish Neuro-Oncology Society (INOS) in February 2025, creating a platform for clinicians, researchers, trainees, charities and allied healthcare professionals. I currently serve as President, supporting its strategic development and promoting national collaboration across disciplines.

Member of Animal Welfare Body, TCD, since 2025

Member of the Animal Research Ethics Committee (AREC), TCD, 2016-2025

Member of COST Action CA23132, Magnetic Particle Imaging for Next-Generation Theranostics and Medical Research (NexMPI). 2024-2028

Member of the COST action CA22103 · A Comprehensive Network Against Brain Cancer- 2023-2027

Member of the 2D-BioPAD Scientific and Industrial Advisory Board, a project funded by the European Union under Grant Agreement No. 101120706. The project, 2D-BioPAD, Supple Graphene Bio-Platform for Point-of-Care Early Detection and Monitoring of Alzheimer s Disease, focuses on developing innovative graphene-based biosensing technologies for the early detection and monitoring of Alzheimer s disease. 2023-2027

Irish Representative, Management Committee of COST Action CA171404, Cancer Nanomedicine-from the bench to the bedside (NANO2CLINIC). 2018-2022

I have been a member of the Editorial Board of the journal Nanomaterials since 2021, contributing to the peer review and development of research in the field.

Irish Representative, Management Committee of COST Action TD 1402, Multifunctional Nanoparticles for Magnetic Hyperthermia and Indirect Radiation Therapy. Vice-leader of WG5. 2014-2018

Member of the Magnetic Resonance Imaging (MRI) committee, TCD. 2007-2010

Awards and Honours

Trinity Boost Funding Programme 2021

European Cooperation in Science and Technology Actions (COST actions): Short Term Scientific Mission Award dedicated to group leaders 2019

The Dean's Research Initiatives Fund Award (PI), Faculty of Health Sciences, TCD 2017

Innovation Bursary for post-doctoral researchers 2010

Memberships

Irish Neuro Oncology Society 2025

European Technology Platform Nanomedicine 2016

International Society for Magnetic Resonance in Medicine 2006

Federation of European Neuroscience Societies 2000