Biography
Dr Laura McCullagh is Chief I Pharmacist & Head of Research, National Centre for Pharmacoeconomics (NCPE) and Clinical Senior Lecturer, Pharmacology & Therapeutics. She holds a PhD for her research in Health Technology Assessment (HTA). In the NCPE, she has led over 60 HTA evaluations; these have informed HSE drug reimbursement decision-making. Previous roles have included Associate Professor of HTA & Pharmacoeconomcis, Discipline of Pharmacology & Therapeutics, Trinity College Dublin. She represents Ireland on the European Commission HTA Coordination Group (Medicinal Products). She publishes research in international, peer-reviewed journals. She is a member of Cochrane. She is on the Editorial Boards of PharmacoEconomics and Frontiers in Medicine. She provides peer-review for heath-economics and clinical journals, for the Medical Research Council, UK and the Veni Scheme, Netherlands Organization for Scientific Research. She is a member of the ISPOR Europe Conference Research Programme Committee. She is on the Research Ethics Committee, Health Policy and Management-Centre for Global Health, Trinity College Dublin. Dr McCullagh is on the Board of Management and Court of Examiners, MSc Pharmaceutical Medicine, Disp. Pharmacology & Therapeutics. She supervises post-doctoral, PhD, MD, MSc and undergraduate researchers. She is internal examiner to PhD and MSc candidates. She holds undergraduate and postgraduate teaching commitments. She leads the development and implementation of the HTA Module of the Annual National Patient Education Programme (in collaboration with IPPOSI). She is a member of the National Cancer Epi Network. She was a member of the Pan-European Piperska Group (2013-2017). She was a member of the National Prostate Cancer Research Consortium (2014-2015). She was on the Expert Advisory Group for the HTA of a National Screening Programme for Atrial Fibrillation. She was a member of the National Cancer Control Programme Technology Review Committee (2015-2018).
Publications and Further Research Outputs
Peer-Reviewed Publications
Barrett R, Smith A, Gorry C, Doran S, Barry M, McCullagh L, A Managed Access Protocol for Liraglutide for Weight Management: A Retrospective, Observational Study in Ireland, Value in Health, 2025
Sharma, S., Carey, N., McConnell, D. Lowery, M., O'Sulliavan, J., McCullagh, L. for the HEALED Consortium, Systematic Review of Economic Evaluations of Systemic Treatments for Advanced and Metastatic Gastric Cancer, PharmacoEconomics, 2024
Cassidy O, Harte M, Trela-Larsen L, Walsh C, White A, McCullagh L, Leahy J., A comparison of relative-efficacy estimate(s) derived from both Matching-Adjusted Indirect Comparisons and Standard Anchored Indirect Treatment Comparisons., Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2023, pS1098-3015(23)03061-9
Niamh Carey, Joy Leahy, Lea Trela-Larsen, Laura Mc Cullagh, Michael Barry, Cost-utility and value of information analysis of tisagenlecleucel for relapsed/refractory diffuse large B-cell lymphoma in the Irish healthcare setting, Journal of Market Access & Health Policy, 11, (1), 2023
Rosealeen Barrett, Michael Barry, Laura McCullagh, Health technology management: the experience of a managed access approach to the reimbursement of dupilumab in Ireland, Irish Journal of Medical Science (1971 -), 2023
Croke A, Cardwell K, Clyne B, Moriarty F, McCullagh L, Smith SM., The effectiveness and cost of integrating pharmacists within general practice to optimize prescribing and health outcomes in primary care patients with polypharmacy: a systematic review., BMC Prim Care, 24, (1), 2023, p41
Claire Gorry, Laura McCullagh, Helen O'Donnell, Sarah Barrett, Susanne Schmitz, Michael Barry, Kay Curtin, Eamon Beausang, Rupert Barry, Imelda Coyne, Neoadjuvant treatment for stage III and IV cutaneous melanoma, Cochrane Database of Systematic Reviews, 2023, (1), 2023, p1 - 102
O'Callaghan J, Tilson L, Fogarty E, McCullagh L, Clinical expert opinion to inform Health Technology Assessments., Irish Medical Journal, 116, (8), 2023
Carey N, Harte M, Mc Cullagh L., A text-mining tool generated title-abstract screening workload savings: performance evaluation versus single-human screening., Journal of clinical epidemiology, 149, 2022, p53-59
Carey N, Leahy, J, Trela-Larsen L, McCullagh L., & Barry, M, Tisagenlecleucel for relapsed/refractory acute lymphoblastic leukemia in the Irish healthcare setting: Cost-effectiveness and value of information analysis., International Journal of Technology Assessment in Health Care,, 38, (1 e56), 2022, p1 - 11
Castro P.D., Reynolds C.M., Kennelly S., Geraghty A.A., Finnigan K., McCullagh L., Gibney E.R., Perrotta C., Corish C.A., An investigation of community-dwelling older adults' opinions about their nutritional needs and risk of malnutrition; a scoping review, Clinical Nutrition, 2021
Varley Á, Tilson L, Fogarty E, McCullagh L, Barry M., The Utility of a Rapid Review Evaluation Process to a National HTA Agency., PharmacoEconomics, 2021
Croke A, Moriarty F, Boland F, McCullagh L, Cardwell K, Smith SM, Clyne B., Integrating clinical pharmacists within general practice: protocol for a pilot cluster randomised controlled trial., BMJ Open, 11, (3), 2021, pe041541
Castro, P.D., Reynolds, C.M., Kennelly, S., Geraghty, A.A., Finnigan, K., McCullagh, L., Gibney, E.R., Perrotta, C., Corish, C.A., An investigation of community-dwelling older adults' opinions about their nutritional needs and risk of malnutrition; a scoping review, Clinical Nutrition, 2021
Kennedy, Cormac, McCullagh, Laura, Adams, Roisin, Trela-Larsen, Lea, Tilson, Lesley, Barry, Michael, Estimating the Theoretical Cost Implications of Funding New Drugs Considered Not to Be Cost-Effective, Value in Health, 2021
Dominguez Castro, Patricia, Reynolds, Ciara, Bizzaro, Maria Gabriella, Kennelly, Sharon, Clyne, Barbara, Bury, Gerard, Bradley, Catriona, Finnigan, Karen, McCullagh, Laura, Murrin, Celine, Perrotta, Carla, Gibney, Eileen R, Corish, Clare A, Characteristics and determinants of high volume dispensing in long-term oral nutritional supplement users in primary care: a secondary analysis, BJGP Open, 2021, pBJGPO.2020.0131
Castro, Patricia Domínguez, Kennelly, Sharon, Clyne, Barbara, Bury, Gerard, Bradley, Catriona, Finnigan, Karen, McCullagh, Laura, Barry, Michael, Murrin, Celine, Perrotta, Carla, Villaroel, Katherine Loayza, Reynolds, Ciara, Gibney, Eileen, Corish, Clare, A preliminary qualitative study of general practitioners" views on malnutrition management and oral nutritional supplementation prescription in the community, Proceedings of the Nutrition Society, 79, (OCE2), 2020
Dominguez Castro P, Reynolds CM, Kennelly S, Clyne B, Bury G, Hanlon D, Murrin C, McCullagh L, Finnigan K, Clarke S, Browne S, Perrotta C, Gibney ER, Corish CA., General practitioners' views on malnutrition management and oral nutritional supplementation prescription in the community: A qualitative study., Clinical nutrition ESPEN, 36, 2020, p116-127
Abdelaal Ahmed Mahmoud M Alkhatip, A., Conroy, P., Hamza, M.K., Murphy, I., Purcell, A., McGuire, D., The authors reply, Critical Care Medicine, 48, (8), 2020, pE731-E732
Warren, E., Fuller, R., Mulkerrin, L., Varley, A., McCullagh, L., Barry, M., PPM5 Health Technology Assessment and Companion Diagnostics: A Review of Submissions to the Ncpe from 2012-2019, Value in Health, 23, 2020, pS687-S688
Dominguez Castro, P., Reynolds, C., Bizzaro, M.G., Kennelly, S., Clyne, B., Bury, G., Bradley, C., Finnigan, K., McCullagh, L., Barry, M., Murrin, C., Perrotta, C., Gibney, E., Corish, C., The characteristics of long-term oral nutritional supplement users in Ireland, Clinical Nutrition ESPEN, 40, 2020, p496-497
Lamrock F, McCullagh L, Tilson L, Barry M., A retrospective analysis of budget impact models submitted to the National Centre for Pharmacoeconomics in Ireland., The European journal of health economics : HEPAC : health economics in prevention and care, 21, (6), 2020, p895-901
Reynolds, C.M., Dominguez Castro, P., Bardon, L.A., Kennelly, S., Clyne, B., Bury, G., Bradley, C., Finnigan, K., McCullagh, L., Barry, M., Murrin, C., Perrotta, C., Gibney, E., Corish, C., It Takes A Village: Patient Perspectives On The Management Of Malnutrition In The Community, Clinical Nutrition ESPEN, 40, 2020, p464-465
James, O., Cardwell, K., Moriarty, F., M Smith, S., Clyne, B., Barry, M., Boland, F., Clarke, S., Finnigan, K., Daly, M., McCullagh, L., Wallace, E., Kirke, C., Bradley, C., Gallagher, P., Murphy, E., Byrne, A.M.P., Croke, A., Fahey, T., Pharmacists in general practice: A qualitative process evaluation of the General Practice Pharmacist (GPP) study, Family Practice, 37, (5), 2020, p711-718
Gorry C, McCullagh L, Barry M., Transferability of Economic Evaluations of Treatments for Advanced Melanoma., PharmacoEconomics, 38, (2), 2020, p217-231
Gorry C, McCullagh L, Barry M., Economic Evaluation of Systemic Treatments for Advanced Melanoma: A Systematic Review., Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 23, (1), 2020, p52-60
Castro, Patricia Domínguez, Kennelly, Sharon, Murrin, Celine, Bradley, Catriona, Clyne, Barbara, Bury, Gerard, Finnigan, Karen, McCullagh, Laura, Barry, Michael, Browne, Sarah, Reynolds, Ciara, Bardon, Laura, Gibney, Eileen, Corish, Clare, A preliminary qualitative study of nurses" and dietitians" views on malnutrition management and oral nutritional supplementation prescription in the community, Proceedings of the Nutrition Society, 79, (OCE2), 2020
Castro, P. Dominguez, Reynolds, C., Kennelly, S., Clyne, B., Bury, G., Bradley, C., Finnigan, K., McCullagh, L., Barry, M., Murrin, C., Perrotta, C., Gibney, E., Corish, C., "Don"t Go Near The Word Malnutrition"; A qualitative study of community healthcare professionals and patients views on the term malnutrition, Clinical Nutrition ESPEN, 40, 2020, p592
Leahy J, Hickey C, McConnell D, Cassidy O, Trela-Larsen L, Barry M, Tilson L, McCullagh L, NCPE Review Group., Coronavirus Disease 2019: Considerations for Health Technology Assessment From the National Centre for Pharmacoeconomics Review Group., Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 23, (11), 2020, p1423-1426
Kennedy, C., McCullagh, L., Adams, R., Trela-Larsen, L., Tilson, L., Barry, M., PMU65 Drugs with Incremental Cost Effectiveness Ratios ABOVE the Irish Threshold and Subsequent Price Negotiations, Value in Health, 23, 2020, pS613
Kennedy, C., McCullagh, L., Adams, R., Trela-Larsen, L., Tilson, L., Barry, M., PMU52 The Reliability of Budget IMPACT Predictions for Drugs with Incremental Cost Effectiveness Ratios ABOVE the Irish Threshold, Value in Health, 23, 2020, pS612
O'Donnell H, McCullagh L, Barry M, Walsh C., The Interaction between Price Negotiations and Heterogeneity: Implications for Economic Evaluations., Medical decision making : an international journal of the Society for Medical Decision Making, 40, (2), 2020, p144-155
Dominguez Castro, P., Reynolds, C., Bizzaro, G., Kennelly, S., Clyne, B., Bury, G., Bradley, C., Finnigan, K., McCullagh, L., Barry, M., Murrin, C., Perrotta, C., Gibney, E., Corish, C., Large number of prescribed central nervous system drugs and younger age predict the use of more oral nutritional supplements units, Clinical Nutrition ESPEN, 40, 2020, p496
Reynolds, C.M., Dominguez Castro, P., Kennelly, S., Clyne, B., Bury, G., Bradley, C., Finnigan, K., McCullagh, L., Barry, M., Murrin, C., Perrotta, C., Gibney, E., Healthcare professionals" preferences for the delivery, content and structure of a malnutrition education programme: An exploratory qualitative Study, Clinical Nutrition ESPEN, 40, 2020, p465
Usher C, McCullagh L, Tilson L, Barry M., Analysis of Health Technology Assessments of Orphan Drugs in Ireland from 2012 to 2017., Pharmacoecon Open, 3, (4), 2019, p583-589
Lee, A., Tan, S., Usher, C., Barry, M., McCullagh, L., PNS181 SUBMISSIONS TO A NATIONAL HTA AGENCY IN IRELAND: DRUGS WITH DESIGNATED ORPHAN STATUS, Value in Health, 22, 2019, pS792
Carey N, McCullagh L, Barry M , Evaluating The Quality And Risk Of Bias In Overall Survival Outcomes From Non-Randomised Car T-Cell Therapy Pivotal Trials , ISPOR Europe , Copenhagen, Denmark, November 2019, 2019
Carey, N., McCullagh, L., Barry, M., PCN6 EVALUATING THE QUALITY AND RISK OF BIAS IN OVERALL SURVIVAL OUTCOMES FROM NON-RANDOMISED CAR T-CELL THERAPY PIVOTAL TRIALS, Value in Health, 22, 2019, pS436
Maguire, Orla, McCullagh, Laura, Usher, Cara, Barry, Michael, OP65 Pharmacoeconomic Evaluation Of Orphan Drugs: Impact Of Extra Criteria?, International Journal of Technology Assessment in Health Care, 35, (S1), 2019, p16-16
Carey, Niamh, Harte, Marie, Gorry, Claire, McCullagh, Laura, OP136 Provision Of A Chimeric Antigen Receptor T-Cell Program: A Rapid Review, International Journal of Technology Assessment in Health Care, 35, (S1), 2019, p31-31
Trela-Larsen, L., Usher, C., McCullagh, L., Barry, M., Walsh, C., PCN498 REAL-WORLD EVIDENCE ON THE UTILISATION OF ABIRATERONE AND ENZALUTAMIDE IN IRELAND, Value in Health, 22, 2019, pS534
Gorry, Claire and Leahy, Joy and Lamrock, Felicity and Walsh, Cathal and White, Arthur and Barry, Michael and McCullagh, Laura, VP82 Impact of Evidence Synthesis Methods on Outcome of Economic Evaluation, International Journal of Technology Assessment in Health Care, 35, (S1), 2019, p93 - 94
Karen Cardwell, Susan M Smith, Barbara Clyne, Laura McCullagh, Emma Wallace, Ciara Kirke, Tom Fahey, Frank Moriarty, Evaluation of the General Practice Pharmacist (GPP) intervention to optimise prescribing in Irish primary care: a non-randomised pilot study, 2019
Gorry C, McCullagh L, Barry M, Potential Budget Impact Of Adjuvant Treatments For Stage Iii Melanoma In Ireland , ISPOR Europe, Copenhagen, Denmark, 2019, 2019
Gorry, C., Leahy, J., Lamrock, F., Barry, M., McCullagh, L., PCN184 ECONOMIC EVALUATION OF CHECKPOINT INHIBITORS FOR THE TREATMENT OF ADVANCED MELANOMA IN THE IRISH HEALTHCARE SETTING, Value in Health, 22, 2019, pS471-S472
McCabe, L., Moloney, D., Barry, M., Usher, C., McCullagh, L., PCN272 - ANALYSIS OF PHARMACY CLAIMS FOR HIGH COST DRUGS: LENALIDOMIDE UTILISATION AND EXPENDITURE IN IRELAND, Value in Health, 21, 2018, pS60
Carey, N, McCullagh, L, Barry, M, Tilson, L, PRM272 - THE EUNETHTA TRANSFERABILITY TOOL: APPLICATION TO NOVEL TREATMENTS FOR RELAPSED REFRACTORY MULTIPLE MYELOMA IN THE IRISH HEALTHCARE SETTING, Value in Health, 21, 2018, pS402-S403
Cardwell K, Clyne B, Moriarty F, Wallace E, Fahey T, Boland F, McCullagh L, Clarke S, Finnigan K, Daly M , Barry M, Smith, S , Supporting prescribing in Irish primary care: Protocol for a non-randomised pilot study of a general practice pharmacist (GPP) intervention to optimise prescribing in primary care., Pilot and Feasibility Studies, 4, (122), 2018
Gorry C, McCullagh L, O'Donnell H, Barrett S, Schmitz S, Barry M, Curtin K, Beausang E, Barry R, Coyne I. , Neoadjuvant Treatment for malignant and metastatic melanoma. , Cochrane Database of Systematic Reviews. , (3), 2018
O'Donnell H, McCullagh L, Barry, M, Walsh. C. , Negotiating The Relationship Between Price and Volume: Implications for ICER Calculations in Heterogeneous Treatment Populations., 40th Annual Meeting of the Society for Medical Decision Making, Montréal, Québec, Canada, October 13-17, 2018, 2018
McCullagh L, Schmitz S, Barry M, Walsh C, Examining the Feasibility and Utility of Estimating Partial Expected Value of Perfect Information (via a Nonparametric Approach) as Part of the Reimbursement Decision-Making Process in Ireland: Application to Drugs for Cancer, PharmacoEconomics, 2017
Hickey, N, Corcoran, A, Usher, C, Barry, M, McCullagh, L, Analysis Of Pharmacy Claims For High Cost Drugs: Ruxolitinib Utilisation And Expenditure In Ireland, Value in Health, 20, (9), 2017, pA462
Moorkens E, Vulto AG, Huys I, Dylst P, Godman, B, Keuerleber, S Claus B, Dimitrova M McCullagh L et al, Policies for biosimilar uptake in Europe: An overview, ONE, 2017
Corcoran A, Hickey N, Barry M, Usher C, McCullagh L, Ivacaftor for cystic fibrosis; An evaluation of real world utilisation and expenditure in the Irish Healthcare Setting., Irish Medical Journal, 110, (8), 2017
Evelien Moorkens , Arnold G. Vulto, Isabelle Huys,.....Laura mccullagh et al, Policies for biosimilar uptake in Europe: An overview, PLOS ONE, 2017
Gorry, C, Barry, M, McCullagh, L, Analysis Of Hospital Episode Statistics To Identify Hopsital Resource Use Due To Skin Cancer In Ireland, Value in Health, 20, (9), 2017, pA506
McCullagh, L, Partial EVPI feasible as part of HTA in Ireland, PharmacoEconomics & Outcomes News, 785, (1), 2017, p25-25
Schmitz S, McCullagh L, Adams R, Walsh C, Identifying and Revealing the Importance of Decision-Making Criteria for Health Technology Assessment: A Retrospective Analysis of Reimbursement Recommendations in Ireland, PharmacoEconomics, 2016
Schmitz S, McCullagh L, Dolan E, Walsh C, The Quev Score: A Quantitative Evaluation of the Quality of Clinical Evidence in HTA, Value Health, 19, (7), 2016, ppA499 - A499
Gorry C, McCullagh M, Barry M, Drug Utilisation of Braf Inhibitors for Melanoma in Ireland, Value Health, 19, (7), 2016, ppA728 - A728
Dolan E, Schmitz S, Barry M, McCullagh L, Movement of Drugs for Cancer Through The Pharmacoeconomic Evaluation Process in Ireland: Consideration Given to The Quality of Clinical Evidence, Value Health, 2016, 19, (7), 2016, ppA757 - A757
Morgan RB, McCullagh L, Barry M, Daly C, The cost of inpatient management of heart failure patients: a microcosting study in the Irish healthcare setting., 2016
McCullagh L, Barry M, The Pharmacoeconomic Evaluation Process in Ireland, PharmacoEconomics, 34, (12), 2016, p1267 - 1276
Ermisch M, Bucsics A, Vella Bonanno P, Arickx F, Bybau A, Bochenek T, van de Casteele M, Diogene E, Fürst J, Garuolien" K, van der Graaff M, Gulbinovi" J, Haycox A, Jones J, Joppi R, Laius O, Langner I, Martin AP, Markovic-Pekovic V, McCullagh L, Payers' Views of the Changes Arising through the Possible Adoption of Adaptive Pathways., 2016
O'Donnell H, McCullagh L, Barry M, The Potential Budget Impact of PCSK9 Inhibitors in Ireland, Value Health, 2016, 7, (19), 2016, ppA643 - A643
Spillane S, McCullagh L, Barry M, Usher C, Analysis of Pharmacy Claims for High Cost Oncology Products: Abiraterone and Enzalutamide Usage in Mcrpc in Ireland, Value Health, 19, (7), 2016, ppA754 - A754
Godman B, Malmström RE, Diogene E, Gray A, Jayathissa S, Timoney A, Acurcio F, Alkan A, Brzezinska A, Bucsics A, Campbell SM, Czeczot J, de Bruyn W, Eriksson I, Yusof FA, Finlayson AE, Fürst J, Garuoliene K, Guerra Júnior A, Gulbinovi, J, Are new models needed to optimize the utilization of new medicines to sustain healthcare systems?, 2015
McCullagh L, Adams R, Barry M, Schmitz S, Walsh C, Evaluation Of 'Real-World' Ipilimumab Data In Ireland., Value Health, 18, (7), 2015, ppA441-A441-
McCullagh LM, Tilson L, Adams R, Barry M, HTA Informed Price Negotiations: Cost Savings To The Health Payer in Ireland., 2014
O'Brien C, Fogarty E, Walsh C, Dempsey O, Barry M, Kennedy MJ, McCullagh L, The cost of the inpatient management of febrile neutropenia in cancer patients - a micro-costing study in the Irish healthcare setting. , European Journal of Cancer Care, 2014
McCullagh L, Barry M., Survival analysis used in company submissions to the National Centre for Pharmacoeconomics, Value Health, 16, (7), 2013, ppA398 - A398
Adams R, Gray E, McCullagh L, Schmitz S, Barry M, Walsh C, Budget impact and thresholds: how are real decisions made? Expected utility or Prospect Theory, Value Health, 16, (7), 2013, ppA490 - A490
Godman B, Finlayson AE, Cheema PK, Zebedin-Brandl E, Gutiérrez-Ibarluzea I, Jones J, Malmström RE, Asola E, Baumgärtel C, Bennie M, Bishop I, Bucsics A, Campbell S, Diogene E, Ferrario A, Fürst J, Garuoliene K, Gomes M, Harris K, Haycox A, Personalizing health care: feasibility and future implications., 2013
Malmström RE, Godman BB, Diogene E, Baumgärtel C, Bennie M, Bishop I, Brzezinska A, Bucsics A, Campbell S, Ferrario A, Finlayson AE, Fürst J, Garuoliene K, Gomes M, Gutiérrez-Ibarluzea I, Haycox A, Hviding K, Herholz H, Hoffmann M, Jan S, Dabigatran - a case history demonstrating the need for comprehensive approaches to optimize the use of new drugs., 2013
Schmitz S, McCullagh L, Adams R, Barry M, Walsh C, A retrospective analysis of drug reimbursement decisions in Ireland. A multi criteria decision analysis approach., Value Health, 2013, 16, (7), 2013, ppA465 - A465
McCullagh L, Walsh C, Barry M , Value-of-Information Analysis to Reduce Decision Uncertainty Associated with the Choice of Thromboprophylaxis after Total Hip Replacement in the Irish Healthcare Setting., PharmacoEconomics, 30, (10), 2012, p941 - 959
McCullagh L, Barry M, Prescribing trends for dabigatran etexilate in primary care., 2012
McCullagh L, Walsh C, Barry M, Integration of value of information into the decision making process in Ireland, Value Health, 15, (7), 2012, ppA317 - A317
McCullagh L, Usher C, Barry M, A review of the primary care prescribing of dabigatran etexilate and rivaroxaban in Ireland, Value Health, 14, (7), 2011, ppA390 - A390
McCullagh L, Walsh C, Barry M, Prioritizing further research using the expected value of perfect information: application to VTE prophylaxis post total hip replacement, Value Health, 13, (7), 2010, ppA359 - A359
McCullagh L, Tilson L, Walsh C, Barry M, Cost effectiveness of rivaroxaban and dabigatran etexilate for the prophylaxis of venous thromboembolism and associated long term compliactions post total hip replacement in Ireland, Value Health, 12, (7), 2009, ppA334 - A334
McCullagh L, Tilson L, Walsh C, Barry M, A cost-effectiveness model comparing rivaroxaban and dabigatran etexilate with enoxaparin sodium as thromboprophylaxis after total hip and total knee replacement in the irish healthcare setting., 2009
Hopkins S, Lambourne J, Farrell G, McCullagh L, Hennessy M, Clarke S, Mulcahy F, Bergin C., Role of individualization of hepatitis C virus (HCV) therapy duration in HIV/HCV-coinfected individuals., HIV Med. , 7, (4), 2006, p248-54.
Clarke S, Delamere S, McCullagh L, Hoskins S, Bergin C, Mulcahy F, Assessing limiting factors to the acceptance of antiretroviral therapy in a large cohort of injecting drug users, HIV Med, 4, (1), 2003, p33 - 37
Non-Peer-Reviewed Publications
Kearns, P; McCullagh L; Norris L; McConnell D, Evaluating The Cost-Effectiveness of Repeated Serological Biomarker Screening Compared to the Khorana Risk Score for Guiding Thromboprophylaxis Prescription in Patients Receiving Chemotherapy, SPHeRE Network 11th Annual Conference: Translating Research to Health Policy and System Change, Royal College of Surgeons Ireland, Dublin, 04 March 2025, 2025
Research Expertise
Description
Dr McCullagh is Chief I Pharmacist, Head of Research, NCPE and Clinical Senior Lecturer, Trinity College Dublin. She has been the lead on over 60 HTA evaluations of drugs for which reimbursement by the HSE is sought. Each report details comparative-effectiveness, cost-effectiveness and the expected budget impacts of the drug under consideration. The reports inform the HSE reimbursement decision-making process. Dr McCullagh publishes research undertaken in HTA, including in: comparative clinical-effectiveness and cost-effectiveness of drugs, evidence synthesis (for comparative-efficacy), value-of-information analysis, multiple-criteria-decision analysis, survival analysis (of immature clinical-trial data), cost of health-care, cost-containment initiatives and analysis of drug utilization and prescribing & expenditure trends. Dr McCullagh is a primary investigator and a co-applicant on various research grants. She is a member of the HEALED consortium funded under the Disruptive Technologies Innovation Fund, Department of Enterprise and Innovation, Ireland. Here she is leading the HTA of novel immunotherapies for the treatment of cancers. She was a co-applicant on a Health Research Board (HRB) Applied-Partnership Award which examined how drug utilization and outcomes analyses can inform HTA and reimbursement. A HRB RCQPS Award investigated how a GP practice-based Pharmacist Medicines Optimization Programme supports prescribing in primary care. A HRB RCQOS Award investigated how a multi-disciplinary prescribing strategy supports prescribing of oral nutritional supplements by GPs. Previously, she was a HRB Interdisciplinary Capacity Enhancement research fellow at Trinity College Dublin. This research programme investigated novel approaches to cancer prevention, treatment and cost in conjunction with the National Cancer Registry of Ireland and the NCPE. Dr McCullagh publishes research in top-in-field, European and International peer-reviewed journals and conferences. She is on the Editorial Boards of PharmacoEconomics and Frontiers in Medicine. She provides peer-review for heath-economics and clinical journals, for the Medical Research Council, UK and the Veni Scheme, Netherlands Organization for Scientific Research. She is on the ISPOR European Conference Research Programme Committee. Dr McCullagh supervises Post-doctoral, PhD, MD, MSc and undergraduate research candidates. She is a member of the Health Policy and Management-Centre for Global Health REC, Trinity College Dublin.Recognition
Representations
Ireland Representative (medicinal products), Health Technology Assessment Coordination Group (HTACG), European Commission.
Lead HTA Assessor, Senior Management, Head of Research, NCPE
Lead, Development & Implementation of HTA Module, National Annual Patient Education Programme in Health Innovation, EUPATI for Irish Patient Communities (in association with IPPOSI)
Editorial Board, Frontiers in Medicine
Editorial Board, PharmacoEconomics
Joint Clinical Assessment Subgroup, Health Technology Assessment Coordination Group, European Commission.
ISPOR Europe Programme Committee Member
Peer-review for European and international top-in field journals (HTA and clinical). External peer-review for the Innovational Research Incentive Scheme - Veni, Netherlands Organisation for Scientific Research.
Member, Irish Cancer Epidemiology Network (ICEN).
Member, National Cancer Control Programme (NCCP) Technology Review Group.
Member, The Piperska Group, a pan-European collaborative aiming to address/advance pharmaceutical-related financial sustainability of healthcare systems
Member, National Prostate Cancer Research Consortium
Member, HIQA Expert Advisory Group, HTA Assessment of National Screening Programme for Atrial Fibrillation
Awards and Honours
'Murdoch McKenzie' Prize for Highest Academic Grades in Pharmacy Undergrad Degree (1989-1991 inclusive), University of Sunderland, UK.
'Mawson Proctor' Award for Highest Academic Grades in Pharmaceutical Chemistry & Pharmacognosy (Pharmacy), University of Sunderland, UK.
'Boots' The Chemist Prize, for Highest Academic Grades in First Year of Pharmacy Undergrad Degree, University of Sunderland, UK.
Memberships
Member of The Pharmaceutical Society of Ireland.
Member of The Royal Pharmaceutical Society of Great Britain.