Professor Donal Sexton
Clinical Associate Professor, Clinical Medicine
Clinical Associate Professor, Medical Gerontology
Publications and Further Research Outputs
Peer-Reviewed Publications
Conlon E, Fitzgerald C, Hintze J, Elhassan EAE, Sexton DJ, O'Leary E, O'Kelly P, O'Neill JO, Egan J, Houlihan DD, Murray D, McCormick PA, Morris PG, Raghallaigh SN, Little D, Conlon PJ, Moloney FJ, O'Neill JP., High frequency and mortality of head and neck malignancy in organ transplant recipients in Ireland - A national cohort study., American journal of otolaryngology, 44, (4), 2023, p103827
Nowak N, De Looze C, O'Halloran A, Kenny RA, Sexton DJ., The association between kidney function, cognitive function, and structural brain abnormalities in community-dwelling individuals aged 50"+"is mediated by age and biomarkers of cardiovascular disease., Cardiovascular research, 2023, pcvad060
Sandys V, Bhat L, O'Hare E, Ninan A, Doyle K, Kelly S, Conlon P, Sexton D, Edwards C, McAleese P, O'Seaghdha C., Pilot Study of a Wearable Hydration Monitor in Haemodialysis Patients: Haemodialysis Outcomes & Patient Empowerment Study 02., Digit Biomark, 7, (1), 2023, p18-27
Sandys V, Sexton D, O'Seaghdha C., Artificial intelligence and digital health for volume maintenance in hemodialysis patients., Hemodialysis international. International Symposium on Home Hemodialysis, 26, (4), 2022, p480-495
Dyer AH, Laird E, Hoey L, Hughes CF, McNulty H, Ward M, Strain JJ, O'Kane M, Tracey F, Molloy AM, Cunningham C, Sexton DJ, McCarroll K, Reduced kidney function is associated with poorer domain-specific cognitive performance in community-dwelling older adults, International Journal of Geriatric Psychiatry, 2022
Menzies S, O'Leary E, Callaghan G, Mansoor N, Deady S, Murad A, Lenane P, O'Neill J, Lally A, Houlihan DD, Murray S, Sexton DJ, McCormick PA, Egan JJ, O'Neill JP, Conlon PJ, Moloney FJ., A population-based comparison of organ transplant recipients in whom cutaneous squamous cell develops versus those in whom basal cell carcinoma develops., Journal of the American Academy of Dermatology, 86, (6), 2022, p1377-1379
Sandys V, Sexton DJ, Sexton DJ., Learning Methodological Lessons from Exemplar Studies in Nephrology: PEXIVAS and Sample Size Calculation., Kidney360, 3, (8), 2022, p1427-1430
Jennifer Scott, Enock Havyarimana, Albert Navarro-Gallinad, Arthur White, Jason Wyse, Jos van Geffen, Michiel van Weele, Antonia Buettner, Tamara Wanigasekera, Cathal Walsh, Louis Aslett, John D Kelleher, Julie Power, James Ng, Declan O'Sullivan, Lucy Hederman, Neil Basu, Mark A Little, Lina Zgaga, The association between ambient UVB dose and ANCA-associated vasculitis relapse and onset, Arthritis Research & Therapy, 24, (1), 2022, p1 - 14
Chin Lin Ng, Alaeldin Abdalla, Greta Galambosi, Cuffe S, Doyle B, Griffin B, Sexton DJ.B, , Acute kidney Injury due to Alectinib, an Anaplastic Lymphoma Kinase inhibitor, Journal of Onco-Nephrology, 2021
Ebad CA, Brennan D, Chevarria J, Hussein MB, Sexton D, Mulholland D, Doyle C, O'Kelly P, Williams Y, Dunne R, O'Seaghdha C, Little D, Morrin M, Conlon PJ., Is Bigger Better? Living Donor Kidney Volume as Measured by the Donor CT Angiogram in Predicting Donor and Recipient eGFR after Living Donor Kidney Transplantation., Journal of transplantation, 2021, 2021, p8885354
Kielty J, Ryan P, Sexton DJ, Kelly Y., Hypokalaemic paralysis as the initial clinical presentation of Sjogren's syndrome induced distal renal tubular acidosis, 2021
Donal J Sexton, Eileen McBrearty, Patrick O'Connor, George Mellotte, The Impact of a National Surgical Mask Wearing Policy on COVID-19 Transmission in Haemodialysis Units in the Republic of Ireland, Kidney International Reports, 2021
BMC Nephrology, Springer Nature, [eds.], 2020
Murray SL, O'Leary E, De Bhailís ÁM, Deady S, Daly FE, O'Kelly P, Williams Y, O'Neill JP, Sexton DJ, Conlon PJ, Cancer survival in kidney transplant recipients in Ireland., Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2020
Sexton DJ, Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis., The New England journal of medicine, 2020
Julio Chevarria, Donal J Sexton, Susan L Murray, Chaudhry E Adeel, Patrick O'Kelly, Yvonne E Williams, Conall M O'Seaghdha, Dilly M Little, Peter J Conlon, Calcium and phosphate levels after kidney transplantation and long-term patient and allograft survival, Clinical Kidney Journal, 2020
Cosgrave N, Mellotte G, Griffin B, Little MA, Kenny RA, Sexton DJ. , Deep Learning analysis of derived cardiac function metrics for the detection of chronic kidney disease and subsequent outcome prediction in community dwelling individuals. , JASN Supplement (Journal of the American Society of Nephrology) 2020., American Society of Nephrology (ASN) Kidney Week 2020 , Virtual online, 2020
Murray SL, Daly FE, O'Kelly P, O'Leary E, Deady S, O'Neill JP, Dudley A, Rutledge NR, McCormick A, Houlihan DD, Williams Y, Morris PG, Sexton DJ, Conlon PJ, The impact of switching to mTOR inhibitor-based immunosuppression on long-term non-melanoma skin cancer incidence and renal function in kidney and liver transplant recipients., Renal failure, 2020
A Hudson, Sexton DJ, O'Seaghdha CM, Patient Engagement with a Digital Health Intervention to Optimise Interdialytic Fluid Management in Ambulatory Haemodialysis patients, JASN Supplement (Journal of the American Society of Nephrology) 2019, American Society of Nephrology Kidney Week 2019 , Washington DC USA, 2019
Donal J. Sexton, Patrick O'Kelly, Yvonne Williams, William D. Plant, Marie Keogan, Khairin Khalib, Brendan Doyle, Anthony Dorman, Caner Süsal, Christian Unterrainer, James Forde, Richard Power, Gordon Smith, Ponnusamy Mohan, Mark Denton, Colm Magee, Declan G. de Freitas, Dilly Little, Conall M. O'Seaghdha, Peter J. Conlon, Progressive improvement in short", medium" and long"term graft survival in kidney transplantation patients in Ireland " a retrospective study, Transplant International, 32, (9), 2019, p974--984
Chevarria J, Sexton DJ, Constandache C, Adeel Ebad C, Murray S, Keelan S, O'Shea H, Deady S, Conlon PJ., Renal Function after Radical Cystectomy and Ileal Conduit Diversion, Nephrology Dialysis Transplantation, European Renal Association, 2019
Chaudhry E, Sexton DJ, Conlon P, Donor Kidney Renal Volume Predicts Recipient and Donor Graft Function at 1 year., JASN Supplement (Journal of the American Society of Nephrology) , American Society of Nephrology Kidney Week 2019 , Washington DC USA, 2019
Sexton DJ, O'Kelly P, Murray S, Daly F, McCormack PA, Morris P, Houlihan DG, O'Neill JP, Conlon PJ., Variation in non-melanoma skin cancer incidence by treatment modality in those receiving multiple kidney transplants., JAMA Dermatology , 2019
Stapleton CP, Heinzel A, Guan W, van der Most PJ, van Setten J, Lord GM, Keating BJ, Israni AK, de Borst MH, Bakker SJL, Snieder H, Weale ME, Sexton DJ, International Genetics and Translational Research in Transplantation Network, The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population., American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2019
James Paul O'Neill, Donal J. Sexton, Eamonn O'Leary, Patrick O'Kelly, Susan Murray, Sandra Deady, Fergus Daly, Yvonne Williams, Ben Dean, Conall Fitzgerald, Aizuri Murad, Nazish Mansoor, Jim O. O'Neill, Jim Egan, Diarmaid D. Houlihan, P. Aiden McCormick, Patrick G. Morris, Siona Ni Raghallaigh, Dilly Little, Fergal J. Moloney, Peter J. Conlon, Post"transplant malignancy in solid organ transplant recipients in Ireland, The Irish Transplant Cancer Group, Clinical Transplantation, 33, (10), 2019
Edwards C, O'Seaghdha CM, Sexton DJ, Evaluation of a Mobile Digital Health Intervention to Capture Patient-Reported Data and Symptoms and Optimise Fluid Management in Haemodialysis, JASN Supplement (Journal of the American Society of Nephrology) 2019, American Society of Nephrology Kidney Week 2019 , 2019
Sexton DJ, O'Kelly P, O'Leary E, Murray S, Deady S, Daly F, Egan J, Houlihan DD, McCormick PA, Morris PG, Ni Raghallaigh S, Moloney FJ, O'Neill JP, Conlon PJ, Variation in Nonmelanoma Skin Cancer Incidence by Treatment Modality Among Patients Receiving Multiple Kidney Transplants., JAMA dermatology, 2019
Sexton DJ, O'Kelly P, Kennedy C, Denton M, de Freitas DG, Magee C, O'Seaghdha CM, Conlon PJ, Assessing the discrimination of the Kidney Donor Risk Index/Kidney Donor Profile Index scores for allograft failure and estimated glomerular filtration rate in Ireland's National Kidney Transplant Programme., Clinical kidney journal, 2019
Sexton DJ, Does the Hazard of Non Melanoma Skin Cancer Vary by Treatment Modality in End Stage Kidney Disease?", Irish National Transplant Society Meeting , 2018, 2019
Chevarria, J, Chaudrey A, Sexton DJ, Conlon P, Association of Post Transplant Calcium and Phosphate Levels with Graft Outcomes, JASN Supplement (Journal of the American Society of Nephrology) 2018, American Society of Nephrology Kidney Week 2018, 2018
Sexton, D.J. and de Freitas, D.G. and Little, M.A. and McHugh, T. and Magee, C. and Conlon, P.J. and O'Seaghdha, C.M., Direct-Acting Oral Anticoagulants as Prophylaxis Against Thromboembolism in the Nephrotic Syndrome, Kidney International Reports, 3, (4), 2018, p784-793
Sexton DJ, Murray S, Conlon PJ, Trough Tacrolimus levels in Kidney Transplant Recipients and Non Melanoma Skin Cancer Risk over Follow up., JASN Supplement (Journal of the American Society of Nephrology) 2018, American Society of Nephrology Kidney Week 2018, 2018
Foley RN, Sexton DJ, Drawz P, Ishani A, Reule S, Race, Ethnicity, and End-of-Life Care in Dialysis Patients in the United States., Journal of the American Society of Nephrology : JASN, 2018
Kennedy C, Wong L, Sexton DJ, Cowman J, Oglesby I, Kenny M, Conlon PJ, Kenny D, Successful kidney transplantation normalizes platelet function., Clinical kidney journal, 2018
Foley RN, Sexton DJ, Reule S, End-of-Life Care in Young Dialysis Patients, JASN Supplement (Journal of the American Society of Nephrology) 2018, American Society of Nephrology Kidney Week 2018, 2018
Sexton D.J., Canney M., Kenny R.M., Limitations of observational data in interpreting SPRINT results?reply, JAMA Internal Medicine, 178, (1), 2018, p155-
Menzies S, O'Leary E, Deady S, Callaghan G, MacEochagain C, Gadallah B, Lenane P, Lally A, Houlihan D, Morris PG, Sexton DJ, McCormick A, Egan JJ, O'Neill JP, Conlon PJ, Moloney FJ, Post transplant skin cancer incidence has halved, for both BCC and SCC, since the turn of the century, British Journal of Dermatology, British Dermatology Society Meeting, 2018
Sexton DJ, Conlon PJ, Progressive Improvement in short, medium, and long term graft survival in kidney transplantation patients in Ireland., British Transplant Society Scientific Meeting, 2018, 2018
Reule S, Sexton DJ, Foley RN, Outcomes among those receiving veterans affairs insurance in the United States., JASN Supplement (Journal of the American Society of Nephrology) 2018, American Society of Nephrology Kidney Week 2018, 2018
Daly, FE, O'Kelly, P, O'Neill JP, Murray S, Deady S, O'Leary E, Egan JJ, McCormick A, Houlihan D, Morris PG, Moloney FJ, Sexton DJ, Conlon PJ, The Influence of a Conversion to Sirolimus-based Immunosuppression on non-melanoma Skin Cancer Incidence in Kidney Transplant Recipients over long term follow up, American Journal of Transplantation, American Transplantation Congress 2018., 2018
Claire Kennedy, Wong L, Sexton DJ, Cowman JC, Kenny M, Conlon PJ, Kenny D, Successful Kidney Transplantation Normalizes Platelet Function., JASN Supplement (Journal of the American Society of Nephrology) 2017, American Society of Nephrology Kidney Week 2017, 2017
Sexton DJ, O'Kelly P, Kennedy C, de Freitas DG, O'Seaghdha CM, Conlon PJ. , KDPI and Allograft eGFR in Deceased Donor Kidney Transplant Recipients over Follow Up: 1995-2013., JASN Supplement (Journal of the American Society of Nephrology) 2017, American Society of Nephrology Kidney Week 2017, 2017
Sexton DJ, Canney M, O'Connell MDL, Moore P, Little MA, O'Seaghdha CM, Kenny RA, Generalisability of SPRINT to community dwelling individuals for adverse events. , Journal of Human Hypertension , British Society of Hypertension, 2017
Aird J, Kennedy C, Sexton DJ, Reeve J, Halloran P, de Freitas D, Doyle B. , Molecular Assessment of Transplant Renal Biopsies and Comparison with Histology. , LABORATORY INVESTIGATION, 2017
Sexton DJ, Generalisability of SPRINT to Community Dwelling Individuals over the Age of 75: Informing Estimation of Baseline Adverse Event Risk, The Irish Nephrology Society Annual Scientific Meeting, 2017
Sexton DJ, Blood Pressure Control in the Elderly: Lessons to be Learned in Treating Frail Patients, European Peritoneal Dialysis Conference , 2017
Sexton DJ, Kenny RM, O'Seaghdha CM, Cost-Effectiveness of Intensive versus Standard Blood-Pressure Control., The New England journal of medicine, 2017
Sexton DJ, Canney M, Kenny RA, Little MA, O'Seaghdha CM., RAAS Blockade in Community Dwelling Elders and the Importance of "Sick Day Rules" , JASN Supplement (Journal of the American Society of Nephrology) 2017, American Society of Nephrology Kidney Week 2017, 2017
Donal Sexton, Rose Anne Kenny, Generalisability of SPRINT to community dwelling individuals for adverse events. , Journal of Human Hypertension , British Society of Hypertension, 2017
Foley RN, Drawz PE, Sexton DJ, Reule S, Race, Ethnicity, and End-of-Life Care in US Dialysis Patients, 2000 to 2011., JASN Supplement (Journal of the American Society of Nephrology) 2017, American Society of Nephrology Kidney Week 2017, 2017
Sexton DJ, Reule S, Foley RN, End-Stage Kidney Disease From Scleroderma in the United States, 1996 to 2012., Kidney international reports, 2017
Wanigasekera T, Grainger RJ, Sexton DJ, Magee C, IVIG Associated Aseptic Meningitis in a Renal Transplant Patient., Case reports in transplantation, 2017
Sexton DJ, O'Kelly P, Deady S, Conlon PJ, Non Melanoma Skin Cancer Risk Following Graft Failure in Renal Transplant Recipients in Ireland, 1994-2015: Does the Hazard Vary during Periods of Dialysis?, JASN Supplement (Journal of the American Society of Nephrology) 2018, American Society of Nephrology Kidney Week 2017, 2017
Wong L, Counihan A, O'Kelly P, Sexton DJ, O'Seaghdha CM, Magee C, Little D, Conlon PJ, The impact of donor and recipient weight incompatibility on renal transplant outcomes., International urology and nephrology, 2017
Stapleton CP, Kennedy C, Sexton DJ, Cavaleri P, Conlon PJ. , A Donor and Recipient Genome-Wide Association Study of Renal Allograft Function. , JASN Supplement (Journal of the American Society of Nephrology) 2017, American Society of Nephrology Kidney Week 2017, 2017
Sexton DJ, Canney M, O'Connell MDL, Moore P, Little MA, O'Seaghdha CM, Kenny RA, Injurious Falls and Syncope in Older Community-Dwelling Adults Meeting Inclusion Criteria for SPRINT., JAMA internal medicine, 177, 2017, p1385-
Sexton DJ, Canney M, Cotter EJ, Doran PP, Murray PT, Little MA, Determinants of Urinary Soluble CD163 over Time in an Intensive Care Cohort, JASN Supplement (Journal of the American Society of Nephrology) 2016, American Society of Nephrology Kidney Week 2016, 2016
Donal Sexton, The Epidemiology of End Stage Kidney Disease in the United States, 1995-2012, The Irish Nephrology Society Annual Scientific Meeting, 2016
Sexton DJ, Canney M, Kenny RA, Little MA, O'Seaghdha CM, eGFR Agreement and Mortality Discrimination in Community Dwelling Obese Individuals , JASN Supplement (Journal of the American Society of Nephrology) 2016, American Society of Nephrology Kidney Week 2016, 2016
Canney M, Sexton DJ, O'Leary N, Kenny RA, Little MA, O'Seaghdha CM, Distribution of Cystatin C and Creatinine with Advancing Age, JASN Supplement (Journal of the American Society of Nephrology) 2016, American Society of Nephrology Kidney Week 2016, 2016
Canney M, O'Connell MDL, Sexton DJ, O'Leary N, Kenny RA, Little MA, O'Seaghdha CM, Graded Association between Kidney Function and Postural Blood Pressure Instability , JASN Supplement (Journal of the American Society of Nephrology) 2016, American Society of Nephrology Kidney Week 2016, 2016
Sexton DJ, Canney M, Little MA, O'Seaghdha CM, Kenny RA, Generalisability of SPRINT to Community Dwelling Individuals over the Age of 75: Informing Estimation of Baseline Adverse Event Risk, JASN Supplement (Journal of the American Society of Nephrology) 2016, American Society of Nephrology Kidney Week 2016, 2016
Sexton DJ, O'Reilly MW, Geoghegan P, Kinsella SM, Moran PJ, O'Regan AW, Serum fibroblastic growth factor 23 in acute Sarcoidosis and normal kidney function., Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2016
Sexton DJ, Lowney AC, O'Seaghdha CM, Murphy M, O'Brien T, Casserly LF, McQuillan R, Plant WD, Eustace JA, Kinsella SM, Conlon PJ, Do patient-reported measures of symptoms and health status predict mortality in hemodialysis? An assessment of POS-S Renal and EQ-5D., Hemodialysis international. International Symposium on Home Hemodialysis, 2016
Gleeson J, Crippa IA, Sexton DJ, Fontana V, Taccone F, Creteur J, Vincent JL, Determinants of Renal Recovery and Mortality in Patients Undergoing Continuous Renal Replacement Therapy in the ICU, Critical Care Medicine, European Society of Intensive Care scientific meeting Oct 2015, 2015
Foley RN, Reule S, Sexton DJ, Hospice and Race for End-of-Life Care in U.S. Dialysis Patients, JASN Supplement (Journal of the American Society of Nephrology) 2015, American Society of Nephrology Kidney Week 2015, 2015
Sexton DJ, Reule S, Foley RN, ESRD in Nonagenarians in the United States, 1995 Through 2010, JASN Supplement (Journal of the American Society of Nephrology) 2015, American Society of Nephrology Kidney Week 2015, 2015
Sexton DJ, Reule S, Foley RN, ESRD from Scleroderma in the United States 1995-2010 , JASN Supplement (Journal of the American Society of Nephrology) 2015, American Society of Nephrology Kidney Week 2015, 2015
Donal Sexton, Predictive Ability of Self-Rated Health and Symptom Burden for Mortality in Haemodialysis, 2015
Foley RN, Sexton DJ, Reule S, Solid C, Chen SC, Collins AJ, End-stage renal disease attributed to acute tubular necrosis in the United States, 2001-2010., American journal of nephrology, 2015
Reule S, Sexton DJ, Solid CA, Chen SC, Foley RN, ESRD due to Multiple Myeloma in the United States, 2001-2010., Journal of the American Society of Nephrology : JASN, 2015
Sexton DJ, Reule S, Foley RN, Intermittent Abnormal Kidney Function and Mortality in Community Dwelling Individuals, JASN Supplement (Journal of the American Society of Nephrology) 2015, American Society of Nephrology Kidney Week 2015, 2015
Sexton DJ, Lowney AC, O'Seaghdha CM, Kinsella S, Conlon PJ, Predictive Ability of Self-Rated Health and Symptom Burden for Mortality in Hemodialysis., JASN Supplement (Journal of the American Society of Nephrology) 2015, American Society of Nephrology Kidney Week 2015, 2015
Sexton DJ, Reule S, Solid CA, Chen SC, Collins AJ, Foley RN, End-stage renal disease from hemolytic uremic syndrome in the United States, 1995-2010., Hemodialysis international. International Symposium on Home Hemodialysis, 2015
Foley RN, Reule S, Sexton DJ, End-Stage Renal Disease from Membranous Nephropathy in the United States, 1995 to 2010 , JASN Supplement (Journal of the American Society of Nephrology) 2015, American Society of Nephrology Kidney Week 2015, 2015
Sexton DJ, Reule S, Solid C, Chen SC, Collins AJ, Foley RN, ESRD from lupus nephritis in the United States, 1995-2010., Clinical journal of the American Society of Nephrology : CJASN, 2014
Sexton DJ, Reule S, Solid C, Collins AJ, Foley RN, End-stage renal disease from human immunodeficiency virus"associated nephropathy in the United States, 2001 through 2010., JAMA internal medicine, 2014
Sexton D, Tofacitinib versus methotrexate in rheumatoid arthritis., The New England journal of medicine, 2014
Reule S, Sexton DJ, Ibrahim HN, Simultaneous Liver and Kidney Transplantation in the Nephrologist Led Era: Characteristics and Outcomes, JASN Supplement (Journal of the American Society of Nephrology) 2014, American Society of Nephrology Kidney Week 2014, 2014
Sexton DJ, How should we modify recommended renin-angiotensin-aldosterone system inhibition when facing the cardiorenal syndrome?, Circulation. Heart failure, 2014
Sexton DJ, Reule S, Foley RN, Kidney Function and Mortality Risk in Community Dwelling Individuals: Hierarchical Importance of Threshold Values, JASN Supplement (Journal of the American Society of Nephrology) 2014, American Society of Nephrology Kidney Week 2014, 2014
Reule S, Sexton DJ, Solid C Chen SC, Collins AC, Foley RN., End-Stage Renal Disease Due to Multiple Myeloma in the United States, 2000-2010. , JASN Supplement (Journal of the American Society of Nephrology) 2013, American Society of Nephrology Kidney Week 2013, 2013
Sexton D, Correlation versus agreement; protein/creatinine ratio in spot urine and 24-hour urine protein., Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2013
Sexton DJ, Tolvaptan in autosomal dominant polycystic kidney disease., The New England journal of medicine, 2013
Reule S, Sexton DJ, Solid C Chen SC, Collins AC, Foley RN., End-Stage Renal Disease from Autosomal Dominant Polycystic Kidney Disease in the United States, 2000-2010., JASN Supplement (Journal of the American Society of Nephrology) 2013, American Society of Nephrology Kidney Week 2013, 2013
Sexton DJ, Heart failure: predictive ability of edema for volume overload., The American journal of medicine, 2013
Sexton DJ, Reule S, Solid C Chen SC, Collins AC, Foley RN, End Stage Renal Disease due to HIVAN in the United States 2000-2010, JASN Supplement (Journal of the American Society of Nephrology) 2013, American Society of Nephrology Kidney Week 2013, 2013
Sexton DJ, Reule S, Solid C Chen SC, Collins AC, Foley RN, End Stage Renal Disease due to Lupus Nephritis in the United States 2000-2010. , JASN Supplement (Journal of the American Society of Nephrology) 2013, American Society of Nephrology Kidney Week 2013, 2013
. Sexton DJ, Talbot A, O'Regan AW, Serum Fibroblastic Growth Factor 23 in Acute Sarcoidosis and Normal Kidney Function, JASN Supplement (Journal of the American Society of Nephrology) 2012, American Society of Nephrology Kidney Week 2012, 2012
Moran PJ, Geoghegan P, Sexton DJ, O'Regan A, A skin rash to remember., BMJ (Clinical research ed.), 2012
Sexton DJ, Plant WD, Eustace JA, Clarkson MR, Quiz page December 2012: bilateral kidney enlargement and acute kidney injury in a patient with HIV infection., American journal of kidney diseases : the official journal of the National Kidney Foundation, 2012
Geoghegan P, Sexton DJ, Giblin L, O'Regan A, Taught a lesson by taut skin., BMJ (Clinical research ed.), 2012
Sexton DJ, Kinsella SM, Eustace JA, Serum phosphate varies with degree of proteinuria in nephrotic syndrome and is associated with elevated pulse wave velocity., Journal of nephrology, 2012
Sexton DJ, Eustace JA, Insulin resistance in primary nephrotic syndrome; is kidney function truly normal?, Pediatric nephrology (Berlin, Germany), 2012
Geoghegan P, Ni Sheaghdha E, Sexton DJ, Reddan DN, Lappin D, A Comparative Analysis of Two Methods of Blood Pressure Measurement in an Adult Diabetic Population., JASN Supplement (Journal of the American Society of Nephrology) 2012, American Society of Nephrology Kidney Week 2012, 2012
Sexton DJ, Long EB, Khan N, Parfrey N, Barry J, Plant WD, Kenny L, Juxtaglomerular cell rennin-secreting tumour in a twin pregnancy - 1st trimester severe hypertension, proteinuria and hypokalaemia, Kidney International Supplement 2011, World Congress of Nephrology 2011, 2011
Sexton DJ, Eustace JA., Determinants of elevated D-Dimer levels in patients with the nephrotic syndrome without clinical evidence of thrombosis., Kidney International Supplement 2011, World Congress of Nephrology 2011, 2011
Sexton DJ, Kinsella SM, Eustace JA. , Serum Phosphate in the Nephrotic Syndrome Varies with Degree of Proteinuria but Is Independently Associated with High Pulse Wave Velocity. , JASN Supplement (Journal of the American Society of Nephrology) 2011, American Society of Nephrology Kidney Week 2011, 2011
Sexton DJ, Vaughan KM, Moran C, Plant WD, Clarkson MR, Eustace JA, Haemodialysis-induced syncope due to Chiari II malformation., NDT plus, 2011
Sexton DJ, Kinsella SM, Harrington A, Plant WD, Clarkson MR, Eustace JA, The association of hyperphosphataemia with elevated pulse wave velocity in long standing nephrotic syndrome. , Kidney International Supplement 2011, World Congress of Nephrology 2011, 2011
Sexton DJ, Plant WD, Mazur MJ, Clarkson MC, Eustace JA, Long Term Decrement in eGFR Following Leptospirosis Associated Acute Kidney Injury in the South of Ireland., JASN Supplement (Journal of the American Society of Nephrology) 2011, American Society of Nephrology Kidney Week 2011, 2011
Sexton DJ, Eustace JA, Measurement of D-dimer Levels in the Nephrotic Syndrome, JASN Supplement (Journal of the American Society of Nephrology) 2011, American Society of Nephrology Kidney Week 2011, 2011
Sexton DJ, Mazur MJ, The timing of resolution of secondary hyperparathyroidism post kidney transplant, 'Early or never!, JASN Supplement (Journal of the American Society of Nephrology) 2009, American Society of Nephrology Kidney Week 2009, 2009
Chakkera H, Sexton DJ, Epidemiological risk factors for the new onset of Diabetes Mellitus post kidney transplantation (NODAT)., American Society of Nephrology Kidney Week 2009, 2009
*Friel AM, Hynes PG, Sexton DJ, Smith TJ, Morrison JJ, Expression Levels of mRNA for Rho A/Rho Kinase and Its Role in Isoprostane-Induced Vasoconstriction of Human Placental and Maternal Vessels, Reproductive Science, 2, 2008, p179-88-
Doheny HC, O'Reilly MJ, Sexton DJ, Morrison JJ, THG113.31, a specific PGF2alpha receptor antagonist, induces human myometrial relaxation and BKCa channel activation., Reproductive biology and endocrinology : RB&E, 2007
*Friel AM, Sexton DJ, O'Reilly MW, Smith TJ, Morrison JJ. , Rho A/Rho kinase: human umbilical artery mRNA expression in normal and pre-eclamptic pregnancies and functional role in isoprostane-induced vasoconstriction, Reproduction, 132, (1), 2006, p168-76
*Friel AM, O'Reilly MW, Sexton DJ, Morrison JJ. , Specific PGF (2alpha) receptor (FP) antagonism and human uterine contractility in vitro, British Journal of Obstetrics & Gynaecology, 112, (8), 2005, p1034-42
Lynch CM, Sexton DJ, Hession M, Morrison JJ, Incidence of obesity and influence of BMI on birth weight and mode of delivery in a European primagravid population, The Journal of The Society for Gynecologic Investigation, 2005
Sexton DJ, Friel AM, Morrison JJ, The Effects of CRH in the Presence and Absence of CRH-1 and CRH-Antagonists in Human pregnant myometrium, The Journal of the Society of Gynecological Investigation , 2005
Lynch CM, Sexton DJ, Hession M, Morrison JJ, Obesity and multigravidity in a European Obstetric population, The Journal of The Society for Gynecologic Investigation, 2005
Friel AM, Sexton DJ, Smith TJ, Morrison JJ, Vasoconstrictor effects of isoprostanes in human small placental arteries and the rho kinase calcium sensitization pathway, The Journal of The Society for Gynecologic Investigation, 2005
. Sexton DJ, O'Reilly MW, Friel AM, Morrison JJ, 17 a - Hydroxyprogesterone Caproate (17P) and Human Myometrial Contractility In Vitro, The Journal of The Society for Gynecologic Investigation, 2004
Sexton DJ, O'Reilly MW, Doheny H, Morrison JJ, PgF 2 a Receptor Antagonism and BK CA Channel Activity In Human Uterus During Pregnancy., The Journal of The Society for Gynecologic Investigation, 2004
Friel AM, Sexton DJ, O'Reilly MW, Smith TJ, Morrison JJ, Rho Kinase and Protein Kinase Inhibition on Human Umbilical Artery Tone, The Journal of The Society for Gynecologic Investigation, 2004
O'Reilly MW, Sexton DJ, Friel AM, Morrison JJ, The Uterorelaxant Effects of THG113, A Novel Specific PGF 2 a receptor (FP) Antagonist, on Isolated Uterine contractions In Human Pregnant and Non-Pregnant Tissue, The Journal of The Society for Gynecologic Investigation, 2004
Friel AM, Sexton DJ, O'Reilly MW, Smith JJ, Morrison JJ., Selectivity of Protein Kinase Inhibition on Human Umbilical Artery Tone, The Journal of The Society for Gynecologic Investigation, 2004
Sexton DJ, O'Reilly MW, Doheny H, Morrison JJ. , PgF 2 a Receptor Antagonism and BK CA Channel Activity In Human Uterus During Pregnancy. , The Journal of The Society for Gynecologic Investigation, 2004
Sexton DJ, O'Reilly MW, *Friel AM, Morrison JJ, Functional effects of 17alpha-hydroxyprogesterone caproate (17P) on human myometrial contractility in vitro, Reproductive Biology & Endocrinology, 20, (1), 2004, p7-
Sexton DJ, O'Reilly MW, Friel AM, Morrison JJ, 17 a - Hydroxyprogesterone Caproate (17P) and Human Myometrial Contractility In Vitro, The Journal of The Society for Gynecologic Investigation, 2004
Sexton DJ, O'Reilly MW, Doheny H, Morrison JJ, Novel Pg 2& Receptor antagonism and BK C& channel in human uterus during pregnancy. , British Journal Of Obstetrics and Gynaecology, 2003
Non-Peer-Reviewed Publications
Belinda Hernández, Donal Sexton, Frank Moriarty, Niall Cosgrave, Aisling O'Halloran, Christine McGarrigle, Siobhan Scarlett, Rose Anne Kenny, High-risk categories for COVID-19 and their distribution by county in Republic of Ireland-evidence from the TILDA study, The Irish Longitudinal Study on Ageing, Trinity College Dublin, 2020
EIT Health is a component of EIT which is funded by The European Union, EIT Health Editorial - "Collaborate to Innovate: driving the adoption of AI in healthcare", https://thinktank.eithealth.eu/conference-room/editorial-collaborate-to-innovate-driving-the-adoption-of-ai-in-healthcare/, EIT Health is a component of EIT which is funded by The European Union, 2020
Sexton DJ, Bio-informatics in Nephrology, 24th Annual Health Informatics Society of Ireland Conference & Scientific Symposium Medics Stream, 2019, 2019
Donal Sexton, Ageing and the Kidney, Insights from TILDA Biomedical Data, Biogerontology for Clinicians, Mercer Institute for Successful Ageing, 2018
Foley RN, Reule S, Sexton DJ, Hospice and Race for End-of-Life Care in U.S. Dialysis Patients, JASN Supplement (Journal of the American Society of Nephrology) 2015, American Society of Nephrology Kidney Week 2015, 2015
Donal Sexton, Scott Reule, Rob Foley, End Stage Kidney Disease in Nonagenarians in the United States 1995 through 2010., American Society of Nephrology Kidney Week 2019 , 2014
Research Expertise
Projects
- Title
- Informing Chronic Kidney Disease health policy in Ireland: Linkage of large datasets to study the interaction between ageing and kidney function
- Summary
- This Project is a HRB funded postdoctoral fellowship (ARPP) which encompasses machine learning analysis of data from the Irish Longitudinal Study on Ageing (TIDA) to inform healthcare policy such as healthcare resource planning for kidney disease services in Ireland.
- Funding Agency
- HRB
- Date From
- July 2019
- Date To
- July 2022
- Title
- Deep Learning Analysis of Retinal Vessel Segmentation patterns and their association with Cardiovascular Disease as part of the TILDA Study
- Summary
- This is a collaboration between TILDA and ADAPT to apply deep learning image analysis (Artificial Intelligence) to retinal photographic images to discern associations primarily with cardiovascular disease, aging and mortality.
- Funding Agency
- The Irish Longitudinal Study on Ageing (TILDA)
- Date From
- Jan 2021
- Title
- Planning Slaintecare Kidney Services based on data from the Irish Longitudinal Study on Ageing (TILDA).
- Summary
- This project is to define the prevalence and incidence of chronic kidney disease in Ireland and by region within Ireland in order for the HSE to effectively plan resource allocation for kidney disease in Slaintecare.
- Funding Agency
- The National Renal Office of the HSE
- Date From
- Jan 2020
Recognition
Awards and Honours
Winner of best abstract in category at the British Transplant Society Meeting, Brighton, UK, 2018. This was a moderated poster relating to long-term kidney allograft function in Ireland.
Awarded the Vincent Dolan Medal for best clinical research presentation at the Irish Nephrology Society Annual Scientific Meeting 2017.
Awarded an Advances in Research conference bursary by the American Society of Nephrology (ASN) to attend the "Advances in Research Conference: Precision Medicine in Renal Diseases" and ASN Kidney Week 2017.
Best Research Presentation at the Irish Transplant Society Meeting
Awarded the Dimitrios Oreopoulos Geriatric Nephrology Travel Support grant by the American Society of Nephrology
The American Society of Nephrology Training Program Directors Executive Committee invited me to present "ESRD in Nonagenarians in the US 1995 through 2010"
Awarded the American Society of Nephrology (ASN) Bursary, ASN Kidney Week 2013. (Advances in Geriatric Nephrology).
Awarded the Irish Nephrology Society Research Bursary 2012.
Graduation in 1st place in the final medical class at the National University of Ireland Galway, achieving first class honours in all degree subjects [Medicine, Surgery, Paediatrics, Obstetrics & Gynaecology, Ophthalmology, General Practice] and a first class honours degree overall.
2006 Awarded the national Dr Henry Hutchinson Steward Medical Scholarship for Surgery.
2006 Awarded the national Dr Henry Hutchinson Steward Medical Scholarship for Obstetrics and Gynaecology.
2005 Awarded the national Dr Henry Hutchinson Steward Medical Scholarship for Paediatrics.
2005 Awarded the national Dr Henry Hutchinson Steward Medical Scholarship for Psychiatry 2005.
2002 Awarded third place in the national Dr Henry Hutchinson Steward Medical Scholarship for Anatomy.
2006 Gold medal awarded in Paediatrics at The National University of Ireland Galway.
2006 Gold medal awarded in Psychiatry at The National University of Ireland Galway.
NUI Galway University Examination Prize for 1st place overall in MB BCH BAO in 2006
1st place Penultimate Year examinations overall. (Scholar of the University Prize)
1st place Paediatrics overall NUIGalway.
1st place Psychiatry overall NUIGalway 2005
1st place Paediatrics Objective Structured Clinical Examination
1st place Obstetrics & Gynaecology Objective Structured Clinical Examination & MCQ.
1st place in Intercalated BSc in Pharmacology final examinations
1st place overall in 3rd Year Medicine examinations NUIGalway
1st place Pharmacology 3rd year Medicine 2002
1st place Neuro-Physiology NUIGalway.
1st place Neuro-Anatomy NUIGalway
1st place overall in 2nd year examinations: Anatomy, Physiology and Biochemistry and also individually in the following; Gross Anatomy, Clinical Anatomy, Histology, Embryology.
1st place overall in Anatomy 1st year Medicine.
1st place Human Biology; composite of Histology, Embryology, Biology, Parasitology, Physics.
Awarded the IPSEN Pharmaceutical Company Research Fellowship in Reproductive Health.
Winner of Health Research Board (HRB) of Ireland Poster Presentation January 2004.
All-Ireland school leaving certificate science quiz winner, St Josephs College Galway. I was one of a team of three students who won this national science quiz for leaving certificate students. (We also won the city and county quizzes before progressing to national quiz)
Awarded 1st place in National Senior house officer application - Royal College of Physicians of Ireland
1st Place in National Specialist Training Scheme Application for Nephrology & General Medicine - RCPI
Memberships
1. The American Society of Nephrology. 2. The Royal College of Physicians of Ireland (RCPI).