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Trinity College Dublin, The University of Dublin

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Professor Brian O'Connell
Professor, Dental Science
Dean of Health Sciences, Fac Office - Faculty of Health Sciences

Publications and Further Research Outputs

Peer-Reviewed Publications

Meaney S, Connell BO, Elfadil S, Allen F, A qualitative investigation into patients' perspectives on edentulousness., Gerodontology, 34, (1), 2017, p79 - 85 Journal Article, 2017 DOI

Michael O'Sullivan, Brian C O'Connell, Multidisciplinary management of hypodontia , Prim Dent J, 6, (1), 2017, p62 - 73 Journal Article, 2017

O'Sullivan V and O'Connell BC, Water fluoridation, dentition status and bone health of older people in Ireland, Community Dentistry & Oral Epidemiology, 43, (1), 2015, p58 - 67 Journal Article, 2015 TARA - Full Text

Al-Awadhi, E.A., Garvey, T.M., Alhag, M., Claffey, N.M., O'Connell, B., Efficacy of the Nance appliance as an anchorage-reinforcement method, American Journal of Orthodontics and Dentofacial Orthopedics, 147, (3), 2015, p330-338 Journal Article, 2015

McAuliffe P, Kim JH, Diamond D, Lau KT and O'Connell BC, A sleep bruxism detection system based on sensors in a splint, Journal of oral Rehabilitation, 42, (1), 2015, p34 - 39 Journal Article, 2015

Mcauliffe, P., Kim, J.H., Diamond, D., Lau, K.T., O'Connell, B.C., A sleep bruxism detection system based on sensors in a splint - pilot clinical data, Journal of Oral Rehabilitation, 42, (1), 2015, p34-39 Journal Article, 2015

Gallagher S, O'Connell BC ,O'Connell AC, Assessment of occlusion after placement of stainless steel crowns in children--a pilot study, Journal of Oral Rehabilitation, 41, (10), 2014, p730 - 736 Journal Article, 2014 DOI

Hashem A, Kelly A, O'Connell B, O'Sullivan M, Impact of moderate and severe hypodontia and amelogenesis imperfecta on quality of life and self-esteem of adult patients., Journal of dentistry, 41, (8), 2013, p689-94 Journal Article, 2013

O'Connell B, Prosthodontics at the crossroads: is this a 'golden age'?, Journal of the Irish Dental Association, 59, (2), 2013, p84-6 Journal Article, 2013

Harris D, Höfer S, O'Boyle CA, Sheridan S, Marley J, Benington IC, Clifford T, Houston F, O'Connell B, A comparison of implant-retained mandibular overdentures and conventional dentures on quality of life in edentulous patients: a randomized, prospective, within-subject controlled clinical trial., Clinical oral implants research, 24, (1), 2013, p96 - 103 Journal Article, 2013 DOI

Canning T, O'Connell BC, Houston F, O'Sullivan M, The effect of skeletal pattern on determining articulator settings for prosthodontic rehabilitation: an in vivo study., The International journal of prosthodontics, 24, (1), 2011, p16-25 Journal Article, 2011

Sharkey S, Kelly A, Houston FJ, O'Sullivan M, Quinn F and O'Connell BC, A Radiographic Analysis of Implant Component Misfit, International Journal of Oral & Maxillofacial Implants, 26, (4), 2011, p807 - 815 Journal Article, 2011

Sharkey S, Kelly A, Houston F, O'Sullivan M, Quinn F, O'Connell B, A radiographic analysis of implant component misfit., The International journal of oral & maxillofacial implants, 26, (4), 2011, p807-15 Journal Article, 2011

Condon M, Bready M, Quinn F, O'Connell BC, Houston FJ, O'Sullivan M, Maxillary anterior tooth dimensions and proportions in an Irish young adult population., Journal of oral rehabilitation, 2010 Journal Article, 2010 DOI

Brennan M, Houston FJ, O'Sullivan M and O'Connell BC, Patient Satisfaction and Oral Health Related Quality of Life Outcomes of Implant Overdentures and Fixed Complete Dentures, International Journal of Oral & Maxillofacial Implants, 25, (4), 2010, p791 - 800 Journal Article, 2010

Kim Jung Ho, McAuliffe P, O'Connell BC, Diamond D and Lau KT, Development of Wireless Bruxism Monitoring Device Based on Pressure Sensitive Polymer, Sensors and Actuators A, 163, (2), 2010, p486-492 Journal Article, 2010 TARA - Full Text

Cellular & Molecular Biomechanics. in, editor(s)T. Clive Lee, Peter F. Niederer , Engineering for Medics and Biologists - An ESEM Primer: Studies in health technology and informatics, Online, IOP Press Online, 2010, pp202-213 , [Campbell VA, O'Connell B] Book Chapter, 2010 URL

Campbell VA, O'Connell B, Cellular and molecular biomechanics., Technology and health care , 18, (3), 2010, p233-243 Journal Article, 2010 DOI

Atef A. Hashem, Brian O'Connell, June Nunn, Anne O'Connell, Therese Garvey, Michael O'Sullivan, Tooth agenesis in patients referred to an Irish tertiary care clinic for the developmental dental disorders, Journal of the Irish Dental Association, 56, (1), 2010, p23 - 27 Journal Article, 2010 TARA - Full Text

Brennan M, Houston FJ, O'Sullivan M and O'Connell BC, Demographics of Implant Placement and Complications of a Patient Sub-Group in a Dental Hospital Population, Journal of the Irish Dental Association, 56, (2), 2010, p85 - 92 Journal Article, 2010

Fitzgerald M, O'Sullivan M, O'Connell BC and Houston FJ, Accuracy of Bone Mapping and Guided Flapless Implant Placement in Human Cadavers Using a Model-Based Planning Procedure, International Journal of Oral & Maxillofacial Implants, 25, (5), 2010, p999 - 1006 Journal Article, 2010

J.G. McGarry, P. Maguire, V.A. Campbell, B.C. O'Connell, P.J. Prendergast, S.P., Stimulation of Nitric Oxide Mechanotransduction in Single Osteoblasts Using Atomic Force Microscopy, Journal of Orthopedic research, 26, 2008, p513 - 521 Journal Article, 2008

Szlávik V, Szabó B, Vicsek T, Barabás J, Bogdán S, Gresz V, Varga G, O'Connell B,and Vag J, Differentiation of primary human submandibular gland cells cultured on basement, Tissue Eng Part A, 14, (11), 2008, p1915 - 1926 Journal Article, 2008

E. Byrne, E. Farrell, L. A. McMahon, M. G. Haugh, F. J. O'Brien, V. A. Campbell, P. J. Prendergast and B. C. O'Connell, Gene expression by marrow stromal cells in a porous collagen-glycosaminoglycan scaffold is affected by pore size and mechanical stimulation., J Mater Sci: Mater Med, 19, 2008, p3455 - 3463 Journal Article, 2008

Vanda Szlávik, János Vág, Károly Markó, Kornél Demeter, Emília Madarász, Imre Oláh, Tivadar Zelles, Brian C. O'Connell, Gábor Varga, Matrigel-induced acinar differentiation is followed by apoptosis in HSG cells., J Cell Biochem , 103, 2008, p284 - 295 Journal Article, 2008

B O'Connell and M O'Sullivan, Have Teeth Will Travel:Dental Tourism--Informing the Public, J Ir Dent Assoc, 53, 2007, p180 - 182 Journal Article, 2007

Vag, J., Byrne, E.M., Hughes, D.H., Hoffman, M.H., Ambudkar, I., Maguire, P. and O'Connell, B.C. , Morphological and Functional Differentiation of HSG cells: Role of Extracelleular Matrix and trpc1, J Cell Physiol , 212, (2), 2007, p416 - 423 Journal Article, 2007

P Maguire, JI Kilpatrick, G Kelly, PJ Prendergast VA Campbell, BC O'Connell and S Jarvis, Direct Mechanical Measurement of Geodesic Structures in Rat Mesenchymal Stem Cells, HFSP Journal, 1, (3), 2007, p181 - 191 Journal Article, 2007

Davis, S.T. and O'Connell, B.C., The Effect of Two Root Canal Sealers on the Retention of Glass Fibre Endodontic Posts, J. Oral Rehab, 34, 2007, p468 - 473 Journal Article, 2007 URL TARA - Full Text

Deirdre H. Fitzgerald-Hughes, David C. Coleman and Brian C. O Connell, Identification of differentially-expressed proteins in derivatives of Candida albicans displaying a stable histatin-3 resistant phenotype, Antimicrobial Agents and Chemotherapy, 51, (8), 2007, p2793 - 2800 Journal Article, 2007

Farrell, E., Byrne, E.M., Fischer, J., O'Brien, F.J., O'Connell, B.C., Prendergast, P.J. and Campbell, V.A, A comparison of the osteogenic potential of adult rat mesenchymal stem cells cultured in 2-D and on 3-D collagen glycosaminoglycan scaffolds. , Technology and Health Care, 15, 2007, p19 - 31 Journal Article, 2007

Byrne D, Jacobs S, O'Connell B, Houston F, Claffey N, Preloads generated with repeated tightening in three types of screws used in dental implant assemblies, Journal of Prosthodontics, 15, (3), 2006, p164 - 171 Journal Article, 2006

Hashem, A.A., Claffey, N.C. and O'Connell, B.C., Pain and Anxiety Following the Placement of Dental Implants, J. Oral. Maxfac. Implants, 21, (6), 2006, p943 - 950 Journal Article, 2006

Farrell, E., Prendergast, P., O'Brien, F., O'Connell, B.C. and Campbell, V. A, Collagen-Glycosaminoglycans Scaffold Supports Adult Rat Mesenchymal Stem Cell Differentiation Along the Osteogenic and Chondrogenic Routes, Tissue Engineering, 12, (3), 2006, p459 - 468 Journal Article, 2006

Restoration of non-vital teeth in, editor(s)M. O'Sullivan , Quintessentials of Dental Practice: Fixed Prosthodontics in Dental Practice, London, Quintessence Publishing Co., 2005, pp139 - 158, [O'Connell, B.C.] Book Chapter, 2005

Yamagishi, H., Fitzgerald, D.H., Sein, T., Walsh, T.J. and O'Connell, B.C., Saliva affects the antifungal activity of exogenously added histatin 3 towards Candida albicans, FEMS Microbiology Lett, 244, (1), 2005, p207 - 212 Journal Article, 2005

Dagg, H., O'Connell, B., Claffey, N., Byrne, D. and Gorman, C., The influence of some different factors on the accuracy of shade selection., Journal of Oral Rehabilitation, 31, 2004, p900 - 904 Journal Article, 2004

Davis, S. and O'Connell, B.C., The provisional crown, J Irish Dent Assoc, 50, (4), 2004, p167 - 172 Journal Article, 2004 TARA - Full Text

Fitzgerald, D.H., Coleman, D.C. and O'Connell, B.C., Susceptibility of Candida dubliniensis to Salivary Histatin 3, Antimicrob Agents Chemother, 47, (1), 2003, p70 - 76 Journal Article, 2003

Zheng, C., O"Connell, B.C., Baum, B.J., Inclusion of Moloney murine leukemia virus elements upstream of the transgene cassette in an E1- deleted adenovirus leads to an unusual genomic integration in epithelial cells, Virology, 313, (2), 2003, p460 - 472 Journal Article, 2003

Fitzgerald, D.H., Coleman, D.C. and O'Connell, B.C., Binding, Internalisation and Degradation of Histatin 3 in histatin resistant derivatives of Candida albicans, FEMS Microbiol Lett., 220, (2), 2003, p247 - 256 Journal Article, 2003

O"Connell, B.C., Zheng, C., Jacobson-Kram, D., Baum, B.J., Distribution and toxicity resulting from adenoviral administration to a single salivary gland in adult rats, J. Oral Path Med, 32, (7), 2003, p414 - 421 Journal Article, 2003

Schonherr, E., Schaefer, L., O'Connell, B.C. and Kresse, H., Matrix Metalloproteinase Expression by Endothelial Cells in Collagen Lattices Changes During Co-Culture with Fibroblasts and upon Induction of Decorin Expression, J. Cell Physiol., 187, (1), 2001, p37 - 47 Journal Article, 2001

Zheng, C., Hoque, A.T.M., Braddon, V.R., Baum, B.J. and O'Connell, B.C., Evaluation of Salivary Gland Acinar and Ductal Cell Specific Promoters In vivo with Recombinant Adenoviral Vectors, Hum. Gene Ther., 12, 2001, p2215 - 2223 Journal Article, 2001

Zheng, C., Goldsmith, C.M., O'Connell, B.C. and Baum, B.J., Adenoviral Vector Cytotoxicity Depends in Part on the Transgene Encoded, Biochemical and Biophysical Research Communications, 274, 2000, p767 - 771 Journal Article, 2000

Zheng, C., Baum, B.J., Iadarola, M.J. and O'Connell, B.C., Genomic Integration and Long Term Expression by a Modified Adenoviral Vector, Nature Biotechnol, 18, (2), 2000, p176 - 180 Journal Article, 2000

Baum, B.J., Goldsmith, C.M., Hoque, A.T.M., Wellner, R.B., Baccaglini, L., Ding, C., Yamano, S., Zheng, C., Aframian, D.J. and O'Connell, B.C., Salivary Glands as a Model for Craniofacial Applications of Gene Transfer, Int J. Oral & Maxillofac Surg, 29, 2000, p163 - 166 Journal Article, 2000

Liu, X., Wang, W., Singh, B.B., Lockwich, T., Jadlowiec, J., O'Connell, B.C., Wellner, R., Zhu, M.X. and Ambudkar, I.S., Trp1, a Candidate Protein for the Store-Operated Ca(+2) Influx Mechanism in Salivary Gland Cells, J. Biol. Chem., 275, (5), 2000, p3403 - 3411 Journal Article, 2000

Hoque, A.T.M.S., Liu, X., Kagami, H. Swaim, W.D., Wellner, R.B., O'Connell, B.C., Ambudkar, I.S., and Baum, B.J., Construction and function of a recombinant adenovirus encoding a human aquaporin 1-green fluorescence protein fusion product, Cancer Gene Ther., 7, 2000, p476 - 485 Journal Article, 2000

He, L., Liu, J., Collins, I., Sanford, S., O'Connell, B.C., Benham, C.J., and Levens, D., Loss of FBP Function Arrests Cell Proliferation and Extinguishes c-myc Expression, EMBO J, 19, (5), 2000, p1034 - 1044 Journal Article, 2000

Jung, D.W., Hecht, D., Ho, S.W., O'Connell, B.C., Kleinman, H.K. and Hoffman, M.P., PKC and ERK 1/2 Regulate Amylase Promoter Activity During Differentiation of a Salivary Gland Cell Line, J.Cell Physiol., 185, (2), 2000, p215 - 225 Journal Article, 2000

Schönherr, E., O'Connell, B.C., Schittny, J., Robenek, H., Fastermann, D., Fisher, L.W., Plenz, G., Vischer, P., Young, M.F. and Kresse, H., Paracrine or virus-mediated induction of decorin expression by endothelial cells contributes to tube formation and prevention of apoptosis in collagen lattices, Eur. J. Cell Biol., 78, 1999, p44 - 45 Journal Article, 1999

Wang, S., Baum, B.J., Kagami, H., Zheng, C., O'Connell, B.C., and Atkinson, J.C., Effect of clodronate on macrophage depletion and adenoviral-mediated transgene expression in salivary glands, J. Oral Pathol. Med., 28, 1999, p145 - 151 Journal Article, 1999

DeNichilo, M.O., Katz, B., O'Connell, B.C. and Yamada, K.M., Adenovirus-Mediated Gene Delivery of pp125FAK into Cultured Human Macrophages Deficient in This Protein Directs p50CSK Localization to Focal Contacts and Regulated MAP Kinase, J. Cell Physiol., 178, 1999, p164 - 172 Journal Article, 1999

Connell, A.C., Baccaglini, L., Fox, P.C., O'Connell, B.C., Kenshalo, D., Oweisy, H., Hoque, A.T.M., Sun, D., Herscher, L.L., Braddon, V.R., Delporte, C. and Baum, B., Efficacy of Adenovirus-mediated Transfer of the Human Aquaporin 1 cDNA to Irradiated Parotid Glands of Non-human Primates, Cancer Gene Ther, 6, (6), 1999, p505 - 513 Journal Article, 1999

Baum, B.J. and O'Connell, B.C., Vivo Gene Transfer to Salivary Glands, Crit. Rev. Oral Biol.Med., 10, (3), 1999, p276 - 283 Journal Article, 1999

Sommer, B., Kuznetsov, S.A., Gehron Robey, P., O'Connell, B.C., Cristiano. R.J. and Young, M.F., Efficient Gene Transfer into Normal Human Skeletal Cells Using Recombinant Adenovirus and Conjugated Adenovirus-DNA Complexes, Calc. Tissue Int., 64, 1999, p45 - 49 Journal Article, 1999

Wang, W., O'Connell, B.C., Dykeman, R., Sakai., Delporte, C., Swaim, W., Zhu, X., Birnbaumer, L. and Ambudkar, I., Cloning of TRP1b isoform from rat brain: immunodetection and localization of the endogenous Trp 1 protein, Am. J. Physiol, 45, (5), 1999, pC969 - C979 Journal Article, 1999

Brennan, M.T., O'Connell, B.C., Rams, T.E. and O'Connell, A.C., Management of Gingival Overgrowth Associated with Generalized Enamel Defects in a Child, J Clin Pediatr Dent, 23, (2), 1999, p97 - 102 Journal Article, 1999

Xu, YY, Histatin 3-Mediated Killing of Candida Albicans: Effect of Extracellular Salt Concentration on Binding and Internalization, Antimicrobial Agents and Chemotherapy, 43, 1999, p2256 - 2262 Journal Article, 1999

Baum, B.J. and O'Connell, B.C., The need to introduce gene therapy to the dental curriculum, Eur J Dent Educ, 3, 1999, p49 - 51 Journal Article, 1999

Mannes, A.J., Caudle, R.M., O'Connell, B.C. and Iadarola, M.J., Adenoviral Gene Transfer to Spinal Cord Neurons: Intrathecal vs. Intraparenchymal Administration, Brain Res., 793, (1-2), 1998, p1 - 6 Journal Article, 1998

Baum, B.J., Atkinson, J., Baccaglini, L., Berkman, M., Brahim, J., Davis, V., Lancaster, H., Marmary, Y., O'Connell, A., O'Connell, B., Wang, S., Xu, Y., Yamagishi, H. and Fox, P., The Mouth is a Gateway to the Body: Gene Therapy in 21st Century Dental Practice, CDA Journal, 26, (6), 1998, p455 - 460 Journal Article, 1998

O'Connell, B.C., Lillibridge, C.D., Ambudkar, I. and Kruse, D., Somatic Gene Transfer to Salivary Glands, Ann. NY Acad. Sci., 842, 1998, p171 - 180 Journal Article, 1998

Zheng, C., Hoffman, M.P., McMillan, T., Kleinman, H.K. and O'Connell, B.C., Growth Factor Regulation of the Amylase Promoter in Differentiating Salivary Gland Acinar Cells, J. Cell Physiol., 177, 1998, p628 - 635 Journal Article, 1998

Kagami, H., Atkinson, J.A., Handelman, B., Yu, S., Baum, B. and O'Connell, B.C., Repetitive Adenovirus Administration to Parotid Gland: Role of Immunological Barriers and Induction of Oral Tolerance, Hum. Gene Ther., 9, 1998, p305 - 313 Journal Article, 1998

O'Connell, A.C., Lillibridge, C.D., Zheng, C., Baum, B.J., O'Connell, B.C. and Ambudkar, I.S., -Irradiation-Induced Cell Cycle Arrest and Cell Death in a Human Submandibular Gland Cell Line: Effect of E2F1 Expression, J. Cell Physiol, 177, (2), 1998, p264 - 273 Journal Article, 1998

O'Connell, B.C., Redman, R.S. and Zheng, C., In Vivo Use of Adenoviral Vectors: Effects on Salivary Gland Structure, Eur. J Morphol., 36, 1998, p55 - 80 Journal Article, 1998

Delporte, C., O'Connell, B.C., He, X., Lancaster, H.E., O'Connell, A.C., Agre, P. and Baum, B.J., Increased Fluid Secretion Following Transfer of the Aquaporin-1 cDNA to Irradiated Rat Salivary Glands, Proc. Natl. Acad. Sci. USA 94, 1997, p3268 - 3273 Journal Article, 1997

Delporte, C., Panyutin, I.G., Sedelnikova, O.A., Lillibridge, C.D., O'Connell, B.C. and Baum, B.J., Triplex Forming Oligonucleotides Can Modulate Aquaporin-5 Gene Expression in Epithelial cells, Antisense and Nucleic Acid Drug Development, 7, 1997, p523 - 529 Journal Article, 1997

Lillibridge, C.D., and O'Connell, B.C., In Human Salivary Cells, Overexpression of E2F1 Overcomes an IFN-- and TNF--Induced Growth Arrest But Does Not Result in Complete Mitosis, J. Cell. Physiol., 172, 1997, p343 - 350 Journal Article, 1997

Delporte, C., Miller, G., Kagami, H., Lillibridge, C.D., O'Connell, B.C., Atkinson, J.C. and Baum, B.J., Safety of Salivary Gland-Administered Replication-Deficient Recombinant Adenovirus in Rats, J. Oral Pathol. Med., 27, 1997, p34 - 38 Journal Article, 1997

Gene Transfer to Salivary Glands in, Studies in Stomatology and Craniofacial Biology, IOS Press, 1997, pp615 - 631, [O'Connell, B.C. and Baum, B.J.] Book Chapter, 1997

Delporte, C., O'Connell, B.C., He, X., Ambudkar, I.S., Agre, P. and Baum, B.J., Adenovirus-mediated Expression of Aquaporin 5 in Epithelial Cells, J. Biol. Chem, 271, (36), 1996, p22070 - 22075 Journal Article, 1996

Kagami, H., O'Connell, B.C. and Baum B.J., Evidence for the Systemic Delivery of a Transgene Product from Salivary Glands, Hum. Gene Ther, 7, 1996, p2177 - 2184 Journal Article, 1996

Wu, A.J., Chen, Z.J., Tsokos, M., O'Connell, B.C., Ambudkar, I.S. and Baum, B.J., Interferon- induced Cell Death in a Cultured Human Salivary Gland Cell Line, J. Cell Physiol, 167, 1996, p297 - 304 Journal Article, 1996

O'Connell, B.C., Xu, T., Walsh, T.J., Sein, T., Mastrangeli, A., Crystal, R.G., Oppenheim, F.G. and Baum, B.J., Transfer of a Gene Encoding the Anticandidal Protein Histatin 3 to Salivary Glands, Hum. Gene Ther, 7, 1996, p2255- Journal Article, 1996

Adesanya, M.R., Redman, R.S., Baum, B.J. and O'Connell, B.C., Acute Inflammatory Response in Adenovirus-mediated Gene Transfer to Rat Salivary Glands, Hum. Gene Ther, 7, (9), 1996, p1085 - 1093 Journal Article, 1996

O'Connell, B.C., Ten Hagen, K.G., Lazowski, K.W., Tabak, L.A. and Baum, B.J., Facilitated DNA Transfer to Rat Submandibular Gland in Vivo and GRP Gene Regulation, Am. J. Physiol., 268, 1995, pG1074 - G1078 Journal Article, 1995

Sharma, A., O'Connell, B.C., Tabak, L.A. and Bedi, G.S., Expression of a Functional Rat Salivary Cystatin S Polypeptide in Escherichia coli, Arch. Oral. Biol., 40, (7), 1995, p639 - 644 Journal Article, 1995

Baum, B.J. and O'Connell, B.C., The Impact of Gene Therapy on Dentistry, JADA, 126, 1995, p179 - 189 Journal Article, 1995

Mastrangeli, A.M., O'Connell, B.C., Fox, P.C., Aladib, W., Baum, B.J., and Crystal, R.G., In vivo gene transfer to rat salivary gland, Am. J. Physiol., 266, 1994, pG1146 - G1155 Journal Article, 1994

O'Connell, B.C., and Tabak, L.A., A comparison of serine and threonine O-glycosylation by UDPGalNAc: Polypeptide N-acetylgalactosaminyltransferase, J. Dent. Res., 72, 1993, p1554 - 1558 Journal Article, 1993

Salivary Gland-Specific Gene Expression in, U.S./Latin American Workshop on Salivary Research, Albuquerque, C&A Press, 1993, pp66 - 75, [O'Connell, B.C. and Tabak, L.A.] Book Chapter, 1993

O'Connell, B.C., and Tabak, L.A., Separation of glycopeptides from in vitro O-glycosylation reactions using C18 cartridges, Anal. Biochem., 210, 1993, p423 - 425 Journal Article, 1993

O'Connell, B.C., Hagen, F., and Tabak, L.A., The influence of flanking amino acid sequence on O-glycosylation by UDPGalNAc: Polypeptide N-acetylgalactosaminyltransferase, J. Biol. Chem., 267, 1992, p25010 - 25018 Journal Article, 1992

O'Connell, B., Tabak, L.A., and Ramasubbu, N., The influence of flanking sequences on O-glycosylation, Biochem. Biophys. Res. Commun., 180, 1991, p1024 - 1024 Journal Article, 1991

Non-Peer-Reviewed Publications

Brian O'Connell, The Future Starts Now--a Smart Splint, Eastman Institute of Oral Health Centennial, Rochester, New York, 9 June, 2017, EIOH Invited Talk, 2017

Brian O'Connell, The Daily Grind-an Update on the Management of Bruxism, The Greater new York Academy of Prosthodontics, New York, USA, 2 December , 2016, GNYAP Invited Talk, 2016

O'Connell, B., Developmental defects of the dentition-diagnosis to management, South-Eastern Branch, PGMDB., Kilkenny, December, 2004 Invited Talk, 2004

O'Connell, B., Restoration of Endodontically-Treated Teeth-the Evidence, Destination Ireland, University of Minnesota, October, 2004 Invited Talk, 2004

O'Connell, B., Restorative Dentistry in the Molecular Age, University of Rochester, Annual Alumni Conference, Florida, November, 2003 Invited Talk, 2003

O'Connell, B., Bioengineering and Restorative Dentistry, International College of Dentists, Annual Conference, Dublin, June, 2003 Invited Talk, 2003

O'Connell, B., Orthodontic, Periodontic, Prosthodontic-the Interrelationship, European Begg Society of Orthodontics, Annual Conference, Dublin, May, 2003 Invited Talk, 2003

O'Connell, B., Restoration of Endodontically Treated Teeth, South Eastern Branch, IDA, Scientific Conference, Waterford, 22/2/2002, 2002 Invited Talk, 2002

O'Connell, B., Restorative Dentistry in the Molecular Age, American Dental Society of Europe, Annual Conference, Prague, June, 2002 Invited Talk, 2002

O'Connell, B., Functional Genomics, Gordon Research Conference: Saliva and Salivary Glands, Ventura, CA, 16/2/01, 2001 Invited Talk, 2001

O'Connell, B., Genes and the Prosthodontist, American College of Prosthodontists, Annual Session, New Orleans, 2/11/01, 2001 Invited Talk, 2001

O'Connell, B., Salivary gland development, regeneration and repair-summary and future directions, 16th International Conference on Oral Biology, Chantilly, Virginia, 12/4/00, 2000 Invited Talk, 2000

O'Connell, B., Saliva in Health and Disease-Repair and regeneration, Swedish Dental Association, Annual Congress, Stockholm, 27/10/00, 2000 Invited Talk, 2000

O'Connell, B., Treatment Planning in Prosthodontics, Munster Branch, IDA. Annual Scientific Session, Cork, 22/9/00, 2000 Invited Talk, 2000

O'Connell, B., Fear of Failure in Prosthodontics, Midland Western Postgraduate Dental Foundation. Annual Meeting, Dromoland Co. Clare, 11-12/2/00, 2000 Invited Talk, 2000

O'Connell, B., Gene Therapy for Salivary Gland Dysfunction, 5th European Symposium on the Application of Saliva in Clinical Practice and Research, Egmond aan Zee, Netherlands, 20/5/99, 1999 Invited Talk, 1999

O'Connell, B., Viral-mediated Gene Transfer to the Salivary Glands, University of Manchester, Biological Sciences-Physiology section, 15/12/99, 1999 Invited Talk, 1999

O'Connell, B., Recent Developments in Clinical Research on Saliva, International Association for Dental Research. Annual Session, Vancouver, 12/3/99, 1999 Invited Talk, 1999

O'Connell, B., Gene Transfer Technology and the Oral Cavity, Latin American Association for Salivary Research, 3rd International Meeting, Vina del Mar, Chile, 15/11/99, 1999 Invited Talk, 1999

O'Connell, B., Gene Transfer and Gene Therapy, Oral Biology at the Turn of the Century: Misconceptions, Truths, Challenges and Prospects, Interlaken, Switzerland, 20/8/98, 1998, European Research Group for Oral Biology Invited Talk, 1998

O'Connell, B., Advances in Gene Therapy, FDI, 86th Annual World Dental Congress; Scientific Frontiers in Clinical Dentistry, Barcelona, Spain, 9/10/98, 1998 Invited Talk, 1998

O'Connell, B., Genetic Regulation and Gene Expression of Salivary Proteins, U.S.-China Workshop on the Role of Saliva in Oral Health, Beijing, 19/10/98, 1998 Invited Talk, 1998

O'Connell, B., Salivary Gland Specific Gene Expression-In vivo Gene Transfer as a Tool, Gordon Research Conference: Saliva and Salivary Glands, Ventura, CA, 25/2/97, 1997 Invited Talk, 1997

O'Connell, B., Use of in Vivo Gene Transfer for the Study of Salivary Gland Function, 2nd Stenone Symposium, Cagliari, Italy, 24/5/97, 1997 Invited Talk, 1997

O'Connell, B., Prospects for Salivary Gland Gene Therapy, Graduate Student Seminar, University of Rochester, New York, 29/4/97, 1997 Invited Talk, 1997

O'Connell, B., Gene Transfer; How to Teach an Old Gland New Tricks, International Association for Dental Research, Annual Session, Orlando, 21/3/97, 1997 Invited Talk, 1997

O'Connell, B., Therapeutic Interventions: Gene Transfer to Salivary Glands, Salivary Gland Biogenesis and Function, Airlie, Virginia, 10/11/96, 1996 Invited Talk, 1996

O'Connell, B., DNA as a Therapeutic Agent for Oral Disease, University of Texas Health Science Center, San Antonio, 21/5/96, 1996 Invited Talk, 1996

O'Connell, B., Gene-based Approaches to the Treatment of Oral Disease, Scientific Frontiers in Dentistry Symposium, Bethesda, 14/6/96, 1996 Invited Talk, 1996

O'Connell, B., Gene Therapy and Oral Diseases, Academy of Prosthodontics, Annual Meeting, Tucson, 19/5/95, 1995 Invited Talk, 1995

O'Connell, B., An Integrated Approach to Salivary Gland Repair (Symposium, Plenary lecture). Salivary Gland Gene Therapy (Lunch and Learning), American Association for Dental Research, Annual Session, San Antonio, 10-11/3/95, 1995 Invited Talk, 1995

O'Connell, B., Gene Therapeutics: Supportive Therapies for Cancer Patients, International Society for Oral Oncology, 9th Annual Meeting, Bethesda, 3/6/94, 1994 Invited Talk, 1994

O'Connell, B., Overview of Gene Therapy (Lecture). Salivary Gland Gene Therapy (Seminar), University of Minnesota, Minneapolis, 6-7/10/94, 1994 Invited Talk, 1994

O'Connell, B., Salivary Gland Gene Therapy, University of Alabama, Birmingham, 1/8/94, 1994 Invited Talk, 1994

O'Connell, B., Adenovirus-Mediated Gene Transfer to the Salivary Glands, Forsyth Dental Center, Boston, 15/7/93, 1993 Invited Talk, 1993

Research Expertise


  • Title
    • Investigative and Therapeutic Gene Transfer to the Salivary Glands
  • Funding Agency
    • NIH Grant-NIDCR Project Z01-DE00675-01-03
  • Date From
    • 1996
  • Date To
    • 1999
  • Title
    • Construction of Adenovirus Vectors for the Study of Gene Control and Protein Function
  • Summary
  • Funding Agency
    • NIH-NIDCR Research and Development Contract.
  • Date From
    • 6/97
  • Date To
    • 5/00
  • Title
    • Production and Testing of Adenovirus Vectors for Clinical Use
  • Funding Agency
    • NIH-NIDCR Research and Development Contract.
  • Date From
    • 6/97
  • Date To
    • 5/99
  • Title
    • Provost Award
  • Funding Agency
    • Trinity College Dublin
  • Date From
    • 1999
  • Date To
    • 1999
  • Title
    • In vivo function and regulation of salivary antimicrobial proteins
  • Summary
  • Funding Agency
    • Health Research Board-Project Grant.
  • Date From
    • 2000
  • Date To
    • 2003
  • Title
    • Real Time PCR equipment
  • Funding Agency
    • Health Research Board-Co-investigator for equipment grant.
  • Date From
    • 2000
  • Date To
    • 2000
  • Title
    • Antifungal Mechanism of Human Salivary Histatin
  • Funding Agency
    • Health Research Board-Project Grant
  • Date From
    • 2002
  • Title
    • Mechanobiology of Tissue Engineering
  • Summary
    • Theme Co-ordinator. Trinity Centre for Bioengineering (TCBE)
  • Funding Agency
    • Higher Education Authority-PRTLI
  • Date From
    • 2002
  • Date To
    • 2007
  • Title
    • Regulation of Salivary Gland Gene Expression
  • Funding Agency
    • Wellcome Trust-Travelling Fellowship
  • Date From
    • 2003
  • Date To
    • 2005
  • Title
    • Cells Under Strain
  • Summary
    • Project leader, Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN)
  • Funding Agency
    • Science Foundation Ireland (SFI)
  • Date From
    • 2004
  • Title
    • Differential cellular response to nanoscale engineered titanium surfaces
  • Summary
    • Co-Principal Investigator
  • Date From
    • 2005
  • Date To
    • 2009
  • Title
  • Summary
    • Superior monitoring & analysis relayed through sensors providing longitudinal information on nocturnal tooth grinding
  • Funding Agency
    • Enterprise Ireland
  • Date From
    • October 2008
  • Date To
    • October 2009


ALBICANS; Bioengineering and radiologic imaging; Biological Engineering; Biology; Biomaterials; Biomechanics; Biomechanics, Biomedical Engineering; Biomedical Engineering; Biomedical sciences; Biotechnology; Bone; CANDIDA SPP; Cell Communication; Cell Lines; Culture Collections, Microbial, Cell, Tissue and Germplasm; Dental education; Dentistry; DNA; Engineering underpinning biomedicine; Eukaryotic gene regulation; Gene Cloning; Gene therapy; Genetic Engineering; Genomes, Genomics; HISTIDINE-RICH POLYPEPTIDES; HUMAN SALIVARY HISTATIN-5; Implants; INFECTION; Medical Devices; Molecular Biology; Molecular Cloning; Mycology and fungal pathogenesis; Nano Biotechnology; Oral and Maxillofacial Surgery; Oral clinical research; Oral Diseases; Oral diseases and Oral medicine; Oral Health; Peptides; Prosthetic Devices (General); Restorative dentistry and materials science; Saliva and Salivary gland; Salivary Glands; Stem Cell; Stem Cell biology and hematopoiesis; Temporomandibular Joint Disorders; Tissue Culture; Tissue Engineering; Transgene Expression; Transgenic Animals



Journal of Dental Research (Editorial Board)

Antimicrobial Agents and Chemotherapy (Reviewer)

Critical Reviews in Oral Biology and Medicine (Reviewer)

American Heart Association (Grant reviewer)

Anatomical Record (Reviewer)

Archives of Oral Biology (Reviewer)

International Journal of Cancer (Reviewer)

Oral Bioscience and Medicine (Editorial Board)

Oral Diseases (Editorial Board)

Awards and Honours

Fellow, American College of Prosthodontists 1999

Fellow, Trinity College, Dublin 2002

College Scholar (U.C.C.) 1980

Edward Gurr Prize (U.C.C.) 1981

U.C.C. Scholarship 1982

Gold Medal Restorative Dentistry (U.C.C.) 1984

Peel Memorial Award (U.C.C.) 1984

Bloor Award (U. Rochester) (First Place Biochemistry Doctorate) 1993

NIDR Travel Award 1995

AADR/IADR Hatton Award, First Place, (International Young Investigator) 1992


International Association for Dental Research

American Association for the Advancement of Science

American Society for Biochemistry and Molecular Biology

Fellow of the American College of Prosthodontists