Molecular & Cellular Biology (MIU44002)

This module is part of the core curriculum.

Name  Details 
Module Name  MIU44002 - Molecular and Cell Biology 
Module Credit Value  10 Credits 
Module Coordinator  Dr. Sinead Corr 

Dr. Alastair Fleming 

Dr. Kim Roberts 

Dr. Carsten Kroger 

Dr. Anna Ershova

Dr. Gary Moran , Dental School 

Contact Hours 

30 lectures 

Recommended Reading List for self-guided study 

Students will be provided with primary research articles and scientific reviews on specialised research topics for self-guided study. 


Short Content Overview 

This module builds on the core concepts of bacterial and eukaryotic gene expression studied in the Junior Sophister year and introduces students to "up to the minute" developments in research in this area. Lecture topics include the dynamic genomes of bacteria and eukaryotic organisms with an emphasis on yeasts, the compaction and reorganisation of chromatin and the bacterial nucleoid during gene expression, chromatin modification, biogenesis of RNA, including RNA polymerase II transcription, RNA processing, and export form the nucleus. Lectures on the interaction of viruses with the host cell machines are provided and students are introduced to the world of small RNA and the role of small RNAs in viral pathogenesis. 

Students in their fourth year have an opportunity to explore, in detail, the major areas of Microbiology under the themes of (a) Molecular and Cellular Biology, and (b) Microbial Pathogenicity. The themes are covered in two Core Modules: MIU44002, and MIU44003. Lectures on the core themes are compulsory for all students. Each 10 ECTS module requires lecture attendance by students, self-directed study guided by recommended reading material, and further reading beyond the course.