A novel device to control in-situ the thermal gelation and concentration of cell-seeded hydrogels
Project coordinator(s)Dr. Tony Robinson
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Tel: +353 1 896 3919
Dr. Danny Kelly
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Tel: +353 1 896 3947
Dr. Fergal O'Brien
Post-graduate StaffDr. Conor Buckley
DescriptionIt is believed that injuries to cartilage predispose a person to osteoarthritis in later life and eventually to a requirement for joint replacement surgery. Injectable chondrocyte-seeded hydrogels can potentially be used to fill cartilage defects with a functional repair tissue. Ensuring that the hydrogel has the appropriate mechanical properties in situ (e.g. stiffness, permeability, porosity) is critical for successful repair. The objective of this project is to develop a clinical device capable of controlling dependant mechanical properties of the construct.
Funding BodyEnterprise Ireland (Proof of Concept Grant)